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Curcumin an Effective Anticancer Agent

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Curcumin an Effective Anticancer Agent Powered By Docstoc
					                                                    Presented by Daniel Toriola


       Curcumin, the natural pigment that gives the curry spice turmeric its yellow color, has developed quite an
                                impressive reputation for it ability to boost immunity.
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                                               Curcumin an Effective Anticancer Agent
                                                                   By Avon Howard



   Turmeric (Curcuma longa), a member of the ginger family, is a traditional Indian curry spice. It is
also used as a yellow food coloring and has been used in traditional medicine. Curcumin has been
used for thousands of years as a safe anti-inflammatory in a variety of ailments as part of Indian
traditional medicine. Curcumin is water soluble Curcumin have the potential for the development of
modern medicine for the treatment of various diseases.

Curcumin, a substance found in the spice turmeric, has long been used in Asian medicine to treat
maladies ranging from heartburn to arthritis. Now some recent research suggests that Curcumin may
help prevent or treat cancer. Its anticancer effect is mainly mediated through induction of apoptosis. In
a wide range of cancer cells, Curcumin has been shown to induce cell shrinkage, chromatin
condensation, DNA fragmentation and block cellular signal transduction, all of which are characteristics
of apoptosis. Curcuminoids are capable of both preventing free radical formation, as well as
neutralizing existing free radicals, and are considered an effective bioprotectant due to this dual
activity.
In cancer research, Curcumin is known as "interrupting the cell cycle." Curcumin can stop cancer in its
earliest stages, long before it's detectable. It works at the level of the cell. One of the things it does is to
tell damaged cells to self-destruct so they won't keep multiplying. Curcumin does not induce apoptosis
of healthy cells, only cancerous ones. It identifies cancer cells by their abnormal chemistry. Curcumin
increases the production of proteins that cause immune cells to proliferate and reduces the production
of proteins that destroy immune cells.
Curcumin is thought to have antioxidant properties, which means it may decrease swelling and
inflammation. It's being explored as a cancer treatment because inflammation appears to play a role in
cancer. The immune system of patients with advanced cancer is significantly weakened, mostly
because the main cells that fight off tumors either cannot proliferate anymore or have died off.
Curcumin was shown to have anti-tumor activity. Curcumin has been studied for use in treating or
preventing colon, skin and breast cancers.
Grenera Nutrient is an integrated Company that deals with managing the turmeric fields to the
production of value added Curcumin products. For further information and purchase of Curcumin
products visit http://www.greneracurcumin.com


Avon Howard Jr. is a nutrition consultant and has been involved with the health food industry for more
than 2 decades. . He is a part of many research teams that has worked on the impact of various herbal

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                                  Could Getting Spicy Aid Your Treatment Of Cancer
                                                              By Rusty Ford



 Wow, as a two time survivor of cancer I found it amazing that I might be able to eat my self free of
cancer. Well, that is an over statement but new research is showing that Curcumin to have strong
cancer fighting properties. Curcumin also called turmeric is the compound that gives curry its yellow
tint. Curcumin has long been known for its antioxidant properties and is being studied now for it
benefits in treating several different diseases. Cancer researchers have taken an interest in Curcumin
because many countries with curry-rich cuisines have lower cancer rates than Western countries have.


Researchers from the University of Texas M. D. Anderson Cancer Center found Curcumin, blocks a
key biological pathway needed for development of melanoma and other cancers. The study was
published in the August 15, 2005 issue of the American Cancer Society journal "Cancer". The study
tested varying doses of Curcumin on three melanoma cell lines. It showed that Curcumin stops
laboratory strains of melanoma from proliferating and induced apoptosis (programmed cell suicide).
The results were the same for high concentrations of Curcumin over short periods of time and smaller
doses over longer periods of time.

In a study published in 2002 in "Cancer Epidemiology, Biomarkers & Prevention", researcher gave
three groups of mice different amounts of Curcumin extract for 15 weeks. The results showed that the
group of mice given the largest amount of Curcumin found a reduction of 40 percent in benign tumors
that were caused the same gene that causes mot types of colon cancer. A similar study was published
in "The Prostate" in 2001. Again three groups of mice were used. All three were injected with human
prostate cancer cells. One group was a placebo group that received no treatment. One group was
given Curcumin when injected with the cancer cells. The other group was given Curcumin two weeks
after the cancer injection. After 6 weeks the tumors in the two groups give Curcumin were to percent
smaller than in the placebo groups.

A study on Curcumin and breast cancer was published in Cancer Research, Vol. 62, July 1, 2002, pp.
3868-75. This study found that the use of Curcumin was as effective in preventing the spread of breast
cancer as Taxol in laboratory mice. In the study mice were induced with breast cancer then the tumors
were removed such as with a mastectomy in humans. Then the mice were divided into 4 groups. One
was a placebo group, one received Curcumin, one received Taxol, and the other Curcumin and Taxol.
After 5 weeks the study showed that half the mice in the Curcumin group had the cancer spread to the
lungs. Only 22 percent of those in the Curcumin plus Taxol group had seen the cancer spread. 75
percent of the Taxol only group saw the cancer spread. The placebo group saw 95 percent of the mice
had the cancer spread to the lungs. These were amazing results.

Human studies are just beginning. But the early signs are that the simple safe spice may offer a safe
way of preventing cancer and may also be a great way of aiding in the treatment of Cancer.

It should be noted that a culture study showed that Curcumin reduced the effects of several chemo
drugs used for treating cancer.

Rusty Ford http://my-local-news.com



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Rusty Ford is the editory of http://arthritis-symptom.com and the health editor for
http://My-Local-News.com.




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