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									LANCET VOL. 363, NO. 9402, JANUARY 3; 2004
Editorial Towards evidence to secure reproductive rights Commentary The Lancet's policy on conflicts of interest--2004 Astrid James, Richard Horton, David Collingridge, John McConnell, James Butcher Drug combinations for malaria: time to ACT? *Patrick E Duffy, Theonest K Mutabingwa Assessing inequalities in maternal mortality Davidson R Gwatkin Enterobacter sakazakii--new foods for thought? Jeffrey M Farber Clinical value of the X chromosome in testicular germ-cell tumours *Leendert H J Looijenga, J Wolter Oosterhuis Vascular higher-level gait disorders--a step in the right direction? Mary P Martin, *Desmond O'Neill Articles Artesunate combinations for treatment of malaria: meta-analysis International Artemisinin Study Group* Dihydroartemisinin-piperaquine against multidrug-resistant Plasmodium falciparum malaria in Vietnam: randomised clinical trial Tran Tinh Hien, Christiane Dolecek, Pham Phuong Mai, Nguyen Thi Dung, Nguyen Thanh Truong, Le Hong Thai, Dong Thi Hoai An, Tran Tan Thanh, Kasia Stepniewska, Nicholas J White, Jeremy Farrar The familial technique for linking maternal death with poverty Wendy J Graham, Ann E Fitzmaurice, Jacqueline S Bell, John A Cairns Mechanisms of disease Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy T Eid, M J Thomas, D D Spencer, E Rundén-Pran, J C K Lai, G V Malthankar, J H Kim, N C Danbolt, O P Ottersen, N C de Lanerolle Case report Subcutaneous echinococcosis of the knee Jesús Guiral, Alberto Rodrigo, Eduardo Tello Research letters Occurrence of Enterobacter sakazakii in food production environments and households M Chantal Kandhai, Martine W Reij, Leon G M Gorris, Olivier Guillaume-Gentil, Mike van Schothorst XIST unmethylated DNA fragments in male-derived plasma as a tumour marker for testicular cancer Takahiro Kawakami, Keisei Okamoto, Osamu Ogawa, Yusaku Okada 1 2 3 5 5 6 8 9 18

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News Patient's death from vCJD may be linked to blood Stephen Pincock Publishers face backlash over rising subscription costs Faith McLellan Tobacco company defends safety of curing process Samuel Siringi Chilean TV channels in court over AIDS ads Claudia Orellana Increased funding for health could help prevent conflict Kathleen Nelson Argentine murder leads to crackdown on doctors Graciela Iglesias Rogers Staffing levels, not industry, dictate FDA review times Hannah Brown Shortage of meningitis vaccine in USA looks likely for 2004 Roxanne Nelson NEWS IN BRIEF China promises to dash hopes of tobacco industry giants Jonathan Watts reporting from Beijing Seminar Transmissible spongiform encephalopathies Steven J Collins, Victoria A Lawson, Colin L Masters Rapid review CCN proteins: multifunctional signalling regulators Bernard Perbal Reproductive health and rights Reproductive health and human rights Adrienne Germain The right to count Wendy Graham, Julia Hussein Reproductive health without rights in Peru J Jaime Miranda, Alicia Ely Yamin Sexual and reproductive health funding: donors and restrictions Pramilla Senanayake, Susanne Hamm Obstetric fistula: the international response France Donnay, Laura Weil Invoking human rights to reduce maternal deaths Rebecca J Cook, Maria Beatriz Galli Bevilacqua Making abortion rare and safe Duff Gillespie New and underused technologies to reduce maternal mortality Vivien Davis Tsu* Forced migrants--turning rights into reproductive health Linda A Bartlett, Susan Purdin, Therese McGinn Correspondence

