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Table st1_ XLSX - mBio

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Table st1_ XLSX - mBio Powered By Docstoc
					Z value   Gene SymbolAccession   Gene Name                     GO Molecular Function
-2.30     76P        NM_014444                                 structural constituent of cytoskeleton;microt
                                 Gamma-tubulin complex component 4;TUBGCP4;ortholog
-2.40     AAAS       NM_015665   Aladin;AAAS;ortholog
-2.03     AASS       NM_005763                                 oxidoreductase
                                 Saccharopine dehydrogenase;AASS;ortholog activity
2.45      ABCB9      NM_019624                                 ATPase activity, coupled to transmembrane
                                 ATP-binding cassette sub-family B member 9;ABCB9;ortholog
-2.43     ABCC3      NM_003786                                 ATPase transporter 2;ABCC3;ortholog
                                 Canalicular multispecific organic anionactivity, coupled to transmembrane
-2.77     ABCG2      NM_004827                                 transmembrane transporter activity
                                 ATP-binding cassette sub-family G member 2;ABCG2;ortholog
3.13      ABHD1      NM_032604                                 hydrolase activity
                                 Abhydrolase domain-containing protein 1;ABHD1;ortholog
2.64      ABHD14A    NM_015407                                 serine-type peptidase activity
                                 Abhydrolase domain-containing protein 14A;ABHD14A;ortholog
-2.25     ABHD14B    NM_032750                                 serine-type peptidase activity
                                 Abhydrolase domain-containing protein 14B;ABHD14B;ortholog
10.29     ABHD3      NM_138340                                 hydrolase activity
                                 Abhydrolase domain-containing protein 3;ABHD3;ortholog
-2.46     ABLIM1     NM_002313                                 structural constituent of cytoskeleton
                                 Actin-binding LIM protein 1;ABLIM1;ortholog
2.19      ACAA1      NM_001607                                 transferase activity
                                 3-ketoacyl-CoA thiolase, peroxisomal;ACAA1;ortholog
-2.06     ACADL      NM_001608                                 dehydrogenase, mitochondrial;ACADL;ortho
                                 Long-chain specific acyl-CoA oxidoreductase activity
-2.33     ACOT7      NM_007274                                 hydrolase activity, acting on ester
                                 Cytosolic acyl coenzyme A thioester hydrolase;ACOT7;orthologbonds
2.58      ACP1       NM_004300                                 phosphoprotein phosphatase activity;phosph
                                 Low molecular weight phosphotyrosine protein phosphatase;ACP1;ortholo
-2.93     ACP5       NM_001611   Tartrate-resistant acid phosphatase type 5;ACP5;ortholog
-2.15     ACPL2      NM_152282   Acid phosphatase-like protein 2;ACPL2;ortholog
2.09      ACSL6      NM_015256                                 ligase activity
                                 Long-chain-fatty-acid--CoA ligase 6;ACSL6;ortholog
-2.64     ACTB       NM_001101                                 structural constituent of cytoskeleton
                                 Actin, cytoplasmic 1;ACTB;ortholog
2.75      ACTG2      NM_001615                                  muscle;ACTG2;ortholog
                                 Actin, gamma-enteric smoothstructural constituent of cytoskeleton
3.06      ACTL6      NM_016188                                 structural
                                 Actin-like protein 6B;ACTL6B;ortholog constituent of cytoskeleton
2.18      ACTN2      NM_001103   Alpha-actinin-2;ACTN2;orthologstructural constituent of cytoskeleton;actin b
-2.59     ACTR2      NM_005722                                 structural
                                 Actin-related protein 2;ACTR2;ortholog constituent of cytoskeleton
-2.93     ACTR3      NM_005721                                 structural
                                 Actin-related protein 3;ACTR3;ortholog constituent of cytoskeleton
7.69      ACVR2      NM_001616                                 transmembrane receptor protein kinase activ
                                 Activin receptor type-2A;ACVR2A;ortholog
-2.52     ACY1       NM_000666   Aminoacylase-1;ACY1;ortholog  metallopeptidase activity
2.63      ADAL       XM_091156                                 hydrolase activity;deaminase activity
                                 Adenosine deaminase-like protein;ADAL;ortholog
-2.44     ADAMTS1    NM_006988                                 metallopeptidase activity
                                 A disintegrin and metalloproteinase with thrombospondin motifs 1;ADAMT
-2.13     ADAMTS14 NM_080722                                   metallopeptidase activity
                                 A disintegrin and metalloproteinase with thrombospondin motifs 14;ADAM
2.73      ADAMTS6    NM_014273                                 metallopeptidase activity
                                 A disintegrin and metalloproteinase with thrombospondin motifs 6;ADAMT
10.74     ADC        NM_052998                                 carboxy-lyase activity
                                 Arginine decarboxylase;ADC;ortholog
-2.37     ADD3       NM_016824   Gamma-adducin;ADD3;ortholog   structural constituent of cytoskeleton;actin b
2.97      ADH1C      NM_000669                                 oxidoreductase
                                 Alcohol dehydrogenase 1C;ADH1C;ortholog activity
3.26      ADH6       NM_000672                                 oxidoreductase activity
                                 Alcohol dehydrogenase 6;ADH6;ortholog
5.50      ADI1       NM_018269                                 oxidoreductase activity
                                 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase;ADI1;ortholog
2.81      ADIPOR1    NM_015999                                 receptor activity
                                 Adiponectin receptor protein 1;ADIPOR1;ortholog
2.84      ADNP       NM_015339   Activity-dependent neuroprotector homeobox protein;ADNP;ortholog
-2.13     ADPRTL1    NM_006437                                 protein binding;serine-type endopeptidase in
                                 Poly [ADP-ribose] polymerase 4;PARP4;ortholog
2.62      AFAF       XM_035953   Acrosome formation-associated factor;AFAF;ortholog
3.78      AGER       NM_001136                                 receptor activity
                                 Advanced glycosylation end product-specific receptor;AGER;ortholog
-2.74     AGL        NM_000028                                 transferase activity, transferring glycosyl gro
                                 Amylo-alpha-1,6-glucosidase;AGL;ortholog
4.13      AGPAT2     NM_006412                                 acyltransferase activity
                                 1-acyl-sn-glycerol-3-phosphate acyltransferase beta;AGPAT2;ortholog
-2.49     AGXT       NM_000030                                 transaminase activity
                                 Serine--pyruvate aminotransferase;AGXT;ortholog
2.80      AHCY       NM_000687                                 hydrolase activity
                                 Adenosylhomocysteinase;AHCY;ortholog
-2.73     AIPL1      NM_014336   Aryl-hydrocarbon-interacting protein-like 1;AIPL1;ortholog
2.69      AK1        NM_000476                                 1;AK1;ortholog
                                 Adenylate kinase isoenzyme nucleotide kinase activity
-2.57     AKR7A2     NM_003689                                 oxidoreductase activity
                                 Aflatoxin B1 aldehyde reductase member 2;AKR7A2;ortholog
2.70      ALAS1      NM_000688                                 transferase activity
                                 5-aminolevulinate synthase, nonspecific, mitochondrial;ALAS1;ortholog
-2.32     ALAS2      NM_000032                                 transferase activity
                                 5-aminolevulinate synthase, erythroid-specific, mitochondrial;ALAS2;ortho
-2.72     ALDH1B1    NM_000692                                 oxidoreductase activity
                                 Aldehyde dehydrogenase X, mitochondrial;ALDH1B1;ortholog
-2.91     ALDH2      NM_000690                                 oxidoreductase activity
                                 Aldehyde dehydrogenase, mitochondrial;ALDH2;ortholog
-2.23   ALDH9A1    NM_000696                                   oxidoreductase activity
                               4-trimethylaminobutyraldehyde dehydrogenase;ALDH9A1;ortholog
6.64    ALDOA      NM_000034                                   lyase activity
                               Fructose-bisphosphate aldolase A;ALDOA;ortholog
-2.27   ALKBH      NM_006020   Alkylated DNA repair protein alkB homolog 1;ALKBH1;ortholog
2.57    ALS2CR17   NM_198945                                   protein binding
                               Neurobeachin-like protein 1;NBEAL1;ortholog
-2.64   ALS2CR3    NM_015049   Trafficking kinesin-binding protein 2;TRAK2;ortholog
-2.48   ALS2CR8    NM_024744   Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 pro
3.06    ALX1       NM_006982                                   transcription factor activity;transcription facto
                               ALX homeobox protein 1;ALX1;ortholog
-2.96   AMDHD2     NM_015944                                   deacetylase deacetylase;AMDHD2;ortholog
                               Putative N-acetylglucosamine-6-phosphateactivity
3.48    AMPD3      NM_000480   AMP deaminase 3;AMPD3;ortholog  hydrolase activity;deaminase activity
-2.45   AMT        NM_000481                                   oxidoreductase activity
                               Aminomethyltransferase, mitochondrial;AMT;ortholog
-2.09   ANAPC1     NM_022662                                     subunit 1;ANAPC1;ortholog
                               Anaphase-promoting complexligase activity
-3.27   ANGEL2     NM_144567   Protein angel homolog 2;ANGEL2;ortholog
2.74    ANKRD10    NM_017664   Ankyrin repeat domain-containing protein 10;ANKRD10;ortholog
-2.34   ANKRD31    XM_293911   Ankyrin repeat domain-containing protein 31;ANKRD31;ortholog
-2.68   ANP32C     NM_012403                                   protein binding;phosphatase inhibitor activity
                               Acidic leucine-rich nuclear phosphoprotein 32 family member C;ANP32C;o
-2.22   ANPEP      NM_001150   Aminopeptidase N;ANPEP;ortholog metallopeptidase activity
-2.21   AP3B1      NM_003664   AP-3 complex subunit beta-1;AP3B1;ortholog
3.37    APC        NM_000038                                   structural constituent
                               Adenomatous polyposis coli protein;APC;ortholog of cytoskeleton;microt
2.58    APEH       NM_001640                                   serine-type peptidase
                               Acylamino-acid-releasing enzyme;APEH;ortholog activity
2.62    APEX2      NM_014481                                   site) lyase 2;APEX2;ortholog
                               DNA-(apurinic or apyrimidinic exodeoxyribonuclease activity;endodeoxyrib
-2.17   APG12L     NM_004707   Autophagy-related protein 12;ATG12;ortholog
-3.17   APOA2      NM_001643                                   lipid transporter activity;transmembrane tran
                               Apolipoprotein A-II(1-76);APOA2;ortholog
-2.56   APOC4      NM_001646   Apolipoprotein C-IV;APOC4;ortholog
-2.51   APOL1      NM_003661                                   lipid
                               Apolipoprotein L1;APOL1;ortholog transporter activity;transmembrane tran
-2.93   APOL2      NM_030882                                   lipid
                               Apolipoprotein L2;APOL2;ortholog transporter activity;transmembrane tran
2.10    APOL5      NM_030642                                   lipid
                               Apolipoprotein L5;APOL5;ortholog transporter activity;transmembrane tran
3.19    AQP3       NM_004925   Aquaporin-3;AQP3;ortholog transmembrane transporter activity
2.44    AR         NM_000044   Aldose reductase;AKR1B1;orthologoxidoreductase activity
-2.86   ARF1       NM_001658                                   GTPase activity;protein binding
                               ADP-ribosylation factor 1;ARF1;ortholog
-2.23   ARFIP1     NM_014447   Arfaptin-1;ARFIP1;ortholog protein binding;small GTPase regulator activ
-3.45   ARHE       NM_005168                                   GTPase activity;protein
                               Rho-related GTP-binding protein RhoE;RND3;ortholog binding
-3.26   ARHGAP1    NM_004308                                   protein binding;small GTPase regulator activ
                               Rho GTPase-activating protein 1;ARHGAP1;ortholog
-2.18   ARHGAP18   NM_033515                                   protein binding;small GTPase regulator activ
                               Rho GTPase-activating protein 18;ARHGAP18;ortholog
2.50    ARHGAP6    NM_001174                                   structural constituent of
                               Rho GTPase-activating protein 6;ARHGAP6;ortholog cytoskeleton
3.65    ARHGDIA    NM_004309                                   receptor binding;small
                               Rho GDP-dissociation inhibitor 1;ARHGDIA;ortholog GTPase regulator act
-2.00   ARHGDIB    NM_001175                                   receptor binding;small
                               Rho GDP-dissociation inhibitor 2;ARHGDIB;ortholog GTPase regulator act
3.13    ARL2       NM_001667                                   GTPase activity;protein
                               ADP-ribosylation factor-like protein 2;ARL2;ortholog binding
-2.25   ARPC3      NM_005719                                   structural constituent of cytoskeleton
                               Actin-related protein 2/3 complex subunit 3;ARPC3;ortholog
-2.70   ARPC4      NM_005718                                   structural constituent of cytoskeleton
                               Actin-related protein 2/3 complex subunit 4;ARPC4;ortholog
3.10    ARPC5      NM_005717                                   structural constituent of cytoskeleton
                               Actin-related protein 2/3 complex subunit 5;ARPC5;ortholog
3.20    ARPP-19    NM_006628   cAMP-regulated phosphoprotein 19;ARPP19;ortholog
-2.78   ARRDC1     NM_152285   Arrestin domain-containing protein 1;ARRDC1;ortholog
3.13    ARSD       NM_001669                                   h
                               Arylsulfatase D;ARSD;orthologydrolase activity
2.45    ARSI       XM_291139   Arylsulfatase I;ARSI;ortholog hydrolase activity
-2.11   ASPA       NM_000049   Aspartoacylase;ASPA;ortholog    metallopeptidase activity;deacetylase activit
2.53    ASPH       NM_004318                                   oxidoreductase activity
                               Aspartyl/asparaginyl beta-hydroxylase;ASPH;ortholog
3.32    ASPHD1     NM_181718                                   oxidoreductase activity
                               Aspartate beta-hydroxylase domain-containing protein 1;ASPHD1;ortholog
-2.17   ATAD1      NM_032810                                   hydrolase activity
                               ATPase family AAA domain-containing protein 1;ATAD1;ortholog
-2.08   ATAD2      NM_014109                                   hydrolase activity
                               ATPase family AAA domain-containing protein 2;ATAD2;ortholog
-2.06   ATF6       NM_007348                                   transcription factor activity;transcription facto
                               Processed cyclic AMP-dependent transcription factor ATF-6 alpha;ATF6;o
-2.26   ATF7IP2    NM_024997   Activating transcription factor 7-interacting protein 2;ATF7IP2;ortholog
3.58    ATM        NM_138293                                   protein kinase activity;nucleotide kinase acti
                               Serine-protein kinase ATM;ATM;ortholog
3.41    ATP10A     NM_024490                                   hydrolase activity;transmembrane transporte
                               Probable phospholipid-transporting ATPase VA;ATP10A;ortholog
2.41    ATP2A1     NM_004320                                   hydrolase activity;cation 1;ATP2A1;ortholog
                               Sarcoplasmic/endoplasmic reticulum calcium ATPase transmembrane tran
2.84    ATP5S      NM_015684                                   cation transmembrane transporter activity;hy
                               ATP synthase subunit s, mitochondrial;ATP5S;ortholog
5.88    ATP5SL     NM_018035   ATP synthase subunit s-like protein;ATP5SL;ortholog
-2.66   ATP6V1A    NM_001690                                   hydrolase A;ATP6V1A;ortholog
                               V-type proton ATPase catalytic subunit activity;cation transmembrane tran
-2.36   ATP6V1B1   NM_001692                                   hydrolase isoform;ATP6V1B1;ortholog
                               V-type proton ATPase subunit B, kidneyactivity;cation transmembrane tran
-3.30   ATP6V1D    NM_015994                                   hydrolase activity;cation
                               V-type proton ATPase subunit D;ATP6V1D;ortholog transmembrane tran
4.37    ATP7B      NM_000053                                   h
                               WND/140 kDa;ATP7B;orthologydrolase activity;cation transmembrane tran
2.23    ATP8B3     NM_138813                                   hydrolase activity;transmembrane
                               Probable phospholipid-transporting ATPase IK;ATP8B3;ortholog transporte
-2.09   ATXN2L     NM_007245                                   RNA binding
                               Ataxin-2-like protein;ATXN2L;ortholog
-2.03   AURKB      NM_004217                                   protein kinase activity
                               Serine/threonine-protein kinase 12;AURKB;ortholog
2.04    AX2R       XM_371738   Annexin-2 receptor;AX2R;ortholog
-2.55   AXIN1      NM_003502   Axin-1;AXIN1;ortholog           protein binding;small GTPase regulator activ
3.11    B3GAT1     NM_018644                                   transferase activity, transferring glycosyl gro
                               Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;B3GA
2.17    BACH2      NM_021813                                    BACH2;BACH2;ortholog
                               Transcription regulator proteintranscription factor activity;transcription facto
-3.00   BAGE4      NM_181704   B melanoma antigen 4;BAGE4;ortholog
-2.32   BAK1       NM_001188                                   receptor binding
                               Bcl-2 homologous antagonist/killer;BAK1;ortholog
7.06    BARX1      NM_021570                                   transcription factor
                               Homeobox protein BarH-like 1;BARX1;ortholog activity;transcription facto
-2.47   BARX2      NM_003658                                   transcription factor
                               Homeobox protein BarH-like 2;BARX2;ortholog activity;transcription facto
-3.09   BAX        NM_004324                                   receptor
                               Apoptosis regulator BAX;BAX;ortholog binding
-2.95   BBS7       NM_018190   Bardet-Biedl syndrome 7 protein;BBS7;ortholog
-3.41   BCAN       NM_021948   Brevican core protein;BCAN;ortholog
2.12    BCHE       NM_000055   Cholinesterase;BCHE;ortholog    hydrolase activity, acting on ester bonds
-2.23   BCOR       NM_017745   BCL-6 corepressor;BCOR;ortholog
6.07    BDP1       NM_018429                                   translation homolog;BDP1;ortholog
                               Transcription factor TFIIIB component B'' factor activity, nucleic acid bindin
2.40    BET1       NM_005868   BET1 homolog;BET1;orthologSNAP receptor activity
-2.87   BFAR       NM_016561   Bifunctional apoptosis regulator;BFAR;ortholog
2.67    BGN        NM_001711   Biglycan;BGN;ortholog           receptor activity
-3.20   BHC80      NM_016621                                   ubiquitin-protein ligase activity
                               PHD finger protein 21A;PHF21A;ortholog
-2.81   BICD2      NM_015250   Protein bicaudal D homolog 2;BICD2;ortholog
2.69    BIK        NM_001197   Bcl-2-interacting killer;BIK;ortholog
2.27    BIN1       NM_004305   Myc box-dependent-interacting protein 1;BIN1;ortholog
-2.39   BIN2       NM_016187   Bridging integrator 2;BIN2;ortholog
2.14    BIRC7      NM_022161                                   protein binding;peptidase inhibitor activity
                               Baculoviral IAP repeat-containing protein 7;BIRC7;ortholog
-2.63   BLP1       NM_078473   TM2 domain-containing protein 2;TM2D2;ortholog
-2.34   BLP2       NM_025141   TM2 domain-containing protein 3;TM2D3;ortholog
-2.26   BMPR2      NM_001204                                   transmembrane receptor protein
                               Bone morphogenetic protein receptor type-2;BMPR2;ortholog kinase activ
-2.78   BNIP2      NM_004330   BCL2/adenovirus E1B 19 kDa protein-interacting protein 2;BNIP2;ortholog
2.64    BNIP3L     NM_004331   BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;BNIP3L;orth
2.06    BOK        NM_032515                                   receptor binding
                               Bcl-2-related ovarian killer protein;BOK;ortholog
-2.08   BOLA1      NM_016074   BolA-like protein 1;BOLA1;ortholog
-2.39   BPHL       NM_004332                                   serine-type peptidase activity
                               Valacyclovir hydrolase;BPHL;ortholog
-3.26   BRAP       NM_006768                                   ubiquitin-protein ligase activity
                               BRCA1-associated protein;BRAP;ortholog
3.58    BRCA1      NM_007294                                   transcription factor activity;transcription facto
                               Breast cancer type 1 susceptibility protein;BRCA1;ortholog
-2.47   BRE        NM_004899   Protein BRE;BRE;ortholog
-2.40   BRI3BP     NM_080626   BRI3-binding protein;BRI3BP;ortholog
2.98    BRIP1      NM_032043                                   DNA helicase activity;nucleic acid binding
                               Fanconi anemia group J protein;BRIP1;ortholog
-2.49   BSCL2      NM_032667   Seipin;BSCL2;ortholog
-2.34   BSDC1      NM_018045   BSD domain-containing protein 1;BSDC1;ortholog
-2.13   BSG        NM_001728   Basigin;BSG;ortholog
2.81    BSPRY      NM_017688                                   ubiquitin-protein ligase activity
                               B box and SPRY domain-containing protein;BSPRY;ortholog
-2.30   BTAF1      NM_003972                                   DNA helicase activity;nucleic
                               TATA-binding protein-associated factor 172;BTAF1;ortholog acid binding
2.80    BTD        NM_000060   Biotinidase;BTD;ortholog       hydrolase activity
2.41    BTF3L4     XM_371577                                  transcription factor activity;transcription facto
                               Transcription factor BTF3 homolog 4;BTF3L4;ortholog
3.16    BTNL2      NM_019602   Butyrophilin-like protein 2;BTNL2;ortholog
5.81    BUB1       NM_004336                                  protein kinase activity
                               Mitotic checkpoint serine/threonine-protein kinase BUB1;BUB1;ortholog
-2.68   BUCS1      NM_052956                                   ACSM1, mitochondrial;ACSM1;ortholog
                               Acyl-coenzyme A synthetaseligase activity
2.71    BZW1       NM_014670                                  nuclease activity;translation factor activity,
                               Basic leucine zipper and W2 domain-containing protein 1;BZW1;orthologn
-2.49   C10ORF129 NM_207321                                    ACSM6, mitochondrial;ACSM6;ortholog
                               Acyl-coenzyme A synthetaseligase activity
2.92    C10ORF140 NM_207371    Protein DLN-1;C10orf140;ortholog
3.18    C10ORF59   NM_018363   Renalase;C10orf59;ortholog
3.93    C10ORF94   NM_130784   Synaptonemal complex central element protein 1;SYCE1;ortholog
-3.18   C11ORF13   NM_003475   Ras association domain-containing protein 7;RASSF7;ortholog
3.00    C11ORF30   NM_020193   Protein EMSY;EMSY;ortholog
-2.47   C11ORF73   NM_016401   Uncharacterized protein C11orf73;C11orf73;ortholog
3.43    C11ORF79,SDH5
                   NM_017841                                  protein binding
                               Protein EMI5 homolog, mitochondrial;C11orf79;ortholog
-1.95   C13ORF17   NM_018185   DCN1-like protein 2;DCUN1D2;ortholog
-2.44   C13ORF31   NM_153218   UPF0124 protein C13orf31;C13orf31;ortholog
2.64    C14ORF11   NM_018453   E2F-associated phosphoprotein;EAPP;ortholog
4.15    C14ORF115 NM_018228    Uncharacterized protein C14orf115;C14orf115;ortholog
2.57    C14ORF162 NM_020181    NM_020181.2 was permanently suppressed because currently there is su
3.94    C14ORF2    NM_004894   6.8 kDa mitochondrial proteolipid;MP68;ortholog
4.05    C14ORF58   NM_017791                                  transmembrane transporter 2;FLVCR2;ortho
                               Feline leukemia virus subgroup C receptor-related protein activity
-2.39   C15ORF24   NM_020154   UPF0480 protein C15orf24;C15orf24;ortholog
-2.19   C17ORF103 NM_152914    Protein GTLF3B;GTLF3B;ortholog
2.15    C17ORF38   XM_375404                                  protein subunit 6;PIK3R6;ortholog
                               Phosphoinositide 3-kinase regulatory binding;kinase regulator activity
-2.08   C17ORF39   NM_024052   Uncharacterized protein C17orf39;C17orf39;ortholog
2.59    C17ORF63   NM_018182   Uncharacterized protein C17orf63;C17orf63;ortholog
-2.46   C19ORF22   NM_138774   R3H domain-containing protein C19orf22;C19orf22;ortholog
-2.75   C19ORF32   NM_138393                                  receptor activity;transmembrane transporter
                               Receptor expression-enhancing protein 6;REEP6;ortholog
2.08    C19ORF77   XM_209196   Transmembrane protein HSPC323;YS019_HUMAN;ortholog
2.46    C1ORF114   NM_021179   Uncharacterized protein C1orf114;C1orf114;ortholog
3.06    C1ORF14    NM_030933   Uncharacterized protein C1orf14;C1orf14;ortholog
4.04    C1ORF159   NM_017891   Uncharacterized protein C1orf159;C1orf159;ortholog
2.42    C1ORF227   XM_086616   UPF0732 protein C1orf227
-3.24   C1ORF50    NM_024097   Uncharacterized protein C1orf50;C1orf50;ortholog
2.42    C1ORF56    NM_017860   Uncharacterized protein C1orf56;C1orf56;ortholog
-2.11   C1ORF57    NM_032324                                  kinase activity
                               Nucleoside-triphosphatase C1orf57;C1orf57;ortholog
2.37    C1ORF66    NM_015997                                  RNA methyltransferase activity;nucleic acid
                               UPF0431 protein C1orf66;C1orf66;ortholog
7.01    C1S        NM_001734                                  serine-type peptidase activity
                               Complement C1s subcomponent light chain;C1S;ortholog
-2.17   C2         NM_000063                                  serine-type
                               Complement C2a fragment;C2;ortholog peptidase activity
3.41    C20ORF13   NM_017714                                  peptidase activity
                               Threonine aspartase subunit beta;TASP1;ortholog
-2.47   C20ORF135 NM_080622    Uncharacterized protein C20orf135;C20orf135;ortholog
-2.24   C20ORF151 NM_080833                                   transcription factor activity;transcription facto
                               Uncharacterized protein C20orf151;C20orf151;ortholog
-2.26   C20ORF161 NM_033421    Sorting nexin-21;SNX21;ortholog
3.38    C20ORF177 NM_022106    Uncharacterized protein C20orf177;C20orf177;ortholog
-2.59   C20ORF19   NM_018474   Uncharacterized protein C20orf19;C20orf19;ortholog
2.89    C20ORF27   NM_017874   UPF0687 protein C20orf27;C20orf27;ortholog
-2.02   C20ORF36   NM_018257                                  methyltransferase activity
                               Protein-L-isoaspartate O-methyltransferase domain-containing protein 2;PC
3.55    C20ORF43   NM_016407   UPF0549 protein C20orf43;C20orf43;ortholog
3.78    C20ORF54   NM_033409                                  G-protein coupled receptor activity
                               Uncharacterized protein C20orf54;C20orf54;ortholog
-2.37   C20ORF79   NM_178483   Uncharacterized protein C20orf79;C20orf79;ortholog
5.64    C21ORF42   NM_058184   Uncharacterized protein C21orf42;C21orf42;ortholog
3.18    C21ORF45   NM_018944   Protein Mis18-alpha;MIS18A;ortholog
-2.67   C21ORF67   NM_058189   Uncharacterized protein C21orf67;C21orf67;ortholog
-1.97   C21ORF81   NM_153750   Uncharacterized protein C21orf81;C21orf81;ortholog
2.80    C22ORF1    NM_001585                                   hydrolase activity
                               Metallophosphoesterase domain-containing protein 1;MPPED1;ortholog
3.74    C22ORF26   NM_018280   Putative uncharacterized protein C22orf26;C22orf26;ortholog
5.21    C22ORF34   NM_198851   Uncharacterized protein C22orf34;C22orf34;ortholog
4.07    C22ORF8    NM_017911   Protein FAM118A;FAM118A;ortholog
3.77    C2CD3      NM_015531   C2 domain-containing protein 3;C2CD3;ortholog
-2.26   C2orf12    BC069763                                    DNA replication protein 1;RBMS1;ortholog
                               RNA-binding motif, single-stranded-interacting origin binding;single-strande
-3.74   C2ORF28    NM_016085   Apoptosis-related protein 3;APR3;ortholog
2.21    C2ORF29    NM_017546   Uncharacterized protein C2orf29;C2orf29;ortholog
-2.23   C2ORF30    NM_015701   XTP3-transactivated gene B protein;C2orf30;ortholog
-2.10   C2ORF79    XM_372919                                   phosphoprotein phosphatase activity;phosph
                               Uncharacterized protein C2orf79;C2orf79;ortholog
4.49    C2ORF81    XM_371503   Uncharacterized protein C2orf81;C2orf81;ortholog
-2.78   C3ORF1     NM_016589   Transmembrane protein C3orf1;C3orf1;ortholog
2.54    C3ORF36    NM_025041   Uncharacterized protein C3orf36;C3orf36;ortholog
-2.15   C3ORF64    NM_173654                                   transferase activity, transferring
                               Uncharacterized glycosyltransferase AER61;AER61;ortholog glycosyl gro
-2.90   C4ORF17    NM_032149   Uncharacterized protein C4orf17;C4orf17;ortholog
3.69    C4ORF21    NM_018392   Uncharacterized protein C4orf21;C4orf21;ortholog
2.36    C5ORF14    NM_024715   Thioredoxin domain-containing protein 15;TXNDC15;ortholog
-2.44   C5ORF45    NM_016175   UPF0544 protein C5orf45;C5orf45;ortholog
-2.97   C5ORF51    NM_175921   UPF0600 protein C5orf51;C5orf51;ortholog
-2.28   C5ORF6     NM_016605   Protein FAM53C;FAM53C;ortholog
-2.55   C6ORF115   XM_371848   Uncharacterized protein C6orf115;C6orf115;ortholog
2.85    C6ORF70    XM_376556   Transmembrane protein C6orf70;C6orf70;ortholog
2.19    C6ORF96    NM_017909   Required for meiotic nuclear division protein 1 homolog;RMND1;ortholog
2.86    C7ORF16    NM_006658   G-substrate;GSBS;ortholog
4.38    C7ORF42    NM_017994   UPF0458 protein C7orf42;C7orf42;ortholog
-1.95   C7ORF62    NM_152706   Uncharacterized protein C7orf62;C7orf62;ortholog
2.92    C9ORF156   NM_016481   Nef-associated protein 1;C9orf156;ortholog
3.54    C9ORF158   NM_031219                                   hydrolase activity
                               Haloacid dehalogenase-like hydrolase domain-containing protein 3;HDHD3
2.92    C9ORF16    NM_024112   UPF0184 protein C9orf16;C9orf16;ortholog
2.47    C9orf165   NM_198573   Uncharacterized protein C9orf165;C9orf165;ortholog
3.00    C9ORF36    NM_015667   Protein FAM75A1;FAM75A1;ortholog
-2.16   C9ORF39    NM_017738   Centlein;CNTLN;ortholog
-2.44   C9ORF4     XM_378078   Uncharacterized protein C9orf4;C9orf4;ortholog
-1.99   C9ORF59    NM_033387   Protein FAM78A;FAM78A;ortholog
-2.44   C9ORF74    NM_030914   Ubiquitin-related modifier 1 homolog;URM1;ortholog
-2.11   C9ORF81    XM_095991   Centrosomal protein of 78 kDa;CEP78;ortholog
-2.19   C9ORF87    NM_018112   Trimeric intracellular cation channel type B;TMEM38B;ortholog
-2.46   CABLES1    NM_138375   CDK5 and ABL1 enzyme substrate 1;CABLES1;ortholog
-2.38   CABP5      NM_019855                                   calcium ion
                               Calcium-binding protein 5;CABP5;orthologbinding;calmodulin binding
-2.53   CACNA1A    NM_000068                                   voltage-gated calcium channel activity;voltag
                               Voltage-dependent P/Q-type calcium channel subunit alpha-1A;CACNA1A
-2.62   CACNA1C    NM_000719                                   voltage-gated calcium channel activity;voltag
                               Voltage-dependent L-type calcium channel subunit alpha-1C;CACNA1C;or
3.75    CACNA1H    NM_021098                                   voltage-gated calcium channel activity;voltag
                               Voltage-dependent T-type calcium channel subunit alpha-1H;CACNA1H;or
-2.07   CACNA1I    NM_021096                                   voltage-gated calcium channel activity;voltag
                               Voltage-dependent T-type calcium channel subunit alpha-1I;CACNA1I;orth
2.69    CACNA2D3   NM_018398                                   voltage-gated delta-3;CACNA2D3;ortholog
                               Voltage-dependent calcium channel subunitcalcium channel activity;voltag
3.04    CACNG6     NM_145814   Voltage-dependent calcium channel gamma-6 subunit;CACNG6;ortholog
2.85    CACNG7     NM_031896                                   voltage-gated calcium channel activity;voltag
                               Voltage-dependent calcium channel gamma-7 subunit;CACNG7;ortholog
3.57    CAMK2G     NM_001222                                   protein kinase activity
                               Calcium/calmodulin-dependent protein kinase type II gamma chain;CAMK
2.70    CAMP       NM_004345                                   protein binding;peptidase inhibitor activity
                               Antibacterial protein LL-37;CAMP;ortholog
3.23    CAPZB      NM_004930                                   structural constituent of
                               F-actin-capping protein subunit beta;CAPZB;ortholog cytoskeleton;actin b
-2.87   CARD11     NM_032415   Caspase recruitment domain-containing protein 11;CARD11;ortholog
2.72    CARD6     NM_032587   Caspase recruitment domain-containing protein 6;CARD6;ortholog
5.61    CARKD     NM_018210   Carbohydrate kinase domain-containing protein;CARKD;ortholog
-2.21   CART      NM_004291   CART(42-89);CARTPT;ortholog
2.57    CASP4     NM_001225                                   cysteine-type peptidase activity
                              Caspase-4 subunit 2;CASP4;ortholog
3.84    CAST      NM_015576   Calpastatin;CAST;ortholog protein binding;cysteine-type endopeptidase
-2.46   CBR1      NM_001757                                    1;CBR1;ortholog
                              Carbonyl reductase [NADPH] oxidoreductase activity
2.71    CBX8      NM_020649                                   nucleic acid binding;chromatin binding
                              Chromobox protein homolog 8;CBX8;ortholog
-2.41   CCDC114   NM_144577   Coiled-coil domain-containing protein 114;CCDC114;ortholog
-2.62   CCDC121   NM_024584   Coiled-coil domain-containing protein 121;CCDC121;ortholog
-2.08   CCDC128   NM_152994   Coiled-coil domain-containing protein 128;CCDC128;ortholog
2.93    CCDC132   NM_024553   Coiled-coil domain-containing protein 132;CCDC132;ortholog
2.88    CCDC151   NM_145045   Coiled-coil domain-containing protein 151;CCDC151;ortholog
-2.00   CCDC6     NM_005436   Coiled-coil domain-containing protein 6;CCDC6;ortholog
-2.20   CCDC60    NM_178499   Coiled-coil domain-containing protein 60;CCDC60;ortholog
2.59    CCDC74A   NM_138770   Coiled-coil domain-containing protein 74A;CCDC74A;ortholog
4.03    CCDC87    NM_018219   Coiled-coil domain-containing protein 87;CCDC87;ortholog
-1.97   CCDC96    NM_153376   Coiled-coil domain-containing protein 96;CCDC96;ortholog
-2.22   CCKAR     NM_000730                                    A;CCKAR;ortholog
                              Cholecystokinin receptor typeG-protein coupled receptor activity
2.11    CCL21     NM_002989                                   chemokine
                              C-C motif chemokine 21;CCL21;ortholog activity
-2.14   CCL22     NM_002990   MDC(7-69);CCL22;ortholog chemokine activity
-2.41   CCL28     NM_019846                                   chemokine
                              C-C motif chemokine 28;CCL28;ortholog activity
3.46    CCNB3     NM_033031                                   protein binding;kinase activator activity;kinas
                              G2/mitotic-specific cyclin-B3;CCNB3;ortholog
2.15    CCNG1     NM_004060   Cyclin-G1;CCNG1;ortholog protein binding;kinase activator activity;kinas
-2.76   CCNI      NM_006835   Cyclin-I;CCNI;ortholog          protein binding;kinase activator activity;kinas
2.52    CCNJ      NM_019084   Cyclin-J;CCNJ;ortholog          protein binding;kinase activator activity;kinas
-2.53   CCNT1     NM_001240   Cyclin-T1;CCNT1;ortholog        transcription factor activity;protein binding;ki
2.31    CD1A      NM_001763                                   receptor activity
                              T-cell surface glycoprotein CD1a;CD1A;ortholog
-2.00   CD24      NM_013230   Signal transducer CD24;CD24;ortholog
-2.95   CD5L      NM_005894   CD5 antigen-like;CD5L;ortholog  receptor activity
-2.27   CD68      NM_001251   Macrosialin;CD68;ortholog
-2.32   CD79A     NM_001783                                   receptor activity
                              B-cell antigen receptor complex-associated protein alpha-chain;CD79A;ort
2.30    CD84      NM_003874                                   receptor
                              SLAM family member 5;CD84;orthologactivity;receptor binding
2.20    CDC10     NM_001788   Septin-7;SEPT7;ortholog         GTPase activity;structural constituent of cyto
-3.00   CDC23     NM_004661                                   ubiquitin-protein ligase activity
                              Cell division cycle protein 23 homolog;CDC23;ortholog
-3.27   CDC25B    NM_004358                                   phosphoprotein phosphatase activity;phosph
                              M-phase inducer phosphatase 2;CDC25B;ortholog
-2.32   CDC25C    NM_001790                                   phosphoprotein phosphatase activity;phosph
                              M-phase inducer phosphatase 3;CDC25C;ortholog
-3.19   CDC27     NM_001256   Cell division cycle protein 27 homolog;CDC27;ortholog
-2.50   CDC37     NM_007065                                   protein binding;kinase activator activity;kinas
                              Hsp90 co-chaperone Cdc37;CDC37;ortholog
-2.80   CDC42     NM_001791                                    homolog;CDC42;ortholog
                              Cell division control protein 42GTPase activity;protein binding
2.54    CDC45L    NM_003504                                   DNA replication origin binding
                              CDC45-related protein;CDC45L;ortholog
2.53    CDCA4     NM_017955                                    protein 4;CDCA4;ortholog
                              Cell division cycle-associated transcription factor activity;transcription facto
-2.24   CDCA5     NM_080668   Sororin;CDCA5;ortholog
2.51    CDH19     NM_021153   Cadherin-19;CDH19;ortholog calcium ion binding
-2.18   CDH2      NM_001792   Cadherin-2;CDH2;ortholog        calcium ion binding
2.73    CDH23     NM_022124   Cadherin-23;CDH23;ortholog calcium ion binding
-2.08   CDK11A    NM_024011                                   protein kinase activity
                              Cell division cycle 2-like protein kinase 6;CDC2L2;ortholog
2.18    CDK8      NM_001260                                   protein kinase
                              Cell division protein kinase 8;CDK8;ortholog activity
-3.23   CDKN2A    NM_000077   Cyclin-dependent kinase inhibitor 2A, isoform 4;CDKN2A;ortholog
-2.73   CEBPE     NM_001805                                   transcription factor activity;transcription facto
                              CCAAT/enhancer-binding protein epsilon;CEBPE;ortholog
2.78    CEND1     NM_016564   Cell cycle exit and neuronal differentiation protein 1;CEND1;ortholog
2.37    CENTA2    NM_018404                                   nucleic
                              Centaurin-alpha-2;CENTA2;ortholog acid binding;protein binding;small GT
-2.28   CES2      NM_003869   Carboxylesterase 2;CES2;orthologhydrolase activity, acting on ester bonds
-3.63   CES4      NM_016280                                   hydrolase activity, acting on ester bonds
                              Inactive carboxylesterase 4;CES4;ortholog
3.18    CFB       NM_001710                                   serine-type peptidase activity
                              Complement factor B Bb fragment;CFB;ortholog
2.96    CFL1      NM_005507   Cofilin-1;CFL1;ortholog         structural constituent of cytoskeleton;actin b
-2.13   CGB1      NM_033377                                   hormone activity
                              Choriogonadotropin subunit beta variant 1;CGB1;ortholog
3.63    CHCHD3    NM_017812   Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondria
2.72    CHEK1     NM_001274                                   protein kinase activity
                              Serine/threonine-protein kinase Chk1;CHEK1;ortholog
6.75    CHKA      NM_001277                                   kinase
                              Choline kinase alpha;CHKA;ortholog activity
4.20    CHRAC1    NM_017444                                   DNA-directed DNA polymerase
                              Chromatin accessibility complex protein 1;CHRAC1;ortholog activity;trans
-2.36   CHRDL1    NM_145234                                   receptor binding
                              Chordin-like protein 1;CHRDL1;ortholog
-2.41   CHST11    NM_018413                                    11;CHST11;ortholog
                              Carbohydrate sulfotransferasetransferase activity
2.56    CIAO1     NM_004804   Protein CIAO1;CIAO1;ortholog
-2.35   CIAPIN1   NM_020313   Anamorsin;CIAPIN1;ortholog
2.24    CIB1      NM_006384                                   kinase activity;phosphoprotein phosphatase
                              Calcium and integrin-binding protein 1;CIB1;ortholog
-3.69   CIDEC     NM_022094   Cell death activator CIDE-3;CIDEC;ortholog
-2.25   CIG5      NM_080657   Radical S-adenosyl methionine domain-containing protein 2;RSAD2;orthol
-2.03   CLCF1     NM_013246                                   hematopoietin/interferon-class (D200-domain
                              Cardiotrophin-like cytokine factor 1;CLCF1;ortholog
-3.05   CLCN5     NM_000084                                   anion channel
                              Chloride channel protein 5;CLCN5;ortholog activity
2.49    CLDN1     NM_021101   Claudin-1;CLDN1;ortholog
2.68    CLDN10    NM_006984   Claudin-10;CLDN10;ortholog
2.39    CLDN12    NM_012129   Claudin-12;CLDN12;ortholog
2.62    CLDN17    NM_012131   Claudin-17;CLDN17;ortholog
2.96    CLECSF2   NM_005127                                   member B;CLEC2B;ortholog
                              C-type lectin domain family 2 receptor activity;receptor binding
-3.17   CLN3      NM_000086   Battenin;CLN3;ortholog
-3.82   CLPP      NM_006012                                   serine-type peptidase activity
                              Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial;C
11.10   CMPK1     NM_016308   UMP-CMP kinase;CMPK1;ortholog   nucleotide kinase activity
-2.32   CNGA1     NM_000087                                   receptor activity;voltage-gated potassium ch
                              cGMP-gated cation channel alpha-1;CNGA1;ortholog
-2.15   CNNM2     NM_017649   Metal transporter CNNM2;CNNM2;ortholog
-2.80   CNTN5     NM_014361   Contactin-5;CNTN5;ortholog phosphoprotein phosphatase activity;phosph
2.98    COL17A1   NM_000494                                   extracellular matrix structural constituent
                              97 kDa linear IgA disease antigen;COL17A1;ortholog
-2.89   COL1A1    NM_000088                                   extracellular
                              Collagen alpha-1(I) chain;COL1A1;orthologmatrix structural constituent
-2.17   COL4A1    NM_001845   Collagen alpha-1(IV) chain;COL4A1;ortholog
-2.55   COL4A2    NM_001846   Canstatin;COL4A2;ortholog extracellular matrix structural constituent
-2.29   COL4A3    NM_000091   Tumstatin;COL4A3;ortholog
-2.09   COL4A5    NM_000495   Collagen alpha-5(IV) chain;COL4A5;ortholog
-2.75   COL4A6    NM_001847                                   extracellular matrix structural constituent
                              Collagen alpha-6(IV) chain;COL4A6;ortholog
-3.03   COL6A1    NM_001848                                   extracellular matrix structural constituent
                              Collagen alpha-1(VI) chain;COL6A1;ortholog
-2.19   COL6A2    NM_001849                                   extracellular matrix structural constituent
                              Collagen alpha-2(VI) chain;COL6A2;ortholog
2.22    COL9A2    NM_001852                                   extracellular matrix structural constituent
                              Collagen alpha-2(IX) chain;COL9A2;ortholog
-2.88   COLQ      NM_005677                                   extracellular matrix structural
                              Acetylcholinesterase collagenic tail peptide;COLQ;ortholog constituent
7.48    COMT      NM_000754                                   methyltransferase
                              Catechol O-methyltransferase;COMT;ortholog activity
2.35    COPS4     NM_016129   COP9 signalosome complex subunit 4;COPS4;ortholog
4.05    COQ4      NM_016035   Ubiquinone biosynthesis protein COQ4 homolog;COQ4;ortholog
-2.48   CORO1B    NM_020441   Coronin-1B;CORO1B;orthologstructural constituent of cytoskeleton;actin b
-2.19   CORO7     NM_024535   Coronin-7;CORO7;ortholog structural constituent of cytoskeleton;actin b
-2.12   CPA1      NM_001868                                   metallopeptidase activity
                              Carboxypeptidase A1;CPA1;ortholog
3.54    CPB2      NM_001872                                   metallopeptidase activity
                              Carboxypeptidase B2;CPB2;ortholog
-3.26   CPN1      NM_001308                                    chain;CPN1;ortholog
                              Carboxypeptidase N catalytic metallopeptidase activity
-2.36   CPN2      J05158                                      receptor activity
                              Carboxypeptidase N subunit 2;CPN2;ortholog
-2.72   CPSF3     NM_016207                                    specificity factor activity;poly(A) RNA bindin
                              Cleavage and polyadenylationendoribonuclease subunit 3;CPSF3;ortholog
2.48    CPT1A     NM_001876                                   acetyltransferase activity
                              Carnitine O-palmitoyltransferase 1, liver isoform;CPT1A;ortholog
-2.52   CRAT      NM_000755                                   acetyltransferase
                              Carnitine O-acetyltransferase;CRAT;ortholog activity
1.99    CRB1      NM_012076   Crumbs homolog 1;CRB1;ortholog
5.31    CREG       NM_003851 Protein CREG1;CREG1;ortholog
3.18    CRI1       NM_014335 EP300-interacting inhibitor of differentiation 1;EID1;ortholog
2.02    CRIP1                                                structural
                   NM_001311 Cysteine-rich protein 1;CRIP1;ortholog constituent of cytoskeleton
-3.10   CRK        NM_005206 Proto-oncogene C-crk;CRK;ortholog
2.47    CRTAC1                                               calcium ion binding;calmodulin binding;calciu
                   NM_018058 Cartilage acidic protein 1;CRTAC1;ortholog
2.15    CRYAA      NM_000394                                 structural molecule activity
                              Alpha-crystallin A chain, short form;CRYAA;ortholog
-3.33   CRYGA                                                structural
                   NM_014617 Gamma-crystallin A;CRYGA;ortholog molecule activity
2.44    CRYGD                                                structural
                   NM_006891 Gamma-crystallin D;CRYGD;ortholog molecule activity
2.68    CRYZL1     NM_005111                                 oxidoreductase activity
                              Quinone oxidoreductase-like protein 1;CRYZL1;ortholog
-2.51   CSEN       NM_013434 Calsenilin;KCNIP3;ortholog calcium ion binding
3.02    CSGLCA-T                                             transferase activity, transferring
                   NM_019015 Chondroitin sulfate glucuronyltransferase;CSGLCAT;ortholog glycosyl gro
3.26    CSMD2      NM_052896  CUB and sushi domain-containing protein 2;CSMD2;ortholog
3.96    CSRP3                                                structural constituent
                   NM_003476 Cysteine and glycine-rich protein 3;CSRP3;orthologof cytoskeleton
-2.21   CST7       NM_003650 Cystatin-F;CST7;ortholog        protein binding;cysteine-type endopeptidase
2.51    CSTP1      NM_018340 Uncharacterized metallophosphoesterase CSTP1;CSTP1;ortholog
6.09    CTCF                                                 transcription factor
                   NM_006565 Transcriptional repressor CTCF;CTCF;ortholog activity;transcription facto
-2.28   CTNNA1     NM_001903 Catenin alpha-1;CTNNA1;ortholog structural constituent of cytoskeleton;actin b
-3.56   CTNND1     NM_001331 Catenin delta-1;CTNND1;ortholog structural constituent of cytoskeleton;interm
-2.73   CTPS       NM_001905  CTP synthase 1;CTPS;ortholog   ligase activity
4.30    CTPS2      NM_019857  CTP synthase 2;CTPS2;ortholog  ligase activity
-2.80   CTSF       NM_003793 Cathepsin F;CTSF;ortholog cysteine-type peptidase activity
3.25    CTTN                                                 structural
                   NM_005231 Src substrate cortactin;CTTN;ortholog constituent of cytoskeleton;actin b
7.26    CUL9       NM_015089  p53-associated parkin-like cytoplasmic protein;PARC;ortholog
-2.28   CUZD1                                                oxidoreductase activity;serine-type peptidas
                   NM_022034 CUB and zona pellucida-like domain-containing protein 1;CUZD1;ortholog
2.23    CXORF27    XM_048235 Huntingtin-interacting protein M;CXorf27;ortholog
-2.76   CXXC4      NM_025212 CXXC-type zinc finger protein 4;CXXC4;ortholog
-2.31   CYFIP1                                               protein binding;small GTPase
                   NM_014608 Cytoplasmic FMR1-interacting protein 1;CYFIP1;ortholog regulator activ
-2.40   CYLD                                                 structural constituent of ribosome;nucleic ac
                   NM_015247 Probable ubiquitin carboxyl-terminal hydrolase CYLD;CYLD;ortholog
2.18    CYP11B2    NM_000498                                 oxidoreductase activity
                              Cytochrome P450 11B2, mitochondrial;CYP11B2;ortholog
3.92    CYP21A2    NM_000500                                 oxidoreductase activity
                              Cytochrome P450 21;CYP21A2;ortholog
2.04    CYP27A1                                              oxidoreductase activity
                   NM_000784 Cytochrome P450 27, mitochondrial;CYP27A1;ortholog
-2.85   CYP27B1                                              oxidoreductase activity
                   NM_000785 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;CYP27B1;ortholo
3.44    CYP2A6     NM_000762                                 oxidoreductase activity
                              Cytochrome P450 2A6;CYP2A6;ortholog
2.76    CYT19                                                methyltransferase activity
                   NM_020682 Arsenite methyltransferase;AS3MT;ortholog
3.33               NM_021006 LD78-beta(5-70);CCL3L3;ortholog
        D17S1718,SCYA3L1                                     chemokine activity
-2.37   DAB2       NM_001343                                 receptor
                              Disabled homolog 2;DAB2;ortholog binding
2.65    DAF        NM_000574  Complement decay-accelerating factor;CD55;ortholog
7.08    DALRD3                                               aminoacyl-tRNA ligase activity
                   NM_018114 DALR anticodon-binding domain-containing protein 3;DALRD3;ortholog
2.76    DAP13                                                oxidoreductase activity
                   NM_018838 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;NDUF
2.03    DAZ4       NM_020420                                 RNA binding
                              Deleted in azoospermia protein 4;DAZ4;ortholog
2.16    DAZAP1                                               RNA binding
                   NM_018959 DAZ-associated protein 1;DAZAP1;ortholog
3.00    DAZAP2     NM_014764 DAZ-associated protein 2;DAZAP2;ortholog
2.49    DBX2                  Homeobox protein DBX2;DBX2;ortholog factor activity;transcription facto
                   NM_001004329                              transcription
-2.87   DCHS1      NM_003737 Protocadherin-16;DCHS1;ortholog calcium ion binding
6.10    DCLK2                                                protein kinase activity;structural constituent
                   NM_152619 Serine/threonine-protein kinase DCLK2;DCLK2;ortholog
-2.82   DCLRE1B    NM_022836  DNA cross-link repair 1B protein;DCLRE1B;ortholog
2.11    DCPS                                                 hydrolase activity
                   NM_014026 Scavenger mRNA-decapping enzyme DcpS;DCPS;ortholog
2.31    DCTN5                                                microtubule motor activity;structural constitu
                   NM_032486 Dynactin subunit 5;DCTN5;ortholog
3.33    DDA3       NM_032636 Proline/serine-rich coiled-coil protein 1;PSRC1;ortholog
-4.05   DDC                                                  carboxy-lyase activity
                   NM_000790 Aromatic-L-amino-acid decarboxylase;DDC;ortholog
3.29    DDEF2                                                nucleic acid factor 2;DDEF2;ortholog
                   NM_003887 Development and differentiation-enhancing binding;protein binding;small GT
3.14    DDX20                                                RNA helicase activity;translation
                   NM_007204 Probable ATP-dependent RNA helicase DDX20;DDX20;orthologfactor activ
4.68    DDX25       NM_013264                                   DDX25;DDX25;ortholog
                                ATP-dependent RNA helicaseRNA helicase activity;nucleic acid binding
-2.82   DDX26       NM_012141                                  RNA helicase
                                Integrator complex subunit 6;INTS6;ortholog activity;nucleic acid binding
2.52    DDX31       NM_022779                                  RNA helicase activity;nucleic acid
                                Probable ATP-dependent RNA helicase DDX31;DDX31;ortholog binding
2.15    DDX3X       NM_001356                                   DDX3X;DDX3X;ortholog
                                ATP-dependent RNA helicaseRNA helicase activity;nucleic acid binding
6.41    DDX6        NM_004397                                  RNA helicase activity;nucleic acid binding
                                Probable ATP-dependent RNA helicase DDX6;DDX6;ortholog
2.47    DDX60       NM_017631                                  DNA helicase activity;hydrolase activity;nucl
                                Probable ATP-dependent RNA helicase DDX60;DDX60;ortholog
-2.67   DECR2       NM_020664                                  reductase;DECR2;ortholog
                                Peroxisomal 2,4-dienoyl-CoA oxidoreductase activity
2.74    DEF8        NM_207514   Differentially expressed in FDCP 8 homolog;DEF8;ortholog
-2.82   DEPDC1B     NM_018369                                  nucleic acid binding
                                DEP domain-containing protein 1B;DEPDC1B;ortholog
2.41    DEPDC2      NM_024870                                  receptor activity;protein binding;small 2 prote
                                Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger GTPas
2.37    DERA        NM_015954                                  lyase activity
                                Putative deoxyribose-phosphate aldolase;DERA;ortholog
3.89    DES         NM_001927   Desmin;DES;ortholog            structural constituent of cytoskeleton
2.52    DGKD        NM_003648                                  kinase activity
                                Diacylglycerol kinase delta;DGKD;ortholog
-2.78   DHCR7       NM_001360                                  oxidoreductase activity;receptor activity
                                7-dehydrocholesterol reductase;DHCR7;ortholog
-3.80   DHFRP1      NM_000791                                  oxidoreductase activity
                                Dihydrofolate reductase;DHFRP1;ortholog
-2.36   DHH         NM_021044                                  peptidase activity;receptor binding
                                Desert hedgehog protein C-product;DHH;ortholog
2.65    DHRS1       NM_138452                                  oxidoreductase activity
                                Dehydrogenase/reductase SDR family member 1;DHRS1;ortholog
-2.33   DIRC2       NM_032839                                  transmembrane transporter activity
                                Disrupted in renal carcinoma protein 2;DIRC2;ortholog
-2.38   DISC1       NM_018662   Disrupted in schizophrenia 1 protein;DISC1;ortholog
-2.40   DKFZP564I1171L117555
                    A           cDNA DKFZp564I1171
4.44    DKFZP586K1520
                    XM_376189   This record was removed as a result of standard genome annotation proce
4.05    DLG4        NM_001365   Disks large homolog 4;DLG4;ortholog
-3.11   DLST        NM_001933                                  acyltransferase activity
                                Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutara
-2.62   DLX6        XM_376652                                  transcription
                                Homeobox protein DLX-6;DLX6;ortholog factor activity;transcription facto
3.71    DMC1        NM_007068                                   DMC1/LIM15 homolog;DMC1;ortholog
                                Meiotic recombination protein hydrolase activity;DNA strand annealing acti
-2.64   DMGDH       NM_013391                                  oxidoreductase activity
                                Dimethylglycine dehydrogenase, mitochondrial;DMGDH;ortholog
-2.34   DMKN        NM_033317   Dermokine;DMKN;ortholog
3.98    DMRT3       NM_021240                                    transcription factor
                                Doublesex- and mab-3-relatednucleic acid binding 3;DMRT3;ortholog
2.49    DMRTA2      XM_027162                                    transcription factor
                                Doublesex- and mab-3-relatednucleic acid binding A2;DMRTA2;ortholog
4.01    DMTF1       NM_021145                                  transcription factor activity;transcription facto
                                Cyclin-D-binding Myb-like transcription factor 1;DMTF1;ortholog
-2.25   DNAH17      NM_173628                                  microtubule motor activity;hydrolase activity;
                                Dynein heavy chain 17, axonemal;DNAH17;ortholog
2.83    DNAH7       NM_018897                                  microtubule motor activity;hydrolase activity;
                                Dynein heavy chain 7, axonemal;DNAH7;ortholog
2.53    DNAJB12     NM_017626   DnaJ homolog subfamily B member 12;DNAJB12;ortholog
3.85    DND1        NM_194249                                  RNA binding
                                Dead end protein homolog 1;DND1;ortholog
3.07    DNM3        NM_015569   Dynamin-3;DNM3;ortholog GTPase activity;structural constituent of cyto
2.21    DNMT2       NM_004412                                  DNA-methyltransferase activity;nucleic acid
                                tRNA (cytosine-5-)-methyltransferase;TRDMT1;ortholog
-2.49   DNMT3A      NM_022552                                  DNA-methyltransferase activity;nucleic acid
                                DNA (cytosine-5)-methyltransferase 3A;DNMT3A;ortholog
4.44    DNTT        NM_004088                                  DNA-directed DNA
                                DNA nucleotidylexotransferase;DNTT;ortholog polymerase activity;nucle
5.19    DOCK10      XM_371595                                  protein binding;small GTPase regulator activ
                                Dedicator of cytokinesis protein 10;DOCK10;ortholog
-2.18   DOCK9       NM_015296                                  protein binding;small
                                Dedicator of cytokinesis protein 9;DOCK9;ortholog GTPase regulator activ
-2.25   DOLPP1      NM_020438                                  hydrolase activity
                                Dolichyldiphosphatase 1;DOLPP1;ortholog
-2.78   DPEP1       NM_004413   Dipeptidase 1;DPEP1;ortholog   metallopeptidase activity
-3.05   DPYS        NM_001385                                  hydrolase activity
                                Dihydropyrimidinase;DPYS;ortholog
3.34    DUOX2       NM_014080   Dual oxidase 2;DUOX2;ortholog  oxidoreductase activity
-2.67   DUSP15      NM_080611                                  phosphoprotein phosphatase
                                Dual specificity protein phosphatase 15;DUSP15;ortholog activity;phosph
-2.29   DUSP28      XM_209509                                  phosphoprotein phosphatase activity;phosph
                                Dual specificity phosphatase 28;DUSP28;ortholog
-2.05   DUSP3       NM_004090                                  phosphoprotein phosphatase activity;phosph
                                Dual specificity protein phosphatase 3;DUSP3;ortholog
-3.60   DUSP9       NM_001395                                  phosphoprotein phosphatase activity;phosph
                                Dual specificity protein phosphatase 9;DUSP9;ortholog
-2.72   DVL2        NM_004422                                  receptor binding;enzyme regulator activity
                                Segment polarity protein dishevelled homolog DVL-2;DVL2;ortholog
-3.21   DVL3        NM_004423                                  receptor binding;enzyme regulator activity
                                Segment polarity protein dishevelled homolog DVL-3;DVL3;ortholog
-2.51   DYDC2       NM_032372   DPY30 domain-containing protein 2;DYDC2;ortholog
2.00    DYRK1A      NM_001396                                  non-membrane spanning protein tyrosine kin
                                Dual specificity tyrosine-phosphorylation-regulated kinase 1A;DYRK1A;ort
-2.56   E2F2       NM_004091                                   transcription
                               Transcription factor E2F2;E2F2;ortholog factor activity;transcription facto
2.25    ECM2       NM_001393   Extracellular matrix protein 2;ECM2;ortholog
2.43    EDEM1      XM_376201                                   hydrolase activity
                               ER degradation-enhancing alpha-mannosidase-like 1;EDEM1;ortholog
6.12    EDEM2      NM_018217                                   hydrolase activity
                               ER degradation-enhancing alpha-mannosidase-like 2;EDEM2;ortholog
2.68    EDN1       NM_001955   Big endothelin-1;EDN1;ortholog  hormone activity
-2.13   EED        NM_003797                                   transcription factor activity;transcription facto
                               Polycomb protein EED;EED;ortholog
-2.17   EFNB1      NM_004429   Ephrin-B1;EFNB1;ortholog receptor binding
-2.35   EGFL8      NM_030652                                   calcium ion binding
                               EGF-like domain-containing protein 8;EGFL8;ortholog
-2.41   EGR2       NM_000399                                     2;EGR2;ortholog
                               Early growth response proteintranscription factor activity;transcription facto
-2.54   EHD2       NM_014601                                    2;EHD2;ortholog
                               EH domain-containing protein calcium ion binding;protein binding;small GT
7.01    EHMT2      NM_006709   Histone-lysine N-methyltransferase, H3 lysine-9 specific 3;EHMT2;ortholo
3.27    EIF2C2     NM_012154                                   translation 2;EIF2C2;ortholog
                               Eukaryotic translation initiation factor 2Cfactor activity, nucleic acid bindin
2.62    EIF4G3     NM_003760                                   translation factor 3;EIF4G3;ortholog
                               Eukaryotic translation initiation factor 4 gammaactivity, nucleic acid bindin
-2.04   EKI1       NM_018638                                   kinase activity
                               Ethanolamine kinase 1;ETNK1;ortholog
-2.77   ELAC2      NM_018127                                   hydrolase activity
                               Zinc phosphodiesterase ELAC protein 2;ELAC2;ortholog
2.14    ELAVL2     NM_004432                                   RNA binding
                               ELAV-like protein 2;ELAVL2;ortholog
-3.01   ELAVL4     NM_021952                                   RNA binding
                               ELAV-like protein 4;ELAVL4;ortholog
-2.51   ELF4       NM_001421                                   transcription factor activity;receptor binding;t
                               ETS-related transcription factor Elf-4;ELF4;ortholog
-2.21   ELMO1      NM_014800                                   receptor binding
                               Engulfment and cell motility protein 1;ELMO1;ortholog
3.08    ELMOD3     NM_032213                                   receptor binding
                               ELMO domain-containing protein 3;ELMOD3;ortholog
-2.77   ELOVL3     NM_152310                                   acyltransferase activity
                               Elongation of very long chain fatty acids protein 3;ELOVL3;ortholog
-2.84   ELYS       NM_015446                                   transcription factor activity;transcription facto
                               AT-hook-containing transcription factor 1;AHCTF1;ortholog
-2.48   EML3       NM_153265   Echinoderm microtubule-associated protein-like 3;EML3;ortholog
-2.19   ENGASE     NM_022759                                   hydrolase activity;deaminase activity
                               Cytosolic endo-beta-N-acetylglucosaminidase;ENASE_HUMAN;ortholog
3.27    ENOSF1     NM_017512                                   racemase and epimerase activity
                               Mitochondrial enolase superfamily member 1;ENOSF1;ortholog
3.84    ENPP1      NM_006208                                   pyrophosphatase
                               Nucleotide pyrophosphatase;ENPP1;ortholog activity;nucleotide phosph
-2.99   ENPP5      NM_021572                                   pyrophosphatase activity;nucleotide phosph
                               Ectonucleotide pyrophosphatase/phosphodiesterase family member 5;EN
-2.41   EPC1       NM_025209                                   nucleic acid binding;chromatin binding
                               Enhancer of polycomb homolog 1;EPC1;ortholog
-2.26   EPS15      NM_001981                                   calcium ion binding;protein binding;small GT
                               Epidermal growth factor receptor substrate 15;EPS15;ortholog
-2.56   ERCC1      NM_001983                                   endodeoxyribonuclease
                               DNA excision repair protein ERCC-1;ERCC1;ortholog activity;nucleic acid
-2.19   ERCC4      NM_005236                                   endodeoxyribonuclease activity;nucleic acid
                               DNA repair endonuclease XPF;ERCC4;ortholog
2.92    ERCC5      NM_000123                                   exodeoxyribonuclease activity;endodeoxyrib
                               DNA repair protein complementing XP-G cells;ERCC5;ortholog
-2.20   ERO1L      NM_014584                                   oxidoreductase activity
                               ERO1-like protein alpha;ERO1L;ortholog
3.08    ERO1LB     NM_019891                                   oxidoreductase activity
                               ERO1-like protein beta;ERO1LB;ortholog
6.75    ERP70      NM_004911                                   protein disulfide
                               Protein disulfide-isomerase A4;PDIA4;orthologisomerase activity
-2.46   ESR1       NM_000125   Estrogen receptor;ESR1;ortholog ligand-dependent nuclear receptor activity;tra
3.67    ETAA16     NM_019002   Ewing's tumor-associated antigen 1;ETAA1;ortholog
-1.97   ETFDH      NM_004453                                   oxidoreductase activity
                               Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial;ET
3.06    EXOSC3     NM_016042                                   exoribonuclease activity;nucleic acid binding
                               Exosome complex exonuclease RRP40;EXOSC3;ortholog
2.30    EXOSC7     NM_015004                                   exoribonuclease activity;nucleic acid binding
                               Exosome complex exonuclease RRP42;EXOSC7;ortholog
3.04    EXT2       NM_000401   Exostosin-2;EXT2;ortholog transferase activity, transferring glycosyl gro
-3.58   EXTL2      NM_001439                                   transferase activity, transferring glycosyl gro
                               Processed exostosin-like 2;EXTL2;ortholog
2.24    EYA1       NM_000503                                   phosphatase activity;phosphatase activity
                               Eyes absent homolog 1;EYA1;ortholog
-2.00   EYA3       NM_001990                                   phosphatase activity;phosphatase activity
                               Eyes absent homolog 3;EYA3;ortholog
3.88    EYA4       NM_004100                                   phosphatase activity;phosphatase activity
                               Eyes absent homolog 4;EYA4;ortholog
-2.76   FAAH       NM_001441                                   transferase activity;hydrolase activity;ligase
                               Fatty-acid amide hydrolase 1;FAAH;ortholog
3.64    FABP2      NM_000134                                   lipid binding
                               Fatty acid-binding protein, intestinal;FABP2;ortholog
-2.85   FAHD2A     NM_016044                                   hydrolase activity
                               Fumarylacetoacetate hydrolase domain-containing protein 2A;FAHD2A;or
-2.74   FALZ       NM_004459                                   acetyltransferase activity;nucleic
                               Nucleosome-remodeling factor subunit BPTF;BPTF;ortholog acid bindin
-2.25   FAM10A6    XM_051271   This RefSeq was permanently suppressed because it is now thought that
2.46    FAM134B    NM_019000   Protein FAM134B;FAM134B;ortholog
2.53    FAM160A2   NM_032127   UPF0518 protein FAM160A2;FAM160A2;ortholog
3.63    FAM164B    XM_087800                                   transcription factor
                               UPF0418 protein FAM164B;FAM164B;ortholog activity;transcription facto
-2.35   FAM18B     NM_016078   Protein FAM18B;FAM18B;ortholog
3.91    FAM21B     XM_290482   Protein FAM21B;FAM21B;ortholog
2.94    FAM45B     NM_018472   This RefSeq was permanently suppressed because it is now thought that
-2.19   FAM46A     NM_017633   Protein FAM46A;FAM46A;ortholog
-2.59   FAM49A     NM_030797   Protein FAM49A;FAM49A;ortholog
2.64    FAM64A     NM_019013   Protein FAM64A;FAM64A;ortholog
-3.58   FAM69B     NM_152421   Protein FAM69B;FAM69B;ortholog
2.47    FAM74A4    NM_207507   Protein FAM74A4;FAM74A4;ortholog
-2.39   FAM83D     NM_030919   Protein FAM83D;FAM83D;ortholog
-2.31   FAM86B1    NM_032916   Protein FAM86B1;FAM86B1;ortholog
2.83    FAM8A1     NM_016255   Protein FAM8A1;FAM8A1;ortholog
-2.25   FAM90A1    NM_018088   Protein FAM90A1;FAM90A1;ortholog
-3.18   FANCI      NM_018193   Fanconi anemia group I protein;FANCI;ortholog
2.64    FANCL      NM_018062                                   ubiquitin-protein ligase
                               E3 ubiquitin-protein ligase FANCL;FANCL;ortholog activity
3.48    FARSLA     NM_004461                                   aminoacyl-tRNA ligase activity
                               Phenylalanyl-tRNA synthetase alpha chain;FARSA;ortholog
3.68    FASN       NM_004104                                   oxidoreductase activity;methyltransferase ac
                               Oleoyl-[acyl-carrier-protein] hydrolase;FASN;ortholog
3.31    FBLN1      NM_001996   Fibulin-1;FBLN1;ortholog        extracellular matrix structural constituent;ca
-3.23   FBN3       NM_032447   Fibrillin-3;FBN3;ortholog       extracellular matrix structural constituent;ca
2.89    FBP2       NM_003837                                   isozyme 2;FBP2;ortholog
                               Fructose-1,6-bisphosphatase carbohydrate phosphatase activity;carbohyd
-2.13   FBS1       NM_022452   Probable fibrosin-1 long transcript protein;FBRS;ortholog
-2.29   FBXL10     NM_032590   JmjC domain-containing histone demethylation protein 1B;FBXL10;ortholo
3.97    FBXL19     XM_375337   F-box/LRR-repeat protein 19;FBXL19;ortholog
-2.62   FBXL5      NM_012161   F-box/LRR-repeat protein 5;FBXL5;ortholog
3.66    FBXO11     NM_012167                                   ubiquitin-protein ligase activity
                               F-box only protein 11;FBXO11;ortholog
4.43    FBXO2      NM_012168   F-box only protein 2;FBXO2;ortholog
-2.08   FBXO23     NM_130465   Tetraspanin-17;TSPAN17;ortholog receptor binding
-2.00   FBXO3      NM_012175                                   ligase
                               F-box only protein 3;FBXO3;orthologactivity
3.56    FBXO40     NM_016298   F-box only protein 40;FBXO40;ortholog
-2.41   FBXO6      NM_018438   F-box only protein 6;FBXO6;ortholog
-2.41   FBXW9      NM_032301   F-box/WD repeat-containing protein 9;FBXW9;ortholog
-2.86   FCRLA      NM_032738                                   receptor activity
                               Fc receptor-like A;FCRLA;ortholog
-2.28   FEM1A      NM_018708   Protein fem-1 homolog A;FEM1A;ortholog
3.94    FEZF1      XM_371948                                   transcription factor
                               Fez family zinc finger protein 1;FEZF1;ortholog activity;transcription facto
3.46    FGD6       XM_370702                                   protein binding;small 6;FGD6;ortholog
                               FYVE, RhoGEF and PH domain-containing protein GTPase regulator activ
-2.52   FGFR1      NM_000604                                   receptor 1;FGFR1;ortholog
                               Basic fibroblast growth factor transmembrane receptor protein kinase activ
7.74    FGFR1OP    NM_007045   FGFR1 oncogene partner;FGFR1OP;ortholog
-2.17   FGFRL1     NM_021923                                   transmembrane receptor protein kinase activ
                               Fibroblast growth factor receptor-like 1;FGFRL1;ortholog
-2.05   FGIF       NM_017704   Ankyrin repeat domain-containing protein 49;ANKRD49;ortholog
-2.29   FIGN       NM_018086   Fidgetin;FIGN;ortholog          hydrolase activity
-2.25   FIP1L1     NM_030917   Pre-mRNA 3'-end-processing factor FIP1;FIP1L1;ortholog
-2.63   FKBP11     NM_016594                                   isomerase activity;calcium ion binding
                               FK506-binding protein 11;FKBP11;ortholog
-2.89   FKSG43     NM_032033   Putative FERM domain-containing protein FKSG43;FKS43_HUMAN;ortho
2.43    FLJ10246   NM_018038   This record was removed by RefSeq staff.
3.72    FLJ11292   NM_018382   NM_018382.1 was permanently suppressed because it appears to represe
-2.13   FLJ14959   XM_371139   This record was removed as a result of standard genome annotation proce
2.32    FLJ40092   NM_207494   This record was removed by RefSeq staff.
-2.28   FLJ40852   NM_173677   NM_173677.1 was permanently suppressed because currently there is su
-2.34   FLJ41200   XM_379623   uncharacterized LOC401492 (FLJ41200), non-coding RNA
3.71    FLJ41327   NM_207485   NM_207485.1 was permanently suppressed because currently there is ins
3.46    FLJ42200   NM_207471   This record was removed by RefSeq staff.
2.31    FLJ42289   NM_207383   NM_207383.2 was permanently suppressed because currently there is su
2.78    FLJ43860     NM_207414 uncharacterized protein LOC389690
3.21    FLJ45983     NM_207423 NM_207423.1: This RefSeq was permanently suppressed because curren
-1.99   FLYWCH1      NM_032296 FLYWCH-type zinc finger-containing protein 1;FLYWCH1;ortholog
3.10    FMO1                                                   oxidoreductase activity
                     NM_002021 Dimethylaniline monooxygenase [N-oxide-forming] 1;FMO1;ortholog
-4.05   FMO5                                                   oxidoreductase activity
                     NM_001461 Dimethylaniline monooxygenase [N-oxide-forming] 5;FMO5;ortholog
-2.23   FMR1         NM_002024                                  protein;FMR1;ortholog
                                Fragile X mental retardation 1 RNA binding
2.03    FNTA                                                   acyltransferase activity
                     NM_002027 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
4.35    FOXA1                                                  transcription factor activity;transcription facto
                     NM_004496 Hepatocyte nuclear factor 3-alpha;FOXA1;ortholog
-2.39   FOXD1        NM_004472                                 transcription
                                Forkhead box protein D1;FOXD1;ortholog factor activity;transcription facto
4.78    FOXF2                                                  transcription
                     NM_001452 Forkhead box protein F2;FOXF2;ortholog factor activity;transcription facto
-2.26   FOXG1C       X74144                                    transcription
                                Forkhead box protein G1;FOXG1;ortholog factor activity;transcription facto
2.56    FOXL2        NM_023067                                 transcription
                                Forkhead box protein L2;FOXL2;ortholog factor activity;transcription facto
-2.36   FOXP2        NM_014491                                 transcription
                                Forkhead box protein P2;FOXP2;ortholog factor activity;transcription facto
6.06    FOXRED1                                                oxidoreductase activity
                     NM_017547 FAD-dependent oxidoreductase domain-containing protein 1;FOXRED1;or
2.39    FRG2                    Protein FRG2;FRG2;ortholog
                     NM_001005217
-3.18   FRMD7        NM_194277 FERM domain-containing protein 7;FRMD7;ortholog
-2.12   FRMD8        NM_031904 FERM domain-containing protein 8;FRMD8;ortholog
-2.31   FUCA1                                                  hydrolase activity, hydrolyzing N-glycosyl co
                     NM_000147 Tissue alpha-L-fucosidase;FUCA1;ortholog
-4.11   FURIN        NM_002569  Furin;FURIN;ortholog           serine-type peptidase activity
2.47    FVT1         NM_002035                                 oxidoreductase activity
                                3-ketodihydrosphingosine reductase;KDSR;ortholog
-3.88   FXYD2                                                  cation transmembrane transporter activity
                     NM_001680 Sodium/potassium-transporting ATPase gamma chain;FXYD2;ortholog
2.66    G3BP2                                                  RNA binding;receptor binding
                     NM_012297 Ras GTPase-activating protein-binding protein 2;G3BP2;ortholog
-2.24   GAB3         NM_080612 GRB2-associated-binding protein 3;GAB3;ortholog
2.19    GABARAP                                                structural constituent of cytoskeleton;microt
                     NM_007278 Gamma-aminobutyric acid receptor-associated protein;GABARAP;ortholo
-2.02   GABRB3                                                 GABA receptor activity;ligand-gated ion
                     NM_000814 Gamma-aminobutyric acid receptor subunit beta-3;GABRB3;ortholog chan
2.88    GABRP        NM_014211                                 GABA receptor activity;ligand-gated
                                Gamma-aminobutyric acid receptor subunit pi;GABRP;ortholog ion chan
3.02    GADD45B      NM_015675 Growth arrest and DNA-damage-inducible protein GADD45 beta;GADD45B
-2.26   GADD45GIP1   NM_052850 Growth arrest and DNA-damage-inducible proteins-interacting protein 1;GA
-1.99   GALE                                                   hydro-lyase
                     NM_000403 UDP-glucose 4-epimerase;GALE;ortholog activity;racemase and epimeras
-2.59   GALGT        NM_001478  Beta-1,4 N-acetylgalactosaminyltransferase 1;B4GALNT1;ortholog
2.72    GALNACT-2                                              transferase activity, transferring glycosyl gro
                     NM_018590 Chondroitin sulfate N-acetylgalactosaminyltransferase 2;CSGALNACT2;or
-2.14   GALNT10                                                transferase activity, transferring glycosyl
                     NM_017540 Polypeptide N-acetylgalactosaminyltransferase 10;GALNT10;ortholog gro
-3.05   GALR1        NM_001480                                 G-protein coupled receptor activity
                                Galanin receptor type 1;GALR1;ortholog
3.81    GAP43        NM_002045 Neuromodulin;GAP43;ortholog
2.08    GAPT         NM_152687 Uncharacterized protein C5orf29;C5orf29;ortholog
5.70    GAS1         NM_002048 Growth arrest-specific protein 1;GAS1;ortholog
-2.02   GASP2                                                   kunitz and NTR domain-containing protein 1
                     NM_138437 WAP, kazal, immunoglobulin,protein binding;serine-type endopeptidase in
4.36    GATA5                                                  nuclease activity;transcription factor activity;
                     NM_080473 Transcription factor GATA-5;GATA5;ortholog
2.08    GBP4                                                   GTPase activity;protein binding
                     NM_052941 Guanylate-binding protein 4;GBP4;ortholog
-2.73   GBP5         NM_052942                                 GTPase activity;protein binding
                                Guanylate-binding protein 5;GBP5;ortholog
2.22    GDAP2        NM_017686 Ganglioside-induced differentiation-associated protein 2;GDAP2;ortholog
-2.35   GDF9                                                   growth factor activity
                     NM_005260 Growth/differentiation factor 9;GDF9;ortholog
-2.96   GDI1         NM_001493                                 acyltransferase activity;protein binding;small
                                Rab GDP dissociation inhibitor alpha;GDI1;ortholog
-2.04   GDPD2                                                  phosphoric diester hydrolase activity;ligase a
                     NM_017711 Glycerophosphodiester phosphodiesterase domain-containing protein 2;GD
-2.77   GFI1B                                                  transcription
                     NM_004188 Zinc finger protein Gfi-1b;GFI1B;ortholog factor activity;transcription facto
2.83    GHRL         NM_016362  Obestatin;GHRL;ortholog        hormone activity
3.17    GJB3         NM_024009                                 gap junction
                                Gap junction beta-3 protein;GJB3;ortholog channel activity
-2.80   GJB6                                                   gap junction
                     NM_006783 Gap junction beta-6 protein;GJB6;ortholog channel activity
2.84    GKN1         NM_019617 Gastrokine-1;GKN1;ortholog
-2.07   GLRA2                                                  receptor activity;ligand-gated ion channel ac
                     NM_002063 Glycine receptor subunit alpha-2;GLRA2;ortholog
2.55    GLT8D1       NM_018446 Glycosyltransferase 8 domain-containing protein 1;GLT8D1;ortholog
-2.79   GLT8D2       NM_031302 Glycosyltransferase 8 domain-containing protein 2;GLT8D2;ortholog
5.72    GMEB1       NM_006582   Glucocorticoid modulatory element-binding protein 1;GMEB1;ortholog
2.79    GP1BB       NM_000407   Platelet glycoprotein Ib beta chain;GP1BB;ortholog
-2.35   GPD1        NM_005276                                    oxidoreductase activity
                                Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic;GPD1;ortholog
2.86    GPN2        NM_018066                                    nucleic
                                GPN-loop GTPase 2;GPN2;ortholog acid binding
7.24    GPR114      NM_153837                                    G-protein coupled receptor activity
                                Probable G-protein coupled receptor 114;GPR114;ortholog
3.06    GPR158      NM_020752   Probable G-protein coupled receptor 158;GPR158;ortholog
2.30    GRIA1       NM_000827                                    glutamate
                                Glutamate receptor 1;GRIA1;ortholog receptor activity;ligand-gated ion c
-3.19   GRIK4       NM_014619                                    glutamate receptor activity;ligand-gated ion c
                                Glutamate receptor, ionotropic kainate 4;GRIK4;ortholog
3.90    GRIN3A      NM_133445                                    glutamate receptor activity;ligand-gated ion c
                                Glutamate [NMDA] receptor subunit 3A;GRIN3A;ortholog
2.54    GRINL1A     NM_015532   Protein GRINL1A;GRINL1A;ortholog
6.46    GSDML       NM_018530   Gasdermin-B;GSDMB;ortholog
3.66    GSPT2       NM_018094                                    translation factor activity, nucleic acid bindin
                                Eukaryotic peptide chain release factor GTP-binding subunit ERF3B;GSPT
2.78    GTF2A1L     NM_006872                                    transcription factor activity;transcription facto
                                Transcription initiation factor IIA subunit 1-like;GTF2A1L;ortholog
-2.20   GTF2F1      NM_002096                                    transcription factor activity;transcription facto
                                General transcription factor IIF subunit 1;GTF2F1;ortholog
2.35    GUCA1C      NM_005459                                    calcium ion binding;calmodulin binding;smal
                                Guanylyl cyclase-activating protein 3;GUCA1C;ortholog
-2.57   HAMP        NM_021175   Hepcidin-20;HAMP;ortholog
2.47    HAND1       NM_004821                                    transcription factor activity;transcription facto
                                Heart- and neural crest derivatives-expressed protein 1;HAND1;ortholog
-2.34   HAPLN2      NM_021817   Hyaluronan and proteoglycan link protein 2;HAPLN2;ortholog
4.07    HBA2        NM_000517   Hemoglobin subunit alpha;HBA2;ortholog
-2.61   HBB         NM_000518   Hemoglobin subunit delta;HBD;ortholog
-2.35   HCA127      NM_018684   Hepatocellular carcinoma-associated antigen 127;HCA127;ortholog
-2.08   HDAC6       NM_006044                                    deacetylase
                                Histone deacetylase 6;HDAC6;ortholog activity;nucleic acid binding
2.78    HDAC7       NM_015401                                    deacetylase
                                Histone deacetylase 7;HDAC7;ortholog activity;nucleic acid binding
3.33    HEBP1       NM_015987   Heme-binding protein 1;HEBP1;ortholog
2.87    HEMGN       NM_018437   Hemogen;HEMGN;ortholog
3.10    HEMK        NM_016173                                    methyltransferase activity
                                HemK methyltransferase family member 1;HEMK1;ortholog
-2.99   HERC3       NM_014606                                    ubiquitin-protein ligase activity
                                Probable E3 ubiquitin-protein ligase HERC3;HERC3;ortholog
3.61    HERPUD2     NM_022373   Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like do
3.15    HEY1        NM_012258                                     with YRPW motif activity;transcription facto
                                Hairy/enhancer-of-split relatedtranscription factor protein 1;HEY1;ortholog
2.73    HEYL        NM_014571                                     with YRPW motif-like protein;HEYL;ortholog
                                Hairy/enhancer-of-split relatedtranscription factor activity;transcription facto
2.48    HIGD1B      NM_016438   HIG1 domain family member 1B;HIGD1B;ortholog
4.04    HINT1       NM_005340                                    nucleotide 1;HINT1;ortholog
                                Histidine triad nucleotide-binding protein phosphatase activity;nucleotide p
4.55    HIST1H2AJ   NM_021066                                    DNA binding
                                Histone H2A type 1-J;HIST1H2AJ;ortholog
1.99    HIST1H3I    NM_003533   Histone H3.1;HIST1H3J;ortholog
4.03    HKR3        NM_005341                                    transcription factor activity;transcription
                                Zinc finger and BTB domain-containing protein 48;ZBTB48;ortholog facto
-2.04   HLA-C       NM_002117   HLA class I histocompatibility antigen, Cw-7 alpha chain;HLA-C;ortholog
-3.22   HLA-DRB1    NM_002124   HLA class II histocompatibility antigen, DRB1-1 beta chain;HLA-DRB1;ort
3.75    HLX1        NM_021958                                    transcription
                                H2.0-like homeobox protein;HLX;ortholog factor activity;transcription facto
3.09    HLXB9       NM_005515                                    transcription factor activity;transcription facto
                                Motor neuron and pancreas homeobox protein 1;MNX1;ortholog
3.15    HMG1L10     NM_172363   High mobility group protein 1-like 10;HMG1L10;ortholog
2.29    HMGB3       NM_005342   High mobility group protein B3;HMGB3;ortholog
2.48    HN1         NM_016185   Hematological and neurological expressed 1 protein;HN1;ortholog
3.32    HNF1A       NM_000545                                    transcription factor activity;transcription facto
                                Hepatocyte nuclear factor 1-alpha;HNF1A;ortholog
-2.07   HNRPH1      NM_005520                                    structural constituent of ribosome;nucleic ac
                                Heterogeneous nuclear ribonucleoprotein H;HNRNPH1;ortholog
1.96    HOMER2      NM_004839                                    receptor binding
                                Homer protein homolog 2;HOMER2;ortholog
3.54    HOXA13      NM_000522                                    transcription factor
                                Homeobox protein Hox-A13;HOXA13;ortholog activity;transcription facto
-2.61   HOXB1       NM_002144                                    transcription
                                Homeobox protein Hox-B1;HOXB1;orthologfactor activity;transcription facto
-2.11   HOXB13      NM_006361                                    transcription factor
                                Homeobox protein Hox-B13;HOXB13;ortholog activity;transcription facto
-2.03   HOXC13      NM_017410                                    transcription factor
                                Homeobox protein Hox-C13;HOXC13;ortholog activity;transcription facto
4.57    HP1BP3      NM_016287   Heterochromatin protein 1-binding protein 3;HP1BP3;ortholog
2.30    HPCAL1      NM_002149                                    calcium ion binding;calmodulin binding
                                Hippocalcin-like protein 1;HPCAL1;ortholog
-2.20   HRG1        NM_017842   Heme transporter HRG1;Hrg1;ortholog
2.76    HRSP12     NM_005836   Ribonuclease UK114;HRSP12;ortholog
-2.45   HSPA2      NM_021979   Heat shock-related 70 kDa protein 2;HSPA2;ortholog
3.54    HSPC009    NM_014019   This record was removed by RefSeq staff; the sequence does not appear t
-2.49   HSYN       NM_018157   Synembryn-B;RIC8B;ortholog
-2.04   HTATSF1    NM_014500                                    RNA splicing
                               HIV Tat-specific factor 1;HTATSF1;ortholog factor activity, transesterificatio
2.64    HYDIN      NM_017558   Hydrocephalus-inducing protein homolog;HYDIN2;ortholog
3.02    IAPP       NM_000415                                    hormone
                               Islet amyloid polypeptide;IAPP;orthologactivity
2.23    IBSP       NM_004967   Bone sialoprotein 2;IBSP;orthologextracellular matrix structural constituent
2.52    ID4        NM_001546                                    transcription factor
                               DNA-binding protein inhibitor ID-4;ID4;ortholog activity;transcription facto
2.53    IDN3       NM_015384                                    nucleic
                               Nipped-B-like protein;NIPBL;ortholog acid binding;chromatin binding
2.03    IFFO1      NM_080730   Intermediate filament family orphan 1;IFFO1;ortholog
-1.97   IFI44      NM_006417   Interferon-induced protein 44;IFI44;ortholog
2.02    IFNA2      NM_000605   Interferon alpha-2;IFNA2;orthologhematopoietin/interferon-class (D200-domain
2.30    IFNA4      NM_021068   Interferon alpha-4;IFNA4;orthologhematopoietin/interferon-class (D200-domain
2.51    IFNAR2     NM_000874                                    beta chain;IFNAR2;ortholog
                               Interferon-alpha/beta receptor interferon receptor activity
5.73    IFNB1      NM_002176   Interferon beta;IFNB1;orthologhematopoietin/interferon-class (D200-domain
2.69    IFNG       NM_000619   Interferon gamma;IFNG;ortholog   hematopoietin/interferon-class (D200-domain
2.49    IFT20      NM_174887   Intraflagellar transport protein 20 homolog;IFT20;ortholog
-2.02   IGBP1      NM_001551   Immunoglobulin-binding protein 1;IGBP1;ortholog
2.87    IGFBP7     NM_001553   Insulin-like growth factor-binding protein 7;IGFBP7;ortholog
2.81    IGHG4      BC025985                                     antigen binding
                               Ig gamma-4 chain C region;IGHG4;ortholog
-2.21   IL13RA1    NM_001560                                    cytokine receptor activity
                               Interleukin-13 receptor alpha-1 chain;IL13RA1;ortholog
-2.88   IL1F9      NM_019618                                    hematopoietin/interferon-class (D200-domain
                               Interleukin-1 family member 9;IL1F9;ortholog
2.32    IL4        NM_000589   Interleukin-4;IL4;ortholog       hematopoietin/interferon-class (D200-domain
-2.12   IL6R       NM_000565                                    alpha;IL6R;ortholog
                               Interleukin-6 receptor subunit cytokine receptor activity
3.12    IL9R       NM_002186                                    cytokine receptor activity
                               Interleukin-9 receptor;IL9R;ortholog
-2.05   ILT7       NM_012276                                    receptor activity
                               Leukocyte immunoglobulin-like receptor subfamily A member 4;LILRA4;or
-2.89   INF2       NM_032714   Inverted formin-2;INF2;ortholog  structural constituent of cytoskeleton;actin b
2.33    INHBA      NM_002192                                    growth
                               Inhibin beta A chain;INHBA;ortholog factor activity
2.92    INPPL1     NM_001567   Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2;INPPL1;ortholog
-2.06   INSM1      NM_002196   Insulinoma-associated protein 1;INSM1;ortholog
4.22    INTS10     NM_018142   Integrator complex subunit 10;INTS10;ortholog
2.27    IQCC       NM_018134   IQ domain-containing protein C;IQCC;ortholog
-2.27   IREM2      NM_181449                                    receptor activity
                               CMRF35-like molecule 2;CD300E;ortholog
-2.08   IRF1       NM_002198                                    transcription
                               Interferon regulatory factor 1;IRF1;ortholog factor activity;transcription facto
2.52    IRF3       NM_001571                                    transcription
                               Interferon regulatory factor 3;IRF3;ortholog factor activity;transcription facto
-2.05   IRX4       NM_016358                                    transcription factor activity;transcription facto
                               Iroquois-class homeodomain protein IRX-4;IRX4;ortholog
-2.66   ITCH       NM_031483                                    ubiquitin-protein ligase activity
                               E3 ubiquitin-protein ligase Itchy homolog;ITCH;ortholog
-1.96   ITGA8      XM_167711   Integrin alpha-8 light chain;ITGA8;ortholog
-2.44   ITGAM      NM_000632   Integrin alpha-M;ITGAM;ortholog
2.48    IWS1       NM_017969   Protein IWS1 homolog;IWS1;ortholog
-2.40   IZUMO1     NM_182575   Izumo sperm-egg fusion protein 1;IZUMO1;ortholog
8.13    JMJD4      NM_023007                                    receptor activity
                               JmjC domain-containing protein 4;JMJD4;ortholog
2.55    JMJD8      XM_290722                                    receptor activity
                               JmjC domain-containing protein 8;JMJD8;ortholog
-2.29   KA21,KRT222P
                   NM_152349                                    structural constituent of cytoskeleton
                               Keratin-like protein KRT222;KRT222P;ortholog
-2.36   KBTBD7     NM_032138                                    structural constituent of cytoskeleton;actin b
                               Kelch repeat and BTB domain-containing protein 7;KBTBD7;ortholog
-2.48   KBTBD7     NM_032138                                    structural constituent of cytoskeleton;actin b
                               Kelch repeat and BTB domain-containing protein 7;KBTBD7;ortholog
-2.42   KCMF1      NM_020122   E3 ubiquitin-protein ligase KCMF1;KCMF1;ortholog
2.47    KCNC3      NM_004977                                    voltage-gated C member 3;KCNC3;ortholog
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
-3.63   KCNE1      NM_000219                                    voltage-gated E member 1;KCNE1;ortholog
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
2.44    KCNE1L     NM_012282                                    voltage-gated E member 1-like protein;KCNE
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
-2.06   KCNG1      NM_002237                                    voltage-gated G member 1;KCNG1;ortholog
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
4.32    KCNH6      NM_030779                                  receptor activity;voltage-gated potassium ch
                               Potassium voltage-gated channel subfamily H member 6;KCNH6;ortholog
2.53    KCNIP1     NM_014592                                   1;KCNIP1;ortholog
                               Kv channel-interacting protein calcium ion binding;protein binding;small GT
-2.53   KCNJ2      NM_000891                                  voltage-gated potassium
                               Inward rectifier potassium channel 2;KCNJ2;ortholog channel activity;volt
2.07    KCNK10     NM_021161                                   K member 10;KCNK10;ortholog
                               Potassium channel subfamily voltage-gated potassium channel activity;volt
2.23    KCNK15     NM_022358                                   K member 15;KCNK15;ortholog
                               Potassium channel subfamily voltage-gated potassium channel activity;volt
3.97    KCNQ2      NM_004518                                  voltage-gated KQT member 2;KCNQ2;orthol
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
2.71    KCNQ4      NM_004700                                  voltage-gated KQT member 4;KCNQ4;orthol
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
2.17    KCNS1      NM_002251                                  voltage-gated S member 1;KCNS1;ortholog
                               Potassium voltage-gated channel subfamily potassium channel activity;volt
2.25    KCTD15     NM_024076                                  protein binding
                               BTB/POZ domain-containing protein KCTD15;KCTD15;ortholog
2.87    KDELC1     NM_024089   KDEL motif-containing protein 1;KDELC1;ortholog
-2.68   KDELR3     NM_006855                                  receptor activity
                               ER lumen protein retaining receptor 3;KDELR3;ortholog
2.23    KIAA0179   XM_371417   Ribosomal RNA processing protein 1 homolog B;RRP1B;ortholog
-2.16   KIAA0643   NM_024793   Clusterin-associated protein 1;CLUAP1;ortholog
2.95    KIAA0676   NM_015043                                  9B;TBC1D9B;ortholog
                               TBC1 domain family member protein binding;small GTPase regulator activ
2.19    KIAA0774   XM_166270   Uncharacterized protein KIAA0774;KIAA0774;ortholog
2.74    KIAA1126   XM_050325                                  carbohydrate transmembrane transporter ac
                               Solute carrier family 45 member 4;SLC45A4;ortholog
2.43    KIAA1171   XM_370928                                  24;TBC1D24;ortholog
                               TBC1 domain family member protein binding;small GTPase regulator activ
5.27    KIAA1194   NM_015455                                  exoribonuclease activity;nucleic
                               CCR4-NOT transcription complex subunit 6;CNOT6;ortholog acid binding
3.40    KIAA1199   NM_018689   Protein KIAA1199;KIAA1199;ortholog
6.78    KIAA1202   XM_050478                                  receptor
                               Protein Shroom4;SHROOM4;ortholog activity;ligand-gated ion channel ac
2.25    KIAA1210   XM_172801   Uncharacterized protein KIAA1210;KIAA1210;ortholog
3.22    KIAA1211   XM_044178   Uncharacterized protein KIAA1211;KIAA1211;ortholog
-2.30   KIAA1267   NM_015443   Uncharacterized protein KIAA1267;KIAA1267;ortholog
-2.25   KIAA1305   XM_370756                                  nucleic protein KIAA1305;KIAA1305;ortholo
                               Integrase catalytic domain-containing acid binding
3.29    KIAA1333   NM_017769                                  double-stranded DNA binding
                               G2/M phase-specific E3 ubiquitin-protein ligase;KIAA1333;ortholog
-2.14   KIAA1370   XM_035527   Uncharacterized protein KIAA1370;KIAA1370;ortholog
-2.19   KIAA1393   XM_375085                                  methyltransferase activity
                               tRNA (guanine-N(1)-)-methyltransferase;TRMT5;ortholog
-2.43   KIAA1429   NM_015496   Protein virilizer homolog;KIAA1429;ortholog
-2.41   KIAA1456   NM_182598   Putative methyltransferase KIAA1456;C8orf79;ortholog
2.73    KIAA1462   XM_166132   Uncharacterized protein KIAA1462;KIAA1462;ortholog
2.61    KIAA1468   NM_020854   LisH domain and HEAT repeat-containing protein KIAA1468;KIAA1468;orth
5.58    KIAA1579   XM_371258                                  RNA splicing factor activity, transesterificatio
                               Ribonucleoprotein PTB-binding 2;RAVER2;ortholog
-2.70   KIAA1737   NM_033426   Uncharacterized protein KIAA1737;KIAA1737;ortholog
2.32    KIAA1786   XM_038436   Transmembrane protein 132B;TMEM132B;ortholog
-2.32   KIAA1853   XM_375000   Uncharacterized protein KIAA1853;KIAA1853;ortholog
2.91    KIAA1875   XM_291269   WD repeat-containing protein KIAA1875;KIAA1875;ortholog
5.60    KIAA1920   XM_375243   Uncharacterized protein KIAA1920;KIAA1920;ortholog
-2.64   KIAA1935   XM_087672                                  DNA-methyltransferase activity;nucleic acid
                               PWWP domain-containing protein 2A;PWWP2A;ortholog
-2.52   KIAA1975   XM_370567                                  nucleic acid binding;protein protein 11;AGA
                               Arf-GAP, GTPase, ANK repeat and PH domain-containingbinding;small GT
4.62    KIAA1991   XM_495886   RING finger protein 169;RNF169;ortholog
-3.26   KIAA2013   NM_138346   Uncharacterized protein KIAA2013;KIAA2013;ortholog
-3.03   KIF1B      NM_015074                                  microtubule
                               Kinesin-like protein KIF1B;KIF1B;ortholog motor activity;structural constitu
-2.58   KIF26A     XM_050278                                  microtubule motor activity;structural constitu
                               Kinesin-like protein KIF26A;KIF26A;ortholog
-2.54   KIF2B      NM_032559                                  microtubule
                               Kinesin-like protein KIF2B;KIF2B;ortholog motor activity;structural constitu
-3.05   KIF3A      NM_007054                                  microtubule
                               Kinesin-like protein KIF3A;KIF3A;ortholog motor activity;structural constitu
-2.49   KIF3C      NM_002254                                  microtubule
                               Kinesin-like protein KIF3C;KIF3C;ortholog motor activity;structural constitu
6.03    KIFC3      NM_005550                                  microtubule
                               Kinesin-like protein KIFC3;KIFC3;ortholog motor activity;structural constitu
-2.31   KIR2DL5    NM_020535                                   receptor 2DL5B;KIR2DL5B;ortholog
                               Killer cell immunoglobulin-likereceptor activity
4.20    KKLC1      XM_117548   Kita-kyushu lung cancer antigen 1;KKLC1;ortholog
2.21    KL         NM_153683   Klotho peptide;KL;ortholog glucosidase activity;hydrolase activity, hydro
2.71    KLC2       NM_022822                                  structural constituent of cytoskeleton
                               Kinesin light chain 2;KLC2;ortholog
2.78    KLF13      NM_015995                                  transcription factor activity;transcription facto
                               Krueppel-like factor 13;KLF13;ortholog
-2.14   KLHL7                                                 structural constituent of cytoskeleton;actin b
                    NM_018846 Kelch-like protein 7;KLHL7;ortholog
2.15    KLRC1                                                 receptor activity
                    NM_002259 NKG2-A/NKG2-B type II integral membrane protein;KLRC1;ortholog
-3.02   KNDC1       NM_033404                                 protein
                               Protein very KIND;KNDC1;ortholog binding;small GTPase regulator activ
2.85    KRI1        NM_023008 Protein KRI1 homolog;KRI1;ortholog
-2.78   KRT10                                                 structural constituent of cytoskeleton
                    NM_000421 Keratin, type I cytoskeletal 10;KRT10;ortholog
2.75    KRT23       NM_015515                                 structural constituent of cytoskeleton
                               Keratin, type I cytoskeletal 23;KRT23;ortholog
-3.23   KRT3                                                  structural constituent of cytoskeleton
                    NM_057088 Keratin, type II cytoskeletal 3;KRT3;ortholog
-2.15   KRT40                                                 structural constituent of cytoskeleton
                    NM_182497 Keratin, type I cytoskeletal 40;KRT40;ortholog
-2.15   KRT9        NM_000226                                 structural constituent of cytoskeleton
                               Keratin, type I cytoskeletal 9;KRT9;ortholog
7.99    KRTAP18-2                                             structural constituent of
                    NM_198693 Keratin-associated protein 10-2;KRTAP10-2;ortholog cytoskeleton
3.39    KRTAP19-1   NM_181607 Keratin-associated protein 19-1;KRTAP19-1;ortholog
-3.26   KRTAP4-5                                              structural constituent
                    NM_033188 Keratin-associated protein 4-5;KRTAP4-5;ortholog of cytoskeleton
2.18    KRTAP6-3    NM_181605 Keratin-associated protein 6-3;KRTAP6-3;ortholog
3.15    L3MBTL                                                transcription factor activity;chromatin binding
                    NM_015478 Lethal(3)malignant brain tumor-like protein;L3MBTL;ortholog
10.63   LAK                                                   protein kinase activity
                    NM_025144 Alpha-protein kinase 1;ALPK1;ortholog
2.53    LAMB1       NM_002291  Laminin subunit beta-1;LAMB1;ortholog
2.72    LAPTM4B                                               transmembrane 4B;LAPTM4B;ortholog
                    NM_018407 Lysosomal-associated transmembrane proteintransporter activity
3.68    LARP2       NM_018078 La-related protein 2;LARP2;ortholog
-2.20   LAS1L       NM_031206 LAS1-like protein;LAS1L;ortholog
4.47    LATS1                                                 protein kinase activity
                    NM_004690 Serine/threonine-protein kinase LATS1;LATS1;ortholog
2.99    LCE3D                                                 structural molecule activity
                    NM_032563 Late cornified envelope protein 3D;LCE3D;ortholog
3.08    LCK                                                   non-membrane spanning protein tyrosine kin
                    NM_005356 Proto-oncogene tyrosine-protein kinase LCK;LCK;ortholog
2.53    LDHA        NM_005566                                 oxidoreductase activity
                               L-lactate dehydrogenase A chain;LDHA;ortholog
3.15    LEF1                                                  nucleic acid binding
                    NM_016269 Lymphoid enhancer-binding factor 1;LEF1;ortholog
-2.36   LENEP       NM_018655 Lens epithelial cell protein LEP503;LENEP;ortholog
4.50    LGALS7      NM_002307 Galectin-7;LGALS7;ortholog
3.49    LIMA1       NM_016357 LIM domain and actin-binding structural constituent of cytoskeleton
                                                               protein 1;LIMA1;ortholog
-2.40   LMNA        NM_170707 Lamin-A/C;LMNA;ortholog structural constituent of cytoskeleton
4.09    LMO3                                                  transcription
                               LIM domain only protein 3;LMO3;ortholog factor activity;transcription facto
                    NM_001001395
6.13    LMO4        NM_006769                                 transcription factor activity;transcription facto
                               LIM domain transcription factor LMO4;LMO4;ortholog
-2.45   LNX                                                   structural constituent of cytoskeleton
                    NM_032622 E3 ubiquitin-protein ligase LNX;LNX1;ortholog
-2.05   LOC115110   XM_378828 This record was removed as a result of standard genome annotation proce
2.48    LOC143244   XM_084467 This record was removed as a result of standard genome annotation proce
5.59    LOC146110   XM_018432 This record was removed as a result of standard genome annotation proce
3.04    LOC154323   XM_098512 This record was removed as a result of standard genome annotation proce
2.08    LOC163301   XM_088797 This record was removed as a result of standard genome annotation proce
-2.14   LOC196337   XM_113696 This record was removed as a result of standard genome annotation proce
2.27    LOC202227   XM_116396 This record was removed as a result of standard genome annotation proce
