CHAPTER 17 Aromatic Substitution Reactions by mercy2beans119


									CHAPTER 17: Aromatic Substitution Reactions

I. Electrophilic Aromatic Substitution Reactions
    A. The Reactions
       1. Halogenation
       2. Nitration
       3. Sulfonation
       4. Friedel-Crafts Alkylation
          a. Mechanism
          b. SN1 vs. SN2
          c. Issues: Rearrangement
          d. Other Electrophiles
       5. Friedel-Crafts Acylation
    B. Effect of Substituents
       1. Reactivity
          a. Observations
          b. Activators
          c. Deactivators
       2. Directing Effects
          a. Observations
          b. Ortho/Para Directors: An Explanation
          c. Meta Directors: An Explanation
    C. Multiple Substituents
       1. Direct Same Place
       2. Direct to Different Locations
    D.Polycyclic Aromatics
II. Nucleophilic Aromatic Substitution
    A. Diazonium Ion
       1. Formation
       2. Subsequent Reactions
          a. Form Aryl Iodide
         b. Form Aryl Fluoride
         c. Form Phenol
         d. Form Nitrile
    B. Addition-Elimination
III. A Few More Reactions
    A. Reduction of Nitro Group
    B. Reduction of Carbonyl
    C.Oxidation of Benzylic Carbon

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