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					International Conference of Genomics 2009·Beijing

Organizers

The Beijing Institute of Genomics, CAS

The Genetics Society of China

Conference time & Venue
Oct. 21 - 23 ,2009 Jiuhua Group
Jiuhua Resort & Convention Center, Xiaotangshan, Changping District, Beijing, China

Conference URL: http://icg.big.ac.cn

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President of the conference
Jun Yu

Organizing Committee
Director: Jun Yu Associate Director: Bin Han Members:
Caixia Guo, Changqing Zeng, Dengke Niu, Guozhen Liu, Hongxing Lei, Huijun Yuan, Jiang Liu, Jun Tan, Jingdong Han, Jurg Ott, Lin Wu, Qianfei Wang, Qinghe Xing, Qinghua Zhang, Qingyou Xia, Song Qin, Quanqi Zhang , Siqi Liu, Wei Huang, Wen Wang , Liping Wei,

Yongliang Zhao, Yuzhong Zhang , Yungui Yang

Secretaries: Xiangdong Fang , Jiangwei Yan Scientific Program Committee Directors: Boqin Qiang , Chung-I Wu, Runsheng Chen, Shengli Yang Members:
Tomas Lindahl, Bin Han, JunYu, Depei Liu, Dongxin Lin, Guoping Zhao, Lin He, Liping Wei, Shujun Cheng, Yongbiao Xue, Zhaoqi Wang

Secretary: Yungui Yang

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Perface
The International Conference of Genomics (ICG-2009) organized by the Beijing Institute of Genomics (www.big.ac.cn), Chinese Academy of Sciences and the Genetics Society of China (www.chinagene.cn), will be held in Beijing, China on October 21-23, 2009. ICG-2009 will focus on "Challenges and Opportunities in the Age of Genomics", aiming to bridge the gap amid academic researchers and investors/manufacturers in the field of genomics and bioinformatics all over the world, and to explore the potential for genomics approaches to medical and therapeutic relevance.

Conference Theme and Topics
Conference Theme
Challenges and Opportunities in the Ages of Genomics

Conference Topics
1) Outstanding Unanswered Questions in the Age of Genomics 2) Genome Stability and Epigenetics 3) Bioinformatics and Computational Biology 4) Genomics and Cellular Evolution

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Invited Speakers
Errol C. Friedberg, Department of Pathology,UT Southwestern Medical Center.

Research Interests:
Friedberg's laboratory is interested in understanding the molecular mechanisms by which cells repair and tolerate DNA damage and thereby mitigate against the phenotypic consequences of mutational alterations.

Title: Tolerance of DNA damage by translesion DNA synthesis
Kevin White, Department of Human Genetics,The University of Chicago.

Research Interests:
Kevin White's research focus on studing the coordinated action of networks of genes that control developmental and evolutionary processes. We have particular focus on building genome-wide models of transcriptional networks, and we use an integrated approach that makes use of gene expression microarrays, large-scale protein-protein and protein-DNA interaction analyses, systematic RNAi analysis and high throughput polymorphism detection.

Title : Defining genomic networks in breast cancer
Tomas Lindahl, Cancer Research UK London Research Institute.

Research Interests:
Instability of DNA under in vivo conditions can be the consequence of exposure to environmental mutagens and cytotoxic compounds, but a major cause is the susceptibility of DNA to endogenous events such as spontaneous hydrolysis, oxidation, and interaction with reactive metabolites. DNA damage caused by endogenous compounds is largely corrected by the base excision-repair process, initiated by DNA glycosylases that excise altered bases. Using purified human enzymes, the base excision-repair process has been reconstituted with DNA and chromatin substrates.

Title:

Genome Instability and DNA Repair Defects in Human Disease

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Quanzhen Li, University of Texas Southwestern Medical Center.

Research Interests:
Li's research interest include Developing and using high through-put microarray and the 2nd-generation sequencing and other genomic analysis tools to identify and characterize disease-related genes and pathways.