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The Nobel prize for MRI: a wonderful discovery and a sad controversy Paul Dreizen Erythropoietin to treat anaemia in patients with head and neck cancer *Johannes H A M Kaanders, Albert J van der Kogel Public health implications of world trade negotiations R.Adlung;J-P Unger and others Inguinal and incisional hernias William Silen Too brief News in brief Thomas Finucane Tactile stimulation of insoles and balance control in elderly people Danik Lafond, Laurence Mouchnino, *François Prince The perils of CPOE Morton H Field Inappropriate aggression Norman M Kaplan DEPARTMENT ERROR Schott JM,Harkness k, barnes j, DELLA Rocchetta Al, .Amnesia,cerebral atrophy, and autoimmunity,Lancet 2003:361:1266 Metzger ML,Howard SC, Fu LC, Outcome of childhood acure lymphoblastic leukaemia in resource poor countries, lancet 2003;362:706-08 Obituary Roger Robinson Mark Henderson Dissecting room Physician writers Jerome Groopman The hyper-regulation of research Jon F Merz Integrating obstetrics and gynaecology into "women's health" Caroline De Costa Websites inbrief A prescription for gender, health, and human rights Rachel Jewkes Tackling pregnancy-related death and injury Sarah Ramsay Lifeline Mahmoud F Fathalla Historical inevitability Druin Burch TEN MOST WANTED Statin editorial most wanted October, 2003 Clinical picture Giant coronary aneurysms D A Sarkar, E E J Smith, S J Brecker

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VOL. 363, NO. 9403, JANUARY 10; 2004
Editorial Poliomyelitis-eradication initiative's wider lessons Commentary Childhood stunting: measuring and stemming the staggering costs of inadequate water and sanitation Rebecca Dillingham, *Richard L Guerrant Air pollution, oxidative stress, and allergic response F J Kelly, *T Sandström Coagulation, inflammation, and pregnancy complications Galit Sarig, *Benjamin Brenner The Surgeon General's report on smoking and health 40 years later: still wandering in the desert *Alan Blum, Eric Solberg, Howard Wolinsky Articles Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome [Summary] [Full Text] [PDF] Y Guan, J S M Peiris, B Zheng, L L M Poon, K H Chan, F Y Zeng, C W M Chan, M N Chan, J D Chen, K Y C Chow, C C Hon, K H Hui, J Li, V Y Y Li, Y Wang, S W Leung, K Y Yuen, F C Leung ZAP-70 expression and prognosis in chronic lymphocytic leukaemia Jenny A Orchard, Rachel E Ibbotson, Zadie Davis, Adrian Wiestner, Andreas Rosenwald, Peter W Thomas, Terry J Hamblin, Louis M Staudt, David G Oscier Effect of water and sanitation on childhood health in a poor Peruvian peri-urban community William Checkley, Robert H Gilman, Robert E Black, Leonardo D Epstein, Lilia Cabrera, Charles R Sterling, Lawrence H Moulton Mechanisms of disease 119 Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study [Summary] [Full Text] [PDF] Frank D Gilliland, Yu-Fen Li, Andrew Saxon, David Diaz-Sanchez Case report A prisoner with acute renal failure Doris Chan, R Sinniah, Ashley Irish Research letters Persistence of impaired pancreatic ß-cell function in children treated for acute lymphoblastic leukaemia Angelika Mohn, Alessandro Di Marzio, Rita Capanna, Giuseppe Fioritoni, Francesco Chiarelli Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage Stephen Tong, Budi Marjono, David A Brown, Sheila Mulvey, Samuel N Breit, Ursula Manuelpillai, Euan M Wallace 93 94 95 96 97




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News Iranian government draws up plans to rebuild Bam Khabir Ahmad Preventing pregnancy malaria Michael McCarthy China culls wild animals to prevent new SARS threat Jonathan Watts Flu jab shortage in Japan puts elderly at risk Justin McCurry FDA issues alert on ephedra supplements in the USA Roxanne Nelson India bans tobacco advertising and smoking in public places Dinesh C Sharma EC grant helps counter Chechen refugee-camp Tom Parfitt Space agency donates satellites to help study Ebola Xavier Bosch NEWS IN BRIEF Italian health bill to overhaul management of NHS hospitals Gareth Carpenter reporting from Lecce, Italy Seminar Infective endocarditis Philippe Moreillon, Yok-Ai Que Review Malaria vaccine developments Vasee S Moorthy, Michael F Good, Adrian V S Hill Public health Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies WHO expert consultation* Correspondence Dried blood spot technology for CD4+ T-cell counting *Howard M Shapiro, Francis F Mandy, Tobias F Rinke de Wit, Paul Sandstrom Spreading the word, but not too thinly *Anthony Howell, C Kent Osborne, Louis Mauriac Practical strategies to combat biopiracy Sue Lawrence, *Jolene Skordis Neutralising antibodies against interferon beta in multiple sclerosis *Gavin Giovannoni, Florian Deisenhammer Health of thalidomide victims and their progeny William McBride Marketing ALLHAT Lionel Opie Artificial neural networks in predicting outcome of gastrointestinal haemorrhage *Dominique Benoit, Johan Decruyenaere, Pieter Depuydt, Kirsten

