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					Table (E)T-2MRI data for patients with encephalopathy
    Pt # Scan date (days)                         Abnormal signal Lesion                               Atrophy                T1               T2                 FLAIR              DWI         ADC (x10-6 mm3/s)            GD
      1            1                                       None                                                                                                                                                               ne
                   5                 lt. hemispheric&rt. F. WM, GM, lt. BG, lt. Th.                                            L         H (U fiber>GM)      H (U fiber>GM)       H (U fiber)           L (110)               ne
                  14                      lt. hemispheric WM, GM, lt BG, lt Th                                                 L          H (GM, WM)          H (GM, WM)           H (GM)               I (880)               ne
                  70                         lt. hemispheric WM, lt BG, lt. Th                 severe, lt. hemispheric         L          H (GM, WM)          H (GM, WM)              I                                       ne

     2       2 years before                            bil. PVL, Th                                                      L (PVL, Th)      H (PVL, Th)              ne                 ne                                      ne
                    2                                  bil. PVL, Th                                                      L (PVL, Th)      H (PVL, Th)              ne                 ne                                      ne
                    7       bil F., P. WM, GM (sparing peri-Rolandic region), bil. PVL, Th                                    L          H (U fiber>GM)            ne             H (U fiber)            L (260)          No enhance
                   14       bil F., P. WM, GM (sparing peri-Rolandic region), bil. PVL, Th                                    L            H (SCWM)            H (SCWM)            H (GM)             sl H (1100)             ne
                  180                         bil F., P. WM, bil. PVL, Th                              severe                 I             sl H (WM)          sl H (WM)               I                                      ne

     3              5                        bil. F., P. WM (sparing peri-Roland)                                              L          sl H (U-fiber)      sl H (U-fiber)     H (SCWM)                                      ne
                   12                  bil. F., P. WM, GM (sparing peri-Roland), GP                                            L            H (SCWM)            H (SCWM)         H (GM, GP)                                    ne
                   24                                    bil. F., P. WM, GP                            severe                  L             H (WM)              H (WM)              I                                         ne

     4              7                       bil. F., P. WM (sparing peri-Roland)                                               L          H (U-fiber)              ne             H (SCWM)                                     ne
                   12                    bil. F., P. WM, GM (sparing peri-Roland)                                              L         H (GM, SCWM)              ne              H (GM)                                      ne
                   30                    bil. F., P. WM, GM (sparing peri-Roland)                     moderate                 L         H (GM, SCWM)              ne                 I                                        ne

     5              7                    bil. F., P. WM, GM (sparing peri-Roland)                                              I            sl H (GM)              ne             H (SCWM)              L (290)                ne
                   13                        bil. F., P. GM (sparing peri-Roland)                                              I                 I                  I             sl H (GM)             I (867)                ne
                   27                                         none                                    moderate                                                                                                                 ne

     6              5                    bil. F., P. WM, GM (sparing peri-Roland)                                              L         H (U fiber>GM)      H (SCWM>GM)          H (SCWM)                                No enhance
                   25                    bil. F., P. WM, GM (sparing peri-Roland)                        mild                  L             H (WM)           H (GM, WM)              I                                       ne

     7              6                    bil. F., P. GM, WM (sparing peri-Roland)                                              I            sl H (GM)           sl H (GM)         H (SCWM)                  L                  ne
                   13                                      none                                                                I                ne                   I                I                                        ne

     8              6                      bil. F., P. WM (sparing peri-Roland)                                                I           H (U fiber)         H (U fiber)        H (SCWM)               L (167)          No enhance
                   14                       bil F., P. GM (sparing peri-Roland)                         mild                   I               I               sl H (GM)           H (GM)               I (1050)              ne
                   22                                       none                                        mild                   I               I                    I                 I                   I (910)             ne
                   95                                       none                                      moderate                                                                                                                ne

     9              6                        bil. F., P. WM (sparing peri-Roland)                                              I           H (U fiber)         H (U fiber)        H (U fiber)           L (388)                ne
                   14                     bil F., P. GM, WM (sparing peri-Roland)                       mild                   I         sl H (GM, WM)       sl H (GM, WM)            I                                        ne
                   28                        bil F., P. GM (sparing peri-Roland)                      moderate                 I            sl H (GM)           sl H (GM)             I                                        ne

