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Reference to the calculation in the sheets "Calculation details" and "Constants":
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How to do
This tool can calculate effect factors from individually supplied data
Enter data for your first substance in the sheet "Input" in the cells B2 to B21. You can enter data for additional
substances in the collumns C to K. You can enter data for up to 10 substances. The present data are for
demonstration purposes and can be over written.
Notice the number (1 to 10) in the first row of the substance you want to calculate.
Go to the sheet "Results" and write this number in the cell A1. The results are presented in columns B to E
You can check the calculations in the sheet "Calculation details"
The results are presented in the sheet "Results"
Constants applied by the calculation are shown in the sheet "Constants"
Reference to the calculation in the sheets "Calculation details" and "Constants":
Wenzel, H., Hauschild, M. and Alting, L. (1997) Environmental Assessment of Products. Volume 1: Methodology, tools and case studies in
product development . Chapmann & Hall
Hauschild, M and Wenzel, H. (1998) Environmental Assessment of Products. Volume 2: Scientific background. Chapmann & Hall
A B C D E F G H I
1 No 1 2 3 4 5 6 7 8
2 CAS No 104-76-7 75-56-9 5329-14-6 75-07-0 64-19-7
3 Name 2-Ethyl hexanol 1,2-Propylene oxide Sulphamic acidAcetaldehyde Acetic acid
Human Toxicity Oral
4 [mg/kg body] 1,628 1,100 3160 4800 306
Human Toxicity by Air
5 [mg/m3 air] 11,000 273 0.1
Ecotoxicity data acute
6 [mg/m3 water] 7,500 100,000 14200 10000
Ecotoxicity data chronic
7 [mg/m3 water] 7,500 100,000 14200 10000
8
9 AFhuman oral 10,000 100,000 100000 10000 1000
10 AFhuman air 100,000 1000 1
11 AFecotox acute 10 10 100 2
12 AFecotox chronic 100 100 1000 20
13
14 Kd (NOT USED)
AHL, Half life air OH
reaction (days) 12 hrs
15 day, 1,5E6 OH/cm3 0.81 17.87 76.4 0.63 17.2
H, Henry's law konstant
16 (atm*m3/mole, 25 0C) 4.66E-05 1.23E-04 1.00E-99 6.00E-05 2.90E-07
Log Kow, Kow is the
octanol water partitioning
17 coefficient 2.73 0.03 -4.34 -0.34 -1.6 1.15 -0.17
18
19 BIO, Biodegradbility 0.2 1 0.2 0.2 0.2
Koc Coefficient of
adsorption for
substances in soil
expressed for organic
20 fraction of soil 26 2.324 6.12 1.5 193 25.5 1
BCF, Bio Concentration
21 Factor 62 3.162 3.162 1.533
22 pKa (optional)
