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					CURRICULUM VITA NAME: PLACE OF BIRTH: CITIZENSHIP: HOME ADDRESS: Gerardo Raul Vasta Buenos Aires, Argentina United States of America 5687 Phelps Luck Drive Columbia, MD 21045 Phone: (410) 730-9398 Center of Marine Biotechnology, University of Maryland Biotechnology Institute, University of Maryland System Columbus Center 701 E. Pratt Street Baltimore, MD 21202 Phone: (410) 234-8826, -8827; FAX: -8896 E-mail: vasta@umbi.umd.edu Married, two children.

OFFICE ADDRESS:

MARITAL STATUS: UNIVERSITY DEGREES

Doctor in Biochemistry, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina (1978). Doctor in Natural Sciences (Zoology), School of Natural Sciences, National University, La Plata, Buenos Aires, Argentina (1980). Licenciate in Biochemistry, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina (1973). Licenciate in Zoology, School of Natural Sciences, National University, La Plata, Buenos Aires, Argentina (1976). Chemist, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina (1972). POSITIONS HELD Professor [With tenure], Center of Marine Biotechnology, University of Maryland, Baltimore, MD, USA. From June 1997 to the present. Consultant for Research, Department of Biological Sciences, George Washington University, Washington, DC. From June 1996 to the present.

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Faculty Associate (Professor) of the Continuing Education Program, Johns Hopkins University, Baltimore MD. From March 1992 to the present. Visiting Professor, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina, November 2003. Visiting Professor, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina, August 1993. Associate Professor [With tenure], Center of Marine Biotechnology, University of Maryland, Baltimore, MD., USA. From March 1989 to May 1997. Assistant Professor, Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA. 1984-1989. Research Associate, Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC, USA. 1982-1984. Post-Doctoral Fellow, Department of Biochemistry and Molecular Biology of South Carolina, Charleston, SC, USA. 1981-1982. Post-Doctoral Fellow, Department of Laboratory Medicine, Clinical Immunology Section Roswell Park Memorial Institute, Buffalo, NY 1979-1980. Graduate Instructor, Human Anatomy, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1973-1979. Graduate Instructor, Serological Genetics Unit, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1973-1974. Undergraduate Assistant, General Biology, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1970-1972. Undergraduate Assistant, Serological Genetics Unit, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1972. Undergraduate Assistant, General Biology, Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1966. AWARDS, FELLOWSHIPS AND HONORS J. William Fulbright Scholar International Award, United States Department of State, Bureau of Educational and Cultural Affairs and the Council for International Exchange of Scholars (CIES), September-November 2007 Faculty Award, University of Maryland Biotechnology Institute. Presented at the Faculty Awards Ceremony, Governor Calvert House, Annapolis, MD February 2006 1st Prize, Best Poster Competition, Scientific Meeting of the University of Maryland Biotechnology Institute [Wright, A.C., Ahmed, H., Gauthier, J., Silva, A and Vasta, G.R. Cloning and sequencing of cDNA for superoxide dismutases from Perkinsus marinus: Characterization of an iron superoxide dismutase] April 1997. Travel Scholarship. Third International Congress of Comparative Physiology and Biochemistry, Tokyo. Workshop "Invertebrate Defense Mechanisms" organized by Drs. S. Natori and M. Ashida. August 1991. Nuffield Foundation Award, Cooperation Project "Humoral and Cellular Immunity in Invertebrates" P.I.: Prof. Ann Lackie, Department of Biology, Glasgow University, Glasgow, U.K., 1984, 1985.

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Fogarty International Fellowship, Fogarty Institute, National Institutes of Health. Department of Biochemistry, Medical University of South Carolina, Charleston SC, 1981-1983. Post-Doctoral Fellowship. Medical University of South Carolina, Department of Biochemistry, Charleston, SC Scientific Advisor: Professor and Chairman J.J. Marchalonis, 1981. International Fellowship for Scientific Research. National Council of Scientific and Technological Research of Argentina. Roswell Park Memorial Institute, Buffalo, NY Clinical Immunology Section, Department of Laboratory Medicine. Scientific Advisor: Elias Cohen, Ph.D. 1979-1980. National Fellowship for Scientific Research. National Council of Scientific and Technological Research of Argentina, Department of Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. Scientific Advisors: Drs. Alois Bachman and Manuel Escalante. From August 1976-1978. National Fellowship for Scientific Research. National Council of Scientific and Technological Research of Argentina, Department of Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. Scientific Advisor: Prof. Dr. Marcos Palatnik. 1974-1976. Fellowship for Scientific Research. Department of Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. Scientific Advisor: Prof. Dr. Ricardo Weinberg. 1969-1970. Fellowship for University Students. Department of Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. 1966-1969. Honor Award from City County of Mar del Plata, Buenos Aires, Argentina, 1968-1973. RESEARCH INTERESTS Molecular, biochemical and biological aspects of protein-carbohydrate interactions relevant to non-self or cell-cell recognition mechanisms. Function/structure/evolution of innate immune mechanisms in invertebrates (Model organisms: mollusks and tunicates) and ectothermic vertebrates (Model organisms: fish and amphibians). Role of protein carbohydrate interactions in early development (Model organism: C. elegans and zebrafish). Biochemical, molecular and genomic approaches to the study of recognition, signaling, and mechanisms for intracellular survival of protistan parasites (Model system: P. marinus and its host, the eastern oyster). EXTRAMURAL FUNDING ACTIVE FUNDING Grants National Science Foundation, Project Title: “Intracellular Survival of Protistan Parasites: Roles of the Host and Parasite Iron Transporter Sclc11a”. Principal Investigator: G.R.

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Vasta; Co-PI: J.A. Robledo. Funding period: 36 months. Funds awarded: U$S 450,000. (2003-2007NCE). National Institutes of Health, Project Title: “Biological roles of galectins”. Principal Investigator: G.R. Vasta. Co-PIs: J, Du and H. Ahmed. Funding period: 48 months. Funds awarded: US $1,045,500 (2004-2008). National Sea Grant Office, NOAA, DOC. Project Title: “Crassostrea ariakensis as a sink for potential pathogens in Chesapeake Bay”. Principal Investigator: G. R. Vasta. Funding period: 24 months. Funds awarded: U$S 240,000. (2005-2007). National Science Foundation, Project Title: “Organellar targeting, regulation, and biological role(s) of antioxidant enzymes in the protistan parasite Perkinsus marinus” Principal Investigator: G.R. Vasta. Funding period: 36 months. Funds awarded: US $420,000 (2006-2009). National Sea Grant Office, NOAA, DOC. Project Title: “Resistance of Crassostrea ariakensis to Bonamia spp infection” Principal Investigator: G. R. Vasta. Funding period: 24 months. Funds awarded: U$S 210,000. (2005-2007). Fellowships National Institutes of Health, National Research Service Award, Post-doctoral Fellowship. Project Title: “Galectin Function in Innate and Adaptive Immunity”. Principal Investigator: S. Jackson, Sponsor G.R. Vasta. Funding period: 36 months (2007-2009).

AWARDS TO GRADUATE AND UNDERGRADUATE STUDENTS UNDER MY SUPERVISION Kiran J. Harding “Assessment of in vitro growth of Perkinsus spp”, 1st prize Junior Science Competition (JSH) for the state of MD 2004; finalist at the Life Sciences at the JSH National competition, Baltimore 2004; Senior award Naval Science Award, ONR 2004; Statistical Thinking Award, Am. Soc. Qual. Baltimore, 2004; Second Prize, Baltimore Science Fair, 2004; Environmental Award, Baltimore Science Fair. Baltimore 2004; Grand Prize Baltimore Science Fair, Baltimore 2005. MEMBER OF STUDY SECTIONS AND REVIEW PANELS FOR FEDERAL AND STATE AGENCIES Review Section (Innate Immunity) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Tina McIntyre. 2004-2007 (Ad hoc) Review Section (Symbiosis, Defense and Self-recognition) from the National Science Foundation. Administrators: Dr. Michael Mishkind and Dr. Dona Boggs. 2007-present (Twice a year) Review Section (Tools for Zebrafish Research) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Neelakanta Ravindranath. 2006 (Ad hoc)

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Review Section (Vector Biology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. John C. Pugh. 2005-2006 (Ad hoc) Review Section (Signal Transduction and Regulation) from the National Science Foundation Administrator: Dr. Ronald Weiner 2001-2005 (Twice a year) Special Review Section (Immunobiology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Betty Hayden. 1994-present (Ad hoc, two-three times a year, Panel Chair on two meetings) Special Review Section, Fellowships (Immunobiology Fellowships) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. B. Hayden. Bethesda, Maryland: June, December 1998-present (Ad hoc, approx. once a year) Review Section from SC Sea Grant, NOAA. Administrator: Dr. Rick DeVoe; Charleston South Carolina, 1999-present (once every two years) Review Section (Immunology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Steve Nigida. 19992006 (Three times a year) Review Section (Tropical Medicine and Parasitology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Jean Hickman. 1996-2001. (Ad hoc) Review Section (Immunology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Nabeeh Mourad. Bethesda, Maryland, 1992-1999 (Three times a year) Special Review Section (Immunobiology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Gene Zimmerman. Bethesda, Maryland: December 1998. Grant Review Study Section. Sea Grant National Office, National Oceanic and Athmospheric Administration, United States Department of Commerce. Administrator: Dr. James Mc Vey. Silver Spring, Maryland, October 1997. Review Section Member, Fisheries and Marine Sciences Review panel, US Agency for International Development, Bureau of Global Programs, National Academy of Sciences. 1991, '92, '94. Committee for the Study of Research-Doctorate Programs in the United States, National Research Council, National Academy of Sciences. 1993. Review Panel, Ecological and Evolutionary Physiology, National Science Foundation. Administrator: Dr. Zoe Eppley 1999-2000. Grant Review Study Section. Sea Grant National Office, National Oceanic and Athmospheric Administration, United States Department of Commerce. Administrator: Dr. James Mc Vey. Silver Spring, Maryland, February 2005. Grant Review Study Section (Vector Biology) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. John Pugh. March 2005. Grant Review Study Section (Tools for Zebrafish Research) from the Division of Research Grants, Department of Health and Human Services, National Institutes of Health. Administrator: Dr. Neelakanta Ravindranath. March 2006.