3.77    LOC255519   XM_171766 This record was removed as a result of standard genome annotation proce
-2.19   LOC256283   XM_173105 This record was removed as a result of standard genome annotation proce
-2.06   LOC283480   XM_378430 This record was removed as a result of standard genome annotation proce
-2.60   LOC284837   NM_194310 NM_194310.1 was permanently suppressed because it is a nonsense-me
3.33    LOC284901   XM_209408 This record was removed as a result of standard genome annotation proce
-2.54   LOC284933   XM_379064 This record was removed as a result of standard genome annotation proce
-3.06   LOC285189   XM_376111 This record was removed as a result of standard genome annotation proce
3.03    LOC285248   XM_211816 This record was removed as a result of standard genome annotation proce
3.41    LOC285307   XM_211837 This record was removed as a result of standard genome annotation proce
2.20    LOC285311   XM_209563 NM_001007534.1: This RefSeq was permanently suppressed because cur
-2.51   LOC285422   XM_379280 This record was removed as a result of standard genome annotation proce
-2.25   LOC285972   XM_379530 This record was removed as a result of standard genome annotation proce
2.92    LOC286561   XM_210515 This record was removed as a result of standard genome annotation proce
2.50    LOC339782   XM_295062 This record was removed as a result of standard genome annotation proce
3.08    LOC339903   XM_291063   This record was removed as a result of standard genome annotation proce
2.69    LOC340148   XM_295166   This record was removed as a result of standard genome annotation proce
2.27    LOC341604   XM_296315   This record was removed as a result of standard genome annotation proce
1.98    LOC342600   XM_292624   This record was removed as a result of standard genome annotation proce
3.23    LOC344382   XM_293026   This record was removed as a result of standard genome annotation proce
2.00    LOC345576   XM_293886   This record was removed as a result of standard genome annotation proce
2.04    LOC345711   XM_293937   This record was removed as a result of standard genome annotation proce
2.39    LOC347265   XM_294590   This record was removed by RefSeq staff.
2.75    LOC360030   XM_370669   This record was removed as a result of standard genome annotation proce
2.47    LOC387649   XM_373452   This record was removed as a result of standard genome annotation proce
2.20    LOC387771   XM_373500   This record was removed as a result of standard genome annotation proce
2.70    LOC387810   XM_373513   This record was removed as a result of standard genome annotation proce
2.31    LOC387820   XM_370665   This record was removed as a result of standard genome annotation proce
2.54    LOC388305   XM_373700   This record was removed as a result of standard genome annotation proce
2.91    LOC388365   XM_373723   This record was removed as a result of standard genome annotation proce
2.10    LOC388554   XM_371182   This record was removed as a result of standard genome annotation proce
-2.13   LOC388924   XM_373974   This record was removed as a result of standard genome annotation proce
-2.08   LOC388929   XM_371480   This record was removed as a result of standard genome annotation proce
2.00    LOC389150   XM_374052   This record was removed as a result of standard genome annotation proce
4.01    LOC389204   XM_374079   This record was removed as a result of standard genome annotation proce
2.64    LOC389330   XM_374139   This record was removed as a result of standard genome annotation proce
2.22    LOC389403   XM_374172   This record was removed as a result of standard genome annotation proce
2.56    LOC389405   XM_371829   This record was removed as a result of standard genome annotation proce
2.75    LOC389490   XM_371901   This record was removed as a result of standard genome annotation proce
4.16    LOC389526   XM_374222   This record was removed as a result of standard genome annotation proce
3.72    LOC389602   XM_372004   This record was removed as a result of standard genome annotation proce
2.14    LOC389656   XM_374268   This record was removed as a result of standard genome annotation proce
-2.05   LOC389657   XM_374269   This record was removed as a result of standard genome annotation proce
2.08    LOC389674   XM_372050   This record was removed as a result of standard genome annotation proce
4.94    LOC389702   XM_374289   This record was removed as a result of standard genome annotation proce
2.35    LOC389753   XM_372112   This record was removed as a result of standard genome annotation proce
3.14    LOC390233   XM_372424   This record was removed as a result of standard genome annotation proce
-3.66   LOC390256   XM_372432   This record was removed as a result of standard genome annotation proce
3.21    LOC390488   XM_372527   This record was removed as a result of standard genome annotation proce
3.76    LOC390547   XM_372553   This record was removed as a result of standard genome annotation proce
1.98    LOC391749   XM_373061   This record was removed as a result of standard genome annotation proce
14.60   LOC391769   XM_373079   This record was removed as a result of standard genome annotation proce
2.63    LOC392179   XM_373233   This record was removed as a result of standard genome annotation proce
2.73    LOC392238   XM_374372   This record was removed as a result of standard genome annotation proce
7.18    LOC392347   XM_373298   This record was removed as a result of standard genome annotation proce
2.12    LOC392395   XM_373319   NM_001013664.1: This RefSeq was temporarily suppressed because the
2.08    LOC392749   XM_374741   This record was removed as a result of standard genome annotation proce
-3.44   LOC399788   XM_374817   This record was removed as a result of standard genome annotation proce
4.25    LOC399937   XM_374917   This record was removed as a result of standard genome annotation proce
2.29    LOC400043   XM_378360   This record was removed as a result of standard genome annotation proce
2.13    LOC400214   XM_375081   This record was removed as a result of standard genome annotation proce
2.13    LOC400298   XM_375147   This record was removed as a result of standard genome annotation proce
2.50    LOC400552   XM_378623   This record was removed as a result of standard genome annotation proce
2.27    LOC400813   XM_378947   This record was removed as a result of standard genome annotation proce
2.91    LOC401014   XM_379141   This record was removed as a result of standard genome annotation proce
-2.10   LOC401015   XM_376148   This record was removed as a result of standard genome annotation proce
-2.51   LOC401016   XM_376150   This record was removed as a result of standard genome annotation proce
2.75    LOC401062   XM_379190   This record was removed as a result of standard genome annotation proce
-2.00   LOC401087   XM_376267   This record was removed as a result of standard genome annotation proce
-2.30   LOC401095   XM_376278   This record was removed as a result of standard genome annotation proce
2.40    LOC401180   XM_379325   uncharacterized LOC401180
3.03    LOC401207   XM_376423   This record was removed as a result of standard genome annotation proce
2.28    LOC401234   XM_379395   This record was removed as a result of standard genome annotation proce
2.51    LOC401252   XM_376488   NM_001013681.1 was permanently suppressed because currently there is
2.82    LOC401254   XM_379406   This record was removed as a result of standard genome annotation proce
2.42    LOC401284   XM_379454   This record was removed as a result of standard genome annotation proce
2.84    LOC401352   XM_379493   This record was removed as a result of standard genome annotation proce
2.73    LOC401394   XM_379512   This record was removed as a result of standard genome annotation proce
2.71    LOC401434   XM_379531   This record was removed as a result of standard genome annotation proce
2.61    LOC401539   XM_379648   This record was removed as a result of standard genome annotation proce
2.27    LOC401543   XM_379656   This record was removed as a result of standard genome annotation proce
2.95    LOC401552   XM_379668   This record was removed as a result of standard genome annotation proce
2.22    LOC401983   XM_377630   This record was removed as a result of standard genome annotation proce
3.13    LOC402203   XM_377880   This record was removed as a result of standard genome annotation proce
4.91    LOC402245   XM_377926   This record was removed as a result of standard genome annotation proce
4.02    LOC402251   XM_377933   This record was removed as a result of standard genome annotation proce
-2.73   LOC402340   XM_378033   This record was removed as a result of standard genome annotation proce
2.66    LOC402455   XM_374713   This record was removed as a result of standard genome annotation proce
3.22    LOC402461   XM_379786   This record was removed as a result of standard genome annotation proce
2.67    LOC402490   XM_379820   This record was removed as a result of standard genome annotation proce
3.53    LOC402515   XM_380112   This record was removed as a result of standard genome annotation proce
2.91    LOC402516   XM_380113   This record was removed as a result of standard genome annotation proce
3.35    LOC402539   XM_379858   This record was removed as a result of standard genome annotation proce
3.03    LOC402596   XM_380146   This record was removed as a result of standard genome annotation proce
2.35    LOC402620   XM_379962   NM_001004302.2: This RefSeq was permanently suppressed because cur
2.76    LOC85028    XM_378848   This record was removed as a result of standard genome annotation proce
3.13    LOC91632    XM_039721   NM_001080422.1: This RefSeq was permanently suppressed because it is
2.47    LOC92017    XM_042234   NM_001009607.1: This RefSeq was permanently suppressed because the
-2.63   LOC93463    XM_376186   This record was removed as a result of standard genome annotation proce
-2.80   LPA         NM_005577   Apolipoprotein(a);LPA;orthologserine-type peptidase activity;calcium ion bin
2.24    LPXN        NM_004811   Leupaxin;LPXN;ortholog        structural constituent of cytoskeleton
-2.22   LRCH3       NM_032773   Leucine-rich repeat and calponin homology domain-containing protein 3;LR
2.24    LRFN1       XM_290842                                 receptor activity
                                Leucine-rich repeat and fibronectin type III domain-containing protein 1;LRF
-2.33   LRP12       NM_013437                                 receptor activity
                                Low-density lipoprotein receptor-related protein 12;LRP12;ortholog
-2.78   LRP15       NM_052953                                   protein activity
                                Leucine-rich repeat-containingreceptor 3B;LRRC3B;ortholog
3.08    LRP16       NM_014067   MACRO domain-containing protein 1;MACROD1;ortholog
3.85    LRP2BP      NM_018409                                 protein binding;enzyme regulator activity
                                LRP2-binding protein;LRP2BP;ortholog
-2.45   LRP5        NM_002335                                 receptor activity
                                Low-density lipoprotein receptor-related protein 5;LRP5;ortholog
-2.28   LRPAP1      NM_002337                                 lipid transporter activity
                                Alpha-2-macroglobulin receptor-associated protein;LRPAP1;ortholog
3.00    LRRC1       NM_018214   Leucine-rich repeat-containing protein 1;LRRC1;ortholog
-2.25   LRRC16      NM_017640   Leucine-rich repeat-containing protein 16A;LRRC16A;ortholog
3.70    LRRC20      NM_018205   Leucine-rich repeat-containing protein 20;LRRC20;ortholog
-2.34   LRRC45      NM_144999   Leucine-rich repeat-containing protein 45;LRRC45;ortholog
2.75    LRRN1       NM_020873                                 receptor activity
                                Leucine-rich repeat neuronal protein 1;LRRN1;ortholog
-2.43   LRRTM4      NM_024993                                 receptor activity
                                Leucine-rich repeat transmembrane neuronal protein 4;LRRTM4;ortholog
2.99    LRTM1       NM_020678                                 receptor activity
                                Leucine-rich repeat and transmembrane domain-containing protein 1;LRTM
3.18    LSM3        NM_014463                                 RNA splicing factor activity, transesterificatio
                                U6 snRNA-associated Sm-like protein LSm3;LSM3;ortholog
-2.34   LY96        NM_015364   Lymphocyte antigen 96;LY96;ortholog
2.02    LYZL6       NM_020426                                 hydrolase
                                Lysozyme-like protein 6;LYZL6;ortholog activity
2.65    LZTFL1     NM_020347   Leucine zipper transcription factor-like protein 1;LZTFL1;ortholog
2.21    MACC1      NM_182762   SH3 domain-containing protein 7a5;7A5_HUMAN;ortholog
-2.24   MADD       NM_003682                                   protein protein;MADD;ortholog
                               MAP kinase-activating death domain binding;small GTPase regulator activ
1.97    MAGEC2     NM_016249   Melanoma-associated antigen C2;MAGEC2;ortholog
-2.68   MAJN       NM_004740   Myosin-XVIIIa;MYO18A;ortholog   motor activity;structural constituent of cytosk
2.13    MAN1       NM_014319   Inner nuclear membrane protein Man1;LEMD3;ortholog
-2.79   MANEA      NM_024641                                   hydrolase activity, hydrolyzing
                               Glycoprotein endo-alpha-1,2-mannosidase;MANEA;ortholog N-glycosyl co
2.60    MAP17      NM_005764   PDZK1-interacting protein 1;PDZK1IP1;ortholog
2.32    MAP2       NM_002374                                   structural constituent
                               Microtubule-associated protein 2;MAP2;ortholog of cytoskeleton;microt
8.38    MAPK13     NM_002754                                   protein kinase activity
                               Mitogen-activated protein kinase 13;MAPK13;ortholog
4.92    MAPK14     NM_001315                                   protein kinase activity
                               Mitogen-activated protein kinase 14;MAPK14;ortholog
3.18    MAPKAPK2 NM_004759                                      kinase 2;MAPKAPK2;ortholog
                               MAP kinase-activated protein protein kinase activity
-2.27   MAPRE1     NM_012325                                   structural constituent of 1;MAPRE1;ortholog
                               Microtubule-associated protein RP/EB family member cytoskeleton;microt
4.25    MAPT       NM_005910                                   structural constituent
                               Microtubule-associated protein tau;MAPT;ortholog of cytoskeleton;microt
-2.24   MAST1      NM_014975                                   protein kinase activity
                               Microtubule-associated serine/threonine-protein kinase 1;MAST1;ortholog
4.76    MAST2      NM_015112                                   protein kinase activity
                               Microtubule-associated serine/threonine-protein kinase 2;MAST2;ortholog
-3.07   MBD4       NM_003925                                   methyltransferase activity;nuclease activity;n
                               Methyl-CpG-binding domain protein 4;MBD4;ortholog
2.43    MCTS1      NM_014060                                   receptor activity
                               Malignant T cell amplified sequence 1;MCTS1;ortholog
-2.55   METRNL     XM_209073   Meteorin-like protein;METRNL;ortholog
2.11    METTL5     NM_014168   Methyltransferase-like protein 5;METTL5;ortholog
-2.51   MGC16121   NM_032762   NM_032762.2: This RefSeq was permanently suppressed because it is no
3.08    MGC21881   NM_203448   NM_203448.1 was permanently suppressed because currently there is su
-2.22   MGC39821   NM_182576   This record was removed by RefSeq staff; the sequence does not appear t
-2.51   MGC50722   NM_203348   uncharacterized MGC50722 (MGC50722), mRNA
2.60    MGC9515    XM_375313   This record was removed as a result of standard genome annotation proce
9.60    MIA        NM_006533   Melanoma-derived growth regulatory protein;MIA;ortholog
-3.15   MIP        NM_012064                                   transmembrane
                               Lens fiber major intrinsic protein;MIP;ortholog transporter activity
19.18   MITF       NM_000248                                   transcription factor activity;transcription facto
                               Microphthalmia-associated transcription factor;MITF;ortholog
-2.43   MLH3       NM_014381                                   Mlh3;MLH3;ortholog
                               DNA mismatch repair protein DNA binding
2.50    MLL        NM_005933                                   methyltransferase activity;DNA binding
                               Histone-lysine N-methyltransferase HRX;MLL;ortholog
5.77    MLL3       NM_021230                                   methyltransferase activity;DNA binding
                               Histone-lysine N-methyltransferase MLL3;MLL3;ortholog
3.23    MLSTD2     NM_032228                                   oxidoreductase
                               Fatty acyl-CoA reductase 1;FAR1;ortholog activity
-2.28   MMP12      NM_002426                                   metallopeptidase
                               Macrophage metalloelastase;MMP12;ortholog activity
2.30    MMP2       NM_004530                                   metallopeptidase activity
                               72 kDa type IV collagenase;MMP2;ortholog
2.45    MMP24      NM_006690                                   metallopeptidase activity
                               Processed matrix metalloproteinase-24;MMP24;ortholog
-2.55   MMP8       NM_002424                                   metallopeptidase activity
                               Neutrophil collagenase;MMP8;ortholog
2.23    MNS1       NM_018365                                   structural molecule activity
                               Meiosis-specific nuclear structural protein 1;MNS1;ortholog
2.30    MOAP1      NM_022151   Modulator of apoptosis 1;MOAP1;ortholog
3.00    MOGAT1,DC2 NM_058165                                   acyltransferase activity
                               2-acylglycerol O-acyltransferase 1;MOGAT1;ortholog
8.12    MPP1       NM_002436                                   nucleotide kinase activity;protein kinase acti
                               55 kDa erythrocyte membrane protein;MPP1;ortholog
7.79    MRPL20     NM_017971                                   structural constituent of ribosome;nucleic ac
                               39S ribosomal protein L20, mitochondrial;MRPL20;ortholog
-2.88   MRPL36,BRIP1
                   NM_032479   39S ribosomal protein L36, mitochondrial;MRPL36;ortholog
2.78    MRPL40     NM_003776                                   structural constituent of ribosome;nucleic ac
                               39S ribosomal protein L40, mitochondrial;MRPL40;ortholog
3.26    MRPL46     NM_022163                                   structural constituent of ribosome;nucleic ac
                               39S ribosomal protein L46, mitochondrial;MRPL46;ortholog
2.47    MRPS12     NM_021107                                   structural constituent of ribosome;nucleic ac
                               28S ribosomal protein S12, mitochondrial;MRPS12;ortholog
-2.20   MRPS18A    NM_018135                                   structural constituent of ribosome;nucleic ac
                               28S ribosomal protein S18a, mitochondrial;MRPS18A;ortholog
3.24    MRPS23     NM_016070                                   structural constituent of ribosome;nucleic ac
                               28S ribosomal protein S23, mitochondrial;MRPS23;ortholog
3.43    MRPS33     NM_016071                                   structural constituent of ribosome;nucleic ac
                               28S ribosomal protein S33, mitochondrial;MRPS33;ortholog
5.28    MRPS7      NM_015971                                   structural constituent of ribosome;nucleic ac
                               28S ribosomal protein S7, mitochondrial;MRPS7;ortholog
3.94    MRRF       NM_138777                                   structural constituent of ribosome;nucleic ac
                               Ribosome-recycling factor, mitochondrial;MRRF;ortholog
2.02    MRVLDC3    NM_052858                                   transcription factor activity;protein binding;tra
                               MARVEL domain-containing protein 3;MARVELD3;ortholog
3.24    MS4A1      NM_021950                                   receptor activity
                               B-lymphocyte antigen CD20;MS4A1;ortholog
-2.08   MSH4      NM_002440                                    damaged
                              MutS protein homolog 4;MSH4;orthologDNA binding
3.83    MSN       NM_002444   Moesin;MSN;ortholog              structural constituent of cytoskeleton
2.95    MSRA      NM_012331                                    oxidoreductase activity
                              Peptide methionine sulfoxide reductase;MSRA;ortholog
-2.46   MSX2      NM_002449                                    transcription
                              Homeobox protein MSX-2;MSX2;ortholog factor activity;transcription facto
2.88    MTHFD2    NM_006636                                    oxidoreductase activity;hydrolase activity;lig
                              Methenyltetrahydrofolate cyclohydrolase;MTHFD2;ortholog
-2.93   MTMR8     NM_017677   Myotubularin-related protein 8;MTMR8;ortholog
-2.81   MTRF1L    NM_019041                                    translation factor activity, nucleic acid
                              Peptide chain release factor 1-like, mitochondrial;MTRF1L;ortholog bindin
-2.38   MUC12     XM_379904   Mucin-12;MUC12;ortholog
4.06    MVK       NM_000431   Mevalonate kinase;MVK;ortholog   kinase activity
2.38    MYC       NM_002467                                    transcription
                              Myc proto-oncogene protein;MYC;ortholog factor activity;transcription facto
-2.68   MYH7      NM_000257   Myosin-7;MYH7;ortholog           motor activity;structural constituent of cytosk
5.31    MYH9      NM_002473   Myosin-9;MYH9;ortholog           motor activity;structural constituent of cytosk
-3.40   MYL4      NM_002476                                    structural constituent of cytoskeleton;calcium
                              Myosin light chain 4;MYL4;ortholog
4.13    MYL9      NM_006097                                    structural constituent of
                              Myosin regulatory light polypeptide 9;MYL9;ortholog cytoskeleton;calcium
2.82    MYLK2     NM_033118                                    protein kinase muscle;MYLK2;ortholog
                              Myosin light chain kinase 2, skeletal/cardiacactivity
-2.20   MYPN      NM_032578   Myopalladin;MYPN;ortholog structural constituent of cytoskeleton
2.57    NAALAD2   NM_005467                                    peptidase activity
                              N-acetylated-alpha-linked acidic dipeptidase 2;NAALAD2;ortholog
2.83    NALP10    NM_176821   NACHT, LRR and PYD domains-containing protein 10;NLRP10;ortholog
3.44    NALP14    NM_176822   NACHT, LRR and PYD domains-containing protein 14;NLRP14;ortholog
3.37    NAT14     NM_020378   N-acetyltransferase 14;NAT14;ortholog
-2.24   NBPF14    NM_015383   Neuroblastoma breakpoint family member 14;NBPF14;ortholog
3.23    NCAM2     NM_004540                                      2;NCAM2;ortholog
                              Neural cell adhesion moleculephosphoprotein phosphatase activity;phosph
4.47    NCBP1     NM_002486                                    RNA 1;NCBP1;ortholog
                              Nuclear cap-binding protein subunitsplicing factor activity, transesterificatio
-2.03   NCF2      NM_000433                                    oxidoreductase activity
                              Neutrophil cytosol factor 2;NCF2;ortholog
-2.11   NCKAP1    NM_013436   Nck-associated protein 1;NCKAP1;ortholog
-2.26   NCOA5     NM_020967                                    receptor activity
                              Nuclear receptor coactivator 5;NCOA5;ortholog
-2.33   NCOA7     NM_181782   Nuclear receptor coactivator 7;NCOA7;ortholog
3.21    NDST2     NM_003635                                    transferase activity
                              Heparan sulfate N-sulfotransferase 2;NDST2;ortholog
3.95    NDUFAF1   NM_016013   Complex I intermediate-associated protein 30, mitochondrial;NDUFAF1;or
2.44    NDUFB6    NM_002493   NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;NDUFB6
3.06    NECAP1    NM_015509                                    ATPase activity, coupled to transmembrane
                              Adaptin ear-binding coat-associated protein 1;NECAP1;ortholog
-2.67   NEURL     NM_004210                                    ubiquitin-protein ligase activity
                              Neuralized-like protein 1;NEURL;ortholog
2.72    NEUROG2   NM_024019   Neurogenin-2;NEUROG2;ortholog    nuclease activity;transcription factor activity;
3.56    NF2       NM_000268   Merlin;NF2;ortholog              structural constituent of cytoskeleton
3.49    NFE2L1    NM_003204                                    transcription factor activity;transcription facto
                              Nuclear factor erythroid 2-related factor 1;NFE2L1;ortholog
2.31    NFE2L3    NM_004289                                    transcription factor activity;transcription facto
                              Nuclear factor erythroid 2-related factor 3;NFE2L3;ortholog
5.20    NFIC      NM_005597                                    transcription factor activity;transcription facto
                              Nuclear factor 1 C-type;NFIC;ortholog
-2.16   NFKBIE    NM_004556   NF-kappa-B inhibitor epsilon;NFKBIE;ortholog
2.91    NID2      NM_007361   Nidogen-2;NID2;ortholog          receptor activity
-2.41   NIP30     NM_024946   NEFA-interacting nuclear protein NIP30;NIP30;ortholog
4.66    NIP7      NM_016101   60S ribosome subunit biogenesis protein NIP7 homolog;NIP7;ortholog
-2.28   NLN       NM_020726                                    metallopeptidase activity
                              Neurolysin, mitochondrial;NLN;ortholog
2.88    NME4      NM_005009                                    nucleotide kinase activity
                              Nucleoside diphosphate kinase, mitochondrial;NME4;ortholog
3.56    NOG       NM_005450   Noggin;NOG;ortholog              receptor binding
5.96    NOL8      NM_017948   Nucleolar protein 8;NOL8;ortholog
3.74    NOLA1     NM_018983                                    structural constituent of ribosome;nucleic ac
                              H/ACA ribonucleoprotein complex subunit 1;GAR1;ortholog
3.53    NPDC1     NM_015392                                    transcription factor activity;transcription facto
                              Neural proliferation differentiation and control protein 1;NPDC1;ortholog
-2.43   NPEPPS    NM_006310                                    metallopeptidase activity
                              Puromycin-sensitive aminopeptidase;NPEPPS;ortholog
-2.33   NR5A1     NM_004959                                    ligand-dependent nuclear receptor activity;tra
                              Steroidogenic factor 1;NR5A1;ortholog
-2.38   NRCAM     NM_005010                                    phosphoprotein phosphatase activity;phosph
                              Neuronal cell adhesion molecule;NRCAM;ortholog
-2.25   NRIP2     NM_031474                                    aspartic-type endopeptidase activity;transcri
                              Nuclear receptor-interacting protein 2;NRIP2;ortholog
-2.80   NRN1      NM_016588   Neuritin;NRN1;ortholog
3.92    NSFL1C    NM_016143 NSFL1 cofactor p47;NSFL1C;ortholog
2.88    NSMAF     NM_003580 Protein FAN;NSMAF;orthologprotein binding
6.04    NSUN2                                               methyltransferase activity;nucleic
                  NM_017755 tRNA (cytosine-5-)-methyltransferase NSUN2;NSUN2;ortholog acid bindin
-2.34   NTN2L     NM_006181 Netrin-2-like protein;NTN2L;ortholog
-2.62   NTN4      NM_021229 Netrin-4;NTN4;ortholog
-2.61   NUCB1     NM_006184 Nucleobindin-1;NUCB1;ortholog   nucleic acid binding;calcium ion binding;calm
-2.18   NUDT10    NM_153183 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha;NUDT10;ortho
-3.48   NXF       NM_178864 Neuronal PAS domain-containing protein 4;NPAS4;ortholog
-2.74   OASL                                                nucleotidyltransferase activity;nucleic
                  NM_003733 59 kDa 2'-5'-oligoadenylate synthetase-like protein;OASL;ortholog acid b
-3.39   OAZ2                                                protein binding;enzyme
                  NM_002537 Ornithine decarboxylase antizyme 2;OAZ2;ortholog inhibitor activity
2.71    OCEL1                                               transcription factor activity;transcription facto
                  NM_024578 Occludin/ELL domain-containing protein 1;OCEL1;ortholog
2.30    OCSP      NM_031945                                 receptor binding
                              Tetraspanin-10;TSPAN10;ortholog
3.24    ODAG      NM_021167                                 transcription factor activity;transcription facto
                              GATA zinc finger domain-containing protein 1;GATAD1;ortholog
3.98    OGFOD1                                              oxidoreductase domain-containing protein
                  NM_018233 2-oxoglutarate and iron-dependent oxygenaseactivity;transferase activity 1
-2.81   OGFR                                                receptor activity
                  NM_007346 Opioid growth factor receptor;OGFR;ortholog
-2.56   OGFRL1    NM_024576                                 receptor activity
                              Opioid growth factor receptor-like protein 1;OGFRL1;ortholog
4.50    OLFML3                                              receptor activity
                  NM_020190 Olfactomedin-like protein 3;OLFML3;ortholog
-2.37   OPLAH     NM_017570 5-oxoprolinase;OPLAH;ortholog   hydrolase activity
2.51    OR10H5    XM_210787 Olfactory receptor 10H5;OR10H5;ortholog
2.63    OR1B1     XM_294534 Olfactory receptor 1B1;OR1B1;ortholog
-2.43   OR1J2     XM_373313 Olfactory receptor 1J2;OR1J2;ortholog
2.11    OR2K2     NM_205859 Olfactory receptor 2K2;OR2K2;ortholog
3.48    OR4F21    NM_001005504Olfactory receptor 4F21;OR4F21;ortholog
4.76    OR52A5    XM_372352 Olfactory receptor 52A5;OR52A5;ortholog
2.57    OR52H1    NM_001005289Olfactory receptor 52H1;OR52H1;ortholog
2.07    OR5K1     XM_372997 Olfactory receptor 5K1;OR5K1;ortholog
2.44    OR5L2     XM_372387 Olfactory receptor 5L2;OR5L2;ortholog
2.01    OR6B1     XM_374682 Olfactory receptor 6B1;OR6B1;ortholog
2.42    ORC3L                                               DNA 3;ORC3L;ortholog
                  NM_012381 Origin recognition complex subunit replication origin binding
-2.19   ORMDL3    NM_139280   ORM1-like protein 3;ORMDL3;ortholog
-2.70   OSBPL6    NM_032523 Oxysterol-binding protein-related protein 6;OSBPL6;ortholog
-2.54   OSGEPL1                                             metallopeptidase activity
                  NM_022353 Probable O-sialoglycoprotein endopeptidase 2;OSGEPL1;ortholog
2.15    OSTF1     NM_012382   Osteoclast-stimulating factor 1;OSTF1;ortholog
2.36    OTP                                                 transcription factor activity;transcription facto
                  NM_032109 Homeobox protein orthopedia;OTP;ortholog
-2.11   OTUD5                                               peptidase activity;nucleic acid binding
                  NM_017602 OTU domain-containing protein 5;OTUD5;ortholog
9.50    OVTN      NM_198185 Ovochymase-2;OVCH2;ortholog     serine-type peptidase activity
3.63    PAIP2     NM_016480   Polyadenylate-binding protein-interacting protein 2;PAIP2;ortholog
-2.18   PALB2     NM_024675 Partner and localizer of BRCA2;PALB2;ortholog
2.67    PALM      NM_002579 Paralemmin;PALM;ortholog
5.81    PAPD1                                               nucleotidyltransferase activity
                  NM_018109 Poly(A) RNA polymerase, mitochondrial;PAPD1;ortholog
-3.34   PAPLN     XM_370765 Papilin;PAPLN;ortholog          protein binding;serine-type endopeptidase in
-1.96   PAPPA     NM_002581 Pappalysin-1;PAPPA;ortholog     metallopeptidase activity
-1.99   PARF      NM_024718                                 GTPase activity;protein binding
                              Putative GTP-binding protein Parf;PARF;ortholog
2.40    PARP16    NM_017851 Poly [ADP-ribose] polymerase 16;PARP16;ortholog
5.49    PARPBP    NM_017915 UPF0419 protein C12orf48;C12orf48;ortholog
4.63    PASK                                                transmembrane receptor protein kinase activ
                  NM_015148 PAS domain-containing serine/threonine-protein kinase;PASK;ortholog
-2.14   PAX3      NM_000438                                 transcription
                              Paired box protein Pax-3;PAX3;ortholog factor activity;transcription facto
-2.33   PCDH18                                              calcium
                  NM_019035 Protocadherin-18;PCDH18;ortholog ion binding
-2.47   PCDH19                                              calcium
                              Protocadherin-19;PCDH19;ortholog ion binding
                  XM_033173, NM_020766
-2.34   PCDHA9    NM_014005                                 calcium ion
                              Protocadherin alpha-9;PCDHA9;ortholog binding
-2.39   PCDHB13                                             calcium ion
                  NM_018933 Protocadherin beta-13;PCDHB13;ortholog binding
3.25    PCDHB4                                              calcium ion
                  NM_018938 Protocadherin beta-4;PCDHB4;ortholog binding
-2.52   PCDHB7     NM_018940                                  calcium ion
                               Protocadherin beta-7;PCDHB7;ortholog binding
-2.02   PCDHGA1    NM_018912                                  calcium ion binding
                               Protocadherin gamma-A1;PCDHGA1;ortholog
2.57    PCDHGA11   NM_018914                                  calcium ion binding
                               Protocadherin gamma-A11;PCDHGA11;ortholog
3.99    PCDHGA12   NM_003735                                  calcium ion binding
                               Protocadherin gamma-A12;PCDHGA12;ortholog
2.99    PCDHGA5    NM_018918                                  calcium ion binding
                               Protocadherin gamma-A5;PCDHGA5;ortholog
-2.21   PCDHGA9    NM_018921                                  calcium ion binding
                               Protocadherin gamma-A9;PCDHGA9;ortholog
3.23    PCDHGB3    NM_018924                                  calcium ion binding
                               Protocadherin gamma-B3;PCDHGB3;ortholog
3.71    PCDHGB7    NM_018927                                  calcium ion binding
                               Protocadherin gamma-B7;PCDHGB7;ortholog
-2.59   PCNXL2     NM_014801   Pecanex-like protein 2;PCNXL2;ortholog
-2.29   PCOLCE2    NM_013363                                   enhancer 2;PCOLCE2;ortholog
                               Procollagen C-endopeptidase metallopeptidase activity;serine-type peptida
4.00    PCQAP      NM_015889   Mediator of RNA polymerase II transcription subunit 15;MED15;ortholog
6.59    PCTK2      NM_002595                                  protein kinase activity
                               Serine/threonine-protein kinase PCTAIRE-2;PCTK2;ortholog
3.76    PDCD1LG1   NM_014143   Programmed cell death 1 ligand 1;CD274;ortholog
-2.45   PDCD1LG2   NM_025239   Programmed cell death 1 ligand 2;PDCD1LG2;ortholog
5.99    PDGFA      NM_002607                                  growth A;PDGFA;ortholog
                               Platelet-derived growth factor subunit factor activity
2.57    PDZRN4     NM_013377   PDZ domain-containing RING finger protein 4;PDZRN4;ortholog
3.05    PEPD       NM_000285                                  metallopeptidase activity;transcription factor
                               Xaa-Pro dipeptidase;PEPD;ortholog
-2.69   PEX10      NM_002617   Peroxisome assembly protein 10;PEX10;ortholog
2.38    PGAM1      NM_002629                                  intramolecular transferase activity
                               Phosphoglycerate mutase 1;PGAM1;ortholog
-2.19   PGAP1      NM_024989                                  transmembrane transporter activity
                               GPI inositol-deacylase;PGAP1;ortholog
3.56    PGLS       NM_012088                                  hydrolase activity
                               6-phosphogluconolactonase;PGLS;ortholog
-2.77   PGLYRP4    NM_020393                                  receptor activity;receptor binding
                               Peptidoglycan recognition protein I-beta;PGLYRP4;ortholog
3.81    PGPEP1     NM_017712                                  cysteine-type
                               Pyroglutamyl-peptidase 1;PGPEP1;orthologpeptidase activity
2.43    PHAX       NM_032177                                  export protein;PHAX;ortholog
                               Phosphorylated adapter RNA RNA binding
4.73    PHF10      NM_018288                                  acetyltransferase activity;transcription factor
                               PHD finger protein 10;PHF10;ortholog
5.58    PHF21B     NM_138415                                  ubiquitin-protein ligase activity
                               PHD finger protein 21B;PHF21B;ortholog
-2.67   PHGDH      NM_006623                                  oxidoreductase activity
                               D-3-phosphoglycerate dehydrogenase;PHGDH;ortholog
-2.16   PHYH       NM_006214                                  peroxisomal;PHYH;ortholog
                               Phytanoyl-CoA dioxygenase, oxidoreductase activity
-2.70   PHYHIPL    NM_032439   Phytanoyl-CoA hydroxylase-interacting protein-like;PHYHIPL;ortholog
4.36    PI15       NM_015886   Peptidase inhibitor 15;PI15;ortholog
2.95    PICALM     NM_007166   Phosphatidylinositol-binding clathrin assembly protein;PICALM;ortholog
4.54    PIH1D1     NM_017916   PIH1 domain-containing protein 1;PIH1D1;ortholog
2.31    PILRB      NM_013440   Paired immunoglobulin-like type 2 receptor beta;PILRB;ortholog
-2.06   PIPPIN     NM_014460                                  RNA binding
                               Cold shock domain-containing protein C2;CSDC2;ortholog
2.66    PIR51      NM_006479   RAD51-associated protein 1;RAD51AP1;ortholog
-2.52   PKD2L1     NM_016112                                  ion channel activity
                               Polycystic kidney disease 2-like 1 protein;PKD2L1;ortholog
-2.16   PLA2G2D    NM_012400                                  phospholipase activity
                               Group IID secretory phospholipase A2;PLA2G2D;ortholog
-2.52   PLA2G6     NM_003560                                  phospholipase activity
                               85 kDa calcium-independent phospholipase A2;PLA2G6;ortholog
-2.27   PLA2R1     NM_007366                                  receptor activity
                               Soluble secretory phospholipase A2 receptor;PLA2R1;ortholog
-2.15   PLAC3      NM_020318   Pappalysin-2;PAPPA2;ortholog   metallopeptidase activity
3.26    PLDN       NM_012388   Pallidin;PLDN;ortholog
-2.39   PLEKHF2    NM_024613                                  transcription factor activity;transcription facto
                               Pleckstrin homology domain-containing family F member 2;PLEKHF2;orth
7.10    PLEKHG3    XM_085127   Pleckstrin homology domain-containing family G member 3;PLEKHG3;orth
3.20    PLEKHG4    XM_290684   Puratrophin-1;PLEKHG4;ortholog protein binding;small GTPase regulator activ
2.66    PLEKHJ1    NM_018049                                  protein binding;small GTPase regulator activ
                               Pleckstrin homology domain-containing family J member 1;PLEKHJ1;ortho
-2.70   PLSCR2     NM_020359   Phospholipid scramblase 2;PLSCR2;ortholog
2.40    PLTP       NM_006227   Phospholipid transfer protein;PLTP;ortholog
2.40    PMAIP1     NM_021127   Phorbol-12-myristate-13-acetate-induced protein 1;PMAIP1;ortholog
-3.13   PMS2       NM_000535                                  DNA binding
                               Mismatch repair endonuclease PMS2;PMS2;ortholog
2.38    PNPLA2     NM_020376                                  acyltransferase protein 2;PNPLA2;ortholog
                               Patatin-like phospholipase domain-containing activity;phospholipase activi
3.74    PNPO       NM_018129                                  oxidoreductase activity
                               Pyridoxine-5'-phosphate oxidase;PNPO;ortholog
2.87    POLA       NM_016937                                  DNA-directed DNA polymerase activity;exod
                               DNA polymerase alpha catalytic subunit;POLA1;ortholog
4.96    POLE3      NM_017443                                   DNA-directed DNA polymerase activity;trans
                               DNA polymerase epsilon subunit 3;POLE3;ortholog
3.89    POLE4      NM_019896                                   DNA-directed DNA polymerase activity;trans
                               DNA polymerase epsilon subunit 4;POLE4;ortholog
2.45    POLR1B     NM_019014                                   DNA-directed RNA polymerase activity;nucle
                               DNA-directed RNA polymerase I subunit RPA2;POLR1B;ortholog
3.50    POLR2J4    XM_379817   polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene (POLR2J
-2.81   POM121L1   NM_014348   POM121-like protein 1;POM121L1;ortholog
-2.52   POM121L12 NM_182595    POM121-like protein DKFZp564N2472;YG052_HUMAN;ortholog
2.73    POSTN      NM_006475   Periostin;POSTN;ortholog        receptor binding
-1.97   POU5F1     NM_002701                                   transcription factor activity;transcription facto
                               POU domain, class 5, transcription factor 1;POU5F1;ortholog
-2.13   PPEF1      NM_006240                                   phosphoprotein phosphatase activity;phosph
                               Serine/threonine-protein phosphatase with EF-hands 1;PPEF1;ortholog
3.36    PPFIA2     NM_003625   Liprin-alpha-2;PPFIA2;ortholog
-2.68   PPP1CA     NM_002708                                   phosphoprotein phosphatase activity;phosph
                               Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;PPP1C
2.58    PPP1R11    NM_021959   Protein phosphatase 1 regulatory subunit 11;PPP1R11;ortholog
3.43    PPP1R15A NM_014330     Protein phosphatase 1 regulatory subunit 15A;PPP1R15A;ortholog
3.15    PPP1R1A    NM_006741                                   receptor binding;phosphatase inhibitor activi
                               Protein phosphatase 1 regulatory subunit 1A;PPP1R1A;ortholog
4.33    PPP1R7     NM_002712                                   structural constituent of cytoskeleton;protein
                               Protein phosphatase 1 regulatory subunit 7;PPP1R7;ortholog
3.72    PPP2R5A    NM_006243                                   phosphoprotein phosphatase subunit alpha
                               Serine/threonine-protein phosphatase 2A 56 kDa regulatoryactivity;phosph
5.74    PPP3R2     NM_147180                                   phosphoprotein phosphatase activity;phosph
                               Calcineurin subunit B type 2;PPP3R2;ortholog
-2.79   PPT2       NM_005155                                   hydrolase activity,
                               Lysosomal thioesterase PPT2;PPT2;ortholog acting on ester bonds
2.65    PQLC2      NM_017765   PQ-loop repeat-containing protein 2;PQLC2;ortholog
-2.67   PRCC       NM_005973   Proline-rich protein PRCC;PRCC;ortholog
2.86    PRDM11     NM_020229   PR domain-containing protein 11;PRDM11;ortholog
3.63    PRDM2      NM_012231                                    2;PRDM2;ortholog
                               PR domain zinc finger protein transcription factor activity;transcription facto
2.32    PREB       NM_013388                                   DNA binding
                               Prolactin regulatory element-binding protein;PREB;ortholog
-2.51   PRG-3      NM_017753   Lipid phosphate phosphatase-related protein type 1;LPPR1;ortholog
-2.70   PRKAB1     NM_006253                                   protein binding;kinase regulator activity
                               5'-AMP-activated protein kinase subunit beta-1;PRKAB1;ortholog
11.69   PRKCI      NM_002740                                   protein kinase
                               Protein kinase C iota type;PRKCI;ortholog activity;calcium ion binding;ca
9.19    PRKG1      NM_006258                                   protein kinase activity
                               cGMP-dependent protein kinase 1, beta isozyme;PRKG1;ortholog
-2.67   PRND       NM_012409   Prion-like protein doppel;PRND;ortholog
-3.09   PRR14      NM_024031   Proline-rich protein 14;PRR14;ortholog
-2.01   PRRX2      NM_016307                                   transcription factor activity;transcription facto
                               Paired mesoderm homeobox protein 2;PRRX2;ortholog
3.95    PRX        NM_181882   Periaxin;PRX;ortholog
3.34    PSAP       NM_002778   Saposin-D;PSAP;ortholog         protein binding;enzyme regulator activity
-2.15   PTP4A1     NM_003463                                    type IVA 1;PTP4A1;ortholog
                               Protein tyrosine phosphatase phosphoprotein phosphatase activity;phosph
3.26    PTPN23     NM_015466                                    non-receptor type 23;PTPN23;ortholog
                               Tyrosine-protein phosphatase phosphoprotein phosphatase activity;phosph
-2.59   PTPRA      NM_002836                                   phosphoprotein phosphatase activity;phosph
                               Receptor-type tyrosine-protein phosphatase alpha;PTPRA;ortholog
-2.63   PTPRC      NM_002838                                   phosphoprotein
                               Leukocyte common antigen;PTPRC;ortholog phosphatase activity;phosph
-3.14   PTPRN2     NM_002847                                   phosphoprotein phosphatase activity;phosph
                               Receptor-type tyrosine-protein phosphatase N2;PTPRN2;ortholog
-2.29   PTPRU      NM_005704                                   phosphoprotein phosphatase activity;phosph
                               Receptor-type tyrosine-protein phosphatase U;PTPRU;ortholog
2.61    PTTG1      NM_004219   Securin;PTTG1;ortholog          transcription factor activity;transcription facto
2.16    PURA       NM_005859                                   single-stranded DNA binding;transcription fa
                               Transcriptional activator protein Pur-alpha;PURA;ortholog
-2.30   PUS1       NM_025215                                     A;PUS1;ortholog
                               tRNA pseudouridine synthaselyase activity
2.97    PVRL3      NM_015480                                   receptor activity
                               Poliovirus receptor-related protein 3;PVRL3;ortholog
3.83    PXDN,PRG2,MG50
                   XM_056455                                   oxidoreductase activity;peroxidase activity
                               Peroxidasin homolog;PXDN;ortholog
3.09    QPCTL      NM_017659                                   transferase activity
                               Glutaminyl-peptide cyclotransferase-like protein;QPCTL;ortholog
4.95    QRSL1      NM_018292                                   transferase activity;hydrolase activity;ligase
                               Glutamyl-tRNA(Gln) amidotransferase subunit A homolog;QRSL1;ortholog
-2.50   RAB21      NM_014999                                   GTPase activity;protein binding
                               Ras-related protein Rab-21;RAB21;ortholog
2.84    RAB3IL1    NM_013401                                     factor binding;small GTPase regulator activ
                               Guanine nucleotide exchangeprotein for Rab3A;RAB3IL1;ortholog
-3.29   RAB5A      NM_004162                                   GTPase activity;protein binding
                               Ras-related protein Rab-5A;RAB5A;ortholog
2.54    RAB6B      NM_016577                                   GTPase activity;protein binding
                               Ras-related protein Rab-6B;RAB6B;ortholog
-3.48   RAB7A      NM_004637                                   GTPase activity;protein binding
                               Ras-related protein Rab-7a;RAB7A;ortholog
3.05    RAB7B      NM_177403                                   GTPase activity;protein binding
                               Ras-related protein Rab-7b;RAB7B;ortholog
-2.28   RABIF      NM_002871                                     factor binding;small GTPase
                               Guanine nucleotide exchangeprotein MSS4;RABIF;ortholog regulator activ
-3.08   RAC4       XM_210062 This record was removed as a result of standard genome annotation proce
-2.03   RAD54L2                                               DNA
                   NM_015106 Helicase ARIP4;RAD54L2;ortholog helicase activity;nucleic acid binding
1.99    RAD9A      NM_004584                                          RAD9A;RAD9A;ortholog
                               Cell cycle checkpoint control protein binding;kinase activator activity;kinas
4.83    RAG1                                                  endodeoxyribonuclease activity;nucleic acid
                   NM_000448 V(D)J recombination-activating protein 1;RAG1;ortholog
2.24    RAI14      NM_015577 Ankycorbin;RAI14;ortholog
2.97    RAMP                                                  serine-type peptidase activity
                   NM_015430 Inactive serine protease RAMP;RAMP;ortholog
2.21    RAMP3                                                 receptor activity
                   NM_005856 Receptor activity-modifying protein 3;RAMP3;ortholog
-3.31   RANBP10                                               transmembrane transporter activity
                   NM_020850 Ran-binding protein 10;RANBP10;ortholog
-2.13   RAP1GAP    NM_002885                                  protein binding;small GTPase regulator activ
                               Rap1 GTPase-activating protein 1;RAP1GAP;ortholog
-2.30   RAPGEF1                                               protein binding;small GTPase regulator activ
                   NM_005312 Rap guanine nucleotide exchange factor 1;RAPGEF1;ortholog
2.74    RAPGEFL1                                              protein binding;small GTPase regulator
                   NM_016339 Rap guanine nucleotide exchange factor-like 1;RAPGEFL1;ortholog activ
3.80    RASGRP1    NM_005739                                  1;RASGRP1;ortholog
                               RAS guanyl-releasing protein protein binding;small GTPase regulator activ
3.59    RBAK       NM_021163                                  transcription factor activity;transcription facto
                               RB-associated KRAB zinc finger protein;RBAK;ortholog
-2.73   RBBP6                                                 nuclease activity;nucleic acid binding
                   NM_006910 Retinoblastoma-binding protein 6;RBBP6;ortholog
3.13    RBM25                                                  25;RBM25;ortholog
                   XM_027330 Probable RNA-binding protein RNA binding
4.23    RBM28      NM_018077                                  RNA binding
                               RNA-binding protein 28;RBM28;ortholog
2.57    RBMX2                                                 RNA 2;RBMX2;ortholog
                   NM_016024 RNA-binding motif protein, X-linked binding
-2.34   RCAN1      NM_004414 Calcipressin-1;RCAN1;ortholog    receptor binding
3.28    RCC2       NM_018715   Protein RCC2;RCC2;ortholog
-2.00   RCN3       NM_020650 Reticulocalbin-3;RCN3;ortholog   calcium ion binding;calmodulin binding
3.29    RCOR1      NM_015156 REST corepressor 1;RCOR1;orthologDNA binding
3.35    RCOR3      NM_018254 REST corepressor 3;RCOR3;orthologDNA binding
3.05    RDH11      NM_016026                                  oxidoreductase
                               Retinol dehydrogenase 11;RDH11;ortholog activity
3.04    REP15      XM_370686 Rab15 effector protein;REP15;ortholog
2.21    RESP18     XM_371593 Triskadecapeptide;RESP18;ortholog
2.94    RETN       NM_020415 Resistin;RETN;ortholog
4.12    RFC4                                                  DNA-directed DNA polymerase activity;nucle
                   NM_002916 Replication factor C subunit 4;RFC4;ortholog
3.17    RFPL4A     XM_292796 Ret finger protein-like 4A;RFPL4A;ortholog
4.77    RFX5                                                  nuclease activity;transcription factor activity;
                   NM_000449 DNA-binding protein RFX5;RFX5;ortholog
2.18    RGAG4      XM_291322 Retrotransposon gag domain-containing protein 4;Rgag4;ortholog
-3.16   RGL4                                                  protein binding;small GTPase regulator activ
                   NM_153615 Ral-GDS-related protein;RGL4;ortholog
4.28    RGMA       NM_020211 Repulsive guidance molecule A;RGMA;ortholog
-1.97   RGNEF                  Rho-guanine nucleotide exchange factor;RGNEF;ortholog
                   XM_371755, NM_001080479
3.59    RGS8                                                  protein binding;small
                   NM_033345 Regulator of G-protein signaling 8;RGS8;ortholog GTPase regulator activ
2.59    RHBG                                                  cation transmembrane
                   NM_020407 Ammonium transporter Rh type B;RHBG;ortholog transporter activity
2.34    RHCE       NM_020485                                  cation transmembrane transporter activity
                               Blood group Rh(CE) polypeptide;RHCE;ortholog
-2.50   RHOV       NM_133639                                  GTPase activity;protein
                               Rho-related GTP-binding protein RhoV;RHOV;orthologbinding
3.20    RHPN2      NM_033103 Rhophilin-2;RHPN2;ortholog
3.29    RIN1                                                  protein binding;small GTPase regulator activ
                   NM_004292 Ras and Rab interactor 1;RIN1;ortholog
2.29    RING1      NM_002931                                  transcription factor
                               E3 ubiquitin-protein ligase RING1;RING1;orthologactivity;transcription facto
-2.55   RIPK1                                                 protein kinase kinase
                   NM_003804 Receptor-interacting serine/threonine-protein activity 1;RIPK1;ortholog
-2.54   RIPX       NM_014961 Protein RUFY3;RUFY3;ortholog     transcription factor activity;transcription facto
3.15    RKHD2      NM_016626                                  ubiquitin-protein
                               RNA-binding protein MEX3C;MEX3C;ortholog ligase activity;RNA binding
3.84    RNF126     NM_017876 RING finger protein 126;RNF126;ortholog
2.75    RNF138                                                transcription factor activity;transcription facto
                   NM_016271 E3 ubiquitin-protein ligase RNF138;RNF138;ortholog
7.82    RNF14      NM_004290                                  ubiquitin-protein ligase
                               E3 ubiquitin-protein ligase RNF14;RNF14;ortholog activity;transcription f
-2.23   RNF151     XM_370927 RING finger protein 151;RNF151;ortholog
4.02    RNF2                                                  transcription factor
                   NM_007212 E3 ubiquitin-protein ligase RING2;RNF2;ortholog activity;transcription facto
-3.29   RNF25                                                 transcription factor activity;transcription facto
                   NM_022453 E3 ubiquitin-protein ligase RNF25;RNF25;ortholog
-2.17   RNF26      NM_032015                                  ubiquitin-protein ligase activity
                               RING finger protein 26;RNF26;ortholog
-2.02   RNF30                                                 ubiquitin-protein ligase
                   NM_032546 Tripartite motif-containing protein 54;TRIM54;orthologactivity
-2.98   RNF32      NM_030936 RING finger protein 32;RNF32;ortholog
5.24    RNF38       NM_022781   RING finger protein 38;RNF38;ortholog
2.32    RNF44       NM_014901   RING finger protein 44;RNF44;ortholog
11.91   RP2         NM_006915   Protein XRP2;RP2;ortholog nucleotide kinase activity
2.06    RPS6KB2     NM_003952                                    protein kinase activity
                                Ribosomal protein S6 kinase beta-2;RPS6KB2;ortholog
2.29    RPS6KB2     NM_003952                                    protein kinase activity
                                Ribosomal protein S6 kinase beta-2;RPS6KB2;ortholog
3.12    RS1         NM_000330   Retinoschisin;RS1;ortholog metallopeptidase activity;serine-type peptida
-2.30   RTN4        NM_007008   Reticulon-4;RTN4;ortholog
2.36    RTN4RL1     NM_178568                                    receptor activity
                                Reticulon-4 receptor-like 1;RTN4RL1;ortholog
2.47    RUTBC3      NM_015705                                    protein binding;small GTPase regulator activ
                                Small G protein signaling modulator 3;SGSM3;ortholog
5.20    RUVBL2      NM_006666   RuvB-like 2;RUVBL2;ortholog DNA helicase activity;transcription factor act
-2.50   RYR2        NM_001035                                    receptor
                                Ryanodine receptor 2;RYR2;ortholog activity;ligand-gated ion channel ac
2.91    SAPS3       NM_018312                                    protein 6 regulatory subunit 3;SAPS3;ortho
                                Serine/threonine-protein phosphatasebinding;phosphatase regulator activit
3.16    SARA1       NM_020150                                    GTPase activity;protein binding
                                GTP-binding protein SAR1a;SAR1A;ortholog
2.30    SARG        NM_023938   Specifically androgen-regulated gene protein;SARG;ortholog
4.36    SASH1       NM_015278   SAM and SH3 domain-containing protein 1;SASH1;ortholog
-2.63   SCAMP4      NM_079834                                    transferase activity
                                Secretory carrier-associated membrane protein 4;SCAMP4;ortholog
3.09    SCAP2       NM_003930   Src kinase-associated phosphoprotein 2;SKAP2;ortholog
3.46    SCHIP1      NM_014575   Schwannomin-interacting protein 1;SCHIP1;ortholog
-2.12   SCNN1B      NM_000336                                    ion channel activity
                                Amiloride-sensitive sodium channel subunit beta;SCNN1B;ortholog
2.69    SCP2        NM_002979                                    oxidoreductase activity
                                Non-specific lipid-transfer protein;SCP2;ortholog
-2.97   SCRT2       NM_033129                                    transcription factor activity;transcription facto
                                Transcriptional repressor scratch 2;SCRT2;ortholog
2.51    SCUBE1      NM_173050   Signal peptide, CUB and EGF-like domain-containing protein 1;SCUBE1;o
-2.09   SDPR        NM_004657                                    transcription factor activity;transcription facto
                                Serum deprivation-response protein;SDPR;ortholog
2.60    SEC22B      NM_004892                                    SNAP receptor activity
                                Vesicle-trafficking protein SEC22b;SEC22B;ortholog
3.15    SEMA3A      NM_006080   Semaphorin-3A;SEMA3A;ortholog    receptor binding
-2.38   SEMA4D      NM_006378   Semaphorin-4D;SEMA4D;ortholog    receptor binding
3.65    SEMA5B      NM_018987   Semaphorin-5B;SEMA5B;ortholog    receptor binding
6.58    SERF1B      NM_022978   Small EDRK-rich factor 1;SERF1B;ortholog
2.18    SERHL2      NM_014509                                    serine-type peptidase
                                Serine hydrolase-like protein 2;SERHL2;ortholog activity
-2.17   SERPINB12   NM_080474   Serpin B12;SERPINB12;ortholog    protein binding;serine-type endopeptidase in
2.55    SERPINC1    NM_000488                                    protein
                                Antithrombin-III;SERPINC1;ortholog binding;serine-type endopeptidase in
4.16    SERPIND1    NM_000185                                    protein binding;serine-type endopeptidase in
                                Heparin cofactor 2;SERPIND1;ortholog
-2.24   SERPINE2    NM_006216                                    protein binding;serine-type endopeptidase in
                                Glia-derived nexin;SERPINE2;ortholog
-2.74   SERPINH1    NM_001235   Serpin H1;SERPINH1;ortholog      protein binding;serine-type endopeptidase in
-3.46   SERPINI1    NM_005025   Neuroserpin;SERPINI1;ortholog    protein binding;serine-type endopeptidase in
-3.08   SERTAD2     XM_376059                                    transcription factor activity;transcription facto
                                SERTA domain-containing protein 2;SERTAD2;ortholog
3.15    SERTAD4     NM_019605   SERTA domain-containing protein 4;SERTAD4;ortholog
2.92    SFRP1       NM_003012                                    receptor binding
                                Secreted frizzled-related protein 1;SFRP1;ortholog
2.16    SFRS11      NM_004768   Splicing factor, arginine/serine-rich 11;SFRS11;ortholog
2.75    SFRS2       NM_003016                                    RNA 2;SFRS2;ortholog
                                Splicing factor, arginine/serine-rich splicing factor activity, transesterificatio
3.28    SFRS4       NM_005626                                    RNA 4;SFRS4;ortholog
                                Splicing factor, arginine/serine-rich splicing factor activity, transesterificatio
3.22    SGK494      NM_144610                                    protein kinase activity
                                Uncharacterized serine/threonine-protein kinase SgK494;SGK494;ortholog
-2.72   SH2D1A      NM_002351   SH2 domain-containing protein 1A;SH2D1A;ortholog
10.41   SH3KBP1     NM_031892                                    receptor protein
                                SH3 domain-containing kinase-binding binding 1;SH3KBP1;ortholog
3.69    SHAX3       NM_152284   Charged multivesicular body protein 4c;CHMP4C;ortholog
-2.53   SHB         NM_003028   SH2 domain-containing adapter protein B;SHB;ortholog
-2.99   SHBG        NM_001040   Sex hormone-binding globulin;SHBG;ortholog
-3.59   SHF         XM_032304   SH2 domain-containing adapter protein F;SHF;ortholog
2.95    SHFM3       NM_022039   F-box/WD repeat-containing protein 4;FBXW4;ortholog
-2.20   SHREW1      NM_018836   Adherens junction-associated protein 1;AJAP1;ortholog
2.23    SIAH1       NM_003031                                    ubiquitin-protein ligase activity
                                E3 ubiquitin-protein ligase SIAH1;SIAH1;ortholog
-2.07   SIGLEC10    NM_033130                                    receptor activity;receptor
                                Sialic acid-binding Ig-like lectin 10;SIGLEC10;ortholog binding
3.34    SIGLEC11   NM_052884                                    receptor activity;receptor
                               Sialic acid-binding Ig-like lectin 11;SIGLEC11;ortholog binding
4.17    SIN3A      NM_015477                                    deacetylase activity;transcription factor activ
                               Paired amphipathic helix protein Sin3a;SIN3A;ortholog
4.27    SIPA1      NM_006747                                    protein binding;small GTPase regulator activ
                               Signal-induced proliferation-associated protein 1;SIPA1;ortholog
-2.25   SIRT2      NM_012237                                    deacetylase activity;nucleic acid binding;chr
                               NAD-dependent deacetylase sirtuin-2;SIRT2;ortholog
-2.15   SLC13A3    NM_022829                                    cation transmembrane
                               Solute carrier family 13 member 3;SLC13A3;orthologtransporter activity
-2.35   SLC25A21   NM_030631   Mitochondrial 2-oxodicarboxylate carrier;SLC25A21;ortholog
-2.94   SLC26A8    NM_052961                                    transmembrane
                               Testis anion transporter 1;SLC26A8;ortholog transporter activity
-2.47   SLC26A9    NM_052934                                    transmembrane transporter activity
                               Solute carrier family 26 member 9;SLC26A9;ortholog
2.51    SLC2A3     NM_006931                                    carbohydrate transmembrane transporter ac
                               Solute carrier family 2, facilitated glucose transporter member 3;SLC2A3;o
2.50    SLC2A8     NM_014580                                    carbohydrate transmembrane transporter ac
                               Solute carrier family 2, facilitated glucose transporter member 8;SLC2A8;o
3.76    SLC35C1    NM_018389                                    transmembrane
                               GDP-fucose transporter 1;SLC35C1;ortholog transporter activity
3.47    SLC35C2    NM_015945                                    transmembrane transporter
                               Solute carrier family 35 member C2;SLC35C2;ortholog activity
-2.27   SLC36A1    NM_078483   Proton-coupled amino acid transporter 1;SLC36A1;ortholog
2.05    SLC37A1    NM_018964                                    transmembrane transporter activity
                               Glycerol-3-phosphate transporter;SLC37A1;ortholog
3.09    SLC38A8    XM_085347   Putative sodium-coupled neutral amino acid transporter 8;SLC38A8;ortholo
2.88    SLC39A14   NM_015359                                    transmembrane transporter activity
                               Zinc transporter ZIP14;SLC39A14;ortholog
-2.28   SLC39A2    NM_014579                                    transmembrane transporter activity
                               Zinc transporter ZIP2;SLC39A2;ortholog
-2.83   SLC39A4    NM_017767                                    transmembrane transporter activity
                               Zinc transporter ZIP4;SLC39A4;ortholog
6.03    SLC43A1    NM_003627   Large neutral amino acids transporter small subunit 3;SLC43A1;ortholog
2.99    SLC4A1     NM_000342                                    transmembrane transporter activity
                               Band 3 anion transport protein;SLC4A1;ortholog
-3.25   SLC4A4     NM_003759                                    cation transmembrane transporter activity
                               Electrogenic sodium bicarbonate cotransporter 1;SLC4A4;ortholog
3.01    SLC5A1     NM_000343                                      1;SLC5A1;ortholog
                               Sodium/glucose cotransportercarbohydrate transmembrane transporter ac
3.10    SLC6A20    NM_020208                                    amino acid transmembrane transporter activ
                               Sodium- and chloride-dependent transporter XTRP3;SLC6A20;ortholog
4.80    SLC7A11    NM_014331                                    amino acid transmembrane transporter activ
                               Cystine/glutamate transporter;SLC7A11;ortholog
-1.99   SLC7A7     NM_003982                                    amino acid transmembrane transporter activ
                               Y+L amino acid transporter 1;SLC7A7;ortholog
3.97    SLC9A3     NM_004174                                    cation transmembrane transporter activity
                               Sodium/hydrogen exchanger 3;SLC9A3;ortholog
2.17    SLC9A7     NM_032591                                    cation transmembrane transporter activity
                               Sodium/hydrogen exchanger 7;SLC9A7;ortholog
-2.08   SLITRK2    NM_032539                                    receptor activity
                               SLIT and NTRK-like protein 2;SLITRK2;ortholog
-2.28   SMAP-1     NM_018671   Protein unc-45 homolog A;UNC45A;ortholog
-2.10   SMARCA4    NM_003072                                    DNA helicase activity;nucleic acid binding
                               Probable global transcription activator SNF2L4;SMARCA4;ortholog
2.35    SMARCAL1   NM_014140                                    DNA helicase activity;nucleic acid chromatin
                               SWI/SNF-related matrix-associated actin-dependent regulator of binding
2.67    SMARCD1    NM_003076                                    nucleic acid binding;chromatin binding
                               SWI/SNF-related matrix-associated actin-dependent regulator of chromatin
-2.26   SMEK1      NM_032560   Serine/threonine-protein phosphatase 4 regulatory subunit 3A;SMEK1;orth
3.67    SMOX       NM_019025   Spermine oxidase;SMOX;ortholog   oxidoreductase activity;nucleic acid binding
3.04    SMP1       NM_014313   Transmembrane protein 50A;TMEM50A;ortholog
1.99    SMPD4      NM_017751   Sphingomyelin phosphodiesterase 4;SMPD4;ortholog
-2.39   SNAI2      NM_003068                                    transcription
                               Zinc finger protein SNAI2;SNAI2;ortholog factor activity;transcription facto
3.75    SNX12      NM_013346   Sorting nexin-12;SNX12;ortholog
-3.68   SNX9       NM_016224   Sorting nexin-9;SNX9;ortholog
2.86    SOST       NM_025237   Sclerostin;SOST;ortholog         receptor binding
-2.27   SP4        NM_003112                                    transcription factor activity;transcription facto
                               Transcription factor Sp4;SP4;ortholog
-2.51   SPATA7     NM_018418   Spermatogenesis-associated protein 7;SPATA7;ortholog
2.11    SPC18      NM_014300                                    serine-type peptidase activity
                               Signal peptidase complex catalytic subunit SEC11A;SEC11A;ortholog
2.96    SPC25      NM_020675   Kinetochore protein Spc25;SPC25;ortholog
-3.43   SPDYC      XM_370631   Speedy protein C;SPDYC;ortholog
2.95    SPG4       NM_014946   Spastin;SPAST;ortholog           hydrolase activity;structural constituent of cy
2.65    SPIN       NM_006717   Spindlin-1;SPIN1;ortholog
-2.06   SPINK5     NM_006846                                    protein binding
                               Hemofiltrate peptide HF7665;SPINK5;ortholog
-2.32   SPINT2     NM_021102                                     2;SPINT2;ortholog
                               Kunitz-type protease inhibitor protein binding;serine-type endopeptidase in
-2.06   SPOCD1     NM_144569   SPOC domain-containing protein 1;SPOCD1;ortholog
2.53    SPOCK3     NM_016950   Testican-3;SPOCK3;ortholog calcium ion binding;protein binding;cysteine-
-2.13   SPRY4      NM_030964                                    transcription factor activity;receptor binding;t
                               Protein sprouty homolog 4;SPRY4;ortholog
-2.50   SRCRB4D   NM_080744                                    receptor activity
                              Scavenger receptor cysteine-rich domain-containing group B protein;SRCR
3.03    SRPUL     NM_014467   Sushi repeat-containing protein SRPX2;SRPX2;ortholog
-2.03   SSB3      NM_080861   SPRY domain-containing SOCS box protein 3;SPSB3;ortholog
-2.20   SSR1      NM_003144                                      subunit alpha;SSR1;ortholog
                              Translocon-associated proteincalcium ion binding
2.26    SSX1      NM_005635   Protein SSX1;SSX1;ortholog transcription factor activity;transcription facto
2.83    STAP2     NM_017720                                    transmembrane receptor
                              Signal-transducing adaptor protein 2;STAP2;ortholog protein kinase activ
-2.21   STAT1     NM_007315                                    transcription factor activity;transcription facto
                              Signal transducer and activator of transcription 1-alpha/beta;STAT1;ortholo
4.29    STEAP     NM_012449   Metalloreductase STEAP1;STEAP1;ortholog
-2.54   STEAP1B   NM_207342   STEAP family protein MGC87042;STEAL_HUMAN;ortholog
-1.96   STK32B    NM_018401                                    protein kinase activity
                              Serine/threonine-protein kinase 32B;STK32B;ortholog
2.82    STK4      NM_006282                                    protein kinase activity
                              Serine/threonine-protein kinase 4;STK4;ortholog
-2.55   STMN1     NM_005563   Stathmin;STMN1;ortholog
5.40    STOML2    NM_013442                                    structural constituent of cytoskeleton
                              Stomatin-like protein 2;STOML2;ortholog
2.91    STOX2     XM_048721   Storkhead-box protein 2;STOX2;ortholog
2.26    STX12     NM_177424   Syntaxin-12;STX12;ortholog SNAP receptor activity
4.89    STX17     NM_017919   Syntaxin-17;STX17;ortholog SNAP receptor activity
2.54    STX3A     NM_004177   Syntaxin-3;STX3;ortholog         SNAP receptor activity
2.50    STYX      NM_145251                                    phosphoprotein phosphatase
                              Serine/threonine/tyrosine-interacting protein;STYX;ortholog activity;phosph
-3.45   STYXL1    NM_016086                                    phosphoprotein phosphatase activity;phosph
                              Serine/threonine/tyrosine-interacting-like protein 1;STYXL1;ortholog
-2.29   SUB1      NM_006713                                    transcription factor activity;transcription facto
                              Activated RNA polymerase II transcriptional coactivator p15;SUB1;ortholog
2.01    SULF1     NM_015170                                    hydrolase activity
                              Extracellular sulfatase Sulf-1;SULF1;ortholog
4.45    SUPT3H    NM_003599                                     SPT3 homolog;SUPT3H;ortholog
                              Transcription initiation protein transcription factor activity;transcription facto
3.57    SURB7     NM_004264                                    transcription factor activity;transcription facto
                              Mediator of RNA polymerase II transcription subunit 21;MED21;ortholog
2.69    SUV39H1   NM_003173                                    methyltransferase activity;DNA binding
                              Histone-lysine N-methyltransferase SUV39H1;SUV39H1;ortholog
-2.36   SVOP      NM_018711                                    carbohydrate transmembrane transporter ac
                              Synaptic vesicle 2-related protein;SVOP;ortholog
-3.13   SYMPK     NM_004819   Symplekin;SYMPK;ortholog
-2.21   SYNCRIP   NM_006372                                    structural constituent of ribosome;mRNA bin
                              Heterogeneous nuclear ribonucleoprotein Q;SYNCRIP;ortholog
2.62    SYP       NM_003179   Synaptophysin;SYP;ortholog
-2.98   TACSTD2   NM_002353                                    receptor activity
                              Tumor-associated calcium signal transducer 2;TACSTD2;ortholog
2.62    TAF1B     NM_005680   TATA box-binding protein-associated factor RNA polymerase I subunit B;T
-2.64   TAS2R42   NM_181429   Taste receptor type 2 member 42;TAS2R42;ortholog
2.57    TBR1      NM_006593                                    transcription factor activity;transcription facto
                              T-box brain protein 1;TBR1;ortholog
-3.31   TCEAL1    NM_004780                                      A protein-like 1;TCEAL1;ortholog
                              Transcription elongation factortranscription factor activity;transcription facto
4.56    TCEB1     NM_005648                                      B polypeptide 1;TCEB1;ortholog
                              Transcription elongation factorenzyme activator activity
2.52    TCEB2     NM_007108                                      B polypeptide 2;TCEB2;ortholog
                              Transcription elongation factortranscription factor activity;transcription facto
3.48    TCEB3B    NM_016427                                    transcription factor activity;transcription facto
                              RNA polymerase II transcription factor SIII subunit A2;TCEB3B;ortholog
4.66    TCF19     NM_007109   Transcription factor 19;TCF19;ortholog
-2.42   TDRD1     NM_198795                                    nuclease activity;nucleic acid binding
                              Tudor domain-containing protein 1;TDRD1;ortholog
-2.48   TDRD3     NM_030794   Tudor domain-containing protein 3;TDRD3;ortholog
2.54    TEAD4     NM_003213                                    transcription factor activity;transcription facto
                              Transcriptional enhancer factor TEF-3;TEAD4;ortholog
-2.16   TEDDM1    NM_172000   Transmembrane epididymal protein 1;TEDDM1;ortholog
3.57    TEGT      NM_003217   Bax inhibitor 1;TMBIM6;ortholog
-2.94   TENC1     NM_015319                                    structural constituent of cytoskeleton;actin b
                              Tensin-like C1 domain-containing phosphatase;TENC1;ortholog
2.61    TENS1     NM_022748   Tensin-3;TNS3;ortholog           phosphoprotein phosphatase activity;phosph
2.65    TERF2IP   NM_018975                                    nucleic acid binding
                              Telomeric repeat-binding factor 2-interacting protein 1;TERF2IP;ortholog
-2.04   TESK1     NM_006285                                     protein kinase 1;TESK1;ortholog
                              Dual specificity testis-specificprotein kinase activity
2.44    TEX11     NM_031276   Testis-expressed sequence 11 protein;TEX11;ortholog
-2.74   TF        NM_001063   Serotransferrin;TF;ortholog serine-type peptidase activity
2.42    TFDP1     NM_007111                                    transcription
                              Transcription factor Dp-1;TFDP1;ortholog factor activity;transcription facto
-2.57   TFG       NM_006070   Protein TFG;TFG;ortholog
3.60    TGFB2     NM_003238                                    growth factor activity
                              Transforming growth factor beta-2;TGFB2;ortholog
-2.70   TGM1      NM_000359                                    acyltransferase K;TGM1;ortholog
                              Protein-glutamine gamma-glutamyltransferaseactivity
3.95    TGM6        NM_198994                                   acyltransferase 6;TGM6;ortholog
                                Protein-glutamine gamma-glutamyltransferaseactivity
-2.13   THAP3       NM_138350                                   nucleic acid binding
                                THAP domain-containing protein 3;THAP3;ortholog
-2.67   THRA        NM_003250                                   ligand-dependent
                                Thyroid hormone receptor alpha;THRA;ortholog nuclear receptor activity;tra
2.64    THRAP2      NM_015335   Mediator of RNA polymerase II transcription subunit 13-like;MED13L;ortho
-2.43   THRAP3      NM_005119                                   receptor activity;transcription factor
                                Thyroid hormone receptor-associated protein 3;THRAP3;ortholog activity;D
7.69    THRAP4      NM_014815                                   receptor activity
                                Mediator of RNA polymerase II transcription subunit 24;MED24;ortholog
4.15    THSD1       NM_018676   Thrombospondin type-1 domain-containing protein 1;THSD1;ortholog
-2.98   TIPARP      NM_015508                                   nucleic acid binding
                                TCDD-inducible poly [ADP-ribose] polymerase;TIPARP;ortholog
-2.48   TITF1       NM_003317                                   transcription factor activity;transcription facto
                                Homeobox protein Nkx-2.1;NKX2-1;ortholog
2.99    TJP3        NM_014428   Tight junction protein ZO-3;TJP3;ortholog
4.17    TK2         NM_004614                                   nucleotide kinase
                                Thymidine kinase 2, mitochondrial;TK2;ortholog activity
-2.58   TKTL1       NM_012253                                   transketolase
                                Transketolase-like protein 1;TKTL1;ortholog activity
-2.50   TKTL2       NM_032136                                   transketolase
                                Transketolase-like protein 2;TKTL2;ortholog activity
2.47    TLE4        NM_007005                                   transcription factor
                                Transducin-like enhancer protein 4;TLE4;orthologactivity;transcription facto
-2.45   TLL1        NM_012464                                   oxidoreductase activity;serine-type peptidas
                                Tolloid-like protein 1;TLL1;ortholog
-2.33   TLR9        NM_017442                                   receptor activity
                                Toll-like receptor 9;TLR9;ortholog
-2.15   TLX3        NM_021025                                   transcription factor activity;transcription facto
                                T-cell leukemia homeobox protein 3;TLX3;ortholog
4.10    TM4SF1      NM_014220   Transmembrane 4 L6 family member 1;TM4SF1;ortholog
2.71    TMEM10      NM_033207   Opalin;OPALIN;ortholog
4.21    TMEM108     NM_023943   Transmembrane protein 108;TMEM108;ortholog
-2.12   TMEM134     NM_025124   Transmembrane protein 134;TMEM134;ortholog
-2.12   TMEM14B     NM_030969   Transmembrane protein 14B;TMEM14B;ortholog
3.02    TMEM16B     NM_020373   Anoctamin-2;ANO2;ortholog
-2.39   TMEM177     NM_030577   Transmembrane protein 177;TMEM177;ortholog
3.62    TMEM186     NM_015421   Transmembrane protein 186;TMEM186;ortholog
2.54    TMEM2       NM_013390   Transmembrane protein 2;TMEM2;ortholog
-2.52   TMEM33      NM_018126   Transmembrane protein 33;TMEM33;ortholog
2.53    TMEM35      NM_021637   Transmembrane protein 35;TMEM35;ortholog
3.58    TMEM85      NM_016454   Transmembrane protein 85;TMEM85;ortholog
3.45    TMPRSS2     NM_005656                                   serine-type peptidase activity
                                Transmembrane protease, serine 2 catalytic chain;TMPRSS2;ortholog
4.84    TMPRSS4     NM_019894                                   serine-type peptidase activity
                                Transmembrane protease, serine 4;TMPRSS4;ortholog
-2.42   TNA         NM_003278   Tetranectin;CLEC3B;ortholog extracellular matrix structural constituent
-2.90   TNFRSF10D   NM_003840                                   cytokine receptor activity;tumor necrosis fac
                                Tumor necrosis factor receptor superfamily member 10D;TNFRSF10D;orth
-2.47   TNFRSF17    NM_001192                                   cytokine receptor activity
                                Tumor necrosis factor receptor superfamily member 17;TNFRSF17;ortholo
-2.38   TNFRSF1A    NM_001065                                    protein 1;TNFRSF1A;ortholog
                                Tumor necrosis factor-binding cytokine receptor activity;tumor necrosis fac
-2.45   TNFRSF9     NM_001561                                   receptor activity
                                Tumor necrosis factor receptor superfamily member 9;TNFRSF9;ortholog
3.33    TNNI1       NM_003281                                   structural constituent of cytoskeleton;actin b
                                Troponin I, slow skeletal muscle;TNNI1;ortholog
-2.32   TNPO2       NM_013433   Transportin-2;TNPO2;orthologtransmembrane transporter activity
4.62    TOB2        NM_016272   Protein Tob2;TOB2;ortholog
-2.66   TOCA1       NM_017737                                   structural constituent of cytoskeleton;recept
                                Formin-binding protein 1-like;FNBP1L;ortholog
-2.44   TOE1        NM_025077   Target of EGR1 protein 1;TOE1;ortholog
-2.49   TOM1        NM_005488                                   transmembrane transporter activity
                                Target of Myb protein 1;TOM1;ortholog
3.70    TOMM7       NM_019059                                   subunit TOM7 homolog;TOMM7;ortholog
                                Mitochondrial import receptor transmembrane transporter activity
4.32    TOP1        NM_003286                                   DNA topoisomerase activity;DNA topoisome
                                DNA topoisomerase 1;TOP1;ortholog
3.74    TP53BP2     NM_005426                                   protein binding
                                Apoptosis-stimulating of p53 protein 2;TP53BP2;ortholog
-2.34   TP53I3      NM_004881                                   oxidoreductase activity
                                Putative quinone oxidoreductase;TP53I3;ortholog
3.11    TP53INP1    NM_033285   Tumor protein p53-inducible nuclear protein 1;TP53INP1;ortholog
-3.23   TP63        NM_003722   Tumor protein 63;TP63;ortholog  transcription factor activity;transcription facto
-2.35   TPD52L1     NM_003287   Tumor protein D53;TPD52L1;ortholog
3.27    TPD52L2     NM_003288   Tumor protein D54;TPD52L2;ortholog
3.75    TPK1        NM_022445                                   kinase activity
                                Thiamin pyrophosphokinase 1;TPK1;ortholog
-2.68   TPR         NM_003292   Nucleoprotein TPR;TPR;ortholog  transmembrane receptor protein kinase activ
-3.24   TPT1         NM_003295                                    structural constituent of
                                 Translationally-controlled tumor protein;TPT1;ortholog cytoskeleton;microt
2.70    TRAM2        NM_012288   Translocation-associated membrane protein 2;TRAM2;ortholog
-2.09   TRAPPC2L     NM_016209   Trafficking protein particle complex subunit 2-like protein;TRAPPC2L;ortho
-2.15   TRIM41       NM_033549                                    ubiquitin-protein ligase
                                 Tripartite motif-containing protein 41;TRIM41;orthologactivity
2.76    TRIM58       NM_015431                                    ubiquitin-protein ligase
                                 Tripartite motif-containing protein 58;TRIM58;orthologactivity
3.18    TRIM62       NM_018207                                    ubiquitin-protein ligase
                                 Tripartite motif-containing protein 62;TRIM62;orthologactivity
-2.14   TRIP10       NM_004240                                    structural constituent of cytoskeleton;recept
                                 Cdc42-interacting protein 4;TRIP10;ortholog
2.39    TRMT1        NM_018006                                    RNA methyltransferase activity;nucleic acid
                                 Mitochondrial tRNA-specific 2-thiouridylase 1;TRMU;ortholog
-2.42   TRPC3        NM_003305                                    ion           3;TRPC3;ortholog
                                 Short transient receptor potential channel activity
-2.20   TRPC5        NM_012471                                    ion           5;TRPC5;ortholog
                                 Short transient receptor potential channel activity
-2.26   TRPS1        NM_014112                                     Trps1;TRPS1;ortholog
                                 Zinc finger transcription factor nuclease activity;transcription factor activity;
2.83    TSARG6       NM_153614   DnaJ homolog subfamily B member 13;DNAJB13;ortholog
2.77    TSGA13       NM_052933   Testis-specific gene 13 protein;TSGA13;ortholog
-2.27   TSGA14       NM_018718   Centrosomal protein of 41 kDa;TSGA14;ortholog
2.37    TSPAN33      NM_178562   Tetraspanin-33;TSPAN33;ortholog  receptor binding
-2.32   TSPAN9       NM_031285   Tetraspanin-9;TSPAN9;ortholog    receptor binding
4.02    TSRC1        NM_019032   ADAMTS-like protein 4;ADAMTSL4;ortholog
2.22    TST          NM_003312                                    transferase
                                 Thiosulfate sulfurtransferase;TST;ortholog activity
2.39    TTC11        NM_016068   Mitochondrial fission 1 protein;FIS1;ortholog
3.52    TTC15        NM_016030                                    peptidase activity
                                 Tetratricopeptide repeat protein 15;TTC15;ortholog
2.35    TTC9         XM_027236                                    isomerase activity
                                 Tetratricopeptide repeat protein 9A;TTC9;ortholog
-2.41   TTID         NM_006790   Myotilin;MYOT;ortholog           structural constituent of cytoskeleton
-3.29   TTLL6        NM_173623                                    ligase activity;structural constituent of cytos
                                 Tubulin polyglutamylase TTLL6;TTLL6;ortholog
3.75    TUBA3        NM_006009                                    structural constituent of cytoskeleton
                                 Tubulin alpha-1A chain;TUBA1A;ortholog
-2.41   TUBA3E       NM_207312                                    structural constituent of cytoskeleton
                                 Tubulin alpha-3E chain;TUBA3E;ortholog
3.30    TUBG2        NM_016437                                    structural
                                 Tubulin gamma-2 chain;TUBG2;orthologconstituent of cytoskeleton
2.76    TULP1        NM_003322   Tubby-related protein 1;TULP1;ortholog
2.08    TUSC3        NM_006765                                    transferase activity,
                                 Tumor suppressor candidate 3;TUSC3;ortholog transferring glycosyl gro
-2.34   TWIST2       NM_057179                                    transcription
                                 Twist-related protein 2;TWIST2;ortholog factor activity;transcription facto
2.36    TYMS         NM_001071                                    methyltransferase activity
                                 Thymidylate synthase;TYMS;ortholog
8.33    UBCE7IP5     NM_014948   RING finger protein 37;UBOX5;ortholog
-2.35   UBE1DC1      NM_024818                                    ligase activity
                                 Ubiquitin-like modifier-activating enzyme 5;UBA5;ortholog
2.87    UBE1L        NM_003335                                    ligase activity
                                 Ubiquitin-like modifier-activating enzyme 7;UBA7;ortholog
-2.32   UBE2K        NM_005339                                     E2 K;UBE2K;ortholog
                                 Ubiquitin-conjugating enzyme ligase activity
2.53    UBE2R2       NM_017811                                     E2 R2;UBE2R2;ortholog
                                 Ubiquitin-conjugating enzyme ligase activity
-2.13   UBE3B        NM_130466                                    ubiquitin-protein
                                 Ubiquitin-protein ligase E3B;UBE3B;ortholog ligase activity
3.21    UBQLN1       NM_013438   Ubiquilin-1;UBQLN1;ortholog
-2.67   UBXN2B       XM_059929   UBX domain-containing protein 2B;UBXN2B;ortholog
2.89    UDPGT,UGT1   NM_007120                                    1-5;UGT1A5;ortholog
                                 UDP-glucuronosyltransferase transferase activity, transferring glycosyl gro
2.23    UFSP1        XM_380026   Inactive Ufm1-specific protease 1;UFSP1;ortholog
2.66    UGT1A5       NM_019078                                    1-5;UGT1A5;ortholog
                                 UDP-glucuronosyltransferase transferase activity, transferring glycosyl gro
5.90    UHRF1        NM_013282                                    transcription factor activity;transcription facto
                                 E3 ubiquitin-protein ligase UHRF1;UHRF1;ortholog
-2.44   UIMC1        NM_016290   Ubiquitin interaction motif-containing protein 1;UIMC1;ortholog
4.08    UMPS         NM_000373   Orotidine 5'-phosphate decarboxylase;UMPS;ortholog
2.59    UNC5C        NM_003728                                    receptor activity
                                 Netrin receptor UNC5C;UNC5C;ortholog
-2.39   UNG2         NM_021147   Cyclin-O;CCNO;ortholog           nucleic acid binding;protein binding;kinase a
2.69    UPK2         NM_006760   Uroplakin-2;UPK2;ortholog
3.72    UPP1         NM_003364                                    phosphorylase activity
                                 Uridine phosphorylase 1;UPP1;ortholog
-2.46   UPRT         NM_145052                                    nucleotide kinase
                                 Uracil phosphoribosyltransferase;UPRT;orthologactivity;transferase activity
2.78    UQCRB        NM_006294                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 7;UQCRB;ortholog
4.18    UQCRFS1      NM_006003                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 11;UQCRFS1;ortholog
4.93    UQCRH        NM_006004                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 6, mitochondrial;UQCRH;ortholog
2.27    USE1      NM_018467   Vesicle transport protein USE1;USE1;ortholog
5.51    USH3A     NM_052995   Clarin-1;CLRN1;ortholog
-2.94   USP1      NM_003368                                   cysteine-type peptidase
                              Ubiquitin carboxyl-terminal hydrolase 1;USP1;ortholog activity
8.15    USP10     NM_005153                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 10;USP10;ortholog
-2.22   USP18     NM_017414                                   cysteine-type peptidase
                              Ubl carboxyl-terminal hydrolase 18;USP18;ortholog activity
-2.09   USP2      NM_004205                                   cysteine-type peptidase
                              Ubiquitin carboxyl-terminal hydrolase 2;USP2;ortholog activity
4.28    USP20     NM_006676                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 20;USP20;ortholog
-3.02   USP21     NM_012475                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 21;USP21;ortholog
2.24    USP24     XM_165973                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 24;USP24;ortholog
-3.24   USP33     NM_015017                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 33;USP33;ortholog
5.40    USP35     XM_290527                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 35;USP35;ortholog
-2.22   USP44     NM_032147                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 44;USP44;ortholog
7.92    USP46     NM_022832                                   cysteine-type peptidase activity
                              Ubiquitin carboxyl-terminal hydrolase 46;USP46;ortholog
-2.25   USP5      NM_003481                                   cysteine-type peptidase
                              Ubiquitin carboxyl-terminal hydrolase 5;USP5;ortholog activity
-2.19   USP52     NM_014871                                   cysteine-type peptidase activity;exoribonucle
                              PAB-dependent poly(A)-specific ribonuclease subunit 2;PAN2;ortholog
3.72    VCX3      NM_016379   Variable charge X-linked protein 3;VCX3A;ortholog
2.96    VDRIP     NM_014166                                   transcription factor activity;transcription
                              Mediator of RNA polymerase II transcription subunit 4;MED4;ortholog facto
-2.67   VHL       NM_000551                                   ligase activity
                              Von Hippel-Lindau disease tumor suppressor;VHL;ortholog
2.99    VILL      NM_015873                                   structural constituent of cytoskeleton;actin b
                              Villin-like protein;VILL;ortholog
-2.47   VIM       NM_003380   Vimentin;VIM;ortholog           structural constituent of cytoskeleton
3.29    VNN2      NM_004665                                   hydrolase activity
                              Vascular non-inflammatory molecule 2;VNN2;ortholog
3.51    VNN3      NM_018399                                   hydrolase activity
                              Vascular non-inflammatory molecule 3;VNN3;ortholog
-2.68   VPS16     NM_022575   Vacuolar protein sorting-associated protein 16 homolog;VPS16;ortholog
-2.26   VPS29     NM_016226   Vacuolar protein sorting-associated protein 29;VPS29;ortholog
-2.51   VPS35     NM_018206   Vacuolar protein sorting-associated protein 35;VPS35;ortholog
-2.18   VPS52     NM_022553   Vacuolar protein sorting-associated protein 52 homolog;VPS52;ortholog
-2.20   VSTM1     NM_198481                                   receptor activity
                              V-set and transmembrane domain-containing protein 1;VSTM1;ortholog
2.79    VSTM2B    XM_292785                                   receptor activity
                              V-set and transmembrane domain-containing protein 2B;VSTM2B;ortholog
-2.90   VWA1      NM_022834   von Willebrand factor A domain-containing protein 1;VWA1;ortholog
-2.63   VWF       NM_000552   von Willebrand antigen 2;VWF;ortholog
-2.28   WAC       NM_016628   WW domain-containing adapter protein with coiled-coil;WAC;ortholog
-2.62   WDR20     NM_144574   WD repeat-containing protein 20;WDR20;ortholog
-2.54   WDR88     NM_173479   WD repeat-containing protein 88;WDR88;ortholog
-2.44   WNT10B    NM_003394   Protein Wnt-10b;WNT10B;ortholog receptor binding
-2.92   WNT16     NM_016087   Protein Wnt-16;WNT16;ortholog   receptor binding
2.41    WNT4      NM_030761   Protein Wnt-4;WNT4;orthologreceptor binding
-2.54   XK        NM_021083   Membrane transport protein XK;XK;ortholog
2.01    XKRX      NM_212559   XK-related protein 2;XKRX;ortholog
2.34    XPA       NM_000380                                   damaged DNA binding
                              DNA repair protein complementing XP-A cells;XPA;ortholog
-2.35   XPO6      NM_015171   Exportin-6;XPO6;ortholog
3.35    YAF2      NM_005748                                   transcription
                              YY1-associated factor 2;YAF2;ortholog factor activity;transcription facto
-2.62   YARS2     NM_015936                                   aminoacyl-tRNA ligase activity;nucleic acid
                              Tyrosyl-tRNA synthetase, mitochondrial;YARS2;ortholog
4.98    YEATS2    NM_018023                                   transcription factor activity;chromatin binding
                              YEATS domain-containing protein 2;YEATS2;ortholog
-2.23   YIPF6     NM_173834   Protein YIPF6;YIPF6;ortholog
4.04    YRDC      NM_024640   YrdC domain-containing protein, mitochondrial;YRDC;ortholog
-3.49   ZBED5     NM_021211                                   transcription 5;ZBED5;ortholog
                              Zinc finger BED domain-containing protein factor activity;transcription facto
2.27    ZBTB33    NM_006777                                   transcription factor
                              Transcriptional regulator Kaiso;ZBTB33;ortholog activity;transcription facto
2.65    ZC3H12D   XM_291154                                   nucleic acid binding
                              Zinc finger CCCH domain-containing protein 12D;ZC3H12D;ortholog
4.53    ZCCHC8    NM_017612                                   nucleic acid binding
                              Zinc finger CCHC domain-containing protein 8;ZCCHC8;ortholog
-3.15   ZDHHC12   NM_032799   Probable palmitoyltransferase ZDHHC12;ZDHHC12;ortholog
-2.48   ZDHHC6    NM_022494   Probable palmitoyltransferase ZDHHC6;ZDHHC6;ortholog
-2.23   ZFP276    NM_152287                                   transcription
                              Zinc finger protein 276;ZNF276;ortholog factor activity;transcription facto
-1.96   ZFYVE28    XM_035371                                  transcription factor activity;transcription facto
                               Zinc finger FYVE domain-containing protein 28;ZFYVE28;ortholog
4.39    ZMPSTE24   NM_005857                                  metallopeptidase activity
                               CAAX prenyl protease 1 homolog;ZMPSTE24;ortholog
3.94    ZMYND11    NM_006624                                  transcription factor activity;transcription
                               Zinc finger MYND domain-containing protein 11;ZMYND11;ortholog facto
2.45    ZMYND19    NM_138462                                  transcription factor activity;transcription
                               Zinc finger MYND domain-containing protein 19;ZMYND19;ortholog facto
3.86    ZNF124     NM_003431   Zinc finger protein 124;ZNF124;ortholog
-2.38   ZNF161     NM_007146                                  transcription factor activity;transcription facto
                               Vascular endothelial zinc finger 1;VEZF1;ortholog
2.53    ZNF174     NM_003450                                  transcription
                               Zinc finger protein 174;ZNF174;ortholog factor activity;transcription facto
2.70    ZNF248     NM_021045                                  transcription
                               Zinc finger protein 248;ZNF248;ortholog factor activity;transcription facto
-2.34   ZNF281     NM_012482                                  transcription
                               Zinc finger protein 281;ZNF281;ortholog factor activity;transcription facto
-2.42   ZNF288     NM_015642                                  transcription factor activity;transcription
                               Zinc finger and BTB domain-containing protein 20;ZBTB20;ortholog facto
-2.35   ZNF289     NM_032389                                  nucleic acid protein 2;ARFGAP2;ortholog
                               ADP-ribosylation factor GTPase-activating binding;protein binding;small GT
-2.62   ZNF300     NM_052860                                  transcription
                               Zinc finger protein 300;ZNF300;ortholog factor activity;transcription facto
-2.15   ZNF326     NM_182975   Zinc finger protein 326;ZNF326;ortholog
3.08    ZNF341     NM_032819                                  transcription
                               Zinc finger protein 341;ZNF341;ortholog factor activity;transcription facto
2.42    ZNF385D    NM_024697                                  nuclease activity;transcription factor activity;
                               Zinc finger protein 385D;ZNF385D;ortholog
-2.28   ZNF397     NM_032347                                  transcription
                               Zinc finger protein 397;ZNF397;ortholog factor activity;transcription facto
2.97    ZNF406     NM_020863                                  transcription factor activity;transcription facto
                               Zinc finger protein ZFAT;ZFAT;ortholog
-3.94   ZNF42      NM_003422                                  transcription factor activity;transcription facto
                               Myeloid zinc finger 1;MZF1;ortholog
-2.14   ZNF44      NM_016264                                  transcription factor activity;transcription facto
                               Zinc finger protein 44;ZNF44;ortholog
2.99    ZNF446     NM_017908                                  transcription
                               Zinc finger protein 446;ZNF446;ortholog factor activity;transcription facto
-2.35   ZNF454     NM_182594                                  transcription
                               Zinc finger protein 454;ZNF454;ortholog factor activity;transcription facto
-2.18   ZNF493     NM_175910                                  transcription
                               Zinc finger protein 493;ZNF493;ortholog factor activity;transcription facto
-2.58   ZNF501     NM_145044                                  transcription
                               Zinc finger protein 501;ZNF501;ortholog factor activity;transcription facto
-2.47   ZNF529     NM_020951                                  transcription
                               Zinc finger protein 529;ZNF529;ortholog factor activity;transcription facto
2.05    ZNF537     NM_020856                                  transcription factor activity;transcription facto
                               Teashirt homolog 3;TSHZ3;ortholog
3.19    ZNF609     XM_042833   Zinc finger protein 609;ZNF609;ortholog
-2.42   ZNF621     NM_198484                                  transcription
                               Zinc finger protein 621;ZNF621;ortholog factor activity;transcription facto
2.23    ZNF643     NM_023070                                  transcription
                               Zinc finger protein 643;ZNF643;ortholog factor activity;transcription facto
5.53    ZNF654     NM_018293                                  nuclease
                               Zinc finger protein 654;ZNF654;ortholog activity;transcription factor activity;
2.08    ZNF670     NM_033213                                  transcription
                               Zinc finger protein 670;ZNF670;ortholog factor activity;transcription facto
-2.28   ZNF673     NM_017776   Protein ZNF673;ZNF673;ortholog transcription factor activity;transcription facto
2.68    ZNF701     NM_018260                                  transcription
                               Zinc finger protein 701;ZNF701;ortholog factor activity;transcription facto
-2.48   ZNF747     NM_023931                                  transcription factor activity;transcription facto
                               KRAB domain-containing protein ZNF747;ZNF747;ortholog
3.35    ZNF76      NM_003427                                  transcription factor activity;transcription facto
                               Zinc finger protein 76;ZNF76;ortholog
2.44    ZNF765     NM_138372                                  transcription
                               Zinc finger protein 765;ZNF765;ortholog factor activity;transcription facto
2.18    ZNF813     XM_064903                                  transcription
                               Zinc finger protein 813;ZNF813;ortholog factor activity;transcription facto
-2.80   ZNFN1A3    NM_012481                                  transcription
                               Zinc finger protein Aiolos;IKZF3;ortholog factor activity;transcription facto
2.36    ZSCAN18    NM_023926                                  transcription factor activity;transcription facto
                               Zinc finger and SCAN domain-containing protein 18;ZSCAN18;ortholog
2.25    ZSWIM2     NM_182521                                  transcription factor activity;transcription facto
                               Zinc finger SWIM domain-containing protein 2;ZSWIM2;ortholog
2.85    ZYG11B     XM_038291   Protein zyg-11 homolog B;ZYG11B;ortholog
            GO Biological Process           GO Cellular Component Panther Protein Class
                                            microtubule                     non-motor microtubule binding protein
            cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;cellular component morpho
            intracellular protein transport;nuclear transport
            cellular amino acid catabolic process                           dehydrogenase;reductase
            immune system process;extracellular transport                   ATP-binding cassette (ABC) transporter
                                                                              toxin
            immune system process;extracellular transport;response toATP-binding cassette (ABC) transporter
            lipid transport;lipid metabolic process                         transporter
                                                                            hydrolase
            immune system process;proteolysis;response to toxin             serine protease;serine protease
            immune system process;proteolysis;response to toxin             serine protease;serine protease
                                                                            hydrolase
                                            actin cytoskeleton
            cell motion;ectoderm development;nervous system development     structural protein;actin family cytoskeletal protein
            protein metabolic process                                       transferase
                                                                            dehydrogenase
            respiratory electron transport chain;acyl-CoA metabolic process;acyl-CoA metabolic process
            acyl-CoA metabolic process;acyl-CoA metabolic process esterase
                                                                            protein phosphatase;protein phosphatase
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
                                                                            phosphatase;phosphatase
            cation transport;phosphate metabolic process;protein amino acid phosphorylation;proteolysis;mesoderm development;
                                                                            phosphatase;phosphatase
            fatty acid metabolic process                                    ligase
                                            actin cytoskeleton              actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;c
                                            actin cytoskeleton              actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;c
                                            actin cytoskeleton              actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;c
                                            actin cytoskeleton              non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                            actin cytoskeleton              actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;c
                                            actin cytoskeleton              actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;c
                                                                            serine/threonine protein kinase receptor;TGF-beta receptor;
            cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protei
            cellular amino acid biosynthetic process;proteolysis            metalloprotease;metalloprotease
            purine base metabolic process                                   deaminase
                                                                              adhesion;proteolysis;signal transduction;cell-matrix adhes
            fertilization;signal transduction;cell-matrix adhesion;cell-cellmetalloprotease;metalloprotease
                                                                            metalloprotease;metalloprotease
            signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
                                                                            metalloprotease;metalloprotease
            signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
            cellular amino acid biosynthetic process                        decarboxylase
            protein complex assembly actin cytoskeleton                     non-motor actin binding protein
            carbohydrate metabolic process                                  dehydrogenase;reductase
            carbohydrate metabolic process                                  dehydrogenase;reductase
            cellular amino acid metabolic process                           oxidoreductase
                                                                            receptor
            cell surface receptor linked signal transduction;fatty acid metabolic process;cell surface receptor linked signal transduc
rotein;ADNP;ortholog
            proteolysis                                                     serine protease inhibitor