23
J K L
1 9 10
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7 64-19-7
Acetic acid
Human Toxicity
EF(hta) by emission to air m3 air/g 1.00E+04
EF(htw) by emission to air m3 water/g 3.28E-06
EF(hts) by emission to air m3 soil/g 1.47E-03
EF(hta) by emission to water m3 air/g 0.00E+00
EF(htw) by emission to water m3 water/g 1.64E-05
EF(hts) by emission to water m3 soil/g 0.00E+00
EF(hta) by emission to soil m3 air/g 0.00E+00
EF(htw) by emission to soil m3 water/g 0.00E+00
EF(hts) by emission to soil m3 soil/g 1.84E-03
Ecotoxicity
EF(etwc) by emission to air m3 water/g 8.00E-02
EF(etsc) by emission to air m3 soil/g 7.36E-01
EF(etwc) by emission to water m3 water/g 4.00E-01
EF(etwa) by emission to water m3 water/g 2.00E-01
EF(etsc) by emission to water m3 soil/g 0.00E+00
EF(etwc) by emission to soil m3 water/g 0.00E+00
EF(etsc) by emission to soil m3 soil/g 9.20E-01
Write the number of the substance in the cell A1
A B C D E F
1 Parameters for calculating effect factors for toxixcity
2 Symbol Parameter Unit 7 Ref.
3 CAS No CAS Number - 64-19-7
4 Name Substance Name - Acetic acid
Human Tox oral, Lowest
relevant and reliable human
5 HTo toxicity data found, oral admin. mg / kg body weight 306
Lowest relevant and reliable
human toxicity data found,
6 HTa inhalation admin. mg/m3 0
7 ETa Data for ecotoxicity acute mg / m3 water 10,000
8 ETc Data for ecotoxicity chronic mg / m3 water 10,000
Assessment factor for oral
9 AFho exposure, human - 1,000 [2], p 390
Assessment factor for
10 AFha exposure by air, human - 1 [2], p 390
Assessment factor for
11 AFeta ecotoxicity acute - 2 [2], p 256
Assessment factor for
12 AFetc ecotoxicity chronic - 20 [2], p 253
Assessmenmt factor for effect
on aerobic heterothrophic
13 AFaerob bact bacteria - 0 [2], p 264
14 Kd Coefficient of adsorption in soil - 2.00E-02 [2], p 374
That part of the emission
which contribute to toxicity via
15 fw (via air) surface water - 0.2 [1], p 285
That part of the emission
which contribute to toxicity via
16 fs (via air) soil - 0.8 [1], p 285
That part of the emission
which contribute to toxicity via
17 fw (via water) surface water - 1 [1], p 286
That part of the emission
which contribute to toxicity via
18 fa (via water) air - 0 [1], p 286
That part of the emission
which contribute to toxicity via
19 fs (via water) soil - 0 [1], p 286
That part of the emission
which contribute to toxicity via
20 fw (via soil) surface water - 0 [1], p 287
That part of the emission
which contribute to toxicity via
21 fa (via soil) air - 0 [1], p 287
That part of the emission
which contribute to toxicity via
22 fs (via soil) soil - 1 [1], p 287
That part of the emission
which contribute to acute
23 fwa (via air) ecotoxicity in water - 0 [1], p 265
That part of the emission
which contribute to chronic
24 fwc (via air) ecotoxicity in water - 0.2 [1], p 265
A B C D E F
2 Symbol Parameter Unit 7 Ref.
That part of the emission
which contribute to chronic
25 fsc (via air) ecotoxicity in soil - 0.8 [1], p 265
That part of the emission
which contribute to acute
26 fwa (via water) ecotoxicity in water - 1 [1], p 266
That part of the emission
which contribute to chronic
27 fwc (via water) ecotoxicity in water - 1 [1], p 266
That part of the emission
which contribute to chronic
28 fsc (via water) ecotoxicity in soil - 0 [1], p 266
That part of the emission
which contribute to acute
29 fwa (via soil) ecotoxicity in water - 0 [1], p 267
That part of the emission
which contribute to chronic
30 fwc (via soil) ecotoxicity in water - 0 [1], p 267
That part of the emission
which contribute to chronic
31 fsc (via soil) ecotoxicity in soil - 1 [1], p 267
Biotransfer factor from soil
32 Bb and food to meat in cattle 1.69824E-08 [2], p 381
Biotransfer factor from soil
33 Bm and food to milk in cattle 5.37032E-09 [2], p 383
Transfer factor from soil,
34 Ts,p plants - 4.54E-01 [2], p 367
35 Ts,b Transfer factor from soil, beef 1.37E-07 [2], p 381
36 Ts,m Transfer factor from soil, milk 4.34E-08 [2], p 383
37 Is*Ts Total from soil 4.22E-03 -
38 SCF Stem Concentration Factor - 1.30E-01 [2], p 374
Transfer factor from water (=
39 Tw BCF) - 0.067608298 [1], p289
40 HRD Human Reference Dose mg / kg body weight / day 3.06E-01 [1], p 295
Human Reference
Concentration (HRC kan
beregnes fra HRD se side 390
