Department of Clinical Biochemistry - Download as DOC

							               Department of Clinical Biochemistry

                       Belfast Link Laboratories

The Department of Clinical Biochemistry, CPA (UK) accredited, has
Laboratories on the Belfast City Hospital, Mater Hospital and Royal Victoria
Hospital sites. A unitary management structure ensures efficiency and
compatibility across sites.
A comprehensive range of Clinical Biochemistry services are provided to
primary, secondary and tertiary healthcare in the hospitals and community
practices of most of greater Belfast. In addition, a range of more complex and
specialised Regional Services in Endocrinology (including Newborn
Screening), Paediatrics (including Inborn Errors of Metabolism), Toxicology
and Regulatory peptides are provided.
BLL Biochemistry is actively involved in basic and clinical research and
maintains close working relationships with Departments in The Queens
University Belfast and University of Ulster, to facilitate innovative research and
development. BLL has the primary Northern Ireland role in the vocational
training of all the professions within laboratory medicine – Chemical
Pathologists, Clinical Scientists and Biomedical Scientists – and participation
in the teaching of medical and science undergraduates.
BELFAST CITY HOSPITAL CLINICAL BIOCHEMISTRY LABORATORY:
Situation: Gardner Robb Building.

     1.      Useful telephone numbers:

          Hospital no.               02890 329241

          General enquiries          BCH Ext. 3096/2926/3628
          Clinical advice:           BCH Ext.3497/3136/3160 (normal working
                                     hours)
                                     BCH Ext.3216 (outside working hours)


          Key members of staff:

          Mr B Sheridan (Head of Service)
          Tel: 02890 633230
          Email: brian.sheridan@bll.n-i.nhs.uk

          Dr G P R Archbold (Consultant Chemical Pathologist)
          BCH ext 2540/2499
          Email:pooler.archbold@bll.n-i.nhs.uk

          Dr C Loughrey (Consultant Chemical Pathologist)
          BCH ext 3497/2499
          Email:clodagh.loughrey@bll.n-i.nhs.uk

          Miss E McClean (Consultant Clinical Biochemist - Toxicology)
          BCH ext 3168/3160 (direct line: 028 90263168; 028 90263160)
          Email:liz.mcclean@bll.n-i.nhs.uk

          Mrs M McDonnell (Consultant Clinical Biochemist –General
          Biochemistry and Tumour Markers)
          BCH ext 3136 (direct line: 028 90263136)
          Email:margaret.mcdonnell@bll.n-i.nhs.uk

          Mr L Tucker (Biomedical Sciences Service Manager)
          BCH ext 3194 (direct line: 028 90263194)
          Email:laurence.tucker@bll.n-i.nhs.uk

          Mr T Linton (Biomedical Scientist Grade 4)
          BCH 2697/2552
          Email:trevor.linton@bll.n-i.nhs.uk

2.        Normal working hours:

          Weekdays:                  0900 - 1730 hours

          A restricted service is provided at the weekends:
          Saturday and Sunday:       0900 - 1300 hours

          At the weekend and Bank Holidays specimens must reach the
          laboratory before 1100 hours.

          At all other times a 24 hour emergency service is available from the
          laboratory.

3.        Emergencies:

          Urgent requests must be identified using the correct ‘urgent’ label
          which is supplied by the laboratory.
          During normal working hours it is not necessary to telephone the
          laboratory to request the tests available on an urgent basis (see later).
          Tests/Profiles NOT LISTED will only be done by direct arrangement
          with the laboratory.
          Outside normal working hours on-call staff must be contacted to
          arrange emergency work before the specimen is sent to the laboratory.
          Telephone BCH, Ext.3216 or Bleep 0706.


     4.       Portering Services:

          Throughout the day the laboratory couriers do regular (hourly) pick-up
          rounds and these should be used except in the case of a genuine
          emergency when a special collection should be arranged by phoning
          BCH Ext. 2137 during normal hours or Ext. 2486 outside normal
          working hours.