Title: Identification of Pathogenic Pathways and Biomarkers for
Systemic Lupus Erythematosus Using High-throughput Genomics and Proteomics Technologies

Qiang Tian, Institute for Systems Biology.

Research Interests:
Dr. Tian leads the Stem Cell Group, which is pioneering integrated genomic and proteomic approaches for the interrogation of mammalian stem cells, primarily hematopoietic, embryonic, and cancer stem cells. The focus of his research is to identify better stem cell markers and to elucidate mechanisms governing stem cell self-renewal vs. differentiation through global mRNA and protein profiling and through the illustration of protein-protein interaction networks of key signal transduction pathways essential for both stem cell development and tumorigenesis, such as the Wnt/catenin pathway.

Title: In Search of Cancer Stem Cell: Integrating
Transcriptomic, Proteomic,and Single Cell Analysis

Zhaoqi Wang,Leibniz Institute for Age Research.

Research Interests:
DNA damage response includes damage signalling, DNA repair, cell cycle control and operation of apoptosis. Studying the mechanisms of DNA damage response will advance our understanding of fundamental cellular processes, tissue homeostasis and age-related pathologies (such as cancer and neurodegeneration).

Title:

DNA damage response molecule MCPH1 maintains mammalian brain size by regulating the neuroprogenitor division mode

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Manyuan Long, Department of Ecology and Evolution ,The University of Chicago.

Research Interests:
An interesting problem in evolutionary biology is how genes with novel functions originate. The research in Long's laboratory focuses on this problem, although they are also interested in other issues of molecular evolution. Interest in evolutionary novelties can be traced back to the time of Darwin. However, studies of the origin and evolution of genes with new functions have only recently become possible and attracted increasing attention.

Title:

The male genes out of X and the role of male germline X inactivation

Yi Zhang, Howard Hughes Medical Institute,University of North Carolina at Chapel Hill.

Research Interests:
Dr. Yi Zhang is currently an investigator at the Howard Hughes Medical Institute and a professor in the Department of Biochemistry and Biophysics at The University of North Carolina at Chapel Hill. He obtained his Ph.D. from The Institute of Molecular Biophysics at His current interest centers on the question of how dynamic changes in chromatin structure affect gene expression, cellular proliferation and cancer.

Title: Could the DNA demethylase please stand-up?

Yong Duan,UC Davis Genome Center and Department of Applied Science.

Research Interests:
Prof. Duan's research interest focus on the following questions: Protein Folding and Aggregation, Simulation Method Development, Structure and Dynamics of G-Protein Coupled Receptors, DNA-protein interaction, Computer Aided Drug Design, Computing Resources etc.

Title: To be determined

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Shyam Prabhakar, Genome Institute of Singapo.

Research Interests:
Shyam Prabhakar's research interest focus on the following feilds: Transcriptional Regulation, Computational Genomics, and Evolutionary Genomics.

Title: To be determined
ChuckCannon,XishuangbannaTropical Botanic Garden,CAS; Texas Tech University.

Research Interests:
Through a combination of basic research, applied conservation, local outreach and student training, they hope to have a positive impact on the future condition and management of natural forests and the communities they sustain. They integrate experience across a wide range of scientific approaches and techniques from systematics and phylogenetics to remote sensing and genomic biology.

Title:Assembly-free comparative genomics: finding the needle in
the haystack

HuiWang,NERC/CentreforEcology&Hydrology(CEH)Oxford

Research interests
Currently working on plant viruses, including plant anti-virus gene silencing, plant virus ecology, plant-virus co-evolution, and plant virus impact on human health (hay fever). Previous research experience on molecular parasitology, molecular virology of animal and human viruses.

Title:

Integrated Nucleotide Bias of DCL, AGO, and RDR in

Plant Anti-virus Gene Silencing

Jun Yu,Beijing Institute of Genomics, CAS.

Research Interests:
Dr. Yu’s primary research interests include genome biology and bioinformatics. He has led many major genome projects in China, including the Human Genome Project (the Chinese effort), the Superhybrid Rice Genome Project, the Silkworm Genome Project, and the Chicken Genome Diversity Project, which all resulted in
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high-impact publications in major international journals, including Science, Nature, and PLoS Biology. He has published over 100 scientific papers and a few dozens of books and book chapters.