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Colpaert International register of trial acronyms *Santhanam Sundar, Pat Lawton Doctor performance and public accountability *Sue Osborn, Susan Williams Expiry-date tampering *Jeremy N Day, Tran Tinh Hien, Jeremy Farrar Obituary William W Montgomery Ivan Oransky Dissecting room Where now for problem based learning? Jillian Morrison A pill for everything Martha B Holstein Religio Medici Thomas Sherwood Ambulances and curfews: delivering health care in Palestine J Jaime Miranda AIDS in India Lalit Dandona Websites in brief M Larkin Support M Fitzpatrick The gender gap C. Goodwin Clinical picture The Y-Y paradox Chittaranjan S Yajnik, John S Yudkin

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VOL.363, NO. 9404, JANUARY 17; 2004
Editorial 2004 US election campaign: health at home and Commentary Schistosoma japonicum: modern tools for an ancient *Donato Cioli, Piero Liberti Treatment of Guillain-Barré syndrome with corticosteroids: lack of benefit? Richard A C Hughes Physical activity and obesity James Hill The ß-agonist controversy revisited Ian P Hall Research and development costs for drugs T Lynn Riggs Articles Sudden unexplained infant death in 20 regions in Europe: case control study 179 180 181 182 183 184 185

R G Carpenter, L M Irgens, P S Blair, P D England, P Fleming, J Huber, G Jorch, P Schreuder Effect of methylprednisolone when added to standard treatment with intravenous immunoglobulin for Guillain-Barré syndrome: randomised trial R van Koningsveld, P I M Schmitz, F G A van der Meché, L H Visser, J Meulstee, P A van Doorn, for the Dutch GBS study group* Prediction of total and hip fracture risk in men and women by quantitative ultrasound of the calcaneus: EPIC-Norfolk prospective population study Kay-Tee Khaw, Jonathan Reeve, Robert Luben, Sheila Bingham, Ailsa Welch, Nicholas Wareham, Suzy Oakes, Nicholas Day Mechanisms of disease Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock [Full Text] [PDF] Nazima Pathan, Cheryl A Hemingway, Ash A Alizadeh, Alick C Stephens, Jennifer C Boldrick, Emmanuelle E Oragui, Colm McCabe, Steven B Welch, Adeline Whitney, Peter O'Gara, Simon Nadel, David A Relman, Sian E Harding, Michael Levin Case report Congestive heart failure and a swollen breast Jae Hun Jung, Pil-Ki Min, Yong-Wha Moon, Won Heum Shim Research letters Total energy expenditure and physical activity in young Scottish children: mixed longitudinal study [Summary] [Full Text] [PDF] J J Reilly, D M Jackson, C Montgomery, L A Kelly, C Slater, S Grant, J Y Paton Proportion of tuberculosis transmission that takes place in households in a high-incidence area [Summary] [Full Text] [PDF] Suzanne Verver, Robin M Warren, Zahn Munch, Madalene Richardson, Gian D van der Spuy, Martien W Borgdorff, Marcel A Behr, Nulda Beyers, Paul D van Helden News Polio-endemic countries pledge to boost eradication efforts in 2004 John Zarocostas Canada's new prime minister vows to cut surgery wait lists Paul Webster WHO praises Bam response but warns of disease John Zarocostas FDA demands more information about breast implants Alicia Ault Many countries not on target to reach millennium John Zarocostas Japan steps up SARS plans Justin McCurry EU deplores US execution of mentally ill prisoner Faith McLellan Violence prevention receives international attention




