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BBSRC Science and Innovation

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					 BBSRC Science and
    Innovation

    Prof. Nigel Brown
Director of Science & Technology


      Cardiff University
      27 November 2007
• Introduction to BBSRC
• CSR2007
• Grants and funding
• Knowledge Transfer and Economic
  Impact
• Q&A
Biotechnology and Biological
Sciences Research Council
MISSION
• Fund first-class bioscience research
• Train bioscientists
• Support knowledge transfer
• Engage with public

STAKEHOLDERS
• INDUSTRY: agriculture, food,
  chemical, health, pharmaceutical
• PUBLIC: dialogue and                   Why? Quality of Life
  consultation                              and UK plc
• GOVERNMENT: e.g. DEFRA, FSA,
  RCUK

     BBSRC funding totals around £380M p.a.(07/08)
“Mixed economy” of BBSRC funding

 Universities             Institutes
 • basic research         • strategic research
 • curiosity-driven       • mission-oriented
 • shorter-term funding   • longer-term funding
 • research training      • specialist facilities
Towards Predictive Biology
                Biological Sciences will be
                • more quantitative and
                  predictive and
                • more integrative in that there
                  will be
                  - input from different disciplines
                  - data from different technologies
                  - move to understand function at
                    cellular, whole animal and
                    population level
Strategic Objective 1: Excellent Science
   CSR2007

BBSRC Delivery Plan
 to be published on
 11 December 2007
   Funding – commitment 07/08

                                         KT and Innovation   Large facilities
          £387M                                [3% ]             [1% ]

                                                                      Administration
                 Institute capital                                        [3% ]
                and restructuring
                       [12% ]




                        Institute Core                                          Responsive mode
                         Grant [18% ]                                             Grants [44% ]




                     Training and
                  Fellowships [10% ]



                            Directed Initiatives
                                   [8% ]


Source – BBSRC 2004 Delivery Plan. Figures include FEC
CSR 2007: BBSRC budget allocation
             Financial year   Total Allocation
                                    (£K)
                2007-08           386,854
                2008-09           427,000
                2009-10           452,563
                2010-11           471,057


 • Second highest Research Council increase - 22%
 • Equivalent to average 4% annual increase over 3
   years set against 2.7% increase in total science
   budget
 • Good news for bioscience but much of the increase is
   for Full Economic Costing / university sustainability
 • Delivery Plan drafted for allocations
BBSRC: Headlines for CSR2007
•   Healthy Bioscience – keeping the UK biosciences
    internationally competitive and attractive to inward investment

•   Cross-Council Multidisciplinary Programmes –
    Research Councils working together across disciplines

•   Economic Impact, including Skills and Training –
    step-change in the economic impact of BBSRC‟s funding and boosting
    the supply of skilled people to the economy and society

•   National Facilities - Securing our national research capability
    and facilities in strategic areas
Healthy Bioscience

• Annual inflationary increases to responsive mode
  budget. More than £500M commitment over CSR

• Systems Biology – Maintain the high level of
  investment to embed systems approaches in UK
  bioscience base and provide requisite tools and
  resources. Approx £70M commitment over CSR

• BBSRC involvement in 5 of 6 cross-Council
  multidisciplinary programmes with around £125M
  total planned commitment. Some of delivery in RM
Multidisciplinary cross-Council Programmes

• Bioenergy
    – New Bioenergy Centre
    – Build Bioenergy research capacity in UK (plant and microbial)

• Living with Environmental Change Largely for research of relevance to
  climate change, particularly in areas of Sustainable agriculture and
  animal health.

• Ageing including
    – Increase funding for joint Centres for Lifelong Health and Wellbeing
    – Explore joint initiative with US National Institute on Aging.

• Global Threats to Security including
    – Explore animal health research for international development programme joint
      with DfID and Wellcome Trust

• Bio-nanotechnology including boost to science networks and partnerships
   with industry.
Economic Impact

 • New commitment of around £50M to deliver a step-
   change in the economic and social impact

    – at least £34m with the new Technology Strategy Board,
      where already complementary activity with Research and
      Technology Clubs (RTCs).

    – 3 RTCs already established (bioprocessing, diet and health,
      biorefineries)

    – More RTCs planned (options being considered in
      biopharmaceutical design, ageing, analysis of large data
      sets etc).

 • Skills and training - key element of long-term
   economic impact strategy
Technology Strategy Board Budget

 £1B over 3 years …

 • of which at least £120M from Research
   Councils

 • of which £34M from BBSRC
 • for complementary and collaborative activity
BBSRC Grants and Funding
BBSRC Responsive Mode Spend

               Plant and
                                          Agri-Food 11%
               Microbial
           Sciences 14%



     Genes and                                       Animal Sciences 16%
  Developmental
    Biology 16%




    Engineering and                                 Biochemistry
 Biological Systems                                 and Cell
                10%                                 Biology 17%

                           Biomolecular
                           Sciences 16%
Where does HEI funding go?
                                                                                                       Distribution by HEI and value (£M)
                                                                                   75% of the total value of grants 'live' on 1 April 2007 is directed to 18 HEIs

                                                     80



                                                     70
 Total value of grants 'live' on 1 April 2007 (£M)




                                                     60

                                                                                   25%
                                                     50


                                                                                                                                       50 %
                                                     40



                                                     30
                                                                                                                                                                                                                                               75 %


                                                     20



                                                     10



                                                     0
                                                                                                                                                               Sheffield




                                                                                                                                                                                                                                                Liverpool
                                                                                    Oxford




                                                                                                                     Glasgow


                                                                                                                               UCL




                                                                                                                                                                                                          KCL
                                                          Manchester


                                                                       Cambridge




                                                                                                                                       Edinburgh




                                                                                                                                                                                                                                 East Anglia
                                                                                                                                                                                                Bristol
                                                                                                        Nottingham




