; Ohio Cancer Data
Documents
Resources
Learning Center
Upload
Plans & pricing Sign in
Sign Out
Your Federal Quarterly Tax Payments are due April 15th Get Help Now >>

Ohio Cancer Data

VIEWS: 126 PAGES: 39

  • pg 1
									Analysis of Cancer Data in Ohio :
Colon Rectum and Anus, Lung and Bronchus, and Stomach Cancer

Sehee Kim : kim102@stat.purdue.edu Eunjung Lim : lime@stat.prudue.edu Kyung-Mi Park : park67@stat.purdue.edu Suk-Young Yoo : yoo@stat.purdue.edu

About Ohio State:
   

Capital: Columbus Number of counties: 88 5 largest cities (2003 est.): Columbus, Cleveland, Cincinnati, Toledo, Akron Geography: - midwestern state in the Great Lakes region of the United States. - bordered by Pennsylvania (NE) West Virginia (SE), Kentucky (S), Indiana (W), and Michigan and Lake Erie (N) - situated on the great inland waterways and crisscrossed by the interstate roadway system - fairly flat, with some rolling country and, in the southeast, small rugged hills leading to the mountains of West Virginia.

Ohio and USA
Ohio Population 11,435,798 USA 290,809,777

White persons
Smoking rate Median value of owner-occupied housing units Household income Land area

85.0%
27.7% $103,700 $40,956 40,948

75.1%
22.1% $119,600 $41,994 3,537,438

The Structure of Ohio’s Economy


Mainstay: commerce and manufacturing - Leading industries: plastics, rubber, electrical equipment, appliances steel, and motor vehicle. - Other sectors: food processing Industry, Information Industry

Ohio Cancer

Ohio Cancer

Colon Rectum and Anus Cancer
  

The colon and rectum are part of the digestive tract The third most common type of cancer in both men and women in the United States 145,000 cases of colorectal cancer will be diagnosed and about 56,000 people will die from the disease in 2005.

Colon Rectum and Anus Cancer

Colon Rectum and Anus

Colon Rectum and Anus Cancer
 



White Population Total : 9,834,695 Total Cases - Male : 15,050 - Female : 15,345 Cancer Rate - Male : 0.3% - Female : 0.31%

Colon Rectum and Anus Cancer: Male
Moran’s I Univariate EB rate Pearson 0.1646 0.1689 0.1261 Mean -0.0101 -0.0117 -0.0094 Std 0.0554 0.0684 0.0629 P-value 0.0082 0.0060 0.0197

Colon Rectum and Anus Cancer: Female
Moran’s I Univariate EB rate Pearson 0.1703 0.1604 0.0760 Mean -0.0105 -0.0115 -0.0116 Std 0.0547 0.0555 0.0620 P-value 0.0068 0.0065 0.0890

Common area for Colon Rectum and Anus Cancer : Male
County Name Belmont Guernsey Harrison Jefferson Hot Spot Monroe Morgan Muskingum Noble Washington Counts 158 68 37 159 29 25 142 23 124 Population 33349 19638 7650 34171 7493 6976 39719 6505 30782 Rate(%) 0.473777 0.346267 0.483660 0.465307 0.387028 0.358372 0.357512 0.353574 0.402833

Common area for Colon Rectum and Anus Cancer : Female
County Name Belmont Counts 149 Population 33349 Rate(%) 0.44679

Guernsey
Hot Spot Monroe

78
39

19638
7493

0.39719
0.52049

Morgan
Muskingum Washington

22
152 105

6976
39719 30782

0.31537
0.38269 0.34111

Colon Rectum and Anus Cancer: Conclusion
 

Clustered area is mountain area. The percentage of persons 65 years old and over is relatively higher than average in Ohio (U.S. Census Bureau).

Lung and Bronchus Cancer in Ohio




Cancers of the lung and bronchus make up the greatest percentage of incident cancers reported, comprising 16.3 % of incident cancers in Ohio in 1996-2000 (Table 1). The average annual age-adjusted lung and bronchus cancer incident rate was 75.5 cases per 100,000 residents, which is about 21 percent higher than the average annual age-adjusted U.S. incidence rate 62.6 cases per 100,000 residents.

Figures of Lung and Bronchus Cancer

Quantile Plots by Rate and Pearson Residual of Lung and Bronchus Cancer: Male

Global and Local tests for Lung and Bronchus Cancer : Male
Moran’s I Univariate EB rate Pearson 0.1735 0.1730 0.1381 E(I) -0.0110 -0.0110 -0.0110 Mean -0.0119 -0.0157 -0.0111 Std 0.0636 0.0864 0.0611 P-value 0.0030 0.0190 0.0140

Cluster plots by SatScan and consistent clusters for Lung Cancer : Male


Cool spot Hot spot

Hot spot : Jefferson, Belmont, Harrison Cool spot : Wayne, Ashland, Knox, Mercer, Madison, Franklin