Title:Gene-centric

purine content variability (PCV) and

strand-biased gene distribution (SGD) among eubacterial genomes。

Chung-I WU,Beijing Institute of Genomics, CAS.

Research Interests:
Prof. Wu’s research activities are mainly involved in the following four areas: 1) Molecular and population genetics of speciation in Drosophila. 2) Evolutionary genomics in Drosophila, especially microRNAs. 3) Evolutionary genomics in human and higher primates. 4) Theories of natural selection for application to human and Drosophila.

Title: Selection and introgression driving the domestication of
cultivated rice

Bin Han,Beijing Institute of Genomics, CAS.

Research Interests:
Professor Han is focusing on rice genome sequencing and re-sequ comparative genome analysis of rice subspecies, and rice fu genomics. Over the past several years, he and his laboratory have succ finished sequencing and analysis of Oryza sativa japonica chromos construction of japonica fine physical maps, and rice chromosome 4 DNA chips and its expression profiling which were published on Genome Research and Plant Cell, respectively.

Title: To be determined
Runsheng Chen,Institute of Biophysics, CAS.

Research Interests:
Professor Runsheng Chen is one of the pioneer scholars develop researches on theoretical biology and bioinformatics in China. For mo twenty years, Prof. Chen has led his group to perform a series of s researches in the field of bioinformatics, including the whole

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assembly and annotation for T. tengcongensis B4 (the first bacterium completely sequenced in China), the 1% Human Genome Project, Draft Sequence of the Rice Genome.

Title: To be determined

Yaping Zhang,Kunming Institute of Zoology, CAS.

Research Interests:
adaptive evolution; molecular phylogeny of animals; population genetics and conservation genetics of animal species in China; genetic diversity and origin of domestic animals; genetic diversity and evolution history of human populations in East Asia, ;genome evolution.

Title: To be determined

Haiying Hang,Institute of Biophysics, CAS.

Research Interests:
Hus1, Rad1and Rad9 are a group of cell cycle checkpoint genes co from yeast to human. Mutations in the genes lead to malfunction cycle control and repair of damaged DNA. Our recent work conditional knockout mouse technology indicates that Rad9 has inhibitory function. We are currently dissecting the mechanisms h genes work in cell cycle control, DNA repair and tumor prevention

Title:The structure and function of 9-1-1 protein complex

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Liping Wei,School of Life Sciences, Peking University.

Research Interests:
Pathway and regulatory networks underlying neurobiological diseases; Natural antisense and noncoding RNAs: expression, evolution, and regulatory functions ;New bioinformatics methods to study expression regulation and pathway networks.

Title:Trans-NaturalAntisenseTranscriptsIncludingNon-Coding
RNAs in Ten Species: Implications for Expression Regulation

Xiaofeng Cao,Institute of Genetics and Development Biology, CAS.

Research Interests:
Epigenetics, defined as the study of heritable and probably reversible alteration in gene expression without changes in DNA sequence, has greatly expanded our understanding of gene expression and regulation. DNA methylation, histone modifications and RNA directed gene silencing are three major mechanisms in epigenetic regulation. Using both Arabidopsis and rice as model organisms, our lab is interested in understanding how gene expression and plant development are regulated by histone modifications and small non-coding RNAs.

Title: Dicer-like proteins in rice development and small RNA
biogenesis.

Xiujie Wang,Institute of Genetics and Development Biology, CAS.

Research Interests:
The current focus the lab is to develop novel computational methods to analyze the fast increasing genomics, transcriptomics, proteomics and other large-scale biological data, to identify new non-coding regulatory RNA genes in eucaryotic genomes, to decipher their transcription regulatory mechanisms and to construct non-coding RNA involved gene regulatory networks.

Title: Systematic Studies on Plant Small Non-Coding RNAs

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Jingde Zhu,Shanghai Cancer Institute.