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Review Section (Symbiosis, Defense and Self-recognition), Physiological and Structural Systems cluster from the National Science Foundation Administrator: Dr. Dona Bogs 2007 MEMBER OF ADVISORY PANELS FOR FEDERAL AGENCIES Shrimp Virus Peer Review Workshop. United States Environmental Protection Agency, National Center for Environmental Assessment. Arlington, Virginia, January 1998 Advisory Panel Member, Division of Cellular and Molecular Biosciences, National Science Foundation, Washington, DC (From March 1, 1994 to February 28, 1995) GRANT PROPOSALS REVIEWED FOR FEDERAL AND STATE FUNDING AGENCIES S-K Program, NOA, DOC; Northeastern Region Aquaculture Research Center United States Department of Agriculture, International Cooperation and Development Program; United States Department of Agriculture, Cooperative State Research, Educational and Extension Service; EPSCor Program, South Carolina/National Science Foundation; International Foundation for Science; Human Science Frontier International Development Program; Marine Fisheries Initiative (MARFIN) US Department of Commerce, NOAA, DOC; National Science Foundation, Cell Biology Program; Veterans Administration Medical Research Service; Sea Grant Colleges from Puerto Rico, Oregon and South Carolina, US Department of Commerce, NOAA, DOC; Cystic Fibrosis Foundation of Canada; Medical University of South Carolina, Institutional Research Funds, Office of Research and Sponsored Programs; Italian Ministry of Education, University and Research (MIUR/COFIN/CINECA; Italy); START Prize, Austrian Science Fund (FWF der Wissenschaftsfonds, Austria); South Carolina Research Centers of Economic Excellence, S.C. Commission on Higher Education. MEMBER OF EDITORIAL BOARDS ON SCIENTIFIC JOURNALS Journal of Experimental Zoology. Associate Editor, Division of Immunology and Parasitology 1993-1994. Developmental and Comparative Immunology. Editorial Board Member. 1993-1998. Fish Immunomodulator Newsletter. Committee Member. 1994-1995 DIRECTOR OF EDITORIAL BOARDS ON SCIENTIFIC JOURNALS Journal of Experimental Zoology. Director, Division of Immunology and Parasitology 1994-2000 REVIEW OF MANUSCRIPTS FOR SCIENTIFIC JOURNALS AND BOOKS

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Journal of Biological Chemistry, PNAS, Biochemistry, Journal of Experimental Biology, Biochimica et Biophysica Acta, BBRC, Archives of Biochemistry and Biophysics, Glycobiology, Glycoconjugate Journal, Comparative Biochemistry and Physiology, Journal of Parasitology, European Journal of Cell Biology, Gene, FEBS Journal, Developmental and Comparative Immunology, Marine Biotechnology, Journal of Invertebrate Pathology, Experimental Parasitology, Differentiation, Lipids, J. Eukaryotic Microbiology, European Journal of Biochemistry, Journal of Experimental Zoology, Fish and Shellfish Immunology and several other scientific journals. Marcel Dekker, Inc.(Book proposals and book manuscripts) and American Fisheries Society Publications (Book chapter manuscripts), etc. TEACHING EXPERIENCE “Mucosal Innate and Adaptive Immunity” International course organized in collaboration with Dr. A. Fossati, Supported by AMSUD-Pasteur and a J. William Fulbright Scholar International Award, US Department of State, Bureau of Educational and Cultural Affairs and the Council for International Exchange of Scholars (CIES), Facultad de Ciencias Exactas, UNLP, La Plata, Argentina, August-September 2007 “Evolution of Immune mechanisms” Lectures for the International course “Perspectives in Host Response to Infection” organized by Gunilla Karlsson Hedestam, Karolinska Institute, Stockholm, Sweden, October 2006 “The Sweet Tooth of Innate Immunity: Structural, Functional and Evolutionary Aspects of Humoral and Cell-Associated Lectins” Lecture for the course “Comparative Immunology” organized by F-L. Chu and S. Kaatari, Virginia Institute of Marine Science. February 2006 “Molecular approaches to parasitic disease in the eastern oyster Crassostrea virginica”. Lectures and laboratory work for 10-15 High School students from the Living Classrooms Foundation, Ingenuity Program, and Community College of Baltimore County (6-8 lectures per year) 2001-present “Disease in Aquaculture: Innate and adaptive immunity” Lecture for the VIRTUE Aquaculture Course “Finfish Aquaculture: Biological Basis and Current Developments” MEES 698G Seminar. Organized at COMB by John Trant, November 1999. “Biotechnology and diagnosis of disease in the eastern oyster Crassostrea virginica”. Lectures and laboratory work for 13 students (7th graders) from the Marine Sciences Program, Center for Academic Advancement, Living Classrooms Foundation, Johns Hopkins University Institute for the Academic Advancement of Youth. 1999-2000 "Biochemistry of Complex Carbohydrates" Chem. 682, Special Topics in Biochemistry. Chemistry Department. UMBC Spring Semester 1992; Fall Semester 1993; Spring Semester 1995; Spring Semester 1997. In collaboration with C. Allen Bush, Ph.D. “Molecular Approaches to the Study of Disease in Shellfish” Lecture for Sea Grant Extension Course in Marine Biotechnology. COMB. Course Director. Dr. Jonathan Kramer. Spring Semester 1997. "Biochemistry" Course Director: Dr. R. Poljak. Bowie State University, Bowie, Maryland. Fall Semesters 1995 and 1996.

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"Microbial Complex Carbohydrates: Biochemistry, Genetics and their Role in Microbe-Host interactions" International Course for Graduates and Faculty. Supported by UNESCO, UN. Institute of Biochemistry and Molecular Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. Three weeks during Fall 1995. Course CoOrganizer and Co-Director, with Professor N. Fink. "Physiology of Marine Invertebrates". Department of Biology, Johns Hopkins University. Spring Semester 1993. In collaboration with Harry Goldberg, Ph.D. "Complex Carbohydrates: Structure, Biosynthesis and Function" Course for Graduates and Faculty. Department of Biological Sciences, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. Three weeks during Fall Semester 1993. Course Organizer and Co-Director. In collaboration with C. Allen Bush, Ph.D. "Core Biochemistry", For Medical and Graduate students. Conference leader in "Biochemical Basis and Clinical Diagnosis of Disease" Department of Biochemistry, Medical University of South Carolina, Charleston, SC Fall Semesters 1983 - 1989. "Biochemistry of the Plasma Membrane". For graduate students. Department of Biochemistry, Medical University of South Carolina, Charleston, SC. Fall Semesters 1983 - 1989. "Immunochemistry". For Graduate Students, Department of Basic and Clinical Immunology and Microbiology, Medical University of South Carolina, Charleston, SC. Fall Semester 1983. "Immunology". For Graduate students, Department of Biochemistry, Medical University of South Carolina, Charleston, SC Fall Semester 1986 -1989. "Genetics and Immunology of Human Blood Groups." Course of Graduates. Organized by the Center of Specialists in Biological Analysis, Department of Biological Sciences, and the Society of Immunologists, La Plata, "Buenos Aires, 1973. "Human Anatomy". (9 months course) Department of Biological Sciences, National University, La Plata, Buenos Aires. 1973 -1979. "Pathological Anatomy and Physiology." (9 months course) Department of Biological Sciences, National University, La Plata, Buenos Aires. 1973 -1974. "General Biology" (9 months course) Department of Biological Sciences, National University, La Plata, Buenos Aires. 1970 -1972. GRADUATE PROGRAMS Faculty Member of the MEES Graduate Training Program, University of Maryland System, 1989 -present. Faculty Member of the Graduate Training Program from the Marine and Environmental Sciences, Universidad Nacional de Mexico, Mexico City and Merida, 2004-present Faculty Member of the MCBP Graduate Training Program, Marine Biomedicine & Environmental Sciences Center, Medical University of South Carolina, Charleston, 2003present. Chair of the Environmental/Biotechnology AOS, MEES Graduate Training Program Committee (Co-Chair: Dr. Paul Dunlap), University of Maryland System, 1995 -2001. UMBI Coordinator, MEES Graduate Training Program Committee, University of Maryland System, 1999 -2001.

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Member of the Committee for Internal and External Review of the MEES Graduate Training Program, University of Maryland System, 1996 -97 Faculty Member of the MCBP Graduate Training Program, Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 1985 -1989. POST-DOCTORAL TRAINING Past Maria T. Elola, Ph.D. (Research Career Member, National Council of Research, Argentina) Feng Hua Liu, Ph.D. (Research Staff Member, University of Beijing) Goutam Sen, Ph.D. (Assistant Professor, Uniformed Services University, Bethesda, MD) Anita Wright, Ph.D. (Assistant Professor, Univ. Florida at Gainsville) Adam G. Marsh, Ph.D. (Assistant Professor, Univ. Delaware) Lorena Vázquez, Ph. D. (Faculty Member, UNAM Mexico) Michael Quesenberry, Ph.D. (Staff Scientist Human Genome Sciences, Rockville, MD) Tomas Drgon, Ph.D. (Staff Scientist, National Institutes of Health, Bellview Hospital Baltimore, MD) Jana Drgonova, Ph.D. (Staff Scientist, National Institutes of Health, Bellview Hospital Baltimore, MD) Danara Krupatkina, Ph.D. (Research associate, COMB) Eric Odom-Crespo, Ph.D. (Research associate, National Institutes of Health, Bethesda, MD) Eric Schott, Ph.D. (Research Assistant Professor, COMB) Current Hafiz Ahmed, Ph.D. Jose A. Robledo, Ph.D. Keiko Saito, Ph.D. Satoshi Tasumi, Ph.D. Mohammad Alavi, Ph.D. Patricia Strickler-Dinglasan, Ph.D. Shawn Jackson, Ph.D. GRADUATE STUDENT TRAINING Scientific Advisor of Graduate Students Past Mr. Frederick J. Cassels (Medical University of South Carolina, Ph.D. 1986) Ms. Ann Snowden (Johns Hopkins University, M.Sc. 1994) Ms. Julie Gauthier (University of Maryland, MEES Program, Ph.D. 1997) Ms. Cathleen Coss (George Washington University, Ph.D. 2000) Ms. Nuala O'Leary (University of Maryland, MEES Program, Ph.D. 2003)

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Mr. Eric Odom-Crespo Mr. Davin Henrickson Ms. Natalia Mercer Mr. Wolfgang Pecher Current Ms. Zhouer Lin

(University of Maryland, MEES Program, Ph.D. 2004) (University of Maryland, MEES Program, Ph.D. 2004) (National University, La Plata, Argentina, Ph.D. 2006) (University of Maryland, MEES Program, Ph.D. 2007) (University of Maryland, MEES Program)

Scientific Advisor of Rotating Graduate Students Past Mr. Mark Saltis (University of Maryland School of Medicine, MCB Program; Lab. Rotation Spring-Summer 2005) Training of Students from Graduate Programs Abroad Past Mr. Geir O. Melingen (University of Bergen, Norway , 2000) Mr. Rodrigo Bibiloni (National University, La Plata, Argentina, 2001) Ms. Patricia Cabrita (University of Algarve, Portugal, 2001) Ms. Manuela Almeida (University of Algarve, Portugal, 2002) Ms. M. Theresa Posas Loreto (University of Los Baños, The Philippines, 2004-05) Ms. Rita Ascencio (University of Algarve, Portugal, 2004-2005) Ms. Natalia Mercer (National University, La Plata, Argentina, 2005) Ms. Laura Poisa Beiro (University of Vigo, Spain, 2006) Current Ms. Elisabetta Caccia (University of Tuscia, Viterbo, Italy, 2006-07)

Member of Graduate Student Committees Past Ms. Zuquin Nie (M. Wu, Committee Chair. MCB Program, 1990) Mr. Kenneth Wiencek (M. Fletcher, Committee Chair. MEES Program, 1991) Mr. Mike Shamblott (T. Chen, Committee Chair. MCB Program, 1993) Ms. Ruth Kelty (K. Sebens/C. D’Elia, Committee Chair. MEES Prog.1994) Ms. Cassandra Moe (A. Place, Committee Chair. MEES Program, 2001) Mr. Eric Lund (A. Place, Committee Chair. MEES Program, 2002) Mr. Matthew Jenny (R. Chapman, Committee Chair. Med. Univ. of SC 2005) Ms. Tonya Koropatnik (M. McFall-Ngai, Committee Chair. Univ. of Hawaii 2005) Current Ms. Debbie Howard Ms. Mercedes Roca Mr. Soumya Ganguli Mr. Juan Alpuche Osorno (F. Robb, Committee Chair. MEES Program) (F. Asencio, Committee Chair. Univ. of La Paz, Mexico) (A. Bush, Committee Chair. MEES Program) (E. Zenteno, Committee Chair. Univ. Natl. de Mexico)

