Revised 3rd June
CHEM 334 Organic Chemistry
Dr. George Handy
University of South Carolina
Summer II 2009
Ryan Brunner Brunner@mailbox.sc.edu Section 1 Mon-Thurs 9:30-10:15 AM, PSC 205
Zack Coffman email@example.com Section 2 Mon-Thurs 9:30-10:15 AM, PSC 006
Gabriel Ross firstname.lastname@example.org Section 3 Mon-Thurs 9:30-10:15 AM, PSC 201
Jeffery Steen email@example.com
Oscar Cabrices firstname.lastname@example.org Special Recitations and Help Sessions/Grading
Petech Kaewsuya email@example.com all class assignments and exams
Office Hours: Monday – Thursday 12:45-1:15 PM, HESC 114
Class Meetings: Monday – Thursday, 10:30 AM– 12:45 PM, HESC 114
Recitations: Meet according to section
Course Objectives Acquire a solid foundation for the application of concepts from the organic chemistry
lecture, which would include mechanistic organic chemistry and synthetic organic
chemistry applications in the field of pharmaceutical and medicinal chemistry.
Apply Organic Chemistry applications in certain physiological processes.
Exposure to Biochemical processes and concepts.
Survey of prostaglandins and their functions in physiological processes.
Survey of steroids and their functions in physiological processes.
Obtain a firm comprehension of the physical processes of organic chemistry reactions.
Improve writing skills.
Perform oral presentations in front of the class. This will allow students to improve their
public speaking skills and gain confidence speaking in front of others.
Strengthen critical thinking and problem solving skills.
Ability to complete retro-synthetic analysis utilizing the knowledge learned in Chem 333
lecture and Chem 334 lecture.
Improve test-taking skills.
Grading: Exam #1 Tuesday 7/14 100 pts 10:30 -11:30 AM Grading Scale:
Exam #2 Tuesday 7/21 100 pts 10:30 -11:30 AM A = 92% and above
Exam #3 Tuesday 7/28 100 pts 10:30 -11:30 AM B+ = 86% - 91%
Exam #4 Monday 8/3 100 pts 10:30 -11:30 AM B = 78% - 85%
Final Exam: Thurs. 8/6 C+ = 70% - 77%
Comprehensive 200 pts C = 60% - 69%
Supplemental 100 pts D = 50% - 59%
F = below 50%
Recitation Quizzes 100 pts
Total Pts. 700/600 pts
Exams: 1. Exams will be given during scheduled class periods and returned during the following
recitation period. The exam problems will be similar to the assigned textbook problems.
Familiarity with the homework problems will make exams much easier. Organic Chemistry
is an exact science. As a rule, no partial credit is given on tests. Exam dates may be
changed based on the material covered. However, the date of the final exam will not
2. Exams will be returned during recitation and all requests for re-grading must be made
before the end of recitation. It is your responsibility to pick up your test and go through
the answers with your TA. You are required to leave your test with a mark or a note
indicating your concern. Note: An exam presented for re-grading will be completely re-
graded. In 99% of the cases it will lead to a loss of points. All exams need to be
returned to your TA after you have reviewed them before leaving recitation.
3. Due to the coverage and intensity of Chem 334, it will not be possible to give make-up
exams. A student who misses an exam with a medical excuse or death in the family may,
at the instructor's discretion, be able to count 100 pts from the final exam in lieu of the
missed exam. If the student is planning to miss an exam, he or she must contact the
instructor and TA before the day of the exam. The student DOES NOT have the option to
take an exam and give an excuse once the exam is distributed.
4. The final course grades will NOT be posted. The Teaching Assistant and I will be available
to answer any questions regarding final course grades on Thursday, 8/6 between 1:00 p.m.
and 4:00 p.m. only.
5. Final course grades are assigned by the computer. Grade assignments are based strictly
on numbers given in the grading scale. The status of borderline candidates is discussed
carefully. Factors such as attendance, class participation, class quiz average and
preparation for the class is considered before a grade is assigned. Final course grades
will be turned in to the Chemistry Office by 5 PM on Thursday 8/6.
