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Expression profiling of human islets

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					Supplemental Table 1. mRNA expression levels of voltage gated ion channels in human pancreatic islets
Gene ID Protein ID Expression level (AU) ± SE (n=4) 0 58 ± 15 73 ± 10 68 ± 30 8±2 2500 ± 530 1400 ± 270 0 27 ± 10 19500 ± 900 25 ± 15 3900 ± 670 830 ± 210 980 ± 230 600 ± 190 380 ± 100 5500 ± 1100 0 20 ± 10 130 ± 50 10400 ± 1900 630 ± 150 21000 ± 5500 50 ± 30 5800 ± 610 1500 ± 240 720 ± 260 1300 ± 330 3300 ± 770 230 ± 60 7±3 24 ± 6 0 0 8±3 0 0 5±1 0 Fraction 1 (%) 0 1 2 2 0 60 35 0 1 80 0 16 3 5 3 2 29 0 0 1 56 3 N.A. 1 72 18 9 26 68 5 0 0 0 0 0 0 0 0 0

Voltage gated Na+-channel, α-subunit

SCN1A SCN2A SCN3A SCN4A SCN5A SNC8A SCN9A SCN10A SCN11A
Na+-channel, α-subunit

Nav1.1 Nav1.2 Nav1.3 Nav1.4 Nav1.5 Nav1.6 Nav1.7 Nav1.8 Nav1.9 Nav, beta1 Nav, beta2 Nav, beta3 Nav, beta4 Cav2.1 (PQ) Cav2.2 (N) Cav1.2 (L) Cav1.3 (L) Cav2.3 (R) Cav1.4 (T) Cav3.1 (T) Cav3.2 (T) Cav3.3 (T) BKalpha BKbeta1 BKbeta2 BKbeta3 BKbeta4 Kv2.1 Kv2.2 Kv3.1 Kv3.2 Kv6.1 Kv6.2 Kv9.2 Kv9.3 Kv4.1 Kv4.2 Kv4.3 Kv1.4

SCN1B SCN2B SCN3B SCN4B CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4
Voltage gated K+-channel

Voltage gated Ca2+-channel

Large conductance, Ca2+-activated K+-channels, α-subunit Large conductance, Ca2+-activated K+-channels, b-subunits

KCNB1 KCNB2 KCNC1 KCNC2 KCNG1 KCNG2 KCNS2 KCNS3 KCND1 KCND2 KCND3 KCNA4
1

Percentage of total expression within each group


				
Lingjuan Ma Lingjuan Ma
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