CLINICAL TRANSFUSION MEDICINE by ill20582

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									                                                                Transfusion therapy and alternatives:
                                                 current status and prospects of oxygen carriers ("blood substitutes")
                                                  (Coordinators: C. Prowse, A. Mozzarelli, J. Van Hilten, V. Hafner, K. Lowe)
                                                                                  Residential Course
                                                                           Parma (Italy), 11-15 April 2007


Wednesday, 11/4/2007            Evening:     Arrival to the Hotel                                                        (Dinner)
Thursday, 12/4/2007             Morning:     Introduction. Blood donation and Transfusion Medicine in Europe
 9,00- 9,30   Opening of the course (ESTM President and Coordinators). Presentation of participants.
 9,30 -9,40   Introduction (ESTM President and Coordinators)
 9,40-10,10   The changing scene of Transfusion in Europe (V. Hafner)                                                         10,10 Coffee-break
10,40-11,10   Transfusion Medicine in the 21 st Century (V. James)
11,10-11,40   Benefits and risk perceptions of blood and blood substitutes (K. C. Lowe)
11,40-12,10   What are the alternatives to conventional transfusion (C. Prowse)
12,10-12,30   Discussion                                                                                                      12,30 Lunch
Thursday, 12/4/2007             Afternoon:   Anaesthesiological and clinical transfusion alternatives
14,00-14,30    Autologous transfusion (V. James)
14,30-15,00    Re-transfusion of autologous blood in obstetrics (E. Schatz)
15,00-15,30    Necessary precautions before and during operation to minimise use of blood transfusion in surgery (K. Lilaj)
15,30-16,10    Clinical indications of transfusion alternatives (A. Brand)                                                    16,10 Coffee-break
16,40-17,10    Patient cases in desperate need of haemoglobin substitutes (A. Brand)
17,10-18,00    Case-based teaching work and discussion                                                                        19,30 Dinner
Friday, 13/4/2007               Morning:     "Blood substitutes": from research to clinical practice
 8,00- 8,20   Haemoglobin structure and function (A. Mozzarelli)
 8;20- 8;50   Biochemistry of oxygen and CO2 transport (M. Perrella)
 8,50- 9,20   Pathophysiology of oxygen transport (A. Eke)
 9,20- 9,40   Blood substitutes: haemoglobin-based oxygen carriers (S. Bruno)
 9,40-10,00   Current issues of haemoglobin-based oxygen carriers (S. Bettati)                                                10,00 Coffee-break
10,30-11,10   Lessons from clinical studies with haemoglobin-based oxygen carriers (C. Prowse)
11,10-11,40   Perfluorocarbons as blood substitutes: chemistry and properties (K. C. Lowe)
11,40-12,10   Perfluorocarbons: animal and clinical studies (S. Faithfull)
12,10-12,30   Panel discussion on differences between perfluorocarbon-based and haemoglobin-based oxygen carriers             12,30 Lunch
Friday, 13/4/2007               Afternoon:   "Blood substitutes": critical evaluation
(14,00-16,00) (Research and clinical information from industries: 20' interventions)                                    16,00 Coffee-break
16,30-17,00 Experimental studies and clinical application of low concentrated perfluorochemical emulsion Perftoran (E. Maesky)
17,00-17,30 First generation haemoglobin-based oxygen carriers, biochemical and physiological research perspectives:
                biochemistry and manufacturing (A. Alayash)
17,30-18,00 Panel discussion on critical evaluation of "blood substitutes"                                              19,30 Dinner
Saturday, 14/4/2007             Morning:     Expectations for the clinical use of haemoglobin-based oxygen carriers
 8,30- 9,10 First generation haemoglobin-based oxygen carriers, biochemical and physiological research perspectives:
              physiology and toxicity (A. Alayash)
 9,10- 9,50 Which types of patients might benefit from haemoglobin-based oxygen carriers Prowse)
 9,50-10,10 Expectations by cardiac surgeons (C. Beghi)
10,10-10,30 Expectations by anaesthesiologists (K. Lilaj)                                                                     10,30 Coffee-break
10,00-11,30 Opinions on haemoglobin-based oxygen carriers by different stakeholders in transfusion (J. Van Hilten)
11,30-12,30 Case-based teaching work and discussion                                                                           12,30 Lunch
Saturday, 14/4/2007             Afternoon:   Ethical, social, economical and political aspects
                                               of the use of "blood substitutes" in clinical practice
14,00-14,30   Patient safety and quality care: the role of Transfusion Medicine (V. Hafner)
14,30-15,00   Impact of blood substitutes on promotion of voluntary blood donation in Europe (J. Koistinen)
15,00-15,30   Are European clinical and transfusion specialists "ready" to understand and accept oxygen carriers? (U. Rossi)
15,30-16,00   Discussion                                                                                                     16,00 Coffee-break
16,30-17,00   Blood substitutes: role of European Union and Council of Europe (J. Koistinen)
17,00-17,20    Discussion
17,20-17,30   Conclusion of the course                                                                                       20,00 Social Dinner