6. Special term papers etc. will not be accepted in lieu of exam grades. Ex:* Term papers will
not satisfy the course requirements in order to raise an assigned grade to a higher grade,
nor will they be accepted to change a failing grade to a passing grade.
7. The final exam will consist of two parts: a comprehensive and a non-comprehensive.
Students who are comfortable with their grade may do a take home assignment to be turned
in during the final exam. Students who wish to improve their grade may take either a
supplemental final (100pts), which is to be taken on the unit that the student received
his/her lowest score, or a comprehensive final (200pts). Students taking the comprehensive
final will be assigned the grade made on the final.
*Please plan your schedule ahead of time to comply with this requirement. You are required to
initial your grade report form after checking your final exam with your TA. A grade will not
be submitted unless this is done.
Concerning the 1. Organic chemistry 334 is extremely demanding and intensive. Students are advised to
Grade Assignment: spend at least 3-4 hours per lecture outside of class time studying the material. This
does not include time spent on homework problems, etc. Your pleasure/work schedule must
be adjusted accordingly, giving you adequate study time. Your success in the course is
DIRECTLY PROPORTIONAL to the time and effort that you invest in studying!
2. Your success in Chemistry 334 is also dependent upon your background in Chem 333. A D
or a C in Chem 333 indicates a weak understanding of the fundamental and basic
principles of Organic Chemistry, which is critical and necessary in understanding the
more detailed and complex topics discussed in Chem 334. Students having a semester or
two between Chem 333 and Chem 334 may forget basic principles and there is a greater
responsibility on the part of the student to review Chem 333 topics thoroughly while
continuing on with Chem 334, or to work with a tutor.
3. A student who has a D or C in Chem 333 or makes below 60% on the first exam is
urged to contact a tutor without delay (there are several tutors who can be recommended,
all of whom work regularly on relevant topics in Chem 333, as well as the current 334
4. Incompletes cannot be assigned due to poor performance in the classroom. A valid
medical reason from the Doctor should be supplied, as well as a letter to the instructor
from the student requesting a grade of incomplete for the semester.
5. A student going into the final exam has three options:
(a) The student is satisfied with their average grade for the four exams and will accept this
grade, exempting the final.
(b) The student will take a supplemental final exam. This exam is taken on the unit for
which the student recorded his/her lowest exam grade. The supplemental exam will be
averaged with the student's four regular exam grades. The supplemental exam can
either help the student or hurt the student, depending on how they perform on the
(c) The student will take the comprehensive final exam. This exam will be comprised of
all the material taught during the course. The comprehensive exam will be compared to
the student's average on the four regular exams. The higher grade will be taken as
the student's final course grade.
Attendance: Attendance is required in class. More than two (2) absences from class will lower your final grade
one half grade (e.g. A to B+). More than three (3) absences will lower your final grade one full
grade (e.g. C to D). Absences in excess of 25% of the class periods (4) will result in an F for the
course. Note that the above rule applies to both excused and unexcused absences, so do not request
that the instructor excuse absences. "Absences from more than 10% of the scheduled class sessions,
whether excused or unexcused, is excessive and the instructor may choose to exact a grade penalty
for such absences." (USC Student Handbook and Policy Guide) Seats will be assigned to facilitate
record keeping. Attendance will be taken in class by the GIA, and those absent will have their names
recorded and posted outside PSC 218. It is the student's responsibility to notify the GIA of errors.
Students arriving later than 10 minutes after the start of class will be counted absent for that
Recitation: Attendance is required at recitations. These recitations are for your benefit, and you should come
prepared to work the assigned homework problems and answer questions. The recitation time will
not be used to go over all the previous week's lecture material. Instead, specific topics may be
reviewed to enhance the students understanding of the concepts. Please review and study the lecture
material very thoroughly before attending recitation. Each student will be required to participate
in the problem solving and discussion. Recitations will be held according to the following format:
1) Please be on time.
2) 4-6 Problems from the homework assignment or class discussion will be selected and assigned for
each week's recitation. This assignment must be done!
