Operation 1 and 2 in Hospital Radio-pharmacy competency based training

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					IAEA Training Course: “Certificate in Recent Advances in Hospital Radiopharmacy ”
Venue: Department of Nuclear Mediciene, St Luke’s Medical Center, Quezon City, Philippines IAEA experts: I: K.Solanki A: Dr Yu Date of the Course: September 24 – 28, 2007

Morning 8:0012:30

Monday, Sept 24 Opening Ceremonies Pre-Test Lect. 1- General introduction to RP* course. IAEA guide in hospital radiopharmacy and GMP In hospitals- I 8:00-10:00 Lect. 2 Production of radionuclides. Radioactive component of RP. Characteristics and the selection of radionuclides RP. Properties of generator systems Tc/Mo generators: wet and dry generators. Generator profile - A 10:15-11:45 Lect. 3 Basic operations (Basic aspects, staff, design of facilities). Centralized radiopharmacy I 11:45-12:30 Practical:-A Different generator experiments: Profile elution records build up. Al-breakthrough. Practical: I Look at RP mathematics in practice. Mathematics in daily RP practice. Radioactive decay calculation of common RP. Generator calculation from reference dose and volume.

Tuesday, Sept 25 Lect.1 Radiopharmacology and mechanism.-Basic principles. -Overview of different radiopharmaceutials used in NM. A 8:00-10:00

Wednesday, Sept 26 Lect.1- PET radiopharmaceuticals Safe handling of PET products. Dose calculation of FDG. Dispensing dose A 8:00-10:00

Break 10:0010:15

Lect 2. Aseptic assessment Basic environmental monitoring Broth run (Part 1). Microbiology in practice. I 10:15-11:30 Lect. 3 QA in Hospital RP QC in Hospital RP Radionuclide purity Radiochemical purity Chromatography, pH Particles Temperature Shelf life Practical: A 11:30-12:30

Thursday, Sept 27 Lect. 1RP results Routine monitoring and trouble shooting in RP. QA in hospital RP and QC radiopharmaceuticals PET validation and parametric release. I 8:00-9:00 Lect. 2 . Infection imaging. A 9:00-9:45 Lect.3 Radiolabelling of white cells. I Practical: A Radiolabelling of white blood cells 10:00-11:30 Practical: I Competencies of staff working in RP. Staff induction in RP practices Creating competencies list. Practical accreditation. Creating site file. QA policy; Working SOPs Site Visitation & Field Demonstration (in coordination with commercial RP companies)

Friday, Sept 28 Lect.1- Safe handling of radioiodine. Fume hoods and safety cabinets. Radioactive packages (Categories, ordering, receiving, sending radioactive substances) Radioactive waste related to RP and safe practices. A 8:00-10:00

Lect. 2. Working a RP monograph- FDG. Factors for parametric release I 10:15-11:15

Lect. 2- RP licensing systems and role of pharmacopoeia. Working a RP monograph I

Lunch 12:301:30

Lect. 3 Aseptic assessment Basic environmental monitoring Broth run (Part 2). Microbiology in practice. I 11:15-12:30

Afternoo n 2:00-4:30

Practical: A QC Run chromatography pH Keeping quality log sheets Documentation- worksheet IT, RP database, and electronic work sheet.

Practical: I Create ideal layout and state why. Microbiology in practice: Aseptic practice – a) Generator b) Kit preparation Practical: A Dispensing practices -VLFC -Isolator Look at package insert of different RP kits and establish working parameters.

Lect. 3-Monoclonal and Peptides in RP Practical: Dispensing Monoclonal antibody or peptide RP. -Handling beta emitters and types of radiation monitors Radiation hygiene Standardization of calibrator and geometry A Post Test Interactions and Discussions A, I, TSL - Cover area of RP training specific to trainee request. - Assess training - Continuous development. - Journal reading and online support. Practical log-book keeping for at least 3 months. Trainee and tutor support. Method of final assessment and certification. Closing Ceremonies


				
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