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					          FP6 Thematic Priority 1:
Life Sciences, Genomics, and Biotechnology
                 for Health

             Dr. Neil T. M. Hamilton
               Executive Director
                Synopsis

• Areas of focus in this Thematic Priority
• What’s left in FP6
• Why you should be involved
• How to get involved


• http://www.cordis.lu/fp6/lifescihealth.htm
      6th Framework Programme
•   1.1.1 Life sciences, genomics and biotechnology
•        for health                                       2255
•   1.1.2. Information society technologies               3625
•   1.1.3. Nanotechnologies and nano-sciences, knowledge-
•        based multifunctional materials & processes      1300
•   1.1.4. Aeronautics and space                          1075
•   1.1.5. Food quality and safety                         685
•   1.1.6. Sustainable development, global change
•        and ecosystems                                   2120
•   1.1.7. Citizens and governance in a
•        knowledge-based society                           225

• Budget: 3984 Billion Euros……..
                     Thematic Priority 1:
       Life Sciences, Genomics and Biotechnology for
                          Health
1.1 Advanced genomics and its application
    for health                                                 (€ 1100 M)
       1.1.a     Fundamental knowledge and basic tools for
                 functional genomics in all organisms
       1.1.b      Applications of knowledge and technologies
               in        the field of genomics and
               biotechnology for health

 1.2    Combating major diseases                               (€ 1155 M)
        1.2.a     Application oriented genomic approaches to
                  medical knowledge and technologies            755 M
        1.2.b     Combating cancer
        1.2.c     Confronting the major communicable            400 M
                  diseases linked to poverty
1.1.a. Fundamental knowledge and basic tools for
       functional genomics in all organisms

                   Gene expression and proteomics


                   Structural genomics


                   Comparative genomics and population genetics

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                   Bioinformatics
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                   Multidisciplinary functional genomics approaches
                   to basic biological processes
1.1.b. Applications of knowledge and technologies
     in genomics and biotechnology for health
     Development of new, safer and more effective drugs including
     pharmacogenomics approaches

     Development of new diagnostics

     Development of      new   in-vitro   tests   to   replace   animal
     experimentation

     Development and testing of new preventive and therapeutic tools,
     such as somatic gene and cell therapies (in particular stem cell
     therapies, for example those on neurological and neuromuscular
     disorders) and immunotherapies

     Innovative research in post-genomics, which has high potential
     for application
               Thematic Priority 1:
 Life Sciences, Genomics and Biotechnology for
                    Health


        Combating major diseases


               (1155 M € )



   Medical                   Poverty-
knowledge &     Cancer        related
technologies                 diseases
1.2. Aplication-oriented genomic approaches to medical knowledge
                                                and technologies




           Combating cardiovascular diseases, diabetes, and
           rare diseases


           Combating resistance to antibiotics and other drugs


           Studying the brain and combating diseases of the
           nervous system


           Studying human development and the ageing
           process
                1.2.b. Combating cancer

A BROADER APPROACH: The focus not limited to genomics and basic
                          research



                  Patient-oriented strategies from
                  prevention to diagnosis and treatment
                   – establishing facilities for the exploitation of research
                     on cancer in Europe; development of evidence based
                     guidelines for good clinical practice and improved
                     public health strategies
                   – supporting translational research aimed at bringing
                     basic knowledge through to applications in clinical
                     practice and public health
                   – supporting clinical research (clinical trials)
1.2.c. Confronting the major communicable diseases
                  linked to poverty
 A BROADER APPROACH: The focus not limited to genomics and basic
                          research


• AIDS, malaria and tuberculosis
   – Developing promising candidate interventions (vaccines, therapies
     and HIV microbiocides) - molecular research, pre-clinical testing and
     proof of principle

   – Establishing a clinical trial programme for these diseases to improve
     coherence and complementarity - special target = interventions for use
     in developing countries


   – Establishing an AIDS Therapy Trials Network in Europe.
               A Pioneer New Instrument on
         Structural Genomics: SPINE
Structural Proteomics in Europe


Objective: to develop high throughput
technologies to solve 300-500 protein
structures relevant to human health

From production to structure analysis

Duration: 3-year programme

Participants: 20 partners from 7 countries

EU contribution: 13.7 million €

www.spineurope.org
                A Pioneer New Instrument on
                  Mouse Phenotyping:

European Union Mouse Genetics
Research for Public Health and
Industrial Applications


Objective: standardising and testing
phenotyping protocols in mice

Duration: 3-year programme

Participants: 17 partners from 8 countries

EU contribution: 12.3 million €

www.eumorphia.org
                 A Pioneer New Instrument on
                   Population genetics:

Genome-wide analyses of European twin
and population cohorts to identify genes
predisposing to common diseases


Objective: To harness the unique features of twin
cohorts for large scale studies of environmental &
genetic factors underlying complex diseases

Duration: 4-year programme

Participants: Originally 10 partners from 7
countries, now 13 partners from 9 countries

EU contribution: 13.7 million €

http://www.genomeutwin.org/
          What is left in FP6 ?
•   555 million Euros in IST research funding;
•   2005 / 06 Work Programme;
•   4th (and Final) Call for Proposals;
•    9th November deadline
•   Significant opportunities for international
    collaboration / co-operation
     4th Call Work Programme

• Final Call for Proposals in FP6
• 9th November deadline
• 555 million Euros
• Many but very specific areas: read the
  Work Programme!
      4th Call Work Programme
• Specific Support Action:
• LSH-2005-3-2: Stimulating international co-
  operation: Promotion and facilitation of international co-
  operation in areas relevant to the objectives of this
  priority. Particular emphasis will be on activities involving
  countries having S&T co-operation agreements with the
  EU. Actions should aim at networking scientists for
  stimulating the creation of research consortia and the
  identification of priorities of common interest in areas
  supported by the Theme.
          Why get involved?
• The Research World is changing
• Europe is (trying to) take on the USA
• Australia has acknowledged strengths
• Students, funding, engagement…..
• You need to think about, and prepare for,
  participation in future: FP7
     The European Research
            System
• Total research spend is 1.8% of GDP
• “European” and intergovernmental
  investment in R&D: 17% of total
• European Commission (FPs) investment is
  on 5% of total
• Member state investment DOMINATES
           FP6 Instruments
• Specific Targeted Research Projects
  – Support research & demonstration activities
  – 3+ participants
  – 300k – 4 million Euros, usually 50% of costs
• Integrated Projects
  – objective-driven research to generate new
    knowledge
  – 5 – 25 participants, with SMEs
  – 2 million – 20 million Euros, 50%+ of costs
       FP6 Instruments (cont)
• Networks of Excellence
  – Joint Programme of Activities:
  – Integrating activities: sharing facilities, IP, planning
  – Jointly executed research
  – Activities for spreading excellence: training,
    communication, innovation, networking
  – Management
  – 15-50 participants
  – 3 million – 30 million Euros, up to 100% of costs
       FP6 Instruments (cont)
• Specific Support Actions
  – Support implementation of FP, prepare for future
    Community research
  – 1+ participant
  – 100k – 3 million Euros, 100% of costs
• Co-ordination Actions
  – Promote and support networking, joint initiatives,
    training, exchange, expert groups
  – 1+ participants
  – 100k – 3 million Euros, 100% of costs
             How to get Involved

• 4th Call
• Very specific topics: read the Work Programme
• Join a consortium, talk to colleagues, NCPs
• Specific Support Actions: all areas
   – “Actions should aim at networking scientists for
     stimulating the creation of research consortia, and the
     identification of priorities of common interest”
Australian support for Collaboration
• NH&MRC European Union Health
  Research Collaboration Fund
• International Science Linkages (DEST)
• ARC
• Academies
• European embassies
• Many other opportunities
• Remember: we already spend ~$50 million!
7th Framework Programme
                  Six Major Objectives

                                       w
                    Technology       ne
                     initiatives
                                                               w
                                                             ne
   Excellence                           Basic research
    through                          through competition
  collaboration
                     6 axes
    Human                                  Coordination of
  resources                                   national
                      Research              programmes
                   infrastructures
 COST Actions – what is supported
• Science management meetings

• Scientific workshops and seminars

• Short Term Scientific Missions

• Training Schools and Research Conferences

• Evaluations and Studies

• Dissemination

• http://cost.cordis.lu/src/home.cfm
        FEAST
• Neil.Hamilton@anu.edu.au
       • 02 6125 7690
  • www.feast.org
   • www.cordis.lu
• www.europa.eu.int
  • http://cost.cordis.lu/

				
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posted:4/25/2013
language:English
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