Supporting Information_ 1H and 13C NMR Spectra by hcj

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									Supporting Information: 1H and 13C NMR Spectra

Synthesis of 2-substituted 9-oxa-guanines {5-aminooxazolo[5,4d]pyrimidin-7(6H)-ones} and 9-oxa-2-thio-xanthines {5mercaptooxazolo[5,4-d]pyrimidin-7(6H)-ones}
Subrata Mandal1, Wen Tai Li1, Yan Bai2, Jon D. Robertus2 and Sean M. Kerwin*,1,2

Address: 1College of Pharmacy, 1 University Station, University of Texas, Austin, TX, 78712, USA and 2Department of Biochemistry,1 University Station, University of Texas, Austin, TX, 78712, USA

Email: Sean M. Kerwin - skerwin@mail.utexas.edu

* Corresponding author

S1

O HN H2N N 2b N O

O HN H2N N 2b N O

S2

O HN H2N N 2c N O N3

O HN H2N N 2c N O N3

S3

O EtO H2N N O 3a

O EtO H2N N O 3a

S4

O EtO H2N N O 3b

O EtO H2N N O 3b

S5

O EtO H2N N O 3c N3

O EtO H2N N O 3c N3

S6

O EtO HN O 5b CN

O EtO HN O 5b CN

S7

O EtO HN O 5c CN N3

O EtO HN O 5c CN N3

S8

O EtO HN HN O Ph 6a S N O

O EtO HN HN O Ph 6a S N O

S9

O EtO HN HN O Ph 6b S N O

O EtO HN HN O Ph 6b S N O

S10

O EtO HN HN O Ph 6c S N O N3

O EtO HN HN O Ph 6c S N O N3

S11

O EtO N HN O Ph A S N O Me N3

S12

O HN HS N 7b N O

O HN HS N 7b N O

S13

O HN S N N Me O 8a

O HN S N N Me O 8a

S14

O HN S N N Me O 8b

O HN S N N Me O 8b

S15

O HN S N 8c N Me O

O HN S N 8c N Me O

S16

O HN OH HO HO MeO O S N 8d N Me O

O HN OH HO HO MeO O S N 8d N Me O

S17

O HN S Ph N N N N N Me O

9

O HN S Ph N N N N N Me O

9

S18

NOE HN H H H N N N 9 S H H

O N Me N NOE O

NOE NOE H H H H N N N 9 HN S H H

O N Me N O

S19

O NOE H H H H N N N 9 HN S H H N N Me O

S20

O HN O N N N N S N N Me O

10

O HN O N N N N S N N Me O

10

S21


								
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