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					                                         Silica-polypeptide Composite Particles
                                    Paul S. Russo, Louisiana State University, DMR 0606117



                                                                              A                           B

                                                                                                          75                                                   HO
                                                                                                                                                      HO
                                                                                                                                                                                   OH


                                                                                                                                                 HO




                                                                                  Surface Tension(mN/m)
                                            C                                                             70
                                                                                                                            D
                                                                                                                                                                    NH                   OH
                                                                                                                                                                         HN
                                                                                                                                                       O                            OH
                 1                                                                                                                     HO
                                                                                                                                                      H
                                                                                                                                                      N                        O
   -1
   Rate /nmh




                                                                                                                                  HO

                                                                                                          65
                                                                                                                                                           O
                                                                                                                                            HO

                                                  Slope = 6.9 ± 0.4
                0.1                                                                                       60


                                                                                                                                                                Half-arborol [9]-6
                                                                                                          55
                                                                                                                       Micelle Formation at
               0.01                                                                                                    concentration = 8.8 mmol/L
                                                                                                          50
                         -4        -3                                    -3
                  8x10        10                                  2x10                                         0   2         4          6                  8                  10          12   14
                                                           -1
                                        Concentration /molL                                                                 Concentration(mmol/L)

The bolaform amphiphile (A) can be thought of as a molecular dumbbell. It spontaneously makes fibers
that are several microns long. These are extruded through a filter (B) and the reassembly (healing) is
monitored. The healing rate is exquisitely sensitive to concentration (C), resembling in that regard sickle
cell hemoglobin. Growth is also affected by the one-directional “tree-like” amphiphile shown lower right
alongside its surface behavior (adapted from Langmuir, 2008, 24(5), 1858-1862). It may be possible to use
this controllable growth to trigger phase transitions in silica-polypeptide composite particles or
other colloidal suspensions, leading to responsive fluids of variable viscosity or clarity.
                            Silica-polypeptide Composite Particles
                         Paul S. Russo, Louisiana State University, DMR 0606117
                                                    Education
Broader impacts                                     Postdoc This Grant Supports
                                                      Dr. Sreelatha Balamurugan
   February 26, 2008 Capitol Middle School
                                                    Students This Grant Supports and Place of Origin
           Baton Rouge, Louisiana
                                                       Erick Soto-Cantu (Mexico);
                                                       Derek Dorman (Mississippi); Brandon Curtiss (Louisiana)
                                                    Undergrads & Current Location
                                                       Wayne Huberty, Senior, University of Wisconsin—Stevens Point
                                                       Richard Rucker, 1st year graduate student, Univ. of Washington Seattle


                                                    Synergistic Activities, Paul S. Russo
                                                    • Co-founder and member, Board of Directors, Louisiana
                                                      Applied Polymer Technology Extension Consortium
The first annual You Be the Chemist Challenge         (APTEC), an inter-university one-stop-shopping economic
to be held in Louisiana, one of 12 states to          development tool. Current interest: getting Governor Jindal
participate so far in the national “spelling bee”
                                                      to approve our board, so we can incorporate as a 501-3c
of chemistry. In addition to the students and
teachers from six middle schools, all of whom         non-profit. Also, writing “HowTo” guide for LSU graduate
studied basic chemistry quite seriously, special      students interested in starting a business.
credit goes to the LSU Cain Center’s Brenda         • Member, Program Committee and Member, Board of
Nixon at right. One of my roles is technical          Trustees, Chemical Education Foundation (Arlington, VA).
advisor to ensure the questions and study             Current interests: revising middle school study guides for the
materials are factually correct, sometimes with
                                                      national You Be the Chemist Challenge. Helped Louisiana
the help of LSU undergrads and graduate
students.                                             field a YBTC team (see image at left).
                                                    • Co-advisor, LSU Student Affiliates of American Chemical
                                                      Society. Trying to help this group find new revenue sources
                                                      through intrapreneurship (providing goods or services for the
             LSU                                      university, for a fee).
             Macromolecular Studies Group

				
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posted:4/17/2013
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