                                                                        transduction;cell-cell adhesion;cell surface protein;immuno
             immune system process;cell surface receptor linked signal transmembrane receptor regulatory/adaptor receptor linked
             glycogen metabolic process                                glycosyltransferase;glycosidase
             phospholipid metabolic process                            acyltransferase
             cellular amino acid metabolic process                     transaminase
             purine base metabolic process                             hydrolase
             visual perception;sensory perception                      chaperone
                                                                       nucleotide kinase;nucleotide kinase
             purine base metabolic process;pyrimidine base metabolic process
             metabolic process                                         reductase
             porphyrin metabolic process                               transferase
             porphyrin metabolic process                               transferase
             metabolic process                                         dehydrogenase
             metabolic process                                         dehydrogenase
            metabolic process                                          dehydrogenase
            glycolysis                                                 aldolase
            DNA repair
            protein targeting;signal transduction;signal transduction  enzyme modulator
                                                                       membrane traffic protein
            intracellular protein transport;ectoderm development;nervous system development
egion candidate gene 8 protein;ALS2CR8;ortholog
                                                                       homeobox development;skeletal system development
            regulation of transcription from RNA polymerase II promoter;mesodermtranscription factor;DNA binding protein
            polysaccharide metabolic process                           deacetylase
            purine base metabolic process                              deaminase
            cellular amino acid catabolic process                      dehydrogenase
            cell cycle;proteolysis;cell cycle                          ligase

