How to write a successful Grant

How to write a successful Grant Nancy Kiviat Grant writing   What to do to learn to write a grant Is there a recipe for a successful grant Past grant experience  Grants written and funded: – Molecular epidemiology   Cancer Infection – – – Molecular Pathogenesis Biomarker discovery HIV Immunology Cancer epidemiology Infection epidemiology AIDS Molecular pathogenesis  Study sections – – – – How to learn to write a successful grant    Should be part of fellowship program Help write grants in your research group When you are ready to write a grant – – – – – Find a mentor Not necessarily someone you work Someone with a good track record Someone who will commit to meeting with you Read their old funded grants   Get on grant review panels Don’t get discouraged when your critiques come back and you need to make changes – – Successful grant writers always think they not the reviewing committee is correct But they always make suggested changes (with a smile)  Grant reviews are both instructive and a “crap shoot” Most important issues to address when writing a grant     Propose to address a question that is important with an intriguing hypothesis Provide appropriate (a little but not too much) preliminary data Have, or collaborate with people with, a relevant track record Know the grant writing formula: – – Bad grants are terrible in many different ways Good grants all have certain things in common Address an important question with an intriguing hypothesis  Spend several weeks thinking about what the question and the hypothesis is – – Question must be “hot”, important, novel. Hypothesis must be really interesting  Talk about aims and hypotheses with a variety of people Provide appropriate preliminary data  At least one of the collaborators on the grant must have some preliminary data relevant track record  Examples: – – – – T regulatory cells Collect biopsies from HIV infected persons Enroll and follow 500 people Develop new assays  collaborate Know the grant writing formula:  Well written easy to understand – Ask someone not in the field or even science to read the aims background and significance   Abbreviations, tables, figures First page: preamble and aims – The “red light” test First page: preamble and aims   Set the stage Paragraph #1: – – We are proposing …. The importance of the proposed study is…. We hypothesize… We propose Closing line summarizing importance  Paragraph #2: – – –  Aims Recipe for writing a successful grant  Keep in mind the criteria that will be used to review your grant: – – – – – Significance: (important health problem) Approach: (study design) Innovation: Investigators: Environment

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