AimHow can we design an experiment to test our coaster cars by yaofenjin

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									            Aim: What inherited disease will you
                        research?
   802 Agenda for Friday, February 2nd
   Do Now: Science News
    – Read the article about blue eyes on the blog and post and 2-
      3 sentence response
    – Take out HW, I will call you up to grade it.
   HW Review- 3-10/ Questions from Sickle Cell Video
   Mini Lesson:
    – Inherited Disorders/ Video on Tay-Sachs
   Practice with Pedigrees/ Unit 3 Review
   Class Research:
           Go to japplebaum@edublogs.org and choose one of the
            inherited diseases to research, work with a partner to create a
            PowerPoint presentation on the disease of your choice.
   Homework: Read the Sleep Gene Article and write a
    summary
Video Questions- Sickle Cell
 How can a mutation be harmful in one
  environment and helpful in another?
 Why should a mutation persist if it kills
  people?
 Why are there more people with sickle
  cell disease in one part of the world
  than in other parts?
Video Questions- Tay Sachs
 How can a mutation in a single DNA
  base affect the production of normal
  proteins?
 How are mutations passed on to
  offspring?
 What does it mean to be a carrier of a
  disease?
 What is the pattern of inheritance for
  diseases carried by recessive genes?
 What is Tay Sachs?
       Project Description
 Make a Power Point presentation on one of
  the genetic disorders listed on the blog
 Be sure to include the following
  information:
 What is the disease? What causes it? What
  are the symptoms? Can it be treated?
 Include pictures, diagrams, and resources
     Aim: What types of disorders and diseases
                 can be inherited?
   802 Agenda for Wednesday, January 30th
   Do Now: Quick Review
    – In your own words, explain why the gender of a
      baby is determined by the father.
    – Take out HW, I will come around to grade it
   HW Review- 3-8 and 3-9 or paragraph
   Mini Lesson:
    – Inherited Disorders/ Video on Sickle Cell Anemia
   Class Research:
          Go to japplebaum@edublogs.org and choose one of the
           inherited diseases to research, post your research notes.
           Include your source.
   Homework: Reading (3-10)
               Homework Review
   3.8                          3.9
   1. the 23rd pair             1. traits that are inherited along
                                  with the gender (on 23rd pair)
   2. women are xx and can
    only donate an x             2. because she has inherited
                                  another normal allele that masks
   3.The father                  the disorder
   Checking Concepts            3. because they can only inherit
   1. 23rd pair                  one allele, if it is for a disease they
   2. x chromosomes              will automatically show signs of the
   3. sperm                      disorder
   4. female                    4. because he would actually have
                                  hemophilia, not just carry it
   5. male
                                 5. to show how traits are passed
                                  through a family
                                 Checking Concepts
                                 1. sex-linked
                                 2. X
                                 3. recessive
                                 4. carrier
                                 5. will
         Inherited Disorders
   Most inherited disorders or diseases are the
    result of a mutation
   A mutation is a change in the genetic material
   Mutations can occur be the result of a change to
    just one letter in the DNA code or whole missing
    piece of a chromosome
   Some inherited disorders are recessive while a
    few are dominant
   If the inherited disorder is a recessive, a person
    can be a carrier for a disease without having any
    of the symptoms of the disease
Types Of Mutation: Chromosomal
        versus base pair
   Base pair occur in the
    actual nitrogen bases of
    the DNA
   Chromosomal include a
    missing or extra
    chromosome, or when a
    piece of a chromosome is
    missing or added.
    Chromosomal are often so
    severe that they result in
    miscarriage of the affected
    fetus
When a the allele for a disorder is dominant it makes
                  a huge difference.
Sickle Cell Anemia is recessive (s) while Huntington’s
      Disease is coded for by a Dominant allele.