3) There will be a short quiz during recitation based on the previous day’s lecture material. After the
quiz has been completed, problem solving will begin. Questions from the quiz and/or homework
will be discussed by the students in recitation, so be prepared.
4) Information discussed in recitation should be neatly copied and included as part of your lecture
notes in your filing system. Be Organized!
Office Hours: Due to the fact that this year some renovations are being done in PSC, it will not be possible to
hold office hours in my office. However I will be available to answer questions after class in the
classroom itself from 12:45- 1:15.
Cheating: Anyone caught cheating in any manner, including plagiarizing, will be prosecuted to the fullest
extent of USC regulations.
Class Notes / Supplementary notes (optional) for CHEM 334 will be available at Copy Pickup at 1830
Course Package: Rosewood Drive.
Important Dates for 1. Comprehensive final exam will be given on Thursday, August 6th from 10:30 a.m. to
CHEM 334: 12:45 p.m. The time and date for the final exam will not be changed under any
circumstances and the final exam will not be given before or after this date. Make
2. Checking Final Exams/Grades Thursday, August 6th between 1 PM-4PM only.
3. July 7th is the last day to withdraw from the class without receiving a W.
4. The instructor is not authorized to assign a W after the date of July 16th. The result of
Exam 1 scheduled on Tuesday 7/14 should indicate whether you should consider
dropping the course. (For instance, a score of 60% or less on Exam 1 would indicate
this.) Any student who feels that he or she is deserving of a W, rather than WF, after July
21st should discuss that with the Dean, Dr. Knapp.
5. Monday, July 20th is the last day to withdraw from class without receiving a WF.
Important Additional Comments
Note I A good performance in Chem 334 depends on:
a) a solid understanding of Chem 333 (Grade of B or better)
b) the time put into the course, systematic daily work, completing homework assignments, preparation for
class, and your ability to learn and retain abstract concepts.
c) Organization of your notes and other information given in class.
Note II Any student whose background in Chem 333 is weak, C or a D, and wishes to continue in Chem 334 is
urged to contact a TA (tutor) on a regular basis for extra help. Suggested Tutors: TBA
Note III A student who has below a letter grade B in Chem 333 and makes below 50% on Test I, is very strongly
urged to consider dropping the course, Audit Chem 333 and retake Chem 334 during another semester.
Note IV Dean Knapp informs us that there are two problems getting out of hand and he requests our help
with them. Quoting a memorandum from Dean Cowley,
"1) If a student withdraws from one of your courses via VIP or the Internet, tell him/her that a hard copy
of the revised schedule should be printed out. That way they have proof that they have in fact withdrawn
from a course within the appropriate time frame. Too many people are claiming they withdrew, but they
have no proof that the system was flawed.
2) Please check your official class rolls as soon as they arrive. If there are students in your class, but not
on the roll they need to take steps to enroll immediately. It will be necessary for them to get an AS199
form (from my office) to request for late registration. These requests to add a course or to change a section
because of class conflicts should not drag on forever."
Summer II Schedule
Unit Chapter/Topic Date
Synthesis, Structure, Properties, Reactions, Spectral 7/7
Properties... of aldehydes and ketones. Includes the Aldol 7/8
Condensation, Robinson Annulation, and the Michael 7/9
Addition Reactions 7/13
Exam 1 10:30 a.m. - 11:30 a.m.
Carboxy Acids: Structure, Synthesis, Properties, and Reactions
Acid Derivatives: Acid Chlorides, Anhydrides, Amides, Esters, 7/15
Claissen Condensation - Malonic Ester, Aceto Acetic Ester 7/20
Ring formation methods: The Diels-Alder Reaction
Exam 2 10:30 a.m. - 11:30 p.m.
Aromatic Chemistry, Benzene Structure, Properties, Reaction
EAS, Phenols, Aromatic Amines, etc…
Special Topic - Benzene Diazonium Chloride Aromatic
Exam 3 10:30 a.m. - 11:30 p.m.
Amines, Lipids: Prostaglandins and Steroids 7/30
Exam 4 10:30 a.m. - 11:30 p.m.
