CHEMISTRY _ BIOCHEMISTRY 153A _CHEM XL 153A_

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					                                CHEMISTRY & BIOCHEMISTRY 153A
                                      Summer Session A 2009

    Lectures:
    MTWRF 9:00 – 9:50 am, CS 50

    Instructor: Stacie Nakamoto, Ph.D.
            office hours: will be posted on VOH once room and schedule are coordinated
            email: chem154@live.com (write 153A in subject line)
            phone: 310-825-4472
            office: 6884 Young Hall.

    Course organization and policies:
     Description: This course focuses on the chemistry of amino acids, proteins, carbohydrates
       and lipids as well as enzyme kinetics and metabolism.

       Textbooks (any one of the following are acceptable):
        “ Fundamentals of Biochemistry,” Voet, Voet & Pratt, Wiley Publishing (recommended)
         “Biochemistry,” Voet & Voet, Third Edition, Wiley Publishing
        “Lehninger Principles of Biochemistry,” David L. Nelson & Michael M. Cox, Fourth
        Edition, 2005, Worth Publishers
        You can look up the concepts in the index of these books or any good biochemistry book.

       Chemistry 153A Compendium and Problem book, Dr. Marjorie Bates (sold at Course Reader
        Material, 1081 Westwood Blvd. (310)443-3303)

       Grading:
                   2 midterms, 100 points each   = 200 points
                   Quizzes/worksheets            = 100 points
                   Final Exam                    = 200 points
                   Total                         = 500 points

    Attendance to the discussion in which you are enrolled is required for quizzes.

    You cannot take quizzes in other sections.

    No make up quizzes or exams are given.

    Your grade will be determined by the points you earn on midterms, quizzes and a final exam. I
    will not use a “curved” scale because I want to have an atmosphere of cooperation rather than
    competition. I will use the following standard grading scale: 100 – 91 % = A; 90 – 88% = A-;
    85 – 87% = B+; 81 – 84% = B; 78 – 80% = B-; 75 – 77% = C+; 71 – 74% = C; 68 – 70% = C-;
    55 – 67% = D; below 55% = F

    NO make-up exams or quizzes are given.
    See calendar on following page for specific quiz and exam dates.
Tentative Schedule:
Date      Topic                                              Reading from
                                                             “Fundamentals” by Voet,
                                                             Voet & Pratt
June 22   Intro; Water; Buffering                            Pgs 23 - 36
June 23   Amino Acids                                        Pgs. 74 - 86
June 24   Polypeptides; Proteins                             Pgs. 125 - 140
June 25   Proteins cont, Structure & Function                Pgs. 140 - 161
June 26   Carbohydrates                                      Pgs. 219 - 242
June 29   Catch-up (if necessary)
          Amino Acids Quiz in DI (for M/W DIs)
June 30   Carbohydrates; Intro. to lipids
          Amino Acids Quiz in DI (for T/R DIs)
July 1    Lipids; Membrane Structure                         Pgs. 245 - 270
          Amino Acids Quiz in DI (for W/F DIs)
July 2    Enzymes; kinetics; kinetic plots                   Pgs. 322 – 330; 363-377
July 3    HOLIDAY
July 6    Mechanisms of enzyme catalysis                     Pgs. 330 - 347
          Carbohydrate Quiz in DI (for M/W DIs)
July 7    Enzyme regulation                                  Pgs. 347 – 360; 377-393
          Carbohydrate Quiz in DI (for T/R DIs)
July 8    Myoglobin & Hemoglobin; Preview to glycolysis      Pgs. 176 - 197
          Carbohydrate Quiz in DI (for W/F DIs)
July 9    Bioenergetics; Currencies                          Pgs. 459 - 470
July 10
          Midterm 1

          Metabolism overview                                Pgs. 449 - 459
July 13   Glycolysis Quiz in DI (for M/W DIs)
July 14   Glycolysis: Stage I, Preview of TCA cycle          Pgs.485 - 493
          Glycolysis Quiz in DI (for T/R DIs)
July 15   Glycolysis: Stage I & II                           Pgs. 494 – 505; 510 - 515
          Glycolysis Quiz in DI (for W/F DIs)
July 16   Glycolysis, Gluconeogensis; Fermentation           Pgs. 505 – 510; 552 - 556
July 17   Multienzyme complexes; Pyruvate Dhase Complex      Pgs. 570 - 576
July 20   Pyruvate Dhase Complex; TCA cycle                  Pgs. 566 – 570
July 21   TCA Cycle                                          Pgs. 576 - 594
July 22   Electron Transport & Electron Shuttle              Pgs. 596 - 602
July 23   Reduction Potentials, Electron Transport           Pgs. 470 - 474
July 24
          Midterm 2

          Electron Transport; Photosynthesis                 Pgs. 604 – 618; 640 - 652
July 27   TCA Quiz in DI (for M/W DIs)
July 28   Ox-Phos; Big Picture                               Pgs. 618- 634
          TCA Quiz in DI (for T/R DIs)
July 29
          TCA Quiz in DI (for W/F DIs)
July 30   Q&A
July 31
          Final Exam, 9-11:30am – room(s) to be announced.

				
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