Cool spot Cool spot



Common area for Lung and Bronchus Cancer : Male
County Name Hot Spot Jefferson Harrison Belmont Wayne Cool Spot Ashland Knox Franklin Mercer Mean Total Counts 283 59 230 212 101 104 1545 59 22956 Population 34171 7650 33349 53839 25616 26613 403426 20143 4917348 Rate (%) 0.8282 0.7712 0.6897 0.3938 0.3943 0.3908 0.3830 0.2929 0.4668

Quantile Plots by Rate and Pearson Residual of Lung and Bronchus Cancer: Female

Global and Local tests for Lung and Bronchus Cancer: Female
Moran’s I Univariate EB rate Pearson 0.0827 0.1019 0.1680 E(I) -0.0110 -0.0110 -0.0110 Mean -0.0125 0.1688 -0.0062 Std 0.0620 0.0683 0.0637 P-value 0.0620 0.8380 0.0060

Cluster plots by SatScan and consistent clusters for Lung Cancer : Female

Cool spot

Cool spot

Cool spot: Van Wert, Putnam, Mercer, Marion, Ashland


Cool spot

Common area for Lung and Bronchus Cancer: Female

County Name Putnam Cool spot Van Wert Mercer

Counts 18 22 45

Population 16713 53839 20143

Rate (%) 0.1077 0.1523 0.2234

Ashland
Marion Mean Total

63
84 16937

25616
30494 4917348

0.2459
0.2755 0.3444

Summary: Lung and Bronchus Cancer
 

For male case: Every global test implies the indication of a cluster for lung cancer. The consistent areas by LISA, LISA with EB rate, and Satscan are :
- Hot spot: Jefferson, Belmont, Harrison - Cool spot: Wayne, Ashland, Knox, Mercer, Madison, Franklin



For female case: Only Moran’s I with Pearson residual test is significant and other tests are not significant.

Stomach Cancer


Risk factors - the gene inheritance - over the age of 55 - intake of large amounts of smoked foods, salted fish and meat, foods high in starch and low in fiber, and pickled vegetables, - heavy smoking and drinking (2 or more drinks a day) - previous stomach surgery



The total 3264 cases are reported with 0.000664% in Ohio
- Male : 2,006 cases (0.00041% ) - Female : 1,258 cases (0.000256% )

Figures of Stomach Cancer

Global tests for Stomach Cancer: Male
Moran’s I Univariate EB rate Pearson 0.1732 0.2282 0.2407 E(I) -0.0110 0.0110 -0.0109 Mean -0.0088 0.0604 0.0036 Std 0.0625 0.0486 4.1419 P-value 0.007 0.001 0.001

Local tests for Stomach Cancer: Male
Hot spot : Turmbull,
Portage, Columbiana, Caroll, Harrison, Belmont (adding Mahoning and Stark for LISA with EB)

Cool spot : Licking,
Fairfield, Perry, Hocking, Athens, Washington (adding Delaware and Franklin and dropping Washington for LISA with EB)

SatScan Clusters for Stomach Cancer: Male

Common Areas for Stomach Cancer : Male
County Name
Trumbull Portage

Counts
55 30 22 8 4 13 14 14 1 3 6 9

Population
101542 71773 54036 14158 7650 33349 69574 58402 16792 13174 29083 30782

Rate (%)
0.05416 0.04180 0.04071 0.05651 0.05229 0.03898 0.02012 0.02397 0.00596 0.02178 0.02063 0.02924

Hot Spot

Columbiana Carroll Harrison Belmont Licking Fairfield

Cool Spot

Perry Hocking Athens Washington

Global tests for Stomach Cancer: Female
Moran’s I Univariate EB rate Pearson 0.0932 0.1519 0.1232 E(I) -0.0110 -0.0110 -0.0109 Mean -0.0114 0.0775 0.0035 Std 0.0646 0.0505 2.2597 P-value 0.050 0.073 0.019

Local tests for Stomach Cancer: Female

Hot spot : Lake Cool spot : Coshocton,
Holmes, Muskingum, Morgan, Knox, licking, Perry, Delaware, and Franklin

SatScan Clusters for Stomach Cancer: Female

Common Areas for Stomach Cancer : Female
County Name Hot Spot
Lake

Counts
43 1 10 0 4 83 1

Population
108521 17843 69574 16991 51832 403426 19282

Rate (%)
0.03962 0.00560 0.01437 0 0.00772 0.02057 0.00519

Coshocton

Licking
Perry Delaware Cool Spot Franklin Holmes

Muskingum
Morgan Knox

7
0 0

39791
6979 26613

0.01762
0 0

Common Areas for Stomach Cancer : Male and Female

Summary for Stomach Cancer
  


 

Hot spot in the eastern area (for male ) Cool spot in the middle area (for male and female) There is only one county of hot spot for female. The increment of stomach cancer is very low. The eastern area may share similar diet habit. Also the percentage of 65 years old and over in eastern area is relatively higher than the average in Ohio.

Conclusion
Our Cancer clusters are concentrated in the area of Appalachian mountains: - older, poorer, lower levels of education, more uninsured, poorer overall health status, and high prevalence of risk factors for cancer (tobacco use, high fat diet, and physical inactivity )



								
To top