Nail Patella Syndrome
The article nail patella syndrome gives the brief information about
glaucoma and nails patella syndrome, its causes and treatment. After
reading this article, you will be able to understand what NPS and
glaucoma is, and will be able to help yourself and other people around
Nail Patella Syndrome, Sign & symptoms of NPS, Pathological Symptoms of
Nail patella Syndrome, Musculoskeletal, Renal diseases, treatment for
Nail Patella Syndrome
Nail Patella Syndrome (NPS) is a form of rare genetic disorder. It causes
impairment of bones, joints, nails and even kidneys. An absence or
immature kneecaps and thumbnails are responsible to cause Nail Patella
Syndrome in an individual. Statistics of government agencies and
hospitals says that one in every 50000 newborn babies is affected by this
Scientists have established the close relation between glaucoma and nail
patella syndrome. At several circumstances it has been found that a
newborn affected with this rare disorder has no thumbnails or
underdeveloped thumbnails. The mother of such babies and other family
members has also found with an absence of thumbnails in most of the
medical examinations. However, it is not clear yet, whether glaucoma
directly relates to the mutation of NPS gene or it is the deficiency of a
separate gene linked with the gene of nail patella disorder.
Sign and Symptoms of Nail Patella Syndrome
General Symptoms- Some of the general symptoms of Nail Patella Syndrome
1. Low peripheral eyesight
2. Blind spots
3. Requires frequent change of spectacles
4. Blurred vision
5. Sore or red eyes or both
6. Seeing rainbows or halos around light source
7. Extreme headache, nausea and eyes pain in some of the cases
If you have any of the above symptoms, it may be because of Nail Patella
Syndrome. Go for professional medical help to fix the problem.
Pathological Symptoms- Nail Patella Syndrome (NPS) is identifiable at
two different systems, namely; Musculoskeletal and Renal.
Nails- About 80 to 90 percent cases of nail patella syndrome (NPS) show
dystrophic nails. Normally nails are found absent or deficient. Some of
the symptoms are discolored nails, kolinonychia, longitudinal ridges,
triangular lunulae. Fingernails or thumbnails are generally affected.
Knees- Knees patella closely associates with osteoarthiritis,
osteoarthrosis and the knee weekness. About in 60% cases knee patella is
either found absent or hypoplastic. An after displacement on knee flexion
some time also called knock – knee deformity can also be found.
Elbows- Deformity in elbow is not common, but aplasia, hypoplasia,
posterior process at distal ends of humerus with increased angle, limit
to extension and suppination is found in some of the cases.
Pelvis- Horns or sours can be found in llic bone and these are detectable
by X-rays only. These are pathognomic form of Nail Patella Disorder
Renal diseases are closely associates with nail patella disorder (NPS).
Studies and hospital surveys shows that about 10% patients of NPS have
renal disease. Foremost renal manifestations are: microscopic hematuria,
nephritic or minimal proteinuria, edema and hypertension.
The treatment for Nail Patella Syndrome (NPS) and glaucoma varies vastly
patient to patient. It also depends on age factors etc and the fact that
the patient is either newborn or an young person or an old age person.
Although, there is no remedy to cure the glaucoma and NPS fully, but it
can be controlled with the expert medical help. There are so many
procedures like eye drops, pills to swallow, laser techniques, and
surgery. However it is very importance to provide regular and periodic
treatment to the affected person.