Sunday, 15/4/2007               Morning:     Departure from the Hotel

___________________________________________________________________________________________________________________________________
ESTM - Viale Beatrice d'Este 5, I-20122 Milano, Italy; Tel.: +39/02/58.31.65.15 - Fax: +39/02/58.30.81.11 - E-mail: estm.secretariat@flashnet.it
Course venue: Meeting room of the University of Parma, a short walking distance from the course Hotel accomodation.
Hotel accommodation at: Starhotels Du Parc, Viale Piacenza 12/C, I-43100 Parma (Italy)
Tel. +39/0521/29.29.29 - Fax +39/0521/29.28.28 - Website: www.starhotels.com - e-mail: meeting.duparc.pr@starhotels.it
_____________________________________________________________________________________________________________________________ _______________________________________________________________________________________________________________________________________




                                                                                                                    Faculty members

Chris Prowse (co-Coordinator), Research Director, Scottish National Blood Transfusion Service, Edinburgh, Scotland, Great Britain; Andrea
Mozzarelli (co-Coordinator), Professor of Biochemistry, Faculty of Pharmacy, Dept. of Biochemistry and Molecular Biology, University of
Parma, Parma, Italy; Joost van Linten (co-Coordinator), Corporate Staff Member, Clinical Research, Sanquin, Leiden, The Netherlands;
Valentina Hafner (co-Coordinator), Quality of Health Systems, Division of Country Support, WHO Regional Office for Europe, Copenhagen,
Denmark; Kenneth C. Lowe (co-Coordinator), Associate Professor and Reader in Biotechnology, School of Biology, Faculty of Medical and
Health Sciences, University of Nottingham, Nottingham, Great Britain; Abdu Alayash, Chief, Laboratory of Biochemistry and Vascular Biology
(LBVB), Division of Haematology, Office of Blood Research and Review, Centre for Biologics Evaluation and Research, Food and Drug
Administration, NIH, Bethesda (Maryland), USA; Cesare Beghi, Professor of Cardiac Surgery, Faculty of Medicine, University of Parma, Parma,
Italy; Stefano Bettati, Professor of Medical Physics, Faculty of Medicine, Dept. of Biochemistry and Molecular Biology, University of Parma,
Parma, Italy; Anneke Brand, Professor of Transfusion Medicine, University of Leiden; Dept. of Research and Development, Sanquin Blood
Bank, Region Southwest; Leiden, The Netherlands; Stefano Bruno, Assistant Professor of Biochemistry, Faculty of Pharmacy, Dept. of
Biochemistry and Molecular Biology, University of Parma, Parma, Italy; Andras Eke, Professor of Physiology, Institute of Human Physiology
and Clinical Experimental Research, Semmelweis University, Budapest, Hungary; Simon Faithfull, Medical, Pharmaceutical and Device
Consulting, San Diego (California), USA; Virge James, Emeritus Consultant in Haematology, National Blood Service, Sheffield, Great Britain;
Jukka Koistinen, Professor; former Deputy Director, Finnish Red Cross, Blood Transfusion Service; Helsinki, Finland; Krenar Lilaj, Specialist
Anaesthesiologist, Clinic of General and Digestive Surgery, University Hospital; Lecturer of Anaesthesiology and Intensive Care, Faculty of
Medicine; Tirana, Albania; Eugene I. Maevsky, Professor of Biophysics, Head of Laboratory of Energetic of Biological Systems, Institute of
Theoretical and Experimental Biophysics, Russian Academy of Sciences (ITEB RAS), Deputy Director of ITEB RAS, Pushchino, Moscow,
Russia; Michele Perrella, Professor of Molecular Biology, Faculty of Medicine, Dept. of Biomedical Sciences and Technologies, University of
Milano, Milano, Italy; Umberto Rossi, ESTM President, Milano, Italy; Erwin Schatz, Department of Anaesthesiology and Intensive Care
Medicine, General Hospital Linz (AKH-Linz), Linz, Austria.
_____________________________________________________________________________________________________________________