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UNDERGRADUATE STUDENT TRAINING Scientific Advisor of the Undergraduate Students Past Ms. Hong Tran (CCB, MD) 1990 Mrs. Geraldine Kennedy (NCCB, MD) 1992 Ms. Sherry Davies (NCCB, MD) 1993 Ms. Tina Libby (NASA, Sharp Plus, 1996) Ms. Cristina Salvador (NASA, Sharp Plus, 1996) Mr. Steven Gibson (NSF REU, 1996) Ms. Tanya Monton (NASA, Sharp Plus, 1997) Ms. Veronica Malavé (NASA, Sharp Plus, 1997) Ms. Lauren Boudra (UMBC, MD, 1997) Mr. John Pisciotta (Eckerd College, FL, 1997) Ms. Brandy Doutherd (NASA, Sharp Plus, 1998) Ms. Katie Venanzy University of MD, College Park, 1998) Ms. Dewey Richmond, III (NASA, Sharp Plus, 1998) Ms. Shermain Sultana (Baltimore Community College, 1999) Mr. Federico Argemi (University of La Plata, 1999/2000) Mr. Gary Conyers (NIH Undergraduate Fellow, 2000) Mr. Orlando Yarborough (UMBC, NIH Undergraduate Fellow, 2000) Ms Harmony Hancock (University of Pennsylvania, PA 2002) Ms Teaike Butts (LMRCSC Program, COMB-Coppin College, 2005) Mr. David Hall (LMRCSC Program, COMB-Coppin College, 2006) Scientific Advisor of the High School Interns Past Mr. Bill Stoyer (Centennial High School, 1998/99) Mr. Orlando Yarborough (The Park School, 1999) Mr. Andrey Zuk (Ingenuity Program, Baltimore MD, 2000) Mr. Azaria Tesfa (The Park School, 2000) Mr. Mike Warren (Biotechnology Program, Howard County MD, 2001) Ms. Laura Roth (Biotechnology Program, Howard County MD, 2002-03) Mr. Sean Berg (Ingenuity Program, Baltimore MD, 2002-03) Mr. Vincent Barracchini (Biotechnology Program, Howard County MD, 2003) Mr. Kiran J. Harding (Biotechnology Program, Howard County MD, 2003-05) Ms. Jerusa Contee (Biotechnology Program, Howard County MD, 2004-05) Ms. Alison Burris (The Park School, 2005) Ms. Tiffany Yeh (Thomas Jefferson High School for Sci.&Technol, 2006) Ms. Sharon Kim (Thomas Jefferson High School for Sci.&Technol, 2006) Current Mr. Jeewon Kim Ms. Claudia Solis-Roman (Thomas Jefferson High School for Sci.&Technol, 2007) (Thomas Jefferson High School for Sci.&Technol, 2007)

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Scientific Advisor of the High School Science Teacher Interns Past Ms. Beverly Feig (Martin Marietta Fellow, 1995) Mr. Steven Shiflett (ExPert Program, NSF, 2004) Ms. Nicole Holmes (ExPert Program, NSF, 2005) Mr. Gwendolin Müllen (Environmental Science Education Partnership Chesapeake Teacher Fellowship 2005-2006) Ms. Claire LeFebvre (ExPert Program, NSF, 2006) Ms. Lisa Voketitis (ExPert Program, NSF, 2006) DOCTORAL THESIS AND PROMOTION (EXTERNAL REFEREE) Mr. Goutam Sen, Jadavpur University, Calcutta, India (Prof. Chitra Mandal, Chair and Scientific Advisor) 1993. Mr. Rathod Vijayakumar Premsing, Karnatak University, Dharwad, India (Prof. A. H. Parulekar, Chair and Scientific Advisor) 1993. Ms. Jenny Rodriguez, University of Montpellier, Montpellier, France (Prof. Evelyne Bachere, Scientific Advisor) 1994. Virginia Institute of Marine Science, External Referee for Promotion and Tenure, 1995 Florida International University, External Referee for Promotion & Tenure, 1996 Mr. Leigh M. Schmidtke, University of Tasmania, Tasmania, Australia (Prof. Barry Munday, Scientific Advisor) 1996 Florida International University, External Referee for Promotion & Tenure, 2003 Mr. Peter Green, University of Mebourne, Australia (Prof. David Raftos, Scientific Advisor) 2006 VISITING FACULTY IN MY LABORATORY Dr. N. E. Fink, Professor of Biological Sciences Research project: "Developmentally Regulated Lectins from Vertebrates"1990, '92, '95; Dr. H. Yu, Senior Scientist. Veridian Corp./US Air Force Armstrong Laboratory Research project: " Development of a microplate chemifluorimmunoassay for rapid detection of bacteria and toxin in blood " 1997 Dr. Florence Okafor, Lagos University, Nigeria. Research project: "Dose-response to Vibrio species” Section:“ Methods for experimental infection and assessment of Vibrio cholerae in Crassostrea virginica") 1999-2003 Dr. A. Cortizo. University of La Plata, Argentina, Research Project “Regulation of galectin in osteoblast differentiation and malignancy” 2001-2002 Dr. M. Cammarata, University of Palermo, Italy, Research Project “Gene organization of an F-lectin from the sea bass Dicentrarchus labrax” 2003 Dr. V. Connors, University of South Carolina, Spartanburg, Sabbatical Research Project “Molecular approaches to the study of P. marinus and its host, C. virginica” 20032004

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Dr. M. Cammarata, University of Palermo, Italy, Research Project “Biological role of an F-lectin from the sea bass Dicentrarchus labrax” December 2006 Dr. N. Romano, University of Tuscia, Viterbo, Italy, Research Project “Expression of antimicrobial peptides in zebrafish Danio rerio” December 2006-March 2007 INSTITUTIONAL SERVICE Committee Duties Center of Marine Biotechnology Faculty Appointments Committee (1991-Present) Aquaculture Research Facilities Committee (1993-Present) Animal Care and Use Committee (1994-2005) Biosafety Committee (1998-2005) COMB Research Equipment Committees (1995) Faculty Search Committee (Aquaculture/Biotech, 1995) Faculty Search Committee (Chair, Microbiol./Biotech., 1995/96) Faculty Search Committee (Gene Transfer/ Aquaculture, 1996/97) Faculty Search Committee (Eukaryotic Molecular Biology, 1992) Faculty Search Committee (Chair, Fish Immunology, 2000) Promotion and Tenure Review Committee (Chair, 2001) Faculty Search Committee (Crustacean Physiology, 2002) Faculty Search Committee (Chair, Fish Immunology, 2004-2005) University of Maryland Biotechnology Institute Promotion and Tenure Review Committee (1993) COMB Director Search Committee (1994) UMBI Core Facilities Committee (1994) UMBI Annual Symposium Committee (1993/1994) UMS/UMBI Student Information System Task Force (1996/97) CAB Search Committee (1998/99) CARB Promotions and Tenure Committee (1998/99) Promotion and Tenure Review Committee [2003, 2005, 2006, 2007 (chair)] State of Maryland Maryland Harmful Algal Technical Advisory Committee (1999-2004) Federal Agencies, USA External Advisory Committee Member, Undergraduate Student Training in Academic Research Program (MARC U-STAR Program) funded by NIH. FIU, Miami, Florida (2000-2005; 2006-2008) External Advisory Committee Member, NOAA Center of Excellence in Oceans and Human Health. Marine Biomedicine and Environmental Sciences Center

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Medical University of South Carolina, Hollings Marine Laboratory, Charleston, South Carolina (2005-2008) External Advisory Committee Member, Research Initiative for Scientific Enhancement Program (MBRS RISE Program) funded by NIH. FIU, Miami, Florida (2000-2005; 2006-2008) External Advisory Committee Member, ARCH program, NIEHS. PI: Kelly Rein, Ph.D., FIU, Miami,Florida (2001-2006) Technical Advisory Committee Member for the Oregon/Hawaii Sea Grant Program: Marine Biotechnology Education and Outreach program, Hawaii (2004-present). Senate, University of Maryland Biotechnology Institute UMBI Senator for COMB (1997-2002) Supervision of Center Research Facilities Head of the Hybridoma and Immunochemistry Facility, Center of Marine Biotechnology (1989-present) Head of the Core Facility for Culture of Toxic Dinoflagellates (Biosafety level 2 and level 3 facilities), Center of Marine Biotechnology (1998-2004) ORGANIZATION AND CHAIR OF MEETINGS, SYMPOSIA AND WORKSHOPS Co-Organizer and Chair of the workshop "The Forgotten Creatures: Immunity in Invertebrates" 3rd Congress of the International Society of Developmental and Comparative Immunology. Reims, France. July 1985. Chair of the General Biology Section, 1st International Workshop on Crustacean Biology. Universita Degli Studi di Trieste, Trieste, Italy. September 1985. Organizer and Chair of the Workshop "Recognition Mechanisms in Deuterostomate Invertebrates" Fifth International Congress of Developmental and Comparative Immunology, Portland, Oregon, August 4-9, 1991. Co-Organizer and Chair of the Symposium "Invertebrate Cellular Immunity: In Vitro Aspects" World Congress of Cell and Tissue Culture, Washington, DC. 20-25 June 1992. Chair of the Session "Invertebrate Immunity". International Society of Invertebrate Pathology. Heidelberg, Germany. August 1992. Co-Organizer of the First Annual Symposium of the Maryland Institute of Biotechnology. Organizer and Chair of the Session: "Molecular Recognition and Signal Transduction". January 1993 Co-Chair of the Symposium: "Immune Recognition: Evolutionary Aspects". Annual Meeting of the American Association of Immunologists. Denver, Colorado, May 1993. Chair of the Session "Molecular Recognition of Non-Self" Comparative Immunology Annual Meeting, Breckenridge, Colorado, July 1995. Chair of the Round Table: "Complex Carbohydrates from Microorganisms", Institute of Biochemistry and Molecular Biology, School of Exact Sciences, National University, La Plata, Buenos Aires, Argentina. August 1995.