41 HRC i Sci Back..) mg/m3 air 1.00E-01 [1], p 294
The highest concentration
assessed not produce acute
ecotoxic effects in the water
42 PNECwa compartment g / m3 water 5.00E+00 [1], p 271
The highest concentration
assessed not produce chronic
ecotoxic effects in the water
43 PNECwc compartment g / m3 water 5.00E-01 [1], p 269
The highest concentration
assessed not produce chronic
ecotoxic effects in the soil
44 PNECsc compartment g / m3 water 2.18E-01 [1], p 272
Human Toxicity Factor for
45 HTFa exposure via air m3 air/g 1.00E+04 [1], p 294
Human Toxicity Factor for
46 HTFw exposure via surface water kg body weight / mg 3.27E+00 [1], p 294
A B C D E F
2 Symbol Parameter Unit 7 Ref.
Human Toxicity Factor for
47 HTFs exposure via soil kg body weight / mg 3.27E+00 [1], p 294
Ecotoxicity Factor for acute
3
48 ETFwa effects in water m water/g 2.00E-01 [1], p 268
Ecotoxicity Factor for chronic
49 ETFwc effects in water m3 water/g 2.00E+00 [1], p 268
Ecotoxicity Factor for chronic
3
50 ETFsc effects in soil m soil/g 4.60E+00 [1], p 268
51
52 Human Toxicity
EF(hta) by emission
53 to air m3 air/g 1.00E+04 [1], p 296
EF(htw) by emission
3
54 to air m water/g 3.28E-06 [1], p 296
EF(hts) by emission
3
55 to air m soil/g 1.47E-03 [1], p 296
56
EF(hta) by emission
57 to water m3 air/g 0.00E+00 [1], p 296
EF(htw) by emission
3
58 to water m water/g 1.64E-05 [1], p 296
EF(hts) by emission
3
59 to water m soil/g 0.00E+00 [1], p 296
60
EF(hta) by emission
61 to soil m3 air/g 0.00E+00 [1], p 296
EF(htw) by emission
3
62 to soil m water/g 0.00E+00 [1], p 296
EF(hts) by emission
3
63 to soil m soil/g 1.84E-03 [1], p 296
64 Ecotoxicity
EF(etwc) by emission
65 to air m3 water/g 8.00E-02 [1], p 275
EF(etsc) by emission
3
66 to air m soil/g 7.36E-01 [1], p 275
67
EF(etwc) by emission
68 to water m3 water/g 4.00E-01 [1], p 275
EF(etwa) by
69 emission to water m3 water/g 2.00E-01 [1], p 275
EF(etsc) by emission
70 to water m3 soil/g 0.00E+00 [1], p 275
71
EF(etwc) by emission
72 to soil m3 water/g 0.00E+00 [1], p 275
EF(etsc) by emission
73 to soil m3 soil/g 9.20E-01 [1], p 275
74
75
76
77 AHL Atmospheric half life days 17.2
78 H Henry's Law Constant atm*m3/mol 2.90E-07
Kow is the octanol water
partitioning coefficient (KOW =
79 Log Kow POW) - -0.17
80 BIO not relevant BIO degradeability 0
81 BIO BIO degradeability factor - 0.2
A B C D E F
2 Symbol Parameter Unit 7 Ref.
Coefficient of adsorption for
substances in soil expressed
82 Koc for organic fraction of soil 1
Bio Concentration Factor (Kan
beregnes udfra Log Kow Se
83 BCF side 369 Sci Back..) kg water / kg fish 0.067608298
84 pKa Acid constant
A B C D E
1 Constants applied in the calculations
2 Symbol Parameter Unit Value Ref
3 a Ratio of distribution between water and soil - 0.2 [1], p 284
4 fa (via air) That part of the emission which contribute to toxicity via air - 1 [1], p 285
That part of the emission which contribute to acute ecotoxicity in
5 fwa (via soil) water - 0 [1], p 267
That part of the emission which contribute to acute ecotoxicity in
6 fwa (via air) water - 0 [1], p 265
7 Ia Intake factor for air - 1 [2], p 367
8 Ta Transfer factor from air - 1 [2], p 367
9 Ts,d Transfer factor from soil, direct - 1 [2], p 367
10 Iw Intake factor for water kg fish / kg body weight / day 3.71E-04 [2], p 367
11 Is,p Intake factor for soil via plants kg plant / kg body weight / day 9.30E-03 [2], p 367
12 Is,d Intake factor for soil, direct kg soil / kg body weight / day 2.86E-06 [2], p 367
13 Is,b Intake factor for soil, via beef kg beef / kg body weight / day 1.53E-03 [2], p 367
14 Is,m Intake factor for soil, via milk kg milk / kg body weight / day 1.32E-02 [2], p 367
15 foc Relative content of organic carbon (g/g) kg/kg 0.02 [2], p 374
*
16 d Density of soil kg/l 1.5 [2], p 373
17 fw* Water content of soil l/l 0.4 [2], p 373
18 CF Factor to convert from g to mg (or m3 to liter) mg/g 1000 -
19 Wh Bodyweight of an average person kg 70 [2], p 391
20 Vh Volume inhaled daily m3 20 [2], p 391
That part of the emission which contribute to acute ecotoxicity in
21 fwa (via water) water - 1 [1], p 267
22 AFp Default assessment factor for calculating ETFp - 5
23 BIs Daily ingestion of soil for cattle kg 0.41 [2], p 381
A B C D E
24 BIp Daily ingestion of plants for cattle kg 16.9 [2], p 381
