Central Cancer Registry Update

Cancer in North Carolina: Central Cancer Registry Karen Knight April 28, 2006 1 Overview of Current Cancer Statistics  Top Ten in Incidence and Mortality  10 year trends  Screening data 2 Number of New Cases North Carolina - 2003 7000 6000 5000 4000 3000 2000 1000 0 Males 2521 5132 1915 Females 5041 3413 2001 Pr os tat e 560 745 282 635 311 Lu ng /B ro Fe nc ma hu le s Br ea st (In va siv e) Co lo n/R ec tu m Me lan om ao fS kin Or al Ca vit y Ce rv ix 3 A Few Numbers      447,149 cases 1990-2003 Currently 35,000 cases each year Approximately 50,000 reports each year 132 hospitals / 43 hospital registries 1,000 physicians queried 2800 times Note: We count cases, not people. 4 NC Cancer Registry Data ■ All rates are age-adjusted unless otherwise indicated ■ Standard population is US 2000 ■ All incidence data are NC 1999-2003 unless otherwise indicated  All mortality data are from 2000-2004 unless otherwise indicated “Colon” = Colon/Rectum “Lung” = Lung/Bronchus “Female Breast” includes in situ ■ Y axis scales vary 5 Top Ten, Cancer Incidence* 160 152 147 Prostate Female Breast Lung/Bronchus 1 140 120 Colon/Rectum 100 Corpus Uteri 80 60 40 20 0 Rate per 100,000 69 48 20 18 16 15 13 11 Bladder Non Hodgkin's Lymphoma Melanoma Kidney Oral Cavity 6 *Age adjusted to the 2000 US Census Top Ten, Cancer Mortality* 1 70 Lung/Bronchus 60 Prostate Female Breast Colon/Rectum Pancreas 30 Ovary 26 18 11 9 7 7 Non-Hodgkin's Lymphoma Leukemia 5 4 Esophagus Brain/Other CNS 7 60 50 Rate per 100,000 40 30 20 10 0 *Age adjusted to the 2000 US Census Rate per 100,000 100 120 140 160 20 40 60 80 0 1 Lung Cancer Incidence 1990-2003 WM WF BM 90 -92 91 -93 92 -94 93 -95 94 -96 95 -97 96 -98 97 -99 98 -00 99 -01 00 -02 01 -03 BF 8 Lung Cancer Mortality 1990-2003 140 120 100 80 60 40 20 0 WM WF BM BF Rate per 100,000 1 2 3 4 5 6 7 8 9 0 1 2 3 - 9 1- 9 2- 9 3- 9 4- 9 5- 9 6- 9 7- 9 8- 0 9- 0 0- 0 1- 0 90 9 9 9 9 9 9 9 9 9 0 0 9 Percent of Current Smokers 10 15 20 25 30 0 5 1 19 19 19 19 19 19 19 19 19 19 20 20 20 20 * Source: BRFSS 10 90 91 92 93 94 95 US 96 97 98 99 00 01 02 03 US vs. NC Smoking Prevalence NC 1 Male Colon Cancer Incidence/Mortality 70 60 Cases/Deaths Per 100,000 50 40 30 20 10 0 WM-Inc BM-Inc WM-Mort BM-Mort 90-92 91-93 92-94 93-95 94-96 95-97 96-98 97-99 98-00 99-01 00-02 01-03 12 Female Colon Cancer Incidence/Mortality 60 1 Rate per 100,000 50 40 30 20 10 0 90-92 91-93 92-94 93-95 94-96 95-97 96-98 97-99 98-00 99-01 00-02 01-03 13 WF-Inc BF-Inc WF-Mort BF-Mort Colon Cancer Stage at Diagnosis (1999-2003) 100% 80% 60% 40% 20% 0% WM Local 6% 7% 8% 9% 17% 16% 21% 19% 40% 41% 39% 40% 37% 37% 32% 33% WF Regional BM Distant Unknown BF 14 Ever had sigmoidoscopy or