     10             6                                     bi F. WM                                                             I           H (U fiber)         H (U fiber)        H (SCWM)              L (341)                ne
                   10                                  bi F. GM, WM                                                            I         sl H (GM, WM)       sl H (GM, WM)            I                                        ne
                   30                                     bi F. GM                                       mild                  I            sl H (GM)           sl H (GM)             I                                        ne

     11             2                                      none                                                                                                                                          I (816)               ne
                    8                          bil. WM (sparing peri-Roland)                                              L (U fiber)      H (U fiber)         H (U fiber)        H (SCWM)               L (311)               ne
                   15                       bil. WM, GM (sparing peri-Roland)                                                 L          H (SCWM>GM)         H (SCWM>GM)              I               sl H (1120)              ne
                   22                          bil. WM (sparing peri-Roland)                            mild                  L             H (WM)              H (WM)                I               sl H (1070)              ne
                   60                       bil. GM, WM (sparing peri-Roland)                         moderate                L             H (WM)              H (WM)                I                                        ne

     12             2                                       none                                                                                                                                         I (900)               ne
                    9                       bil. F., P. WM (sparing peri-Roland)                                               I          sl H (U fiber)       H (SCWM)           H (SCWM)              L (284)                ne
                   17                    bil. F., P. WM, GM (sparing peri-Roland)                       mild                   I             H (WM)             H (WM)             H (GM)             sl H (1120)              ne
                   40                       bil. F., P. WM (sparing peri-Roland)                       severe                  L             H (WM)             H (WM)                I               sl H (1080)              ne

     13             5                                    bil. F WM                                                             I                 I             H (SCWM)           H (SCWM)               L (447)               ne
                   11                                       none                                                               I                 I                 I                  I                 I (1030)               ne
                   30                                       none                                         mild                  I                 I                 I                  I                  I (998)               ne

     14             1                                        none
                    3                                     bil. F WM                                                            I                 I                  I             H (SCWM)               L (327)               ne
                    9                                  bil. F GM, WM                                                           I           H (GM, WM)         H (GM, WM)           H (GM)                I (960)               ne
                   16                                     bil. F WM                                      mild                  I            sl H (WM)          sl H (WM)              I                 I (1020)               ne

     15             5                   bil. F, P GM, WM (sparing peri-Roland), Th                                           sl L        H (U fiber>GM)      H (U fiber>GM)       H (SCWM)                                     ne
                   13                      bil. F, P GM, WM (sparing peri-Roland)                                              I          H (GM, WM)          H (GM, WM)           H (GM)                                      ne
                   20                      bil. F, P GM, WM (sparing peri-Roland)                        mild                  I          H (GM, WM)          H (GM, WM)              I                                        ne
                   50                         bil. F, P WM (sparing peri-Roland)                         mild                  I             H (WM)              H (WM)               I                                        ne

     16             6                   bil. F, P GM, WM (sparing peri-Roland), Th                                             I         H (U fiber>GM)            ne             H (SCWM)                                     ne
                   10                      bil. F, P GM, WM (sparing peri-Roland)                                              I          H (GM, WM)               ne              H (GM)                                      ne
                   17                         bil. F, P WM (sparing peri-Roland)                        mild                   I             H (WM)                ne                 I                                        ne
                   45                         bil. F, P WM (sparing peri-Roland)                       severe                sl L            H (WM)                ne                 I                                        ne

     17                5                       bi F., P. WM (sparing peri-Roland)                                              ne        H (U fiber>GM)      H (U fiber>GM)     H (SCWM)                     L                 ne
                      14                       bi F., P. WM (sparing peri-Roland)                                               L           H (GM, WM)         H (GM, WM)         H (GM)                                       ne
                      74                                                                                  mild                  I                I                   I                I                                        ne
  Scan date (days after initial seizure); DWI, diffusion-weighted imaging; ADC, apparent diffuion coefficient value in affected white matter; I, isointensity; H, high intensity; L, low intensity; sl, slightly; ne, not examined;
  F., frontal; P., parietal; WM, white matter; SCWM, subcortical white matter; GM, gray matter; lt., left; BG, basal ganglia; Th, thalamus; PVL, periventricular leukomalacia;

				
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posted:11/27/2013
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