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Member of the Organizing Committee for the 7th World Congress of the International Society for Developmental and Comparative Immunology, Williamsburg, Virginia, USA, July 1997. Chair and Organizer of the Session: “Immunobiology of Lectins”. 7th World Congress of the International Society for Developmental and Comparative Immunology, Williamsburg, Virginia, USA, July 1997. Member of the Organizing Committee for the Workshop: “Development and Application of Molecular Technologies to Pfiesteria Research. A Research Workshop”. Center of Marine Biotechnology, UMBI, Baltimore Maryland, October 1997. Member of the Organizing Committee for the World Congress of Malacology, Washington DC, USA, July 1998. Member of the Local Committee for the 3rd International Symposium on Aquatic Animal Health, Baltimore, MD, USA, August-September 1998. Co-organizer of the Annual Meeting of the Mid-Atlantic Society for Comparative Immunology. George Washington University, Washington DC. C. Smith, Organizer. August 1999 Organizer of the workshop "Molecular Approaches for Identification and Environmental Detection of Pfiesteria piscicida and Pfiesteria-like Dinoflagellates" Center of Marine Biotechnology, UMBI, Baltimore, Maryland. Co-organized with W. Litaker and C. Scholin, sponsored by ECOHAB. September 1-2, 1999. Co-organizer of Session II “Pathogens/Health Assessments” from the “Workshop on the Interactions Among the Environment, the Endocrine and Immune Systems and Resistance to Disease in Marine Organisms”. Co-organized with S. Kaattari and J-A Leong. Honolulu, Hawaii. June 25-29, 2000 Member of the Organizing Committee for the Symposium: “Innate Immunity: Molecular and Evolutionary Aspects” Aegean Conferences. Co-organized with J. Lambris, J. Volanakis and I. Zarkadis. Conference Center, Santorini, Greece. October 10-14, 2000 Co-Chair of the Symposium: "NK Cell and Receptors in Innate Immunity". ISDCI/AAI at the FASEB Annual Meeting. New Orleans, Louisiana, April 2002. Chair and organizer of Session “Structural Biology” from the “EUROCARB” Grenoble, France. July 2003 Chair and organizer of Session “Lectins, TLRs, and PAMPs”, 10th Congress of the International Society of Comparative and Developmental Immunology Charleston, South Carolina, July, 2006 Chair and organizer of Session “Marine Organismal Molecular Biology and Biotechnology”, 8th International Marine Biotechnology Conference, Eilat, Israel, March 10-16, 2007 PARTICIPATION/COORDINATION OF INTERNATIONAL COOPERATION AGREEMENTS AND RESEARCH PROGRAMS French-USA Program on Transgenic Invertebrates and Shrimp Aquaculture, Embassy of France, Washington, DC, USA. Dec. 1992-present. International Memorandum of Understanding between the National University, La Plata, Buenos Aires, Argentina and Maryland Institute of Biotechnology, Maryland, USA, 1991-present.

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Indo-USA Cooperation Program: Coordinated scientific interactions between COMB and the National Institute of Oceanography, Goa, India. 1991 Memorandum of Understanding between UMBI, UMD and Universtity of Tuscia, Viterbo. 2006 MEMBERSHIP TO SCIENTIFIC SOCIETIES International Society of Aquatic Genomics (Founding member); American Society of Biological Chemistry and Molecular Biology; International Society for Developmental and Comparative Immunology; National Shellfisheries Society; NIH Glycoconjugate Interest Group; American Association for Advancement of Science. OTHER PROFESSIONAL ACTIVITIES AIBS-ONR Consultant to the Indo-United States Collaboration Program. Attended the Indo-USA Subcommission on Science and Technology Meeting in Delhi, November 1991. International Society of Developmental and Comparative Immunology, Member of the Nominating Committee 1994-95 PUBLICATIONS (ABSTRACTS ARE NOT INCLUDED) Refereed Publications Vasta, G. R., Chiesa, M.E. and Palatnik, M. Agglutinins and protectins in the snail Borus. Medicina 36: 107-112, 1976. Vasta, G.R., Ilodi, G.H.U., Cohen, E. and Brahmi, Z. A comparative study on the specificities of Androctonus australis (Saharan scorpion) and Limulus polyphemus (Horseshoe crab) agglutinins. Develop. Comp. Immunol. 6: 625-634, 1982. Vasta, G.R. and Cohen, E. The specificity of Centruroides sculpturatus Ewing (Arizona lethal scorpion) agglutinins. Develop. Comp. Immunol. 6: 219-230, 1982. Vasta, G.R., Warr, G.W. and Marchalonis, J.J. Tunicate lectins: Distribution and specificity. Comp. Biochem. Physiol. 73: 887-900, 1982. Vasta, G.R., Sullivan, J.T., Cheng, T.C., Marchalonis, J.J. and Warr, G.W. A cell membraneassociated lectins of the oyster hemocyte. J. Invert. Pathol. 40: 367-377, 1982. Vasta, G.R., Warr, G.W. and Marchalonis, J.J. Serological characterization of humoral lectins from the freshwater prawn Macrobrachium rosenbergii. Develop. Comp. Immunol. 7: 13-20, 1983. Vasta, G.R. and Marchalonis, J.J. Humoral recognition factors in the Arthropoda. The specificity of Chelicerata serum lectins. Am. Zool. 23: 157-171, 1983. Vasta, G.R. and Cohen, E. Naturally occurring hemagglutinins in the hemolymph of the scorpion Paruroctonus mesaensis Stahnke. Experientia 39: 721-722, 1983.

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Warr, G.W., Ledford, B.E., Vasta, G.R. and Marchalonis, J.J. Evidence for the existence of a diverse family of immunoglobulin-related recognition molecules. J. Immunogenet. 10: 17-23 (1983). Hunt, J.C., Vasta, G.R. and Marchalonis, J.J. Antigenic and structural characteristics of an immunoglobulin-related peptide purified from marmoset T-lymphocyte cells. Cell Immunol. 75: 22-42, 1983. Marchalonis, J.J., Vasta, G.R,. Hunt, J.C., Wang, A.C. and Minowada, J. Some T-cell leukemia lines express surface markers related to a restricted set of human VH determinants. Cell. Immunol. 77: 161-175, 1983. Warr, G.W., Vasta, G.R,. Marchalonis, J.J., Allen, R.C. and Anderson, D.C. Molecular analysis of the lymphocyte membrane. Dev. Comp. Immunol. 8: 757-772, 1984. Vasta, G.R. and Cohen, E. Sialic acid binding lectins in the "whip scorpion" Mastigoproctus giganteus serum. J. Invert. Pathol. 43: 333-342, 1984. Vasta, G.R. and Cohen, E. Carbohydrate specificities of Birgus latro (Coconut crab) serum lectins. Develop. Comp. Immunol. 8: 197-202, 1984. Vasta, G.R. and Cohen, E. Humoral lectins in the scorpion Vaejovis confuscius. A serological characterization. J. Invert. Pathol. 43: 226-233, 1984. Vasta, G.R. and Cohen, E. Serum lectins from the scorpion Vaejovis spinigerus bind sialic acids. Experientia 40: 485-487, 1984. Marchalonis, J.J., Vasta, G.R., Warr, G.W. and Barker, W.C. Probing the boundaries of the extended immunoglobulin family of recognition molecules: Jumping domains, convergence and minigenes. Immunol. Today 5: 133-142, 1984. Vasta, G.R. and Cohen, E. Sialic acid binding lectins in the serum of American spiders of the genus Aphonopelma. Develop. Comp. Immunol. 8: 515-522, 1984. Vasta, G.R. and Cohen, E. Characterization of the carbohydrate specificity of serum lectins from the scorpion Hadrurus arizonensis Stahnke. Comp. Biochem. Physiol. 77B: 721-727, 1984. Vasta, G.R., Cheng, T.C. and Marchalonis, J.J. A lectin on the hemocyte membrane of the oyster (Crassostrea virginica). Cell. Immunol. 88: 475-488, 1984. Vasta, G.R., Warr, G.W. and Marchalonis, J.J. Receptors for non-self in the animal kingdom. Dev. Comp. Immunol. 3: 139-146, 1984. Vasta, G.R., Marchalonis, J.J. and Kohler, H. An invertebrate recognition protein cross-reacts with an immunoglobulin idiotype. J. Exp. Med. 159: 1270-1276, 1984. Mackel-Vandersteenhoven, A., Vasta, G.R., Waxdal, M.J. and Marchalonis, J.J. Segmental homology between T-cell receptors and immunoglobulin variable regions: evidence that antisera to synthetic JH1 peptide react with murine and human T-cell products. Proc. Soc. Exp. Biol. Med. 178: 475-485, 1985. Vasta, G.R. and Marchalonis, J.J. Humoral and cell membrane-associated lectins from invertebrates and lower chordates: Specificity, molecular characterization and their structural relationships with putative recognition molecules from vertebrates. Dev. Comp. Immunol. 9: 531-539, 1985. Rosenshein, I.L., Schluter, S.F., Vasta, G.R. and Marchalonis, J.J. Phylogenetic conservation of heavy chain determinants of vertebrates and protochordates. Dev. Comp. Immunol. 9: 783-795, 1985.

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Cassels, F.J., Marchalonis, J.J. and Vasta, G.R. Heterogeneous humoral and hemocyte-associated lectins with N-acylamino sugar specificities from the blue crab Callinectes sapidus Rathbun. Comp. Biochem. Physiol. 85B: 23-30, 1986. Vasta, G.R., Hunt, J., Marchalonis, J.J. and Fish, W.W. Galactosyl-binding lectins from the tunicate Didemnum candidum. Purification and physicochemical characterization. J. Biol. Chem. 261: 9174-9181, 1986. Vasta, G.R., Marchalonis, J.J. and Decker, J. Binding and mitogenic properties of a galactosylspecific lectin from the tunicate Didemnum candidum for murine thymocytes and splenocytes. J. Immunol. 137: 3216-3223, 1986. Vasta, G.R. and Marchalonis, J.J. Galactosyl-binding lectins from the tunicate Didemnum candidum. Carbohydrate specificity and characterization of the combining site. J. Biol. Chem. 261: 9182-9186, 1986. Vasta, G.R. and Marchalonis, J.J. Lectins from protochordates as putative recognition molecules. Proc. Clin. Biol. Res. 233: 23-32, 1987. Lackie, A.M. and Vasta, G.R. The role of a galactosyl-binding lectin in the cellular immune response of the cockroach Periplaneta americana (Dictyoptera). Immunology 64: 353357, 1988. Beck, G., Vasta, G.R., Marchalonis, J.J. and Habicht, G.S. Characterization of interleukin-1 activity in tunicates. Comp. Biochem. Physiol. 92B: 93-98, 1989. Gauthier, J.D. and Vasta, G.R. Continuous in vitro culture of the eastern oyster parasite Perkinsus marinus. J. Invert. Pathol. 62:321-323, 1993. Liao, D-I, Kapadia, G., Ahmed, H., Vasta, G.R. and Herzberg, O. Structure of S-lectin, a developmentally regulated vertebrate -galactoside-binding protein. Proc. Natl. Acad Sci. 91: 1428-1432, 1994. Gauthier, J.D. and Vasta, G.R. Inhibition of the in vitro replication of the oyster parasite Perkinsus marinus by the natural iron chelators transferrin, lactoferrin and desferrioxamine. Develop. Comp. Immunol. 18: 277-286, 1994. Ahmed, H. and Vasta, G. R. Galectins: conservation of functionally and structurally relevant amino acid residues defines two types of carbohydrate recognition domains. Glycobiology. 4: 545-549, 1994. Gauthier, J. D., Feig, B. and Vasta, G. R. Effect of fetal bovine serum glycoproteins on the in vitro proliferation of the oyster parasite Perkinsus marinus: Development of a fully defined medium. J. Euk. Microbiol. 42: 307-313, 1995. Gauthier, J.D. and Vasta G.R. In Vitro culture of the eastern oyster parasite Perkinsus marinus: Optimization of the methodology. J. Invert. Pathol. 66:156-168, 1995. Marsh, A.G., J.D. Gauthier and G.R. Vasta. A semiquantitative PCR assay for the detection and enumeration of Perkinsus marinus infections in the eastern oyster, Crassostrea virginica. J. Parasitol. 81:577-583, 1995. Vasta, G.R., Gauthier, J.D. and Marsh, A.G. Molecular and biochemical adaptations of the protozoan pathogen Perkinsus marinus for its host, Crassostrea virginica: Current research and future perspectives [or “The Best Defense is a Good Offense”]. J. Mar. Biotech. 3: 35-41, 1995 Ahmed, H., Fink, N. E., Pohl, J. and Vasta, G. R. Galectin-1 from bovine spleen: Biochemical characterization, carbohydrate specificity and tissue-specific isoform profiles J. Biochem. 120:1007-1019, 1996.