Review Session 8/4
(Comprehensive: 200 pts)
Final (Supplemental: 100 pts): 100 pts from student’s lowest unit Thursday, August 6th
Exam 10:30 a.m. - 12:30 p.m.
Help sessions will be held prior to each test at a time and location that will be announced.
1. Notes for Chem 334 and review problems (Optional) [Available at Copy Pickup on
2. Selected problems from text for Units 1-5 supplied by your teaching assistant.
3. Answers to Problems.
4. Organic Chemistry William H. Brown Ed. 3 with solution manual.
HOW TO TAKE EFFECTIVE LECTURE NOTES FOR THIS COURSE
1. Keep a ring binder for each unit. Example: Unit 1 binder, containing
chapter 15 notes and selected parts of chapter 18.
2. Date each lecture. Do not write on the notes provided. Use a notepad
to take down information not given in the notes. At the end of the day,
go through the notes and organize the material so that you can review
effectively. Remember, the more organized you are, the more you will
be able to gain from your notes.
3. Review the notes that you now have organized as soon as possible after
your lecture and before the next class period. You can benefit more from
the next lecture if you have an understanding of the material from
previous lectures. Use the weekends to review the week's notes. Try to
recall the information by writing the information that you have studied
on a notepad.
4. Attempt homework only after you have organized and reviewed the
notes over and over again.
5. Keep an index at the beginning of each unit.
6. Maintain a copy of your homework in your filing system (ring binder).
7. Maintain your own exams relevant to that unit in the same binder.
8. An easy way to learn structures, mechanisms, etc., is to practice writing
them over and over again. Remember that chemistry and physics are
EXACT SCIENCES, and even a slight error is considered a major
mistake and will result in a loss of points. Critical thinking under
pressure is what exams should teach you.
9. Each of the four 1-hour exams will test you on one unit (four units ==
four ring binders!).
THE ROLE OF THE INSTRUCTOR
1. The instructor is responsible for conveying the lecture material in an organized
manner during class. Students are expected to be attentive and quiet during the
2. Testing the students’ knowledge and understanding of the subject matter, and most
importantly, testing the students’ ability for problem solving and independent
3. Answering questions pertaining to homework problems during set office hours.
4. Assigning grades generated by the computer, based STRICTLY ON NUMBERS
obtained from the four exams; quiz average, and final exam score if applicable. The
instructor will not enter into any discussion pertaining to the grades after the
assignment of the grades, except to answer questions regarding performance on
the final exam.
THE ROLE OF THE TEACHING ASSISTANT
1. Instruct the students during recitation on PROBLEM SOLVING.
2. Answer questions from students during recitation and during office hours only.
3. The TA will not be responsible for assigning grades. However, the TA will be
consulted in order to determine the status of students who are borderline, in which
case class attendance, participation and preparation for recitation may be considered
along with his/her class quiz average, which will be the major factor in determining
the status of borderline students. Input from the TA will be considered.
4. Grade tests fairly and objectively. A grader may assign partial credit at his/her
discretion under special circumstances. As a general rule, no partial credit will be
THE ROLE OF THE STUDENT
1. Review the lecture notes from the previous class. Come prepared for each class
period. Be on time; attendance will be taken during the first 5 minutes of class.
2. Remain quiet and attentive during class. Talking, eating, and drinking will not be
permitted. Students seen talking will be warned once, and then asked to leave the
classroom. This rule will be enforced.
3. Prepare for exams thoroughly using Homework Assignments/Model Questions as
study guides. Attend review sessions.
4. Students must take responsibility for their grade. * Your grade depends on your
background in Chem 333, your ability and the time and effort you put into
preparation for exams.
5. Exams are graded consistently. A test submitted for correction will be regraded. In
99% of cases, this results in the grade being lowered.
6. Be considerate and respectful to your instructor, your TA, and your fellow students.
7. The assignment of the Final Course Grade is final. No changes will be made on
compassionate grounds, ex. losing a scholarship, thereafter. Students are responsible
for passing the course with the grade necessary for their future career. Students must
accept their final grade (with grace and dignity), which is based upon their
8. Enjoy the course, aim high, and do well.