Pressure Sensor for Peripheral Neuropathy

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							Pressure Sensor for Peripheral
         Neuropathy

              Group 19
              Pankil Dharia
              Zachary Hafez
              Mustafa Manzoor
Agenda

   Introduction
   Objective
   Review of Design
   Functional Tests
   Successes and Challenges
   Marketing Factors
   Recommendations
   Questions
Introduction

   People who suffer from peripheral neuropathy are left
    with partial or no feeling in their limbs. They often bump
    or scrape these limbs unknowingly, which leads to
    infection and possible amputation.
   According to the Neurology Channel Online
    (http://www.cnn.com/2006/HEALTH/conditions/01/27/rar
    e.conditions/index.html), Peripheral Neuropathy affects
    at least 20 million people in the United States.
   Nearly 60% of all people with diabetes suffer from
    peripheral neuropathy
Objective

   We want to construct a product that senses when
    trauma to the foot has occurred, alerting the user of
    potential injury.
   Pressure sensors will be located on each toe, which are
    the most vulnerable to trauma in patients with
    neuropathy of the foot.
   Temperature sensors will be included to alert the user
    that their skin is in danger
   An alarm and corresponding LEDs will activate when a
    traumatic event is detected by the sensors
Design of the Product
Objective (cont.)

   Benefits:
    –   Instant notification of possible traumatic event
    –   Low cost
    –   Comfortable
    –   Adjustable
    –   Light weight and discrete
    –   Portable
    –   Commercially recreational
    –   Reduced probability of dangerous infection
    –   User friendly
Objective (cont.)

   Features:
    –   Various pressures and temperatures sensors
    –   Multiple sensor locations for distributed sensing
    –   Identification of traumatic event to assess possible damage
    –   Visual output for corresponding notifications
    –   Distinct sound output (alarm) for dangerous pressures and
        temperatures for audible notification
    –   Adjustable strap for variable location
    –   Easy to use reset button
    –   Multi-colored LEDs for differentiating causes of trauma
    –   Battery operated (+9V)
Review of Design
Review of Design
Review of Design
Power:
                1                        8
                                                              +9V
                                                       0.1u
                2                        7
                        MAX1044
                    Switched-Capacitor
                3                        6
          10u       Voltage Converter
                                                      10u
                4                        5




                                              -9V
                                             Output

   9V Battery powering entire device
   -9V produced by the above circuit
Review of Original Design
Review of Design
Pressure Sensors:
   25lb. Flexi Force Pressure Sensors(A201-25)
   Sensors placed on each digit
   The pressure exerted on the force transducer
    will vary the resistance in the sensor
   When a certain voltage threshold is reached,
    an alarm will sound with LED notification



                                      ® Tekscan
Review of Design
Temperature Sensors:
   Ametherm Thermistor (NT05-5029)
   Sensors placed on the sides of the foot
   As temp. increases, resistance decreases
   When a certain high or low threshold is reached,
    an alarm will sound with corresponding LED
    notification



                                       ® Ametherm
Review of Design
Review of Design
Operational Amplifier:

   Sensors output low voltages in millivolt range
   Operational amplifiers amplify the input
    voltage of the Flexi-force transducer by 50
    times to about 2-5 Volts
   Output signal sent to the comparator for
    further analysis
Review of Design
Review of Design
Comparator Circuit (Pressure):
   Circuit uses a comparator with Vref set to 3V
   Vref corresponds to the 5lb/(inch^2) threshold
    pressure for pain
   If input signal >= Vref
    –   Comparator outputs a logical high to the alarm system
   If input signal < Vref
    –   Comparator output will remain logically zero
Review of Design
Comparator Circuit (Temp.):
   If input temp > 50°C
       Resistance across Thermistor decreases
       Increases current and input voltage to comparator
       Triggers comparator to output logical high signal
               when input voltage >= Vref (3.12V)
   If input temp < -5°C
       Resistance across Thermistor increases
       Decreases current and input voltage to comparator
       Input voltage amplified with gain of 10
       Triggers comparator to output logical high signal
               when Vref (4.0V) >= input voltage
Review of Design
                     2K                                                      5.1K

           1                       8                              1                          8
               Rg           Rg                                        Gnd             Vcc                      +9V
           2                       7                              2                          7
               -In          +Vs        +9V                            +In           Output

           3
                 AD622AN           6                              3
                                                                            LM311N           6
               +In        Output                                      -In       Bal/Strobe

           4                       5          +9V                 4                          5
                                                     1.5K




                                                                                                 Output to System Design Block
               -Vs          REF                                       Vee             Bal

  20K

                                                            750
        FlexiForce Sensor                     -9V
                                             Block
  560




         Pressure Sensor Circuit
Review of Design                                                                               1
                                                                                                                       2K
                                                                                                                                         8
                                                                                                           Gnd                    Vcc        +9V
                                                                                               2                                         7
                                                                                                                +In            Output