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Ahmed, H., Pohl, J., Fink, N. E., Strobel, F and Vasta, G. R. The primary structure and carbohydrate specificity of a -galactosyl-binding lectin from toad (Bufo arenarum Hensel) ovary reveal closer similarities to the mammalian galectin-1 than to the galectin from the clawed frog Xenopus laevis. J. Biol. Chem. 271:33083-33094, 1996. Vasta, G. R., Ahmed, H., Amzel, L. M. and Bianchet, M A. Galectins from amphibian species: Carbohydrate specificity, molecular structure, and evolution. Trends Glycosci. Glycotech. 9: 131-144, 1997. Magor, K.E. and G.R. Vasta. (1998) Ancestral immunity comes of age. Immunol. Today. 19: 5456, Yu, H., Ahmed, H. and G.R. Vasta. (1998). Development of a magnetic microplate chemifluorimmunoassay for rapid detection of bacteria and toxin in blood. Anal. Biochem. 261: 1-7. Schwarz, F. P., Ahmed, H. and G.R. Vasta. (1998) The thermal stability and thermodynamics of disaccharide binding to bovine spleen galectin-1. Biochemistry. 37: 5867-5877 Robledo, J.A.F., Gauthier, J.D., Coss, C.A., Wright, A.C., and Vasta G.R. (1998) Speciesspecificity and sensitivity of a PCR-based assay for Perkinsus marinus in the eastern oyster, Crassostrea virginica. a comparison with the fluid thioglycolate assay. J. Parasitol. 84:1237-1244 Robledo, J.A., Wright, A.C., Marsh, A.G. and Vasta G.R. (1999) Nucleotide sequence variability in the non-transcribed spacer of the rRNA locus in the oyster parasite Perkinsus marinus J. Parasitol. 85: 650-656 Vasta, G.R., Quesenberry, M., Ahmed, H., and O’Leary, N. (1999) C-type lectins and galectins mediate innate and adaptive immune functions: Their roles in the complement activation pathway. Develop. Comp. Immunol. 23:401-420 Harvell, C.D., Kim, K., Burkholder, J.M., Colwell, R.R., Epstein, P.R., Grimes, D.J., Hofmann, E.E., Lipp, E.K., Osterhaus, A.D.M.E., Overstreet, R.M., Porter, J.W., Smith, G.W., and Vasta, G.R. (1999) Emerging marine diseases-climate links and anthropogenic factors. Science, 285: 1505-1510 Bianchet, M.A., Ahmed, H., Vasta, G.R., Amzel, L.M. (2000) A soluble ß-galactosyl-binding lectin (galectin) from toad (Bufo arenarum Hensel) ovary: Crystallographic studies of two protein-sugar complexes. Proteins, 40: 378-388, Robledo, J.A.F., Pecher, W. T., Vasta, G.R. (2000) High-throughput isolation of oyster DNA facilitates diagnosis of "Dermo" disease. QIAGEN News. 5: 15-17. Robledo, J.A., Coss, C. A., and Vasta G.R. (2000) Characterization of the ribosomal RNA locus of Perkinsus atlanticus, and development of a polymerase chain reaction–based diagnostic assay. J. Parasitol. 86:972-978 Bianchet, M.A., Ahmed, H., Vasta, G.R., Amzel, L.M. (2000) A soluble ß-galactosyl-binding lectin (galectin) from toad (Bufo arenarum Hensel) ovary: Crystallographic studies of two protein-sugar complexes. Proteins, 40: 378-388 El-Nabawi, A., M. S. Quesenberry, K. Saito, E. Silbergeld, G. R. Vasta, and A. Eldefrawi (2000) The N-methyl-D-aspartate neurotransmitter receptor is a mammalian brain target for the dinoflagellate Pfiesteria piscicida toxin. Toxicol. Appl. Pharmacol. 169: 84-93 Vasta, G.R., Quesenberry MS, Ahmed H, O'Leary N. (2001) Lectins from tunicates: structurefunction relationships in innate immunity. Adv Exp Med Biol. 484:275-287.

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Coss CA, Robledo JA, Ruiz GM, Vasta GR. (2001) Description of Perkinsus andrewsi n. sp. isolated from the Baltic clam (Macoma balthica) by characterization of the ribosomal RNA locus, and development of a species-specific PCR-based diagnostic assay. J Eukaryot Microbiol. 48: 52-61. Coss CA, Robledo JA, Vasta GR. (2001) Fine structure of clonally propagated in vitro life stages of a Perkinsus sp. isolated from the Baltic clam Macoma balthica. J Eukaryot Microbiol. 48: 38-51. Steidinger, K., Landsberg J, Richardson RW, Truby E, Blakesley B, Scott P, Tester P, Tengs T, Mason P, Morton S, Seaborn D, Litaker W, Reece K, Oldach D, Haas L, Vasta G. R. (2001) Classification and identification of Pfiesteria and Pfiesteria-like species. Environ Health Perspect. 109 (Suppl 5): 661-665. Robledo, J. A. F., Saito, K., Steidinger, K., Vasta, G. R. (2002). The non-transcribed spacer of the rRNA locus as a target for specific detection of the dinoflagellate Pfiesteria piscicida and parasites (Perkinsus spp.). In: G.M. Hallegraeff, S.I. Blackburn, C.J. Bolch, R.J. Lewis (eds), Ninth International Conference on Harmful Algal Blooms, Intergovernmental Oceanographic Commission of UNESCO, Hobart, Australia, 7-11 February, 2000, pp. 238-241. Vasta G.R., Lambris J.D. (2002) Innate immunity in the Aegean: ancient pathways for today's survival. Dev. Comp. Immunol. 26: 217-225. Robledo, J.A.F., Nunes, P.A., Cancela, M.L. and G.R. Vasta (2002) Development of an in vitro clonal culture and characterization of the rRNA gene cluster of Perkinsus atlanticus, a protistan parasite of the clam Tapes decussatus. J. Euk. Microbiol 49: 414–422 Ahmed, H., M.A. Bianchet, L.M. Amzel, J. Hirabayashi, K.-i. Kasai, Y.Giga-Hama, H. Tohda, and G.R. Vasta (2002) Novel carbohydrate specificity of the 16 kDa galectin from Caenorhabditis elegans: binding to blood group precursor oligosaccharides (Type 1, Type 2, T and Tß) and gangliosides. Glycobiology 12:451-461 , Quesenberry, M.S., K. Saito, D.N. Krupatkina, J.A.F. Robledo, T. Drgon, W.T. Pecher, N. O'Leary, M. Alavi, T. Miller, R.E. Schneider, R. Belas, J.R. Deeds, A.R. Place, Y. Zohar, and G.R. Vasta (2002) Bioassay for ichthyocidal activity of Pfiesteria piscicida: Characterization of a culture flask assay format. J. Appl. Phycol. 14: 241-254 Bianchet, M. A., E. W. Odom, G. R. Vasta and L. M. Amzel (2002) A novel fucose recognition fold involved in innate immunity. Nature (Struct. Biol.) 9:628-634 Wright, A. C., H. Ahmed, J. D. Gauthier, A. M. Silva, and G. R. Vasta (2002) cDNA cloning and characterization of two iron superoxide dismutases from the oyster parasite Perkinsus marinus. Mol. Biochem. Parasitol. 123:73-77 Saito, K., Drgon, T., Robledo, J.A.F., Krupatkina, D.N. Vasta, G.R. (2002) Characterization of the rRNA locus of Pfiesteria piscicida, and development of standard and quantitative PCR-based detection assays targeted to the non-transcribed spacer. Appl. Environ. Microbiol. 68:5394-407. Gauthier, J.D. and G.R.Vasta. (2002). Effects of plasma from bivalve mollusk species on the in vitro proliferation of the protistan parasite Perkinsus marinus. J. Exp. Zool. 292:221-230 Schott, E.J., Vasta, G.R. (2003) The PmSOD1 gene of the protistan parasite Perkinsus marinus complements the sod2Delta mutant of Saccharomyces cerevisiae, and directs an iron superoxide dismutase to mitochondria. Mol Biochem Parasitol. 126(1): 81-92.

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Schott, E.J., J.A.F. Robledo, A. C. Wright, A. M. Silva, and G. R. Vasta. (2003) Gene organization and homology modeling of two iron superoxide dismutases of the early branching protist Perkinsus marinus. Gene 24:309:1-9. Ahmed, H., E. J. Schott, J. D. Gauthier, and G. R. Vasta (2003) Superoxide dismutases from the oyster parasite Perkinsus marinus: purification, biochemical characterization, and development of a plate microassay for activity. Anal. Biochem 318(1): 132-141 Quesenberry, M.S., H. Ahmed, M. T. Elola, N. O’Leary and G. R. Vasta. (2003) Diverse lectin repertoires in tunicates mediate broad recognition and effector innate immune responses. Integr. Comp. Biol. 43 (2): 323–330 Schott, E.J., W.T. Pecher, F. Okafor, and G. R. Vasta. (2003) The protistan parasite Perkinsus marinus is resistant to selected reactive oxygen species. Exp Parasitol.105 (3-4):232-40. Ahmed, H., S.-J. Du, N. O’Leary, and G.R. Vasta. (2004) Biochemical and molecular characterization of galectins from zebrafish (Danio rerio). Notochord-specific expression of a proto type galectin during early embryogenesis. Glycobiology 14(3):219-32 Vasta, G.R, Eric W. Odom, EO, Ahmed, H., Henrikson, D. and Saito, K. (2004) Lectins as recognition and effector factors in innate immunity of teleost fish. Mar. Biotech. 6: S128S134 Elandalloussi, L.M., Leite, R.M, Afonso, R., Nunes, P.A., Robledo, J.A.F., Vasta, G.R., and Cancela, M.L. (2004) Development of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs. Mol Cell Probes. 18(2):89-96. Pecher, W.T., J. A. F. Robledo, and G. R. Vasta (2004) Identification of a second rRNA gene unit in the Perkinsus andrewsi genome. J Eukaryot Microbiol. 51(2):234-45. Mercer, N. G.R. Vasta, H. Ahmed, A. McCarthy, S.B. Etcheverry, A. Cortizo (2004) AGER3/galectin-3 expression in osteoblast-like cells: regulation by AGEs. Mol Cell Biochem. 266(1-2):17-24. Vasta, G.R., Ahmed, H., Du, S-J. and Henrikson, D. (2004) Galectins in teleost fish: Zebrafish (Danio rerio) as a model species to address their biological roles in development and innate immunity. Glycoconj J. 21(8-9):503-21. Robledo, J.A.F., P. Courville, M.F. M. Cellier, and G.R. Vasta (2004) Gene organization and expression of the divalent cation transporter Nramp in the protistan parasite Perkinsus marinus. J Parasitol. 90(5):1004-14. Vasta, G.R, Ahmed, H. and Odom, E.O., (2004) Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates. Curr Opin Struct Biol. 14(5):617-30. Drgon, T., K. Saito, D.N. Krupatkina, P. Gillevet, B. Whitaker, and G.R. Vasta (2005) Characterization of ichthyocidal activity of Pfiesteria piscicida: dependence on the dinospore cell density. Appl Environ Microbiol. 71(1):519-29. Odom, E.W. and G.R. Vasta. (2006) Characterization of a binary tandem domain F-type lectin from striped bass (Morone saxatilis). J Biol Chem. 281(3):1698-1713 Asojo, O.A., Schott, E.J., Vasta, G.R., and Silva, A.M. (2006) Structures of PmSOD1 and PmSOD2, two superoxide dismutases from the protozoan parasite Perkinsus marinus Acta Crystallograph. 62:1072-1075

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Cammarata, M., Benenati, G., Odom, E.W., Salerno, G., Vizzini, A., Vasta, G.R. and Parrinello, N. (2007) Isolation and characterization of an F-type lectin from gilt head bream (Sparus aurata) serum. Biochim. Biophys. Acta. 1770:150-155 Ahmed, H., Banerjee, P.P. and Vasta, G.R. (2007) Differential expression of galectins in normal, benign and malignant prostate epithelial cells: Silencing of galectin-3 expression in prostate cancer by its promoter methylation. Biochem Biophys Res Commun.