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Khabir Ahmad NEWS IN BRIEF Ugandan officials negotiate Global Fund grants Charles Wendo reporting from Kampala Seminar Cholera David A Sack, R Bradley Sack, G Balakrish Nair, A K Siddique Rapid review Wet markets--a continuing source of severe acute respiratory syndrome and influenza? Robert G Webster Viewpoint WHO, the Global Fund, and medical malpractice in malaria treatment Amir Attaran, Karen I Barnes, Christopher Curtis, Umberto d'Alessandro, Caterina I Fanello, Mary R Galinski, Gilbert Kokwaro, Sornchai Looareesuwan, Michael Makanga, Theonest K Mutabingwa, Ambrose Talisuna, Jean François Trape, William M Watkins Correspondence Intravenous fluids for seriously ill children *Malcolm A Holliday, William E Segar, Aaron Friedman, Russell Chesney, Laurence Finberg HIVNET 012 and Petra Chris P Hudson Thought for food in the Philippines *Shoko Miura, Masamine Jimba, Susumu Wakai Treatment of multidrug-resistant tuberculosis in Russian prisons *Dominique Lafontaine, Andrei Slavuski, Natalia Vezhnina, Oleg Sheyanenko Possible cases of sexual and congenital transmission of sleeping sickness G Rocha, A Martins, *G Gama, F Brandão, J Atouguia El Niño and health J Jaime Miranda The hidden patient Andrew Al-Adwani Energy intake and obesity in Japanese patients with type 2 diabetes Hirohito Sone, Yukio Yoshimura, Hideki Ito, Yasuo Ohashi, *Nobuhiro Yamada, for the Japan Diabetes Complications Study Group Underestimation of allergies in elderly patients *Stefan Wöhrl, George Stingl Lyme borreliosis Lorenzo Cerroni Sonography-guided injection of botulinum toxin in children with cerebral palsy *Steffen Berweck, A Sebastian Schroeder, Urban M Fietzek, Florian Heinen

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20 most-cited countries in clinical medicine ranked by population size *Alec Coppen, John Bailey OBITUARY Paul Janssen I Oransky Dissecting room Tenley Albright Marilynn Larkin A celebration of women in US medicine Diane K Shrier Interactive anatomy Ana Marusic A guide to chemical and drug-induced kidney damage John Firth Hearts and farms: a multifactorial view of coronary artery disease Jolanda M A Boer Lifeline Bankole A Johnson Molluscs and fimbriae Druin Burch

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VOL. 363, NO. 9405, JANUARY 24; 2004
Editorial Avian influenza: the threat looms The Lancet Commentary Should prenatal diagnostic testing be offered to all pregnant women on economic grounds? *Stavros Petrou, Miranda Mugford Burn scars: a new cause of vitamin D deficiency? Dominique Garrel Retrovirus infection as a trigger for primary biliary cirrhosis? *Raoul Poupon, Renée Eugénie Poupon The Lancet's series on health-systems research: a call for papers *Andy Haines, Cesar Victora, Richard Horton "Personal account": a new feature from the patient's perspective *Richard Lane, Faith McLellan, Joe Santangelo Articles Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review Jeffrey M Peppercorn, Jane C Weeks, E Francis Cook, Steven Joffe Doubling the dose of inhaled corticosteroid to prevent asthma exacerbations: randomised controlled trial T W Harrison, J Oborne, S Newton, A E Tattersfield Cost utility of prenatal diagnosis and the risk-based threshold Ryan A Harris, A Eugene Washington, Robert F Nease Jr, Miriam Kuppermann Mechanisms of disease 257 258 259 260 261 262 263 271 276

Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria Trine Staalsoe, Caroline E Shulman, Judith N Bulmer, Ken Kawuondo, Kevin Marsh, Lars Hviid Case report Genetics in reverse Patrick F Chinnery, Niall E F Cartlidge, Stephen Tennant, Daniel Birchall, Su A R Stenhouse Research letters Synthesis of vitamin D in skin after burns Gordon L Klein, Tai C Chen, Michael F Holick, Craig B Langman, Heather Price, Mario M Celis, David N Herndon Group B streptococcal disease in UK and Irish infants younger than 90 days Paul T Heath, Gail Balfour, Abbie M Weisner, Androulla Efstratiou, Theresa L Lamagni, Helen Tighe, Liam A F O'Connell, Mary Cafferkey, Neville Q Verlander, Angus Nicoll, A Christine McCartney, on behalf of the PHLS GBS Working Group News UN urges broadcasters to air AIDS programmes Hannah Brown Shopping 'til we drop Michael McCarthy Six babies die in Russia from hospital-acquired infection Tom Parfitt Spanish editor sued over rofecoxib allegations Xavier Bosch Australian drugs scheme threatens free-trade talks David Fickling Thai HIV vaccine trial prompts angry exchanges Kathleen Nelson IOM calls for universal health coverage by 2010 Alicia Ault Suicide rates rise among soldiers in Iraq Roxanne Nelson NEWS IN BRIEF Drive to improve patient choice within the UK NHS Malcolm Dean reporting from London Seminar Postpartum psychiatric disorders Ian Brockington Personal Account Motherhood--a potential killer Marina Green Review Communicating sad, bad, and difficult news in medicine Lesley Fallowfield, Valerie Jenkins