           S    s                   H        h

  S      SS         Ss        h      Hh      hh

 s        Ss        ss                           hh
                             h          Hh
Pedigree Charts
       Video Questions
 How can a mutation be harmful in one
  environment and helpful in another?
 Why should a mutation persist if it kills
  people?
 Why are there more people with sickle
  cell disease in one part of the world
  than in other parts?
    Aim: How do your chromosomes determine
                 your gender?
   802 Agenda for Tuesday, January 29th
   Do Now:
    – Generate 3 questions per table that you have
      about genetics. Write on the post-it provided and
      post to question wall.
    – Take out HW
   HW Review- 3-7
   Video Lesson:
    – Gender Determination, Blood Types
   In Class Practice Problems:
          Incomplete Dominance/ CoDominance/ Blood Type
   Homework: Reading (3-8, 3-9)
                        3-7
   1. the phenotypes blend together because neither allele
    is completely dominant
   2. In incomplete dominance the alleles are blended, but
    in codominance both alleles appear side by side
   3. none of the genes are dominant, example of
    codominance
   4.BW x BW= BB, BW, WW
   1. Pink flowers: RW
   2. RR x WW= 100% pink, RW
   3. WW- white feathers
   4. BW will give you black and white feathers
   5. BW x BW= 25% BB, 50% BW, 25% WW
    Blood Type

    A       O

B   AB      B

O       A   OO
       Aim: What is the difference between
    Incomplete Dominance and Co-Dominance?
   802 Agenda for Monday, January 28th
   Do Now: Practice 8th Grade Science Test
    Problems
    – Clear off your desk, as if you were about to take a
      quiz and complete the handout (No talking!)
   HW Review- Practice Punnett Square
    Problems
   Mini-Lesson: Incomplete and Co-Dominance
   Blog-Baby Swaps, Crime Scenes & DNA tests
          go to japplebaum.edublogs.org and read and post
   Homework: KWL, Reading (3-7)
Rabbit 1- is heterozygous Black
      Rabbit 2- is Brown

          B        b

    b     Bb           bb

   b          Bb       bb
 Results of a Pea Plant homozygous for purple
   (PP) and a homozygous white plant (pp):
F1 generation: 100% heterozygous purple (Pp)

                 P        P

           p     Pp           Pp

           p         Pp       Pp
Results of a a cross between any two F1 generation plants
                         (Pp X Pp)
 F2 generation: 50% heterozygous purple (Pp), 25%
  homozygous purple (PP), 25% homozygous white
            (pp), (75% Purple,25% white)


                     P        p

               P      PP          Pp

              p          Pp       pp
       Test Cross 1: Unknown Guinea Pig has a
             homozygous black coat (BB)
       Test Cross 2: Unknown Guinea Pig has a
             heterozygous black coat (Bb)
BOTH ARE CROSSED WITH A HOMOZYGOUS BROWN (BB)


         B   B                B        b

b     Bb      Bb         b     Bb          bb

b       Bb       Bb                        bb
                        b         Bb
 Incomplete
 Dominance
In incomplete
dominance both of
the alleles are
expressed, so when
an organism is
heterozygous the
result is a blended
phenotype.
Ex: Red + White =
Pink
CoDominance
In co-dominance
both alleles are
expressed fully. The
phenotype is NOT a
blend.
Ex: If you mate a
Brown roan cattle
with white cattle,
you will get a
speckled brown and
white cow
Pea Plant 1 is Tt, Plant 2 is tt


              T    t

        t     Tt   tt

        t    Tt    tt
                Hypothesis
   There are 2 great models:
   If, then, because
    – If (describe the independent variable here) then the
      (dependent variable) will because (provide a reason).
    – If the mother alien has homozygous squiggly and the
      father has straight antennas then all of the baby
      aliens will have heterozygous squiggly antennas
      because the Punnett Square shows that each will get
      one recessive and one dominant gene.
   IV impacts DV because
    – (The independent variable) will affect (the dependent
      variable) by (describe how) because (explain why).
              Hypothesis
 In order to write a good hypothesis, you must
    be able to identify the independent and
    dependent variables
          Independent variable- the factor changed
          Dependent variable- the factor being observed or measured
   There are 2 great models:
   If, then, because
    – If (describe the independent variable here) then the
      (dependent variable) will because (provide a reason).
   IV impacts DV because
    – (The independent variable) will affect (the dependent
      variable) by (describe how) because (explain why).

								
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