358:241-6
Elola, M.T., Wolfenstein-Todel, C., Vasta G.R. and Rabinovich, G.A. (2007) Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival. Cell

Mol Life Sci. 64:1679-700.
Vasta, G.R., Ahmed, H., Saito, K., Odom, E.W., and Tasumi, S. (2007) Biological Roles of Lectins in Innate Immunity: Molecular and Structural Basis for Diversity in Self/Non-Self Recognition. Adv. Exp. Med. Biol. (In press). Ahmed, H., and Vasta, G.R. (2007) Unlike mammalian GRIFIN, the zebrafish homologue (DrGRIFIN) represents a functional carbohydrate-binding galectin. Biochem Biophys Res Commun. (In press) Mercer, N., Ahmed, H., Etcheverry, S.B., Vasta, G.R., and Cortizo, A.M. Advanced glycation end products regulate their receptors and induce apoptosis in osteoblast-like cells. Mol. Cell. Biochem. (In press) Schott, E.J., Robledo, J.A.F., Alavi, M.R., and Vasta, G.R. (2007) Susceptibility of Crassostrea ariakensis (Fujita 1913) to Bonamia and Perkinsus spp. infections: Potential for disease transmission between oyster species J. Shellfish Res. (In press) Pecher, W.T., Alavi, M., Schott, E.J., Robledo, J.A.F. Roth, L., Berg, S.T. and Vasta, G.R. (2007) Assessment of the northern distribution range of selected Perkinsus species in eastern oysters (Crassostrea virginica) and hard clams (Mercenaria mercenaria) using PCR-based detection assays. J. Parasitol (In press) Tasumi, S. and Vasta, G.R. (2007) A novel galectin facilitates entry of the parasite Perkinsus marinus into oyster hemocytes. J. Immunol (In press) Alavi, M.R., Schott, E.J., Saito, K. and Vasta, G.R. (2007) Comparative survey of bacterial pathogens associated with Crassostrea virginica and C. ariakensis (Fujita 1913). J. Shellfish Res. (In press) Saito, K., Drgon, T., Krupatkina, D.N., Drgonova, J., Terlizzi, D.E., Mercer, N., and Vasta, G.R. (2007) In vitro encystment and proliferation of Pfiesteria piscicida: Effect(s) of biotic and environmental factor(s) Appl Environ Microbiol. (In press) Smith, L.C., M.S. Quesenberry, A. Milani, K. Saito, K. Fisher, and G.R. Vasta (2007) SpEchinoidin, a C-type lectin expressed by phagocytes from the purple sea urchin (Strongylocentrotus purpuratus) is a component of the innate immune response to lipopolysaccharide (Under revision) Wright, A. C., Robledo, J.A.F., Marsh, A.G. Gauthier, J. D. and G. R. Vasta (2007) Actin gene organization and expression in cultured trophozoites of the protistan parasite Perkinsus marinus (Under revision) Bianchet, M. A., E. W. Odom, G. R. Vasta and L. M. Amzel (2007) Structure of an F-type lectin from striped bass (Morone saxatilis) in complex with its carbohydrate ligand. (In preparation)

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Alavi, M., Robledo, J.A., Saito, K. and Vasta, G.R. (2007) Intracellular survival of Perkinsus marinus in hemocytes of Crassostrea ariakensis and C. virginica: In vitro comparative studies. (In preparation) O’Leary, N., Ahmed, H. and Vasta, G.R. (2007) Hemocyte galectins from the colonial ascidian Clavelina picta: Molecular, biochemical, and functional characterization in innate immunity. (In preparation) Ahmed, H. and Vasta, G.R. (2007) A single chromosome of zebrafish contains multiple galectin genes including two novel inducible galectins syntenic with the human chromosome 17. (In preparation) Henrikson, D., Ahmed, H. and Vasta, G.R. (2007) A novel galectin from the striped bass striped bass (Morone saxatilis): Molecular, biochemical, and functional characterization. (In preparation) Schott, E.J. and Vasta, G.R. (2007) Ascorbate peroxidases of the protistan parasite Perkinsus marinus are targeted to different cellular compartments. (In preparation) Invited Contributions and Book Chapters Palatnik, M., Vasta, G.R., Fink, N.E. and Chiesa, M.E. Protectins and agglutinins in Argentine molluscs: Immunological and immunochemical aspects. In: Immunologic Phylogeny. W.H. Hildemann and W.A. Benedict, eds. Plenum Press, New York, pp. 19-28, 1975. Cohen, E., Ilodi, G.H.U., Vasta, G.R., Minowada, J. and Brahmi, A. Lymphocyte agglutination and hemagglutination by Androctonus and Limulus agglutinins. In: Protides of the Biological Fluids. H. Peeters, ed. Pergamon Press, New York, pp. 417-422, 1979. Cohen, E. and Vasta, G.R. Immunohematological significance of ubiquitous lectins. In: Developmental Immunology: Clinical Problems and Aging. E. Cooper and J. Brazier, eds. Academic Press, New York, pp. 99-108, 1982. Hunt, J.C., Vasta, G.R., McDonald, J.K. and Marchalonis, J.J. Expression of plasma membrane associated dipeptidyl peptidase IV (DPP IV). Activity and immunoglobulin VH-related determinants by human lymphocytes and in vitro leukemia/lymphoma cell lines. In: NonHLA Antigens in Health, Aging and Malignancy: Alan R. Liss, Inc. New York, pp. 191195, 1983. Vasta, G.R. and Marchalonis, J.J. Lectins from tunicates: A biochemical characterization. In: Lectins: Biology, Biochemistry, Clinical Biochemistry, Vol. 3. T.C. Bøg-Hansen, ed. Walter de Gruyter, Berlin, pp. 461-468, 1983. Cheng, T.C., Marchalonis, J.J. and Vasta, G.R. Role of molluscan lectins in recognition processes. In: Recognition Proteins, Receptors and Probes: Invertebrates. E. Cohen, ed. Alan R. Liss, New York. pp 1-15., 1984. Vasta, G.R. and Marchalonis, J.J. Distribution, specificity and macromolecular properties of tunicate plasma lectins, In: Recognition Proteins, Receptors and Probes: Invertebrates. E. Cohen, ed. Alan R. Liss, New York. pp. 125-141, 1984. Cohen, E., Vasta, G.R., Korytnyk W., Petrie, III, C.R. and Sharma, M. Lectins of the limulidae and hemagglutination-inhibition by sialic acid analogs and derivatives. In: Recognition Proteins, Receptors and Probes: Invertebrates E. Cohen, ed. Alan R. Liss, New York. pp.55-69, 1984.

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Wodjani, A. and Vasta G.R. Immunodevelopmental process and aging. Dev. Comp. Immunol. Supplement 3: 253-254, 1984. Vasta, G.R. and Marchalonis, J.J. Immunobiological significance of invertebrate lectins, In: Recognition Proteins, Receptors and Probes: Invertebrates. E. Cohen, ed. Alan R. Liss, New York. pp.177-191, 1984. Vasta, G.R. and Marchalonis, J.J. Comparison of the structure of a galactosyl-binding lectin from the tunicate Didemnum candidum with other putative recognition molecules from invertebrates and vertebrates. In: Lectins: Biology, Biochemistry and Clinical Biochemistry Vol. 4, T.C. Bøg Hansen ed. Walter de Gruyter Berlin pp. 663-669, 1985. Vasta, G.R. Serum and hemocyte-associated lectins of the oyster Crassostrea virginica. In: Lectins: Biology, Biochemistry, Clinical Biochemistry. Vol. 5. T.C.Bøg Hansen ed. Walter de Gruyter, Berlin, pp. 677-686, 1986. Marchalonis, J.J., Warr, G.W., Vasta, G.R. and Ledford, B.E. Molecular recognition of "nonself" determinants: The existence of a superfamily of recognition molecules related to primordial immunoglobulins? In: Receptors in Biological Systems. R. Gorczinski, ed. Academic Press, Canada, Ontario. pp. 45-71, 1986. Vasta, G.R. and Marchalonis, J.J. Invertebrate agglutinins and the evolution of humoral recognition factors. In: Cell Receptors and Cell Communication in Invertebrates. B.A. Cinader, ed. Marcel Dekker, New York, pp. 104-117, 1987. Marchalonis, J.J., Mackel-Vandersteenhoven, A., Vasta, G.R., Schluter, S.F., DeLuca, D., Pandey, J.P. and Wang, A.C. Antigen-binding T-cell receptors: products of new immunoglobulin genes with homologies to segments of immunoglobulin variable regions and putative T cell receptor genes. In: Antigen-Specific T Cell and Factors. J.J. Marchalonis, ed. CRC Press, Boca Raton, FL, Vol. 1, pp. 97-148, 1987. Vasta, G.R. and Pont-Lezica R. Plant and animal lectins. In: Recognition and Assembly of Animal and Plant Extracellular Matrix. W.S. Adair and R.P. Mecham eds. Academic Press, Orlando., pp. 173-245, 1990. Vasta, G.R. Invertebrate lectins, C-reactive and serum amyloid. Structural relationships and evolution. In: Defense Molecules. Marchalonis, J.J. and Reinisch, C.L. Eds., Wiley-Liss, New York, pp. 183-199, 1990. Vasta, G.R. The multiple biological roles if invertebrate lectins: Their participation in non-self recognition mechanisms. In: Phylogenesis of Immune Functions. Cohen, N and Warr, G.W., Eds. CRC Press, Boca Raton, pp. 73-101, 1991. Vasta, G.R. Invertebrate lectins: Distribution, synthesis, molecular biology and function. In: Glycoconjugates: Composition, Structure and Function. Allen, H.J. and Kisailus, E.C. Eds. Marcel Dekker, New York, pp. 593-634, 1992. Cassels, F. J., Odom, E. W. and Vasta, G. R. Hemolymph lectins of the blue crab Callinectes sapidus recognize selected serotypes of its pathogen Vibrio parahaemolyticus . Ann. N.Y. Acad Sci. 712: 324-326, 1994. Ahmed, H., Fink, N.E. and Vasta, G.R. Elasmobranch and teleost fish contain thiol-dependent galactoside binding lectins that are cross-reactive with those identified and characterized in bovine spleen. Ann. N.Y. Acad Sci. 712: 318-320,1994. Elola, M. T. and Vasta, G. R. Lectins from the colonial tunicate Clavelina picta are structurally related to acute phase reactants from vertebrates. Ann. N.Y. Acad Sci. 712: 321323,1994.

