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					Sudden Cardiac Death

General Reviews

Lopshire JC, Zipes DP (2006) Sudden cardiac death: better understanding of risks,
mechanisms, and treatment. Circulation 2006;114 1134-1136.

Dekker LRC et al. (2006) Familial sudden death is an important risk factor for primary
ventricular fibrillation: a case-control study in acute myocardial infarction patients.
Circulation 2006; 114 1140-1145

Muller D et al. (2006) How sudden is sudden cardiac death? Circulation 2006 ;114 1146-1150

Willich SN, Maclure M, Mittleman M et al (1993). Sudden cardiac death. Support for a role
of triggering in causation. Circulation 87, (5), 1442-1450.

Sponner PM et al. (2001) Sudden cardiac death, genes and arrhythmogenesis. Circulation
103, 2361-2364.

Verrier RL, Muller JA, Hobson JA Sleep, dreams, and sudden cardiac death: The case for
sleep as an autonomic stress test for the heart. Cardiovasc Res. 31, 181-211, 1996.

Sanguinetti MC, Keating MT (1997). Role of delayed rectifier potassium channels in cardiac
repolarisation and arrhythmias. NIPS 12, (August) 152-157.

Zipes DP, Wellens H (1998). Sudden cardiac death. Circulation 98, 2334-2351.

Volders PGA., Vos MA, Szabo B et al. (2000). Progress in the understanding of cardiac early
afterdepolarisations and torsdes de pointes: Time to revise current concepts. Cardiovasc. Res.
46, 376-392.

Chiang C, Roden DM (2000). The long QT syndromes:gemetic basis and clinical
implications. J Am Coll Cardiol. 36, 1-12.

See selected articles from May issue 2001 of Cardiovascular Research that focuses on SCD.


Hot off the press
QT interval variability and cardiac norepinephrine spillover in patients with
depression and panic disorder Mathias Baumert, Gavin W. Lambert, Tye Dawood,
Elisabeth A. Lambert, MurrayD. Esler, Mariee McGrane, David Barton, and Eugene
NalivaikoAm J Physiol Heart Circ Physiol 2008;295 H962-H968
http://ajpheart.physiology.org/cgi/content/abstract/295/3/H962?etoc

Dawson, T.A., Li, D., Woodward, T.D., Barber, Z.E., Wang, L. and Paterson,
D.J. (2008) Cardiac Cholinergic NO-CGMP Signalling Following Acute
Myocardial Infarction and nNOS Gene Transfer Am. J. Physiol. Heart Circ.
Physiol. 295(3):H990-H998.
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Genetic mutations:linking Brain and Heart

Herring, N., and Paterson, D.J. (2007) Common NOS1AP Variants Are Associated
With a Prolonged QTc Interval in the Rotterdam Study Circulation 116 e564
Response to letter Aarnoudse, A-J.L.H.J., Straus, S.M.J.M., Hofman, A., Uitterlinden,
A.G., Witteman, J.C.M., and Stricker, B.H.C. (2007) Circulation 116 e565

Aarnoudse AJ, Newton-Cheh C, de Bakker PI, Straus SM, Kors JA, Hofman A,
Uitterlinden AG, Witteman JC, Stricker BH. Common NOS1AP Variants Are
Associated With a Prolonged QTc Interval in the Rotterdam Study Circulation.
2007;116:10-16.

Samuels MA. The brain-heart connection. Circulation. 2007 Jul 3;116(1):77-84. Review.


Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C,
Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE,
Marban E, O’Donnell CJ, Hirschhorn JN, Kaab S, Spooner PM, Meitinger T, Chakravarti A.
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
Nat Genet. 2006; 38: 644–651

Sudden cardiac death and stress

Li, JI, Hansen D, Mortensen PB, Olsen J (2002). Myocardial infarction in parents who lost a
child. Circulation 106, 1634-1639.

Chugh SS, Kelly KL, Titus JL (2000). Sudden cardiac death with apparently normal heart.
Circulation 102, 649-654.

Brandspiegel HZ, Marinchak RA et al. (1998). A broken heart. Circulation 98, 1349.

Leor JL, Poole WK, Kloner, RA Sudden cardiac death triggered by an earthquake. N Engl J
Med 334, (7), 1996

Mittleman MA, Maclure M, Sherwood JB et al. Triggering of acute myocardial infarction
onset by episodes of anger. Circulation 92, 1720-25, 1995.

Verrier RL, Hagestad EL & Lown B Delayed myocardial ischaemia induced by anger.
Circulation 75,249-254, 1987.


Sudden cardiac death and exercise

Siscovick DS, Weiss NS, Fletcher RH, Lasky T The incidence of primary cardiac arrest
during vigorous exercise. N Engl. J. Med. 311, 874-877; 1984.

Northcote RJ, Flanneigan C, Ballantyn, C. Sudden death and vigorous exercise - a study of 60
deaths associated with squash. Br Heart J 55: 198-203, 1986.

Tofler G.H., Stone P.H., Maclure M. et al. Analysis of possible triggers of myocardial
infarction (the MILIS study) Am Coll Cardiol. 66, 22-27. 1990
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Willich S, Lewis M, Lowel H. et al. Physical exertion as a trigger of acute myocardial
infarction. N Engl J Med 329, 1684-1690, 1993.




Autonomic imbalance and the heart

Nash MP, Thornton JM, Sears CE, Varghese A, O'Neill M, Paterson DJ (2001). Ventricular
activation during sympathetic imbalance and its computational reconstruction. J Appl Physiol
90, 287-298.

Lubbe WF, Podzuweit T, Opie LH. Potential arrhythmogenic role of cyclic adenosine
monophosphate (AMP) and cytosolic calcium overload: implications for prophylactic effects
of beta-blockers in myocardial infarction and proarrhythmic effects of phosphodiesterase
inhibitors. J Am Coll Cardiol 19: 1622-1633, 1992.

Skinner JE, Reed JC. Blockade of frontocortical-brain stem pathway prevents ventricular
firillation of ischaemic heart. Am J Physiol. 240, H156-163.

Carpeggiani C, Landisman C, Montaron MF, Skinner JE Cryoblockade in the limbic brain
(amygdala) prevents or delays ventricular fibrillation after coronary artery occlusion in
psychologically stressed pigs. Circ Res 70, 600-606, 1992.

Cardiac protection and training

Mittleman MA, Maclure M, Tofler GH, Sherwood JB, Goldberg RJ, Muller JE. Triggering
of acute myocardial infarction by heavy physical exertion: protection against triggering by
regular exertion. N Engl J. Med. 329, 1677-1683 1993.

Paffenbarger RS, Hyde RT, Wing AL, Lee I, Jung DL, Kampert JB. The association of
changes in physical activity level and other lifestyle characteristics with mortality among men.
N Engl. J Med 328, 538-545. 1993

Hull SS, Vanol, E, Adamson PB, Verrier RL, Foreman RD, Schwartz PJ. Exercise training
confers anticipatory protection from sudden death during acute myocardial ischaemia.
Circulation 89, 548-552; 1994.

Danson EJF, Paterson DJ (2003) Enhanced neuronal nitric oxide synthase expression is
central to cardiac vagal phenotype in exercise-trained mice J. Physiol. 546(1):225-232.

Treatment of SCD

Domanski MJ, Zipes DP, Schron E. (1997). Treatment of sudden cardiac death. Circulation
95, 2694-2699.




DJP
Michaelmas Term, 2008
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