Delphinol Clinically Proven in the Mainenance of Glucose Balance
Researchers at the Universidad Austral De Chile discovered that Delphinol, a standardized extract
of maqui Berries can control sugar absorption by a novel mechanism of action.
Bradenton, FL, May 24, 2013 --(PR.com)-- Overeating and lack of physical exercise is turning into a
global pandemia with metabolic syndrome as a hallmark and type II diabetes representing the fastest
growing disease. The present lifestyle makes it difficult to turn to healthier lifestyles that include
improved dietary control and regular physical activity. In this context, polyphenols from berries, fruits
and vegetables have shown at large to contribute to a healthier blood sugar control and maintain body
weight within normal limits. Typically the plant polyphenols slow-down absorption of dietary starch,
releasing the glucose less rapidly into the blood stream by impairing the activity of digestive enzymes,
such as alpha-amylase and alpha glucosidase.
Most recently, researchers at the Universidad Austral de Chile discovered that Delphinol®, a
standardized extract of Maqui berries (NLT 25% delphinidins) indigenous to Chile, can control sugar
adsorption by a novel mechanism of action. The researchers found that the isolates and extract prepared
from wild-growing Maqui berries, inhibited Na+-dependent glucose transport (SGLT-1) and stimulated
incretin secretion. The regulation of SGLT-1 involves a postprandial mechanism, followed by a
recruitment of glucose transporter GLUT-2, which depends on the levels of sugars in the intestinal lumen.
Interestingly, the activity of SGLT-1 and GLUT-2 is increased in type II diabetes.
Besides, in a phase I pilot study, Delphinol® was able to decrease the postprandial glucose and plasma
insulin in patients with impaired glucose tolerance, modifying the shape of the curves for insulin and
glucose, suggesting its potential use for prediabetic patients and as well in diseases associated to impaired
carbohydrate metabolism. Volunteers were assigned to one of two groups, either receiving 200 mg
Delphinol® or placebo. Thirty minutes later, 75 grams rice was given and the post-prandial blood glucose
and insulin were monitored. While the placebo-treated group presented the typical rapid rise of glucose
and insulin, the group given Delphinol® had only marginally increasing blood glucose and insulin levels
over a period of one hour. After 90 minutes glucose and insulin rose to limited extent to then finally drop
to baseline levels again. The results of this study present encouraging news for people who need to
control their blood sugar and insulin levels. Delphinol®, exclusively available from Maqui New Life, is a
safe and totally natural dietary supplement, under continuous research for identifying health benefits to
HP Ingredients is the Exclusive North American Distributor of Delphinol.
About HP Ingredients
HP Ingredients is a fast growing innovative nutraceutical company focused on bringing science based and
patented natural remedies to the nutraceutical industry. HP Ingredients is dedicated to providing science
based natural health solutions that are effective in supporting the most common chronic conditions
affecting our lifestyle. Heart disease, diabetes, obesity, low testosterone and low energy are conditions
that have become far too common. We work closely with a team of scientists from around the world to
bring you LJ100® Standardized Eurycoma Longifolia Extract (22% Bioactive Eurypeptides) for men's
health and sport nutrition; ParActin® - the first PPAR agonist to the market, effective for brain health,
joint health, and minor pain management; Bergamonte®, a science based nutraceutical for metabolic
syndrome, cholesterol & blood glucose control, and weight management; and Maqui SuperberryTM the
highest antioxidant superfruit. Most of our scientists have been awarded several worldwide patents for
their innovative works.
Jara E et al. Studies of standardized extract of Maqui fruit rich in Delphinidins (Delphinol®) in the
maintenance of glucose balance. Submitted 2013
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