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Snowden, A. M. and Vasta, G. R. A dimeric lectin from coelomic fluid of the starfish Oreaster reticulatus cross-reacts with the sea urchin embryonic substrate adhesion protein, echinonectin. Ann. N.Y. Acad Sci. 712: 327-329, 1994. Vasta, G. R., Ahmed, H., Fink, N.E., Elola, M.T., Marsh, A., Snowden, A. and Odom, E.W. Animal lectins as self/non-self recognition molecules: Biochemical and genetic approaches to understanding their biological roles and evolution. Ann. N.Y. Acad Sci. 712: 55-73, 1994. Ahmed, H., Fink, N. E. and Vasta, G. R. A novel solid phase assay for lectin binding: Comparative studies on galactoside binding S-type lectins from fish, amphibian and mammalian tissues. Ann. N.Y. Acad Sci. 712: 315-317, 1994. Vasta, G. R. and Ahmed, H. Lectins from aquatic invertebrates: Strategies and methods for their detection, isolation and biochemical characterization. In: Techniques in Fish Immunology. Vol. 4. Eds: J.S. Stolen et al. SOS Publications. pp 241-258, 1995. Yoshino, T. P. and Vasta, G. R. Parasite-invertebrate host immune interactions. In: Invertebrate Immune Responses. Ed: E. Cooper. Springer-Verlag. Heidelberg, 125-167, 1995. Vasta, G.R., Gauthier, J.D. and Marsh, A.G. Molecular and biochemical adaptations of the protozoan pathogen Perkinsus marinus for its host, Crassostrea virginica: Current research and future perspectives [or “The Best Defense is a Good Offense”]. J. Mar. Biotech. 3: 35-41, 1995 Vasta, G. R. and Ahmed, H. Animal lectins as acute phase reactants. In: Signalling Mechanisms in Protozoa and Invertebrates. Cell Surface-Associated Receptors and their Ligands in Invertebrates and Protists. Eds: W.E.G. Müller and G. Csaba. Springer-Verlag. Heidelberg, 158-182, 1996. Vasta, G. R., Quesenberry, M. S. and Ahmed, H. A lectin from the tunicate Clavelina picta is a homologue of the mannose-binding proteins from vertebrates. In: Modulators of Immune Responses. Eds: J.S. Stolen et al. SOS Publications, New Jersey, 55-74, 1996. Vasta, G. R. Invertebrate Lectins: Their role as self/non-self recognition molecules in the acute phase response. In: New Directions in Invertebrate Immunology. Eds: K. Söderhäll, S. Iwanaga and G.R. Vasta. SOS Publications, New Jersey, 189-224 , 1996. Vasta, G.R. Biotechnological applicationsto shellfish aquaculture and fisheries. Northeastern Research in Aquaculture Center Publications. 7: 4-5, 1997 Vasta, G.R. and Marsh, A.G. Biotechnology of Marine Invertebrates: Current Approaches and Future Directions. In: Biotechnology in Agriculture. Ed. A. Altman. Marcel Decker, New York. 563-583, 1997. Bayne C.J. and Vasta, G.R. Invertebrate Immune Systems In: Encyclopedia of Immunology. Second Edition. Eds. I.M. Roitt and P.J. Delves. Academic Press, London. Vol. 3, p: 1498-1502, 1998. Leffler,M., Greer, J., Belas, R.,Kramer, J.,Place, A.R. , Vasta, G.R., and Zohar, Y. (1998) Molecular Technologies and Pfiesteria Research. Maryland Sea Grant Publ. Pp 35 Vasta, G.R., Ahmed, H., Odom, E.W., Saito, K. and Tasumi, S. (2006) Lectin repertoires in Invertebrates and Ectothermic Vertebrates: Their Roles in Embryogenesis and Innate Immunity. In: “Comprehensive Glycoscience” Section “Molecular Interactions”, Johannes P. Kammerling, Editor–in-Chief, Elsevier, Amsterdam. (In press) Place, A. Robledo, Saito, K. Vasta, GR. (2007) Ichthyocidal activity of Pfiesteria spp and Karlodinium spp: Ecobiology, toxicology, and molecular detection of algal blooms”

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Chapter 36, Part X, for the book “Seafood and Freshwater Toxins. Pharmacology, Physiology, and Detection” Taylor & Francis. Second edition. (In press) Books "New Directions in Invertebrate Immunology" Editor, in collaboration with Drs. K. Söderhäll (Sweden) and S. Iwanaga (Japan). SOS Publications, New Jersey, pp 494, 1996. "Animal Lectins: A Functional View" Editor, in collaboration with Dr. H. Ahmed, Co-Editor. CRC Press, (In preparation). PATENTS Vasta, G.R et al. US Patent Awarded on December 2001"Assessing the Presence of “Dermo” Disease in the Environment by Using a PCR-Based Diagnostic Assay for Perkinsus marinus” Ahmed H. and Vasta G.R US Patent “Galectins as markers for the early diagnostic of prostate cancer” (In process) 2006 Robledo J.A.F. and Vasta, G.R. “Perkinsus as a system for production of recombinant proteins” (In process) 2006 Robledo J.A.F. and Vasta, G.R. “A transfection system for Perkinsus species” (In process) 2006 INVITED PRESENTATIONS (Last 5 years) “C-Type Lectins as Self/Non-self Recognition and Effector Factors in Innate Immunity” Invited Seminar, TIBOTEC Biotech Inc. Host Dr. A. Silva. April 2001 “Dermo” Disease in the Eastern Oyster Crassostrea virginica Caused by Perkinsus marinus: The Role of Iron in Host-Parasite Interactions” Invited Lecture. Comparative Immunology Workshop. Florida International University. March 2002 Host: Dr. Sylvia Smith “In Vitro Culture of Perkinsus atlanticus from Ruditapes decussates” Invited presentation. Annual Meeting for the Clam Aq. Disease Program, University of Algarve, Faro, Portugal, February 2002 Host: Dr. L. Cancela “Lectins in Protochordates and Teleost Fish: Structure-Function Relationships in Innate Immunity” Invited Seminar. IATS, Castellon, Spain. February 2002 Hosts: Drs. Manuel Carrillo y Silvia Zanuy “Protochordates as Model Organisms in Comparative Immunology” Invited Presentation. Charleston, South Carolina NSF Workshop “Evolutionary Immunobiology: New Approaches, New paradigms” Sponsored by NSF. February 2002. Host: Dr. Gregory Warr “Perkinsus Species as Models for Host-Parasite Interactions” Invited Presentation. Charleston, South Carolina NSF Workshop “Evolutionary Immunobiology: New Approaches, New paradigms” Sponsored by NSF. February 2002. Host: Dr. Robert Chapman

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“C-Type Lectins and Recognition of Self/Non-Self” Invited Presentation. Charleston, South Carolina NSF Workshop “Evolutionary Immunobiology: New Approaches, New paradigms” Sponsored by NSF. February 2002. Host: Dr. Gregory Warr “Innate Immunity in Invertebrates: Self/Non-Self Recognition by the Host and Parasite Adaptations for Entry and Survival” Invited Seminar. Graduate School Seminar Series. Medical University of South Carolina Charleston, South Carolina March 2002 Host: Mathew Jenny, MSc “Lectins in Protochordates and Teleost Fish: Structure-Function Relationships in Innate Immunity” Invited presentation to the Symposium “Comparative Immunology” organized by Dr. Edwin L. Cooper, Annual Meeting of the Society of Integrative and Comparative Biology, Annaheim, California. January 2002 “F-lectins: A family of fucose-binding animal lectins with a characteristic sequence motif” Invited Speaker. Glycobiology Interest Group, Johns Hopkins University, March 2002 “Lectin-Mediated Recognition in Innate Immunity: Evolution of Structural Motifs”. Invited Speaker, Symposium: “Phylogeny of Innate Immunity” organized by Dr. Gary Litman. Annual Meeting of the FASEB, New Orleans, April 2002 “A Novel Family of Fucose-Binding Animal Lectins with a Characteristic Sequence Motif and Structural Fold” Invited Speaker. INTERLEC XX Copenhagen, Denmark, May 20-25, 2002 “Innate Immunity in Marine Invertebrates and Fish: Self/Non-Self Recognition” Invited Seminar Speaker. Department of Zoology, University of Palermo, Italy, May 25-30, 2002 “Oxidative Stress and Parasite Adaptations for Intracellular Survival” Invited Seminar Speaker. Department of Zoology, University of Palermo, Italy, May 25-30, 2002 “Innate immunity and disease in invertebrates: Host recognition/effector mechanisms, and parasite adaptations for intracellular survival”. Invited Seminar Speaker. Department of Microbiology. University of Ancona, Italy, May 30, 2002 “F-Lectins: A Novel Family of Fucose-Binding Animal Lectins with a Characteristic Sequence Motif and Structural Fold”. Invited Seminar Speaker. Centre de Biophysique Moleculaire, CNRS, Universite d’ Orleans, France, June 3, 2002. “Molecular Approaches for Diagnosis of “Dermo” Disease and Intervention Strategies” Invited Speaker and Panel Discussion Member. 12th Annual Conference of the Society of Environmental Journalists, Baltimore, Maryland, October 9-13, 2002 “F-lectins: A family of fucose-binding animal lectins with a characteristic sequence motif and structural fold”. Invited Speaker. XVII International Symposium on Glyconjugates, organized by Dr. Avadesha Surolia, Bangalore, India, January 12th – 16th, 2003. “Biochemical and Molecular Characterization of Galectins from Zebrafish (Danio rerio). Notochord-Specific Expression of a Proto Type Galectin During Early Embryogenesis, and Evidence for its Role in Muscle Differentiation”. Invited Speaker. 6th, International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules, organized by Dr. Chitra Mandal, Kolkata, India. January 17-18, 2003 “F-lectins: A family of fucose-binding animal lectins with a characteristic sequence motif and structural fold”, Invited speaker, Gordon Research Conference on Glycobiology, organized by Dr. Rick Cummings, Ventura, CA, March 2-6, 2003.