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Public health Scaling-up treatment for HIV/AIDS: lessons learned from multidrugresistant tuberculosis Rajesh Gupta, Alexander Irwin, Mario C Raviglione, Jim Yong Kim Hypothesis Bifidobacterium lipoteichoic acid and false ELISA reactivity in aspergillus antigen detection Monique A S H Mennink-Kersten, Rocus R Klont, Adilia Warris, Huub J M Op den Camp, Paul E Verweij Correspondence Rosuvastatin-warfarin drug interaction Michael Barry Politics in medical journals Jim Whiting What are health and human rights? Sofia Gruskin Quality of medical education in Mexico *Rafael Santana-Davila, Cristina Martinez Oral prednisolone for viral wheeze in young children *Miles Weinberger, Richard Ahrens Effects of different blood-pressure-lowering regimens on major cardiac events *Hans-Michael Steffen, Ulrich Toex, Rainer Kolloch Confusion over benefits of hormone replacement therapy C A Huntingford Obituary James Dorman Weaver Ivan Oransky Dissecting room If she were your daughter, what would you do? Joal Hill Harnessing globalisation as a "force for good" Lesley Morrison Terrorism and disaster in the 21st century A C McFarlane Websites in brief M Larkin Making medicine's difficult choices Ivan Oransky Food fads Citizen Copito X Bosch Uses of error Clinical, teaching, and research misunderstandings John P A loannidis



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VOL. 363, NO. 9406, JANUARY 31;200

Who pays in the obesity war The Lancet Commentary Risk of cancer from diagnostic X-rays *Peter Herzog, Christina T Rieger Liver-iron assay by MRI Diego R Martin Arterial abnormalities in children with familial hypercholesterolaemia Olli T Raitakari Down with bedrails? Shaun T O'Keeffe Highs and lows of cannabis David Sharp Articles Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries Amy Berrington de González, Sarah Darby Rehabilitation therapy services for stroke patients living at home: systematic review of randomised trials Outpatient Service Trialists* Non-invasive assessment of hepatic iron stores by MRI Y Gandon, D Olivié, D Guyader, C Aubé, F Oberti, V Sebille, Y Deugnier Mechanisms of disease Insulinomas and expression of an insulin splice variant Alexandra H Minn, Mark Kayton, Dominique Lorang, Steven C Hoffmann, David M Harlan, Steven K Libutti, Anath Shalev Case report Venous unresponsiveness R Bernstein, S Futterer Research letters Arterial intima-media thickness in children heterozygous for familial hypercholesterolaemia Albert Wiegman, Eric de Groot, Barbara A Hutten, Jessica Rodenburg, Johan Gort, Henk D Bakker, Eric J G Sijbrands, John J P Kastelein Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy Ross T Murphy, Jens Mogensen, Anthony Shaw, Toru Kubo, Sian Hughes, William J McKenna News Asian nations step up action to curb spread of avian influenza Jonathan Watts Democrat presidential hopefuls unveil plans for US health care Faith McLellan French health system on verge of collapse, says report Xavier Bosch

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US FDA increases scrutiny of tissue banks Alicia Ault AIDS drugs being sold illegally on market stalls in Kenya Samuel Siringi UNICEF calls for efforts to eradicate vitamin deficiency John Zarocostas Deaths in UK prisons are due to overcrowding, says report Rachael Davies NEWS IN BRIEF NIH names panel to probe conflict-of-interest charges Daniel Greenberg reporting from Washington Seminar Migraine Stephen D Silberstein Rapid review Imaging cerebral atrophy: normal ageing to Alzheimer's disease Nick C Fox, Jonathan M Schott Viewpoint Disclosure of genetic tests for health insurance: is it ethical not to? Nick Raithatha, Richard D Smith Correspondence Response to accusations of medical malpractice by WHO and the Global Fatoumata Nafo-Traoré The Lancet's call to ban smoking in the UK T G F Lord Preoperative assessment *G Geldner, M Christ, H Wulf Investing in children *Roberto Bertollini, Viv Taylor Gee Effect of US policies on women's health worldwide Amy E Pollack, *Rachael N Pine, Christina Wypijewska Risk of stillbirth after previous caesarean section *Jennifer J Kurinczuk, Ron Gray, Peter Brocklehurst Are housestaff heliotropic? *Douglas L Riegert-Johnson, Vanessa Z Riegert-Johnson Obituary Margaret Thaler Singer Ivan Oransky Dissecting room Rita Charon Rita Charon The consequences of mutations in mitochondrial DNA Anthony H V Schapira Fashions and foibles in medicine David Weatherall Reproductive health in art Lindsay Edouard