Research Interests:
Cancer Epigenetics Gene Therapy

Title: Epigeneic (-omic) perspectives of today’s life science and
personalized medicine: DNA methylation as paradigm

Long Yu, State Key Laboratory of Genetic Engineering, Fudan University.

Research Interests:
Protein domain identification and study of gene function and its application; with Bioinformatics, Gene identification and function and Drug target screening.

Title:To be determined

Dahai Zhu,Institute of Basic Medical Sciences, CAMS and PUMC.

Research Interests:
Myostatin function and signaling transduction during myogenesis; Muscle function as a endocrine organ during disease (type II diabetes) development;Using Chicken as model for study of myogenesis during development.

Title:Systematic identification of coding and non-coding genes
involved in divergent skeletal muscle growth rates of broiler and layer chickens

Taijiao Jiang,Institute of Genetics and Development Biology, CAS.

Research Interests:
Dr. Jiang's lab focuses on developing computational structure and systems approaches to understand complex molecular machineries and interaction networks: their molecular mechanism, dynamics and regulation.

Title: Mapping the coiled-coil interactome of budding yeast
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Guoliang Xu,Institute of Biochemistry & Cell Biology, Shanghai Institutes for Biological Sciences, CAS

Research Interests:
DNA methylation and developmental regulation.

Title:The chromatin determinant of genomic methylation

Bairong

Shen,Center for Systems Biology, Soochow University.

Research Interests:
To understand the disease-related of protein mutation and the relationship between protein function in using of biological information model;Microarray data analysis and modeling; small RNA bioinformatics research;Systems biology simulation of the important disease-related biological networks.

Title:Genome-wide

comparative

analysis

of

the

binding

preference of human unidirectional and bidirectional promoters

Pingkun Zhou ,Department of Radiation Toxicology and Oncology Beijing. Institute of Radiation Medicine

Research Interests: Cell DNA radiation damage repair and cell cycle regulation, radiobiology

Title: DNA-PKcs is necessary for spindle stability and mitotic
progression in response to DNA damage.

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Xingzhi Xu,Laboratory of Cancer Biology, College of Life Science, Capital Normal University.

Research Interests: mechanisms of Chk2 in response to DNA damage DNA damage checkpoint signaling The protein phosphatase PP6 in the DNA damage response

Title: Dephosphorylation of g-H2AX by Protein Phosphatases

Weimin Tong ,Institute of Basic Medical Sciences,CAMS and Peking Union Medical College.

Research Interests: The overall theme of my research is to better understand the basic mechanisms of defects in DNA strand break-sensing molecules, such as poly(ADP-ribose) polymerase (PARP-1) and Nijmegen breakage syndrome (NBS1) in development and tumorigenesis with an emphasis on identifying molecules that specifically collaborate with one another to bring about neoplastic transformation and tumor progression.

Title: The role of DNA strand break-sensing molecule PARP-1
in neuronal tumourigenesis

Xue Zhang ,Institute of Basic Medical Sciences,CAMS and Peking Union Medical College.

Research Interests: Molecular genetics of tumor and single gene disorder

Title: To be determined

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Yong Zhang ,School of Life Science and Technology,Tongji University.

Research Interests: the design of statistical and computational algorithms on high-throughput data to study gene regulation related issues, including the regulatory effects of transcription factor binding, nucleosome positioning, histone modifications, chromatin higher structure and noncoding RNAs, etc.

Title:Computational Analysis of High-throughput Sequencing
Applications on Epigenomic Studies

XiangLv,Institute of basic medical Sciences,Chinese Academy of Medical Sciences & Peking Union Medical College.

Research Interests:
Regulatory network of clustered genes SSO mediated targeted gene therapy

Title:

wiring to control.

Duanqing Pei , Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences.

