Curavisc®: successful study regarding the treatment of chronic facet
Date: 15.12.2009 - 09:59
Category: Health & Medicine
Press release from: curasan AG
A new study was presented at the 4th Annual Congress of the German Spine Society in Munich – it demonstrated the long-term
effect of Curavisc® in the treatment of chronic facet syndrome
Kleinostheim, Germany – It has now been proven that the use of curasan AG’s hyaluronic acid preparation Curavisc® is safe
and sustainably effective also for the treatment of chronic facet syndrome.
Facet syndrome is a chronic pain syndrome caused by an irritation of the joint capsules, mainly in the lumbar spine. It
manifests itself as persistent pain that is often difficult to treat. Reasons for the irritation include chronic strain, osteoarthritis
or intervertebral disc degeneration.
At the 4th Annual Congress of the German Spine Society, held in Munich from 10th until 12th December, Dr. Hermann
Keller presented the open, monocentric study that was carried out at the Spinal and Intervertebral Disc Centre at the
Grünewald Clinic in Aschaffenburg, Germany.
A total of 60 patients aged between 40 and 89 had their most badly affected spinal segment, as well as the facet joints located
directly above and below, denervated using a highly concentrated glucose solution and were then treated three times at weekly
intervals with the hyaluronic acid preparation Curavisc® mini. All the patients were systematically treated in advance with
anti-inflammatory drugs, 35 of them received accompanying physiotherapy and none of them got an NSAID.
The clinical evaluation in each case was carried out after the final injection using a 6-point scoring system. 24 patients (41%)
reported being free of symptoms and 27 (46%) reported a significant improvement.
The individual pain status was assessed on the basis of visual analogue scales (VAS). The symptoms of pain and discomfort
decreased continuously for all criteria as the three-week course of treatment progressed; pain at rest by 77%, pain on initial
movement by 79% and pain during movement by 78%.
Dr. Hermann Keller was impressed by the positive clinical results: “Already during the period of treatment, it was possible to
achieve success for most of the patients. Particularly noteworthy is the fact that improvements for many patients did not just
retain after the treatment had ceased, but continued to increase throughout the follow-up phase.”
The HA product Curavisc® mini for intra-articular treatment is easy to use and was tolerated extremely well. None of the 60
patients had complaints during or after the treatment that could be traced back to the injections.
Conclusion of the study: the injection-based treatment with the hyaluronic acid preparation Curavisc® mini appears to be an
alternative treatment for chronic facet syndrome, well accepted by the patients.
Background information about curasan AG:
Exchange listed curasan AG (ISIN: DE 000 549 453 8) is one of the leading firms in the field of regenerative medicine
especially in bone and tissue regeneration. In addition to the synthetic Cerasorb® bone substitution and regeneration material,
the company has developed a future-oriented product pipeline. The goal during the next few years is to have further medical
products ready for market rollout via well-positioned contractual partners in various market segments.
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