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Lifeline Seth Berkley You don't know where it's been Carol Cooper CLINICAL PICTURE Scimitar syndrome M Riedel and others Uses of error Urine pregnancy test and intrauterine inseminations Mahantesh A Karoshi

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VOL. 364, NO. 9433, AUGUST 7; 2004
Editorial WHO's African regional office must evolve or die How not to grade hospital safety Comment Transfusion transmission of vCJD: a crisis avoided? *Kumanan Wilson, Maura N Ricketts Mean times in transfusion--carrots and sticks for practice in England Mallika Sekhar Show me the money--immunosuppression in kidney transplantation George W Burke, Gaetano Ciancio When to deliver the stunted fetus? David A Grimes Myths about spider envenomations and necrotic skin lesions Richard S Vetter Autism--prenatal insults or an epiphenomenon of a strongly genetic disorder? *Christina M Hultman, Pär Sparén Time for the ghosts to take on physical form Adam Jacobs The Wakley Prize 2004 Astrid James World Report The law of consent Stephen Pincock Organ failure Carmiola Ionescu Perspectives Book: It's my baby and I'll try if I want to W P Sharpe In brief H M Salihu; L.Morrison Historical keywords: Lifestyle Rhodri Hayward Lifeline: Frederick "Skip" M Burkle, Jr 475 476 477 479 481 483 484 485 487 488 489 491 493 494 495 495

Obituary George Widmer Thorn Ivan Oransky Correspondence Adolescent health Fawad Aslam NEOPAIN: a question of survival Christoph Pechlaner Drug intervention trials in sepsis Cristiane Ritter, Michael Andrades, Adalisa Reinke, José Cláudio F Moreira, *Felipe Dal-Pizzol Arguments for live flavivirus vaccines *Joachim Hombach, Ichiro Kurane, David Wood hGISA: seek and ye shall find *Robin A Howe, Timothy R Walsh Herpes simplex virus type 2 and recurrent meningitis *Nicholas Davies, Julian Tang, Katherine Nora Ward Pituitary apoplexy presenting as chemical meningitis R Brouns, R Crols, S Engelborghs, *P P De Deyn Povidone-iodine for herpes zoster Frank Shann Articles Mycophenolate mofetil versus azathioprine for prevention of acute rejection in renal transplantation (MYSS): a randomised trial Giuseppe Remuzzi, Mariadomenica Lesti, Eliana Gotti, Maria Ganeva, Borislav D Dimitrov , Bogdan Ene-Iordache, Giulia Gherardi, Donato Donati, Maurizio Salvadori, Silvio Sandrini, Umberto Valente, Giuseppe Segoloni, Georges Mourad, Stefano Federico, Paolo Rigotti, Vito Sparacino, Jean-Louis Bosmans, Norberto Perico, Piero Ruggenenti, for the MYSS Study Group* Infant wellbeing at 2 years of age in the Growth Restriction Intervention Trial (GRIT): multicentred randomised controlled trial The GRIT study group* Novel methods for disinfection of prion-contaminated medical devices Guillaume Fichet, Emmanuel Comoy, Christelle Duval, Kathleen Antloga, Capucine Dehen, Aurore Charbonnier, Gerald McDonnell, Paul Brown, Corinne Ida Lasmézas, Jean-Philippe Deslys Research Letters Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient Alexander H Peden, Mark W Head, Diane L Ritchie, Jeanne E Bell, James W Ironside Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood Luisa Gregori, Nancy McCombie, Douglas Palmer, Paul Birch, Samuel O Sowemimo-Coker, Antonio Giulivi, Robert G Rohwer

