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									ACCOMPLISH: ACE inhibitor plus calcium-channel blocker best for reducing clinical events in hypertensive patients Obese pts with SBP > 160 (at least stage II) or already on antiHTN rx and had evidence of end-organ damage, CV or kidney dz -> put on benazepril + thiazide 12.5mg or amlodipine 5-10mg. Results: -- despite both being good in reducing BP achieving <140/90 levels (>75% in both arms), greater mortality benefit (20% red) was seen in the amlodipine arm. It is thought that this may change current recommendations based largely in ALLHAT results. http://www.theheart.org/viewArticle.do?primaryKey=852911&nl_id=tho10apr08


								
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