                                                                                               3
                                                                                                                      LM311N             6
          +9V      5K Ohm

Temp.
                                                                                                                -In         Bal/Strobe
                                     1K
                  Thermistor
                                                                  +9V                          4                                         5
                                                                         5.2K                              Vee                    Bal




Sensor                                                                           1.1K
                                                                                         -9V
                                                                                        Block



Circuit     1
                Rg
                       2K

                               Rg
                                     8
                                                                                               1
                                                                                                                       2K
                                                                                                                                         8
                                                                                                           Gnd                    Vcc        +9V
            2                        7
                -In            +Vs
                                                                                               2                                         7
                  AD622AN                                          +9V                                          +In            Output
            3                        6                                     20K
                +In         Output
                                                                                               3
                                                                                                                      LM311N             6
                                                                                                                -In         Bal/Strobe
            4                        5
                -Vs            REF
                                                                                  1K           4                                         5
                                                                                                           Vee                    Bal

           -9V
          Block                                                                              -9V
                                                                                            Block
                                          Output to L-O-S Block




                                                                                        Output to L-O-S Block
                                                  (Cold)




                                                                                                (Hot)
Review of Design
Review of Design
Latch:
   An S/R latch (CD4043BE) is used to hold the
    signal once it has been triggered even after
    the input has been removed.
   Latch will enable the user to reset the alarm
    after being notified.
   The latch will reset the speaker alarm as well
    as the 3 LEDs.
Review of Design
Review of Design
Speaker:
   This will output a sound to alert the user of
    hazardous conditions.
   The 3 latch outputs are ORed and sent to
    the speaker
   The speaker is triggered when either latch
    (pressure, cold temp., hot temp.) is set to
    high
Review of Design
LEDs:

   Different colored LEDs are used to distinguish
    between temp. and pressure
   Red coincides to a temperature >= 50°C
   Yellow coincides to a temperature <= - 5°C
   Green coincides with a pressure >= (5lb/inch^2)
Review of Design
           +9V


                                       0
                                    Vcc1
                        1                                16
                            a1                     b1
                                                                               1                12
   Input from Inv. in   2                                15

    System Design
                            a2
                                 CD4043BE          b2
                                                                               C2               C1
   Block (pressure)     3
                            a3                     b3
                                                         14
                                                                               3                10
                        4                                13
                            a4                     b4



                        5                                12
                                                                                     Switch
                            a1                     b1                          4                 9
                        6
                            a2                     b2
                                                         11
                                                                               C4               C3
      Input from
                        7                                10                    6                 7
   Comparator Block         a3                     b3


         (Hot)          8                                9
                            a4                     b4
                                    GND
                                       0



                                                                                           Pressure
      Input from
                                                                                             LED
   Comparator Block
        (Cold)
                                                               10 K

                                                                                                 Cold Temp.
                                                                    Output                          LED




                                                                                    10 K
                                  Hot Temp.                       to System
                                                        10 K




Latch-Switch-                       LED                         Design Block
                                                                 (NOR gate)




Output Block                                   Output
                                             to System
                                           Design Block
                                                                              Output
                                                                            to System
                                                                          Design Block
                                                                           (NOR gate)
                                            (NOR gate)
Review of Design                           Input from
                                          L-S-O Block
                                                           Input from
                                                          L-S-O Block
                                                                          Input from
                                                                         L-S-O Block                 +9V


                 Amp-Comparator Block for Pressure (1)

                           Pressure
                                                                         1                           14
                                                                             a1                 b1



                                                                         2                           13
                 Amp-Comparator Block for Pressure (2)                       a2                 b2




Overall                       Sensor
                 Amp-Comparator Block for Pressure (3)
                                                                         3



                                                                         4
                                                                             a3



                                                                             a4
                                                                                  SN74LS260N
                                                                                  SN74LS260N
                                                                                                b3



                                                                                                b4
                                                                                                     12



                                                                                                     11



                                                                         5
                                                                                   NOR Gate          10



                               Circuit
                                                                             a1                 b1




System                                                                   6
                                                                             a2                 b2
                                                                                                     9




          Foot
                 Amp-Comparator Block for Pressure (4)                   7                           8
                                                                             a3                 b3


                               Blocks
Design           Amp-Comparator Block for Pressure (5)




Block              Temp. Sensor Circuit
                   Comparator Block for Temperature
                                                                                                                   +9V



                                                                                    1                          14
                                                                                        a1                b1



                                                                                    2                          13
                                                                                        a2                b2




                            L-S-O Block




                                            L-S-O Block
                                                                                    3                          12
                                                                                        a3                b3




                             Output to




                                             Output to
                                               (Cold)
                               (Hot)
                                                                                    4                          11

                                                                                         SN74ALS04BN
                                                                                        a4                b4



                                                                                    5
                                                                                        a1  Inverter      b1
                                                                                                               10




                                                          L-S-O Block
                                                           (Pressure)

                                                            Output to
                                                                                    6                          9
                                                                                        a2                b2