NKRD10;ortholog
NKRD31;ortholog
hosphatase inhibitor activity;phosphatase regulator activity              phosphatase inhibitor
            proteolysis                                                   metalloprotease;metalloprotease
            intracellular protein transport;vesicle-mediated transport    membrane traffic protein
                                             microtubule                  non-motor microtubule adhesion;cell cycle;cell surface rece
            apoptosis;cell cycle;cell surface receptor linked signal transduction;apoptosis;cell binding protein
            protein amino acid acetylation;proteolysis                    serine protease;serine protease
            DNA repair                                                    endodeoxyribonuclease;exodeoxyribonuclease;nuclease

             lipid transport;lipid metabolic process                     transporter;apolipoprotein

           lipid transport;cholesterol metabolic process                 transporter;apolipoprotein
           lipid transport;cholesterol metabolic process                 transporter;apolipoprotein
           lipid transport;cholesterol metabolic process                 transporter;apolipoprotein
           transport                                                     transporter
           metabolic process                                             reductase
           intracellular protein transport;vesicle-mediated transport    small GTPase
                                                                         G-protein modulator
           cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                         small GTPase
           G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
           cell motion                                                   G-protein modulator
mall GTPase regulator activity                                           G-protein modulator
                                            cytoskeleton                 cytoskeletal protein
           intracellular signaling cascade;intracellular signaling cascade
                                                                         signaling molecule;G-protein modulator
           intracellular signaling cascade;intracellular signaling cascade
                                                                         signaling molecule;G-protein modulator
           intracellular signaling cascade;intracellular signaling cascade
                                                                         small GTPase
           synaptic vesicle exocytosis;intracellular protein transport;exocytosis
                                            actin cytoskeleton           actin family cytoskeletal protein
           cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                            actin cytoskeleton           actin family cytoskeletal protein
           cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
           cell motion                      actin cytoskeleton           actin family cytoskeletal protein


                                                                       hydrolase
            sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
                                                                       hydrolase
            sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
            cellular amino acid metabolic process                      metalloprotease;deacetylase;metalloprotease
                                                                       hydroxylase
            transmembrane receptor protein tyrosine kinase signaling pathway;protein modification process;transmembrane recept
            protein modification process                               hydroxylase
                                                                       hydrolase
            protein metabolic process;cellular component morphogenesis;cellular component morphogenesis;cellular component m
            protein metabolic process                                  hydrolase
            regulation of transcription from RNA polymerase II promoterCREB transcription factor;nucleic acid binding
ein 2;ATF7IP2;ortholog
                                                                       nucleotide kinase;non-receptor serine/threonine protein kina
            immune system process;induction of apoptosis;cell cycle;DNA repair;protein amino acid phosphorylation;cell cycle;res
            cation transport;lipid transport;lipid metabolic process     transporter;hydrolase
            cation transport;cellular calcium ion homeostasis            cation transporter;ion channel;hydrolase
            cation transport                                             ATP synthase

                                            proton-transporting ATP synthase synthase;ion channel;hydrolase
                                                                           ATP acid metabolic process
            cation transport;nucleobase, nucleoside, nucleotide and nucleic complex
                                            proton-transporting ATP synthase synthase;ion channel;hydrolase
                                                                           ATP acid transport;nucleobase, nucleoside, nucleotide and
            cation transport;nucleobase, nucleoside, nucleotide and nucleic complex
            cation transport;purine base metabolic process                 ATP synthase;hydrolase
            cation transport;cellular calcium ion homeostasis              cation transporter;ion channel;hydrolase
                                                                           transporter;hydrolase
            cation transport;lipid transport;lipid metabolic process;cellular calcium ion homeostasis
            neurological system process                                    RNA binding protein
            mitosis;protein amino acid phosphorylation;cytokinesis;mitosis non-receptor serine/threonine protein kinase;non-receptor se

                                                                       G-protein modulator
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway;dorsal/ventra
            carbohydrate metabolic process                             glycosyltransferase
            regulation of transcription from RNA polymerase II promotertranscription factor;nucleic acid binding

            induction of apoptosis                                      signaling molecule
                                                                        homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;skeletal sy
                                                                        homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;skeletal sy
                                                                        signaling molecule
            gamete generation;induction of apoptosis;cell cycle;cell cycle;mesoderm development;hemopoiesis

                                          extracellular matrix      extracellular matrix glycoprotein
            cell adhesion;cell adhesion;ectoderm development;mesoderm development;nervous system development
                                                                    esterase
            neurological system process;neuromuscular synaptic transmission;neuromuscular synaptic transmission

            protein metabolic process                                    translation initiation factor
                                             SNARE complex
            intracellular protein transport;vesicle-mediated transport   SNARE protein

                                           extracellular matrix           receptor;extracellular matrix protein
            cell surface receptor linked signal transduction;cell-cell adhesion;cell surface receptor linked signal transduction;cell-ce
            proteolysis                                                   ubiquitin-protein ligase


                                                                           membrane trafficking regulatory protein
              neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
                                                                           membrane trafficking regulatory protein
              neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
              negative regulation of apoptosis                             protease inhibitor
              neurological system process;induction of apoptosis
              neurological system process;induction of apoptosis
                                                                           serine/threonine protein kinase receptor;TGF-beta receptor;
              transmembrane receptor protein serine/threonine kinase signaling pathway;cytokine-mediated signaling pathway;protei
              apoptosis
g protein 3-like;BNIP3L;ortholog
              induction of apoptosis                                       signaling molecule

            immune system process;proteolysis;response to toxin         serine protease;serine protease
            proteolysis                                                 ubiquitin-protein ligase
                                                                        zinc finger II promoter;cell cycle
            cell cycle;DNA repair;regulation of transcription from RNA polymerase transcription factor


            mitosis;DNA repair;mitosis;chromosome segregation            DNA helicase;helicase

            neurological system process;synaptic transmission;synaptic transmission
                                            plasma membrane               receptor linked receptor regulatory/adaptor protein
            cell surface receptor linked signal transduction;cell surface transmembranesignal transduction
                                                                          ubiquitin-protein ligase
            synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteol
                                                                          DNA repair;DNA recombination;establishment or maintenan
            regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
                                                                          hydrolase
              signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
                                                                          transcription factor
              transcription initiation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
              mesoderm development;mammary gland development
                                                                          non-receptor serine/threonine protein kinase;non-receptor se
              mitosis;protein amino acid phosphorylation;mitosis;chromosome segregation;embryonic development
              coenzyme metabolic process;fatty acid metabolic process ligase
              translation                                                 translation initiation factor;nuclease
              coenzyme metabolic process;fatty acid metabolic process ligase


n 1;SYCE1;ortholog
 ASSF7;ortholog




ecause currently there is support for the transcript but not for the protein.

ransporter activity                                                             transporter


                                                                            receptor linked signal transduction
              cell surface receptor linked signal transduction;cell surface kinase modulator



            carbohydrate transport;carbohydrate metabolic process               transporter;receptor
MAN;ortholog




                                                                                kinase;kinase
ferase activity;nucleic acid binding                                            RNA methyltransferase;RNA binding protein
              complement activation;proteolysis;blood coagulation               serine protease;serine protease;complement component
              complement activation;proteolysis;response to stimulus            serine protease;serine protease;complement component
              cellular amino acid catabolic process;proteolysis                 protease;protease

                                                                            transcription cofactor
              cell cycle;DNA repair;regulation of transcription from RNA polymerase II promoter;cell cycle
              intracellular signaling cascade;intracellular signaling cascade



              protein modification process                               methyltransferase
              embryonic development
                                                                         G-protein coupled receptor
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
              metabolic process                                          transfer/carrier protein
              ectoderm development;nervous system development          hydrolase
orf26;ortholog



             cell cycle;DNA replication;cell cycle                     replication origin binding protein



                                                                       protein phosphatase;protein phosphatase
             transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane



ty, transferring glycosyl groups                                       glycosyltransferase


DC15;ortholog




homolog;RMND1;ortholog




                                                                       hydrolase




             protein modification process

EM38B;ortholog

                                                                        calmodulin
           cell cycle;calcium-mediated signaling;cell cycle;calcium-mediated signaling
                                                                        voltage-gated calcium channel;voltage-gated ion channel
           muscle contraction;neurotransmitter secretion;neuronal action potential propagation;cation transport;synaptic transmis
                                                                        voltage-gated calcium channel;voltage-gated ion channel
           neuronal action potential propagation;cation transport;cell communication;cell communication
                                                                        voltage-gated calcium channel;voltage-gated ion channel
           muscle contraction;neurotransmitter secretion;neuronal action potential propagation;cation transport;synaptic transmis
                                                                        voltage-gated calcium channel;voltage-gated ion channel
           muscle contraction;neurotransmitter secretion;neuronal action potential propagation;cation transport;synaptic transmis
                                                                        voltage-gated calcium channel;voltage-gated ion channel
           muscle contraction;neurological system process;cation transport;protein targeting;calcium-mediated signaling;calcium-
subunit;CACNG6;ortholog
           cation transport                                             voltage-gated calcium channel;voltage-gated ion channel
                                                                        non-receptor serine/threonine protein kinase;non-receptor se
           muscle contraction;calcium-mediated signaling;protein amino acid phosphorylation;calcium-mediated signaling
           immune system process;defense response to bacterium protease inhibitor;antibacterial response protein
                                         actin cytoskeleton             non-motor actin binding protein
           cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
           induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;I-kappaB kinase/NF-kappaB cascad
             apoptosis;transcription from RNA polymerase II promoter
n;CARKD;ortholog
             neurological system process;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic tra
             apoptosis;proteolysis                                      cysteine protease;cysteine protease
             proteolysis                                                cysteine protease inhibitor
             metabolic process                                          dehydrogenase;reductase
                                                                        chromatin/chromatin-binding protein
             apoptosis;regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin arch
 C114;ortholog
 C121;ortholog
 C128;ortholog
 C132;ortholog
 C151;ortholog


 C74A;ortholog


                                                                       G-protein coupled receptor
             neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein s
                                                                       chemokine
             immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
                                                                       chemokine
             immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
                                                                       chemokine
             macrophage activation;cytokine-mediated signaling pathway;cell-cell signaling;cell motion;cytokine-mediated signaling
             spermatogenesis;mitosis;mitosis                           kinase activator
             mitosis;mitosis                                           kinase activator
             mitosis;mitosis                                           kinase activator
             mitosis;mitosis                                           kinase activator
                                          nucleus                      transcription cofactor;kinase activator
             cell cycle;RNA elongation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promote
                                          MHC protein complex          immunoglobulin receptor superfamily;immunoglobulin recep
             antigen processing and presentation;cellular defense response

                                                                           receptor
             macrophage activation;extracellular transport;negative regulation of apoptosis
                                                                           m
             lysosomal transport;intracellular protein transport;proteolysis embrane trafficking regulatory protein
                                                                           immunoglobulin receptor superfamily;immunoglobulin recep
             immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor p
                                                                           membrane-bound signaling molecule;immunoglobulin recep
             B cell mediated immunity;cell adhesion;cell adhesion;cellular defense response
             mitosis;cytokinesis;mitosis cytoskeleton                      small GTPase;cytoskeletal protein
             mitosis;protein metabolic process;mitosis                     ubiquitin-protein ligase
                                                                           protein phosphatase;protein phosphatase
             cell cycle;phosphate metabolic process;protein modification process;cell cycle
                                                                           protein phosphatase;protein phosphatase
             cell cycle;phosphate metabolic process;protein modification process;cell cycle
             mitosis;mitosis
                                                                           kinase activator;chaperone
             mitosis;signal transduction;protein folding;cytokinesis;mitosis;signal transduction;cellular component morphogenesis;c
                                                                           small GTPase
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
             cell cycle;DNA replication;cell cycle                         replication origin binding protein
             cell cycle;cell cycle                                         transcription factor

                                                                            cadherin
           signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                            cadherin
           signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                            cadherin
           sensory perception of sound;sensory perception;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhe
           mitosis;protein amino acid phosphorylation;mitosis               non-receptor serine/threonine protein kinase;non-receptor se
           mitosis;protein amino acid phosphorylation;mitosis               non-receptor serine/threonine protein kinase;non-receptor se
4;CDKN2A;ortholog
                                                                            transcription factor;nucleic acid binding
           natural killer cell activation;apoptosis;regulation of transcription from RNA polymerase II promoter;mesoderm developm
ein 1;CEND1;ortholog
                                                                            nucleic acid binding;G-protein modulator
           G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa
           immune system process;response to toxin                          esterase
             immune system process;response to toxin                     esterase
             complement activation;proteolysis;response to stimulus      serine protease;serine protease;complement component
                                             actin cytoskeleton          non-motor component morphogenesis;cellular component m
             protein complex assembly;cellular component morphogenesis;cellular actin binding protein
             spermatogenesis;female gamete generation                    peptide hormone
ning protein 3, mitochondrial;CHCHD3;ortholog
                                                                         non-receptor serine/threonine protein kinase;non-receptor se
             immune system process;meiosis;calcium-mediated signaling;protein amino acid phosphorylation;meiosis;calcium-med
             phospholipid metabolic process                              kinase;kinase
                                             nucleus                     transcription factor;DNA-directed DNA polymerase;chromat
             regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcription from RNA polymerase
             dorsal/ventral axis specification                           signaling molecule
             sulfur metabolic process                                    transferase
             regulation of transcription from RNA polymerase II promoter

                                                                         kinase;protein signaling
              calcium-mediated signaling;protein modification process;calcium-mediatedphosphatase;kinase;protein phosphatase;ca
              induction of apoptosis
ning protein 2;RSAD2;ortholog
                                                                         interleukin superfamily
              immune system process;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;
              anion transport                                            anion channel
                                           tight junction                tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                           tight junction                tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis

                                           tight junction                 tight junction
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                          membrane-bound
             B cell mediated immunity;natural killer cell activation;response to stimulus signaling molecule;receptor;defense/imm
                                                                          membrane trafficking
             neurological system process;lysosomal transport;intracellular protein transport regulatory protein
             proteolysis                                                  serine protease;serine protease
                                                                          nucleotide kinase;nucleotide kinase
             purine base metabolic process;pyrimidine base metabolic process
             cation transport;signal transduction;signal transduction     cyclic nucleotide-gated ion channel;voltage-gated potassium

                                                                          immunoglobulin receptor superfamily;protein phosphatase;p
             immune system process;muscle contraction;induction of apoptosis;cell cycle;cell surface receptor linked signal transd
                                            extracellular matrix          extracellular matrix structural protein
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development
                                            extracellular matrix          extracellular matrix structural protein
             cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component

                                           extracellular matrix      extracellular matrix structural protein
             cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component


                                             extracellular component morphogenesis;cellular component morphogenesis
             cellular component morphogenesis;cellularmatrix                extracellular matrix structural protein
                                             extracellular matrix           extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component morphogenesis;cellular compon
                                             extracellular matrix           extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component morphogenesis;cellular compon
                                             extracellular matrix           extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;mesoderm development;skeletal system developme
             asymmetric protein localization extracellular matrix           extracellular matrix structural protein
             neurological system process;metabolic process                  methyltransferase
             proteolysis
             coenzyme metabolic process
                                             actin cytoskeleton             non-motor actin binding protein
             intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular c
                                             actin cytoskeleton             non-motor actin binding protein
             intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular c
             proteolysis                                                    metalloprotease;metalloprotease
             proteolysis                                                    metalloprotease;metalloprotease
             proteolysis                                                    metalloprotease;metalloprotease
                                             surface receptor linked signal receptor;extracellular matrix protein
             immune system process;cell extracellular matrix                transduction;cell surface receptor linked signal transduction
             mRNA polyadenylation                                           endoribonuclease;mRNA polyadenylation factor;nuclease
                                                                            acetyltransferase;acyltransferase
             cellular amino acid metabolic process;fatty acid metabolic process
                                                                            acetyltransferase;acyltransferase
             cellular amino acid metabolic process;fatty acid metabolic process
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

                                             actin cytoskeleton
             mesoderm development;muscle organ development                 actin family cytoskeletal protein
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
 ng;calmodulin binding;calcium-dependent phospholipid binding              annexin;calmodulin
                                                                           structural protein;chaperone
             immune system process;muscle contraction;visual perception;sensory perception;protein folding;response to stress
             visual perception;sensory perception                          structural protein
             visual perception;sensory perception                          structural protein
             carbohydrate metabolic process                                dehydrogenase;reductase
             calcium-mediated signaling;calcium-mediated signaling         calcium-binding protein
             protein amino acid glycosylation                              glycosyltransferase
SMD2;ortholog
                                             actin cytoskeleton            actin family cytoskeletal protein
             immune system process;mesoderm development;muscle organ development
             immune system process;proteolysis                             cysteine protease inhibitor
 P1;CSTP1;ortholog
             regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
                                             actin cytoskeleton            non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                             intermediate filament cytoskeleton;cell
                                                                           intermediate filament binding protein;cell junction protein;ce
             signal transduction;cell adhesion;signal transduction;cell adhesion junction
             pyrimidine base metabolic process                             ligase
             pyrimidine base metabolic process                             ligase
             proteolysis                                                   cysteine protease;cysteine protease
                                             actin cytoskeleton            non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
 ;PARC;ortholog
                                             extracellular matrix          transporter;apolipoprotein;membrane-bound signaling molec
             immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp


              signal transduction;signal transduction                      G-protein modulator
              translation                                                  ribosomal protein
                                                                           oxygenase
              respiratory electron transport chain;steroid metabolic process
                                                                           hydroxylase;oxygenase
              respiratory electron transport chain;fatty acid metabolic process
                                                                           oxygenase
              respiratory electron transport chain;cholesterol metabolic process
                                                                           oxygenase
              respiratory electron transport chain;cholesterol metabolic process
                                                                           oxygenase
              respiratory electron transport chain;fatty acid metabolic process;steroid metabolic process
              metabolic process                                            methyltransferase
                                                                           chemokine
              immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
              MAPKKK cascade;MAPKKK cascade                                signaling molecule
              complement activation;response to stimulus                   complement component
              tRNA aminoacylation for protein translation                  aminoacyl-tRNA synthetase
                                                                           o
              oxidative phosphorylation;respiratory electron transport chainxidoreductase
              gamete generation                                            RNA binding protein
                                              system process;nuclear mRNA splicing, via spliceosome;protein metabolic process;ecto
              spermatogenesis;neurologicalribonucleoprotein complex ribonucleoprotein

                                                                             homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                                                             cadherin
              signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                               microtubule                   non-receptor component morphogenesis;cellular componen
              neurological system process;protein amino acid phosphorylation;cellular serine/threonine protein kinase;non-receptor se
              DNA repair
              RNA catabolic process                                          hydrolase
                                               microtubule                   microtubule binding motor protein
              intracellular protein transport;vesicle-mediated transport;cellular component morphogenesis;cellular component morpho
              immune system process;cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;c
              cellular amino acid metabolic process                          decarboxylase
                                                                             nucleic acid binding;G-protein modulator
              G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa
                                                                             RNA helicase;translation
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;translation initiation factor;helicase
                                                                         RNA helicase;helicase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
tivity;nucleic acid binding                                              RNA helicase;helicase
                                                                         RNA helicase;helicase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                         RNA helicase;helicase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                         RNA helicase;helicase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                         DNA helicase;helicase;hydrolase
               meiosis;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;meiosis
               fatty acid beta-oxidation                                 dehydrogenase;reductase

                                                                            nucleic acid binding
              intracellular signaling cascade;intracellular signaling cascade
                                                                            receptor;guanyl-nucleotide exchange factor
protein binding;small GTPase regulator activity;guanyl-nucleotide exchange factor activity
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                            aldolase
                                             intermediate component morphogenesis;ectoderm development;cellular component morp
              cellular component morphogenesis;cellularfilament cytoskeletonstructural protein;intermediate filament
                                                                            kinase;kinase
              intracellular signaling cascade;lipid metabolic process;intracellular signaling cascade
                                                                            receptor;reductase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;lipid metabolic process
              DNA metabolic process;pyrimidine base metabolic processreductase
                                                                            signaling signaling cascade;cell-cell
              cell cycle;cell surface receptor linked signal transduction;intracellularmolecule;protease;proteasesignaling;proteolysis;c
              metabolic process                                             dehydrogenase;reductase
ransporter activity                                                         transporter


d genome annotation processing.
                                                                        transmembrane receptor regulatory/adaptor protein
           neurological system process;cell surface receptor linked signal transduction;nerve-nerve synaptic transmission;cell sur
                                                                        acyltransferase
                                                                        homeobox transcription factor;DNA binding protein
           regulation of transcription from RNA polymerase II promoter;segment specification;mesoderm development;skeletal sys
                                                                        DNA strand-pairing protein;hydrolase
           immune system process;meiosis;DNA repair;DNA recombination;meiosis;response to stress
                                                                        dehydrogenase
           respiratory electron transport chain;cellular amino acid catabolic process;protein metabolic process

             regulation of transcription from RNA polymerase II promoternucleic acid binding
             regulation of transcription from RNA polymerase II promoternucleic acid binding
                                                                            transcription RNA polymerase binding
             negative regulation of apoptosis;cell cycle;regulation of transcription fromfactor;nucleic acid II promoter;termination of RN
                                             microtubule                    hydrolase;microtubule binding motor protein
             spermatogenesis;fertilization;intracellular protein transport;vesicle-mediated transport;mitosis;cell motion;mitosis;chrom
                                             microtubule                    hydrolase;microtubule binding motor protein
             spermatogenesis;fertilization;intracellular protein transport;vesicle-mediated transport;mitosis;cell motion;mitosis;chrom
                                                                            chaperone
             nuclear mRNA splicing, via spliceosome                         RNA binding protein
                                             microtubule                    hydrolase;small GTPase;microtubule morphogenesis;cellul
             intracellular protein transport;endocytosis;cellular component morphogenesis;cellular component family cytoskeletal pr
                                                                            DNA methyltransferase;DNA binding protein
             DNA metabolic process;establishment or maintenance of chromatin architecture;establishment or maintenance of chro
             DNA metabolic process                                          DNA methyltransferase;DNA binding protein
                                                                            DNA-directed
             B cell mediated immunity;DNA recombination;cellular defense response DNA polymerase
                                                                            guanyl-nucleotide motion;intracellular signaling cascade
             intracellular protein transport;phagocytosis;intracellular signaling cascade;cellexchange factor
                                                                            guanyl-nucleotide motion;intracellular signaling cascade
             intracellular protein transport;phagocytosis;intracellular signaling cascade;cellexchange factor
             protein amino acid glycosylation                               phosphatase;phosphatase
             proteolysis                                                    metalloprotease;metalloprotease
                                                                            hydrolase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                            o
             immune system process;respiratory electron transport chain xidase
                                                                            protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                            protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                            protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                            protein phosphatase;protein phosphatase;kinase
             JNK cascade;glycolysis;phospholipid metabolic process;protein amino acid phosphorylation;JNK cascade inhibitor
                                                                                      cascade;cell surface receptor
             cell surface receptor linked signal transduction;intracellular signaling molecule;enzyme modulator linked signal transd
                                                                                      cascade;cell surface receptor
             cell surface receptor linked signal transduction;intracellular signaling molecule;enzyme modulator linked signal transd

             protein amino acid phosphorylation                           non-receptor tyrosine protein kinase;non-receptor serine/thr
                                                                            transcription factor;nucleic acid binding
             cell cycle;signal transduction;regulation of transcription from RNA polymerase II promoter;cell cycle;signal transduction

                                                                              hydrolase;chaperone
               polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
               polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
                                                                              hydrolase;chaperone
                                                                              peptide hormone
               blood circulation;G-protein coupled receptor protein signaling pathway;cell-cell signaling;G-protein coupled receptor pro
                                                                               transcription from
               cell surface receptor linked signal transduction;regulation oftranscription factor RNA polymerase II promoter;cell surface
                                                                              membrane-bound signaling molecule
               transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein t
               cell motion                                                    calcium-binding protein
                                                                              KRAB box transcription factor;nucleic acid binding
               cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;ectoderm development;mesoderm dev
                                                                              membrane traffic protein;G-protein modulator;calcium-bindin
               neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
9 specific 3;EHMT2;ortholog
               translation                                                    translation initiation factor
               translation                                                    translation initiation factor
               phospholipid metabolic process                                 kinase;kinase
                                                                              hydrolase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                               ribonucleoprotein complex ribonucleoprotein
               mRNA 3'-end processing;ectoderm development;nervous system development
                                               ribonucleoprotein complex ribonucleoprotein
               mRNA 3'-end processing;ectoderm development;nervous system development
                                                                              transcription factor;signaling molecule
               immune system process;intracellular signaling cascade;transcription from RNA polymerase II promoter;intracellular sig
               cell motion                                                    signaling molecule
               cell motion                                                    signaling molecule
               fatty acid metabolic process                                   acyltransferase
or activity;transcription factor activity                                     transcription factor
e 3;EML3;ortholog
               carbohydrate metabolic process                                 deaminase
               metabolic process                                              epimerase/racemase
                                                                              nucleotide phosphatase;nucleotide phosphatase;pyrophosp
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                              nucleotide phosphatase;nucleotide phosphatase;pyrophosp
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
               regulation of transcription from RNA polymerase II promoterchromatin/chromatin-binding protein
                                                                              membrane traffic protein;G-protein modulator;calcium-bindin
               neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
               DNA repair                                                     endodeoxyribonuclease;nuclease
               DNA repair                                                     endodeoxyribonuclease;nuclease
               cell cycle;DNA repair;DNA replication;cell cycle               damaged DNA-binding protein;endodeoxyribonuclease;exod
                                                                              oxidoreductase
               respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
                                                                              oxidoreductase
               respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
               protein modification process                                   isomerase
                                                                              nuclear hormone receptor;receptor;nucleic acid binding
               female gamete generation;neurological system process;mitosis;signal transduction;regulation of transcription from RNA

             respiratory electron transport chain                           oxidoreductase
                                                                            exoribonuclease;nuclease;esterase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
             rRNA metabolic process                                         exoribonuclease;nuclease;hydrolase
                                                                            glycosyltransferase
             polysaccharide metabolic process;protein amino acid glycosylation
                                                                            glycosyltransferase
             polysaccharide metabolic process;protein amino acid glycosylation
             visual perception;sensory perception                           protein phosphatase;protein phosphatase
             visual perception;sensory perception                           protein phosphatase;protein phosphatase
             visual perception;sensory perception                           protein phosphatase;protein phosphatase
                                                                            transferase;ligase;hydrolase
             fatty acid metabolic process;tRNA aminoacylation for protein translation
                                                                            transfer/carrier protein
             lipid transport;vitamin transport;signal transduction;lipid metabolic process;signal transduction;ectoderm development
             cellular amino acid catabolic process                          hydrolase
                                                                            acetyltransferase;chromatin/chromatin-binding protein
             transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture;establishment o
ause it is now thought that this pseudogene is not transcribed.
              transcription from RNA polymerase II promoter                     zinc finger transcription factor


ause it is now thought that this gene is a pseudogene.




igase activity                                                            ubiquitin-protein ligase
              tRNA aminoacylation for protein translation                 aminoacyl-tRNA synthetase
                                                                          acyltransferase;methyltransferase;dehydrogenase;esterase
              cellular amino acid metabolic process;fatty acid biosynthetic process
                                            extracellular matrix          signaling molecule;extracellular matrix glycoprotein;extrace
              visual perception;sensory perception;signal transduction;signal transduction;mesoderm development;skeletal system d
                                            extracellular matrix          signaling molecule;extracellular matrix glycoprotein;extrace
              visual perception;sensory perception;signal transduction;signal transduction;mesoderm development;skeletal system d
              gluconeogenesis                                             carbohydrate phosphatase;carbohydrate phosphatase

              proteolysis
              proteolysis
              proteolysis
              protein metabolic process                                         ubiquitin-protein ligase

                                                                           membrane-bound
              signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion signaling molecule;cell adhesion molecul
              proteolysis                                                  ligase


              metabolic process
                                                                           immunoglobulin receptor superfamily;immunoglobulin recep
              B cell mediated immunity;natural killer cell activation;macrophage activation;signal transduction;signal transduction;res
              cellular glucose homeostasis
              transcription from RNA polymerase II promoter                zinc finger transcription factor
              mesoderm development;skeletal system development             guanyl-nucleotide exchange factor
                                                                           tyrosine protein kinase receptor;tyrosine protein kinase rece
              transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane

                                                                          signal transduction;MAPKKK cascade;JAK-STAT cascade
           negative regulation of apoptosis;cell surface receptor linked tyrosine protein kinase receptor;tyrosine protein kinase rece
NKRD49;ortholog
           sensory perception                                            hydrolase

                                                                isomerase;chaperone;calcium-binding protein
          immune system process;neurological system process;negative regulation of apoptosis;cell cycle;negative regulation of
G43;FKS43_HUMAN;ortholog

ecause it appears to represent expression of a repetitive element.
 d genome annotation processing.

ecause currently there is support for the transcript but not for the protein, and the transcript is a nonsense-mediated mRNA decay ca

ecause currently there is insufficient support for the transcript and the protein is not supported by current protein homology data.

ecause currently there is support for the transcript but not for the protein.
uppressed because currently there is support for the transcript but not for the protein.
FLYWCH1;ortholog
           respiratory electron transport chain;metabolic process        oxygenase
           respiratory electron transport chain;metabolic process        oxygenase
                                                                         RNA binding protein
           nucleobase, nucleoside, nucleotide and nucleic acid transport;induction of apoptosis;nucleobase, nucleoside, nucleotid
           protein amino acid lipidation                                 acyltransferase
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                          receptor linked signal transduction;carbohydrate metabolic
           visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
           metabolic process                                             dehydrogenase



                                                                         glycosidase
              monosaccharide metabolic process;protein amino acid glycosylation
                                                                         serine pathway;cell-matrix adhesion;proteolysis;transmemb
              transmembrane receptor protein serine/threonine kinase signaling protease;serine protease
              metabolic process                                          dehydrogenase;reductase
              cation transport                                           cation transporter
              transport                                                  signaling molecule;RNA binding protein
                                                                         transmembrane receptor regulatory/adaptor protein
              B cell mediated immunity;macrophage activation;transmembrane receptor protein tyrosine kinase signaling pathway;M
uent of cytoskeleton;microtubule binding microtubule                     non-motor microtubule binding protein
                                                                         GABA receptor;GABA receptor
              neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;
                                                                         GABA receptor;GABA receptor
              neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;
              immune system process;apoptosis;cell cycle;apoptosis;MAPKKK cascade;cell cycle;MAPKKK cascade;apoptosis;re
eins-interacting protein 1;GADD45GIP1;ortholog
              carbohydrate metabolic process                             dehydratase;epimerase/racemase
B4GALNT1;ortholog
              protein amino acid glycosylation                           glycosyltransferase
                                                                         glycosyltransferase
              polysaccharide metabolic process;protein amino acid glycosylation
                                                                         G-protein coupled receptor
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway



            immune system process;proteolysis;blood coagulation           serine protease inhibitor
                                                                          zinc finger development;mesoderm development;heart deve
            regulation of transcription from RNA polymerase II promoter;endoderm transcription factor;nuclease
                                            heterotrimeric G-protein complex
                                                                          heterotrimeric G-protein
            response to interferon-gamma;macrophage activation;response to stimulus
                                            heterotrimeric G-protein complex
                                                                          heterotrimeric G-protein
            response to interferon-gamma;macrophage activation;response to stimulus
protein 2;GDAP2;ortholog
                                                                          system development
            female gamete generation;mesoderm development;skeletal growth factor
                                                                          acyltransferase;G-protein modulator
            neurotransmitter secretion;intracellular protein transport;vesicle-mediated transport;intracellular signaling cascade;syna
            lipid metabolic process                                       ligase;esterase;phosphodiesterase
            transcription from RNA polymerase II promoter                 zinc finger transcription factor
                                                                          receptor linked signal transduction
            cell surface receptor linked signal transduction;cell surface peptide hormone
                                            gap junction
            signal transduction;signal transduction                       gap junction
                                            gap junction
            signal transduction;signal transduction                       gap junction

                                                                    ligand-gated ion synaptic transmission;signal transduction;
          neurological system process;anion transport;signal transduction;nerve-nervechannel;ligand-gated ion channel
n 1;GLT8D1;ortholog
n 2;GLT8D2;ortholog
tein 1;GMEB1;ortholog
                                        extracellular matrix           extracellular matrix glycoprotein
            phospholipid metabolic process                             dehydrogenase
                                                                       nucleic acid binding
                                                                       G-protein coupled receptor
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway

                                                                        ionotropic glutamate receptor;ionotropic glutamate receptor
            neurological system process;cation transport;nerve-nerve synaptic transmission;nerve-nerve synaptic transmission
                                                                        ionotropic glutamate receptor;ionotropic glutamate receptor
            neurological system process;cation transport;signal transduction;nerve-nerve synaptic transmission;signal transduction
                                                                        ionotropic glutamate receptor;ionotropic glutamate receptor
            neurological system process;cation transport;cell surface receptor linked signal transduction;nerve-nerve synaptic trans


            translation                                                translation elongation factor;translation release factor
            transcription initiation from RNA polymerase II promoter   transcription factor
                                                                       transcription from RNA polymerase II promoter
            transcription initiation from RNA polymerase II promoter;RNA elongation factor;nucleic acid binding
                                                                       G-protein modulator;calmodulin
            visual perception;sensory perception;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor p

                                                                        basic helix-loop-helix transcription factor;nucleic acid bindin
          regulation of transcription from RNA polymerase II promoter;mesoderm development;angiogenesis;heart development
                                          extracellular matrix
          cell adhesion;cell adhesion;mesoderm development              extracellular matrix glycoprotein
          blood circulation;transport                                   transfer/carrier protein
          blood circulation;transport                                   transfer/carrier protein
27;HCA127;ortholog
                                                                        nucleic from RNA polymerase II
          negative regulation of apoptosis;cell cycle;regulation of transcriptionacid binding;deacetylase promoter;cell cycle;establ
                                                                        nucleic from RNA polymerase II
          negative regulation of apoptosis;cell cycle;regulation of transcriptionacid binding;deacetylase promoter;cell cycle;establ
          translation

            protein amino acid methylation                             methyltransferase
            proteolysis                                                ubiquitin-protein ligase
m-resident ubiquitin-like domain member 2 protein;HERPUD2;ortholog
                                                                       basic helix-loop-helix transcription factor;nucleic acid bindin
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                       basic helix-loop-helix transcription factor;nucleic acid bindin
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste

hatase activity;nucleotide phosphatase activity                       nucleotide phosphatase;nucleotide phosphatase
                                                                      histone
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin arc

            regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
                                            MHC protein complex        major
            antigen processing and presentation;cellular defense response histocompatibility complex antigen
                                            MHC protein complex        major antigen via MHC complex antigen
            antigen processing and presentation of peptide or polysaccharide histocompatibilityclass II;cellular defense response
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;ectoderm development;gut mesoderm development;nervous
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development


otein;HN1;ortholog
            regulation of transcription from RNA polymerase II promotertranscription factor;nucleic acid binding
            nuclear mRNA splicing, via spliceosome                     ribosomal protein
                                                                       signaling molecule
            neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein s
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
1BP3;ortholog
            visual perception;sensory perception                       calmodulin
           protein metabolic process
                                                                   Hsp70 family chaperone
           immune system process;protein folding;protein complex assembly;response to stress
sequence does not appear to represent a valid product.

            nuclear mRNA splicing, via spliceosome                         mRNA splicing factor

                                                                         peptide hormone
            apoptosis;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;mesoderm de
                                            extracellular matrix         structural protein;extracellular matrix structural protein;cell
            signal transduction;cell adhesion;signal transduction;cell adhesion;mesoderm development;skeletal system developme
            regulation of transcription from RNA polymerase II promotertranscription factor
                                                                         chromatin/chromatin-binding protein
            DNA repair;establishment or maintenance of chromatin architecture;establishment or maintenance of chromatin archite


                                                                          interferon superfamily
            response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-m
                                                                          interferon superfamily
            response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-m
                                                                          type II cytokine receptor
            natural killer cell activation;response to interferon-gamma;induction of apoptosis;negative regulation of apoptosis;cytokin
                                                                          interferon superfamily
            response to interferon-gamma;induction of apoptosis;negative regulation of apoptosis;cytokine-mediated signaling pathw
                                                                          interferon superfamily
            natural killer cell activation;response to interferon-gamma;macrophage activation;induction of apoptosis;negative regula

                                                                    defense/immunity protein
            immune system process;signal transduction;signal transduction

                                              immunoglobulin complex
            B cell mediated immunity;response to stimulus                    immunoglobulin
                                                                             type I cytokine cascade;cell-cell signaling;JAK-STAT casca
            B cell mediated immunity;cytokine-mediated signaling pathway;JAK-STAT receptor
                                                                             interleukin superfamily
            B cell mediated immunity;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;m
                                                                             interleukin superfamily
            immune system process;negative regulation of apoptosis;cytokine-mediated signaling pathway;JAK-STAT cascade;neg
                                                                             type I cytokine receptor
            immune system process;cytokine-mediated signaling pathway;MAPKKK cascade;JAK-STAT cascade;cell-cell signalin
                                                                             type I cytokine receptor
            natural killer cell activation;negative regulation of apoptosis;cytokine-mediated signaling pathway;negative regulation of
                                                                             immunoglobulin receptor superfamily;immunoglobulin recep
            natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stim
            cell motion                       actin cytoskeleton             non-motor actin binding protein
                                                                             receptor linked
            cell surface receptor linked signal transduction;cell surface growth factor signal transduction
                                                                             phosphatase;phosphatase
            intracellular protein transport;transmembrane receptor protein tyrosine kinase signaling pathway;cytokine-mediated sig
            regulation of transcription from RNA polymerase II promoter


            immune system process                                       immunoglobulin receptor superfamily;immunoglobulin recep
                                                                        transcription factor;nucleic acid binding
            response to interferon-gamma;regulation of transcription from RNA polymerase II promoter;response to stimulus
                                                                        transcription factor;nucleic acid binding
            response to interferon-gamma;regulation of transcription from RNA polymerase II promoter;response to stimulus
                                                                        homeobox transcription factor;nucleic acid binding
            regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
            proteolysis                                                 ubiquitin-protein ligase
            cell adhesion;cell adhesion                                 cell adhesion molecule
            cell adhesion;cell adhesion                                 cell adhesion molecule
                                                                        chaperone

                                                                      receptor
                                                                      receptor
                                        intermediate component morphogenesis;cellular componentfilament
                                                                      structural protein;intermediate morphogenesis
            cellular component morphogenesis;cellularfilament cytoskeleton
                                        actin cytoskeleton            non-motor actin binding protein
            neurological system process;cellular component morphogenesis;cellular component morphogenesis;cellular componen
                                        actin cytoskeleton            non-motor actin binding protein
            neurological system process;cellular component morphogenesis;cellular component morphogenesis;cellular componen

                                                                      voltage-gated potassium channel;voltage-gated ion channel
            muscle contraction;neurological system process;cation transport;signal transduction;synaptic transmission;signal tran
            muscle contraction;blood circulation;cation transport     voltage-gated potassium channel;voltage-gated ion channel
            cation transport                                          voltage-gated potassium channel;voltage-gated ion channel
            muscle contraction;cation transport                       voltage-gated potassium channel;voltage-gated ion channel
             cation transport;signal transduction;signal transduction   cyclic nucleotide-gated ion channel;voltage-gated potassium
                                                                        G-protein modulator;calcium-binding protein
             G-protein coupled receptor protein signaling pathway;calcium-mediated signaling;calcium-mediated signaling;G-protein
                                                                        voltage-gated
             muscle contraction;neuronal action potential propagation;cation transport potassium channel;voltage-gated ion channel
             cation transport                                           voltage-gated potassium channel;voltage-gated ion channel
             neurological system process;cation transport               voltage-gated potassium channel;voltage-gated ion channel
                                                                        voltage-gated potassium channel;voltage-gated ion
             muscle contraction;neurological system process;cation transport;synaptic transmission;synaptic transmissionchannel
                                                                        voltage-gated potassium channel;voltage-gated ion channel
             muscle contraction;sensory perception of sound;sensory perception;cation transport;synaptic transmission;synaptic tra
             muscle contraction;cation transport                        voltage-gated potassium channel;voltage-gated ion channel
             cation transport                                           enzyme modulator

          intracellular protein transport;exocytosis                        receptor;membrane trafficking regulatory protein
B;RRP1B;ortholog

mall GTPase regulator activity                                              G-protein modulator

           carbohydrate transport;carbohydrate metabolic process      carbohydrate transporter
mall GTPase regulator activity                                        G-protein modulator
           regulation of transcription from RNA polymerase II promoterexoribonuclease;nuclease

             cation transport                                               ligand-gated ion channel;ligand-gated ion channel



                                                                            nucleic acid binding
             general transcription from RNA polymerase II promoter          DNA binding protein

                                                                            methyltransferase



ein KIAA1468;KIAA1468;ortholog
            nuclear mRNA splicing, via spliceosome                          mRNA splicing factor



             transcription from RNA polymerase II promoter

             DNA metabolic process                                       DNA methyltransferase;DNA binding protein
                                                                         nucleic acid binding;G-protein modulator
             G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa


             intracellular protein transport microtubule                     microtubule binding motor protein
                                              microtubule                    microtubule binding motor protein
             intracellular protein transport;mitosis;mitosis;cellular component morphogenesis;cellular component morphogenesis;ce
                                              microtubule                    microtubule binding motor protein
             intracellular protein transport;mitosis;meiosis;mitosis;meiosis;cellular component morphogenesis;cellular component m
             intracellular protein transport microtubule                     microtubule binding motor protein
             intracellular protein transport microtubule                     microtubule binding motor protein
                                              microtubule                    microtubule component morphogenesis;cellular componen
             intracellular protein transport;cellular component morphogenesis;cellularbinding motor protein
                                                                             immunoglobulin receptor superfamily;immunoglobulin linked
             natural killer cell activation;cell surface receptor linked signal transduction;cell-cell signaling;cell surface receptor recep

                                                                        glucosidase;glycosidase
             carbohydrate metabolic process;translation;protein modification process
                                              microtubule
             intracellular protein transport;vesicle-mediated transport microtubule family cytoskeletal protein
             regulation of transcription from RNA polymerase II promoterzinc finger transcription factor
                                               actin cytoskeleton            non-motor actin binding protein
             neurological system process;cellular component morphogenesis;cellular component morphogenesis;cellular componen
                                                                             receptor;defense/immunity protein
             natural killer cell activation;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;response to stim
                                                                             guanyl-nucleotide exchange signaling pathway
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein factor

                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton
                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton
                                        intermediate component morphogenesis;ectoderm development;cellular component morp
                                                                       structural protein;intermediate filament
             cellular component morphogenesis;cellularfilament cytoskeleton
                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton
                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton
                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton

                                        intermediate component morphogenesis;cellular componentfilament
                                                                       structural protein;intermediate morphogenesis
             cellular component morphogenesis;cellularfilament cytoskeleton

                                                                          transcription factor;chromatin/chromatin-binding protein
             regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture;es
                                                                          non-receptor serine/threonine protein
             intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling cascadekinase;non-receptor se
                                              adhesion;cell-cell          extracellular matrix linker protein
             signal transduction;cell-matrixextracellular matrixadhesion;signal transduction;cell-matrix adhesion;cell-cell adhesion;ec
ransporter activity                                                       transporter


                                                                           phosphorylation;cell cycle;intracellular signaling cascade
             cell cycle;intracellular signaling cascade;protein amino acidnon-receptor serine/threonine protein kinase;non-receptor se
                                                                          structural protein
                                                                          non-receptor tyrosine protein kinase;non-receptor tyrosine p
             female gamete generation;immune system process;carbohydrate transport;cell cycle;intracellular signaling cascade;ca
             glycolysis                                                   dehydrogenase
             regulation of transcription from RNA polymerase II promoternucleic acid binding


                                            actin cytoskeleton             actin family cytoskeletal protein
              cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                            intermediate component morphogenesis;cellular componentfilament
                                                                           structural protein;intermediate morphogenesis
              cellular component morphogenesis;cellularfilament cytoskeleton
                                                                           transcription factor
              immune system process;transcription from RNA polymerase II promoter;cellular defense response
                                                                           transcription cofactor
              transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                            cytoskeleton;cell junction
              asymmetric protein localization                              cytoskeletal protein;cell junction protein
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
ecause it is a nonsense-mediated mRNA decay (NMD) candidate.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 tly suppressed because currently there is support for the transcript but not for the protein.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.

d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
y suppressed because the CDS was partial.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.

d genome annotation processing.
d genome annotation processing.
d because currently there is insufficient support for the protein and the transcript and the locus is entirely composed of repetitive seq
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
d genome annotation processing.
tly suppressed because currently support for the transcript exists but not for the protein.
d genome annotation processing.
tly suppressed because it is now thought that this gene is a pseudogene.
tly suppressed because the CDS was partial.
d genome annotation processing.
                                                                            peptide hormone;serine protease;serine protease;protease
             immune system process;blood circulation;lipid transport;apoptosis;lipid metabolic process;proteolysis;mesoderm deve
                                            actin cytoskeleton              actin family cytoskeletal protein
             cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             immune system process
                                            extracellular matrix            receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
                                             adhesion;cell adhesion
             female gamete generation;cellextracellular matrix              receptor;extracellular matrix glycoprotein
                                            extracellular matrix            receptor;extracellular matrix signaling
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein protein pathway

nzyme regulator activity                                                   enzyme modulator
                                          adhesion;cell adhesion
            female gamete generation;cellextracellular matrix              receptor;extracellular matrix glycoprotein
            transport;protein folding                                      apolipoprotein
            immune system process
RC16A;ortholog

             signal transduction;signal transduction
                                            extracellular matrix           receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
                                            extracellular matrix           receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
                                            extracellular matrix           receptor;extracellular matrix signaling
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein protein pathway
             nuclear mRNA splicing, via spliceosome                        mRNA splicing factor
             immune system process                                         transmembrane receptor regulatory/adaptor protein
                                                                           hydrolase;defense/immunity protein
             immune system process;carbohydrate metabolic process;response to stress
1;LZTFL1;ortholog

