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					                          ISRAEL CANCER RESEARCH FUND
                          International Executive Office
                          1290 Avenue of the Americas  Suite 550  New York, NY 10104
                          Tel: (212) 969-9800  Fax: (212) 969-9822  Toll Free: (888) 654-ICRF [4273]
                  E-mail completed applications to:

              (Postdoctoral Fellowships/Project Grants/RCDAs/CRCDAs/Professorships)

GENERAL INSTRUCTIONS - Please Read All Of The Following Carefully:

● Applications must be completed in standard American or British English. If English is not your first
  language, we strongly urge that the application be reviewed and corrected by someone perfectly
  fluent in grammatical, idiomatic English. You should not assume that the reviewers, each of whom
  will have to read 10 or more grant applications, will be prescient, patient or more than usually
  understanding by the time they read your application. Stated simply, this means that your chances
  of having your application understood will be greatly increased if you follow the suggested approach.
  Do not use abbreviations without definition, unless they are obvious to all (e.g., M.D., DNA).

● Before filling out the application, read the general policies governing the type of award for which you
  are applying. Follow all directions carefully.

● Fill out each item in each section completely. Make sure your name appears in the upper right-hand
  corner of every page.

● The entire text of the application should be in the Arial font. On the application form, the font size
  must not be smaller than Arial 10 point, 6 lines per vertical inch. For the Research Plan, the font size
  must not be smaller than Arial 11 point with half-inch margins all around. (Only figure legends may
  be in a different font and/or smaller point size.)

● Do not alter the borderlines on the application form. Please note that the actual application form
  consists of five (5) pages, exclusive of the checklist (prepared for 8.5” x 11” paper with .25”
  margins, but A4 paper can be used). If yours is more than 5 pages, then you did not fill it out
  correctly and must reformat. (Please view or print the PDF version of the application form so that
  you can see the correct layout.)

● Please submit one (1) copy of your application to us electronically as an E-mail attachment prior to
  the deadline in either MSWord or PDF format to: Make sure to include your
  C.V. and publication list, and all other appended materials. No printed copies are necessary. One
  electronic file of the full proposal is preferable, but if the file is too large to E-mail, it can be sent in
  several smaller files. No supplemental materials will be accepted after the deadline unless
  requested by ICRF.

  Failure to follow any of these instructions precisely will result in rejection of the application
  prior to scientific review and forfeit of a chance to compete for an award in the current year.

ICRF                                               1/6                                                  (8/08)

These must be followed precisely. Read these instructions, item by item, as you fill in each
section of the application form. If you have any questions, telephone us or send an E-mail
message to:

Please Note: A Project Grant Application from Co-P.I.'s should contain a separate first and second
page (Items 1-20) for each investigator as well as their respective C.V. and publication lists.

1.     Type: The type of grant for which you are applying must be indicated by placing an "X" in the
       appropriate box. Mark one (1) box only. The ICRF reserves the right to reclassify the
       application, but will do so very rarely. You are primarily responsible for the proper classification
       of your application. (However, if an RCDA application is received from a clearly ineligible
       applicant, the applicant will be asked to shorten the application in order to be eligible for a
       Project Grant.)

       As a general guide, note that the type of grant is dependent partly on the number of years past
       the terminal doctorate:  Fellowship:         1 - 3 years
                                Project Grant:      3 or more years
                                RCDA:               within 5 years of first independent position
                                CRCDA:              5 - 12 years
                                Professorship:      8 or more years
       Only one (1) grant application per person will be accepted for each submission deadline.

2.     Date of application: Self-explanatory.

3.     Name: Last name first in CAPITAL LETTERS, first and middle names in Upper and lower case
       letters. Indicate degree (e.g., M.D., Ph.D., etc.).

3a.    Your Signature is required in addition to your printed name. Your signature indicates your
       agreement to abide by ICRF’s rules and regulations if an award is made to you.

4.     Sex: Check either "M" for Male or "F" for Female.

5.     Permanent Address: This is an address at which you can always be reached (such as your
       home address).

6.     Work Address: Self-explanatory. Include Telephone, Fax number, and E-mail Address.

7.     Date of Birth: Self-explanatory. Month/Day/Year in that order.

7a.    Age: In years.

8.     Place of Birth: City, State, Country. (e.g., Tel-Aviv, Israel or Newark, New Jersey, USA).

9.     Title of Project: Do not exceed the space provided – Maximum 90 characters. Do not use a
       font size smaller than Arial 10 point.
ICRF                                                   2/6                                          (8/08)
10.    Put an "X" in the appropriate box(es). See Policies Governing Awards. Attach appropriate
       assurances of compliance from the institutional authorities (which must be written in English!).
       The review date should be recent; certification is invalid if the review date precedes the
       submission date by more than one year.

11.    Period of Award: Period of time requested for this award. (e.g., From: September 1, 2009, To:
       August 31, 2011.)