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Clinical Picture Intranuclear biotin E Marbaix, F Waignein, P Camby, I Lopez de la Osa Escribano, P Bernard, C Sempoux Seminar Kawasaki syndrome Jane C Burns, Mary P Glodé Hypothesis Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation Mervyn Singer, Vincenzo De Santis, Domenico Vitale, William Jeffcoate Viewpoint Necrotic arachnidism: the mythology of a modern plague Geoffrey K Isbister Case Report A puzzling case of transient global amnesia P Bonnet, P Niclot, F Chaussin, M Placide, MP Debray, A Fichelle Fast track article


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VOL. 364, NO. 9434, AUGUST 14; 2004
Editorial More doctors needed, without discrimination National strategies wanted to plug the brain drain Comment Potential funding crisis for the Radiation Effects Research Foundation *Mark P Little, Maria Blettner, John D Boice, Jr, Bryn A Bridges, Elisabeth Cardis, Monty W Charles, Florent de Vathaire, Richard Doll, Kenzo Fujimoto, Dudley Goodhead, Bernd Grosche, Per Hall, Wolfgang F Heidenreich, Peter Jacob, Suresh H Moolgavkar, Colin R Muirhead, Ohtsura Niwa, Herwig G Paretzke, Richard B Richardson, Jonathan M Samet, Yasuhito Sasaki, Roy E Shore, Tore Straume, Richard Wakeford Are drug-eluting stents a panacea for patients with coronary heart disease? *Joachim Schofer, Michael Schlüter Intrapartum prevention of meconium aspiration syndrome Marina Cuttini Progress in research into systemic sclerosis Bashar Kahaleh Health-care provision and the path out of poverty *Shona Wynd, David N Durrheim COPD--a neglected disease *Peter J Barnes, Sabine Kleinert Has vancomycin-resistant Staphylococcus aureus started going it alone? *Keiichi Hiramatsu, Longzhu Cui, Kyoko Kuwahara-Arai Oesophageal cancer: a view over overviews Alastair J Munro 555 556 557

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Lancet International Fellowships 2005 Astrid James World Report Left by the lakeside Mike Ceaser When blue babies grow up Wendy Wolfson Perspectives Book: On your marks, get set . . . modify Leigh Turner In brief K Morris; M MMcCarthy On reflection: The perils of myopia Richard Lane Lifeline: Stephen Minger Obituary Francis Harry Compton Crick Stephen Pincock Correspondence Questions about SSRI antidepressant drug regulation Alastair Hay Importance of disclosure of patent applications Beverly Rockhill Severe acute disseminated toxoplasmosis *Philippe Bossi, François Bricaire Cuban doctors Imti Choonara Paraoxonase polymorphisms and coronary heart disease *P N Durrington, B Mackness, M I Mackness Genetics of stroke C John Dickinson Famous Hungarian physicians András Mogyorósi Sir Percivall Pott, Sir James Paget, and soot cancer of the hand Keith Denkler Articles A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents Mohan N Babapulle, Lawrence Joseph, Patrick Bélisle, James M Brophy, Mark J Eisenberg Risk of developing a mitochondrial DNA deletion disorder Patrick F Chinnery, Salvatore DiMauro, Sara Shanske, Eric A Schon, Massimo Zeviani, Caterina Mariotti, Fanco Carrara, Anne Lombes, Pascal Laforet, Helène Ogier, Michaela Jaksch, Hanns Lochmüller, Rita Horvath, Marcus Deschauer, David R Thorburn, Laurence A Bindoff, Joanna

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Oropharyngeal and nasopharyngeal suctioning of meconium-stained neonates before delivery of their shoulders: multicentre, randomised controlled trial [Summary] [Full Text] [PDF] Nestor E Vain, Edgardo G Szyld, Luis M Prudent, Thomas E Wiswell, Adriana M Aguilar, Norma I Vivas, for the Meconium Study Network* Mechanisms of Disease Defective vasculogenesis in systemic sclerosis Masataka Kuwana, Yuka Okazaki, Hidekata Yasuoka, Yutaka Kawakami, Yasuo Ikeda Research Letters Postemergency health services for refugee and host populations in Uganda, 1999-2002 Christopher Garimoi Orach, Vincent De Brouwere Seminar Burden and clinical features of chronic obstructive pulmonary disease (COPD) Romain A Pauwels, Klaus F Rabe Review Faecal incontinence in adults Robert D Madoff, Susan C Parker, Madhulika G Varma, Ann C Lowry Viewpoint Further from Washington: can Celtic UK renew the NHS? Julian Tudor Hart Case Report A man with diabetes and heart failure Robin Nijveldt, Erik H Serné, Jan M Sepers, J Antonie Maassen, Jan Hein Cornel, Alf E R Arnold