     5.       Laboratory reports:

          Printed reports are delivered by courier at 1400 and 1630 hours.
          Results are also obtainable as soon as they are vetted from on-ward
          VDUs.
MATER HOSPITAL CLINICAL BIOCHEMISTRY LABORATORY:
Situation: Laboratories, Crumlin Road, Belfast

1.        Useful telephone numbers:

          Hospital no.                       02890 741211
          General enquiries /Results         MIH Ext. 2223/2229
          Clinical advice:                   MIH Ext.2326/2228 (normal working
          hours)

          Key members of staff:

          Mr B Sheridan (Head of Service)
          Tel: 02890 633230
          Email: brian.sheridan@bll.n-i.nhs.uk

          Mr L Tucker (Biomedical Sciences Service Manager)
          02890 329241 ext 3194 or 02890 633280
          Email: laurence.tucker@bll.n-i.nhs.uk

          Mr Brian Cairns (Biomedical Scientist Grade 3)
          MIH ext 2326
          Email: brian.cairns@mater.n-i.nhs.uk


2.        Normal working hours:

          Weekdays:                    0900 - 1715 hours

          A restricted service is provided at the weekends:

          Saturday and Sunday and Bank holidays: 0930 - 1230 hours

          At the weekends and Bank Holidays specimens must reach the
          laboratory before 1100 hours.

          At all other times a 24 hour emergency service is available from the
          laboratory.

     2.      Emergencies:

          During normal working hours it is necessary to telephone the laboratory
          to request the tests normally available on an urgent basis (see later). It
          is not sufficient to mark the request form urgent.

          Outside normal working hours on-call staff must be contacted to
          arrange emergency work before the specimen is sent to the
          laboratory.
          It is the responsibility of the requesting clinician to contact the
          Biomedical Scientist on-call.
      Telephone: MIH 2326 OR 2227
      Bleep : 526
      Contact Hospital switch board if person on-call cannot be
      contacted using the above.


4.    Portering Services:
Throughout the day and night specimens (except urines and group 3 Hazard
specimens) are sent to the Laboratory reception via the Hospital Pneumatic
tube system (PTS).


The PTS is available from most wards and should be used to improve total
turnaround time. The lab will return pods to the station which sent them but
does NOT hold a supply of pods. We are also not responsible for lost or
delayed pods. Please contact MAINTENANCE on Ext. 2247 if you have any
problems with the tube system.

If chute system (PTS) is not available contact general portering service via
telephone ; MIH ext 2291/2574 OR BLEEP 567/547.
ROYAL GROUP OF HOSPITALS CLINICAL BIOCHEMISTRY
LABORATORY
Situation: Kelvin Building.

  1.      Useful telephone numbers

       Hospital no. 02890 240503

       Enquires during normal working hours phone (prefix ext with
       02890 63xxxx for direct dial):
       General Biochemistry enquiries           RVH, Ext.3798
       Endocrine Biochemistry enquiries         RVH, Ext.3180
       Paediatric Biochemistry enquires         RVH, Ext.2148/3064
       Neonatal Screening                       RVH, Ext 4043
       Regional Regulatory Peptide Lab enquires RVH, Ext 2533

       Clinical advice during normal working hours phone:
       General Biochemistry                             RVH, Ext.4714
       Regional Endocrine Biochemistry                  RVH, Ext.3230
       Paediatric Biochemistry                          RVH, Ext.2148/3064
       Regional Regulatory Peptide Lab.                 RVH, Ext 2515/2737
       Neonatal Screening                               RVH, Ext 4043
       Clinical advice outside normal working hours:
       Contact Medical doctor on call either via the laboratory or via
       switchboard.

       Key members of staff:

       Mr B Sheridan (Head of Service)
       Tel: 02890 633230, RVH ext 3230
       Email: brian.sheridan@bll.n-i.nhs.uk

       Prof I Young (Consultant Chemical Pathologist)
       RVH ext 2743
       Email: i.young@qub.ac.uk

       Mr P Auld (Consultant Clinical Biochemist – General Biochemistry)
       RVH ext 4714
       Email: peter.auld@bll.n-i.nhs.uk

       Mr B Sheridan (Consultant Clinical Biochemist- Endocrinology)
       Tel: 02890 633230
       Email: brian.sheridan@bll.n-i.nhs.uk