12.    Location of Proposed Project: Self-explanatory. (Must be in Israel.)

13.    Institution’s Financial Officer: Self-explanatory.

14.    Person Authorized to Sign for Institution: This should be the president, director, or other in
       authority. This signature indicates willingness of the institution to abide by all of the rules and
       regulations of the ICRF.

15.    Please indicate whether you have ever received ICRF award(s).

15a.   If you have answered "yes" in Item 15, place an "X" in the appropriate box(es).

15b.   Indicate the inclusive years during which you were the recipient of award(s).

15c.   Put an "X" in the "yes" box if you are applying for continuation of a grant currently funded.
       (For example: you are applying for a Project Grant after having completed a Fellowship, or you
       are applying for a Project Grant to commence upon completion of an existing grant.)

16.    Full C.V. and Publication List: This must be included. Attach your C.V. and publication list (as
       well as those of any other personnel with a doctoral degree) after the reference section of your
       research plan. This can be in any format (for example, an NIH biosketch), but the publication
       list must include co-authors' names, title of paper, date of publication, and inclusive pages.

17.    For CRCDA Applicants Only: On a separate page, indicate the individual(s) — whether in your
       or in other institutions — willing to provide training (mentoring) or to participate in the project by
       entering patients in your study. Include letter(s) from these individual(s) stating these facts.
       Attach this information after your publication list.

18A.   For POSTDOCTORAL FELLOWSHIP Applicants Only: Indicate the name and title of your
       sponsor and attach a letter of recommendation and C.V./publication list from your sponsor. This
       letter should include a statement on how this training will prepare you for a career. The
       application will not be considered without this. Remember, the Fund will not approve your
       application if the proposed project will be conducted in the same laboratory in which you
       completed your doctoral degree.

18B.   For POSTDOCTORAL FELLOWSHIP Applicants Only: Type the names, titles, and addresses
       of two scientific references who will submit letters about you to us. These letters must be
       available for review prior to the deadline.

ICRF                                                    3/6                                           (8/08)
19.    Facilities Available: State floor space available to you in sq.m. or sq.ft. Indicate the nature of
       the space (i.e., office, laboratory, radiation therapy room). List major items of equipment
       available for your exclusive use. List shared facilities separately (e.g., liquid scintillation
       counter, 20% time).

20.    Present Research Support Available: This item must be completed carefully and fully.
       Please Note: Providing this information will not necessarily preclude you from receiving an
       award, but failure to include it may result in rejection of your application.
       ● First, indicate and list each grant of which you are Principal Investigator as (PI). State
            funding organization, grant title, % full time equivalents (FTE) of your time, total amount in
            US Dollars ($), total duration of awards, in that order. Example: (PI) NIH, Cholesterol levels
            in blood of fatted calves, 20%, $125,000 12/01/07-11/30/10 (MO/DAY/YR).
       ● Next, indicate and list each grant of which you are a Co-Investigator as (CI). State funding
            organization, grant title, principle investigator, %FTE of your time, total amount in dollars
            ($), total duration of award. Example: (CI) Volkswagen Stiftung, Molecular biology of ugly
            ducklings. Leshek Walenza, PI, 15%, $300,000. 01/02/08-12/31/10 (MO/DAY/YR).
       ● Then, indicate and list, in the same format, all applications currently under consideration as
       If you have no current support and/or submitted applications, please indicate "none" where

21.    Proposed Budget: Present this in some detail for the first year. Additional years are not to
       exceed one for a Postdoctoral Fellowship or Project Grant and two for RCDAs, CRCDAs, and

21A.   Personnel: Names and positions of all personnel must be individually listed and the percentage
       of time to be devoted to the project by each person should be noted, even when salary is not
       requested. If an individual has not yet been selected, please list as ―to be determined.‖ List
       consultants here also, and include letters of intent to collaborate in the appendix. (Please also
       provide in the appendix the C.V. and publication list for all key personnel involved in the project,
       including postdoctoral fellows, research assistants/associates, consultants and collaborators.
       If a project participant has a doctoral degree, then his or her C.V. and publication list
       must be included.)

21B.   Equipment: List separately and justify the need for each item of equipment requested in
       Item 21F on page 4/6.

21C.   Supplies: Group these into major categories (glass and plasticware, chemicals, radioisotopes,
       etc.) If the project involves the use of proprietary drugs, you must include in the
       appendix a letter from the drug manufacturer or supplier indicating that they will have no
       control over publication or dissemination of the results of the study.

21D.   Other: Examples of allowed miscellaneous expenditures include publication costs, computer
       time, equipment maintenance, etc. Please note that the ICRF does not allow its funds to be
       used for overhead, travel, or for work performed outside of Israel. However, travel may
       be permitted for CRCDAs under special circumstances.

21E.   Total: Enter the sum for all years of requested support.