                                                                      guanyl-nucleotide apoptosis;synaptic transmission;JNK ca
             neurological system process;induction of apoptosis;JNK cascade;induction ofexchange factor
             gamete generation;apoptosis
                                          actin cytoskeleton          actin binding motor protein
             muscle contraction;cell motion;cellular component morphogenesis;cellular component morphogenesis;mesoderm deve

y, hydrolyzing N-glycosyl compounds                                       glycosidase

                                             morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             apoptosis;cellular component microtubule                   non-motor microtubule binding protein
                                                                        non-receptor serine/threonine protein kinase;non-receptor se
             MAPKKK cascade;protein amino acid phosphorylation;MAPKKK cascade
                                                                        non-receptor serine/threonine protein kinase;non-receptor se
             MAPKKK cascade;protein amino acid phosphorylation;MAPKKK cascade
                                                                        non-receptor serine/threonine protein kinase;non-receptor se
             immune system process;muscle contraction;neurological system process;MAPKKK cascade;calcium-mediated signa
                                             microtubule                non-motor microtubule binding protein
             cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;cellular component morpho
                                             morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             apoptosis;cellular component microtubule                   non-motor microtubule binding protein
             protein amino acid phosphorylation                         non-receptor serine/threonine protein kinase;non-receptor se
             protein amino acid phosphorylation                         non-receptor serine/threonine protein kinase;non-receptor se
             DNA repair                                                 methyltransferase;nuclease
             cell cycle;cell cycle                                      receptor


 uppressed because it is now thought that this gene does encode a protein.
ecause currently there is support for the transcript but not for the protein.
sequence does not appear to represent a valid product.

d genome annotation processing.

             transport                                                   transporter
             regulation of transcription from RNA polymerase II promoterbasic helix-loop-helix transcription factor;nucleic acid bindin
             meiosis;DNA repair;meiosis                                  DNA binding protein
                                                                         methyltransferase;DNA binding protein
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin arc
                                                                         methyltransferase;DNA binding protein
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin arc
                                                                         reductase
             proteolysis                     extracellular matrix        metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                     extracellular matrix        metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                     extracellular matrix        metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                     extracellular matrix        metalloprotease;metalloprotease;extracellular matrix protein
             meiosis;meiosis                                             structural protein
             immune system process                                       defense/immunity protein
             acyl-CoA metabolic process;acyl-CoA metabolic process acyltransferase
                                             cell junction               nucleotide kinase;protein kinase;nucleotide kinase;protein k
             neurotransmitter secretion;signal transduction;synaptic transmission;protein amino acid phosphorylation;signal transdu
             translation                                                 ribosomal protein

             translation                                                 ribosomal protein
uent of ribosome;nucleic acid binding                                    ribosomal protein
             translation                                                 ribosomal protein
             translation                                                 ribosomal protein
             translation                                                 ribosomal protein
             translation                                                 ribosomal protein
             translation                                                 ribosomal protein
             translation                                                 ribosomal protein
             regulation of transcription from RNA polymerase II promotertranscription cofactor;enzyme modulator
                                                                           transduction;cell surface receptor linked signal transductio
             B cell mediated immunity;cell surface receptor linked signalreceptor
             meiosis;DNA repair;meiosis                                  damaged DNA-binding protein
                                             actin cytoskeleton          actin family cytoskeletal protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                         reductase
             immune system process;protein modification process;response to stress
                                                                         homeobox development;skeletal system development
             regulation of transcription from RNA polymerase II promoter;mesodermtranscription factor;DNA binding protein
                                             mitochondrion;organelle     dehydrogenase;ligase;hydrolase
             purine base metabolic process;cellular amino acid biosynthetic process
                                                                         phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process
             translation                                                 translation release factor

                                                                            kinase;kinase
             cholesterol metabolic process;protein amino acid phosphorylation
                                                                            basic helix-loop-helix II promoter;cell cycle
             induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase transcription factor;nucleic acid bindin
                                            actin cytoskeleton              actin binding motor morphogenesis;cellular component mor
             muscle contraction;mitosis;cytokinesis;cell motion;mitosis;cellular component protein
                                            actin cytoskeleton              actin binding motor protein
             cell motion;cellular component morphogenesis;cellular component morphogenesis;mesoderm development;cellular com
             muscle contraction             actin cytoskeleton              actin family cytoskeletal protein;calmodulin
                                            actin cytoskeleton              actin family
             muscle contraction;mesoderm development;muscle organ development cytoskeletal protein;calmodulin
             muscle contraction;protein amino acid phosphorylation          non-receptor serine/threonine protein kinase;non-receptor se
                                            extracellular matrix;actin component morphogenesis;cellular component morphogenesis;
                                                                            extracellular matrix protein;actin family cytoskeletal protein
             muscle contraction;cell adhesion;cell adhesion;cellular cytoskeleton
             proteolysis                                                    protease;protease
             immune system process;induction of apoptosis
             immune system process;induction of apoptosis

NBPF14;ortholog
                                                                   immunoglobulin receptor of apoptosis;cell cycle;cell surface
            immune system process;muscle contraction;neurological system process;induction superfamily;protein phosphatase;p
            nuclear mRNA splicing, via spliceosome                 mRNA splicing factor
            immune response;response to stimulus                   oxidase

                                                                        receptor
             regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

                                                                       transferase
           immune system process;signal transduction;sulfur metabolic process;polysaccharide metabolic process;protein modifi
           respiratory electron transport chain;protein folding
complex subunit 6;NDUFB6;ortholog
           transport                                                   ATP-binding cassette (ABC) transporter
                                                                       ubiquitin-protein ligase
           gamete generation;cell motion;ectoderm development;nervous system development
                                                                       basic helix-loop-helix transcription factor;nuclease
           regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                           actin cytoskeleton          actin family cytoskeletal protein
           cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                        to stress
           immune system process;mesoderm development;response transcription factor
                                                                        to stress
           immune system process;mesoderm development;response transcription factor
           transcription from RNA polymerase II promoter               transcription factor;nucleic acid binding
           regulation of transcription from RNA polymerase II promoter
                                            adhesion;cell adhesion
           female gamete generation;cellextracellular matrix           receptor;extracellular matrix glycoprotein

 homolog;NIP7;ortholog
                                                                           metalloprotease;metalloprotease
            intracellular protein transport;proteolysis;mitochondrial transport;mitochondrial transport
            pyrimidine base metabolic process                              nucleotide kinase;nucleotide kinase
                                            extracellular matrix
            mesoderm development;skeletal system development               signaling molecule;extracellular matrix protein

             rRNA metabolic process;translation                              ribosomal protein
             ectoderm development;nervous system development                 transcription factor
             proteolysis                                                     metalloprotease;metalloprotease
                                                                             nuclear II promoter;signal transduction
             signal transduction;regulation of transcription from RNA polymerasehormone receptor;receptor
                                                                             immunoglobulin receptor superfamily;protein phosphatase;p
             immune system process;muscle contraction;induction of apoptosis;cell cycle;cell surface receptor linked signal transd
                                                                              RNA polymerase II promoter;proteolysis
             intracellular protein transport;regulation of transcription fromtranscription cofactor;aspartic protease;aspartic protease
            mitosis;mitosis                                               membrane trafficking regulatory protein
            protein targeting;signal transduction;signal transduction     enzyme modulator
            rRNA metabolic process                                        methyltransferase;nucleic acid binding
                                            extracellular matrix           adhesion;cell-cell linker protein
            neurological system process;signal transduction;cell-matrixextracellular matrixadhesion;signal transduction;cell-matrix
                                             adhesion;signal transduction;cell-matrix adhesion;ectoderm development;nervous system
            signal transduction;cell-matrixextracellular matrix           extracellular matrix linker protein
            cellular calcium ion homeostasis                              nucleic acid binding;annexin;calmodulin
            phospholipid metabolic process                                phosphatase;phosphatase
AS4;ortholog
                                                                          nucleotidyltransferase;nucleic acid binding;defense/immuni
            response to interferon-gamma;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;response to stim
            apoptosis;metabolic process                                   enzyme modulator
            RNA elongation from RNA polymerase II promoter                transcription cofactor
                                                                          membrane-bound
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion signaling molecule;cell adhesion molecul
            regulation of transcription from RNA polymerase II promotertranscription factor
            oxidative phosphorylation;respiratory electron transport chaintransferase;oxidoreductase
                                                                          receptor
            neurological system process;cell surface receptor linked signal transduction;cell surface receptor linked signal transdu
                                                                          receptor
            neurological system process;cell surface receptor linked signal transduction;cell surface receptor linked signal transdu
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;ectoderm development;n
                                                                          hydrolase
            immune system process;cellular amino acid biosynthetic process;response to toxin




            cell cycle;DNA replication;cell cycle                        replication origin binding protein

            lipid transport;cholesterol metabolic process                transfer/carrier protein
            proteolysis                                                  metalloprotease;metalloprotease

                                                                       homeobox transcription factor;DNA binding protein
            regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
            mitosis;mitosis;chromosome segregation;sex determination   protease;nucleic acid binding;protease
            female gamete generation;fertilization;proteolysis         serine protease;serine protease
            mRNA polyadenylation

            signal transduction;signal transduction
            mitosis;mitosis                                              nucleotidyltransferase
                                            adhesion;proteolysis;signal transduction;cell-matrix adhesion protease inhibitor
            signal transduction;cell-matrixextracellular matrix          extracellular matrix protein;serine
            complement activation;proteolysis;response to stimulus       metalloprotease;metalloprotease;complement component
            signal transduction;signal transduction                      small GTPase


                                                                          serine/threonine protein kinase receptor;serine/threonine pro
eceptor protein kinase activity;transmembrane receptor protein serine/threonine kinase activity;transmembrane receptor protein kina
                                                                          homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
            ectoderm development;nervous system development
                                             extracellular matrix          signaling molecule;receptor;metalloprotease;serine proteas
            immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp
bunit 15;MED15;ortholog
            mitosis;protein amino acid phosphorylation;mitosis             non-receptor serine/threonine protein kinase;non-receptor se
            immune system process;cellular defense response
            immune system process;cellular defense response
                                                                           growth factor
            cell cycle;transmembrane receptor protein tyrosine kinase signaling pathway;calcium-mediated signaling;cell-cell signa
            intracellular signaling cascade;intracellular signaling cascade
            protein modification process;proteolysis;translation           transcription factor;metalloprotease;nucleic acid binding;me
            intracellular protein transport;peroxisomal transport
            glycolysis                                                     mutase
            intracellular protein transport;proteolysis                    transporter
            pentose-phosphate shunt                                        hydrolase
                                                                            process
            immune system process;apoptosis;carbohydrate metabolicsignaling molecule;receptor;defense/immunity protein
                                                                           cysteine protease;cysteine
            signal transduction;cell-cell signaling;proteolysis;signal transduction;cell-cell signaling protease
                                                                           RNA binding protein
                                                                           acetyltransferase;zinc finger transcription factor;chromatin/c
            induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;protein amino acid acetyla
            proteolysis                                                    ubiquitin-protein ligase
                                                                           dehydrogenase
            carbohydrate metabolic process;cellular amino acid biosynthetic process
                                                                           hydroxylase
            fatty acid metabolic process;ectoderm development;nervous system development
-like;PHYHIPL;ortholog
            spermatogenesis;fertilization;immune system process            defense/immunity protein
                                             vesicle coat
            intracellular protein transport;receptor-mediated endocytosis  vesicle coat protein

a;PILRB;ortholog
                                                                       RNA binding protein
            calcium-mediated signaling;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;calcium-mediated
            DNA recombination
            cation transport;endoderm development                      ion channel
                                                                       phospholipase
            signal transduction;phospholipid metabolic process;signal transduction
            phospholipid metabolic process                             phospholipase
            intracellular protein transport;endocytosis                receptor
            complement activation;proteolysis;response to stimulus     metalloprotease;metalloprotease;complement component

           transcription from RNA polymerase II promoter                 zinc finger transcription factor
G member 3;PLEKHG3;ortholog
                                                                         guanyl-nucleotide exchange factor
           neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein s
mall GTPase regulator activity;guanyl-nucleotide exchange factor activityguanyl-nucleotide exchange factor
                                                                         transfer/carrier protein
           immune system process;lipid transport;phospholipid metabolic process;blood coagulation
                                                                         process;response to stress;defense response to bacterium
           macrophage activation;lipid transport;cholesterol metabolic transfer/carrier protein;antibacterial response protein
n 1;PMAIP1;ortholog
           meiosis;DNA repair;meiosis                                    DNA binding protein
           fatty acid metabolic process                                  acyltransferase;phospholipase
           coenzyme metabolic process;fatty acid metabolic process oxidase
                                                                         DNA-directed DNA polymerase;exodeoxyribonuclease;nucl
           cell cycle;DNA recombination;DNA repair;DNA replication;cell cycle
            cell cycle;DNA replication;cell cycle                   transcription factor;DNA-directed DNA polymerase
                                          nucleus                   transcription factor;DNA-directed DNA polymerase;chromat
            regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcription from RNA polymerase
            general transcription from RNA polymerase II promoter   nucleotidyltransferase;DNA-directed RNA polymerase
e J4, pseudogene (POLR2J4), non-coding RNA

_HUMAN;ortholog
                                                                      signaling molecule;cell adhesion molecule
           visual perception;sensory perception;signal transduction;cell-matrix adhesion;signal transduction;cell-matrix adhesion;m
           regulation of transcription from RNA polymerase II promoterhomeobox transcription factor
                                                                      protein phosphatase;protein phosphatase;calcium-binding p
           immune system process;mitosis;meiosis;intracellular signaling cascade;regulation of carbohydrate metabolic process;
           protein targeting;cell adhesion;cell adhesion;ectoderm development;nervous system development
                                                                      protein phosphatase;protein phosphatase
           apoptosis;meiosis;glycogen metabolic process;mRNA processing;protein amino acid phosphorylation;meiosis
PP1R11;ortholog
           apoptosis
                                                                      signaling molecule;phosphatase inhibitor
           neurological system process;G-protein coupled receptor protein signaling pathway;intracellular signaling cascade;intrac
           mitosis;cell motion;mitosis microtubule                    phosphatase modulator;microtubule family cytoskeletal pro
                                                                      protein phosphatase;protein cascade
           intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling phosphatase
                                                                      protein phosphatase;protein phosphatase;calmodulin
           calcium-mediated signaling;protein modification process;calcium-mediated signaling
           protein amino acid lipidation                              esterase



             regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
                                                                        DNA binding protein
             amino acid transport;transcription from RNA polymerase II promoter;cellular amino acid metabolic process
                                                                        phosphatase;phosphatase
             G-protein coupled receptor protein signaling pathway;phosphate metabolic process;lipid metabolic process;G-protein co
                                                                        kinase modulator
             immune system process;gluconeogenesis;cholesterol metabolic process;protein amino acid phosphorylation;response
                                                                        non-receptor serine/threonine protein kinase;transfer/carrier
             calcium-mediated signaling;protein amino acid phosphorylation;calcium-mediated signaling
                                                                        non-receptor serine/threonine protein kinase;non-receptor se
             muscle contraction;neurological system process;mitosis;intracellular signaling cascade;protein amino acid phosphoryl
             spermatogenesis

                                                                        homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development

             lipid transport;lipid metabolic process                       enzyme modulator
             protein amino acid phosphorylation                            protein phosphatase;protein phosphatase
                                                                           protein phosphatase;protein phosphatase
             cell cycle;cell surface receptor linked signal transduction;intracellular signaling cascade;protein amino acid phosphoryl
                                                                           receptor;protein phosphatase;protein phosphatase
             cell cycle;transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell adhesion;protein amino acid pho
                                                                           receptor;protein phosphatase;protein phosphatase
             immune system process;signal transduction;cell-cell adhesion;protein amino acid phosphorylation;signal transduction;
                                                                           receptor;protein phosphatase;protein phosphatase
             protein amino acid phosphorylation;cellular glucose homeostasis
                                                                           receptor;protein phosphatase;protein phosphatase
             cell surface receptor linked signal transduction;cell-cell adhesion;protein amino acid phosphorylation;cell surface recep
                                                                           transcription repair;mitosis;chromosome
             mitosis;regulation of transcription from RNA polymerase II promoter;DNAfactor;nucleic acid binding segregation
             general transcription from RNA polymerase II promoter         transcription factor;DNA binding protein
             tRNA metabolic process                                        lyase
                                                                           receptor;defense/immunity protein
             immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                           peroxidase
             immune system process;oxygen and reactive oxygen species metabolic process
                                                                           transferase
             cellular amino acid biosynthetic process;protein modification process
             tRNA aminoacylation for protein translation                   transferase;ligase;hydrolase
                                                                           small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                           guanyl-nucleotide transduction;synaptic transmission
             neurological system process;signal transduction;synaptic transmission;signalexchange factor
                                                                           small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                           small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                           small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                           small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
             intracellular protein transport                               guanyl-nucleotide exchange factor
d genome annotation processing.
                                                                      DNA repair;DNA recombination;establishment or maintenan
           regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
           cell cycle;DNA repair;cell cycle                           kinase activator
                                                                      endodeoxyribonuclease;nuclease;hydrolase
           B cell mediated immunity;DNA recombination;response to stimulus

            proteolysis                                                   serine protease;serine protease
                                                                          receptor
            protein targeting;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling path
            intracellular protein transport;nuclear transport             transporter;transfer/carrier protein
            cell adhesion;cell adhesion                                   G-protein modulator
                                                                          guanyl-nucleotide exchange factor
            cell surface receptor linked signal transduction;MAPKKK cascade;MAPKKK cascade;cell surface receptor linked signa
            MAPKKK cascade;MAPKKK cascade                                 guanyl-nucleotide exchange factor
                                                                          guanyl-nucleotide protein tyrosine
            G-protein coupled receptor protein signaling pathway;transmembrane receptorexchange factor kinase signaling pathwa
            regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
            mRNA polyadenylation                                          nuclease
            mRNA processing                                               RNA binding protein
                                                                          RNA binding
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process protein
            mRNA processing                                               RNA binding protein
                                                                          signaling molecule
            intracellular signaling cascade;intracellular signaling cascade;ectoderm development

            calcium-mediated signaling;calcium-mediated signaling        calmodulin
            DNA metabolic process;RNA catabolic process                  DNA binding protein
            DNA metabolic process;RNA catabolic process                  DNA binding protein
            metabolic process                                            dehydrogenase;reductase



            cell cycle;DNA replication;cell cycle                        nucleotidyltransferase;DNA-directed DNA polymerase

             regulation of transcription from RNA polymerase II promotertranscription cofactor;nuclease
n 4;Rgag4;ortholog
                                                                        guanyl-nucleotide protein tyrosine
             G-protein coupled receptor protein signaling pathway;transmembrane receptorexchange factor kinase signaling pathwa


                                                                       G-protein modulator
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway;dorsal/ventra
            transport                                                  cation transporter
            transport                                                  cation transporter
                                                                       small GTPase
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway

            intracellular protein transport;endocytosis                membrane trafficking regulatory protein;guanyl-nucleotide e
            regulation of transcription from RNA polymerase II promoterzinc finger transcription factor
                                                                       non-receptor serine/threonine protein kinase;non-receptor se
            induction of apoptosis;JNK cascade;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;protein amino acid ph
            transcription from RNA polymerase II promoter              zinc finger transcription factor
            protein metabolic process                                  RNA binding protein;ubiquitin-protein ligase

            spermatogenesis                                                zinc finger transcription factor
                                                                           transcription cofactor;ubiquitin-protein metabolic process;in
            intracellular signaling cascade;regulation of transcription from RNA polymerase II promoter;proteinligase

            regulation of transcription from RNA polymerase II promoterzinc finger transcription factor
            transcription from RNA polymerase II promoter                transcription factor
            protein modification process                                 ubiquitin-protein ligase
                                                                         ubiquitin-protein ligase
            synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteol
            purine base metabolic process                                 nucleotide kinase;nucleotide kinase
                                                                          non-receptor serine/threonine protein
            cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade kinase;non-receptor se
                                                                          non-receptor serine/threonine protein
            cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade kinase;non-receptor se
                                             extracellular matrix         signaling molecule;receptor;metalloprotease;serine proteas
            immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp
                                                                          membrane traffic protein
            intracellular protein transport;ectoderm development;nervous system development
                                             extracellular matrix         receptor linked signal transduction
            cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
mall GTPase regulator activity                                            G-protein modulator
                                                                          transcription cofactor;DNA helicase;helicase
            regulation of transcription from RNA polymerase II promoter;mesoderm development;embryonic development
                                                                          ligand-gated ion channel;ligand-gated ion channel
            muscle contraction;cation transport;calcium-mediated signaling;calcium-mediated signaling
hosphatase regulator activity                                             phosphatase modulator
            intracellular protein transport;vesicle-mediated transport    small GTPase
ARG;ortholog
SH1;ortholog
            intracellular protein transport;exocytosis;endocytosis        transferase;transfer/carrier protein
            cell cycle;cell cycle
            neurological system process
                                                                          ion channel
            blood circulation;sensory perception of taste;cation transport;regulation of vasoconstriction
            metabolic process                                             transfer/carrier protein;dehydrogenase;reductase
            regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
                                             extracellular matrix         extracellular matrix glycoprotein
            visual perception;sensory perception;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;mesod
                                                                          transcription
            rRNA metabolic process;termination of RNA polymerase II transcription factor
                                             SNARE complex
            intracellular protein transport;exocytosis                    SNARE protein
                                                                          membrane-bound signaling molecule
            signal transduction;signal transduction;ectoderm development;mesoderm development;angiogenesis;nervous system d
                                                                          membrane-bound signaling molecule
            immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor p
                                                                           transduction;intracellular signaling cascade;cell surface rec
            immune system process;cell surface receptor linked signal membrane-bound signaling molecule

             immune system process;proteolysis;response to toxin          serine protease;serine protease
             proteolysis                                                  serine protease inhibitor
             proteolysis                                                  serine protease inhibitor
             proteolysis                                                  serine protease inhibitor
             proteolysis                                                  serine protease inhibitor
             proteolysis                                                  serine protease inhibitor
             proteolysis                                                  serine protease inhibitor
             cell cycle;cell cycle                                        transcription factor

                                                                           signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling

             nuclear mRNA splicing, via spliceosome                      mRNA splicing factor
             nuclear mRNA splicing, via spliceosome                      mRNA splicing factor
                                                                         non-receptor serine/threonine protein kinase;non-receptor se
             cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade;ectoderm development;
                                                                         phosphatase;phosphatase
             intracellular protein transport;transmembrane receptor protein tyrosine kinase signaling pathway;cytokine-mediated sig
                                                                         signaling molecule
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
             intracellular protein transport                             transfer/carrier protein



             protein metabolic process

                                                                       ubiquitin-protein ligase
             proteolysis;ectoderm development;nervous system development
                                                                       transduction;cell-cell adhesion;cell surface receptor linked
             immune system process;cell surface receptor linked signal membrane-bound signaling molecule;immunoglobulin recep
                                                                          transduction;cell-cell adhesion;cell surface receptor linked
            immune system process;cell surface receptor linked signal membrane-bound signaling molecule;immunoglobulin recep
            regulation of transcription from RNA polymerase II promotertranscription factor;chromatin/chromatin-binding protein;dea
            cell adhesion;cell adhesion                                  G-protein modulator
                                                                         chromatin/chromatin-binding protein;deacetylase
            regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture;es
            cation transport;anion transport                             cation transporter
            transport                                                    mitochondrial carrier protein;transfer/carrier protein
                                            mitochondrial inner membrane;organelle
                                                                         transporter
            anion transport;extracellular transport;sulfur metabolic process
                                                                         transporter
            anion transport;extracellular transport;sulfur metabolic process
            carbohydrate transport;carbohydrate metabolic process        carbohydrate transporter
            carbohydrate transport;carbohydrate metabolic process        carbohydrate transporter
                                                                         transporter
            nucleobase, nucleoside, nucleotide and nucleic acid transport;nucleobase, nucleoside, nucleotide and nucleic acid me
                                                                         transporter
            nucleobase, nucleoside, nucleotide and nucleic acid transport;nucleobase, nucleoside, nucleotide and nucleic acid me

             transport;lipid metabolic process                             transporter
nsporter 8;SLC38A8;ortholog
             ion transport                                                 transporter
             cation transport                                              transporter
             ion transport                                                 transporter
bunit 3;SLC43A1;ortholog
                                                                           transporter
             ion transport;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             cation transport                                              cation transporter
             transport;carbohydrate metabolic process                      carbohydrate transporter;cation transporter
                                                                           amino acid transporter;cation process
             cation transport;extracellular transport;amino acid transport;cellular amino acid metabolic transporter
             amino acid transport;cellular amino acid metabolic process amino acid transporter
             amino acid transport;cellular amino acid metabolic process amino acid transporter
             cation transport                                              cation transporter
             cation transport                                              cation transporter
                                             extracellular matrix          receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
             protein folding                                               chaperone
                                                                           DNA repair;DNA recombination;establishment or maintenan
             regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
                                                                           DNA repair;DNA recombination;establishment or maintenan
             regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
                                                                           chromatin/chromatin-binding maintenance of chromatin arc
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment orprotein
ory subunit 3A;SMEK1;ortholog
                                                                           oxidase;nucleic acid binding
             respiratory electron transport chain;induction of apoptosis;porphyrin metabolic process;cellular amino acid metabolic pr


            regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
            protein targeting;endocytosis                              membrane trafficking regulatory protein
            protein targeting;endocytosis                              membrane trafficking regulatory protein
            mesoderm development;skeletal system development           signaling molecule
                                                                       transcription
            immune system process;transcription from RNA polymerase II promoter cofactor;zinc finger transcription factor;DNA bi

            proteolysis                                                 serine protease;serine protease


                                        microtubule                hydrolase;non-motor microtubule binding protein
            proteolysis;ectoderm development;nervous system development

                                                                        enzyme modulator
            immune system process;proteolysis;blood coagulation         serine protease inhibitor

ng;protein binding;cysteine-type endopeptidase inhibitor activity      cysteine protease inhibitor;calcium-binding protein
                                                                       transcription factor;signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;MAPKKK cascade;transmembrane receptor protein
             extracellular transport                                        receptor
             complement activation;response to stimulus                     complement component
             cell surface receptor linked signal transduction;intracellular signaling cascade;intracellular signaling cascade;cell surfac
             protein targeting;vesicle-mediated transport;translation       membrane traffic protein;calcium-binding protein
             transcription from RNA polymerase II promoter                  transcription factor;nucleic acid binding
                                                                            protein kinase receptor
             transmembrane receptor protein tyrosine kinase signaling pathway;intracellular signaling cascade;transmembrane rece
                                                                            regulation of apoptosis;JAK-STAT cascade;regulation of tra
             immune response;negative regulation of apoptosis;negative transcription factor;nucleic acid binding

MAN;ortholog
             protein amino acid phosphorylation                            non-receptor serine/threonine protein kinase;non-receptor se
                                                                           protein
             phosphate metabolic process;protein amino acid phosphorylation kinase;protein kinase
             intracellular signaling cascade;intracellular signaling cascade;ectoderm development;nervous system development
uent of cytoskeleton                        cytoskeleton                   cytoskeletal protein

                                             SNARE complex
            intracellular protein transport;vesicle-mediated transport    SNARE protein
                                             SNARE protein                SNARE protein
            neurotransmitter secretion;intracellularcomplextransport;vesicle-mediated transport;synaptic transmission;synaptic tran
                                             SNARE complex                SNARE protein
            synaptic vesicle exocytosis;protein targeting;exocytosis;synaptic transmission;synaptic transmission
                                                                          protein phosphatase;protein phosphatase;kinase inhibitor
            immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                          protein phosphatase;protein phosphatase;kinase inhibitor
            immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                          transcription cofactor;DNA binding protein
            general transcription from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
                                                                          hydrolase
            sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
                                                                          transcription factor;nucleic RNA polymerase II promoter
            transcription initiation from RNA polymerase II promoter;regulation of transcription fromacid binding
            transcription from RNA polymerase II promoter                 transcription factor
                                                                          methyltransferase;DNA binding protein
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin arc
            carbohydrate transport;carbohydrate metabolic process         carbohydrate transporter
                                                                          cell adhesion molecule
            signal transduction;cell adhesion;signal transduction;cell adhesion
            nuclear mRNA splicing, via spliceosome                        mRNA processing factor;ribosomal protein
                                                                          membrane trafficking regulatory protein
            synaptic vesicle exocytosis;intracellular protein transport;exocytosis;synaptic transmission;synaptic transmission
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
 A polymerase I subunit B;TAF1B;ortholog

                                                                        transcription factor;nucleic acid binding
             regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;nervous sy
             RNA elongation from RNA polymerase II promoter             transcription factor
                                             protein complex
             RNA elongation from RNA polymerase II promoter;proteolysis enzyme modulator
             RNA elongation from RNA polymerase II promoter             transcription cofactor
             RNA elongation from RNA polymerase II promoter             transcription factor

                                                                      nuclease
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

             regulation of transcription from RNA polymerase II promotertranscription factor

             negative regulation of apoptosis
                                           actin cytoskeleton           non-motor actin
             signal transduction;cell motion;signal transduction;mesoderm development binding protein
                                                                        protein phosphatase;protein phosphatase
             immune system process;induction of apoptosis;cell cycle;signal transduction;cell adhesion;phospholipid metabolic pro
             meiosis;meiosis                                            nucleic acid binding
                                                                        non-receptor serine/threonine protein acid phosphorylation;
             gamete generation;signal transduction;cell adhesion;phosphate metabolic process;protein amino kinase;non-receptor se

             transport                                                   transfer/carrier protein;serine protease;serine protease
                                                                         transcription factor;nucleic acid
             apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle binding

                                                                           receptor linked
             cell surface receptor linked signal transduction;cell surface growth factor signal transduction
             protein modification process                                  acyltransferase
              protein modification process                                 acyltransferase
              DNA metabolic process                                        nucleic acid binding
                                                                           nuclear hormone receptor;receptor
              sensory perception;signal transduction;regulation of transcription from RNA polymerase II promoter;signal transduction
bunit 13-like;MED13L;ortholog
                                                                           transcription promoter;cell cycle
              cell cycle;DNA replication;transcription initiation from RNA polymerase IIfactor;receptor;DNA polymerase processivity fa
                                                                           receptor
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
ein 1;THSD1;ortholog
                                                                           nucleic acid
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process binding
                                                                           homeobox development;skeletal system development;hear
              regulation of transcription from RNA polymerase II promoter;mesodermtranscription factor;DNA binding protein
                                              tight junction               tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                           nucleotide kinase;nucleotide kinase
              purine base metabolic process;pyrimidine base metabolic process
              vitamin metabolic process;pentose-phosphate shunt            transketolase
              vitamin metabolic process;pentose-phosphate shunt            transketolase
              regulation of transcription from RNA polymerase II promotertranscription cofactor
                                              extracellular matrix         transporter;apolipoprotein;membrane-bound signaling molec
              immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp
                                              extracellular matrix         receptor;extracellular matrix protein
              cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;mesoderm de




            proteolysis                                                   serine protease;serine protease
            proteolysis                                                   serine protease;serine protease
                                            extracellular matrix
            mesoderm development;skeletal system development              extracellular matrix structural protein
                                                                          tumor necrosis factor receptor
            induction of apoptosis;cell surface receptor linked signal transduction;cell surfacereceptor linked signal transduction
                                            plasma membrane               tumor necrosis factor receptor
            B cell mediated immunity;cytokine-mediated signaling pathway;cytokine-mediated signaling pathway;response to stimu
                                                                          tumor necrosis factor receptor
            B cell mediated immunity;macrophage activation;induction of apoptosis;cytokine-mediated signaling pathway;JNK casc
                                                                           receptor
            immune system process;induction of apoptosis;cell surfacereceptor linked signal transduction;I-kappaB kinase/NF-kap
                                            actin cytoskeleton            non-motor actin binding protein
            muscle contraction;mesoderm development;muscle organ development
            protein targeting;nuclear transport                           transporter;transfer/carrier protein
            cell cycle;transmembrane receptor protein serine/threonine kinase signaling pathway;JNK cascade;cell cycle;transmem
                                            cytoskeleton
            intracellular protein transport;endocytosis                   signaling molecule;cytoskeletal protein

           intracellular protein transport;endocytosis                    transporter
                                                                          mitochondrial carrier protein;transfer/carrier protein
           intracellular protein transport mitochondrial inner membrane;organelle
                                                                          DNA topoisomerase
           cell cycle;DNA replication;general transcription from RNA polymerase II promoter;cell cycle
           apoptosis;cell cycle;cell cycle                                enzyme modulator
           apoptosis;carbohydrate metabolic process                       dehydrogenase;reductase
P53INP1;ortholog
                                                                          transcription factor
           induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;DNA repair;cell cycle


                                                                         kinase;kinase
                                                                         tyrosine protein kinase receptor;tyrosine protein kinase rece
            intracellular protein transport;nuclear transport;transmembrane receptor protein tyrosine kinase signaling pathway;prote
             immune system process           microtubule                    non-motor microtubule binding protein
             protein targeting;translation
ke protein;TRAPPC2L;ortholog
                                                                            ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteol
                                                                            ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;glycoge
                                                                            ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteol
                                             cytoskeleton                   signaling molecule;cytoskeletal protein
             intracellular protein transport;endocytosis;cell cycle;cell cycle;cellular component morphogenesis;cellular component m
             tRNA metabolic process                                         RNA methyltransferase;RNA binding protein
                                                                            ion channel
             visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
                                                                            ion channel
             visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
                                                                            zinc finger development;mesoderm development;heart deve
             regulation of transcription from RNA polymerase II promoter;endoderm transcription factor;nuclease
             spermatogenesis;negative regulation of apoptosis               chaperone


                                                                          membrane-bound
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion signaling molecule;cell adhesion molecul
                                                                          membrane-bound
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion signaling molecule;cell adhesion molecul

                                                                            transferase;transfer/carrier
             immune system process;anion transport;sulfur metabolic process;response to toxin protein
             apoptosis
             proteolysis                                                    protease;protease
                                                                            isomerase;chaperone
             immune system process;neurological system process;negative regulation of apoptosis;cell cycle;negative regulation of
                                             extracellular matrix;actin component morphogenesis;cellular component morphogenesis;
                                                                            extracellular matrix protein;actin family cytoskeletal protein
             muscle contraction;cell adhesion;cell adhesion;cellular cytoskeleton
             protein metabolic process       microtubule                    ligase;microtubule family cytoskeletal protein
                                             tubulin complex;tubulin complextubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;
                                             tubulin complex;tubulin complextubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;
                                             tubulin complex;tubulin complextubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;
             visual perception;sensory perception;ectoderm development;nervous system development
             protein modification process                                   glycosyltransferase
             regulation of transcription from RNA polymerase II promoterbasic helix-loop-helix transcription factor;nucleic acid bindin
             DNA metabolic process;pyrimidine base metabolic processmethyltransferase

                                                                      transfer/carrier protein;ligase
             intracellular signaling cascade;coenzyme metabolic process;protein modification process;proteolysis;intracellular signa
                                                                      transfer/carrier protein;ligase
             intracellular signaling cascade;coenzyme metabolic process;protein modification process;proteolysis;intracellular signa
             protein modification process                             ligase
             protein modification process                             ligase
             proteolysis                                              ubiquitin-protein ligase
             proteolysis
             mitosis;mitosis                                          membrane trafficking regulatory protein
                                                                      glycosyltransferase
             polysaccharide metabolic process;steroid metabolic process

            polysaccharide metabolic process;steroid metabolic process  glycosyltransferase
                                                                        zinc finger transcription factor
            nucleobase, nucleoside, nucleotide and nucleic acid transport;cell cycle;nucleobase, nucleoside, nucleotide and nucle
UIMC1;ortholog
                                                                        decarboxylase
                                                                        receptor
            apoptosis;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;ectoderm dev
            spermatogenesis;mitosis;mitosis                             DNA glycosylase;kinase activator

             pyrimidine base metabolic process                            phosphorylase
                                                                          process
             carbohydrate metabolic process;pyrimidine base metabolic glycosyltransferase;nucleotide kinase;nucleotide kinase
                                                                          reductase
             oxidative phosphorylation;respiratory electron transport chain
                                           mitochondrion;organelle        reductase
             oxidative phosphorylation;respiratory electron transport chain
                                                                          reductase
             oxidative phosphorylation;respiratory electron transport chain
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              gamete generation;proteolysis                                 cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              gamete generation;proteolysis                                 cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              proteolysis                                                   cysteine   protease;cysteine protease
              RNA catabolic process;proteolysis                             cysteine   protease;exoribonuclease;nuclease;esterase;cyste

             transcription initiation from RNA polymerase II promoter         transcription factor
             proteolysis                                                      ligase
                                               actin cytoskeleton             non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                               intermediate component morphogenesis;ectoderm development;cellular component morp
             cellular component morphogenesis;cellularfilament cytoskeleton   structural protein;intermediate filament
                                                                              hydrolase
             signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
                                                                              hydrolase
             signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
             lysosomal transport;intracellular protein transport
             intracellular protein transport vesicle coat                     vesicle coat protein
             intracellular protein transport                                  membrane traffic protein
             intracellular protein transport                                  membrane traffic protein
                                                                              immunoglobulin receptor superfamily;immunoglobulin recep
             natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stim
                                                                              receptor;defense/immunity protein
             immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                               extracellular matrix           extracellular matrix protein;cell adhesion molecule
             immune system process;sensory perception of sound;sensory perception;signal transduction;cell-cell adhesion;signal
                                               adhesion;cell adhesion;blood extracellular matrix glycoprotein
             immune system process;cell extracellular matrix                  coagulation
 iled-coil;WAC;ortholog
             meiosis;meiosis
             transcription from RNA polymerase II promoter
                                                                              signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                              signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                              signaling molecule
             G-protein coupled receptor protein signaling pathway;cell-cell signaling;G-protein coupled receptor protein signaling pat


              DNA repair                                                    damaged DNA-binding protein

             regulation of transcription from RNA polymerase II promotertranscription cofactor
             tRNA aminoacylation for protein translation                nucleic acid binding;aminoacyl-tRNA synthetase
             transcription from RNA polymerase II promoter              transcription factor;chromatin/chromatin-binding protein
             intracellular protein transport;vesicle-mediated transport
 YRDC;ortholog
             transcription initiation from RNA polymerase II promoter   transcription factor
             transcription from RNA polymerase II promoter              zinc finger transcription factor
                                                                        nucleic acid binding
                                                                        nucleic acid binding
HC12;ortholog

              regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
               transcription from RNA polymerase II promoter                zinc finger transcription factor
                                               endoplasmic reticulum;organelle
                                                                            metalloprotease;metalloprotease
               cell surface receptor linked signal transduction;proteolysis;cell surface receptor linked signal transduction
               regulation of transcription from RNA polymerase II promotertranscription cofactor
or activity;transcription factor activity                                   zinc finger transcription factor

               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
or activity;transcription factor activity                                  KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
                                                                           nucleic acid binding;G-protein modulator
               G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               mitosis;mitosis;chromosome segregation
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;nuclease
                                                                           KRAB II promoter
               spermatogenesis;regulation of transcription from RNA polymerase box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
or activity;transcription factor activity                                  KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
                                                                           zinc finger transcription factor
               transcription from RNA polymerase II promoter;cell motion;segment specification;dorsal/ventral axis specification
               ectoderm development;nervous system development
or activity;transcription factor activity                                  KRAB box transcription factor
or activity;transcription factor activity                                  KRAB box transcription factor
                                                                           transcription
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process factor;nuclease
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
or activity;transcription factor activity                                  KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
or activity;transcription factor activity                                  zinc finger transcription factor
             Pathway
ubule binding protein


sette (ABC) transporter
sette (ABC) transporter


 erine protease
 erine protease

             Axon guidance mediated by netrin->Actin binding LIM protein 1;;



ase;protein phosphatase



              Alzheimer disease-presenilin pathway->actin;;Nicotinic acetylcholine receptor signaling pathway->Actin;;Cytoskeletal r
              Alzheimer disease-presenilin pathway->actin;;Nicotinic acetylcholine receptor signaling pathway->Actin;;Cytoskeletal r
elated protein
              Integrin signalling pathway->alpha actinin;;
              Alzheimer disease-presenilin pathway->actin;;Cadherin signaling pathway->Filamentous F-actin;;Huntington disease->
              Huntington disease->Actin;;
              TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;
metalloprotease
              Adenine and hypoxanthine salvage pathway->Adenosine deaminase;;Adenine and hypoxanthine salvage pathway->Deo
metalloprotease
metalloprotease
metalloprotease
              Ornithine degradation->Ornithine decarboxylase;;
binding protein




             FAS signaling pathway->Poly(ADP-ribose) polymerase;;

eceptor regulatory/adaptor protein;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;immunoglobulin superf
se;glycosidase




             De novo purine biosynthesis->Adenylate kinase;;



             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde deh
             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde deh
            5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;
            Fructose galactose metabolism->Fructose bisphosphate aldolase;;Glycolysis->Aldolase;;;




ription factor;DNA binding protein
              N-acetylglucosamine metabolism->N-acetylglucosamine-6-phosphate deacetylase;;
              Purine metabolism->5'-AMP Deaminase;;




metalloprotease

            Angiogenesis->Adenomatous Polyposis of the Colon;;Wnt signaling pathway->Adenomatous Polyposis Coli;;;
erine protease
clease;exodeoxyribonuclease;nuclease




            Huntington disease->ADP-ribosylation factor;;Integrin signalling pathway->ADP ribosylation factor 1;;Integrin signalling
            Huntington disease->Arfaptin-2;;
            Integrin signalling pathway->Rho;;
            PDGF signaling pathway->GTPase-activating protein Rho;;Cytoskeletal regulation by Rho GTPase->Rho-GTPase-activ

            PDGF signaling pathway->GTPase-activating protein Rho;;
e;G-protein modulator
e;G-protein modulator

            Integrin signalling pathway->Arp2/3;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin relate
            Integrin signalling pathway->Arp2/3;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin relate
            Integrin signalling pathway->Arp2/3;;Huntington disease->Actin-related protein 2 and 3 complex;;Inflammation mediated




deacetylase;metalloprotease


            Ubiquitin proteasome pathway->26S proteasome;;
            Ubiquitin proteasome pathway->26S proteasome;;
            Apoptosis signaling pathway->Activating transcription factor;;

            p53 pathway feedback loops 2->ATM;;p53 pathway->Ataxia telangiectasia mutated (ATM) and Rad3-related (ATR);;;
r;ion channel;hydrolase


n channel;hydrolase
n channel;hydrolase

r;ion channel;hydrolase


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

             Angiogenesis->Axis inhibitor 1;;Wnt signaling pathway->Axin;;Wnt signaling pathway->Wnt Target Genes;;;;

or;nucleic acid binding

              Apoptosis signaling pathway->Bcl-2 antogonist/killer;;
ription factor;DNA binding protein
ription factor;DNA binding protein
              p53 pathway->BCL2-associated X protein;;Apoptosis signaling pathway->Bcl-2 associated x protein;;Huntington diseas

rix glycoprotein
              Nicotinic acetylcholine receptor signaling pathway->acetylcholinesterase;;Muscarinic acetylcholine receptor 2 and 4 sig




ular matrix protein


             Apoptosis signaling pathway->Bik-like killer protein;;Apoptosis signaling pathway->Bcl-2 interacting killer;;;
king regulatory protein
king regulatory protein



             TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;


             Apoptosis signaling pathway->Bcl-2 related ovarian killer;;

erine protease




eceptor regulatory/adaptor protein
ne/threonine protein kinase;non-receptor serine/threonine protein kinase

on factor;nuclease




            EGF receptor signaling pathway->phosphatidylinositol 3-kinase;;Insulin/IGF pathway-protein kinase B signaling cascad




ferase;RNA binding protein
erine protease;complement component
erine protease;complement component
binding protein



ase;protein phosphatase




           Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Calcium ion channel;;Metabotro
           5HT2 type receptor mediated signaling pathway->Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->Ca2+ c
cium channel;voltage-gated ion channel
cium channel;voltage-gated ion channel
cium channel;voltage-gated ion channel

              Ionotropic glutamate receptor pathway->stargazin;;
              Ionotropic glutamate receptor pathway->calcium/calmodulin-dependent protein kinase II;;Inflammation mediated by che
 ;antibacterial response protein
binding protein
 ptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis
intracellular signaling cascade;synaptic transmission;cell surface receptor linked signal transduction;intracellular signaling cascade
e;cysteine protease


atin-binding protein




             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;


             p53 pathway feedback loops 2->CYCLIN G;;p53 pathway->Cyclin G;;p53 pathway feedback loops 2->cyclin G;;;;


ctor;kinase activator
eceptor superfamily;immunoglobulin receptor superfamily;major histocompatibility complex antigen


king regulatory protein
              B cell activation->Ig-alpha;;
d signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily
ytoskeletal protein

ase;protein phosphatase
             p53 pathway->Cell division cycle 25C;;


             Integrin signalling pathway->Cell division cycle 42;;Huntington disease->Rac;;Axon guidance mediated by Slit/Robo->C
binding protein


             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase
ne/threonine protein kinase;non-receptor serine/threonine protein kinase

or;nucleic acid binding

 ng;G-protein modulator
 erine protease;complement component
             Cytoskeletal regulation by Rho GTPase->Cofilin;;


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

or;DNA-directed DNA polymerase;chromatin/chromatin-binding protein




 osphatase;kinase;protein phosphatase;calmodulin




d signaling molecule;receptor;defense/immunity protein
king regulatory protein
 erine protease
             De novo purine biosynthesis->Adenylate kinase;;De novo pyrmidine ribonucleotides biosythesis->Uridylate kinase;;Salv
             Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;

eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cel
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;Inflammation mediated by chemokine and cytokine signaling pathway->ExtraCel
               Integrin signalling pathway->Collagen;;Inflammation mediated by chemokine and cytokine signaling pathway->ExtraCel
               Integrin signalling pathway->Collagen;;
rix structural protein
               Adrenaline and noradrenaline biosynthesis->Catechol-O-Methyl Transferase;;


binding protein
binding protein
metalloprotease
              Plasminogen activating cascade->thrombin activatable fibrinolysis inhibitor;;
metalloprotease
 ular matrix protein
e;mRNA polyadenylation factor;nuclease
              Muscarinic acetylcholine receptor 2 and 4 signaling pathway->choline acetyltransferase;;
 ;acyltransferase
skeletal protein
              Angiogenesis->Crk oncogene;;Integrin signalling pathway->Crk;;;

             VEGF signaling pathway->Heat-Shock Protein 27;;Angiogenesis->Heat-Shock Protein 27;;;




skeletal protein


cription factor
               Alzheimer disease-presenilin pathway->alpha-catenin;;Cadherin signaling pathway->Alpha-catenin;;Wnt signaling pathw
               Cadherin signaling pathway->Delta-catenin;;
               De novo pyrmidine ribonucleotides biosythesis->CTP synthase;;
               De novo pyrmidine ribonucleotides biosythesis->CTP synthase;;
e;cysteine protease
binding protein

oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;ex


             Huntington disease->P53 tumor suppressor phosphoprotein;;



             Vitamin D metabolism and pathway->Vitamin D 1-alpha-hydroxylase;;Vitamin D metabolism and pathway->Vitamin D 2
             Vitamin D metabolism and pathway->Vitamin D 1-alpha-hydroxylase;;Vitamin D metabolism and pathway->Vitamin D 2
             Nicotine degradation->cytochrome P450 subfamily IIA polypeptide 6;;

             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;




ription factor;DNA binding protein
              Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase;non-motor microtubule binding protein


ng motor protein
nesis;cellular component morphogenesis;cellular component morphogenesis;response to stress
               Adrenaline and noradrenaline biosynthesis->Aromatic L-amino acid decarboxylase;;Dopamine receptor mediated signa
 ng;G-protein modulator
nslation initiation factor;helicase
 icase;hydrolase



nucleotide exchange factor

;intermediate filament


             Formyltetrahydroformate biosynthesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;Folate
 e;protease;protease




             Huntington disease->Postsynaptic density 95;;

 ription factor;DNA binding protein
ng protein;hydrolase




or;nucleic acid binding
             Huntington disease->Dynein complex;;
             Huntington disease->Dynein complex;;


GTPase;microtubule family cytoskeletal protein
 ferase;DNA binding protein
 ferase;DNA binding protein
 A polymerase
e exchange factor
e exchange factor

metalloprotease
             Axon guidance mediated by semaphorins->Collapsin response mediator protein;;Axon guidance mediated by semapho

             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Wnt signaling pathway->Dishevelled;;Alzheimer disease-presenilin pathway->Dishevelled;;Angiogenesis->Dishelvelled;
             Wnt signaling pathway->Dishevelled;;Alzheimer disease-presenilin pathway->Dishevelled;;Angiogenesis->Dishelvelled;

sine protein kinase;non-receptor serine/threonine protein kinase;non-receptor serine/threonine protein kinase;non-receptor tyrosine p
or;nucleic acid binding



             Wnt signaling pathway->NFAT Target Genes;;Endothelin signaling pathway->Big endothelin 1, 2, 3, and 4;;Endothelin

             Angiogenesis->Ephrin;;

cription factor;nucleic acid binding
 protein;G-protein modulator;calcium-binding protein




             PDGF signaling pathway->Ets;;
             Integrin signalling pathway->ELMO;;




hatase;nucleotide phosphatase;pyrophosphatase
hatase;nucleotide phosphatase;pyrophosphatase
atin-binding protein
protein;G-protein modulator;calcium-binding protein
clease;nuclease
clease;nuclease
nding protein;endodeoxyribonuclease;exodeoxyribonuclease;nuclease;hydrolase



 receptor;receptor;nucleic acid binding


nuclease;esterase
nuclease;hydrolase


ase;protein phosphatase
ase;protein phosphatase
ase;protein phosphatase
             Anandamide_degradation->Fatty acid amide hydrolase;;


;chromatin/chromatin-binding protein
methyltransferase;dehydrogenase;esterase
 e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin;calmodulin
 e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin
osphatase;carbohydrate phosphatase




d signaling molecule;cell adhesion molecule




 eceptor superfamily;immunoglobulin receptor superfamily


e exchange factor
            FGF signaling pathway->FGFR1-4;;Angiogenesis->Fibroblast Growth Factor Receptor-1;;;

 inase receptor;tyrosine protein kinase receptor;protein kinase



 rone;calcium-binding protein




pt is a nonsense-mediated mRNA decay candidate.

 rted by current protein homology data.
              Nicotine degradation->Flavin-containing monooxygenase;;
              Nicotine degradation->Flavin-containing monooxygenase;;


              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
              Insulin/IGF pathway-protein kinase B   signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C


              Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor me
              Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor me

              Endothelin signaling pathway->Furin;;Alzheimer disease-amyloid secretase pathway->Furin;;Alzheimer disease-presen


 e;RNA binding protein
             EGF receptor signaling pathway->GRB2-associated binding protein;;
ubule binding protein
GABA receptor
GABA receptor
             p53 pathway->Growth arrest and DNA-damage-inducible, alpha;;p53 pathway->Growth arrest and DNA-damage-inducib

merase/racemase




 ription factor;nuclease



             TGF-beta signaling pathway->Transforming growth factor beta;;
G-protein modulator
 hosphodiesterase




channel;ligand-gated ion channel
              Blood coagulation->Glycoprotein 1bbeta;;Blood coagulation->Glycoprotein IX;;;




              Metabotropic glutamate receptor group III pathway->AMPA/Kainate Receptor;;Ionotropic glutamate receptor pathway->
              Ionotropic glutamate receptor pathway->Kainate Receptor;;Huntington disease->Kainate receptor;;Metabotropic glutam
              Metabotropic glutamate receptor group I pathway->N-methyl-D-aspartate Receptor;;Huntington disease->N-methyl-d-as


ation factor;translation release factor
               General transcription regulation->TFIIA;;Transcription regulation by bZIP transcription factor->TFIIA;;;
               General transcription regulation->General Transcription factor IIF, polypeptide 1, 74-KD;;Transcription regulation by bZIP
 tor;calmodulin

helix transcription factor;nucleic acid binding
rix glycoprotein



ing;deacetylase
ing;deacetylase




              Notch signaling pathway->Enhancer of Split complex genes;;
              Notch signaling pathway->Enhancer of Split complex genes;;

hatase;nucleotide phosphatase


cription factor
atibility complex antigen
atibility complex antigen
 ription factor;DNA binding protein
 ription factor;DNA binding protein
               p53 pathway->High mobility group protein 1;;
               p53 pathway->High mobility group protein 1;;

or;nucleic acid binding


ription factor;DNA binding protein
ription factor;DNA binding protein
ription factor;DNA binding protein
ription factor;DNA binding protein
             Parkinson disease->Heat shock protein 70;;Apoptosis signaling pathway->Heat shock protein 70;;;




;extracellular matrix structural protein;cell adhesion molecule

atin-binding protein




             Inflammation mediated by chemokine and cytokine signaling pathway->Cytokine receptor;;
             Toll receptor signaling pathway->Gene trancription;;
             Interferon-gamma signaling pathway->Interferongamma;;Inflammation mediated by chemokine and cytokine signaling p

             p53 pathway by glucose deprivation->alpha4;;

             B cell activation->mIgM;;
             Interleukin signaling pathway->Receptor subunit alpha;;

             Interleukin signaling pathway->Interleukin;;
             Interleukin signaling pathway->Receptor subunit alpha;;

 eceptor superfamily;immunoglobulin receptor superfamily
binding protein
              TGF-beta signaling pathway->Transforming growth factor beta;;
              Inflammation mediated by chemokine and cytokine signaling pathway->SH2 domain-containing inositol 5-phosphatase;



eceptor superfamily;immunoglobulin receptor superfamily
or;nucleic acid binding
              Toll receptor signaling pathway->Interferon (INF) regulatory factor 3;;
ription factor;nucleic acid binding
              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;
              Integrin signalling pathway->Integrin alpha;;Integrin signalling pathway->Collagen;;;
              Integrin signalling pathway->Integrin alpha;;Inflammation mediated by chemokine and cytokine signaling pathway->Inte




;intermediate filament
binding protein
binding protein

assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
-gated ion channel;voltage-gated potassium channel;voltage-gated ion channel;cyclic nucleotide-gated ion channel
 tor;calcium-binding protein
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
              Muscarinic acetylcholine receptor 1 and 3 signaling pathway->KCNQ K(+) channel;;
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel


ne trafficking regulatory protein




channel;ligand-gated ion channel




ferase;DNA binding protein
 ng;G-protein modulator


ng motor protein
ng motor protein
ng motor protein
ng motor protein
ng motor protein
ng motor protein
eceptor superfamily;immunoglobulin receptor superfamily


             Alzheimer disease-amyloid secretase pathway->kinesin;;
binding protein
/immunity protein
e exchange factor

;intermediate filament
;intermediate filament
;intermediate filament
;intermediate filament
;intermediate filament
;intermediate filament

;intermediate filament

or;chromatin/chromatin-binding protein
             Oxidative stress response->elongation factor 2 kinase;;p38 MAPK pathway->elongation factor-2 kinase;;;
             Integrin signalling pathway->Laminin;;



ne/threonine protein kinase;non-receptor serine/threonine protein kinase

             Integrin signalling pathway->Src;;Parkinson disease->Rous sarcoma protein tyrosine kinase;;T cell activation->Lck;;;;

             Cadherin signaling pathway->Transcription factor 4/Lymphoid enhancer-binding factor;;Alzheimer disease-presenilin pat


skeletal protein
              FAS signaling pathway->Nuclear Lamin;;


             Notch signaling pathway->LNXp80;;
ocus is entirely composed of repetitive sequence.