Research Interests:
Proteinases and their inhibitors in cancer and arthritis Protein trafficking in normal and cancer cells EGFR signaling pathways in lung cancer Transcription factors and stem cell pluripoten

Title: To be determined

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Registration
Registration Fees
Classification Student/Post-doctor Domestic Participants Members of GSC Normal International Participants Student/Post-doctor Normal RMB 700 RMB 800 USD 100 USD 200 RMB 1100 RMB 1200 USD 150 USD 300 Before 08-31-2009 RMB 400 After 09-01-2009 RMB 600

Notes: 1) Earlybird Registration Deadline: August 31, 2009 2) Registration fee includes fee for program materials, all sessions, lunches (Oct.21-23) and dinners (Oct.20-23) but not for accommodation and traffic. 3) GSC: Genetics Society of China 4) Members of GSC and students need to take certificate when checking in.

Payment methods:
1. Bank transfer 2. By cheque 3. Cash on site The account for you to transfer the payment:
Bene Banker's A/C Number Benefictary Banker's Name

001043718 Industrial and Commercial Bank of China,Beijing Municipal Branch,Madian Banking Office,Beijing,PRC No.1 Huayanbeili,Chaoyang District,Beijing,PRC.

Bank Address Banktelephonenumber
SWIFT Code Account beneficiary

86-10-62054175
ICBKCNBJBJM 0200025609014479281 Beijing Institute of Genomics

Address

No.7 Beitucheng West Road,Chaoyang District,Beijing,China Post Code:100029

Important Date
Abstract submission Decision notification Closed Aug 31, 2009 through Sep 20,2009

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Sponsorship Fee and Benefits
Standard and benefits of special sponsorship: A. >100K RMB: 1. 25 min talk on sequencing technology and genomics 2. Propagandize the company rolly on the full screen in opening ceremony 3. Free 2 rooms for 3 days (5 star standard) 4. Items in D; 4 free quota of people to attend the conference including fee of meeting materials, meals, and attendence (total 10K RMB)

B. 80K-100K

RMB(including 80K):

1. 20 min talk on sequencing techology and genomics 2. Propagandize the company rolly on the full screen in openning ceremony 3. Free 2 rooms for 3 days (4 star standard) 4. Items in D; 4 free auota of people to attend the conference including fee of meeting materials, meals,and attendence (total 10K RMB)

C. 50K-70K RMB(including 50K) 1. 15 min talk on sequencing technology and genomics 2. Propagandize the company rolly on the full screen in openning ceremony 3. Free 1 room for 3 days (5 star standard) 4. Items in D

D. 20K-40K RMB (including 20K) 1. Show web of company and link its logo on the home page of the conference web. 2. 1 standard booth of 4 centiare (2*2) with one table, two chairs, and power source. 3. Two peple to attend the conference including fees of meeting materials, meals, and attendance.

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4. Company's propaganda materials in the proceeding. 5. One page (with color) of commercial on interior page of the proceeding. 6. Show company name on the badge.

E. Standard of the commercials for small companies 1. Conference proceedings:cover and back cover (8K RMB; can not advertise but sign in cover and back cover), inside front cover and inside back cover (6K RMB), interior page (4K RMB) Note: The proceeding is 16 Kai-paper; 2. Conference propaganda publication: inside front cover (5K RMB), inside back cover (5K RMB), interior page with color (3K RMB) 3. One standard booth of 4 centiare (2*2) with one table, two chairs, and power source; 10K RMB for each booth . 4. Send out materials: 1.5 K RMB 5. Please interview with the reparatory group on exhibition in a variety of ways Remark: 1. Please supply the introduction of the exhibitor including website, email, fax, and phone. 2. Prepare the propaganda materials ahead and hand in slide before the talk. 3. Bargain on all activities with conference reparatory group to arrange in the agenda; All exhibitors can not act and disturb the conference withoutpermission.

Contact Us
General Inquiries: Jiangwei Yan Telephone:86-10-82995375/5382 Fax:86-10-82995373/5382 Address:No.7 Beitucheng West Road,Chaoyang District,Beijing ,China Post Code:100029 Mail: yanjw@big.ac.cn liyan@big.ac.cn Yan Li

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Description: organizers conference time & venue