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“A novel family of fucose-binding animal lectins (F-lectins) with a characteristic sequence motif and structural fold”. Plenary Speaker. Symposium: “Phylogeny of the immune system” Florida International University, Miami , Florida, March 7-9, 2003 “Molecular and structural/functional aspects of carbohydrate recognition in innate immunity”. Plenary Speaker. "The Louis Du Pasquier Symposium on Phylogeny of the Immune System", organized by Dr. Martin Flajnik. Satellite Symposium of the Annual Meeting of the AAI. San Francisco, CA, May 11-12, 2003 “F-lectins from teleost fish and amphibians: Recognition proteins with a characteristic sequence motif and structural fold, involved in innate immunity” Invited Plenary Speaker. 12th European Carbohydrate Symposium, Grenoble, France, July 6-11, 2003 “Innate Immunity: Lectin-Mediated Recognition by the Host, and Parasite Adaptations for Intracellular Survival“ Invited Speaker. National Science Foundation, Arlington, VA, July 24, 2003 “Molecular technologies: Applications to oyster Dermo disease” Plenary speaker. Symposium: “Oyster Disease and Restoration” Organized by NOAA/Sea Grant. Annapolis September 7-9, 2003 “The best defense is a good offense: Protein-carbohydrate interactions in innate immunity, and parasitic adaptations for intracellular survival”. Invited Speaker. Department of Biology. The University of Miami, Miami, Florida, September 15, 2003 “Innate Immunity in Fish: A novel family of fucose-binding animal lectins with a characteristic sequence motif and structural fold”. Keynote Speaker. International Marine Biotechnology Conference, Chiba, Japan, September 21-25, 2003 “Protein-crabohydrate interactions in innate immunity, and parasitic adaptations for intracellular survival” Department of Biological Sciences, University of Tokyo, Tokyo, Japan, September 29, 2003 “Molecular and structural/functional aspects of carbohydrate recognition in innate immunity”. Invited Speaker. Annual Congress of the SAI, Mar del Plata, Argentina, November 2003 “Host-Parasite Interactions: Oxidative Stress and Parasite Adaptations for Intracellular Survival”. Invited Speaker. Annual Congress of the SAI, Mar del Plata, Argentina, November 2003 “La Major Defensa es una Buena Ofensiva: Estrategias Antioxidativas de Parasitos Intracelulares” Invited Speaker. School of Biochemistry, Universidad Nacional de La Plata, Argentina, November 2003 “Factores de Reconocimiento en Inmunidad Innata : Identificacion y Caracterizacion de una Nueva Familia de Lectinas” Invited Speaker. School of Biochemistry, Universidad Nacional de La Plata, Argentina, November 2003 “Mechanisms of Innate Immunity by the Host, and Parasite Adaptations for Intracellular Survival“ Invited Seminar. Universidad Nacional de Buenos Aires, Capital Federal, Buenos Aires, Argentina, December 2003 “Molecular and structural/functional aspects of carbohydrate recognition in innate immunity”. Invited Seminar. Kewalo Laboratory, University of Hawaii, February 2004 “Genus-, species-, and strain-specific molecular probes for apizootiology assessment of Perkinsus spp in natural and farmed oyster populations along the Atlantic coast of USA. Invited contribution. World Aquaculture Society Congress, Honolulu, Hawaii, February 2004

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“Aspectos Moleculares y Estructurales de Factores de Reconocimiento en Inmunidad Innata”. Invited Seminar. Universidad Nacional de Oaxaca, Oaxaca, Mexico , February 2004. “Mecanismos y Evolucion de Factores de Reconocimiento en Inmunidad Innata”. Invited Speaker. Annual Congress of the Mexican Society of Immunology. Oaxaca, Mexico , February 2004. “Disease resistance in the oyster Crassostrea ariakensis: In vivo and in vitro susceptibility to infection with Perkinsus spp and Bonamia spp” Speaker at the Oyster Demographic Modeling workshop, DNR/PRFC, Oyster Environmental Impact Statement, Horn Point, MD, October 2004 “Lectins in Teleosts: Recognition/effector factors in response to infectious challenge” World Congress of Fish Biology, Manaus, Brazil, November 2004 “Inmunidad Innata: Aspectos Estructurales, Funcionales y Evolutivos” Invited Plenary speaker Annual Joint Meeting of the Sociedad Argentina de Inmunologia and Sociedad de Investigaciones Clinicas, Mar del Plata, Argentina November 2004 “Innate Immunity: Breakfast with the experts” Discussion session; Annual Joint Meeting of the Sociedad Argentina de Inmunologia and Sociedad de Investigaciones Clinicas, Mar del Plata, Argentina, November 2004 “Lectins and Innate Immunity: Structural and Functional Aspects” Invited Plenary speaker, Annual Congress of the Italian Society of Developmental and Comparative Immunology, Trapani, Italy, February 2005 “The Eastern Oyster/Perkinsus spp as a Model for intracellular Parasitism” Invited Seminar University of Viterbo, Italy, February 2005 “Protein-Sugar Interactions in Innate Immunity: Structure, Function and Evolution” Invited Seminar Department of Biology, North Carolina State University, Charlotte, NC, March 2005 “The galectin repertoire of zebrafish (Danio rerio) during early embryogenesis: Biochemical and molecular characterization” Invited speaker Gordon Research Conference “Glycobiology” Ventura, CA, March 2005 “Protein-Sugar Interactions in Innate Immunity: Structure, Function and Evolution” Invited Seminar Department of Biology, Cornell University, Ithaca, NY, March 2005 “Interacciones Proteina-Carbohidrato en Inmunidad Innata: Aspectos Estructurales, Funcionales y Evolutivos” Invited Seminar Leloir Institute, Buenos Aires, Argentina. April 2005 “Inmunidad Innata: Aspectos Estructurales, Funcionales y Evolutivos” Invited Plenary speaker, Symposium “Innate Immunity” Jornadas Bioquímicas Bonaerenses, Mar del Plata, Argentina. May 2005 “Interacciones Parásito-Hospedador: Aspectos Bioquímicos y Moleculares" Invited Plenary speaker. XIII Congreso de la Asociación Mexicana de Profesores de Bioquímica, Facultad de Medicina de la UNAM, DF, Mexico, August, 2005 "Inmunidad Innata: aspectos estructurales y funcionales". Invited Plenary speaker XXXII Taller de Actualización Bioquímica, (8-10 de Agosto) Facultad de Medicina de la UNAM, DF, Mexico, August, 2005 “Structure, Function and Evolution of Animal Lectin Repertories: Their roles in Innate Immunity” Invited Seminar, Unité de glycobiologie structurale et fonctionnelle, UMR CNRS, Université de Lille, France October 2005

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“Marine Biotechnology: The Next Revolution? “ Invited Conference for the Series "A sea of resources", organized by the Instituto de Investigaciones Marinas, CSIC, and the Fundación Areces, Vigo, Spain, October 2005 “Structural and Evolutionary Aspects of Animal Lectins: Diversity in Glycan Recognition” Invited speaker. Annual Conference of the Society for Glycobiology, Boston November 2005 “La major defensa es una buena ofensiva: Estrategias de parasitos intracelulares contra el estres oxidativo” Invited Plenary speaker XVII Latinamerican Congress of Parasitology, Mar del Plata, Argentina. November 2005 "Lectin Repertories in Invertebrates and Ectothermic Vertebrates: Their Roles in Embryogenesis and Innate Immunity” Invited seminar, Glycobiology Interest Group, Johns Hopkins University. December 2005 “Antioxidant Activities in the Intracellular Protistan Parasite Perkinsus marinus” Invited speaker, Biomedical & Comparative Immunology Symposium (FIU), Miami. March 2006 “Structural, Functional and Evolutionary Aspects of Animal Lectins in Innate Immunity and Development: Diversity in Glycan Recognition” Invited speaker, Biomedical & Comparative Immunology Symposium (FIU), Miami. March 2006 “Biotecnologia Marina: La Proxima Revolucion” Invited Conference, organized by the Universidad de Mallorca, Grupo Serra (Club Ultima Hora), and the Fundación Areces, Palma de Mallorca, Spain, March 2006 “Biotecnologia Marina: La Proxima Revolucion” Invited Conference, Sede Central de la Fundación Areces, Madrid, Spain, March 2006 “Diversificación de los Repertorios de Lectinas en Inmunidad Innata” Invited speaker for the Symposium No 3.4: “Mecanismos de Reconocimiento en Respuesta Inmune Innata”. XVII National Congress of the Mexican Society of Immunology, Chihuahua, Mexico, May 2006. “Animal lectins in innate immunity: Structural, functional and evolutionary aspects” Invited speaker, Innate Immunity Aegean Conferences, Corfu, Greece, June 2006 “A tribute to Elias Cohen, Ph.D.: Researcher, teacher, musician, mentor, and friend” Invited presentation at the Session “History of the ISDCI” 10th Congress of the International Society of Comparative and Developmental Immunology, Charleston, South Carolina, July 2006 “Lectins in the Eastern Oyster Crassostrea virginica: Recognition and Effector Roles in Perkinsus spp Infections” Invited Speaker at the Workshop: “Immunity of Mollusks” 10th Congress of the International Society of Comparative and Developmental Immunology, Charleston, South Carolina, July 2006 “Structural, Functional and Evolutionary Aspects of Lectins in Innate Immunity: The First Trench (and a Trojan Horse?) ” Invited Seminar, Karolinska Institute, Stockholm, Sweden, October 2006 “Aspectos Estructurales, Funcionales y Evolutivos de las Interacciones Proteina-Carbohidrato en Inmunidad Innata” Invited Seminar, Louis Pasteur Institute and Universidad de la Republica, Montevideo, Uruguay, November 2006 “Lectinas en inmunidad innata: La primera trinchera (y el caballo de Troya)” Leonardo Satz Memorial Conference, Annual Joint Meeting of the Sociedad Argentina de Inmunologia and Sociedad de Investigaciones Clinicas, Mar del Plata, Argentina, November 2006

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“Interacciones Proteina-Carbohidrato en Inmunidad Innata: Aspectos Estructurales, Funcionales y Evolutivos” VIII Congreso and XXVI Reunión Anual Sociedad de Biología, Rosario, Argentina, December 2006 “Lectins in Innate Immunity of Shellfish and Finfish: Structural, Functional and Evolutionary Aspects”. Keynote Lecture. International Marine Biotechnology Conference, Eilat, Israel, March 10-16, 2007 “"Self/Non-Self Recognition by Lectins in Innate Immunity: The First Barrier (and the Trojan Horse?)"”. Invited Seminar, Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel. Host: Nathan Sharon. March 2007

PRESENTATIONS TO ADVISORY COMMITTEES/SITE VISITING PANELS “Research Core: Harmful Algae”. MBFS Center Proposal. NIEHS Site Visit, Baltimore, April 1999 “Service Core Facility for Culture of Pfiesteria piscicidaand related Dinoflagellate species”. MBFS Center Proposal. NIEHS Site Visit, Baltimore, April 1999 “Genetic Characterization of dinoflagellate Pfiesteria piscicidaand related species”. NIEHS External/Internal Advisory Committee Meeting, Baltimore, May 1999 “Recent Progress in the Core Facility for Culture of Pfiesteria piscicidaand related Dinoflagellate species”. NIEHS External/Internal Advisory Committee Meeting, Baltimore, May 1999 “PCR-based detection assay for the dinoflagellate Pfiesteria piscicida” NIEHS External/Internal Advisory Committee Meeting, Baltimore, November 1999 “Development and Characterization of a Flask Bioassay for the Induction of Toxicity in Pfiesteria piscicida” NIEHS External/Internal Advisory Committee Meeting, Baltimore, November 1999 “Disease in Aquaculture and the Environment” Congressional Staff Members, COMB, Baltimore, May 2000 “Genomics approaches to Perkinsus species.” National Science Foundation site visit, organized by Shil DasSarma, COMB, Baltimore May 2004.

ECONOMIC DEVELOPMENT ACTIVITIES Certification of oyster and clam stocks and seed for oyster farms, based on our diagnostic PCR based assays. Development of rapid diagnostic assays for Pfiesteria piscicida, supported by American Standard Corporation. Cooperation program with collaborator at TIBOTEC, a drug design company from Belgium, for anti-parasitic drugs is under development. Cooperation program with QUIAGEN in the adaptation of DNA extraction kits to samples from the marine environment Development of novel molecular assays for diagnosis of Perkinsus species (Patent awarded; Inventor)

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Development of novel molecular assays for diagnosis and prognosis of prostate and breast cancer (Patent in process; Co-Inventor)

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