            Plasminogen activating cascade->Plasminogen;;Plasminogen activating cascade->Plasmin;;;
            Angiogenesis->Paxillin;;VEGF signaling pathway->Paxillin;;;

ular matrix protein
ular matrix glycoprotein
ular matrix protein


            Alzheimer disease-presenilin pathway->LRP C-terminal fragment;;Alzheimer disease-presenilin pathway->Low-density




ular matrix protein
ular matrix protein
ular matrix protein

            Toll receptor signaling pathway->MD-2;;
e/immunity protein
              Apoptosis signaling pathway->Mitogen activated protein kinase activating death domain;;

              Nicotinic acetylcholine receptor signaling pathway->Myosin;;



ubule binding protein
             Alzheimer disease-amyloid secretase pathway->Mitogen activated protein kinase;;p38 MAPK pathway->p38-delta mito
             Alzheimer disease-amyloid secretase pathway->Mitogen activated protein kinase;;EGF receptor signaling pathway->p3
             PDGF signaling pathway->MAPKAPK2;;Angiogenesis->Mitogen-Activated Protein Kinase-Activating Protein Kinase-2 a
ubule binding protein
ubule binding protein
ne/threonine protein kinase;non-receptor serine/threonine protein kinase
ne/threonine protein kinase;non-receptor serine/threonine protein kinase




helix transcription factor;nucleic acid binding

e;DNA binding protein
e;DNA binding protein

              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Plasminogen activating cascade->Matrix metalloprotease 1;;Alzheimer disease-presenilin pathway->Matrix metalloprot



              Inflammation mediated by chemokine and cytokine signaling pathway->Calcium/calModulin-dependent Kinase II;;Parkin




ctor;enzyme modulator
 nding protein
skeletal protein

ription factor;DNA binding protein
              Formyltetrahydroformate biosynthesis->Methylenetetrahydrofolate dehydrogenase;;



              Cholesterol biosynthesis->Mevalonate kinase;;
              Wnt signaling pathway->Wnt Target Genes;;Oxidative stress response->v-myc myelocytomatosis viral oncogene homo
              Inflammation mediated by chemokine and cytokine signaling pathway->Myosin;;Wnt signaling pathway->NFAT Target
              Inflammation mediated by chemokine and cytokine signaling pathway->Myosin;;Nicotinic acetylcholine receptor signali
skeletal protein;calmodulin
skeletal protein;calmodulin
              Cytoskeletal regulation by Rho GTPase->Myosin light chain kinase;;Inflammation mediated by chemokine and cytokine
rix protein;actin family cytoskeletal protein;cell adhesion molecule




eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cel




sette (ABC) transporter
              Notch signaling pathway->Neuralized;;
helix transcription factor;nuclease
skeletal protein


or;nucleic acid binding
             Toll receptor signaling pathway->IkappaB;;Inflammation mediated by chemokine and cytokine signaling pathway->Nucl
ular matrix glycoprotein


metalloprotease
             De novo purine biosynthesis->GDP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dTDP kinase;;De no
e;extracellular matrix protein



metalloprotease
receptor;receptor
eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cel
ctor;aspartic protease;aspartic protease
king regulatory protein

e;nucleic acid binding
             Axon guidance mediated by netrin->Netrin;;Axon guidance mediated by Slit/Robo->Netrin;;;
             Axon guidance mediated by netrin->Netrin;;Integrin signalling pathway->Laminin;;Axon guidance mediated by Slit/Robo
ing;annexin;calmodulin


erase;nucleic acid binding;defense/immunity protein


d signaling molecule;cell adhesion molecule




binding protein


metalloprotease

ription factor;DNA binding protein
acid binding;protease
erine protease




rix protein;serine protease inhibitor
metalloprotease;complement component



protein kinase receptor;serine/threonine protein kinase receptor;protein kinase
 ription factor;DNA binding protein
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt    signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;

e;receptor;metalloprotease;serine protease;metalloprotease;serine protease;extracellular matrix protein;enzyme modulator;cell adh

ne/threonine protein kinase;non-receptor serine/threonine protein kinase


             PDGF signaling pathway->PDGF;;Angiogenesis->Platelet-Derived Growth Factor;;;

or;metalloprotease;nucleic acid binding;metalloprotease

             Glycolysis->Phosphoglyceromutase;;


e;receptor;defense/immunity protein
e;cysteine protease

 ;zinc finger transcription factor;chromatin/chromatin-binding protein

             Serine glycine biosynthesis->Phosphoglycerate dehydrogenase;;




metalloprotease;complement component



e exchange factor
e exchange factor

otein;antibacterial response protein


hospholipase
           Pyridoxal phosphate salvage pathway->Pyridoxine-5-phosphate oxidase;;Vitamin B6 metabolism->Pyridoxamine phosp
           DNA replication->Pol alpha;;
or;DNA-directed DNA polymerase
or;DNA-directed DNA polymerase;chromatin/chromatin-binding protein
            General transcription by RNA polymerase I->RNA Polymerase I Complex;;



le;cell adhesion molecule
 ription factor
ase;protein phosphatase;calcium-binding protein
system development
               Dopamine receptor mediated signaling pathway->Protein Phosphatase-1;;


 e;phosphatase inhibitor
dulator;microtubule family cytoskeletal protein
             FGF signaling pathway->protein phosphatase 2A;;EGF receptor signaling pathway->protein phosphatase 2A;;Wnt sign
             Wnt signaling pathway->Calcineurin;;




cription factor


              p53 pathway by glucose deprivation->AMP-activated protein kinase;;
              Wnt signaling pathway->Protein Kinase C;;Thyrotropin-releasing hormone receptor signaling pathway->PKC;;Alzheime
              Endothelin signaling pathway->protein kinase, cGMP-dependent;;


 ription factor;DNA binding protein


ase;protein phosphatase
ase;protein phosphatase
phosphatase;protein phosphatase
             JAK/STAT signaling pathway->protein-tyrosine phosphatase;;T cell activation->CD45;;B cell activation->CD45;;;;
phosphatase;protein phosphatase
phosphatase;protein phosphatase
or;nucleic acid binding
or;DNA binding protein

/immunity protein




e exchange factor




e exchange factor
clease;nuclease;hydrolase

erine protease

 er/carrier protein
               Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein
               Integrin signalling pathway->CRK SH3 domain-binding guanine nucleotide-releasing factor;;
e exchange factor
               Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Calcium and diacylglycerol-regu
cription factor




erase;DNA-directed DNA polymerase

ctor;nuclease

e exchange factor


             Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->Regulator of G-protein signaling;




king regulatory protein;guanyl-nucleotide exchange factor

             Apoptosis signaling pathway->Receptor interacting protein;;

ein;ubiquitin-protein ligase


ctor;ubiquitin-protein ligase
e;nucleotide kinase
             Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->90 kDa ribosomal protein S6 kinas
             Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->90 kDa ribosomal protein S6 kinas
 e;receptor;metalloprotease;serine protease;metalloprotease;serine protease;extracellular matrix protein;enzyme modulator;cell adh

 ular matrix protein

 ctor;DNA helicase;helicase
            Beta2 adrenergic receptor signaling pathway->ER-type Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->E




 er/carrier protein



 otein;dehydrogenase;reductase
 ription factor;DNA binding protein
rix glycoprotein
               General transcription by RNA polymerase I->PTRF;;

             Axon guidance mediated by semaphorins->Semaphorin 3A;;
             Axon guidance mediated by semaphorins->Semaphorin 4D;;
d signaling molecule

erine protease

              Blood coagulation->Antithrombin III;;
              Blood coagulation->heparin cofactor II;;




              Wnt signaling pathway->secreted frizzled-related protein;;Angiogenesis->Frizzled-Related Protein;;;



ne/threonine protein kinase;non-receptor serine/threonine protein kinase




             p53 pathway feedback loops 2->SIAH-1;;p53 pathway->Seven in absentia homolog 1;;Wnt signaling pathway->Seven in
d signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;cell adhesion molecule
d signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;cell adhesion molecule
             Huntington disease->Sin3A;;p53 pathway->Sin3;;;
             Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein
             p53 pathway->Sirtuin;;

rier protein;transfer/carrier protein




nsporter;cation transporter
              Adrenaline and noradrenaline biosynthesis->amine translocator;;




 ular matrix protein

             Wnt signaling pathway->Switched/Sucrose Non Fermentation;;
             Wnt signaling pathway->Switched/Sucrose Non Fermentation;;
             Wnt signaling pathway->Switched/Sucrose Non Fermentation;;




ription factor;DNA binding protein
king regulatory protein
king regulatory protein

 ctor;zinc finger transcription factor;DNA binding protein

             Vasopressin synthesis->Signal Peptidase;;Endothelin signaling pathway->signal peptidase;;;


otor microtubule binding protein




e inhibitor;calcium-binding protein
               FGF signaling pathway->sprouty;;EGF receptor signaling pathway->SPRY;;EGF receptor signaling pathway->sprouty;
e;intracellular signaling cascade;cell surface receptor linked signal transduction
 protein;calcium-binding protein
or;nucleic acid binding

             EGF receptor signaling pathway->signal transducer and activator of transcription;;p53 pathway feedback loops 2->Myc;


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

             Cytoskeletal regulation by Rho GTPase->Stathmin;;


             Parkinson disease->Syntaxin;;Adrenaline and noradrenaline biosynthesis->N-ethylmaleimide-sensitive factor attachme

            Thyrotropin-releasing hormone receptor signaling pathway->SNARE COMPLEX;;Muscarinic acetylcholine receptor 2 an
            Oxidative stress response->MAP Kinase Phosphatases;;
            Oxidative stress response->MAP Kinase Phosphatases;;
ctor;DNA binding protein

or;nucleic acid binding

e;DNA binding protein


g factor;ribosomal protein
              Synaptic_vesicle_trafficking->Synaptophysin;;



or;nucleic acid binding




              Apoptosis signaling pathway->Bax inhibitor-1;;
binding protein
ase;protein phosphatase

ne/threonine protein kinase;non-receptor serine/threonine protein kinase

otein;serine protease;serine protease
or;nucleic acid binding

             TGF-beta signaling pathway->Transforming growth factor beta;;
 receptor;receptor

or;receptor;DNA polymerase processivity factor



 ription factor;DNA binding protein

e;nucleotide kinase


               Wnt signaling pathway->Transducin-like Enhance of Split 1-3;;
               TGF-beta signaling pathway->Transforming growth factor beta;;
               Toll receptor signaling pathway->Toll-like receptor 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12;;
 ription factor;DNA binding protein




 erine protease
 erine protease
rix structural protein
               p53 pathway->KILLER/death receptor (DR)5;;Apoptosis signaling pathway->TRAIL-receptor;;;
actor receptor
               Apoptosis signaling pathway->Tumor necrosis factor receptor 1;;

binding protein
 er/carrier protein
 pathway;JNK cascade;cell cycle;transmembrane receptor protein serine/threonine kinase signaling pathway;JNK cascade
 le;cytoskeletal protein


rier protein;transfer/carrier protein
               DNA replication->DNA Topoisomerase;;

              Huntington disease->Tumor protein p53 inducible protein 3;;

              Huntington disease->P53 tumor suppressor phosphoprotein;;P53 pathway feedback loops 1->P53;;p53 pathway->p53;;


             Thiamine metabolism->Thiamine kinase;;
 inase receptor;tyrosine protein kinase receptor;protein kinase
ubule binding protein




le;cytoskeletal protein
ferase;RNA binding protein
              Alzheimer disease-presenilin pathway->Capacitative calcium channels;;
              Alzheimer disease-presenilin pathway->Capacitative calcium channels;;
ription factor;nuclease



d signaling molecule;cell adhesion molecule
d signaling molecule;cell adhesion molecule

 er/carrier protein



rix protein;actin family cytoskeletal protein;cell adhesion molecule
e family cytoskeletal protein



 development

helix transcription factor;nucleic acid binding
              Formyltetrahydroformate biosynthesis->Thymidylate synthase;;Formyltetrahydroformate biosynthesis->Dihydrofolate re


              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;Ubiquitin proteasome pathway->Ubiquitin activating enzym
              Ubiquitin proteasome pathway->Ubiquitin-conjugating enzyme E2;;Ubiquitin proteasome pathway->Ubiquitin protein liga

              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;

king regulatory protein
             Nicotine degradation->UDP glycosyltransferase 2, member B7;;Nicotine degradation->UDP glycosytransferase 1, polyp

              Nicotine degradation->UDP glycosyltransferase 2, member B7;;Nicotine degradation->UDP glycosytransferase 1, polyp


              De novo pyrmidine ribonucleotides biosythesis->Orotidine-5-phosphate decarboxylase;;De novo pyrmidine ribonucleotid
              Axon guidance mediated by netrin->UNC-5;;
 ;kinase activator

              Salvage pyrimidine ribonucleotides->Uridine phosphorylase;;
              Salvage pyrimidine ribonucleotides->Uracil phosphoribosyltransferase;;
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;exoribonuclease;nuclease;esterase;cysteine protease


              Hypoxia response via HIF activation->Von Hippel Lindau protein;;
binding protein
;intermediate filament




eceptor superfamily;immunoglobulin receptor superfamily
/immunity protein
rix protein;cell adhesion molecule
              Blood coagulation->von Willebrand Factor;;Inflammation mediated by chemokine and cytokine signaling pathway->Extr



             Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Angiogenesis->Wingless-Type MM
             Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathw
             Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathw


nding protein


ing;aminoacyl-tRNA synthetase
or;chromatin/chromatin-binding protein




ription factor;DNA binding protein
metalloprotease



 ription factor;DNA binding protein
cription factor
cription factor
 ription factor;DNA binding protein
 ription factor;DNA binding protein
 ng;G-protein modulator
cription factor

cription factor
 ription factor;nuclease
cription factor;nucleic acid binding
cription factor
cription factor
cription factor
cription factor
cription factor
cription factor
cription factor
cription factor


cription factor
cription factor

cription factor
cription factor;nucleic acid binding
cription factor
cription factor;nucleic acid binding
 ription factor;DNA binding protein
cription factor
cription factor
cription factor
cription factor
hway->Actin;;Cytoskeletal regulation by Rho GTPase->Actin;;Wnt signaling pathway->NFAT Target Genes;;Cadherin signaling path
hway->Actin;;Cytoskeletal regulation by Rho GTPase->Actin;;Wnt signaling pathway->NFAT Target Genes;;Cadherin signaling path


actin;;Huntington disease->Actin;;;;

ceptors;;;

hine salvage pathway->Deoxyadenosine deaminase;;;




mily;immunoglobulin superfamily cell adhesion molecule




n->Phenylacetaldehyde dehydrogenase;;;
n->Phenylacetaldehyde dehydrogenase;;;
s Polyposis Coli;;;




factor 1;;Integrin signalling pathway->ADP ribosylation factor 6;;;;


TPase->Rho-GTPase-activating proteins;;Angiogenesis->Rho GTPase;;VEGF signaling pathway->Rho GTPase;;;;;




naling pathway->Actin related protein 2/3 complex;;Cytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;
naling pathway->Actin related protein 2/3 complex;;Cytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;
plex;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin related protein 2/3 complex;;Cytoskeletal regulat




nd Rad3-related (ATR);;;
 Target Genes;;;;




x protein;;Huntington disease->Bcl-2-associated X protein;;;;


choline receptor 2 and 4 signaling pathway->acetylcholinesterase;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->a




eracting killer;;;




ceptors;;;
kinase B signaling cascade->Phosphatidylinositol 3-kinase;;PDGF signaling pathway->PHOSPHATIDYLINOSITOL 3-KINASE, CAT
ium ion channel;;Metabotropic glutamate receptor group III pathway->Calcium Channel;;Thyrotropin-releasing hormone receptor sign
signaling pathway->Ca2+ channel;;Alzheimer disease-amyloid secretase pathway->L-type calcium channels;;Nicotinic acetylcholin




ammation mediated by chemokine and cytokine signaling pathway->Calcium/calModulin-dependent Kinase II;;;
acellular signaling cascade;synaptic transmission




loops 2->cyclin G;;;;




e mediated by Slit/Robo->Cell division cycle 42;;T cell activation->cdc42;;EGF receptor signaling pathway->Rac;;p38 MAPK pathwa
esis->Uridylate kinase;;Salvage pyrimidine ribonucleotides->Cytidylate kinase;;;;
ted ion channel;;

unoglobulin superfamily cell adhesion molecule




gnaling pathway->ExtraCellular matrix protein;;;
gnaling pathway->ExtraCellular matrix protein;;;
atenin;;Wnt signaling pathway->alpha-Catenin;;;;




protease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule




 and pathway->Vitamin D 25-Hydroxylase;;;
 and pathway->Vitamin D 25-Hydroxylase;;;




rotein




ne receptor mediated signaling pathway->Aromatic L-amino acid decarboxylase;;Histamine synthesis->Histidine Decarboxylase;;5-H
drofolate reductase;;Folate biosynthesis->Dihydrofolate synthase;;;;




ance mediated by semaphorins->CRMP 3-associated molecule;;Pyrimidine Metabolism->Dihydropyrimidinase;;;;




ngiogenesis->Dishelvelled;;;;
ngiogenesis->Dishelvelled;;;;

ase;non-receptor tyrosine protein kinase
1, 2, 3, and 4;;Endothelin signaling pathway->Pre-pro endothelin 1, 2, 3, and 4;;Endothelin signaling pathway->Pro endothelin 1, 2,
calmodulin
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3


e 1;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signalin
e 1;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signalin

;;Alzheimer disease-presenilin pathway->Furin;;;;




st and DNA-damage-inducible, alpha;;;
tamate receptor pathway->Glutamate receptor, ionotropic, AMPA 1;;Ionotropic glutamate receptor pathway->AMPA Receptor;;Ionot
eptor;;Metabotropic glutamate receptor group III pathway->AMPA/Kainate Receptor;;Ionotropic glutamate receptor pathway->glutam
on disease->N-methyl-d-aspartate receptor;;Ionotropic glutamate receptor pathway->NR3;;Metabotropic glutamate receptor group III



>TFIIA;;;
nscription regulation by bZIP transcription factor->General transcription factor IIF, polypeptide 1, 74-KD;;;
ein 70;;;




ne and cytokine signaling pathway->Interferon gamma;;;




 ing inositol 5-phosphatase;;PI3 kinase pathway->SHIP;;Insulin/IGF pathway-protein kinase B signaling cascade->SH2 domain-cont




ine signaling pathway->Integrin;;;
n channel
or-2 kinase;;;




;;T cell activation->Lck;;;;

imer disease-presenilin pathway->T-cell factor/lymphoid enhancer factor;;Wnt signaling pathway->T cell factor;;;;
;;;




nilin pathway->Low-density lipoprotein receptor-related protein;;Alzheimer disease-presenilin pathway->LRP N-terminal fragment;;Alz
 K pathway->p38-delta mitogen-activated protein kinase;;EGF receptor signaling pathway->p38 MAP kinase;;Oxidative stress respo
eptor signaling pathway->p38 MAP kinase;;Oxidative stress response->p38 MAP Kinase;;B cell activation->p38;;Parkinson disease
 ctivating Protein Kinase-2 and 3;;Interleukin signaling pathway->Mitogen-activated protein kinase-activated protein kinase 2;;VEGF




athway->Matrix metalloprotease;;Plasminogen activating cascade->pro-Matrix metalloprotease 1;;Plasminogen activating cascade->



dependent Kinase II;;Parkinson disease->Calcium/calmodulin-dependent serine protein kinase;;;
atosis viral oncogene homolog;;p53 pathway feedback loops 2->Myc;;Interleukin signaling pathway->c-Myc;;PDGF signaling pathw
ng pathway->NFAT Target Genes;;Nicotinic acetylcholine receptor signaling pathway->Myosin;;Cytoskeletal regulation by Rho GTP
etylcholine receptor signaling pathway->Myosin;;Cytoskeletal regulation by Rho GTPase->Myosin light chain;;;;


by chemokine and cytokine signaling pathway->Myosin light chain kinase;;;




unoglobulin superfamily cell adhesion molecule




ne signaling pathway->Nuclear factor kappa-B;;;




hesis->dTDP kinase;;De novo purine biosynthesis->dADP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dCDP kina




unoglobulin superfamily cell adhesion molecule
ance mediated by Slit/Robo->Netrin;;;;
enzyme modulator;cell adhesion molecule




olism->Pyridoxamine phosphate oxidase;;PLP biosynthesis->Pyridoxine-5-phosphate oxidase;;Pyridoxal phosphate salvage pathwa
phosphatase 2A;;Wnt signaling pathway->Protein phosphatase 2A;;;;




pathway->PKC;;Alzheimer disease-amyloid secretase pathway->Protein kinase C;;EGF receptor signaling pathway->PKC;;Histam




activation->CD45;;;;
1 GTPase-activating protein 1;;


ium and diacylglycerol-regulated guanine nucleotide exchange factor;;




lator of G-protein signaling;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Regulator of G-p
 ribosomal protein S6 kinase;;PDGF signaling pathway->p90RSK;;p53 pathway by glucose deprivation->S6K;;PI3 kinase pathway->
 ribosomal protein S6 kinase;;PDGF signaling pathway->p90RSK;;p53 pathway by glucose deprivation->S6K;;PI3 kinase pathway->
enzyme modulator;cell adhesion molecule




eptor signaling pathway->ER-type Ca2+ channel;;;




rotein;;;




ignaling pathway->Seven in absentia homolog 1;;p53 pathway feedback loops 2->SIAH-1;;;;;
sion molecule
sion molecule

1 GTPase-activating protein 1;;




;;




gnaling pathway->sprouty;;;;
ay feedback loops 2->Myc;;Oxidative stress response->v-myc myelocytomatosis viral oncogene homolog;;Angiogenesis->Signal Tr




e-sensitive factor attachment protein receptor;;;

acetylcholine receptor 2 and 4 signaling pathway->N-ethylmaleimide-sensitive factor attachment protein receptor;;Dopamine recepto
;;




way;JNK cascade




->P53;;p53 pathway->p53;;p53 pathway by glucose deprivation->p53;;P53 pathway feedback loops 1->Delta Np73;;p53 pathway fee
synthesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;De novo pyrimidine deoxyribonucleotide biosynth


>Ubiquitin activating enzyme E1;;;
 hway->Ubiquitin protein ligase E3;;;




glycosytransferase 1, polypeptide A4;;;

glycosytransferase 1, polypeptide A4;;;


ovo pyrmidine ribonucleotides biosythesis->Orotate phosphoribosyltransferase;;;
ne signaling pathway->ExtraCellular matrix protein;;;



nesis->Wingless-Type MMTV Integration Site Family;;Alzheimer disease-presenilin pathway->Wingless-type protein;;Wnt signaling
er disease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family membe
er disease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family membe
es;;Cadherin signaling pathway->Filamentous F-actin;;Integrin signalling pathway->Actin;;Inflammation mediated by chemokine and
es;;Cadherin signaling pathway->Filamentous F-actin;;Integrin signalling pathway->Actin;;Inflammation mediated by chemokine and
GTPase;;;;;




d protein 2/3 complex;;;;
d protein 2/3 complex;;;;
mplex;;Cytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;;
nd 3 signaling pathway->acetylcholinesterase;;;;
LINOSITOL 3-KINASE, CATALYTIC, ALPHA;;PI3 kinase pathway->p101;;p53 pathway feedback loops 2->PI3K;;p53 pathway->PI3-
sing hormone receptor signaling pathway->Ca2+ channel;;Endogenous_cannabinoid_signaling->Voltage-dependent Ca channel;;Me
nels;;Nicotinic acetylcholine receptor signaling pathway->Calcium Channel;;Oxytocin receptor mediated signaling pathway->Ca2+ c




se II;;;
y->Rac;;p38 MAPK pathway->cell division cycle 42;;Inflammation mediated by chemokine and cytokine signaling pathway->Cell div
istidine Decarboxylase;;5-Hydroxytryptamine biosynthesis->Aromatic L-amino acid decarboxylase;;;;;
nase;;;;
hway->Pro endothelin 1, 2, 3, and 4;;Endothelin signaling pathway->Endothelin 1, 2, 3, and 4;;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;


e receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;
e receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;
ay->AMPA Receptor;;Ionotropic glutamate receptor pathway->AMPA/Kainate Receptor;;;;;
e receptor pathway->glutamate receptor, ionotropic, kainate 4;;Ionotropic glutamate receptor pathway->AMPA/Kainate Receptor;;;;;;
glutamate receptor group III pathway->N-methyl-D-aspartate Receptor;;Ionotropic glutamate receptor pathway->N-methyl-D-aspartate
ascade->SH2 domain-containing inositol 5-phosphatase 2;;;;
factor;;;;
RP N-terminal fragment;;Alzheimer disease-presenilin pathway->LRP intracellular fragment;;Alzheimer disease-presenilin pathway->L
 se;;Oxidative stress response->p38 MAP Kinase;;B cell activation->p38;;Ras Pathway->p38 mitogen activated protein kinase;;p53
n->p38;;Parkinson disease->p38 MAPK;;Ras Pathway->p38 mitogen activated protein kinase;;p53 pathway feedback loops 2->p38
ed protein kinase 2;;VEGF signaling pathway->Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 and 3;;Ras Pathway->M




nogen activating cascade->Matrix metalloprotease 13;;Plasminogen activating cascade->pro-matrix metalloprotease 13;;;;;;
 yc;;PDGF signaling pathway->c-Myc;;;;;;
etal regulation by Rho GTPase->Myosin light chain;;;;;
chain;;;;




e biosynthesis->dCDP kinase;;De novo pyrmidine ribonucleotides biosythesis->UDP kinase;;De novo pyrmidine ribonucleotides bio
phosphate salvage pathway->Pyridoxamine-5-phosphate oxidase;;;;;
ng pathway->PKC;;Histamine H1 receptor mediated signaling pathway->PKC;;Muscarinic acetylcholine receptor 1 and 3 signaling
pathway->Regulator of G-protein signaling;;;
S6K;;PI3 kinase pathway->S6K;;;;;
S6K;;PI3 kinase pathway->S6K;;;;;
g;;Angiogenesis->Signal Transducer and Activator of Transcription 1;;PDGF signaling pathway->STAT;;Ras Pathway->Signal transd




receptor;;Dopamine receptor mediated signaling pathway->SNARE Complex;;Opioid proopiomelanocortin pathway->SNARE COMP
elta Np73;;p53 pathway feedback loops 2->p53;;p53 pathway->p53;;P53 pathway feedback loops 1->P73DeltaN;;;;;;;;;
eoxyribonucleotide biosynthesis->Thymidylate synthase;;Folate biosynthesis->Dihydrofolate synthase;;;;;;
type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;;
egration site family member;;;;
egration site family member;;;;
ediated by chemokine and cytokine signaling pathway->F-actin;;Huntington disease->Actin;;;;;;;;;
ediated by chemokine and cytokine signaling pathway->F-actin;;Huntington disease->Actin;;;;;;;;;
>PI3K;;p53 pathway->PI3-K;;Axon guidance mediated by netrin->Phosphotidylinositol 3-kinase;;Endothelin signaling pathway->pho
dependent Ca channel;;Metabotropic glutamate receptor group II pathway->Calcium Channel;;Ionotropic glutamate receptor pathway
signaling pathway->Ca2+ channel;;Beta2 adrenergic receptor signaling pathway->Ca2+ channel;;;;;;;
signaling pathway->Cell division cycle 42;;TGF-beta signaling pathway->Ras-GTP;;Cytoskeletal regulation by Rho GTPase->Cell div
MPA/Kainate Receptor;;;;;;
way->N-methyl-D-aspartate Receptor;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->N-methyl-D-aspartate Recepto
ease-presenilin pathway->LRP transmembrane fragment;;Wnt signaling pathway->Low density lipoprotein receptor related protein;;;
tivated protein kinase;;p53 pathway feedback loops 2->p38 MAPK;;Interferon-gamma signaling pathway->Serine kinase;;TGF-beta s
 ay feedback loops 2->p38 MAPK;;JAK/STAT signaling pathway->Serine kinase;;p38 MAPK pathway->p38-alpha mitogen-activated
e 2 and 3;;Ras Pathway->Mitogen activated protein kinase activated protein kinase;;p38 MAPK pathway->MAPK-activated protein k




alloprotease 13;;;;;;
midine ribonucleotides biosythesis->CDP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dUDP kinase;;De novo pu
receptor 1 and 3 signaling pathway->Protein kinase C;;VEGF signaling pathway->Protein Kinase C;;Angiogenesis->Protein Kinase
as Pathway->Signal transducer and activator of transcription;;Interleukin signaling pathway->Signal transducers and activators of tra




n pathway->SNARE COMPLEX;;Nicotinic acetylcholine receptor signaling pathway->N-ethylmaleimide-sensitive factor attachment p
3DeltaN;;;;;;;;;
;;
lin signaling pathway->phosphatidylinositol 3-kinase;;;;;;;;;
glutamate receptor pathway->Calcium Channel;;GABA-B_receptor_II_signaling->Voltage-dependent Ca channel;;;;;;;;
n by Rho GTPase->Cell division cycle 42;;Axon guidance mediated by netrin->Cell division cycle 42;;TGF-beta signaling pathway->R
methyl-D-aspartate Receptor;;;;;;;
n receptor related protein;;;;;;;
>Serine kinase;;TGF-beta signaling pathway->P38;;FGF signaling pathway->p38 MAP kinase;;Integrin signalling pathway->Extracel
38-alpha mitogen-activated protein kinase;;Interferon-gamma signaling pathway->Serine kinase;;TGF-beta signaling pathway->P38;;T
>MAPK-activated protein kinase 2;;;;;;;
>dUDP kinase;;De novo purine biosynthesis->dGDP kinase;;;;;;;;;
ogenesis->Protein Kinase C;;FGF signaling pathway->PKC;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha me
ducers and activators of transcription;;Interferon-gamma signaling pathway->Signal transducers and activaotrs of transcription 1;;Oxi




nsitive factor attachment protein receptor;;Cortocotropin releasing factor receptor signaling pathway->SNARE COMPLEX;;5HT2 type
hannel;;;;;;;;
F-beta signaling pathway->Ras-GDP;;Ras Pathway->Cdc42;;;;;;;;;;;;;
gnalling pathway->Extracellular signal-regulated kinase;;;;;;;;;;;;
a signaling pathway->P38;;Toll receptor signaling pathway->p38;;VEGF signaling pathway->p38 Mitogen-Activated Protein Kinase;;F
Gq alpha and Go alpha mediated pathway->Protein kinase C;;Endothelin signaling pathway->protein kinase c;;Oxytocin receptor m
aotrs of transcription 1;;Oxidative stress response->signal transducer and activator of transcription 1;;JAK/STAT signaling pathway->




ARE COMPLEX;;5HT2 type receptor mediated signaling pathway->SNARE Complex;;Beta3 adrenergic receptor signaling pathway-
Activated Protein Kinase;;FGF signaling pathway->p38 MAP kinase;;Angiogenesis->p38 Mitogen-Activated Protein Kinase;;;;;;;;;;;;;
ase c;;Oxytocin receptor mediated signaling pathway->PKC;;5HT2 type receptor mediated signaling pathway->PKC;;;;;;;;;;;;;;
K/STAT signaling pathway->Signal transducers and activators of transcription;;Inflammation mediated by chemokine and cytokine sig




eceptor signaling pathway->SNARE COMPLEX;;Opioid prodynorphin pathway->SNARE COMPLEX;;5HT1 type receptor mediated s
ed Protein Kinase;;;;;;;;;;;;;;;;
way->PKC;;;;;;;;;;;;;;
chemokine and cytokine signaling pathway->Signal transducers and activaotrs of transcription;;;;;;;;;;;;




