Phys of Osseous Tissue

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					Phys of Osseous Tissue
   Mineral Deposition: crystallization of Ca2+, P
    and other ions to form bone
   Mineral resorption: dissolving of bone caused
    by an enzyme acid phosphates that is
    produced by osteoclasts
   Ca2+ is used in many body processes and must
    be regulated to maintain normal body function
Phys of Osseous Tissue
   Bones act as a storage center for key minerals
    Ca2+ being one of most important
   Bones have two Ca2+ reserves: 1) stable part
    of bone hard to release into blood, 2) about
    1% of bone mass that is released or absorbed
    with need
   Hypocalcemia: low blood Ca2+ leads to
    tremors and spasms
Phys of Osseous Tissue
   Hypercalcemia: high levels of Ca2+ in blood
    leads to muscle weakness, emotional
    disturbances, Code Blue
   Calcitriol: is a form of Vit D that acts as a
    hormone to raise Ca2+ absorption in SI and
    increase resorption
   Calcitonin: is produced by the thyroid gland
    to inhibit resorption and promote deposition
Phys of Osseous Tissue
   Parathyroid Hormone (PTH): produced by the
    parathyroid to increase the resorption
   Draw up a negative feedback loop for Ca2+
    levels in the blood include the three acting
    hormones, hypo and hypercalcemia and
    resorption and deposition

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