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					                                        BIOGRAPHICAL SKETCH


                                       James G. Graham, Ph.D.
                             Center for Ethnobiology and Natural Products
                                    Florida International University
                                             Miami, Florida



EDUCATION/TRAINING

            INSTITUTION AND LOCATION                 DEGREE          YEAR(s)      FIELD OF STUDY

University of Pittsburgh, Pittsburgh, PA         B.S.              1992-1994 Chemistry
University of Illinois at Chicago, Chicago, IL   Ph.D.             1994-2001 Pharmacognosy


A. Positions and Professional Memberships

Positions and Employment (in chronological order)

1990-1992    Analytical Toxicologist, Pharmakon, Inc., Pittsburgh, PA
1994-2001    Research Assistant, Program for Collaborative Research in the Pharmaceutical
             Sciences, College of Pharmacy, University of Illinois at Chicago
1997-2001    Production Associate, NAPRALERTSM database, University of Illinois at Chicago
1997-2001    Associate Investigator, National Institute of Traditional Medicine, Ministry of Health,
             Lima, Peru
2001-2002    Technical Officer, Traditional Medicine Team, Department of Essential Drugs and
             Medicines Policy, World Health Organization, Geneva, Switzerland
2001-        Research Associate in Botany, Field Museum of Natural History, Chicago, IL
2002-        Honorary Research Associate, The New York Botanical Garden, Institute of
             Economic Botany
2002-        Visiting Research Associate, Department of Biological Sciences, Florida
             International University
2002-        Research Associate, Center for Ethnobiology and Natural Products, Florida
             International University


Membership in Professional Societies

1994-        American Society of Pharmacognosy
1994-        Society for Economic Botany
1995-        Society for Ethnobiology
B. Selected Peer-Review Publications (in chronological order)


1. Constant HL, Graham JG, Beecher CWW. 1997. Dereplication of Flavonoid Glycosides using High
Performance Liquid Chromatography/ Mass Spectrometric Analysis. Phytochemical Analysis 8: 176-180.
2. Kennelly EJ, Gerhauser C, Song L, Graham JG, Beecher CWW, Pezzuto JM, Kinghorn AD. 1997.
Induction of Quinone Reductase by Withanolides isolated from Physalis philadelphica (Tomatillos).
Journal of Agriculture & Food Chemistry 45: 3771-3777.
3. Determination of Betulinic Acid in mouse blood, tumor and tissue homogenates by Liquid
Chromatography-Electrospray Mass Spectrometry. 1999. Shin YG, Cho KH, Chung SM, Graham JG,
DasGupta TK, Pezzuto JM. 1999. Journal of Chromatography B 732: 331-336.
4. Pharmacokinetics and Tissue Distribution of Betulinic Acid in CD-1 Mice. 1999. Udeani GO, Zhao G.,
Shin YG, Cooke BP, Graham JG, Beecher CWW, Kinghorn AD, and Pezzuto JM. Biopharmaceutics &
Drug Disposition 20: 379-383.
5. Graham JG, Fabricant DS, Quinn ML, Farnsworth NR. 2000. Plants Used Against Cancer: An Extension
of the Work of Jonathan Hartwell. Journal of Ethnopharmacology 73: 347-377.
6. Lee D, Cuendet M, Schunke Vigo J, Graham JG, Cabieses F, Fong HHS, Pezzuto JM, Kinghorn AD.
2001. A Novel Cyclooxygenase-Inhibitory Stilbenolignan from Aiphanes aculeatea. Organic Letters 3:
2169-2171.
7. Seo EK, Kim NC, Mi Q, Chai HB, Wall ME, Wani MC, Navarro DA, Burgess JP, Graham JG, Cabieses
F, Tan GT, Farnsworth NR, Pezzuto JM, Kinghorn AD. 2001.Macharistol, a New Cytotoxic
Cinnamylphenol from the Stems of Machaerium aristulatum. Journal of Natural Products. 64: 1483-1485.
8. Blatt CT, Chávez D, Chai H, Graham JG, Cabieses F, Farnsworth NR, Cordell GA, Pezzuto JM,
Kinghorn AD. 2002. Cytotoxic Flavonoids from the Stem Bark of Lonchocarpus aff. fluvialis.
Phytotherapy Research 16: 320-325.
9. Gu JQ, Park EJ, Schunke Vigo J, Graham JG, Fong HHS, Pezzuto JM, Kinghorn AD. 2002.
Activity-Guided Isolation of Constituents of Renealmia nicolaioides with the Potential to Induce the Phase
II Enzyme Quinone Reductase. Journal of Natural Products 65: 1616-1620.
10. Jang DS, Park EJ, Hawthorne ME, Schunke Vigo J, Graham JG, Cabieses F, Santarsiero B, Mesecar
AD, Fong HHS, Mehta RJ, Pezzuto JM, Kinghorn AD. 2002. Constituents of Musa x paradisiaca Cultivar
with the Potential to Induce the Phase II Enzyme, Quinone Reductase. Journal of Agriculture and Food
Chemistry 50: 6330-6334.
11. Su EJ, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Schunke Vigo J, Graham JG, Cabieses F, van
Breemen RB, Fong HHS, Farnsworth NR, Pezzuto JM, Kinghorn AD. 2003. Activity-Guided Isolation of
Novel Norwithanolides from Deprea subtriflora with Potential Cancer Chemopreventive Activity. Journal
of Organic Chemistry 68: 2350-2361.
12. Activity-Guided Isolation of Chemical Constituents of Muntingia calabura using a Quinone Reductase
Induction Assay. Su BN, Park EJ, Schunke Vigo J, Graham JG, Cabieses F, Fong HHS, Pezzuto JM,
Kinghorn AD. 2003. Phytochemistry, in press.
13. Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth, NR.
2003. Antimycobacterial Evaluation of Peruvian Plants. Phytomedicine, in press.