1 type receptor mediated signaling pathway->SNARE Complex;;Opioid proenkephalin pathway->SNARE COMPLEX;;Oxytocin recep
COMPLEX;;Oxytocin receptor mediated signaling pathway->SNARE COMPLEX;;5HT4 type receptor mediated signaling pathway->
diated signaling pathway->SNARE Complex;;Beta2 adrenergic receptor signaling pathway->SNARE COMPLEX;;Beta1 adrenergic re
MPLEX;;Beta1 adrenergic receptor signaling pathway->SNARE COMPLEX;;5HT3 type receptor mediated signaling pathway->SNAR
signaling pathway->SNARE Complex;;;;;;;;;;;;;;;;;
Z value   Gene SymbolAccession   Gene Name                      GO Molecular Function
2.00      A2M        NM_000014                                  cytokine
                                 Alpha-2-macroglobulin;A2M;ortholog activity;serine-type endopeptidase
2.03      AASDH      NM_181806                                  ligase activity
                                 Acyl-CoA synthetase family member 4;AASDH;ortholog
2.24      ABCC2      NM_000392                                  ATPase transporter 1;ABCC2;ortholog
                                 Canalicular multispecific organic anionactivity, coupled to transmembrane
2.72      ABCC3      NM_003786                                  ATPase transporter 2;ABCC3;ortholog
                                 Canalicular multispecific organic anionactivity, coupled to transmembrane
-2.30     ABCC8      NM_000352                                  ATPase activity, member 8;ABCC8;ortholog
                                 ATP-binding cassette transporter sub-family C coupled to transmembrane
2.60      ABCD3      NM_002858                                  transmembrane transporter activity
                                 ATP-binding cassette sub-family D member 3;ABCD3;ortholog
2.30      ABCG2      NM_004827                                  transmembrane transporter activity
                                 ATP-binding cassette sub-family G member 2;ABCG2;ortholog
2.07      ACAD10     NM_025247                                  oxidoreductase activity;transferase
                                 Acyl-CoA dehydrogenase family member 10;ACAD10;ortholog activity
2.63      ACE2       NM_021804                                  metallopeptidase activity
                                 Processed angiotensin-converting enzyme 2;ACE2;ortholog
2.75      ACOX2      NM_003500                                  oxidoreductase activity
                                 Peroxisomal acyl-coenzyme A oxidase 2;ACOX2;ortholog
-2.67     ACP1       NM_004300                                  phosphoprotein phosphatase activity;phosph
                                 Low molecular weight phosphotyrosine protein phosphatase;ACP1;ortholo
-2.76     ACSF2      NM_025149                                  ligase activity
                                 Acyl-CoA synthetase family member 2, mitochondrial;ACSF2;ortholog
2.07      ACVR1C     NM_145259                                  transmembrane receptor protein kinase activ
                                 Activin receptor type-1C;ACVR1C;ortholog
-2.87     ACVR2      NM_001616                                  transmembrane receptor protein kinase activ
                                 Activin receptor type-2A;ACVR2A;ortholog
-4.45     ADAMTS20 NM_025003                                    metallopeptidase activity
                                 A disintegrin and metalloproteinase with thrombospondin motifs 20;ADAM
-3.05     ADC        NM_052998                                  carboxy-lyase activity
                                 Arginine decarboxylase;ADC;ortholog
-2.92     ADCY9      NM_001116                                  adenylate cyclase activity
                                 Adenylate cyclase type 9;ADCY9;ortholog
-2.44     ADSS       NM_001126                                   isozyme 2;ADSS;ortholog
                                 Adenylosuccinate synthetaseligase activity
2.12      AEGP       XM_088463   Apical endosomal glycoprotein;MAMDC4;ortholog
-2.61     AES        NM_001130                                  transcription factor
                                 Amino-terminal enhancer of split;AES;ortholog activity;transcription facto
-2.28     AFM        NM_001133   Afamin;AFM;ortholog
2.15      AFP        NM_001134   Alpha-fetoprotein;AFP;ortholog
2.69      AIFM3      NM_144704                                  oxidoreductase
                                 Apoptosis-inducing factor 3;AIFM3;ortholog activity
2.37      AKAP1      NM_003488                                  receptor binding
                                 A kinase anchor protein 1, mitochondrial;AKAP1;ortholog
2.79      AKAP10     NM_007202                                  protein binding;kinase activator
                                 A kinase anchor protein 10, mitochondrial;AKAP10;ortholog activity;kinas
2.18      ALDH1B1    NM_000692                                  oxidoreductase activity
                                 Aldehyde dehydrogenase X, mitochondrial;ALDH1B1;ortholog
-2.42     ALOXE3     NM_021628                                  3;ALOXE3;ortholog
                                 Epidermis-type lipoxygenase oxidoreductase activity
-3.72     ALS2CR2    NM_018571                                   protein beta;STRADB;ortholog
                                 STE20-related kinase adapterprotein kinase activity
2.19      AMBRA1     XM_370618   Activating molecule in BECN1-regulated autophagy protein 1;AMBRA1;ort
2.76      AMN1       NM_207337   Protein AMN1 homolog;AMN1;ortholog
-2.29     AMY2A      NM_000699                                  amylase activity
                                 Pancreatic alpha-amylase;AMY2A;ortholog
2.98      ANGPT2     NM_001147   Angiopoietin-2;ANGPT2;ortholog receptor binding;kinase regulator activity
2.34      ANGPTL2    NM_012098                                  receptor binding
                                 Angiopoietin-related protein 2;ANGPTL2;ortholog
3.13      ANKRD43    NM_175873   Ankyrin repeat domain-containing protein 43;ANKRD43;ortholog
-2.80     ANP32A     NM_006305                                  protein binding;phosphatase inhibitor activity
                                 Acidic leucine-rich nuclear phosphoprotein 32 family member A;ANP32A;o
2.07      AP3M1      NM_012095   AP-3 complex subunit mu-1;AP3M1;ortholog
2.78      APOA1      NM_000039                                  lipid transporter activity;transmembrane tran
                                 Apolipoprotein A-I(1-242);APOA1;ortholog
-3.44     APOA4      NM_000482                                  lipid transporter activity;transmembrane tran
                                 Apolipoprotein A-IV;APOA4;ortholog
2.31      APOL2      NM_030882                                  lipid
                                 Apolipoprotein L2;APOL2;ortholog transporter activity;transmembrane tran
2.13      APPL       NM_012096                                  nucleic acid binding;protein binding;small GT
                                 DCC-interacting protein 13-alpha;APPL1;ortholog
-2.20     AQP1       NM_000385   Aquaporin-1;AQP1;ortholog transmembrane transporter activity
2.22      AQP11      NM_173039   Aquaporin-11;AQP11;ortholog
2.10      AR,AREG    NM_001657   Amphiregulin;AREG;ortholog growth factor activity
2.55      ARHGEF10L NM_018125                                   cysteine-type peptidase activity
                                 Rho guanine nucleotide exchange factor 10-like protein;ARHGEF10L;ortho
-2.59     ARHGEF17 NM_014786     Rho guanine nucleotide exchange factor 17;ARHGEF17;ortholog
2.42      ARHGEF9    XM_377014                                  protein binding;small GTPase regulator activ
                                 Rho guanine nucleotide exchange factor 9;ARHGEF9;ortholog
3.24      ARID1A     NM_018450                                  nucleic protein 1A;ARID1A;ortholog
                                 AT-rich interactive domain-containing acid binding;chromatin binding
2.40      ARMCX3     NM_016607   Armadillo repeat-containing X-linked protein 3;ARMCX3;ortholog
-3.01     ARPP-21    NM_016300   cAMP-regulated phosphoprotein 21;ARPP21;ortholog
-2.22     ARR3       NM_004312   Arrestin-C;ARR3;ortholog       protein binding
3.53      ARRDC2     NM_015683   Arrestin domain-containing protein 2;ARRDC2;ortholog
-3.34   ARSA       NM_000487                                  hydrolase activity
                               Arylsulfatase A component C;ARSA;ortholog
2.31    ASB2       NM_016150   Ankyrin repeat and SOCS box protein 2;ASB2;ortholog
2.45    ASB6       NM_017873   Ankyrin repeat and SOCS box protein 6;ASB6;ortholog
2.25    ASGR2      NM_001181                                  receptor activity
                               Asialoglycoprotein receptor 2;ASGR2;ortholog
2.47    ASIP       NM_001672                                  receptor
                               Agouti-signaling protein;ASIP;ortholog binding
2.71    ATF6B      NM_004381   Processed cyclic AMP-dependent transcription factor ATF-6 beta;ATF6B;
-2.60   ATP5H      NM_006356   ATP synthase subunit d, mitochondrial;ATP5H;ortholog
2.69    ATP6AP1L   XM_043989                                  hydrolase activity;cation transmembrane
                               V-type proton ATPase subunit S1-like protein;VAS1L_HUMAN;orthologtran
2.64    ATP6V0A1   NM_005177                                  cation transmembrane transporter activity;hy
                               V-type proton ATPase 116 kDa subunit a isoform 1;ATP6V0A1;ortholog
-2.57   ATP6V0E    NM_003945                                  nucleotide phosphatase
                               V-type proton ATPase subunit e 1;ATP6V0E1;orthologactivity;nucleotide p
3.08    ATP6V1D    NM_015994                                  hydrolase activity;cation
                               V-type proton ATPase subunit D;ATP6V1D;ortholog transmembrane tran
2.46    B7H3       NM_025240   CD276 antigen;CD276;ortholog
3.43    BAIAP2L2   NM_025045                                  receptor activity
                               Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2;B
2.80    BARD1      NM_000465   BRCA1-associated RING domain protein 1;BARD1;ortholog
-2.00   BBAP       NM_138287                                  transcription factor activity;transcription facto
                               Protein deltex-3-like;DTX3L;ortholog
2.43    BBS10      NM_024685   Bardet-Biedl syndrome 10 protein;BBS10;ortholog
3.39    BFAR       NM_016561   Bifunctional apoptosis regulator;BFAR;ortholog
2.67    BHMT2      NM_017614                                  oxidoreductase activity;methyltransferase ac
                               Betaine--homocysteine S-methyltransferase 2;BHMT2;ortholog
2.19    BIN3       NM_018688   Bridging integrator 3;BIN3;ortholog
2.27    BIRC2      NM_001166                                  protein binding;peptidase inhibitor activity
                               Baculoviral IAP repeat-containing protein 2;BIRC2;ortholog
3.41    BOLA1      NM_016074   BolA-like protein 1;BOLA1;ortholog
-2.36   BPY1       NM_004679   Testis-specific basic protein Y 1;VCY1B;ortholog
-2.18   BRCA1      NM_007294                                  transcription factor activity;transcription facto
                               Breast cancer type 1 susceptibility protein;BRCA1;ortholog
-4.17   BSDC1      NM_018045   BSD domain-containing protein 1;BSDC1;ortholog
2.48    BTAF1      NM_003972                                  DNA helicase activity;nucleic
                               TATA-binding protein-associated factor 172;BTAF1;ortholog acid binding
-2.56   BTNL3      NM_006707   Butyrophilin-like protein 3;BTNL3;ortholog
-3.17   C10ORF10   NM_007021   Protein DEPP;DEPP;ortholog
2.41    C10ORF114 XM_378215    Putative uncharacterized protein C10orf114;C10orf114;ortholog
2.46    C10ORF125 NM_198472    Protein fucU homolog;C10orf125;ortholog
2.74    C10ORF53   NM_182554   Uncharacterized protein C10orf53;C10orf53;ortholog
-2.42   C11ORF34   XM_370657   Placenta-expressed transcript 1 protein;PLET1;ortholog
2.51    C11ORF36   NM_173590   Uncharacterized protein C11orf36;C11orf36;ortholog
-3.18   C11ORF61   NM_024631   Uncharacterized protein C11orf61;C11orf61;ortholog
2.47    C11ORF93   XM_071712   uncharacterized protein C11orf93
-2.82   C12ORF49   NM_024738   UPF0454 protein C12orf49;C12orf49;ortholog
-2.81   C12ORF68   XM_370691   Uncharacterized protein C12orf68;C12orf68;ortholog
2.30    C13ORF31   NM_153218   UPF0124 protein C13orf31;C13orf31;ortholog
2.31    C13ORF33   NM_032849   Uncharacterized protein C13orf33;C13orf33;ortholog
2.01    C14ORF109 XM_058628    UPF0694 transmembrane protein C14orf109;C14orf109;ortholog
2.04    C14ORF116 NM_018589                                   transcription
                               Forkhead box protein N3;FOXN3;ortholog factor activity;transcription facto
-2.77   C14ORF172 NM_152307                                   methyltransferase subunit
                               tRNA (adenine-N(1)-)-methyltransferase catalyticactivity TRM61;TRM61;o
-3.48   C14ORF2    NM_004894   6.8 kDa mitochondrial proteolipid;MP68;ortholog
2.97    C15ORF5    NM_030944   Uncharacterized protein C15orf5;C15orf5;ortholog
-2.41   C17ORF105 XM_208990    uncharacterized protein C17orf105
-3.76   C17ORF39   NM_024052   Uncharacterized protein C17orf39;C17orf39;ortholog
-2.31   C17ORF67   XM_378687   Uncharacterized protein C17orf67;C17orf67;ortholog
-2.49   C1ORF111   NM_182581   Uncharacterized protein C1orf111;C1orf111;ortholog
4.14    C1ORF156,ASTP2
                   NM_033418   UPF0558 protein C1orf156;C1orf156;ortholog
-3.03   C1ORF227   XM_086616   UPF0732 protein C1orf227
-2.97   C1ORF95    XM_375849   Uncharacterized membrane protein C1orf95;C1orf95;ortholog
-2.50   C20ORF106 XM_371401    Uncharacterized protein C20orf106;C20orf106;ortholog
-2.97   C20ORF18   NM_006462                                   zinc finger-containing activity
                               RanBP-type and C3HC4-type ubiquitin-protein ligaseprotein 1;RBCK1;ortho
-1.98   C21ORF121   NM_198078   Uncharacterized protein C21orf121;C21orf121;ortholog
-2.74   C21ORF123   NM_199175   Uncharacterized protein C21orf123;C21orf123;ortholog
2.17    C21ORF13    NM_152505   Lebercilin-like protein;LCA5L;ortholog
-2.18   C21ORF5     NM_005128   Protein dopey-2;DOPEY2;ortholog
-2.15   C22ORF18    NM_024053   Centromere protein M;CENPM;ortholog
2.50    C2ORF73     XM_059377   Uncharacterized protein C2orf73;C2orf73;ortholog
-3.14   C2ORF81     XM_371503   Uncharacterized protein C2orf81;C2orf81;ortholog
-3.69   C3ORF6      NM_174908   Coiled-coil domain-containing protein 50;CCDC50;ortholog
-2.04   C3ORF70     XM_211871   UPF0524 protein C3orf70;C3orf70;ortholog
3.06    C5ORF6      NM_016605   Protein FAM53C;FAM53C;ortholog
3.07    C6ORF152    NM_181714   Lebercilin;LCA5;ortholog
-2.43   C6ORF157    NM_198920   Ubiquitin-conjugating enzyme E2C-binding protein;UBE2CBP;ortholog
-2.41   C6ORF65     NM_152731   Coiled-coil domain-containing protein C6orf65;C6orf65;ortholog
-2.12   C6ORF85     NM_021945                                 ATPase activity, coupled
                                Solute carrier family 22 member 23;SLC22A23;orthologto transmembrane
-3.68   C7ORF19     NM_032831   Protein orai-2;ORAI2;ortholog
-2.07   C7ORF25     NM_024054   UPF0415 protein C7orf25;C7orf25;ortholog
-2.67   C7ORF3      XM_049384                                 nuclease activity;mRNA binding
                                Nucleolar MIF4G domain-containing protein 1;NOM1;ortholog
2.34    C7ORF34     NM_178829   Uncharacterized protein C7orf34;C7orf34;ortholog
2.76    C8A         NM_000562   Complement component C8 alpha chain;C8A;ortholog
-2.73   C8ORF1      NM_004337   Oxidative stress-induced growth inhibitor 2;OSGIN2;ortholog
2.06    C8ORF41     NM_025115   Uncharacterized protein C8orf41;C8orf41;ortholog
2.56    C9ORF115    XM_059972                                 hydrolase activity, acting on ester bonds
                                Probable peptidyl-tRNA hydrolase;PTRH1;ortholog
2.14    C9ORF125    NM_032342   Transmembrane protein C9orf125;C9orf125;ortholog
2.36    C9ORF4      XM_378078   Uncharacterized protein C9orf4;C9orf4;ortholog
3.06    C9ORF81     XM_095991   Centrosomal protein of 78 kDa;CEP78;ortholog
-2.02   CA8         NM_004056   Carbonic anhydrase-related protein;CA8;ortholog
-1.95   CACNB1      NM_000723                                 voltage-gated calcium channel activity;voltag
                                Voltage-dependent L-type calcium channel subunit beta-1;CACNB1;orthol
2.02    CAPN2       NM_001748                                 cysteine-type
                                Calpain-2 catalytic subunit;CAPN2;ortholog peptidase activity;calcium ion
1.99    CARD14      NM_024110   Caspase recruitment domain-containing protein 14;CARD14;ortholog
2.26    CART        NM_004291   CART(42-89);CARTPT;ortholog
2.66    CASC1       NM_018272   Cancer susceptibility candidate protein 1;CASC1;ortholog
2.98    CBLN1       NM_004352                                 neuropeptide hormone activity
                                [des-Ser1]-cerebellin;CBLN1;ortholog
-2.92   CBX4        NM_003655                                 transcription factor
                                E3 SUMO-protein ligase CBX4;CBX4;ortholog activity;chromatin binding
-2.86   CCDC134     NM_024821   Coiled-coil domain-containing protein 134;CCDC134;ortholog
-2.33   CCDC42      NM_144681   Coiled-coil domain-containing protein 42A;CCDC42;ortholog
2.43    CCDC53      NM_016053   Coiled-coil domain-containing protein 53;CCDC53;ortholog
2.89    CCDC57      NM_198082   Coiled-coil domain-containing protein 57;CCDC57;ortholog
3.00    CCDC6       NM_005436   Coiled-coil domain-containing protein 6;CCDC6;ortholog
2.57    CCDC70      NM_031290   Coiled-coil domain-containing protein 70;CCDC70;ortholog
-2.47   CCDC92      NM_025140   Coiled-coil domain-containing protein 92;CCDC92;ortholog
-4.05   CCL4        NM_002984   MIP-1-beta(3-69);CCL4;orthologchemokine activity
2.14    CCNG2       NM_004354   Cyclin-G2;CCNG2;ortholog protein binding;kinase activator activity;kinas
3.22    CCNT1       NM_001240   Cyclin-T1;CCNT1;ortholog      transcription factor activity;protein binding;ki
2.57    CD209       NM_021155   CD209 antigen;CD209;ortholog  receptor activity
2.75    CD47        NM_001777                                 receptor activity;protein binding;small GTPas
                                Leukocyte surface antigen CD47;CD47;ortholog
2.56    CD81        NM_004356   CD81 antigen;CD81;ortholog receptor binding
2.51    CD83        NM_004233   CD83 antigen;CD83;ortholog
3.13    CDC25C      NM_001790                                 phosphoprotein phosphatase activity;phosph
                                M-phase inducer phosphatase 3;CDC25C;ortholog
2.47    CDH17       NM_004063   Cadherin-17;CDH17;ortholog calcium ion binding
-2.09   CDH19       NM_021153   Cadherin-19;CDH19;ortholog calcium ion binding
2.19    CDH28       NM_152750                                 calcium ion
                                Cadherin-like protein 28;CDH28;ortholog binding
-2.73   CDH29       XM_371639                                 calcium ion
                                Cadherin-like protein 29;CDH29;ortholog binding
2.39    CDK5RAP1 NM_016082     CDK5 regulatory subunit-associated protein 1;CDK5RAP1;ortholog
2.07    CENTG3     NM_031946                                  nucleic acid binding;protein protein 3;AGAP
                               Arf-GAP, GTPase, ANK repeat and PH domain-containingbinding;small GT
-2.56   CETN2      NM_004344   Centrin-2;CETN2;ortholog       calcium ion binding;calmodulin binding
-2.28   CGRRF1     NM_006568   Cell growth regulator with RING finger domain protein 1;CGRRF1;ortholog
-3.29   CH25H      NM_003956                                  oxidoreductase
                               Cholesterol 25-hydroxylase;CH25H;ortholog activity
2.84    CHFR       NM_018223                                  ubiquitin-protein ligase activity
                               E3 ubiquitin-protein ligase CHFR;CHFR;ortholog
2.10    CHIC2      NM_012110   Cysteine-rich hydrophobic domain 2 protein;CHIC2;ortholog
-3.12   CHN1       NM_001822   N-chimaerin;CHN1;ortholog protein binding;small GTPase regulator activ
-2.53   CHN2       NM_004067   Beta-chimaerin;CHN2;ortholog   protein binding;small GTPase regulator activ
-2.34   CHRAC1     NM_017444                                  DNA-directed DNA polymerase
                               Chromatin accessibility complex protein 1;CHRAC1;ortholog activity;trans
3.41    CHRNB4     NM_000750                                  acetylcholine receptor activity;cation
                               Neuronal acetylcholine receptor subunit beta-4;CHRNB4;ortholog transm
-2.54   CHST13     NM_152889                                   13;CHST13;ortholog
                               Carbohydrate sulfotransferasetransferase activity
2.73    CIG5       NM_080657   Radical S-adenosyl methionine domain-containing protein 2;RSAD2;orthol
2.09    CKAP2L     NM_152515                                  structural constituent of cytoskeleton
                               Cytoskeleton-associated protein 2-like;CKAP2L;ortholog
3.13    CKM        NM_001824                                  amino acid kinase activity
                               Creatine kinase M-type;CKM;ortholog
3.31    CLCN5      NM_000084                                  anion channel
                               Chloride channel protein 5;CLCN5;ortholog activity
2.30    CLDN3      NM_001306   Claudin-3;CLDN3;ortholog
2.35    CLDN5      NM_003277   Claudin-5;CLDN5;ortholog
2.70    CLIC3      NM_004669                                  transferase activity;anion
                               Chloride intracellular channel protein 3;CLIC3;ortholog channel activity
3.11    CLN3       NM_000086   Battenin;CLN3;ortholog
-2.09   CLPX       NM_006660   ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial;
2.02    CMTM1      NM_052999   CKLF-like MARVEL transmembrane domain-containing protein 1;CMTM1;
2.24    CNGA1      NM_000087                                  receptor activity;voltage-gated potassium ch
                               cGMP-gated cation channel alpha-1;CNGA1;ortholog
1.95    CNGB3      NM_019098                                  receptor beta-3;CNGB3;ortholog
                               Cyclic nucleotide-gated cation channelactivity;voltage-gated potassium ch
2.33    CNNM2      NM_017649   Metal transporter CNNM2;CNNM2;ortholog
2.92    CNOT2      NM_014515                                  transcription factor activity;transcription facto
                               CCR4-NOT transcription complex subunit 2;CNOT2;ortholog
2.66    CNOT4      NM_013316                                  transcription factor activity;transcription facto
                               CCR4-NOT transcription complex subunit 4;CNOT4;ortholog
2.13    COL15A1    NM_001855   Endostatin;COL15A1;orthologextracellular matrix structural constituent
2.06    COL18A1    NM_030582   Endostatin;COL18A1;orthologextracellular matrix structural constituent
-3.09   COL28A1    XM_295195   Collagen alpha-1(XXVIII) chain;COL28A1;ortholog
3.44    COL4A1     NM_001845   Collagen alpha-1(IV) chain;COL4A1;ortholog
2.90    COL4A2     NM_001846   Canstatin;COL4A2;ortholog extracellular matrix structural constituent
2.18    COL4A6     NM_001847                                  extracellular matrix structural constituent
                               Collagen alpha-6(IV) chain;COL4A6;ortholog
2.24    COMMD10    NM_016144   COMM domain-containing protein 10;COMMD10;ortholog
2.66    CORO1B     NM_020441   Coronin-1B;CORO1B;orthologstructural constituent of cytoskeleton;actin b
2.69    CPA1       NM_001868                                  metallopeptidase activity
                               Carboxypeptidase A1;CPA1;ortholog
2.99    CPN1       NM_001308                                   chain;CPN1;ortholog
                               Carboxypeptidase N catalytic metallopeptidase activity
-2.86   CREG       NM_003851   Protein CREG1;CREG1;ortholog
2.04    CRELD1     NM_015513   Cysteine-rich with EGF-like domain protein 1;CRELD1;ortholog
2.47    CRIM1      NM_016441   Processed cysteine-rich motor neuron 1 protein;CRIM1;ortholog
-4.19   CRIP1      NM_001311                                  structural
                               Cysteine-rich protein 1;CRIP1;ortholog constituent of cytoskeleton
2.47    CRK        NM_005206   Proto-oncogene C-crk;CRK;ortholog
2.01    CXCL17     NM_198477   VEGF co-regulated chemokine 1;CXCL17;ortholog
2.04    CXORF20    NM_153346   Uncharacterized protein CXorf20;CXorf20;ortholog
2.58    CXORF41    NM_173494   Uncharacterized protein CXorf41;CXorf41;ortholog
-2.03   CXORF66    XM_298053   uncharacterized protein CXorf662
3.08    CYB5       NM_001914   Cytochrome b5;CYB5A;ortholog   oxidoreductase activity
3.02    CYLD       NM_015247                                  structural constituent of ribosome;nucleic ac
                               Probable ubiquitin carboxyl-terminal hydrolase CYLD;CYLD;ortholog
-3.51   CYP2D6     NM_000106                                  oxidoreductase activity
                               Cytochrome P450 2D6;CYP2D6;ortholog
-2.66   D17S1718,SCYA3L1
                   NM_021006   LD78-beta(5-70);CCL3L3;orthologchemokine activity
-2.11   DBI        NM_020548                                  protein binding;enzyme inhibitor activity
                               Acyl-CoA-binding protein;DBI;ortholog
-1.97   DCST2      NM_144622   DC-STAMP domain-containing protein 2;DCST2;ortholog
3.53    DDC        NM_000790                                    carboxy-lyase activity
                               Aromatic-L-amino-acid decarboxylase;DDC;ortholog
-2.45   DDX51      NM_175066                                     DDX51;DDX51;ortholog
                               ATP-dependent RNA helicaseRNA helicase activity;nucleic acid binding
-2.59   DDX55      NM_020936                                     DDX55;DDX55;ortholog
                               ATP-dependent RNA helicaseRNA helicase activity;nucleic acid binding
2.91    DERP6      NM_015362   Dermal papilla-derived protein 6;DERP6;ortholog
2.27    DHDH       NM_014475                                    oxidoreductase activity
                               Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;DHDH;ortholog
2.68    DIRC2      NM_032839                                    transmembrane transporter activity
                               Disrupted in renal carcinoma protein 2;DIRC2;ortholog
2.28    DISC1      NM_018662   Disrupted in schizophrenia 1 protein;DISC1;ortholog
-2.83   DIXDC1     XM_290496   Dixin;DIXDC1;ortholog            receptor binding;enzyme regulator activity
-2.33   DLG4       NM_001365   Disks large homolog 4;DLG4;ortholog
2.05    DLGAP1     NM_004746   Disks large-associated protein 1;DLGAP1;ortholog
-2.73   DLGAP3     XM_035601   Disks large-associated protein 3;DLGAP3;ortholog
3.68    DMGDH      NM_013391                                    oxidoreductase activity
                               Dimethylglycine dehydrogenase, mitochondrial;DMGDH;ortholog
3.21    DNAJD1     NM_013238   DnaJ homolog subfamily C member 15;DNAJC15;ortholog
-2.80   DND1       NM_194249                                    RNA binding
                               Dead end protein homolog 1;DND1;ortholog
-2.03   DOCK8      NM_203447                                    protein binding;small
                               Dedicator of cytokinesis protein 8;DOCK8;ortholog GTPase regulator activ
2.05    DPEP2      NM_022355   Dipeptidase 2;DPEP2;ortholog     metallopeptidase activity
-2.39   DPP9       NM_139159                                    serine-type peptidase activity
                               Dipeptidyl peptidase 9;DPP9;ortholog
2.91    DPYS       NM_001385   Dihydropyrimidinase;DPYS;orthologhydrolase activity
-3.01   DRAM2      NM_178454   Transmembrane protein 77;TMEM77;ortholog
2.58    DSPP       NM_014208   Dentin sialoprotein;DSPP;ortholog
-2.17   DUSP26     NM_024025                                    phosphoprotein phosphatase
                               Dual specificity protein phosphatase 26;DUSP26;ortholog activity;phosph
2.14    DUSP3      NM_004090                                    phosphoprotein phosphatase activity;phosph
                               Dual specificity protein phosphatase 3;DUSP3;ortholog
-2.60   DUX4       NM_033178                                    transcription
                               Double homeobox protein 4;DUX4;ortholog factor activity;transcription facto
-2.53   DXS9928E   NM_004699   Protein FAM50A;FAM50A;ortholog
2.24    DZIP1L     NM_173543                                    nucleic acid
                               Zinc finger protein DZIP1L;DZIP1L;orthologbinding
3.00    E2F4       NM_001950                                    transcription
                               Transcription factor E2F4;E2F4;ortholog factor activity;transcription facto
2.52    ECHDC1     NM_018479                                    oxidoreductase activity;acetyltransferase
                               Enoyl-CoA hydratase domain-containing protein 1;ECHDC1;ortholog ac
-2.77   EDEM2      NM_018217                                    hydrolase activity
                               ER degradation-enhancing alpha-mannosidase-like 2;EDEM2;ortholog
-2.91   EEF1A2     NM_001958                                    translation factor
                               Elongation factor 1-alpha 2;EEF1A2;ortholog activity, nucleic acid bindin
2.42    EEF2       NM_001961   Elongation factor 2;EEF2;orthologtranslation factor activity, nucleic acid bindin
2.60    EFNA5      NM_001962   Ephrin-A5;EFNA5;ortholog receptor binding
3.64    EFNB1      NM_004429   Ephrin-B1;EFNB1;ortholog receptor binding
2.83    EGFLAM     NM_152403   Pikachurin;EGFLAM;ortholog
-2.10   EGR1       NM_001964                                     1;EGR1;ortholog
                               Early growth response proteintranscription factor activity;transcription facto
3.20    EHBP1L1    XM_170658                                    structural 1;EHBP1L1;ortholog
                               EH domain-binding protein 1-like proteinconstituent of cytoskeleton;actin b
2.52    EIF2B1     NM_001414                                    isomerase activity;translation initiation factor
                               Translation initiation factor eIF-2B subunit alpha;EIF2B1;ortholog
3.99    EIF2C1     NM_012199                                    translation 1;EIF2C1;ortholog
                               Eukaryotic translation initiation factor 2Cfactor activity, nucleic acid bindin
2.47    EIF3S2     NM_003757                                    translation factor I;EIF3I;ortholog
                               Eukaryotic translation initiation factor 3 subunitactivity, nucleic acid bindin
-2.45   ELAVL2     NM_004432                                    RNA binding
                               ELAV-like protein 2;ELAVL2;ortholog
2.02    ELF4       NM_001421                                    transcription factor activity;receptor binding;t
                               ETS-related transcription factor Elf-4;ELF4;ortholog
2.25    ELP3       NM_018091                                    acetyltransferase activity
                               Elongator complex protein 3;ELP3;ortholog
2.67    ENTPD8     NM_138793                                    nucleotide phosphatase activity;nucleotide p
                               Ectonucleoside triphosphate diphosphohydrolase 8;ENTPD8;ortholog
2.20    EPHB1      NM_004441                                    transmembrane receptor protein kinase activ
                               Ephrin type-B receptor 1;EPHB1;ortholog
2.02    EPHB2      NM_004442                                    transmembrane receptor protein kinase activ
                               Ephrin type-B receptor 2;EPHB2;ortholog
2.50    EPHB2      NM_004442                                    transmembrane receptor protein kinase activ
                               Ephrin type-B receptor 2;EPHB2;ortholog
2.34    ERC1       NM_015064                                    protein member 1;ERC1;ortholog
                               ELKS/RAB6-interacting/CAST family binding;small GTPase regulator activ
2.04    ERN1       NM_001433   Endoribonuclease;ERN1;ortholog   protein kinase activity
1.99    ERO1L      NM_014584                                    oxidoreductase activity
                               ERO1-like protein alpha;ERO1L;ortholog
2.38    ETFA       NM_000126   Electron transfer flavoprotein subunit alpha, mitochondrial;ETFA;ortholog
3.20    ETV7       NM_016135                                    transcription
                               Transcription factor ETV7;ETV7;ortholog factor activity;receptor binding;t
2.77    EXTL2      NM_001439                                    transferase activity, transferring glycosyl gro
                               Processed exostosin-like 2;EXTL2;ortholog
2.16    F2         NM_000506   Thrombin heavy chain;F2;ortholog serine-type peptidase activity
-3.07   FAM11A     NM_032508   Transmembrane protein 185A;TMEM185A;ortholog
2.68    FAM133B    NM_152789   Protein FAM133B;FAM133B;ortholog
-2.73   FAM173A    NM_023933   Protein FAM173A;FAM173A;ortholog
2.43    FAM18B     NM_016078   Protein FAM18B;FAM18B;ortholog
2.65    FAM43A     NM_153690   Protein FAM43A;FAM43A;ortholog
-2.04   FAM57A     NM_024792   Protein FAM57A;FAM57A;ortholog
2.16    FANCD2     NM_033084   Fanconi anemia group D2 protein;FANCD2;ortholog
-2.57   FARSLA     NM_004461                                  aminoacyl-tRNA ligase activity
                               Phenylalanyl-tRNA synthetase alpha chain;FARSA;ortholog
-2.31   FASTKD1    NM_024622   FAST kinase domain-containing protein 1;FASTKD1;ortholog
-3.52   FASTKD5    NM_021826   FAST kinase domain-containing protein 5;FASTKD5;ortholog
-2.09   FBF1       XM_371079   Fas-binding factor 1;FBF1;ortholog
2.29    FBN2       NM_001999   Fibrillin-2;FBN2;ortholog      extracellular matrix structural constituent;ca
-2.43   FBXL3A     NM_012158   F-box/LRR-repeat protein 3;FBXL3;ortholog
-2.03   FBXL3P     NM_012159   F-box/LRR-repeat protein 21;FBXL21;ortholog
2.56    FBXL5      NM_012161   F-box/LRR-repeat protein 5;FBXL5;ortholog
2.77    FBXW9      NM_032301   F-box/WD repeat-containing protein 9;FBXW9;ortholog
2.07    FCMD       NM_006731   Fukutin;FKTN;ortholog
2.71    FCRLA      NM_032738                                  receptor activity
                               Fc receptor-like A;FCRLA;ortholog
-3.16   FEZF1      XM_371948                                  transcription factor
                               Fez family zinc finger protein 1;FEZF1;ortholog activity;transcription facto
-2.28   FGF23      NM_020638                                  growth factor activity
                               Fibroblast growth factor 23 C-terminal peptide;FGF23;ortholog
2.32    FGF4       NM_002007                                  growth factor
                               Fibroblast growth factor 4;FGF4;ortholog activity
-2.59   FGFR1OP    NM_007045   FGFR1 oncogene partner;FGFR1OP;ortholog
2.27    FGFRL1     NM_021923                                  transmembrane receptor protein kinase activ
                               Fibroblast growth factor receptor-like 1;FGFRL1;ortholog
3.08    FKHL18     NM_004118                                  transcription
                               Forkhead box protein S1;FOXS1;ortholog factor activity;transcription facto
-2.35   FLJ13197   NM_024614   NM_024614.1 was permanently suppressed because currently there is su
2.26    FLJ14959   XM_371139   This record was removed as a result of standard genome annotation proce
-2.65   FLJ22659   XM_378723   This record was removed as a result of standard genome annotation proce
-2.48   FLJ30435   XM_376845   NM_174950.2 was permanently suppressed because it is now thought tha
-5.42   FLJ35785   NM_173613   This record was removed by RefSeq staff.
-2.38   FLJ45651   NM_198442   This record was removed by RefSeq staff.
-3.24   FLJ45684   NM_207462   NM_207462.1 was permanently suppressed because it is a nonsense-me
2.57    FLNB       NM_001457   Filamin-B;FLNB;ortholog        structural constituent of cytoskeleton;actin b
2.36    FLRT2      NM_013231                                  receptor activity
                               Leucine-rich repeat transmembrane protein FLRT2;FLRT2;ortholog
2.21    FMO5       NM_001461                                  oxidoreductase activity
                               Dimethylaniline monooxygenase [N-oxide-forming] 5;FMO5;ortholog
-2.36   FNDC5      NM_153756   Fibronectin type III domain-containing protein 5;FNDC5;ortholog
2.15    FOXD4L2    NM_199135                                  transcription factor activity;transcription facto
                               Forkhead box protein D4-like 2;FOXD4L2;ortholog
-2.86   FOXI2      NM_207426                                  transcription factor activity;transcription facto
                               Forkhead box protein I2;FOXI2;ortholog
2.33    FOXK2      NM_004514                                  transcription
                               Forkhead box protein K2;FOXK2;ortholog factor activity;transcription facto
2.34    FOXN4      NM_213596                                  transcription
                               Forkhead box protein N4;FOXN4;ortholog factor activity;transcription facto
3.51    FRMD8      NM_031904   FERM domain-containing protein 8;FRMD8;ortholog
2.27    FSIP2      NM_173651   Fibrous sheath-interacting protein 2;FSIP2;ortholog
2.40    FST        NM_013409   Follistatin;FST;ortholog       protein binding
-2.57   FTCD       NM_006657                                  transferase activity;hydrolase
                               Formimidoyltetrahydrofolate cyclodeaminase;FTCD;orthologactivity;deamin
-2.83   FTHFD      NM_012190                                  oxidoreductase activity
                               10-formyltetrahydrofolate dehydrogenase;ALDH1L1;ortholog
-2.17   FUT5       NM_002034                                  transferase activity, transferring glycosyl gro
                               Alpha-(1,3)-fucosyltransferase;FUT5;ortholog
4.07    FXYD2      NM_001680                                  cation transmembrane transporter activity
                               Sodium/potassium-transporting ATPase gamma chain;FXYD2;ortholog
2.12    FZR1       NM_016263                                  protein binding
                               Fizzy-related protein homolog;FZR1;ortholog
-2.35   GABARAP    NM_007278                                  structural constituent of cytoskeleton;microt
                               Gamma-aminobutyric acid receptor-associated protein;GABARAP;ortholo
2.20    GABPA      NM_002040                                  transcription factor
                               GA-binding protein alpha chain;GABPA;ortholog activity;transcription facto
2.13    GABRG1     NM_173536                                  GABA receptor activity;ligand-gated ion chan
                               Gamma-aminobutyric acid receptor subunit gamma-1;GABRG1;ortholog
-2.49   GAGE1      NM_001468   G antigen 1;GAGE1;ortholog
-2.08   GAGE2      NM_001472   G antigen 2A/2B;GAGE2B;ortholog
3.15    GALGT2      NM_153446 Beta-1,4 N-acetylgalactosaminyltransferase 2;B4GALNT2;ortholog
2.38    GALM        NM_138801 Aldose 1-epimerase;GALM;ortholog racemase and epimerase activity
3.93    GAPDH       NM_002046                                  oxidoreductase activity
                               Glyceraldehyde-3-phosphate dehydrogenase;GAPDH;ortholog
-2.32   GAS1        NM_002048 Growth arrest-specific protein 1;GAS1;ortholog
-2.40   GATA5                                                  nuclease activity;transcription factor activity;
                    NM_080473 Transcription factor GATA-5;GATA5;ortholog
2.18    GDF8        NM_005259                                  growth factor activity
                               Growth/differentiation factor 8;MSTN;ortholog
2.48    GDF9                                                   growth factor activity
                    NM_005260 Growth/differentiation factor 9;GDF9;ortholog
2.09    GDNF                                                   neurotrophin receptor binding;growth factor a
                    NM_000514 Glial cell line-derived neurotrophic factor;GDNF;ortholog
2.57    GJB6        NM_006783                                  gap junction
                               Gap junction beta-6 protein;GJB6;ortholog channel activity
2.29    GNA11                                                  GTPase activity;protein binding
                    NM_002067 Guanine nucleotide-binding protein subunit alpha-11;GNA11;ortholog
-2.07   GNB2                                                   GTPase activity;protein binding
                    NM_005273 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;GNB2;or
-2.55   GNMT        NM_018960 Glycine N-methyltransferase;GNMT;ortholog
2.34    GNPDA2                                                 hydrolase activity;isomerase
                    NM_138335 Glucosamine-6-phosphate isomerase 2;GNPDA2;ortholog activity
-4.18   GPR114                                                 G-protein coupled receptor activity
                    NM_153837 Probable G-protein coupled receptor 114;GPR114;ortholog
2.12    GPR137      NM_020155 Integral membrane protein GPR137;GPR137;ortholog
2.33    GPR137C     XM_290615 Integral membrane protein GPR137C;GPR137C;ortholog
2.53    GPR89B      NM_016334 Protein GPR89;GPR89B;ortholog
2.85    GPX6                                                   oxidoreductase activity;peroxidase activity
                    NM_182701 Glutathione peroxidase 6;GPX6;ortholog
-3.29   GRB10                  Growth factor receptor-bound protein 10;GRB10;ortholog
                    NM_001001549
3.61    GSG1        NM_031289 Germ cell-specific gene 1 protein;GSG1;ortholog
-2.91   GTF2A1                                                 transcription factor activity;transcription facto
                    NM_015859 Transcription initiation factor IIA beta chain;GTF2A1;ortholog
2.19    GTF2IRD1                                               transcription factor activity;transcription facto
                    NM_005685 General transcription factor II-I repeat domain-containing protein 1;GTF2IR
-2.09   GYG2        NM_003918 Glycogenin-2;GYG2;ortholog transferase activity, transferring glycosyl gro
-3.62   H2BFA       NM_003518 Histone H2B type 1-C/E/F/G/I;HIST1H2BI;ortholog
2.04    HCLS1                                                  structural constituent of cytoskeleton;transc
                    NM_005335 Hematopoietic lineage cell-specific protein;HCLS1;ortholog
2.73    HEATR7B2    NM_173489 HEAT repeat-containing protein 7B2;HEATR7B2;ortholog
-2.54   HECTD3                                                 ubiquitin-protein ligase activity
                    NM_024602 Probable E3 ubiquitin-protein ligase HECTD3;HECTD3;ortholog
-3.05   HELIC1                                                 DNA helicase activity;RNA helicase activity;
                    NM_006828 Activating signal cointegrator 1 complex subunit 3;ASCC3;ortholog
-2.84   HEPH        NM_014799 Hephaestin;HEPH;ortholog oxidoreductase activity;serine-type peptidas
2.84    HERC3                                                  ubiquitin-protein ligase activity
                    NM_014606 Probable E3 ubiquitin-protein ligase HERC3;HERC3;ortholog
-2.11   HHLA3       NM_007071 HERV-H LTR-associating protein 3;HHLA3;ortholog
-2.08   HINT1                                                  nucleotide 1;HINT1;ortholog
                    NM_005340 Histidine triad nucleotide-binding protein phosphatase activity;nucleotide p
2.55    HINT3                                                  damaged 3;HINT3;ortholog
                    NM_138571 Histidine triad nucleotide-binding proteinDNA binding
2.35    HIST1H2BA   NM_170610 Histone H2B type 1-A;HIST1H2BA;ortholog
-3.41   HIST1H3B    NM_003537 Histone H3.1;HIST1H3J;ortholog
2.11    HLA-B       NM_005514 HLA class I histocompatibility antigen, B-8 alpha chain;HLA-B;ortholog
3.15    HLA-DRB1    NM_002124 HLA class II histocompatibility antigen, DRB1-1 beta chain;HLA-DRB1;ort
3.03    HMG4L       NM_178467 High mobility group protein B3-like;HMG4L;ortholog
-2.65   HMGB3       NM_005342 High mobility group protein B3;HMGB3;ortholog
-3.28   HOXA6                                                  transcription
                    NM_024014 Homeobox protein Hox-A6;HOXA6;orthologfactor activity;transcription facto
2.42    IDE                                                    metallopeptidase activity
                    NM_004969 Insulin-degrading enzyme;IDE;ortholog
-2.79   IER5L       XM_372145 Immediate early response gene 5-like protein;IER5L;ortholog
2.92    IFI44       NM_006417 Interferon-induced protein 44;IFI44;ortholog
-2.21   IFNA13                                                 hematopoietin/interferon-class (D200-domain
                    NM_006900 Interferon alpha-1/13;IFNA13;ortholog
2.50    IGFBP3      NM_000598 Insulin-like growth factor-binding protein 3;IGFBP3;ortholog
-2.36   IHPK1                                                  kinase activity
                    NM_153273 Inositol hexaphosphate kinase 1;IHPK1;ortholog
2.61    IL1B        NM_000576                                  h
                               Interleukin-1 beta;IL1B;orthologematopoietin/interferon-class (D200-domain
-2.60   IL1R2                                                  cytokine receptor activity
                    NM_004633 Interleukin-1 receptor type II;IL1R2;ortholog
-2.25   IL1RL2                                                 cytokine receptor activity
                    NM_003854 Interleukin-1 receptor-like 2;IL1RL2;ortholog
2.70    IL22RA2     NM_052962                                  cytokine receptor activity
                               Interleukin-22 receptor subunit alpha-2;IL22RA2;ortholog
2.51    IL28B       NM_172139 Interleukin-28B;IL28B;ortholog
2.78    IL4R                                                    alpha chain;IL4R;ortholog
                    NM_000418 Soluble interleukin-4 receptor cytokine receptor activity
2.73    ILT7                                                   receptor activity
                    NM_012276 Leukocyte immunoglobulin-like receptor subfamily A member 4;LILRA4;or
2.05    IMPDH2      NM_000884                                  oxidoreductase activity
                                Inosine-5'-monophosphate dehydrogenase 2;IMPDH2;ortholog
-2.31   INMT        NM_006774                                  methyltransferase activity
                                Indolethylamine N-methyltransferase;INMT;ortholog
2.03    INVS        NM_014425 Inversin;INVS;ortholog
2.61    IREM2                                                  receptor activity
                    NM_181449 CMRF35-like molecule 2;CD300E;ortholog
2.23    IRS2        NM_003749   Insulin receptor substrate 2;IRS2;ortholog
2.86    JAGN1       NM_032492 Protein jagunal homolog 1;JAGN1;ortholog
-2.46   JMJD4                                                  receptor activity
                    NM_023007 JmjC domain-containing protein 4;JMJD4;ortholog
-3.23   KCNJ12                                                 voltage-gated potassium channel activity;volt
                    NM_021012 ATP-sensitive inward rectifier potassium channel 12;KCNJ12;ortholog
-2.15   KCNK16                                                  K member 16;KCNK16;ortholog
                    NM_032115 Potassium channel subfamily voltage-gated potassium channel activity;volt
-2.16   KCTD17                                                 voltage-gated potassium channel
                    NM_024681 BTB/POZ domain-containing protein KCTD17;KCTD17;ortholog activity;volt
2.24    KCTD2                                                  voltage-gated potassium channel
                    NM_015353 BTB/POZ domain-containing protein KCTD2;KCTD2;ortholog activity;volt
2.02    KIAA0433    NM_015216   Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinas
-3.25   KIAA0649    NM_014811 Protein KIAA0649;KIAA0649;ortholog
-2.28   KIAA1009    XM_376518 Protein QN1 homolog;KIAA1009;ortholog
2.20    KIAA1033    NM_015275 UPF0681 protein KIAA1033;KIAA1033;ortholog
2.21    KIAA1049    NM_014972 Transcription factor 25;TCF25;ortholog
2.49    KIAA1191    NM_020444 UPF0498 protein KIAA1191;KIAA1191;ortholog
2.20    KIAA1229                                               extracellular matrix
                    XM_030665 Outer dense fiber protein 2-like;ODF2L;ortholog structural constituent
2.47    KIAA1285    NM_015694                                  transcription
                                Zinc finger protein 777;ZNF777;ortholog factor activity;transcription facto
2.24    KIAA1340    XM_044836 Kelch domain-containing protein 5;KLHDC5;ortholog
2.66    KIAA1363                                               lipase activity
                    NM_020792 Arylacetamide deacetylase-like 1;AADACL1;ortholog
-2.18   KIAA1443    NM_020834                                   protein Homez;HOMEZ;ortholog
                                Homeobox and leucine zippertranscription factor activity;transcription facto
-2.39   KIAA1522    XM_036299 Uncharacterized protein KIAA1522;KIAA1522;ortholog
-2.32   KIAA1587    NM_020932 Melanoma-associated antigen E1;MAGEE1;ortholog
-2.27   KIAA1596    XM_048128 Fanconi anemia group M protein;FANCM;ortholog
-2.49   KIAA1698    NM_030628 Integrator complex subunit 5;INTS5;ortholog
2.90    KIF1B                                                  microtubule
                    NM_015074 Kinesin-like protein KIF1B;KIF1B;ortholog motor activity;structural constitu
-2.23   KIFC1                                                  microtubule
                                Kinesin-like protein KIFC1;KIFC1;ortholog motor activity;structural constitu
                    XM_371813, NM_002263
-3.06   KL          NM_153683 Klotho peptide;KL;ortholog glucosidase activity;hydrolase activity, hydro
2.37    KLHDC6                                                 structural constituent of
                    NM_207335 Kelch domain-containing protein 6;KLHDC6;ortholog cytoskeleton;actin b
2.58    KLHL14      XM_035405 Kelch-like protein 14;KLHL14;ortholog
-2.47   KRT12                                                  structural constituent of cytoskeleton
                    NM_000223 Keratin, type I cytoskeletal 12;KRT12;ortholog
-2.02   KRT5                                                   structural constituent of cytoskeleton
                    NM_000424 Keratin, type II cytoskeletal 5;KRT5;ortholog
-2.92   LACRT       NM_033277 Extracellular glycoprotein lacritin;LACRT;ortholog
2.62    LANCL2      NM_018697 LanC-like protein 2;LANCL2;ortholog
2.00    LARP4       NM_052879 La-related protein 4;LARP4;ortholog
2.64    LARS2                                                  aminoacyl-tRNA ligase activity
                    NM_015340 Probable leucyl-tRNA synthetase, mitochondrial;LARS2;ortholog
-2.39   LCK                                                    non-membrane spanning protein tyrosine kin
                    NM_005356 Proto-oncogene tyrosine-protein kinase LCK;LCK;ortholog
-2.17   LCN15                                                  isomerase activity
                    NM_203347 Uncharacterized lipocalin UNQ2541/PRO6093;YA002_HUMAN;ortholog
-2.23   LEF1                                                   nucleic acid binding
                    NM_016269 Lymphoid enhancer-binding factor 1;LEF1;ortholog
2.66    LILRB5                                                 receptor activity
                    NM_006840 Leukocyte immunoglobulin-like receptor subfamily B member 5;LILRB5;or
-1.99   LIMD2       NM_030576                                    2;LIMD2;ortholog
                                LIM domain-containing proteinstructural constituent of cytoskeleton
2.69    LIN7C       NM_018362 Lin-7 homolog C;LIN7C;ortholog
2.46    LINC00174   NM_181722 NM_181722.2: This RefSeq was permanently suppressed because curren
2.61    LINC00346   NM_178514 NM_178514.3 was permanently suppressed because currently there is su
-2.02   LMO4                                                   transcription factor activity;transcription facto
                    NM_006769 LIM domain transcription factor LMO4;LMO4;ortholog
2.05    LMOD1       NM_012134 Leiomodin-1;LMOD1;ortholog structural constituent of cytoskeleton;actin b
-2.89   LOC132870   XM_059608 This record was removed as a result of standard genome annotation proce
-2.13   LOC136143   XM_069734 This record was removed as a result of standard genome annotation proce
1.97    LOC144766   XM_378419 This record was removed as a result of standard genome annotation proce
-2.40   LOC147942   XM_085967 This record was removed as a result of standard genome annotation proce
2.63    LOC149934   XM_086725   NM_001039379.1 was permanently suppressed because it is now thought
-2.70   LOC163301   XM_088797   This record was removed as a result of standard genome annotation proce
-2.35   LOC196415   XM_378346   This record was removed as a result of standard genome annotation proce
-2.63   LOC200493   XM_115715   This record was removed as a result of standard genome annotation proce
-3.41   LOC254439   XM_170659   This record was removed as a result of standard genome annotation proce
2.41    LOC255189   XM_172929   This record was removed as a result of standard genome annotation proce
-2.42   LOC256374   XM_170597   This record was removed as a result of standard genome annotation proce
-2.31   LOC283065   XM_210876   This record was removed as a result of standard genome annotation proce
2.39    LOC283214   XM_378303   This record was removed as a result of standard genome annotation proce
2.69    LOC283332   XM_378355   This record was removed as a result of standard genome annotation proce
2.64    LOC283480   XM_378430   This record was removed as a result of standard genome annotation proce
2.21    LOC283483   XM_378431   This record was removed as a result of standard genome annotation proce
2.63    LOC284009   XM_378642   NM_001025459.2: This RefSeq was permanently suppressed because it is
-3.04   LOC284385   XM_378777   This record was removed as a result of standard genome annotation proce
-2.60   LOC284912   XM_209413   NM_203375.1 was permanently suppressed because currently there is ins
-2.64   LOC285000   XM_379119   This record was removed as a result of standard genome annotation proce
3.38    LOC285189   XM_376111   This record was removed as a result of standard genome annotation proce
-3.03   LOC285647   XM_209700   This record was removed as a result of standard genome annotation proce
2.04    LOC285735   XM_379433   NM_001037231.1 was permanently suppressed because currently there is
2.00    LOC286094   XM_212170   This record was removed as a result of standard genome annotation proce
2.30    LOC286161   NM_181648   This record was removed by RefSeq staff; the sequence does not appear t
-2.05   LOC286453   XM_210054   This record was removed by RefSeq staff.
1.99    LOC286480   NM_207353   This record was removed by RefSeq staff; the sequence does not appear t
-2.22   LOC338758   XM_378371   This record was removed as a result of standard genome annotation proce
2.32    LOC338829   XM_292122   This record was removed as a result of standard genome annotation proce
-2.98   LOC340359   XM_294387   This record was removed as a result of standard genome annotation proce
-2.97   LOC342969   XM_292824   This record was removed as a result of standard genome annotation proce
-2.00   LOC343474   XM_291584   This record was removed as a result of standard genome annotation proce
-3.06   LOC345645   XM_293923   This record was removed as a result of standard genome annotation proce
-2.78   LOC345711   XM_293937   This record was removed as a result of standard genome annotation proce
-3.05   LOC387777   XM_373503   This record was removed as a result of standard genome annotation proce
-3.28   LOC387832   XM_370674   This record was removed as a result of standard genome annotation proce
2.36    LOC387888   XM_373550   This record was removed as a result of standard genome annotation proce
2.54    LOC387917   XM_373562   This record was removed as a result of standard genome annotation proce
2.20    LOC388123   XM_373628   This record was removed as a result of standard genome annotation proce
2.09    LOC388148   XM_370883   This record was removed as a result of standard genome annotation proce
-2.73   LOC388365   XM_373723   This record was removed as a result of standard genome annotation proce
-2.94   LOC388577   XM_373817   This record was removed as a result of standard genome annotation proce
-2.18   LOC388667   XM_373858   NM_001013643.1 was permanently suppressed because currently there is
-2.41   LOC388752   XM_373894   This record was removed as a result of standard genome annotation proce
-2.99   LOC388965   XM_371504   NM_001013648.3 was permanently suppressed because it is now thought
2.25    LOC389143   XM_374047   This record was removed as a result of standard genome annotation proce
-3.69   LOC389270   XM_374112   This record was removed as a result of standard genome annotation proce
-2.35   LOC389490   XM_371901   This record was removed as a result of standard genome annotation proce
-3.11   LOC389659   XM_374270   This record was removed as a result of standard genome annotation proce
-3.41   LOC389660   XM_372042   This record was removed as a result of standard genome annotation proce
-2.66   LOC389753   XM_372112   This record was removed as a result of standard genome annotation proce
2.03    LOC389764   XM_372121   This record was removed as a result of standard genome annotation proce
1.98    LOC390680   XM_372611   This record was removed as a result of standard genome annotation proce
-3.73   LOC391767   XM_373078   uncharacterized LOC391767
-2.27   LOC391769   XM_373079   This record was removed as a result of standard genome annotation proce
2.19    LOC392222   XM_373253   This record was removed as a result of standard genome annotation proce
-2.95   LOC392790   XM_374751   This record was removed as a result of standard genome annotation proce
2.54    LOC399898   XM_374885   NM_001013666.1 was permanently suppressed because it is now thought
2.93    LOC400070   XM_378381   This record was removed as a result of standard genome annotation proce
-3.34   LOC400201   XM_378449   This record was removed as a result of standard genome annotation proce
-3.25   LOC400433   XM_378538   This record was removed as a result of standard genome annotation proce
-2.62   LOC400740   XM_378840   This record was removed as a result of standard genome annotation proce
-2.48   LOC400958   XM_379100   This record was removed as a result of standard genome annotation proce
2.14    LOC401081   XM_379206   This record was removed as a result of standard genome annotation proce
-2.06   LOC401264   XM_379417   This record was removed as a result of standard genome annotation proce
-2.73   LOC401328   XM_379485   This record was removed as a result of standard genome annotation proce
-2.21   LOC401399   XM_379517   This record was removed as a result of standard genome annotation proce
-3.76   LOC401497   XM_376822   This record was removed as a result of standard genome annotation proce
2.62    LOC401509   XM_376841   NM_001032297.1: This RefSeq was permanently suppressed because it is
-2.82   LOC401528   XM_379642   This record was removed as a result of standard genome annotation proce
-2.35   LOC401529   XM_376872   This record was removed as a result of standard genome annotation proce
2.15    LOC401819   XM_377388   This record was removed as a result of standard genome annotation proce
-2.84   LOC402160   XM_377828   This record was removed as a result of standard genome annotation proce
-4.52   LOC402245   XM_377926   This record was removed as a result of standard genome annotation proce
-3.03   LOC402455   XM_374713   This record was removed as a result of standard genome annotation proce
2.61    LOC402509   XM_379840   This record was removed as a result of standard genome annotation proce
-3.03   LOC402578   XM_380135   This record was removed as a result of standard genome annotation proce
-2.57   LOC402681   XM_380025   This record was removed as a result of standard genome annotation proce
-2.55   LOC84856    NM_032770   NM_032770.3 was permanently suppressed because currently there is su
-2.87   LOC91632    XM_039721   NM_001080422.1: This RefSeq was permanently suppressed because it is
-2.79   LOC91948    XM_378549   This record was removed as a result of standard genome annotation proce
3.67    LOC93463    XM_376186   This record was removed as a result of standard genome annotation proce
-3.35   LOC96610    NM_080926   NM_080926.1 was permanently suppressed because currently there is su
2.93    LRP12       NM_013437                                   receptor activity
                                Low-density lipoprotein receptor-related protein 12;LRP12;ortholog
-6.18   LTA         NM_000595   Lymphotoxin-alpha;LTA;ortholog  tumor necrosis factor receptor binding;cytok
-2.01   LU          NM_005581                                   receptor activity
                                Lutheran blood group glycoprotein;BCAM;ortholog
-2.28   MAGEA12     NM_005367   Melanoma-associated antigen 12;MAGEA12;ortholog
-2.06   MAP3K6      NM_004672                                   protein kinase activity
                                Mitogen-activated protein kinase kinase kinase 6;MAP3K6;ortholog
-2.54   MAT2A       NM_005911                                   nucleotidyltransferase activity
                                S-adenosylmethionine synthetase isoform type-2;MAT2A;ortholog
-3.00   MDK         NM_002391   Midkine;MDK;ortholog            cytokine activity
2.19    MDM4        NM_002393   Protein Mdm4;MDM4;orthologubiquitin-protein ligase activity
-2.58   MED9        NM_018019   Mediator of RNA polymerase II transcription subunit 9;MED9;ortholog
2.48    MFAP5       NM_003480   Microfibrillar-associated protein 5;MFAP5;ortholog
2.61    MGC23284    XM_378628   This record was removed as a result of standard genome annotation proce
-2.39   MGC9515     XM_375313   This record was removed as a result of standard genome annotation proce
-3.30   MLANA       NM_005511   Melanoma antigen recognized by T-cells 1;MLANA;ortholog
2.46    MLC1SA      NM_002475                                   structural
                                Myosin light chain 6B;MYL6B;ortholog constituent of cytoskeleton;calcium
2.25    MLKL        NM_152649                                   protein kinase activity
                                Mixed lineage kinase domain-like protein;MLKL;ortholog
-2.32   MLLT4       NM_005936   Afadin;MLLT4;ortholog           structural constituent of cytoskeleton;actin b
2.52    MMP21       NM_147191                                   metallopeptidase
                                Matrix metalloproteinase-21;MMP21;ortholog activity
2.80    MPHOSPH1    NM_016195                                   microtubule motor
                                M-phase phosphoprotein 1;MPHOSPH1;orthologactivity;structural constitu
1.99    MRPL32      NM_031903                                   structural constituent of ribosome;nucleic ac
                                39S ribosomal protein L32, mitochondrial;MRPL32;ortholog
-2.57   MRPL34      NM_023937   39S ribosomal protein L34, mitochondrial;MRPL34;ortholog
-2.23   MRPS12      NM_021107                                   structural constituent of ribosome;nucleic ac
                                28S ribosomal protein S12, mitochondrial;MRPS12;ortholog
1.96    MRPS18A     NM_018135                                   structural constituent of ribosome;nucleic ac
                                28S ribosomal protein S18a, mitochondrial;MRPS18A;ortholog
-3.24   MRPS26      NM_030811                                   structural constituent of ribosome;nucleic ac
                                28S ribosomal protein S26, mitochondrial;MRPS26;ortholog
2.23    MRPS27      NM_015084                                   structural constituent of ribosome;nucleic ac
                                28S ribosomal protein S27, mitochondrial;MRPS27;ortholog
-2.94   MS4A1       NM_021950                                   receptor activity
                                B-lymphocyte antigen CD20;MS4A1;ortholog
-2.67   MTHFD2                                                oxidoreductase activity;hydrolase activity;lig
                   NM_006636 Methenyltetrahydrofolate cyclohydrolase;MTHFD2;ortholog
-2.17   MTIF2                                                 hydrolase activity;translation factor activity, n
                   NM_002453 Translation initiation factor IF-2, mitochondrial;MTIF2;ortholog
2.61    MTMR8      NM_017677  Myotubularin-related protein 8;MTMR8;ortholog
-2.45   MUC12      XM_379904 Mucin-12;MUC12;ortholog
-2.32   MVK        NM_000431 Mevalonate kinase;MVK;ortholog   kinase activity
2.27    MX2        NM_002463                                  GTPase Mx2;MX2;ortholog
                              Interferon-induced GTP-binding protein activity;structural constituent of cyto
2.32    MYCN                                                  transcription factor
                   NM_006316 N-myc proto-oncogene protein;MYCN;ortholog activity;transcription facto
2.13    MYEOV      NM_138768 Myeloma-overexpressed gene protein;MYEOV;ortholog
3.59    NARF                                                  oxidoreductase activity
                   NM_012336 Nuclear prelamin A recognition factor;NARF;ortholog
2.23    NAT8L      NM_178557 N-acetyltransferase 8-like protein;NAT8L;ortholog
2.18    NCOA5                                                 receptor activity
                   NM_020967 Nuclear receptor coactivator 5;NCOA5;ortholog
2.95    NDEL1      NM_030808  Nuclear distribution protein nudE-like 1;NDEL1;ortholog
-2.34   NDFIP1     NM_030571 NEDD4 family-interacting protein 1;NDFIP1;ortholog
2.31    NEGR1      NM_173808 Neuronal growth regulator 1;NEGR1;ortholog
3.19    NEURL                                                 ubiquitin-protein ligase activity
                   NM_004210 Neuralized-like protein 1;NEURL;ortholog
2.40    NFATC1     NM_006162                                  transcription factor activity;transcription
                              Nuclear factor of activated T-cells, cytoplasmic 1;NFATC1;ortholog facto
-2.25   NFIC                                                  transcription factor activity;transcription facto
                   NM_005597 Nuclear factor 1 C-type;NFIC;ortholog
2.05    NICAL                                                 structural homology of cytoskeleton;actin b
                   NM_022765 NEDD9-interacting protein with calponinconstituentand LIM domains;MICA
2.44    NOMO3                 Nodal modulator 3;NOMO3;ortholog
                   NM_001004067
-3.67   NOXA1                                                 oxidoreductase
                   NM_006647 NADPH oxidase activator 1;NOXA1;ortholog activity
-2.79   NPIP       NM_006985 Nuclear pore complex-interacting protein;NPIP;ortholog
2.96    NR0B2                                                 ligand-dependent nuclear receptor
                   NM_021969 Nuclear receptor subfamily 0 group B member 2;NR0B2;orthologactivity;tra
2.09    NR2F6      NM_005234                                  ligand-dependent nuclear receptor
                              Nuclear receptor subfamily 2 group F member 6;NR2F6;ortholog activity;tra
2.29    NRP2       NM_003872 Neuropilin-2;NRP2;ortholog oxidoreductase activity;serine-type peptidas
2.23    NSMAF      NM_003580 Protein FAN;NSMAF;orthologprotein binding
-3.42   NT5DC2                                                nucleotide phosphatase activity;nucleotide p
                   NM_022908 5'-nucleotidase domain-containing protein 2;NT5DC2;ortholog
2.02    NT5M       NM_020201 5'(3')-deoxyribonucleotidase, mitochondrial;NT5M;ortholog
2.25    NUDT22     NM_032344 Nucleoside diphosphate-linked moiety X motif 22;NUDT22;ortholog
-2.08   NUDT5                                                 pyrophosphatase
                   NM_014142 ADP-sugar pyrophosphatase;NUDT5;ortholog activity
-2.80   ODAG       NM_021167                                  transcription factor activity;transcription facto
                              GATA zinc finger domain-containing protein 1;GATAD1;ortholog
2.64    OKL38      NM_013370 Oxidative stress-induced growth inhibitor 1;OSGIN1;ortholog
-2.36   OR10H5     XM_210787 Olfactory receptor 10H5;OR10H5;ortholog
2.17    OR2T11                Olfactory receptor 2T11;OR2T11;ortholog
                   NM_001001964
2.44    OR4K17     XM_372504 Olfactory receptor 4K17;OR4K17;ortholog
2.14    OR5AP2                Olfactory receptor 5AP2;OR5AP2;ortholog
                   NM_001002925
2.18    OR6B1      XM_069621 Olfactory receptor 6B1;OR6B1;ortholog
-2.95   OR8G2      XM_370662 Olfactory receptor 8G2;OR8G2;ortholog
2.08    OVCA2                                                 transcription factor activity;transcription facto
                   NM_080822 Ovarian cancer-associated gene 2 protein;OVCA2;ortholog
-2.58   OVTN       NM_198185 Ovochymase-2;OVCH2;ortholog      serine-type peptidase activity
2.53    PABPC1     NM_002568                                   1;PABPC1;ortholog
                              Polyadenylate-binding protein RNA binding
-2.47   PACSIN2    NM_007229 Protein kinase C and casein kinase substrate in neurons protein 2;PACSI
2.46    PAFAH1B1                                              hydrolase IB subunit alpha;PAFAH1B1;orth
                   NM_000430 Platelet-activating factor acetylhydrolaseactivity, acting on ester bonds
2.10    PAFAH2     NM_000437                                  hydrolase 2, cytoplasmic;PAFAH2;ortholog
                              Platelet-activating factor acetylhydrolaseactivity, acting on ester bonds
-2.63   PAIP2B     XM_376062 Polyadenylate-binding protein-interacting protein 2B;PAIP2B;ortholog
-1.96   PAK1IP1                                               protein binding;kinase inhibitor activity;kinas
                   NM_017906 p21-activated protein kinase-interacting protein 1;PAK1IP1;ortholog
-4.28   PARC       NM_015089  CCL18(4-69);CCL18;ortholog chemokine activity
2.35    PARP1                                                 transferase activity,
                   NM_001618 Poly [ADP-ribose] polymerase 1;PARP1;ortholog transferring glycosyl gro
-2.46   PARP6      NM_020214 Poly [ADP-ribose] polymerase 6;PARP6;ortholog
2.28    PASD1                                                 transcription factor activity;transcription facto
                   NM_173493 PAS domain-containing protein 1;PASD1;ortholog
2.22    PAX3       NM_000438                                  transcription
                              Paired box protein Pax-3;PAX3;ortholog factor activity;transcription facto
2.48    PCDH8      NM_002590 Protocadherin-8;PCDH8;ortholog   calcium ion binding
-4.48   PCTK2                                                 protein kinase activity
                   NM_002595 Serine/threonine-protein kinase PCTAIRE-2;PCTK2;ortholog
2.01    PDCD2L       NM_032346                                  transcription factor activity;transcription facto
                                 Programmed cell death protein 2-like;PDCD2L;ortholog
2.46    PDGFRB       NM_002609                                  transmembrane receptor protein kinase
                                 Beta-type platelet-derived growth factor receptor;PDGFRB;ortholog activ
-3.13   PDLIM2       NM_021630                                  structural constituent of cytoskeleton;actin b
                                 PDZ and LIM domain protein 2;PDLIM2;ortholog
2.02    PDXDC2       NM_199134                                  carboxy-lyase activity
                                 Pyridoxal-dependent decarboxylase domain-containing protein 2;PDXDC2
-2.05   PELP1        NM_014389   Proline-, glutamic acid- and leucine-rich protein 1;PELP1;ortholog
2.37    PENK         NM_006211                                  neuropeptide
                                 Met-enkephalin-Arg-Phe;PENK;ortholog hormone activity
2.15    PEX10        NM_002617   Peroxisome assembly protein 10;PEX10;ortholog
2.31    PEX12        NM_000286   Peroxisome assembly protein 12;PEX12;ortholog
2.56    PFTK1        NM_012395                                  protein kinase activity
                                 Serine/threonine-protein kinase PFTAIRE-1;PFTK1;ortholog
-2.46   PGGT1B       NM_005023                                  acyltransferase activity
                                 Geranylgeranyl transferase type-1 subunit beta;PGGT1B;ortholog
-2.18   PHF10        NM_018288                                  acetyltransferase activity;transcription factor
                                 PHD finger protein 10;PHF10;ortholog
-2.25   PHLDA1       NM_007350   Pleckstrin homology-like domain family A member 1;PHLDA1;ortholog
-3.60   PI4KAP2      NM_199345                                  kinase activity
                                 Putative phosphatidylinositol 4-kinase alpha-like protein P2;PI4KAP2;ortho
-2.49   PIGM         NM_145167                                  transferase activity, transferring glycosyl gro
                                 GPI mannosyltransferase 1;PIGM;ortholog
2.54    PKD2L1       NM_016112                                  ion channel activity
                                 Polycystic kidney disease 2-like 1 protein;PKD2L1;ortholog
-4.38   PKIA         NM_006823                                  protein binding;kinase inhibitor activity;kinas
                                 cAMP-dependent protein kinase inhibitor alpha;PKIA;ortholog
-1.98   PLA2G3       NM_015715                                  phospholipase activity;calcium ion binding;c
                                 Group 3 secretory phospholipase A2;PLA2G3;ortholog
-2.00   PLAG1        NM_002655                                  transcription
                                 Zinc finger protein PLAG1;PLAG1;ortholog factor activity;transcription facto
2.01    PLD4         NM_138790   Phospholipase D4;PLD4;ortholog phospholipase activity
-2.35   PLEKHA1      NM_021622   Pleckstrin homology domain-containing family A member 1;PLEKHA1;orth
2.17    PLEKHO2      NM_025201   Pleckstrin homology domain-containing family O member 2;PLEKHO2;orth
2.52    PLSCR2       NM_020359   Phospholipid scramblase 2;PLSCR2;ortholog
2.46    PLXNC1       NM_005761   Plexin-C1;PLXNC1;ortholog transmembrane receptor protein kinase activ
-2.89   PMCHL1       NM_031887                                  neuropeptide
                                 Pro-MCH-like protein 1;PMCHL1;ortholog hormone activity
-2.16   PML          NM_002675                                  ubiquitin-protein ligase activity
                                 Probable transcription factor PML;PML;ortholog
-2.72   PNKP         NM_007254                                  nucleotide kinase activity;nucleotide phosph
                                 Polynucleotide 5'-hydroxyl-kinase;PNKP;ortholog
-2.52   POLD4        NM_021173                                  DNA-directed DNA
                                 DNA polymerase delta subunit 4;POLD4;orthologpolymerase activity;nucle
-2.51   POLR2J       NM_006234                                  DNA-directed RNA polymerase activity;nucle
                                 DNA-directed RNA polymerase II subunit RPB11-a;POLR2J;ortholog
2.49    POPDC3       NM_022361   Popeye domain-containing protein 3;POPDC3;ortholog
2.70    POU2AF1      NM_006235   POU domain class 2-associating factor 1;POU2AF1;ortholog
2.90    POU5F2       NM_153216                                  transcription factor activity;transcription facto
                                 POU domain, class 5, transcription factor 2;POU5F2;ortholog
2.33    PPBP         NM_002704                                  chemokine activity
                                 Neutrophil-activating peptide 2(1-63);PPBP;ortholog
-2.30   PPFIBP2      XM_084578   Liprin-beta-2;PPFIBP2;ortholog
-2.88   PPP1R3D      NM_006242                                  protein binding;phosphatase regulator activit
                                 Protein phosphatase 1 regulatory subunit 3D;PPP1R3D;ortholog
-2.73   PPP2R1A      NM_014225                                  phosphoprotein phosphatase subunit A alph
                                 Serine/threonine-protein phosphatase 2A 65 kDa regulatoryactivity;phosph
-2.03   PRAMEF8      XM_372762   PRAME family member 8;PRAMEF8;ortholog
1.98    PREI3        NM_015387                                  protein binding;kinase activator activity;kinas
                                 Mps one binder kinase activator-like 3;MOBKL3;ortholog
-2.27   PRKCB        NM_002738                                  protein kinase
                                 Protein kinase C beta type;PRKCB;ortholog activity;calcium ion binding;ca
2.36    PRR16        NM_016644   Proline-rich protein 16;PRR16;ortholog
2.15    PRR7         NM_030567   Proline-rich protein 7;PRR7;ortholog
-3.37   PSAP         NM_002778   Saposin-D;PSAP;ortholog        protein binding;enzyme regulator activity
2.09    PTCH2        NM_003738                                  receptor activity
                                 Protein patched homolog 2;PTCH2;ortholog
2.16    PTCRA        NM_138296   Pre T-cell antigen receptor alpha;PTCRA;ortholog
2.93    PTPN12       NM_002835                                   non-receptor type 12;PTPN12;ortholog
                                 Tyrosine-protein phosphatase phosphoprotein phosphatase activity;phosph
2.69    PTPN22       NM_012411                                   non-receptor type 22;PTPN22;ortholog
                                 Tyrosine-protein phosphatase phosphoprotein phosphatase activity;phosph
2.55    PTPN23       NM_015466                                   non-receptor type 23;PTPN23;ortholog
                                 Tyrosine-protein phosphatase phosphoprotein phosphatase activity;phosph
2.35    PTPRU        NM_005704                                  phosphoprotein phosphatase activity;phosph
                                 Receptor-type tyrosine-protein phosphatase U;PTPRU;ortholog
2.45    QSCN6        NM_002826                                  oxidoreductase activity;protein disulfide isom
                                 Sulfhydryl oxidase 1;QSOX1;ortholog
-3.74   RAB11-FIP2   NM_014904   Rab11 family-interacting protein 2;RAB11FIP2;ortholog
2.33    RAB11B       NM_004218                                  GTPase activity;protein binding
                                 Ras-related protein Rab-11B;RAB11B;ortholog
-3.02   RAB40C       NM_021168                                  GTPase activity;protein binding
                                 Ras-related protein Rab-40C;RAB40C;ortholog
2.87    RAB7         NM_004637                                  GTPase activity;protein binding
                                 Ras-related protein Rab-7a;RAB7A;ortholog
-2.64   RAG1        NM_000448                                   endodeoxyribonuclease activity;nucleic acid
                                V(D)J recombination-activating protein 1;RAG1;ortholog
2.86    RAG1AP1     NM_018845   RAG1-activating protein 1;RAG1AP1;ortholog
-3.45   RAI16       NM_022749   UPF0518 protein FAM160B2;FAM160B2;ortholog
-2.31   RANBP3L     NM_145000                                   protein binding;small GTPase regulator activ
                                Ran-binding protein 3-like;RANBP3L;ortholog
2.51    RASA1       NM_002890                                   protein binding;small
                                Ras GTPase-activating protein 1;RASA1;ortholog GTPase regulator activ
2.84    RCAN1       NM_004414   Calcipressin-1;RCAN1;ortholog   receptor binding
2.58    RFXANK      NM_003721                                   transcription factor
                                DNA-binding protein RFXANK;RFXANK;ortholog activity;transcription facto
2.60    RFXAP       NM_000538   Regulatory factor X-associated protein;RFXAP;ortholog
-2.72   RHBDF1      NM_022450                                   serine-type peptidase activity
                                Rhomboid family member 1;RHBDF1;ortholog
-3.63   RING1       NM_002931                                   transcription factor
                                E3 ubiquitin-protein ligase RING1;RING1;orthologactivity;transcription facto
2.89    RIPX        NM_014961   Protein RUFY3;RUFY3;ortholog    transcription factor activity;transcription facto
2.04    RLN1        NM_006911                                   h
                                Relaxin A chain;RLN1;ortholog ormone activity
-6.09   RNF14       NM_004290                                   ubiquitin-protein ligase
                                E3 ubiquitin-protein ligase RNF14;RNF14;ortholog activity;transcription f
2.24    RNF141,ZNF230
                    NM_016422   RING finger protein 141;RNF141;ortholog
-2.26   RNF34       NM_025126                                   ubiquitin-protein ligase
                                E3 ubiquitin-protein ligase RNF34;RNF34;ortholog activity
-4.24   RNF38       NM_022781   RING finger protein 38;RNF38;ortholog
-3.29   RNF44       NM_014901   RING finger protein 44;RNF44;ortholog
2.25    RNGTT       NM_003800                                   nucleotidyltransferase activity
                                mRNA guanylyltransferase;RNGTT;ortholog
-2.79   RPL13AP17 NM_203308     ribosomal protein L13a pseudogene 17
2.69    RPS15       XM_376154                                   structural constituent of ribosome;nucleic ac
                                40S ribosomal protein S15;RPS15;ortholog
-2.03   RSC1A1      NM_006511                                   carbohydrate transmembrane transporter
                                Regulatory solute carrier protein family 1 member 1;RSC1A1;ortholog ac
-2.69   RTN4RL1     NM_178568                                   receptor activity
                                Reticulon-4 receptor-like 1;RTN4RL1;ortholog
-2.71   RWDD2       NM_033411   RWD domain-containing protein 2A;RWDD2A;ortholog
2.27    RYR1        NM_000540                                   receptor
                                Ryanodine receptor 1;RYR1;ortholog activity;ligand-gated ion channel ac
2.37    SALL3       NM_171999                                   transcription factor activity;transcription facto
                                Sal-like protein 3;SALL3;ortholog
2.39    SARM1       NM_015077                                   protein protein
                                Sterile alpha and TIR motif-containingbinding 1;SARM1;ortholog
-2.14   SATB1       NM_002971                                   transcription factor activity;transcription facto
                                DNA-binding protein SATB1;SATB1;ortholog
2.93    SBF2        NM_030962   Myotubularin-related protein 13;SBF2;ortholog
2.22    SCARB1      NM_005505                                   receptor activity
                                Scavenger receptor class B member 1;SCARB1;ortholog
-3.68   SCRG1       NM_007281   Scrapie-responsive protein 1;SCRG1;ortholog
2.25    SCYE1       NM_004757                                   aminoacyl-tRNA ligase activity
                                Endothelial monocyte-activating polypeptide 2;SCYE1;ortholog
2.60    SDSL        NM_138432                                   hydrolase
                                Serine dehydratase-like;SDSL;ortholog activity;hydro-lyase activity;racem
2.62    SEC14L1     NM_003003   SEC14-like protein 1;SEC14L1;ortholog
-1.98   SEC22L3     NM_004206                                   SNAP receptor activity
                                Vesicle-trafficking protein SEC22c;SEC22C;ortholog
-2.24   SEC23IP     NM_007190                                   phospholipase
                                SEC23-interacting protein;SEC23IP;ortholog activity
2.14    SELH        NM_170746   Selenoprotein H;SELH;ortholog
2.35    SELM        NM_080430   Selenoprotein M;SELM;ortholog
-3.52   SERPINB10 NM_005024     Serpin B10;SERPINB10;ortholog   protein binding;serine-type endopeptidase in
2.32    SERPINB4    NM_002974   Serpin B4;SERPINB4;ortholog     protein binding;serine-type endopeptidase in
-2.18   SFRS2       NM_003016                                   RNA 2;SFRS2;ortholog
                                Splicing factor, arginine/serine-rich splicing factor activity, transesterificatio
2.00    SFRS2IP     NM_004719   SFRS2-interacting protein;SFRS2IP;ortholog
2.49    SGEF        NM_015595   SH3 domain-containing guanine exchange factor;SGEF;ortholog
2.27    SH2D6       NM_198482                                   receptor binding
                                SH2 domain-containing protein 6;SH2D6;ortholog
2.18    SH3MD1      XM_374831   SH3 and PX domain-containing protein 2A;SH3PXD2A;ortholog
-3.91   SHARPIN     NM_030974   Sharpin;SHARPIN;ortholog ubiquitin-protein ligase activity
2.90    SHB         NM_003028   SH2 domain-containing adapter protein B;SHB;ortholog
2.21    SHPRH       NM_173082                                   DNA helicase activity;nucleic acid binding
                                E3 ubiquitin-protein ligase SHPRH;SHPRH;ortholog
-2.60   SIAT7E      NM_030965                                   transferase activity, transferring glycosyl gro
                                Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;ST6GALNAC
-4.00   SIGIRR      NM_021805                                   cytokine receptor
                                Single Ig IL-1-related receptor;SIGIRR;ortholog activity
-3.14   SIPA1       NM_006747                                   protein binding;small GTPase regulator activ
                                Signal-induced proliferation-associated protein 1;SIPA1;ortholog
2.44    SIRPA       NM_080792                                    non-receptor type
                                Tyrosine-protein phosphatase chemokine activity substrate 1;SIRPA;ortholo
2.12    SIRT3       NM_012239                                   deacetylase activity;nucleic acid binding;chr
                                NAD-dependent deacetylase sirtuin-3, mitochondrial;SIRT3;ortholog
2.65    SLA        NM_006748                                    r
                               SRC-like-adapter;SLA;orthologeceptor binding
-2.29   SLA2       NM_032214   Src-like-adapter 2;SLA2;ortholog receptor binding
-2.50   SLC12A7    NM_006598                                    cation transmembrane
                               Solute carrier family 12 member 7;SLC12A7;orthologtransporter activity
-2.64   SLC25A26   NM_173471   S-adenosylmethionine mitochondrial carrier protein;SLC25A26;ortholog
2.18    SLC2A2     NM_000340                                    carbohydrate transmembrane transporter ac
                               Solute carrier family 2, facilitated glucose transporter member 2;SLC2A2;o
2.39    SLC39A4    NM_017767                                    transmembrane transporter activity
                               Zinc transporter ZIP4;SLC39A4;ortholog
3.32    SLC6A15    NM_018057                                    cation transmembrane transporter activity
                               Orphan sodium- and chloride-dependent neurotransmitter transporter NTT7
-2.39   SLFN12     NM_018042   Schlafen family member 12;SLFN12;ortholog
3.06    SLITRK4    NM_173078                                    receptor activity
                               SLIT and NTRK-like protein 4;SLITRK4;ortholog
2.09    SMAD6      NM_005585                                    transcription 6;SMAD6;ortholog
                               Mothers against decapentaplegic homolog factor activity;transcription facto
2.55    SMAP-1     NM_018671   Protein unc-45 homolog A;UNC45A;ortholog
-2.29   SMAP2      NM_022733                                    nucleic acid binding;protein
                               Stromal membrane-associated protein 2;SMAP2;ortholog binding;small GT
2.26    SMPX       NM_014332   Small muscular protein;SMPX;ortholog
-2.72   SNX16      NM_022133   Sorting nexin-16;SNX16;ortholog  kinase activity
-2.42   SOM        NM_021180                                    transcription factor activity;transcription facto
                               Grainyhead-like protein 3 homolog;GRHL3;ortholog
2.77    SORL1      NM_003105                                    receptor activity;transmembrane transporter
                               Sortilin-related receptor;SORL1;ortholog
2.60    SOX10      NM_006941                                    transcription factor activity;transcription facto
                               Transcription factor SOX-10;SOX10;ortholog
2.61    SOX9       NM_000346                                    transcription
                               Transcription factor SOX-9;SOX9;ortholog factor activity;transcription facto
3.85    SP1        NM_138473                                    transcription factor activity;transcription facto
                               Transcription factor Sp1;SP1;ortholog
2.28    SP4        NM_003112                                    transcription factor activity;transcription facto
                               Transcription factor Sp4;SP4;ortholog
2.18    SPAG6      NM_012443                                    structural constituent of cytoskeleton
                               Sperm-associated antigen 6;SPAG6;ortholog
2.44    SPATA24    XM_114430   Spermatogenesis-associated protein 24;SPATA24;ortholog
-2.17   SPIN3      XM_093024   Spindlin-3;SPIN3;ortholog
-2.97   SR-A1      NM_021228   Splicing factor, arginine/serine-rich 19;SCAF1;ortholog
-2.43   SRR        NM_021947                                    h
                               Serine racemase;SRR;orthologydrolase activity;hydro-lyase activity;racem
2.24    STK10      NM_005990                                    protein kinase activity
                               Serine/threonine-protein kinase 10;STK10;ortholog
2.24    STK11      NM_000455                                    protein kinase activity
                               Serine/threonine-protein kinase 11;STK11;ortholog
2.22    STK11IP    NM_052902   Serine/threonine kinase 11-interacting protein;STK11IP;ortholog
-2.89   SUPT3H     NM_003599                                     SPT3 homolog;SUPT3H;ortholog
                               Transcription initiation protein transcription factor activity;transcription facto
2.37    SVEP1      AK023591    Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing
2.98    TCIRG1     NM_006019                                    cation transmembrane transporter activity;hy
                               V-type proton ATPase 116 kDa subunit a isoform 3;TCIRG1;ortholog
2.47    TCN2       NM_000355   Transcobalamin-2;TCN2;ortholog   cation transmembrane transporter activity
2.51    TENR       NM_139243                                    hydrolase activity;deaminase activity;DNA b
                               Adenosine deaminase domain-containing protein 1;ADAD1;ortholog
2.65    TFCP2      NM_005653                                    transcription factor activity;transcription facto
                               Alpha-globin transcription factor CP2;TFCP2;ortholog
2.66    TGFB1      NM_000660                                    growth factor activity
                               Latency-associated peptide;TGFB1;ortholog
2.56    THEX1      NM_153332                                    exoribonuclease activity;nucleic acid binding
                               Histone mRNA 3'-exonuclease 1;THEX1;ortholog
-2.34   THRAP4     NM_014815                                    receptor activity
                               Mediator of RNA polymerase II transcription subunit 24;MED24;ortholog
-3.00   TIF1       NM_003852                                    ubiquitin-protein ligase activity;transcription f
                               Transcription intermediary factor 1-alpha;TRIM24;ortholog
2.17    TIMM10     NM_012456   Mitochondrial import inner membrane translocase subunit Tim10;TIMM10;
2.44    TIMM13     NM_012458   Mitochondrial import inner membrane translocase subunit Tim13;TIMM13;
3.06    TIMM8B     NM_012459                                    cation transmembrane transporter activity
                               Mitochondrial import inner membrane translocase subunit Tim8 B;TIMM8B
2.66    TKTL2      NM_032136                                    transketolase
                               Transketolase-like protein 2;TKTL2;ortholog activity
2.45    TLK2       NM_006852                                    protein kinase activity
                               Serine/threonine-protein kinase tousled-like 2;TLK2;ortholog
2.03    TLR9       NM_017442                                    receptor activity
                               Toll-like receptor 9;TLR9;ortholog
2.41    TM4SF18    NM_138786   Transmembrane 4 L6 family member 18;TM4SF18;ortholog
-2.36   TMCC2      NM_014858   Transmembrane and coiled-coil domains protein 2;TMCC2;ortholog
-2.68   TMEM106A   NM_145041   Transmembrane protein 106A;TMEM106A;ortholog
2.37    TMEM139    NM_153345   Transmembrane protein 139;TMEM139;ortholog
2.26    TMEM140    NM_018295   Transmembrane protein 140;TMEM140;ortholog
2.80    TMEM14B    NM_030969   Transmembrane protein 14B;TMEM14B;ortholog
2.47    TMEM150    NM_153342   Transmembrane protein 150;TMEM150;ortholog
2.52    TMEM16D    NM_178826   Anoctamin-4;ANO4;ortholog
2.26    TMEM179B NM_199337     Transmembrane protein 179B;TMEM179B;ortholog
2.54    TMEM203    NM_053045   Transmembrane protein 203;TMEM203;ortholog
3.47    TMEM69     NM_016486   Transmembrane protein 69;TMEM69;ortholog
2.59    TMF1       NM_007114   TATA element modulatory factor;TMF1;ortholog
2.28    TNFRSF8    NM_001243                                   receptor activity
                               Tumor necrosis factor receptor superfamily member 8;TNFRSF8;ortholog
2.98    TNNC1      NM_003280                                    cardiac muscles;TNNC1;ortholog
                               Troponin C, slow skeletal andstructural constituent of cytoskeleton;calcium
-3.14   TNNI2      NM_003282                                   structural constituent of cytoskeleton;actin b
                               Troponin I, fast skeletal muscle;TNNI2;ortholog
2.82    TNPO2      NM_013433   Transportin-2;TNPO2;orthologtransmembrane transporter activity
3.15    TNRC11     NM_005120                                   transcription factor activity;transcription facto
                               Mediator of RNA polymerase II transcription subunit 12;MED12;ortholog
2.64    TNT        NM_182831                                   motor activity;structural constituent of cytosk
                               Troponin T, slow skeletal muscle;TNNT1;ortholog
-3.59   TOMM34     NM_006809   Mitochondrial import receptor subunit TOM34;TOMM34;ortholog
-3.31   TOX        XM_376776                                   transcription factor activity;chromatin binding
                               Thymocyte selection-associated high mobility group box protein TOX;TOX
2.64    TP53BP1    NM_005657                                   transcription factor activity;transcription facto
                               Tumor suppressor p53-binding protein 1;TP53BP1;ortholog
2.09    TP73       NM_005427   Tumor protein p73;TP73;ortholog transcription factor activity;transcription facto
-2.82   TRAF2      NM_021138                                   receptor binding
                               TNF receptor-associated factor 2;TRAF2;ortholog
2.41    TRAPPC3    NM_014408   Trafficking protein particle complex subunit 3;TRAPPC3;ortholog
-2.62   TRIM25     NM_005082                                   ubiquitin-protein ligase
                               Tripartite motif-containing protein 25;TRIM25;orthologactivity
-2.70   TRIM28     NM_003449                                   ubiquitin-protein ligase activity;transcription f
                               Transcription intermediary factor 1-beta;TRIM28;ortholog
-2.92   TRIM28     NM_005762                                   ubiquitin-protein ligase activity;transcription f
                               Transcription intermediary factor 1-beta;TRIM28;ortholog
2.41    TRIM52     NM_032765                                   ubiquitin-protein ligase
                               Tripartite motif-containing protein 52;TRIM52;orthologactivity
2.32    TRPC3      NM_003305                                   ion           3;TRPC3;ortholog
                               Short transient receptor potential channel activity
-2.05   TSCOT      NM_033051   Thymic stromal cotransporter homolog;SLC46A2;ortholog
-2.33   TTC1       NM_003314   Tetratricopeptide repeat protein 1;TTC1;ortholog
-2.99   TTC30B     NM_152517   Tetratricopeptide repeat protein 30B;TTC30B;ortholog
3.50    TTLL6      NM_173623                                   ligase activity;structural constituent of cytos
                               Tubulin polyglutamylase TTLL6;TTLL6;ortholog
-2.10   TUBA3E     NM_207312                                   structural constituent of cytoskeleton
                               Tubulin alpha-3E chain;TUBA3E;ortholog
2.20    TXK        NM_003328                                   non-membrane spanning protein tyrosine kin
                               Tyrosine-protein kinase TXK;TXK;ortholog
-3.60   UBCE7IP5   NM_014948   RING finger protein 37;UBOX5;ortholog
3.39    UBE2J1     NM_016021                                    E2 J1;UBE2J1;ortholog
                               Ubiquitin-conjugating enzyme ligase activity
-2.47   UBE2J2     NM_058167                                    E2 J2;UBE2J2;ortholog
                               Ubiquitin-conjugating enzyme ubiquitin-protein ligase activity
2.08    UBXN2B     XM_059929   UBX domain-containing protein 2B;UBXN2B;ortholog
-2.80   UHRF1      NM_013282                                   transcription factor activity;transcription facto
                               E3 ubiquitin-protein ligase UHRF1;UHRF1;ortholog
3.34    UIMC1      NM_016290   Ubiquitin interaction motif-containing protein 1;UIMC1;ortholog
-2.28   UNQ9373    NM_207314   This record was removed by RefSeq staff; the sequence does not appear t
-3.14   UPK1A      NM_007000   Uroplakin-1a;UPK1A;ortholog
-6.64   USP10      NM_005153                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 10;USP10;ortholog
-2.84   USP13      NM_003940                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 13;USP13;ortholog
-2.99   USP20      NM_006676                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 20;USP20;ortholog
-3.64   USP24      XM_165973                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 24;USP24;ortholog
-4.99   USP46      NM_022832                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 46;USP46;ortholog
2.32    USP5       NM_003481                                   cysteine-type peptidase
                               Ubiquitin carboxyl-terminal hydrolase 5;USP5;ortholog activity
2.42    USP51      NM_201286                                   cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 51;USP51;ortholog
-2.93   USP9Y,USP10NM_004654                                   cysteine-type peptidase activity
                               Probable ubiquitin carboxyl-terminal hydrolase FAF-Y;USP9Y;ortholog
-2.32   VENTX2     NM_014468                                   transcription
                               Homeobox protein VENTX;VENTX;orthologfactor activity;transcription facto
3.73    VPS16      NM_022575   Vacuolar protein sorting-associated protein 16 homolog;VPS16;ortholog
2.22    VSTM2A     NM_182546   V-set and transmembrane domain-containing protein 2A;VSTM2A;ortholog
-2.66   VSTM2B     XM_292785                                   receptor activity
                               V-set and transmembrane domain-containing protein 2B;VSTM2B;ortholog
2.42    WBSCR16    NM_030798                                   protein binding;small protein;WBSCR16;orth
                               Williams-Beuren syndrome chromosomal region 16GTPase regulator activ
2.43    WBSCR28    NM_182504   Williams-Beuren syndrome chromosomal region 28 protein;WBSCR28;orth
2.84    WDFY3      NM_014991                                   protein binding
                               WD repeat and FYVE domain-containing protein 3;WDFY3;ortholog
2.67    WDR87      XM_371164   WD repeat-containing protein 87;WDR87;ortholog
2.49    WDR88      NM_173479   WD repeat-containing protein 88;WDR88;ortholog
2.19    WISP1     NM_003882                                 growth factor activity
                              WNT1-inducible-signaling pathway protein 1;WISP1;ortholog
3.30    WNT16     NM_016087   Protein Wnt-16;WNT16;ortholog receptor binding
2.10    WNT2B     NM_004185   Protein Wnt-2b;WNT2B;ortholog receptor binding
3.10    WSB1      NM_134264   WD repeat and SOCS box-containing protein 1;WSB1;ortholog
-3.08   WWP1      NM_007013                                 ubiquitin-protein ligase activity
                              NEDD4-like E3 ubiquitin-protein ligase WWP1;WWP1;ortholog
2.40    YIPF6     NM_173834   Protein YIPF6;YIPF6;ortholog
-2.10   ZC3H12D   XM_291154                                 nucleic acid binding
                              Zinc finger CCCH domain-containing protein 12D;ZC3H12D;ortholog
2.31    ZDHHC4    NM_018106   Probable palmitoyltransferase ZDHHC4;ZDHHC4;ortholog
-3.29   ZFX       NM_003410                                 transcription factor
                              Zinc finger X-chromosomal protein;ZFX;ortholog activity;transcription facto
-2.91   ZMYND11   NM_006624                                 transcription factor activity;transcription
                              Zinc finger MYND domain-containing protein 11;ZMYND11;ortholog facto
-2.85   ZNF140    NM_003440                                 transcription
                              Zinc finger protein 140;ZNF140;ortholog factor activity;transcription facto
3.29    ZNF187    NM_152736                                 transcription
                              Zinc finger protein 187;ZNF187;ortholog factor activity;transcription facto
2.57    ZNF24     NM_006965                                 transcription factor activity;transcription facto
                              Zinc finger protein 24;ZNF24;ortholog
-2.33   ZNF266    NM_006631                                 transcription
                              Zinc finger protein 266;ZNF266;ortholog factor activity;transcription facto
1.97    ZNF281    NM_012482                                 transcription
                              Zinc finger protein 281;ZNF281;ortholog factor activity;transcription facto
2.41    ZNF354C   NM_014594                                 transcription
                              Zinc finger protein 354C;ZNF354C;ortholog factor activity;transcription facto
-2.45   ZNF426    NM_024106                                 transcription
                              Zinc finger protein 426;ZNF426;ortholog factor activity;transcription facto
-2.15   ZNF543    NM_213598                                 transcription
                              Zinc finger protein 543;ZNF543;ortholog factor activity;transcription facto
2.91    ZNF673    NM_017776   Protein ZNF673;ZNF673;orthologtranscription factor activity;transcription facto
-2.58   ZNF750    NM_024702   Protein ZNF750;ZNF750;ortholog
-2.36   ZNF837    XM_375665                                 transcription
                              Zinc finger protein 837;ZNF837;ortholog factor activity;transcription facto
1.96    ZPLD1     NM_175056   Zona pellucida-like domain-containing protein 1;ZPLD1;ortholog
-4.21   ZSWIM5    XM_046581   Zinc finger SWIM domain-containing protein 5;ZSWIM5;ortholog
             GO Biological Process           GO Cellular Component Panther Protein Class
                                                                           cytokine;serine protease inhibitor
             immune system process;signal transduction;cell-cell signaling;proteolysis;signal transduction;cell-cell signaling
             fatty acid metabolic process                                  ligase
                                                                             toxin
             immune system process;extracellular transport;response toATP-binding cassette (ABC) transporter
                                                                             toxin
             immune system process;extracellular transport;response toATP-binding cassette (ABC) transporter
                                                                           ATP-binding cassette (ABC) transporter
             immune system process;extracellular transport;carbohydrate metabolic process;response to toxin
             lipid transport;lipid metabolic process                       transporter
             lipid transport;lipid metabolic process                       transporter
                                                                           transferase;dehydrogenase
             respiratory electron transport chain;acyl-CoA metabolic process;acyl-CoA metabolic process
             proteolysis                                                   metalloprotease;metalloprotease
             fatty acid beta-oxidation                                     oxidase
                                                                           protein phosphatase;protein phosphatase
             transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
             fatty acid metabolic process                                  ligase
                                                                           serine/threonine protein kinase receptor;TGF-beta receptor;
             cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protei
                                                                           serine/threonine protein kinase receptor;TGF-beta receptor;
             cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protei
                                                                           metalloprotease;metalloprotease
             signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
             cellular amino acid biosynthetic process                      decarboxylase
             cyclic nucleotide metabolic process                           adenylate cyclase
                                                                           ligase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

             regulation of transcription from RNA polymerase II promotertranscription cofactor
             transport                                                    transfer/carrier protein
             transport;mesoderm development                               transfer/carrier protein
                                                                          reductase
             immune system process;respiratory electron transport chain;ferredoxin metabolic process;oxygen and reactive oxygen
             protein targeting;signal transduction;signal transduction    signaling molecule
                                                                          kinase activator
             protein targeting;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling path
             metabolic process                                            dehydrogenase
             immune system process;lipid metabolic process                oxygenase
                                                                          protein
             phosphate metabolic process;protein amino acid phosphorylation kinase;protein kinase
hagy protein 1;AMBRA1;ortholog
             proteolysis
             glycogen metabolic process                                   amylase
                                                                          signaling molecule;kinase modulator
             transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein tyrosine kinase sig
             mesoderm development;angiogenesis                            signaling molecule
NKRD43;ortholog
hosphatase inhibitor activity;phosphatase regulator activity              phosphatase inhibitor
             intracellular protein transport;pinocytosis                  membrane traffic protein
             lipid transport;lipid metabolic process                      transporter;apolipoprotein
             blood circulation;lipid transport;lipid metabolic process    transporter;apolipoprotein
             lipid transport;cholesterol metabolic process                transporter;apolipoprotein
                                                                          nucleic acid binding;G-protein modulator
             G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa
             transport                                                    transporter

