Comparison of conformal dynamic arc radiotherapy

							Comparison of conformal dynamic arc radiotherapy
and intensity modulated radiotherapy
for surgically unresectable cholangiocarcinoma
: results of dosimetric study.

Researcher:       Thanarpan Peerawong, MD.
Advisor:          Assistance Professor Chonlakiet Khorprasert
Co-advisor:       1. Associate Professor Sivalee Suriyapee
                  2. Taweap Sanghangthum
                  3. Isra Israngkul Na Ayuthaya
A THESIS SUBMITTED IN PARTIAL FULFILLMENT
OF THE REQUIREMENTS FOR
THE DIPLOMA OF THAI BOARD OF THERAPEUTIC
RADIOLOGY AND ONCOLOGY
RADIOLOGY DEPARTMENT KING CHULALONGKHORN
MEMORIAL HOSPITAL

ABSTRACT

Purpose:
            To compare dose distribution of CD-arcRT and IMRT in
            conformity to the tumor and dose to organs at risk in
            surgically unresectable cholangiocarcinoma.

Methods and Materials:
            The study involved 11 cases of surgically unresectable
            cholangiocarcinoma who are simulated by computed
            tomography in the division of therapeutic radiology and
            oncology, department of Radiology, King Chulalongkorn
            Memorial Hospital during 20/9/2004 to 31/12/2005. All
            patient data was re-planned with intensity modulated
            radiotherapy technique (IMRT)and conformal dynamic arc
            radiotherapy technique(CD-arcRT). The conformation
            number and dose to critical structure was determined with
            pair t-test.
Results:
            IMRT significantly increased conformation number, means
            liver dose, V25Gy, V30Gy, V35Gy and V40Gy, dose to
            right kidney and maximum dose of spinal cord.
Conclusion:
            Both IMRT and CD-arcRT are accepted for using in
            treatment of surgically unresectable cholangiocarcinoma.
But the advantage of IMRT is more conformity and reduced
dose to critical structure when compared with CD-arcRT.