21F.   Budget Additions and Justifications: Provide sufficient information in order to justify all items of
       equipment, the need for personnel, supplies, and any other miscellaneous and/or unusual

ICRF                                                   4/6                                          (8/08)
22.    Relevance to Cancer: Provide a short paragraph of approximately 200 words or less, in non-
       technical language, explaining how your work is relevant to the clinical problem of cancer. (The
       ICRF recognizes that cancer research encompasses a very broad spectrum and that progress
       in cancer control will, therefore, come from taking the broadest possible view, consistent with
       our mission, of what constitutes cancer research.)

23.    Resubmission of an Application: Applications that were not funded may be revised and
       resubmitted. Resubmitted applications will be reviewed in the same detail and compete on an
       equal basis with all other new applications. In this section, please briefly describe what the
       reviewers’ major concerns were and how these concerns have now been addressed. (If the
       reviews of your previous application were generally favorable, then please indicate that as well.)
       If space is not sufficient, then a maximum of one (1) additional page may be attached.

Please note that Items 24a, 24b, and 24c (Specific Aims) must all fit on page 5/6 of the
application form. (Only RCDA, CRCDA & Prof. applications may continue on a second page.)

24a.   Research Plan: Your name, the type of award for which application is being made, the title of
       the application (same as Item 9) and the institution must appear at the top of this page.

24b.   Research Plan Summary: Summary must not exceed the space indicated and be printed in the
       Arial 10 point font or larger. Make sure you underline key words. Emphasize new approaches
       and knowledge to be gained.

24c.   Research Plan in Detail: Include sufficient information to facilitate an effective review without
       reference to any previous application. Be specific and informative and avoid redundancies.
       Reviewers will consider brevity and clarity in the presentation as indicative of an applicant's
       approach to a research objective and ability to conduct a superior program.

       Text should be single-spaced using the Arial 11 point font, 6 lines per vertical inch, with a
       minimum of half-inch margins, formatted for either 8.5‖ x 11‖ or A4 paper size.

       Organize Sections of the RESEARCH PLAN to answer these questions: a) What do you intend
       to do? b) Why is the work important? c) What has already been done? d) How are you going
       to do the work?

       conform to the guidelines on font size, page length, or project scope may impact unfavorably on
       the priority score, or result in the application being returned to the investigator without review.

       Please adhere to the following format:

       ● Specific Aims: State clearly and concisely what the research described in this application is
          intended to accomplish and/or what hypothesis is to be tested. Proposals should be realistic
          in terms of work to be accomplished within the period of time for which support is requested.
          DO NOT EXCEED THE SPACE PROVIDED ON PAGE 5. This section MUST appear on
          page 5/6 (Item 24c) of the application form.

ICRF                                                  5/6                                          (8/08)
       ● Significance:    Briefly sketch the background of the present proposal, critically evaluate
          existing knowledge and specifically identify the gaps that the project is intended to fill. State
          concisely the importance of the research described in this application by relating the specific
          aims to longer-term objectives. DO NOT EXCEED ONE PAGE FOR POSTDOCTORAL

       ● Preliminary Studies: Use this section to provide an account of your preliminary studies
          pertinent to the application and/or any other information that will help to establish the
          experience and competence of the applicant to pursue the proposed project. The titles and
          complete references to appropriate publications and completed manuscripts must be listed,
          and not more than three (3) publications may be submitted as an APPENDIX. DO NOT

       ● Research Design and Methods:           Discuss in detail the experimental design and the
          procedures to be used to accomplish the specific aims of the project. Describe the protocols
          to be used and provide a tentative sequence or timetable for the investigation. Although the
          time estimated should not exceed the term for which support is requested, it is helpful to
          state how this project fits in with your long-term research goals. Include the means by
          which the data will be statistically analyzed and interpreted. Any project that includes
          a planned number of observations, especially clinical trials, must indicate the number
          of subjects or experiments needed for statistical analysis, indicating clearly the
          reasoning for obtaining such numbers. Projects that do not indicate the statistical
          power for a given sample size and/or indicate the probability of finding significance
          will not be considered at all! Describe any new methodology and its advantage over
          existing methodologies. Discuss the potential difficulties and limitations of the proposed
          procedures and alternative approaches for achieving the aims. In a separate subsection,
          point out any procedures, situations, or materials that may be hazardous to personnel and
          the precautions to be exercised.           DO NOT EXCEED THREE PAGES FOR A
          POSTDOCTORAL FELLOWSHIP OR PROJECT GRANT.                             RCDA and CRCDA
          MAY NOT EXCEED 10 PAGES.

       ● References: Cite these in full. This includes first and last pages of articles.

       ● Appendix: Appended materials may include letters of collaboration, copies of publications
          (no more than 3, please!), tables and figures, etc. However, the appendix section should not
          be used to bypass the page limitations.

ICRF                                                   6/6                                          (8/08)

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