                                                                         growth factor
           signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
           proteolysis                                                   cysteine protease;cysteine protease
 HGEF17;ortholog
                                                                         guanyl-nucleotide exchange factor
           neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein s
                                                                         chromatin/chromatin-binding maintenance of chromatin arc
           nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment orprotein
ARMCX3;ortholog
           nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                         enzyme modulator
           visual perception;sensory perception;intracellular protein transport;endocytosis;G-protein coupled receptor protein signa
                                                                      hydrolase
             sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process


                                                                           receptor;defense/immunity protein;cell adhesion molecule
             macrophage activation;intracellular protein transport;receptor-mediated endocytosis;signal transduction;cell-cell adhesi
                                                                           signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
n factor ATF-6 beta;ATF6B;ortholog

                                           proton-transporting ATP synthase synthase;hydrolase
                                                                          ATP acid metabolic process
            cation transport;nucleobase, nucleoside, nucleotide and nucleic complex
            cation transport                                              ATP synthase
            cation transport                                              ATP synthase;nucleotide phosphatase;nucleotide phospha
            cation transport;purine base metabolic process                ATP synthase;hydrolase
            immune system process;mesoderm development;mammary gland development;cellular defense response
            signal transduction;signal transduction                       receptor
RD1;ortholog
                                                                           from RNA polymerase
            cell surface receptor linked signal transduction;transcriptiontranscription cofactor II promoter;cell surface receptor link


             cellular amino acid metabolic process                        methyltransferase;reductase
                                                                          membrane trafficking regulatory protein
             neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
             negative regulation of apoptosis                             protease inhibitor


                                                                         zinc finger II promoter;cell cycle
             cell cycle;DNA repair;regulation of transcription from RNA polymerase transcription factor
             neurological system process;synaptic transmission;synaptic transmission
                                                                         DNA repair;DNA recombination;establishment or maintenan
             regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
             mesoderm development;mammary gland development

0orf114;ortholog




14orf109;ortholog
                                                                          receptor linked signal transduction;carbohydrate metabolic
             visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
             negative regulation of apoptosis;protein modification processmethyltransferase




 orf95;ortholog

             proteolysis                                                  ubiquitin-protein ligase
 ein;UBE2CBP;ortholog
C6orf65;ortholog
             ion transport                                               ATP-binding cassette (ABC) transporter;carbohydrate trans


             mRNA processing;translation                                 mRNA processing factor;nuclease

            complement activation;response to stimulus                   complement component
GIN2;ortholog

             translation                                                 esterase




                                                                          voltage-gated calcium channel;voltage-gated ion channel
             muscle contraction;neurotransmitter secretion;neuromuscular synaptic transmission;nerve-nerve synaptic transmission
                                                                          cysteine apoptosis
             induction of apoptosis;induction of apoptosis;proteolysis;induction of protease;cysteine protease;annexin;calmodulin
             induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;I-kappaB kinase/NF-kappaB cascad
             neurological system process;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic tra

            neurological system process                                neuropeptide
                                                                       transcription factor;chromatin/chromatin-binding protein
            apoptosis;regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin arch
C134;ortholog
C42;ortholog




                                                                         chemokine
             immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
             mitosis;mitosis                                             kinase activator
                                          nucleus                        transcription cofactor;kinase activator
             cell cycle;RNA elongation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promote
                                                                         receptor;defense/immunity protein;cell adhesion molecule
             macrophage activation;cell adhesion;cell adhesion;cellular defense response
                                                                         immunoglobulin receptor superfamily;guanyl-nucleotide exc
             immune response;cell adhesion;cell motion;cell adhesion;response to stimulus
                                                                         membrane-bound signaling motion;signal transduction;cell-
             gamete generation;B cell mediated immunity;signal transduction;cell-cell adhesion;cell molecule;cell adhesion molecul

                                                                          protein phosphatase;protein phosphatase
             cell cycle;phosphate metabolic process;protein modification process;cell cycle
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;mesoderm developm
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system dev
CDK5RAP1;ortholog
                                                                           nucleic acid binding;G-protein modulator
               G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa
                                                                           calmodulin
               cell cycle;calcium-mediated signaling;cell cycle;calcium-mediated signaling
protein 1;CGRRF1;ortholog
               cholesterol metabolic process                               hydroxylase;oxidase
 igase activity                                                            ubiquitin-protein ligase

                                                                            G-protein modulator
              intracellular signaling cascade;intracellular signaling cascade
                                                                            G-protein modulator
              intracellular signaling cascade;intracellular signaling cascade
                                             nucleus                        transcription factor;DNA-directed DNA polymerase;chromat
              regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcription from RNA polymerase
                                                                            cation transporter;acetylcholine receptor;acetylcholine rece
              muscle contraction;sensory perception;cation transport;signal transduction;nerve-nerve synaptic transmission;neuromu
              sulfur metabolic process                                      transferase
ning protein 2;RSAD2;ortholog
uent of cytoskeleton                         cytoskeleton                   cytoskeletal protein
              muscle contraction;metabolic process                          amino acid kinase;amino acid kinase
              anion transport                                               anion channel
                                             tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                             tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                            anion channel;transferase
              immune system process;anion transport;oxygen and reactive oxygen species metabolic process;response to toxin
                                                                            membrane trafficking
              neurological system process;lysosomal transport;intracellular protein transport regulatory protein
              transport;proteolysis;protein folding                         chaperone
ontaining protein 1;CMTM1;ortholog
              cation transport;signal transduction;signal transduction      cyclic nucleotide-gated ion channel;voltage-gated potassium
              cation transport;signal transduction;signal transduction      cyclic nucleotide-gated ion channel;voltage-gated potassium

             regulation of transcription from RNA polymerase II promotertranscription factor
             regulation of transcription from RNA polymerase II promotertranscription factor;nucleic acid binding
                                             extracellular component morphogenesis;cellular component morphogenesis
             cellular component morphogenesis;cellularmatrix              extracellular matrix structural protein
                                             extracellular matrix         extracellular matrix structural protein
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;mesoderm developm


                                           extracellular matrix       extracellular matrix structural protein
             cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component
                                           extracellular component morphogenesis;cellular component morphogenesis
             cellular component morphogenesis;cellularmatrix          extracellular matrix structural protein

                                            actin cytoskeleton            non-motor actin binding protein
            intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular c
            proteolysis                                                   metalloprotease;metalloprotease
            proteolysis                                                   metalloprotease;metalloprotease
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
 RELD1;ortholog
n;CRIM1;ortholog
                                            actin cytoskeleton
            mesoderm development;muscle organ development                 actin family cytoskeletal protein
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway




                                                                         oxidase
             respiratory electron transport chain;steroid metabolic process
             translation                                                 ribosomal protein
                                                                         oxygenase
             respiratory electron transport chain;steroid metabolic process
                                                                         chemokine
             immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
             lipid transport;lipid metabolic process                     transfer/carrier protein;enzyme modulator
             cellular amino acid metabolic process                    decarboxylase
                                                                      RNA helicase;helicase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                      RNA helicase;helicase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

             respiratory electron transport chain;metabolic process       dehydrogenase
ransporter activity                                                       transporter

                                                                                      cascade;cell surface receptor
             cell surface receptor linked signal transduction;intracellular signaling molecule;enzyme modulator linked signal transd
                                                                            transmembrane receptor regulatory/adaptor protein
             neurological system process;cell surface receptor linked signal transduction;nerve-nerve synaptic transmission;cell sur
             neurological system process                                    transmembrane receptor regulatory/adaptor protein
             neurological system process                                    transmembrane receptor regulatory/adaptor protein
                                                                            dehydrogenase
             respiratory electron transport chain;cellular amino acid catabolic process;protein metabolic process

           nuclear mRNA splicing, via spliceosome                        RNA binding protein
mall GTPase regulator activity;guanyl-nucleotide exchange factor activityguanyl-nucleotide exchange factor
           proteolysis                                                   metalloprotease;metalloprotease
           proteolysis                                                   serine protease;serine protease
                                                                         hydrolase
           nucleobase, nucleoside, nucleotide and nucleic acid metabolic process


                                                                        protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                        protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein am
                                                                        homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development

             spermatogenesis                                           nucleic acid binding
                                                                       transcription factor;nucleic acid binding
             female gamete generation;cell cycle;signal transduction;DNA replication;regulation of transcription from RNA polymeras
                                                                       acetyltransferase;acyltransferase;dehydrogenase;hydratase
             coenzyme metabolic process;vitamin biosynthetic process;carbohydrate metabolic process;fatty acid beta-oxidation
                                                                       hydrolase;chaperone
             polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
             protein metabolic process                                 translation elongation factor
             translation                                               translation elongation factor
                                                                       membrane-bound signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein t
                                                                       membrane-bound signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein t

                                                                           KRAB box transcription factor;nucleic acid binding
            cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;ectoderm development;mesoderm dev
                                             actin cytoskeleton            non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
            cellular amino acid biosynthetic process;translation           translation initiation factor;isomerase
            translation                                                    translation initiation factor
            translation                                                    translation initiation factor
                                             ribonucleoprotein complex ribonucleoprotein
            mRNA 3'-end processing;ectoderm development;nervous system development
                                                                           transcription factor;signaling molecule
            immune system process;intracellular signaling cascade;transcription from RNA polymerase II promoter;intracellular sig
                                                                           acetyltransferase
            purine base metabolic process                                  nucleotide phosphatase;nucleotide phosphatase
                                                                           tyrosine protein kinase receptor;tyrosine protein kinase rece
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
                                                                           tyrosine protein kinase receptor;tyrosine protein kinase rece
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
                                                                           tyrosine protein kinase receptor;tyrosine protein kinase rece
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
            intracellular protein transport;vesicle-mediated transport     membrane traffic protein;G-protein modulator
                                                                           protein
            phosphate metabolic process;protein amino acid phosphorylation kinase;protein kinase
                                                                           oxidoreductase
            respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
ochondrial;ETFA;ortholog
                                                                           transcription factor;signaling molecule;nucleic acid binding
            cell surface receptor linked signal transduction;MAPKKK cascade;regulation of transcription from RNA polymerase II p
                                                                           glycosyltransferase
            polysaccharide metabolic process;protein amino acid glycosylation
            immune system process;proteolysis;blood coagulation            serine protease;serine protease
            tRNA aminoacylation for protein translation                    aminoacyl-tRNA synthetase
TKD1;ortholog
TKD5;ortholog

                                          extracellular matrix            signaling molecule;extracellular matrix glycoprotein;extrace
             visual perception;sensory perception;signal transduction;signal transduction;mesoderm development;skeletal system d
             proteolysis
             proteolysis
             proteolysis
             metabolic process
             mesoderm development;muscle organ development
                                                                          immunoglobulin receptor superfamily;immunoglobulin recep
             B cell mediated immunity;natural killer cell activation;macrophage activation;signal transduction;signal transduction;res
             transcription from RNA polymerase II promoter                zinc finger transcription factor
                                                                          growth factor
             neurological system process;transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;tran
                                                                          growth factor
             transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein tyrosine kinase sig

                                                                              signal transduction;MAPKKK cascade;JAK-STAT cascade
              negative regulation of apoptosis;cell surface receptor linked tyrosine protein kinase receptor;tyrosine protein kinase rece
                                                                              receptor linked signal transduction;carbohydrate metabolic
              visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
ecause currently there is support for the transcript but not for the protein.
 d genome annotation processing.
 d genome annotation processing.
ecause it is now thought that this gene is a pseudogene.


ecause it is a nonsense-mediated mRNA decay (NMD) candidate.
                                             actin cytoskeleton             non-motor actin binding protein
              cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                             extracellular matrix           receptor linked signal transduction
              cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
              respiratory electron transport chain;metabolic process        oxygenase
 ;FNDC5;ortholog
                                                                            receptor linked signal transduction;carbohydrate metabolic
              visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                            receptor linked signal transduction;carbohydrate metabolic
              visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                            receptor linked signal transduction;carbohydrate metabolic
              visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding
                                                                            receptor linked signal transduction;carbohydrate metabolic
              visual perception;sensory perception;cell cycle;cell surface transcription factor;nucleic acid binding


                                                                       enzyme modulator
             cellular amino acid catabolic process                     transferase;deaminase
             metabolic process                                         dehydrogenase
             immune system process;protein amino acid glycosylation glycosyltransferase
             cation transport                                          cation transporter
             cell cycle;proteolysis;cell cycle                         enzyme modulator
uent of cytoskeleton;microtubule binding microtubule                   non-motor microtubule binding protein
             transcription from RNA polymerase II promoter             transcription factor
                                                                       GABA receptor;GABA receptor
             neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;
B4GALNT2;ortholog
          monosaccharide metabolic process                              epimerase/racemase
          glycolysis                                                    dehydrogenase

                                                                         zinc finger development;mesoderm development;heart deve
            regulation of transcription from RNA polymerase II promoter;endoderm transcription factor;nuclease
            mesoderm development;muscle organ development                growth factor
                                                                         system development
            female gamete generation;mesoderm development;skeletal growth factor
                                                                         neurotrophic factor
            neurological system process;negative regulation of apoptosis;transmembrane receptor protein tyrosine kinase signaling
                                            gap junction
            signal transduction;signal transduction                      gap junction
                                            heterotrimeric pathway;G-protein
                                                                         heterotrimeric G-protein
            G-protein coupled receptor protein signaling G-protein complex coupled receptor protein signaling pathway
                                            heterotrimeric pathway;G-protein
                                                                         hydrolase;heterotrimeric G-protein
            G-protein coupled receptor protein signaling G-protein complex coupled receptor protein signaling pathway

            monosaccharide metabolic process                           isomerase;hydrolase
                                                                       G-protein coupled receptor
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway



                                                                          peroxidase
            immune system process;oxygen and reactive oxygen species metabolic process;steroid metabolic process;response t
                                                                          receptor linked receptor regulatory/adaptor protein
            cell surface receptor linked signal transduction;cell surface transmembranesignal transduction

            general transcription from RNA polymerase II promoter       transcription cofactor;nucleic acid binding
            transcription initiation from RNA polymerase II promoter    transcription factor;nucleic acid binding
            glycogen metabolic process                                  glycosyltransferase

                                        actin and nucleic           basic helix-loop-helix transcription factor;non-motor actin bi
            nucleobase, nucleoside, nucleotidecytoskeletonacid metabolic process;cellular component morphogenesis;cellular com

            proteolysis                                             ubiquitin-protein ligase
            meiosis;nuclear mRNA splicing, via spliceosome;meiosis DNA helicase;RNA helicase;mRNA splicing factor;helicase
                                        extracellular matrix        transporter;apolipoprotein;membrane-bound signaling molec
            immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp
            proteolysis                                             ubiquitin-protein ligase

hatase activity;nucleotide phosphatase activity                         nucleotide phosphatase;nucleotide phosphatase
             DNA repair                                                 damaged DNA-binding protein


                                        MHC protein complex           major
            antigen processing and presentation;cellular defense response histocompatibility complex antigen
                                        MHC protein complex           major antigen via MHC complex antigen
            antigen processing and presentation of peptide or polysaccharide histocompatibilityclass II;cellular defense response


                                                                       homeobox transcription factor;nucleic acid binding
            regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
            proteolysis                                                metalloprotease;metalloprotease
ER5L;ortholog

                                                                        interferon superfamily
            response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-m
            signal transduction;cell-matrix adhesion;signal transduction;cell-matrix adhesion
                                                                        kinase;kinase
                                                                        interleukin pathway;cell-cell signaling;cytokine-mediated sig
            immune response;macrophage activation;cytokine-mediated signaling superfamily
                                                                        type I pathway
            cytokine-mediated signaling pathway;cytokine-mediated signalingcytokine receptor
                                                                        type I cytokine receptor
            immune system process;cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                        type I pathway
            cytokine-mediated signaling pathway;cytokine-mediated signalingcytokine receptor

                                                                          type I cytokine cascade;MAPKKK cascade;cell-cell signa
            natural killer cell activation;cytokine-mediated signaling pathway;JAK-STATreceptor
                                                                               immunoglobulin receptor superfamily;immunoglobulin recep
              natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stim
              purine base metabolic process                                    dehydrogenase
              metabolic process                                                methyltransferase
              cell surface receptor linked signal transduction;proteolysis;cell surface receptor linked signal transduction
              immune system process                                            immunoglobulin receptor superfamily;immunoglobulin recep
              cytokine-mediated signaling pathway;transmembrane receptor protein tyrosine kinase signaling pathway;MAPKKK cas

                                                                       receptor
                                                                       voltage-gated
            muscle contraction;neuronal action potential propagation;cation transport potassium channel;voltage-gated ion channel
            cation transport                                           voltage-gated potassium channel;voltage-gated ion channel
            cation transport                                           voltage-gated potassium channel;voltage-gated ion channel
            cation transport                                           voltage-gated potassium channel;voltage-gated ion channel
ol-pentakisphosphate kinase 2;HISPPD1;ortholog




              cell motion                     extracellular matrix       extracellular matrix structural protein
              regulation of transcription from RNA polymerase II promoterKRAB box transcription factor

                                                                       lipase
                                                                       homeobox transcription factor;zinc finger transcription
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;gut mesoderm development;hemopoiesis facto

              gamete generation;apoptosis


              intracellular protein transport microtubule                microtubule binding motor protein
              mitosis;mitosis                 microtubule                microtubule binding motor protein
                                                                         glucosidase;glycosidase
              carbohydrate metabolic process;translation;protein modification process
                                              actin cytoskeleton         non-motor actin binding protein
              neurological system process;cellular component morphogenesis;cellular component morphogenesis;cellular componen

                                         intermediate component morphogenesis;cellular componentfilament
                                                                        structural protein;intermediate morphogenesis
              cellular component morphogenesis;cellularfilament cytoskeleton
                                         intermediate component morphogenesis;ectoderm development;cellular component morp
                                                                        structural protein;intermediate filament
              cellular component morphogenesis;cellularfilament cytoskeleton



            tRNA aminoacylation for protein translation                       aminoacyl-tRNA synthetase
                                                                              non-receptor tyrosine protein kinase;non-receptor tyrosine p
            female gamete generation;immune system process;carbohydrate transport;cell cycle;intracellular signaling cascade;ca
                                                                              transfer/carrier protein;isomerase
            muscle contraction;transport;intracellular signaling cascade;fatty acid biosynthetic process;steroid metabolic process;i
            regulation of transcription from RNA polymerase II promoternucleic acid binding
                                                                              immunoglobulin receptor superfamily;immunoglobulin recep
            natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stim
                                              actin cytoskeleton              structural protein;actin family cytoskeletal protein
            gamete generation;cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular compone
                                              cell junction                   cell junction protein;cell adhesion molecule
            neurological system process;cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morph
 uppressed because currently there is support for the transcript but not for the protein.
ecause currently there is support for the transcript but not for the protein.
                                                                              transcription cofactor
            transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                              actin cytoskeleton              non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;mesoderm development;cellular component mo
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
d because it is now thought that this gene is a pseudogene.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 tly suppressed because it is now thought that this gene does not encode a protein.
 d genome annotation processing.
ecause currently there is insufficient support for the transcript and the protein.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
d because currently there is support for the transcript but not for the protein.
 d genome annotation processing.
sequence does not appear to represent a valid product.

sequence does not appear to represent a valid product
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
d because currently there is insufficient support for the transcript and the protein.
 d genome annotation processing.
d because it is now thought that this gene is a pseudogene.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.

d genome annotation processing.
d genome annotation processing.
 d genome annotation processing.
d because it is now thought that this gene does not encode a protein.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 tly suppressed because it is now thought that this gene is a pseudogene.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
 d genome annotation processing.
ecause currently there is support for the transcript but not for the protein.
 tly suppressed because it is now thought that this gene is a pseudogene.
 d genome annotation processing.
 d genome annotation processing.
ecause currently there is support for the transcript but not for the protein.
                                                adhesion;cell adhesion
              female gamete generation;cellextracellular matrix               receptor;extracellular matrix glycoprotein
                                                                               of apoptosis;cytokine-mediated signaling pathway;cell-cell
              natural killer cell activation;macrophage activation;induction tumor necrosis factor family member
              cell adhesion;cell adhesion                                     receptor;immunoglobulin superfamily cell adhesion molecul
              gamete generation;apoptosis
                                                                              protein
              phosphate metabolic process;protein amino acid phosphorylation kinase;protein kinase
              cellular amino acid metabolic process                           nucleotidyltransferase
                                                                              cytokine
              signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
              negative regulation of apoptosis                                ubiquitin-protein ligase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                               extracellular matrix           extracellular matrix glycoprotein
 d genome annotation processing.
 d genome annotation processing.
ANA;ortholog
              muscle contraction               actin cytoskeleton             actin family cytoskeletal protein;calmodulin
              protein amino acid phosphorylation                              protein kinase;protein kinase
                                               actin cytoskeleton             non-motor actin binding protein
              signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component morphogenesis;cellular compon
              proteolysis                      extracellular matrix           metalloprotease;metalloprotease;extracellular matrix protein
                                               segregation
              mitosis;mitosis;chromosome microtubule                          microtubule binding motor protein
              translation                                                     ribosomal protein

              translation                                                 ribosomal protein
              translation                                                 ribosomal protein
              translation                                                 ribosomal protein
              translation                                                 ribosomal protein
                                                                            transduction;cell surface receptor linked signal transductio
              B cell mediated immunity;cell surface receptor linked signalreceptor
                                          mitochondrion;organelle        dehydrogenase;ligase;hydrolase
             purine base metabolic process;cellular amino acid biosynthetic process
             translation                                                 translation initiation factor;hydrolase
                                                                         phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process

                                                                         kinase;kinase
             cholesterol metabolic process;protein amino acid phosphorylation
                                             microtubule                 hydrolase;small GTPase;microtubule morphogenesis;cellul
             intracellular protein transport;endocytosis;cellular component morphogenesis;cellular component family cytoskeletal pr
                                                                         basic helix-loop-helix transcription factor;nucleic acid bindin
             induction of apoptosis;cell cycle;MAPKKK cascade;induction of apoptosis;regulation of transcription from RNA polyme

             respiratory electron transport chain                         dehydrogenase

                                                                        receptor
             regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process


                                                                      system development
             cell adhesion;cell adhesion;ectoderm development;nervous immunoglobulin superfamily cell adhesion molecule
                                                                      ubiquitin-protein ligase
             gamete generation;cell motion;ectoderm development;nervous system development
                                                                      transcription factor
             immune system process;regulation of transcription from RNA polymerase II promoter;mesoderm development;cellular d
             transcription from RNA polymerase II promoter            transcription factor;nucleic acid binding
                                           actin cytoskeleton         non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morp

             immune response;response to stimulus                        oxidase
             intracellular protein transport;nuclear transport
             regulation of transcription from RNA polymerase II promoternuclear hormone receptor;receptor;nucleic acid binding
                                                                         nuclear II promoter;signal transduction
             signal transduction;regulation of transcription from RNA polymerasehormone receptor;receptor
                                             extracellular matrix        transporter;apolipoprotein;membrane-bound signaling molec
             immune system process;visual perception;sensory perception;intracellular protein transport;endocytosis;vitamin transp
             protein targeting;signal transduction;signal transduction   enzyme modulator
             purine base metabolic process                               nucleotide phosphatase;nucleotide phosphatase

22;NUDT22;ortholog
            purine base metabolic process                              pyrophosphatase
            regulation of transcription from RNA polymerase II promotertranscription factor
GIN1;ortholog




or activity;transcription factor activity                                 transcription factor
               female gamete generation;fertilization;proteolysis         serine protease;serine protease
               mRNA polyadenylation                                       RNA binding protein
                                                                          membrane trafficking regulatory protein
               intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling cascade
                                                                          esterase
               transcription from RNA polymerase II promoter;ectoderm development;nervous system development
               immune system process;phospholipid metabolic process esterase
               mRNA polyadenylation
               transcription from RNA polymerase II promoter              kinase inhibitor
                                                                          chemokine
               immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-ce
                                                                          glycosyltransferase
               immune system process;DNA repair;protein amino acid ADP-ribosylation;response to stress

             regulation of transcription from RNA polymerase II promoterbasic helix-loop-helix transcription factor
                                                                          homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous syste
                                                                          cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;embryonic development
             mitosis;protein amino acid phosphorylation;mitosis           non-receptor serine/threonine protein kinase;non-receptor se
 or activity;transcription factor activity;transcription cofactor activity     transcription cofactor
                                                                               tyrosine protein kinase receptor;tyrosine protein kinase rece
                gamete generation;immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;protein
                                                actin cytoskeleton             non-motor actin binding protein
                muscle contraction;cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular compon
                cellular amino acid metabolic process                          decarboxylase
n 1;PELP1;ortholog
                                                                               neuropeptide
                neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein s
                intracellular protein transport;peroxisomal transport
                intracellular protein transport;peroxisomal transport          transfer/carrier protein
                mitosis;protein amino acid phosphorylation;mitosis             non-receptor serine/threonine protein kinase;non-receptor se
                protein amino acid lipidation                                  acyltransferase
                                                                               acetyltransferase;zinc finger transcription factor;chromatin/c
                induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;protein amino acid acetyla
mber 1;PHLDA1;ortholog
                                                                               kinase;kinase
                protein targeting;endocytosis;negative regulation of apoptosis;cell surface receptor linked signal transduction;negative r
                                                                               glycosyltransferase
                phospholipid metabolic process;protein amino acid lipidation;translation
                cation transport;endoderm development                          ion channel
                                                                               kinase inhibitor
                intracellular signaling cascade;intracellular signaling cascade;mesoderm development;muscle organ development
                lipid metabolic process                                        phospholipase;annexin;calmodulin
                regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
                lipid metabolic process                                        phospholipase
 A member 1;PLEKHA1;ortholog
 O member 2;PLEKHO2;ortholog
                                                                               transfer/carrier protein
                immune system process;lipid transport;phospholipid metabolic process;blood coagulation
                                                                               tyrosine protein kinase receptor;signaling molecule;tyrosine
                transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane
                                                                               neuropeptide
                signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                proteolysis                                                    ubiquitin-protein ligase
                DNA repair                                                     nucleotide kinase;nucleotide phosphatase;nucleotide kinas
                cell cycle;DNA replication;cell cycle                          nucleotidyltransferase;DNA-directed DNA polymerase
                general transcription from RNA polymerase II promoter          nucleotidyltransferase;DNA-directed RNA polymerase
                mesoderm development;heart development
 2AF1;ortholog
                regulation of transcription from RNA polymerase II promoter homeobox transcription factor
                                                                               chemokine
                response to interferon-gamma;macrophage activation;cytokine-mediated signaling pathway;JNK cascade;I-kappaB kina
                protein targeting
                glycogen metabolic process                                     phosphatase modulator
 hosphatase activity;phosphoprotein phosphatase activity                       protein phosphatase;protein phosphatase

              mitosis;cytokinesis;mitosis                              kinase activator
                                                                       non-receptor serine/threonine protein kinase;transfer/carrier
              calcium-mediated signaling;protein amino acid phosphorylation;calcium-mediated signaling


              lipid transport;lipid metabolic process                         enzyme modulator
                                                                              receptor
              lipid transport;intracellular protein transport;exocytosis;cell surface receptor linked signal transduction;lipid metabolic p

                                                                            protein phosphatase;protein phosphatase
              protein targeting;signal transduction;cell-cell adhesion;protein amino acid phosphorylation;cell motion;signal transductio
                                                                            protein phosphatase;protein phosphatase
              immune system process;protein targeting;cell surface receptor linked signal transduction;cell-matrix adhesion;cell-cell
                                                                            protein phosphatase;protein phosphatase
              cell cycle;cell surface receptor linked signal transduction;intracellular signaling cascade;protein amino acid phosphoryl
                                                                            receptor;protein phosphatase;protein phosphatase
              cell surface receptor linked signal transduction;cell-cell adhesion;protein amino acid phosphorylation;cell surface recep
                                                                            oxidase
              respiratory electron transport chain;protein modification process

                                                                          small GTPase
              intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                          small GTPase
              intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                          small GTPase
              intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling casca
                                                                    endodeoxyribonuclease;nuclease;hydrolase
             B cell mediated immunity;DNA recombination;response to stimulus


             protein targeting;nuclear transport                           G-protein modulator
             signal transduction;signal transduction                       G-protein modulator
                                                                           signaling molecule
             intracellular signaling cascade;intracellular signaling cascade;ectoderm development
                                                                           transcription factor
             antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;cellular defense response

             proteolysis                                                    serine protease;serine protease
             regulation of transcription from RNA polymerase II promoterzinc finger transcription factor
             transcription from RNA polymerase II promoter                  zinc finger transcription factor
                                                                            peptide hormone
             negative regulation of apoptosis;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane rec
                                                                            transcription cofactor;ubiquitin-protein metabolic process;in
             intracellular signaling cascade;regulation of transcription from RNA polymerase II promoter;proteinligase

             proteolysis                                                  ubiquitin-protein ligase


             mRNA capping                                                 nucleotidyltransferase;phosphatase;phosphatase

             translation                                                   ribosomal protein
                                                                           carbohydrate
             cation transport;carbohydrate transport;carbohydrate metabolic process transporter;cation transporter
                                             extracellular matrix          receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
                                                                           phosphatase;phosphatase
                                                                           ligand-gated ion channel;ligand-gated ion channel
             muscle contraction;cation transport;calcium-mediated signaling;calcium-mediated signaling
             regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;nucleic acid binding
             immune system process                                         enzyme modulator
             regulation of transcription from RNA polymerase II promoterhomeobox transcription factor;nucleic acid binding
                                                                           phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process
                                                                           receptor
             macrophage activation;lipid transport;apoptosis;signal transduction;lipid metabolic process;signal transduction;cellular

             tRNA aminoacylation for protein translation                aminoacyl-tRNA synthetase
                                                                        dehydratase;epimerase/racemase;deaminase
             neurological system process;synaptic transmission;gluconeogenesis;cellular amino acid biosynthetic process;cellular
             intracellular protein transport                            transfer/carrier protein
                                              SNARE complex
             intracellular protein transport;exocytosis                 SNARE protein
             intracellular protein transport;vesicle-mediated transport membrane traffic protein;phospholipase


            proteolysis                                                   serine protease inhibitor
            proteolysis                                                   serine protease inhibitor
            nuclear mRNA splicing, via spliceosome                        mRNA splicing factor
            nuclear mRNA splicing, via spliceosome
or;SGEF;ortholog
                                                                          signaling molecule
            intracellular signaling cascade;intracellular signaling cascade
            intracellular signaling cascade;intracellular signaling cascade
            neurological system process;proteolysis                       ubiquitin-protein ligase

                                                                        DNA repair;DNA recombination;establishment or maintenan
             regulation of transcription from RNA polymerase II promoter;DNA helicase;helicase
             protein amino acid glycosylation                           glycosyltransferase
             immune system process                                      type I cytokine receptor
             cell adhesion;cell adhesion                                G-protein modulator
                                                                        chemokine
             cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                        chromatin/chromatin-binding protein;deacetylase
             regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture;es
                                                                           transmembrane receptor regulatory/adaptor protein;signalin
             immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor p
                                                                           transmembrane receptor regulatory/adaptor protein;signalin
             immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor p
             cation transport                                              cation transporter
             transport                                                     mitochondrial carrier protein;transfer/carrier protein
                                             mitochondrial inner membrane;organelle
             carbohydrate transport;carbohydrate metabolic process         carbohydrate transporter
             ion transport                                                 transporter
             cation transport;extracellular transport                      cation transporter
             immune system process;cell cycle;cell cycle;cellular defense response
                                             extracellular matrix          receptor linked signal transduction
             cell surface receptor linked signal transduction;cell surface receptor;extracellular matrix protein
                                                                           transcription factor
             immune system process;transmembrane receptor protein serine/threonine kinase signaling pathway;intracellular signal
             protein folding                                               chaperone
                                                                           nucleic acid binding;G-protein modulator
             G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathwa

             intracellular protein transport                                kinase;kinase
             transcription initiation from RNA polymerase II promoter       transcription factor
                                                                            transporter;receptor
             lipid transport;intracellular protein transport;receptor-mediated endocytosis;lipid metabolic process
             regulation of transcription from RNA polymerase II promoterHMG box transcription factor;nucleic acid binding
             regulation of transcription from RNA polymerase II promoterHMG box transcription factor;nucleic acid binding
                                                                            transcription
             immune system process;transcription from RNA polymerase II promoter cofactor;zinc finger transcription factor;DNA bi
                                                                            transcription
             immune system process;transcription from RNA polymerase II promoter cofactor;zinc finger transcription factor;DNA bi
             spermatogenesis;cell motion microtubule                        microtubule family cytoskeletal protein


            nuclear mRNA splicing, via spliceosome
                                                                           amino acid biosynthetic process;cellular amino
            neurological system process;synaptic transmission;cellulardehydratase;epimerase/racemase;deaminase acid catabo
                                                                          protein
            phosphate metabolic process;protein amino acid phosphorylation kinase;protein kinase
                                                                          non-receptor amino acid phosphorylation;cytokinesis;mitos
            neurological system process;mitosis;calcium-mediated signaling;protein serine/threonine protein kinase;non-receptor se
STK11IP;ortholog
                                                                          transcription factor;nucleic RNA polymerase II promoter
            transcription initiation from RNA polymerase II promoter;regulation of transcription fromacid binding
            complement activation;response to stimulus                    complement component
                                                                          ATP synthase
            immune system process;cation transport;cellular defense response
            cation transport;vitamin transport;vitamin metabolic processcation transporter;transfer/carrier protein
                                                                          DNA binding protein;RNA binding protein;deaminase;kinase
            spermatogenesis;response to interferon-gamma;neurological system process;apoptosis;cell cycle;purine base metabo
                                                                          transcription factor
            immune system process;regulation of transcription from RNA polymerase II promoter;mesoderm development;hemopoi
                                                                          receptor linked
            cell surface receptor linked signal transduction;cell surface growth factor signal transduction
            RNA catabolic process                                         exoribonuclease;nuclease;esterase
                                                                          receptor
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                          transcription cofactor;zinc or maintenance of factor;nucleic
            regulation of transcription from RNA polymerase II promoter;proteolysis;establishment finger transcription chromatin arc
                                            mitochondrial inner membrane;organelle
                                                                          mitochondrial carrier protein;transfer/carrier protein
            intracellular protein transport;mitochondrial transport;mitochondrial transport
            sensory perception of sound;sensory perception;protein targeting
                                                                          cation transporter
            sensory perception of sound;sensory perception;cation transport;protein targeting;ectoderm development;nervous syste
            vitamin metabolic process;pentose-phosphate shunt             transketolase
                                                                          non-receptor serine/threonine protein kinase;non-receptor se
            mitosis;intracellular signaling cascade;DNA repair;DNA replication;protein amino acid phosphorylation;cytokinesis;mito
                                            extracellular matrix          receptor;extracellular matrix protein
            cytokine-mediated signaling pathway;cytokine-mediated signaling pathway

n 2;TMCC2;ortholog
                                                                             transduction;cell surface receptor linked signal transduction
             immune system process;cell surface receptor linked signal receptor
                                             actin cytoskeleton             actin family cytoskeletal protein;calmodulin
             muscle contraction;calcium-mediated signaling;calcium-mediated signaling;mesoderm development;muscle organ deve
                                             actin cytoskeleton             non-motor actin binding protein
             muscle contraction;mesoderm development;muscle organ development
             protein targeting;nuclear transport                            transporter;transfer/carrier protein
             regulation of transcription from RNA polymerase II promotertranscription cofactor;nucleic acid binding
             muscle contraction              actin cytoskeleton             actin binding motor protein
             protein folding                                                chaperone
                                                                            HMG box transcription factor;chromatin/chromatin-binding p
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin arc
                                                                              II promoter
             DNA repair;regulation of transcription from RNA polymerasetranscription cofactor;nucleic acid binding
                                                                            transcription factor
             induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;DNA repair;cell cycle
                                                                            signaling molecule
             immune system process;induction of apoptosis;cytokine-mediated signaling pathway;JNK cascade;I-kappaB kinase/NF
             intracellular protein transport
                                                                            ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteol
                                                                            transcription or maintenance of chromatin architecture;esta
             transcription from RNA polymerase II promoter;proteolysis;establishmentcofactor;nucleic acid binding;ubiquitin-protein l
                                                                            transcription or maintenance of chromatin architecture;esta
             transcription from RNA polymerase II promoter;proteolysis;establishmentcofactor;nucleic acid binding;ubiquitin-protein l
             proteolysis                                                    ubiquitin-protein ligase
                                                                            ion channel
             visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
             transport
             protein folding                                                chaperone

             protein metabolic process       microtubule                    ligase;microtubule family cytoskeletal protein
                                             tubulin complex;tubulin complextubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;
                                                                            non-receptor tyrosine protein kinase;non-receptor tyrosine p
             immune system process;apoptosis;apoptosis;protein amino acid phosphorylation;apoptosis;response to stress;cellular

            proteolysis;protein modification process                  ligase
            proteolysis;protein modification process                  transfer/carrier protein;ubiquitin-protein ligase
            mitosis;mitosis                                           membrane trafficking regulatory protein
                                                                      zinc finger transcription factor
            nucleobase, nucleoside, nucleotide and nucleic acid transport;cell cycle;nucleobase, nucleoside, nucleotide and nucle
UIMC1;ortholog
sequence does not appear to represent a valid product.

             proteolysis                                                 cysteine protease;cysteine protease
             proteolysis                                                 cysteine protease;cysteine protease
             proteolysis                                                 cysteine protease;cysteine protease
             gamete generation;proteolysis                               cysteine protease;cysteine protease
             proteolysis                                                 cysteine protease;cysteine protease
             proteolysis                                                 cysteine protease;cysteine protease
             proteolysis                                                 cysteine protease;cysteine protease
             gamete generation;proteolysis                               cysteine protease;cysteine protease
                                                                         homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;dorsal/ventral axis specification;ectoderm development;nerv
             lysosomal transport;intracellular protein transport
rotein 2A;VSTM2A;ortholog
                                                                         receptor;defense/immunity protein
             immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
mall GTPase regulator activity;guanyl-nucleotide exchange factor activityguanyl-nucleotide exchange factor
n 28 protein;WBSCR28;ortholog
             protein targeting;signal transduction;signal transduction   enzyme modulator

             transcription from RNA polymerase II promoter
                                                                           growth factor
             cell cycle;cell surface receptor linked signal transduction;cell-cell signaling;cell motion;cell cycle;cell surface receptor l
                                                                           signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                           signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
             JAK-STAT cascade;JAK-STAT cascade;mesoderm development
             proteolysis                                                   ubiquitin-protein ligase
             intracellular protein transport;vesicle-mediated transport
                                                                           nucleic acid binding

               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promotertranscription cofactor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterzinc finger transcription factor;DNA binding protein
or activity;transcription factor activity                                 KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
               regulation of transcription from RNA polymerase II promoterKRAB box transcription factor;nucleic acid binding

            regulation of transcription from RNA polymerase II promoterKRAB box transcription factor
 ;ZPLD1;ortholog
ZSWIM5;ortholog
             Pathway
             Blood coagulation->alpha-2-macroglobulin;;

sette (ABC) transporter
sette (ABC) transporter
sette (ABC) transporter



metalloprotease

ase;protein phosphatase

             Wnt signaling pathway->Transforming growth factor beta activated kinase 1;;TGF-beta signaling pathway->TGFbetarece
             TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;
metalloprotease
             Ornithine degradation->Ornithine decarboxylase;;
             Endothelin signaling pathway->3',5'-cyclic AMP synthetase;;GABA-B_receptor_II_signaling->Adenylate cyclase;;Hetero
             Wnt signaling pathway->NFAT Target Genes;;De novo purine biosynthesis->Adenylosuccinate synthase;;;

             Wnt signaling pathway->Transducin-like Enhance of Split 1-3;;




             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde deh




             Angiogenesis->Angiopoietin-2;;




ng;G-protein modulator


             EGF receptor signaling pathway->Epidermal growth factor;;
e;cysteine protease

e exchange factor
            Wnt signaling pathway->Switched/Sucrose Non Fermentation;;


             Wnt signaling pathway->Beta-Arrestin;;
/immunity protein;cell adhesion molecule




cleotide phosphatase;nucleotide phosphatase

ent;cellular defense response




king regulatory protein
             Apoptosis signaling pathway->Cellular inhibitor of apoptosis protein 1 and 2 ;;




             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
sette (ABC) transporter;carbohydrate transporter;ligase


g factor;nuclease




              Metabotropic glutamate receptor group III pathway->Calcium Channel;;5HT2 type receptor mediated signaling pathway-
              Huntington disease->Calpain;;
ptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis
intracellular signaling cascade;synaptic transmission;cell surface receptor linked signal transduction;intracellular signaling cascade


or;chromatin/chromatin-binding protein




             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;

  ctor;kinase activator
 /immunity protein;cell adhesion molecule
 eceptor superfamily;guanyl-nucleotide exchange factor;immunoglobulin receptor superfamily;cell adhesion molecule
d signaling molecule;cell adhesion molecule

             p53 pathway->Cell division cycle 25C;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ng;G-protein modulator




or;DNA-directed DNA polymerase;chromatin/chromatin-binding protein
            Nicotinic acetylcholine receptor signaling pathway->Nicotinic Acetylcholine Receptor;;Nicotinic acetylcholine receptor s



e;amino acid kinase



             Dopamine receptor mediated signaling pathway->chloride intracellular channel 6;;
king regulatory protein


             Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;
             Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;


or;nucleic acid binding
             Integrin signalling pathway->Collagen;;
             Integrin signalling pathway->Collagen;;

             Integrin signalling pathway->Collagen;;
             Integrin signalling pathway->Collagen;;
             Integrin signalling pathway->Collagen;;

binding protein
metalloprotease
metalloprotease



skeletal protein
              Angiogenesis->Crk oncogene;;Integrin signalling pathway->Crk;;;




           Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
otein;enzyme modulator
             Adrenaline and noradrenaline biosynthesis->Aromatic L-amino acid decarboxylase;;Dopamine receptor mediated signa




le;enzyme modulator
            Huntington disease->Postsynaptic density 95;;
eceptor regulatory/adaptor protein
eceptor regulatory/adaptor protein



e exchange factor
metalloprotease
 erine protease
             Axon guidance mediated by semaphorins->Collapsin response mediator protein;;Axon guidance mediated by semapho


               Oxidative stress response->MAP Kinase Phosphatases;;
               Oxidative stress response->MAP Kinase Phosphatases;;
 ription factor;DNA binding protein


or;nucleic acid binding
;acyltransferase;dehydrogenase;hydratase;ligase;epimerase/racemase



d signaling molecule
             Angiogenesis->Ephrin;;

              Angiotensin II-stimulated signaling through G proteins and beta-arrestin->early growth response;;
binding protein
on factor;isomerase



             PDGF signaling pathway->Ets;;

hatase;nucleotide phosphatase
inase receptor;tyrosine protein kinase receptor;protein kinase
            Angiogenesis->Ephrin Receptor;;
            Angiogenesis->Ephrin Receptor;;
protein;G-protein modulator
            Alzheimer disease-presenilin pathway->Ire-1;;Alzheimer disease-presenilin pathway->Ire-1 C-terminal fragment;;Alzheim


or;signaling molecule;nucleic acid binding

             Blood coagulation->Thrombin;;Blood coagulation->Prothrombin;;;
 e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin




eceptor superfamily;immunoglobulin receptor superfamily


             FGF signaling pathway->fibroblast growth factor;;

 inase receptor;tyrosine protein kinase receptor;protein kinase
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C




              Integrin signalling pathway->Filamin;;Dopamine receptor mediated signaling pathway->filamin A;;;
 ular matrix protein
              Nicotine degradation->Flavin-containing monooxygenase;;

             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->C
             Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor me



             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde deh



ubule binding protein
             PDGF signaling pathway->Ets;;
GABA receptor
             Glycolysis->Glyceraldehyde 3-phosphate dehydrogenase;;Huntington disease->Glyceraldehyde-3-phosphate dehydrog

 ription factor;nuclease
               TGF-beta signaling pathway->Transforming growth factor beta;;
               TGF-beta signaling pathway->Transforming growth factor beta;;
               TGF-beta signaling pathway->Transforming growth factor beta;;

             PI3 kinase pathway->Galpha;;Endothelin signaling pathway->guanine nucleotide binding protein q polypeptide;;Metabo
             Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->G protein, beta subunit;;Opioid proop

             N-acetylglucosamine metabolism->Glucosamine-6-phosphate deaminase;;




 eceptor regulatory/adaptor protein

             General transcription regulation->TFIIA;;Transcription regulation by bZIP transcription factor->TFIIA;;;
or;nucleic acid binding


helix transcription factor;non-motor actin binding protein


NA helicase;mRNA splicing factor;helicase;hydrolase
 oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;ex


 hatase;nucleotide phosphatase
 nding protein


atibility complex antigen
atibility complex antigen
              p53 pathway->High mobility group protein 1;;
              p53 pathway->High mobility group protein 1;;
              Wnt signaling pathway->Wnt Target Genes;;
metalloprotease



             p53 pathway->Insulin-like growth factor-binding protein 3;;

             Inflammation mediated by chemokine and cytokine signaling pathway->Interleukin 2;;




             Interleukin signaling pathway->Receptor subunit alpha;;
eceptor superfamily;immunoglobulin receptor superfamily
              De novo purine biosynthesis->IMP dehydrogenase;;
              Adrenaline and noradrenaline biosynthesis->Phenylethanolamine-N-methyltransferase;;Nicotine degradation->indolethy
tor linked signal transduction
eceptor superfamily;immunoglobulin receptor superfamily
              Interleukin signaling pathway->Insulin receptor substrate family;;Insulin/IGF pathway-protein kinase B signaling cascad


assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel




rix structural protein
cription factor


 ription factor;zinc finger transcription factor;nucleic acid binding




ng motor protein
ng motor protein

binding protein

;intermediate filament
;intermediate filament




              Integrin signalling pathway->Src;;Parkinson disease->Rous sarcoma protein tyrosine kinase;;T cell activation->Lck;;;;
otein;isomerase
              Cadherin signaling pathway->Transcription factor 4/Lymphoid enhancer-binding factor;;Alzheimer disease-presenilin pat
eceptor superfamily;immunoglobulin receptor superfamily
;actin family cytoskeletal protein
ein;cell adhesion molecule



binding protein
ular matrix glycoprotein
             Inflammation mediated by chemokine and cytokine signaling pathway->Interleukin 2;;Apoptosis signaling pathway->Tum
globulin superfamily cell adhesion molecule

             FGF signaling pathway->Mitogen-activated protein kinase kinase kinase;;
             S adenosyl methionine biosynthesis->S-Adenosyl methionine synthetase;;

             p53 pathway feedback loops 2->MDM-2;;p53 pathway->Mdm2;;Insulin/IGF pathway-protein kinase B signaling cascade

rix glycoprotein



skeletal protein;calmodulin

            Alzheimer disease-presenilin pathway->Afadin;;
            Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
ng motor protein
             Formyltetrahydroformate biosynthesis->Methylenetetrahydrofolate dehydrogenase;;
on factor;hydrolase


           Cholesterol biosynthesis->Mevalonate kinase;;
GTPase;microtubule family cytoskeletal protein
           Wnt signaling pathway->Wnt Target Genes;;




superfamily cell adhesion molecule
              Notch signaling pathway->Neuralized;;
              Wnt signaling pathway->NFAT;;B cell activation->NF-AT;;Inflammation mediated by chemokine and cytokine signaling
or;nucleic acid binding
binding protein



receptor;receptor;nucleic acid binding
receptor;receptor
oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;ex

hatase;nucleotide phosphatase




            Formyltetrahydroformate biosynthesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;Folate
erine protease

king regulatory protein




             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
             FAS signaling pathway->Poly(ADP-ribose) polymerase;;

helix transcription factor
 ription factor;DNA binding protein
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase
              Angiogenesis->Platelet-Derived Growth Factor Receptor;;
binding protein


              Opioid proenkephalin pathway->proenkephalin;;Opioid proenkephalin pathway->peptide E;;Opioid proenkephalin pathwa


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

 ;zinc finger transcription factor;chromatin/chromatin-binding protein




nnexin;calmodulin
cription factor




 inase receptor;signaling molecule;tyrosine protein kinase receptor;protein kinase

             p53 pathway->PML;;p53 pathway->Promyelocytic leukemia protein;;;
e;nucleotide phosphatase;nucleotide kinase;nucleotide phosphatase
erase;DNA-directed DNA polymerase
erase;DNA-directed RNA polymerase


 ription factor



              FGF signaling pathway->protein phosphatase 2A;;


              Wnt signaling pathway->Protein Kinase C;;B cell activation->PKC;;Thyrotropin-releasing hormone receptor signaling pa



              Hedgehog signaling pathway->Patched;;

             Integrin signalling pathway->Protein tyrosine phosphatase-PEST;;
ase;protein phosphatase
ase;protein phosphatase
phosphatase;protein phosphatase


              Huntington disease->Rab8;;PDGF signaling pathway->Ras;;;
 clease;nuclease;hydrolase



              Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->Ras;;Angiogenesis->Ras GTPase-



 erine protease



 ctor;ubiquitin-protein ligase




erase;phosphatase;phosphatase


nsporter;cation transporter
 ular matrix protein

              Beta2 adrenergic receptor signaling pathway->ER-type Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->E
ription factor;nucleic acid binding

 ription factor;nucleic acid binding




merase/racemase;deaminase


 protein;phospholipase




              Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein

              p53 pathway->Sirtuin;;
eceptor regulatory/adaptor protein;signaling molecule
            Interleukin signaling pathway->Src-like protein tyrosine kinase (PTK) family;;

rier protein;transfer/carrier protein


             Adrenaline and noradrenaline biosynthesis->amine translocator;;

 ular matrix protein
              TGF-beta signaling pathway->Inhibitory Smads;;TGF-beta signaling pathway->RSmads;;TGF-beta signaling pathway->

 ng;G-protein modulator




iption factor;nucleic acid binding
iption factor;nucleic acid binding
ctor;zinc finger transcription factor;DNA binding protein
ctor;zinc finger transcription factor;DNA binding protein
y cytoskeletal protein



merase/racemase;deaminase

             p53 pathway by glucose deprivation->Serine/threonine protein kinase 11;;

or;nucleic acid binding


r;transfer/carrier protein
ein;RNA binding protein;deaminase;kinase activator;defense/immunity protein

            TGF-beta signaling pathway->Transforming growth factor beta;;
nuclease;esterase

ctor;zinc finger transcription factor;nucleic acid binding;ubiquitin-protein ligase
rier protein;transfer/carrier protein



ne/threonine protein kinase;non-receptor serine/threonine protein kinase
             Toll receptor signaling pathway->Toll-like receptor 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12;;
skeletal protein;calmodulin
binding protein
 er/carrier protein
 ctor;nucleic acid binding


iption factor;chromatin/chromatin-binding protein
ctor;nucleic acid binding
              Huntington disease->P53 tumor suppressor phosphoprotein;;P53 pathway feedback loops 1->P53;;p53 pathway->p53;;
              Apoptosis signaling pathway->TNF receptor-associated factor 2;;p53 pathway->TRAF;;;


 ctor;nucleic acid binding;ubiquitin-protein ligase
 ctor;nucleic acid binding;ubiquitin-protein ligase

              Alzheimer disease-presenilin pathway->Capacitative calcium channels;;



e family cytoskeletal protein

sine protein kinase;non-receptor tyrosine protein kinase


             Parkinson disease->Ubiquitin-conjugating enzyme 6;;
king regulatory protein




e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
e;cysteine protease
ription factor;DNA binding protein


/immunity protein
e exchange factor
              Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathw
              Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Angiogenesis->Wingless-Type MM

              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;



cription factor

cription factor
cription factor
cription factor;nucleic acid binding
cription factor
 ription factor;DNA binding protein
cription factor
cription factor
cription factor
cription factor;nucleic acid binding

cription factor
 ling pathway->TGFbetareceptor I;;TGF-beta signaling pathway->TGFbetareceptors;;;;
ceptors;;;


 >Adenylate cyclase;;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->Adenylyl cyclase;;;;
ate synthase;;;




n->Phenylacetaldehyde dehydrogenase;;;
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
mediated signaling pathway->Ca2+ channel;;Thyrotropin-releasing hormone receptor signaling pathway->Ca2+ channel;;Metabotropic


 acellular signaling cascade;synaptic transmission




 n molecule
nic acetylcholine receptor signaling pathway->Acetylcholine receptor protein, beta;;;




ted ion channel;;
ted ion channel;;
ne receptor mediated signaling pathway->Aromatic L-amino acid decarboxylase;;Histamine synthesis->Histidine Decarboxylase;;5-H




ance mediated by semaphorins->CRMP 3-associated molecule;;Pyrimidine Metabolism->Dihydropyrimidinase;;;;




nse;;




C-terminal fragment;;Alzheimer disease-presenilin pathway->Ire-1 N-terminal fragment;;;;
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3




n A;;;



-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
-beta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3
e 1;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signalin



n->Phenylacetaldehyde dehydrogenase;;;
yde-3-phosphate dehydrogenase;;;




 tein q polypeptide;;Metabotropic glutamate receptor group I pathway->Gq;;Thyrotropin-releasing hormone receptor signaling pathwa
, beta subunit;;Opioid proopiomelanocortin pathway->G-protein;;5HT1 type receptor mediated signaling pathway->G-protein;;5HT4 ty




>TFIIA;;;




protease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule
tine degradation->indolethylamine N-methyltransferase;;;


kinase B signaling cascade->Insulin receptor substrate family;;PI3 kinase pathway->Insulin Receptor Substrate;;Insulin/IGF pathwa




;;T cell activation->Lck;;;;

imer disease-presenilin pathway->T-cell factor/lymphoid enhancer factor;;Wnt signaling pathway->T cell factor;;;;
osis signaling pathway->Tumor necrosis factor;;;




kinase B signaling cascade->Mdm2;;P53 pathway feedback loops 1->Mdm2;;p53 pathway->Mouse double minute 2;;Insulin/IGF pa
 ine and cytokine signaling pathway->Nuclear factor of activated T cells;;T cell activation->NF-AT;;;;;




protease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule




drofolate reductase;;Folate biosynthesis->Dihydrofolate synthase;;;;
Opioid proenkephalin pathway->Enkephalin;;Enkephalin release->preproenkephalin mRNA;;Opioid proenkephalin pathway->met-Enke




 mone receptor signaling pathway->PKC;;Inflammation mediated by chemokine and cytokine signaling pathway->Protein kinase C;;A
ngiogenesis->Ras GTPase-Activating Protein;;Angiogenesis->GTPase-Activating Protein;;Interleukin signaling pathway->Ras GTPa




eptor signaling pathway->ER-type Ca2+ channel;;;




1 GTPase-activating protein 1;;
F-beta signaling pathway->I-SMAD;;;;
->P53;;p53 pathway->p53;;p53 pathway by glucose deprivation->p53;;p53 pathway feedback loops 2->p53;;P53 pathway feedback l
er disease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family membe
nesis->Wingless-Type MMTV Integration Site Family;;Alzheimer disease-presenilin pathway->Wingless-type protein;;Wnt signaling
ay->Adenylyl cyclase;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
Ca2+ channel;;Metabotropic glutamate receptor group II pathway->Calcium Channel;;Beta1 adrenergic receptor signaling pathway->C
istidine Decarboxylase;;5-Hydroxytryptamine biosynthesis->Aromatic L-amino acid decarboxylase;;;;;




nase;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;




bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
bdomyosarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
e receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;
e receptor signaling pathway->G-Protein;;Alpha adrenergic receptor signaling pathway->G-Protein;;Muscarinic acetylcholine recepto
athway->G-protein;;5HT4 type receptor mediated signaling pathway->G-protein;;Endogenous_cannabinoid_signaling->Gbeta;;Inflamm
bstrate;;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->Insulin receptor substrate family;;;;;




factor;;;;
le minute 2;;Insulin/IGF pathway-protein kinase B signaling cascade->Mdm2;;p53 pathway feedback loops 2->MDM-2;;P53 pathwa
ephalin pathway->met-Enkephalin;;Enkephalin release->preproenkephalin;;Opioid proenkephalin pathway->peptide F;;Opioid proenk




athway->Protein kinase C;;Alzheimer disease-amyloid secretase pathway->Protein kinase C;;EGF receptor signaling pathway->PKC
aling pathway->Ras GTPase Activity Protein;;PDGF signaling pathway->Ras GTPase Activity Protein;;FGF signaling pathway->p12
53;;P53 pathway feedback loops 1->Tumor protein p73;;p53 pathway->p53;;;;;;;;
egration site family member;;;;
type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;;
ceptor signaling pathway->Ca2+ channel;;Alzheimer disease-amyloid secretase pathway->L-type calcium channels;;Oxytocin recep
arinic acetylcholine receptor 1 and 3 signaling pathway->Gq;;Wnt signaling pathway->Galpha;;Oxytocin receptor mediated signaling
d_signaling->Gbeta;;Inflammation mediated by chemokine and cytokine signaling pathway->G beta/gamma subunits;;Thyrotropin-re
ptor substrate family;;;;;
ps 2->MDM-2;;P53 pathway feedback loops 1->Mouse double minute 2;;;;;;;;;
->peptide F;;Opioid proenkephalin pathway->leu-Enkephalin;;Enkephalin release->Enkephalin;;;;;;;;;;




or signaling pathway->PKC;;Histamine H1 receptor mediated signaling pathway->PKC;;Muscarinic acetylcholine receptor 1 and 3 s
GF signaling pathway->p120 Ras GTPase-activating protein;;EGF receptor signaling pathway->GAP;;;;;;;;
m channels;;Oxytocin receptor mediated signaling pathway->Ca2+ channel;;Nicotinic acetylcholine receptor signaling pathway->Calc
eceptor mediated signaling pathway->G-Protein;;5HT2 type receptor mediated signaling pathway->G-protein;;Histamine H1 receptor
ma subunits;;Thyrotropin-releasing hormone receptor signaling pathway->G-Protein;;Beta3 adrenergic receptor signaling pathway->G
ylcholine receptor 1 and 3 signaling pathway->Protein kinase C;;VEGF signaling pathway->Protein Kinase C;;Angiogenesis->Protein
;
or signaling pathway->Calcium Channel;;Beta2 adrenergic receptor signaling pathway->Ca2+ channel;;;;;;;;;;
ein;;Histamine H1 receptor mediated signaling pathway->G-Protein;;Cortocotropin releasing factor receptor signaling pathway->G-P
eptor signaling pathway->G-Protein;;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->G protei
e C;;Angiogenesis->Protein Kinase C;;Oxytocin receptor mediated signaling pathway->PKC;;FGF signaling pathway->PKC;;Endoth
;;;;;;
or signaling pathway->G-Protein;;Inflammation mediated by chemokine and cytokine signaling pathway->Gi/q alpha subunits;;Inflam
ediated pathway->G protein, beta subunit;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->G
ing pathway->PKC;;Endothelin signaling pathway->protein kinase c;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go al
>Gi/q alpha subunits;;Inflammation mediated by chemokine and cytokine signaling pathway->Gq alpha subunit;;;;;;;;;;;;;;
alpha mediated pathway->G protein-activated inward rectifying potassium channel;;Angiotensin II-stimulated signaling through G pro
athway-Gq alpha and Go alpha mediated pathway->Protein kinase C;;Metabotropic glutamate receptor group I pathway->Protein kin
ubunit;;;;;;;;;;;;;;
 ed signaling through G proteins and beta-arrestin->G-protein, beta subunit;;Muscarinic acetylcholine receptor 1 and 3 signaling path
oup I pathway->Protein kinase C;;5HT2 type receptor mediated signaling pathway->PKC;;Apoptosis signaling pathway->Protein kin
eptor 1 and 3 signaling pathway->Gq;;Histamine H2 receptor mediated signaling pathway->G-Protein;;Opioid proenkephalin pathway
aling pathway->Protein kinase C;;;;;;;;;;;;;;;;;;
ioid proenkephalin pathway->G-protein;;Metabotropic glutamate receptor group III pathway->Gi;;PI3 kinase pathway->Gbetagamma;
e pathway->Gbetagamma;;Enkephalin release->G-Protein (s);;Metabotropic glutamate receptor group II pathway->G-protein;;Opioid
pathway->G-protein;;Opioid prodynorphin pathway->G-protein;;Muscarinic acetylcholine receptor 2 and 4 signaling pathway->Gi;;Ox
signaling pathway->Gi;;Oxytocin receptor mediated signaling pathway->G-Protein;;Enkephalin release->G-Protein (i);;GABA-B_rece
G-Protein (i);;GABA-B_receptor_II_signaling->Gbeta;;Beta1 adrenergic receptor signaling pathway->G-Protein;;Heterotrimeric G-pro
otein;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->G protein beta subunit;;Histamine H1
beta subunit;;Histamine H1 receptor mediated signaling pathway->G-Protein;;5HT2 type receptor mediated signaling pathway->G-pro
d signaling pathway->G-protein;;Beta2 adrenergic receptor signaling pathway->G-Protein;;Cortocotropin releasing factor receptor sig
eleasing factor receptor signaling pathway->G-Protein;;Wnt signaling pathway->G_Beta;;Dopamine receptor mediated signaling pat
ptor mediated signaling pathway->G protein, beta subunit;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;

				
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