colonoscopy? BRFSS Survey Results (2001, 2002, 2004) 70 60 50 % Yes 40 30 20 10 0 Male Female Total 2001 2002 2004 15 Ever had sigmoidoscopy or colonoscopy? BRFSS Survey Results (2001, 2002, 2004) 70 60 50 % Yes 40 30 20 10 0 White Black NA Total 2001 2002 2004 16 *Statistically significant, p<.05, 2004, Blacks and Whites Cervical Cancer Incidence/Mortality 20 1 18 16 Wh-Inc Bl-Inc Wh-Mort Bl-Mort Cases/Deaths Per 100,000 14 12 10 8 6 4 2 0 2 3 4 5 6 7 8 9 0 1 2 3 90-9 91-9 92-9 93-9 94-9 95-9 96-9 97-9 98-0 99-0 00-0 01-0 18 Cervical Cancer Mortality Rates 1 16 14 12 10 8 6 4 2 0 WF BF Deaths Per 100,000 0 2 4 6 8 0 2 4 6 8 0 2 198 198 198 198 198 199 199 199 199 199 200 200 19 Stage at Diagnosis Invasive Cervical Cancer (1999-2003) 100% 80% 60% 40% 20% 0% 8% 28% 10% 33% 60% Unknown Distant Regional Local 50% WF BF 20 Women Ages 21+ Who Had Pap Smear in Last 3 Years? 80 60 40 20 0 White Black NA Total % Yes Race BRFSS Survey Results (2004) 21 Female Breast Cancer Incidence/Mortality 180 1 Cases/Deaths Per 100,000 160 140 120 100 80 60 40 20 0 Wh-Inc Bl-Inc Wh-Mort Bl-Mort 90-9 2 91-9 3 4 5 6 7 8 9 0 1 2 3 92-9 93-9 94-9 95-9 96-9 97-9 98-0 99-0 00-0 01-0 23 Female Breast Cancer Stage at Diagnosis (1999-2003) 100% 80% 60% 40% 20% 0% 17% 16% 53% 43% Insitu Local Regional Distant Unknown 3% 24% 31% 6% WF BF 24 Mammogram Within Past 2 Years & Clinical Breast Exam Within a Year 70 60 50 40 30 20 10 0 % Yes White Black NA Total Race (Women >=40 years old) BRFSS Survey Results (2004) 25 Prostate Cancer Incidence/Mortality 300 250 Wh-Inc Bl-Inc Wh-Mort Bl-Mort Cases/ Deaths Per 100,000 1 200 150 100 50 0 90-9 2 92-9 4 94-9 6 96-9 8 98-0 0 2 00-0 27 Prostate Cancer Mortality 1 Rate per 100,000 120 100 80 60 40 20 NC-WM 0 2 3 4 5 6 7 8 9 0 1 2 3 0-9 91-9 92-9 93-9 94-9 95-9 96-9 97-9 98-0 99-0 00-0 01-0 9 28 US-WM NC-BM US-BM Stage at Diagnosis Prostate Cancer (1999-2003) 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 6% 9% 3% 11% 8% 6% Unknown Distant Regional Local 82% 75% WM BM 29 Health Professional Talked With You About Prostate Cancer Screening? 80 60 % Yes 40 20 0 White Black NA Total Race BRFSS Survey Results (2004) 30 Websites www.seer.cancer.gov www.naaccr.org www.cdc.gov/cancer/npcr www.cancer.org www.schs.state.nc.us/SCHS/healthstats 32 Acknowledgements  CDC’s National Program of Cancer Registries  NC CCR Statistical Staff for their analysis 33 How to Contact Us Karen L. Knight Phone: 919-715-4556 E-mail: Karen.Knight@ncmail.net Central Cancer Registry: 919-715-4555 (phone) / 919-733-8485 (fax) http://www.schs.state.nc.us/SCHS/data/cancer.cfm 34 Melanoma: Incidence and Mortality Incidence (99-03) 18.1 14.6 Mortality (00-04) 3.4 2.9 Whites Total  Over 80% diagnosed at local stage 36