                                                                                    7                          8
                                                                                        a3                b3




                      Latch-Switch-Output Block




                                                                        Speaker
Functional Tests

                   Pressure
                   sensor without
                   amplification

                   Channel 1:
                   Input

                   Channel 2:
                   Output from
                   pressure
                   sensor
Functional Tests

                   Pressure
                   sensor with
                   amp. (Gain = 5)

                   Channel 1:
                   Input

                   Channel 2:
                   Output from
                   pressure
                   sensor
Functional Tests

                   Comparator
                   Circuit

                   Channel 1:
                   Input to
                   comparator

                   Channel 2:
                   Output showing
                   logical high
                   when Vref (3V)
                   is exceeded by
                   input signal
Functional Tests

                         Temp. Input With Corresponding Comparator Output


              3

            2.5

              2

            1.5
    Volts




              1                                                                            Comp. Output
                                                                                           Input
            0.5

              0

            -0.5

             -1
            -0.000006   -0.000004   -0.000002      0      0.000002   0.000004   0.000006
                                                Seconds
Functional Tests

      Oscilloscope reading of Thermistor Response
Functional Tests

   Pressure Sensor:
    –   Tested in accordance with known pressures that cause damage to foot
    –   Sensors were first aligned to the tip of each digit of subject.
    –   Tested the sensitivity of the sensors, when mapped to a specific foot.
   Temperature Sensor:
    –   Exposed to varying degrees of temp. (dry ice -20°C...flame 50°C)
   Power Supply:
    –   Voltage leaks were tested
    –   Voltages at every component were measured
   Calibration and Reliability:
    –   The pressure sensors were calibrated to injurious measurements
    –   Damaging forces were tested to ensure reliability of the circuit.
Successes and Challenges

   Successes
    –   Able to run entire device with one 9V battery
    –   After consultation with podiatrist (Dr. Reed), able
        to achieve specific thresholds
    –   Able to successfully implement a fully-functional
        model of device
Successes and Challenges
Successes and Challenges
Successes and Challenges

   Challenges
    –   Calibrating the circuit to work with precision
    –   Amplifying the signals coming from temp. and
        pressure sensors
    –   Figuring an accurate model for testing the product
    –   Using PTC-thermistors instead of NTC-thermistors
    –   Implementing device on PCB
Successes and Challenges
PCB
Successes and Challenges
PCB
Successes and Challenges
PCB
Marketing Factors
      Part                Description           Quant.   Price       Part            Description      Quantity   Price
    Battery        Connection for 9V           2          $1.00   FlexiForce    Pressure force        5            $60.00
   Connector            battery                                    A201-25      transducer (25lb)
    Speakers       Used to notify user of      1          $5.00   Thermistors   Temperature           1             $2.00
                   dangerous-pressure or                          NT05-5029     sensor with
                         temp.                                                  variable resistance
      LED          Light Emitting Diodes       3           $.50      Sock       Casing for the        1             $5.00
                   (green, red) for                                             sensors device
                   displaying signal to user
                                                                   Batteries    9V                    1             $2.00
  Operational      Amplifies voltage signal    6         $15.00
     Amplifier          from sensors                               Maxim        To generate - 9V      1             $2.00
   AD622AN                                                        Capacitor
    Latch          Used to keep alarm/LED      1           $.50
  CD4043BE         on until device is reset                          PCB        Printed circuit       1            $30.00
                                                                                      board
5-input NOR gate   Used to determine if a      1           $.50
  SN74LS260A       signal is on from the 5                         TOTAL                                         $136.00
                   pressure sensors
    Inverter       Invert output               1           $.50
   SN74LS04
 Electrical Wire   Standard wiring             5 feet    $10.00
    Resistors      Standard resistors                     $2.00
Marketing Factors

   Condense Circuit
    –   Condensing current circuit on 4-layer PCB increases
        cost
   Pressure Sensor Sheet
    –   Instead of specific points, cover entire foot
    –   PolyVinylidine DiFluoride (PVDF)
    –   Increases cost
   Reliability
    –   Decreasing false positives
    –   Safer design
Recommendations

   Programmable ICs
    –   Integrate amplifier and comparator on one IC
   PCB technique
    –   Use insulated PCBs to prevent accidental open
        circuits
   Multi-functional Speaker
    –   Be able to generate different frequency sounds
        for different signals
Relevant Ethical Issues

   Current leakage
    –   ‘Leakage Current Tests’ are run on medical related
        devices for safety
    –   How much current goes through a person’s body
        when they initially come in contact with the device until
        the current moves to ground.
    –   There usually will always be some current flow;
        however, the amount is what is measured here.
   Prevention
    –   Low current distributes throughout our circuit.
Special Thanks

   Professor Chiang Liu (University of Illinois)
   Dr. Andrew Reed
   Dr. Walid Hafez
   Dr. Raymond Fish
   ECE Parts Shop Staff
   Hyesun Park
Questions

   Any Questions?

						
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