       Dr J Ardill (Consultant Clinical Biochemist - Regional Regulatory
       Peptide Lab)
       RVH ext 2533
       Email: joy.ardill@bll.n-i.nhs.uk
          Mr L Tucker (Biomedical Sciences Service Manager)
          02890 633280 or 02890 329241 ext 3194
          Email:laurence.tucker@bll.n-i.nhs.uk

          Mr R Gamble (Biomedical Scientist Grade 4)
          RVH ext 4895
          Email: raymond.gamble@bll.n-i.nhs.uk

2.        Normal working hours:

          Weekdays      0900 - 1730 hours           All departments
          Saturday      0900 - 1300 hours           General & Endocrine
                                                    Biochemistry
          Sunday        0900 – 1300 hours           General Biochemistry

          At weekend and Bank Holidays specimens must reach the laboratory
          before 1100 hours.
          At all other times a 24 hour emergency is available from the laboratory.


     3.     Emergencies:

          In normal circumstances it is the aim of the Clinical Biochemistry
          Laboratory to process all routine profile requests within 2 hours of
          receipt in the laboratory. If results are required more urgently then the
          request MUST be arranged by telephoning the RVH Biochemistry
          laboratory, Ext. 3798. It is NOT sufficient to mark the request form
          urgent.

          Outside normal working hours on-call staff must be contacted to
          arrange emergency work before the specimen is sent to the
          laboratory. Telephone RVH, Ext.3798 or if there is no reply,
          contact the Biomedical Scientist on-call through the hospital
          telephone exchange.

     4.      Pneumatic tube system (PTS):

          Throughout the day and night specimens (except urines, samples on
          ice, blood gases and group 3 Hazard specimens) are sent to the
          biochemistry laboratory reception via the Hospital Pneumatic tube
          system (PTS).
          The pneumatic tube system is available from most wards and should
          be used to improve total turnaround time. The laboratory automatically
          returns pods to the station via a designated chip in the pod but does
          NOT hold a supply of pods. We are also not responsible for lost or
          delayed pods. Please contact dispatch on Ext. 4848 if you have any
          problems with the tube system.
5.      Laboratory reports:

     Printed reports are delivered to the wards by couriers or via PTS during
     the day. GP reports will be posted out or delivered by the specimen
     transport van drivers. Reports will contain the results of all requested
     tests and, where appropriate, the associated reference range.
     In addition, the results for both routine and emergency requests
     will be available on LabCentre at ward level as soon as they are
     validated by laboratory personnel. Please make use of this facility,
     rather than telephoning the laboratory for results.
     The laboratory will continue to contact you about unexpected abnormal
     results.
FOR ALL SITES:

1.     Completion of Biochemistry request forms:

The patient’s FULL name (an initial for the forename is inadequate), date of
birth, hospital number, source (i.e. ward/clinic/GP practice) and
consultant/GP, date and time of sample must be marked clearly on the
request form. The sample tube should be clearly identified with patient’s
forename, surname, DOB, date and time of sample. Samples that fail to meet
these criteria will be rejected e.g. inadequate patient information on form and /
or sample, no name on sample.

All specimens from known or potential carriers of Category III
pathogens, e.g. Hepatitis B, Hepatitis C or HIV must be clearly marked
with hazard labels on the request form and the specimen tube.

2.     Profiles:

Clinicians may request as many organ profiles/test groups (see below) as
required using one 4mL clotted blood sample.

Electrolyte profile         sodium, potassium, chloride, urea, CO2, creatinine.
Liver profile               bilirubin, ALP, AST, ALT, GGT, albumin.
Bone profile                calcium, phosphate, ALP, albumin.
Lipid profile               cholesterol, triglycerides, HDL, LDL

GP Profile                  sodium, potassium, chloride, urea
(NOT for hospital use)      creatinine, albumin, total protein,calcium
                            bilirubin, ALP,AST,GGT,cholesterol
3.     Tests available outside normal hours:

BCH and RVH Clinical Biochemistry        Mater Hospital Biochemistry Clinical
Laboratories:                            Laboratory:


U&E                                      U&E
LFT
Bone profile                             Bone profile
Lipid profile
Gucose                                   Glucose
Magnesium, Phosphate                     Magnesium
Calcium/albumin                          Calcium/albumin
Amylase                                  Amylase
Total and direct bilirubin               Total and direct bilirubin
Total Protein
LDH
Urate
Ammonia
Lactate
Total CK                                 Total CK
TnT
bHCG (pregnancy)
Ethanol                                  Ethanol
Paracetamol                              Paracetamol
Salicylate                               Salicylate
Digoxin                                  Digoxin (overdose only)
Theophylline                             Theophylline (overdose only)
                                         Lithium (overdose only)
                                         Iron (overdose only)
CRP                                      Neonatal CRP
CSF (TP&GLU)                             CSF
Urine and serum Osmolarity               Urine and serum Osmolarity
Random urinary electrolytes              Random urinary electrolytes
Blood gases

Several other analytes can be
measured by special arrangement
only. Please contact laboratory before
taking sample.
   3.      Forms and tubes request codes

The following tubes and request forms are obtainable only from Supplies
Stores, (Stock Requisition Book). They are not supplied by the Biochemistry
Laboratory.

        ITEM                                         CODE               UOI

        Biochemistry request form U                  WMA 3100           100
        Gel tubes - red and yellow cap               KCM295              50
        (Greiner Vacuette)
        Plain Serum Tube – red and black cap         KCM317              50
        (Greiner Vacuette)
        Blood Glucose tube – grey and black cap      KCM316              50
        (Greiner Vacuette)
        Paediatric Sample Micro Tubes                KCM108             100
        (Lithium Heparin)
        Disposable Cups 12cm                         UTC134              50
        Caps for disposable cups                     UQN110              50
        Biohazard Bag                                FSE024             100

The following sample containers will be stocked and issued by the
Biochemistry Laboratory.

        Catecholamines, Pyruvate                    Glass tube containing
                                                    preservative.
        Therapeutic Drugs                           Glass tubes.
        Trace Metals, Calcitonin, Porphyrins        Lithium Heparin tubes.
        Urinary Catecholamines, Calcium, Phosphate Urine bottle (24hr) with
                                                    preservative.
        Urinary Cortisol, Creatinine, Trace Metals, Urine bottle (24hr)
        Protein,5HIAA, 5HT
        Hypopack                                    Contains all of the
                                                    tubes required for the
                                                    investigation of
                                                    hypoglycaemia.
4. Samples sent to other CPA accreditated laboratoires for analysis.


         TEST                  HOSPITAL
 sub unit               Selly Oak Hospital
                         Birmingham
Proinsulin               Royal Surrey County
Sulphonylurea            Hospital
IGF1/IGF2 Ratio          Guilford
ACTH derivatives         Hope Hospital
                         Salford
Dihydrotestosterone      St Thomas’ Hospital
Vitamin K                London
1,25-dihydroxy vitamin   Royal Infirmary
D                        Manchester
Arginine vasopressin     Royal Victoria Infirmary
Acyl-carnitine profile   Newcastle Upon Tyne
Urine Steroid Profile    King’s College Hospital
                         London
Parathormone Related     Royal Liverpool
Peptide                  Hospital
                         Liverpool
Molar HCG                Charing Cross Hospital
Neuron Specific          London
Enolase
Inhibin B
Placental ALP
Thiopurine methyl        City Hospital
transferase (TPMT)       Birmingham
Total and Free           Sheffield Children’s
Carnitines               Hospital
Very Long Chain Fatty    Sheffield
Acids
7 Dehydrocholesterol
Trimethylamine
Carnitine
Oligosaccharides       Royal Manchester
Mucopolysaccharides    Children’s Hospital
                       Manchester
Galactokinase          Southmead Hospital
Galactose-1-Phosphate North Bristol NHS
Galactitol             Trust
                        Bristol
Carbohydrate Deficient National Hospital
Transferrrins          (UCLH Trust)
(Transferrin            London
Electrophoresis)
Purine Screen          Guy's Hospital
                       London
Jejunum Biospy         Royal Hospital for Sick
                       Children
                       Edinburgh
Steroid     Sulphatase Birmingham Children’s
Assay                  Hospital NHS Trust
                        Birmingham
Cholinesterase         St James’s University
                       Hospital,
                       Leeds
Rappamune (Sirolimus) Harefield Hospital
                       Middlesex
Samples for Medical Medical Toxicology
Toxicology Unit        Unit London
Mycophenolic Acid      St George’s Medical
                       School
                       London