                                                                                                                                                                                   Birmingham




                                                                                                                                                                                                                          York
                                                                                                                                                                           Leeds




                                                                                                                                                                                                                Warwick
                                                                                             Imperial




                                                                                                                                                   Newcastle




                                                                                                                                     Higher Education Institution
CARDIFF UNIVERSITY


 Total value of live grants, 1st April 2007 = £11.8M

 Overall 2 yr success rate for Cardiff = 17%

 Overall HEI success rate = 26%
Grants „live‟ 1st April 2007 = £11.8M

                                  No of    Value (£k)
 Lead Department                  Grants   at 1 April
                                             2007
 School of Biosciences             22         6.1
 School of Psychology               11        2.8
 School of Medicine                 4         1.0
 School of Optometry and Vision     5         0.8
 Sciences
 Cardiff School of Chemistry        2         0.7
 Welsh School of Pharmacy           2         0.4
 TOTAL                             46        11.8
Recent changes to grants system
 • Full Economic Costing introduced
    – Resource is assessed NOT COST
 • Harmonisation of applications through Je-S
    – MRC will join in future
 • Now 4 grant rounds a year
    – Number of applications decreased
 • Longer Larger (LoLa) grant scheme
    – Outline stage for grants >£2M
 • New assessment criteria from July 2006 closing date
    – Quality of science; timeliness; economic impact
    – Appropriateness of training for staff – NEW
 • Data Sharing Policy
    – From July closing date. Extra page for DSP.
Grant funding

  • Responsive mode (investigator-led)
    – includes New Investigator and Industrial
      Partnership Awards

  • Initiatives (managed mode)
    – usually one or two calls (e.g. Systems Approaches
      to Biological Research (SABR), Bioenergy)

  • Other funding streams
    – Tools & Resources Development Fund
      (continuous)
    – Biological and Bioinformatic Resources
What makes a successful grant
application?

• Is it high quality science?
• Is it really high quality science?
• Are you absolutely sure it is high quality science?
• Is the case for support clearly written and not overloaded
  with extraneous detail?
• Have you had someone read it who is reasonably expert
  in the science?
• Can a non-specialist understand why the work is
  important?
• Have you had someone read it who doesn‟t know the area
  in detail?
What makes a successful grant
application (2)?
• Have you properly justified the resources?
• Have you indicated where it matches BBSRC priorities?
• Have you indicated the career development potential of
  the research?
• Have you got industrial partnership (IPA)?
• Have you answered the referees‟ comments robustly and
  sensibly?

• Have you received feedback on failed applications?
Closing Dates to note
 • Responsive mode
    – 22 January 2008; 23 April 2008; 22 July 2008

 • Longer Larger applications (>£2M)
    – 5 Dec 2007; 12 March 2008; 22 July 2008

 • Tools and Resources Development Fund
    – 10 January 2008

 • Follow on Fund
    – 7 February 2008; 26 June 2008


         NOTE:     closing time now 4.00 p.m.
Knowledge Transfer &
  Economic Impact
BBSRC activities to maximise
economic impact



                                Industrial
            Collaborative
                              involvement
              research
                               in training




                            Commercialisation
              People &             of
             knowledge         Research
                flow               &
                              Development
Collaborative research


•   LINK
•   TSB     Collaborative
              research
                                Industrial
                              involvement
                               in training
•   IPA
•   Clubs
                            Commercialisation
              People &             of
             knowledge         Research
                flow               &
                              Development
BBSRC technology strategy

      Identifying areas of the bioscience research base
     where an enhancement of activity may underpin the
          needs of industry over the next 10 years



 Four prime criteria:
 •   capacity for high-quality research
 •   ability of the UK science base to deliver that research
 •   size of commercial opportunity
 •   ability of companies based in the UK to derive benefit
Industrial involvement in training
People & knowledge flow

                                                • CASE
                                Industrial
            Collaborative
              research
                              involvement       • Ind
                               in training
                                                  CASE
                                                • MTI
• KTP                       Commercialisation
              People &             of
• RS-IF      knowledge         Research
                                   &
                flow
• IIP                         Development
People & knowledge flow
Industry interchange


  Interchanges between industry and academia
  (in either direction) help foster long-term
  collaborations, and offer access to knowledge,
  skills, expertise, equipment and facilities.


          Next Closing Date: 13 March 2008
Commercialisation of R&D


                              Industrial
          Collaborative
                            involvement
            research
                             in training




                                              •   YES
                          Commercialisation
            People &
           knowledge
                                 of
                             Research
                                              •   FoF
                                              •
              flow               &
                            Development           EFs
                                              •   BPC
Follow-on Fund

• to enable scientists to advance ideas with commercial
  potential to a stage where commercial opportunities can
  be secured e.g. further technical or scientific development,
  broaden patent claims, market analysis, identify licensees,
  etc.
• grants of up to £110k fEC
• open to existing grantholders
• BBSRC has funded 41 projects
  worth £3M over first five calls


Next Closing Date: 7 February 2008
The future …


• more cross-RC working
• increasing funds for collaborative research
• focus on skills
• increasing support for activities such as FoF and
  YES
• need to demonstrate economic impact
• role of new Technology Strategy Board?
Closing Dates to note

 • Responsive mode
    – 22 January 2008; 23 April 2008; 22 July 2008

 • Longer Larger applications (>£2M)
    – 5 Dec 2007; 12 March 2008; 22 July 2008
 • Tools and Resources Development Fund
    – 10 January 2008

 • Follow on Fund
    – 7 February 2008; 26 June 2008


      NOTE:     closing time now 4.00 p.m.

				
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