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VOL. 364, NO. 9435, AUGUST 21; 2004
Editorial How complicit are doctors in abuses of detainees? Ejecting the FDA from the courtroom Comment A coxib a day won't keep the doctor away *Eric J Topol, Gary W Falk Statins for all patients with type 2 diabetes: not so soon Abhimanyu Garg Tonsillectomy technique--tradition versus technology Malcolm Hilton Nosocomial bacteraemia caused by Staphylococcus aureus *Pierre Vaudaux, Jacques Schrenzel Women undergoing termination of pregnancy should be screened for gestational trophoblastic neoplasia Benjamin Piura Unhealthy airports Jangu Banatvala Rabies transmission from organ transplants in the USA 637 638 639 641 642 644 645 646 648

*Bernhard Dietzschold, Hilary Koprowski Is repeated caesarean section a consequence of elective caesarean section? *Eddie F C Murta, Rosekeila S Nomelini World Report Fat of the land Pelle Neroth Disease and hunger in Sudan Hannah Brown Perspectives Book: Reclaiming dignity from despair in Alzheimer's disease Martha B Holstein In brief H East, C A Brown; M T White Ten most wanted: Statins: friend or foe? Lifeline: Kamran Abbasi Obituary Edward B Lewis Terrell Tannen Correspondence Practicalities of consent *Ian A Laing, Neil McIntosh Use of selective serotonin reuptake inhibitors in childhood depression [Full Text] [PDF] *Tamar Wohlfarth, Frits Lekkerkerker, Barbara van Zwieten Free sugars and human health Charles W Baker Outdoor air pollution: the effects of ozone *Alastair C Lewis, James D Lee, Lucy J Carpenter A positive outcome *Kerry Davies, An Sophat Hospital versus home Patrick F James Articles Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial Thomas J Schnitzer, Gerd R Burmester, Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gitton, Gerhard Krammer, Bernhard Mellein, Patrice Matchaba, Alberto Gimona, Christopher J Hawkey, on behalf of the TARGET Study Group* Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial Michael E Farkouh, Howard Kirshner, Robert A Harrington, Sean Ruland, Freek W A Verheugt, Thomas J Schnitzer, Gerd R Burmester,


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Eduardo Mysler, Marc C Hochberg, Michael Doherty, Elena Ehrsam, Xavier Gitton, Gerhard Krammer, Bernhard Mellein, Alberto Gimona, Patrice Matchaba, Christopher J Hawkey, James H Chesebro, on behalf of the TARGET Study Group* Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial Helen M Colhoun, D John Betteridge, Paul N Durrington, Graham A Hitman, H Andrew W Neil, Shona J Livingstone, Margaret J Thomason, Michael I Mackness, Valentine Charlton-Menys, John H Fuller, on behalf of the CARDS investigators Tonsillectomy technique as a risk factor for postoperative haemorrhage National Prospective Tonsillectomy Audit* Research Letters Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers [Summary] [Full Text] [PDF] Heiman F L Wertheim, Margreet C Vos, Alewijn Ott, Alex van Belkum, Andreas Voss, Jan A J W Kluytmans, Peter H J van Keulen, Christina M J E Vandenbroucke-Grauls, Marlene H M Meester, Henri A Verbrugh Routine terminations of pregnancy--should we screen for gestational trophoblastic neoplasia? Michael J Seckl, Roopinder Gillmore, Marianne Foskett, Neil J Sebire, Helene Rees, Edward S Newlands Clinical Picture Babies and batteries Jolita Bekhof, Obbe Norbruis, Rene Scheenstra, Frederik Dikkers, Ries de Langen, Willemien de Weerd Seminar Pathophysiology of airflow limitation in chronic obstructive pulmonary disease James C Hogg Rapid Review Pathogenetic mechanisms of parkin in Parkinson's disease Nobutaka Hattori, Yoshikuni Mizuno Health and Human Rights Abu Ghraib: its legacy for military medicine Steven H. Miles Case Report A red tattoo and a swordfish supper Daisuke Tsuruta, Junko Sowa, Natsuko Higashi, Hiromi Kobayashi, Masamitsu Ishii Fast track article


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