                                                                                                        PRACTICAL INFORMATION

Applications should ordinarily be sent as soon as possible. The deadline is 10/3/2007.
Applications may be accepted, in extreme cases, until the 5/4/2007.
Early application is strongly advisable to ensure adequate hotel reservation.
Notification of the registration with full practical information will follow in due course.
The fee of 940 Euro (single room), or of 720 Euro (shared double* room), includes board and lodging from Wednesday 11/4/2007 night
(dinner included) to Sunday 15/4/2007 morning (breakfast included), and covers accommodation at the hotel, the meals during the course,
the Proceedings and other didactic material, the cost (travel, board and lodging) of the participation of teachers, and the ESTM
organisational expenses for the preparation of the course. Travel expenses are at the charge of participants. Participants from Parma, not
needing hotel accommodation (bed and breakfast), will pay a reduced fee of 500 Euro.
Payment of the registration fee should be made:
- through bank transfer to the "ESTM" (account n. 49/36561, Credito Artigiano, C.so Magenta 59, 20123 Milano - Italy; IBAN code:
  IT 62 Y0351201614000000036561; SWIFT Code: ARTI IT M2): all bank expenses must be covered by the participant,
- or by "non transferable" bank cheque in Euro (for participants from the European Union), or international cheque, drawn to
  "ESTM" and sent by mail, together with the application form, to:
  ESTM, Viale Beatrice d'Este 5, I-20122 MILANO, Italy - Tel. +39/02/58.31.65.15 - Fax +39/02/58.30.81.11.
Registrations without payment, or evidence of payment, will not be accepted.
The number of participants foreseen is until 100. In case the number of applications should exceed the number of available places, a
selection of applications may be made on the basis of the chronological order of arrival and the judgement of the course coordinators.
The course is subject to cancellation, owing to causes beyond control, or in the unlikely case that the required minimum number of
registrations should not be reached. In this case, a written notification of the cancellation will be sent to all registrants before the course,
with full refund.
The registration fee includes a book of Proceedings of the course, to be distributed at the beginning of the course, and an attendance
certificate, to be delivered at the end of the course.
Knowledge of English is useful.
The ESTM courses have been approved by the Royal College of Pathologists of London as being appropriate for Continuing Medical
Education (CME) purposes, at the rate of 1 CME credit per hour.
Application has also been made for accreditation by the European Council for Accreditation in Hematology of the European Hematology
Association (ECAH/EHA): based on the experience of the previous ESTM courses, we expect the answer to be given before the beginning
of the course.
Requests of cancellation received until 2 months before the beginning of the course entitle to a full refund. A charge of 25% will be made
for requests of cancellation received between 60 and 30 days before, and of 50% between 29 days and 10 days before the beginning of the
course. Cancellations received less than 10 days before the beginning of the course will not be reimbursed. All requests of cancellation
must be done in written, signed and sent by mail, and can be anticipated by fax and/or e-mail transmission. All reimbursements will be
dealt with after the end of the course.



(* accepted only with the indication of the sharing participant)
    ____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________




____________________________________________________________________________________________________________________________________________________________________________________________________________ ______________________________________________________________




APPLICATION FORM
(to be filled and sent by mail to the ESTM - Viale Beatrice d'Este 5, 20122 Milano, Italy,
              and anticipated by fax - +39/02/58.30.81.11 - and/or e-mail - estm.secretariat@flashnet.it ).


Family name......................................................…….........……............... First name..............….......................…………................... .........……………

Institute.......................................................................................................... .......................................................................……………………………….

Address…………….......................................................................…….. Town................................ ...................… Postal code...................……………

Country............................…………................. Tel.........................................................…………. Mobile tel. …………………………………….…

Fax.....................................................…..…….. E-mail ……………………………………………………………………………………..…………….

I APPLY FOR PARTICIPATION TO THE ESTM RESIDENTIAL COURSE (11-15 April 2007):

    "Transfusion therapy and alternatives: current status and prospects of oxygen carriers ("blood substitutes")"
_______________________________________________________________________________________________________________________________

                                                                                                                940 Euro (single room), or
O I include a copy of a bank transfer to the ESTM of                                                            720 Euro (shared double room) *
         (all bank expenses must be covered by the participant)
                                                                                                                500 Euro (for participants from Parma, not needing hotel accommodation)

         (account n. 49/36561, Credito Artigiano, C.so Magenta 59, I-20123 Milano (Italy); IBAN code IT 62 Y0351201614000000036561; SWIFT code ARTI IT M2)

O         I include a "non transferable" bank cheque in Euro
          (for participants from the European Union),                                                           940 Euro (single room), or
           or international cheque, drawn to "ESTM" of                                                          720 Euro (shared double room) *
                                                                                                                500 Euro (for participants from Parma, not needing hotel accommodation)


(* accepted only with the indication of the sharing participant)
 ______________________________________________________________________________________________________________________________________



    INFORMATION ABOUT ARRIVAL
     Means of transportation  plane (flight number: ……………………)                                                                                                      bus                               train                              car

           Date ………………………. Time ………………………………….…………….
     Will follow later, as soon as possible.




    NOTES OR COMMENTS TO THE ESTM

								
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