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Daniel B. Shin - University of Pennsylvania School of Medicine

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Daniel B. Shin - University of Pennsylvania School of Medicine Powered By Docstoc
					                                Daniel B. Shin
Education
            University of Pennsylvania                                                                 Philadelphia, PA
1998-2002   •   Bachelor of Arts in Biology
                 o Supplemental coursework: German Literature, Business German, Fine Arts
                 o Graduated Cum Laude, Dean’s List
2008-2009   •   Liberal and Professional Studies
                  o Supplemental coursework: Mathematics
2010-2012   •   Master of Science in Biostatistics
                 o Masters thesis advisor: Dr Wei-Ting Wang
2012        •   PhD program in Biostatistics
                 o Academic advisor: Dr Sharon Xie
                 o Research advisor: Dr Russell Shinohara
                 o Research assistantship PI: Dr Joel Gelfand
Work & Research Experience
2010-       Graduate Research Assistantship, U. of Pennsylvania, Dept of Dermatology                Philadelphia, PA
            •   Coordinated the dataset generation and data analysis for the Incident Health Outcomes and Psoriasis
                Events Study (iHOPE) and the Vascular Inflammation in Psoriasis (VIP) Trial
            •   Supervised epidemiology fellows and medical students in statistics and research methodology
            •   Analyzed microarray data for differential gene expression in squamous cell carcinoma and seborrheic
                keratosis (collaboration with Dr John Seykora)
2008-2010   Sr. Research Coordinator & Data Manager, U. of Pennsylvania, Dept of Dermatology            Philadelphia, PA
            •   Oversaw data collection and analysis for comparative effectiveness studies at the Clinical Research
                Unit, including developing case report forms and patient intake forms
            •   Oversaw data collection process for the Pigmented Lesion Group, including supervising up to 5 staff
                members in patient follow-up mailing processing, clinical research data entry, and pathology specimen
                procurement and inventory
            •   Created study-specific databases and created analytical datasets from clinical databases from the
                Hospital of the University of Pennsylvania, the Dermatology Clinical Effectiveness Research Network
                (DCERN), the UK General Practice Research Database (GPRD) and The Health Improvement
                Network (THIN) database
            •   Supervised epidemiology fellows and medical students in statistics and research methodology
2005-2008   Research Coordinator, U. of Pennsylvania, Dept of Dermatology                              Philadelphia, PA
            •   Organized epidemiological studies of melanoma and psoriasis, from reviewing and writing study
                protocols to preparing and analyzing clinical data using various statistical methods
            •   Created study-specific databases for the Pigmented Lesion Group and the Clinical Studies Unit at the
                Hospital of the University of Pennsylvania
            •   Performed database queries and created analytical datasets for various research divisions of the
                Melanoma Core
            •   Advised medical students and research fellows on using statistical packages and data management
            •   Assisted the Editor of the Off-Center Fold of the Archives of Dermatology journal with
                correspondence and journal submissions
2000-2004   Research Specialist, U. of Pennsylvania, Dept of Radiation Oncology                       Philadelphia, PA
            •   Analyzed tissue samples from clinical and preclinical studies for drug levels using HPLC and
                spectrofluorometric assays and created reports
            •   Performed experimental cancer therapies (Photodynamic Therapy and combined treatment
                modalities) on murine models for tumor response follow-ups and tissue collections
            •   Coordinated interdepartmental studies and maintained consistent data flow between collaborators
            •   Created and maintained a research database for tracking animal tumor response studies and tissue
                cataloguing and inventory
            •   Created and maintained a clinical research database for the Phase II Study of Intraperitoneal
                Photodynamic Therapy


                           407 Regatta Drive — Philadelphia, PA 19146 — 215.839.6806
                                           dbshin@mail.med.upenn.edu
                                                    Daniel B. Shin

             •    Assisted in the development of HPLC and spectrofluorometric assays for analyzing tissue drug
                  concentrations
Skills and Certifications
             Computer and Analytical Expertise
             •    Extensive knowledge of MS Windows-based operating systems and networks, hardware and software
             •    Excellent command of statistical software and methodology using Stata, R and SAS, and database
                  operations and development using SQL and VBA
             •    MS Office, Matlab, SPSS, Adobe Photoshop, IPLab, SEER*Stat, mySQL, Oracle, PHP,
                  Dreamweaver, EndNote
             Clinical Research and Laboratorial Expertise
             •    Good command of clinical research protocols and HIPAA compliancy, extensive experience with
                  patient data collection and organization, IRB protocol submissions
             •    Patient Oriented Research Full Review Certification and CITI Certification
             •    Excellent knowledge of publicly available medical research databases: SEER, NHANES, NHIS,
                  GPRD, THIN
             •    Excellent command of data management, case report form development, dataset creation and analysis
             •    Various tissue digestion assays, HPLC, fluorometry, spectrofluorometry, fluorescence microscopy,
                  cryostat slide preparation, sterile technique cell culturing and maintenance, medical laser operations
             •    Animal techniques including eye, IP and tailvein injections, tumoring, anesthesia, and general care
             Foreign Languages
             •    Written and spoken fluency in German, with extensive usage abroad
             •    Zertificat Deutsch für den Beruf, Certification for Business German (May 2000)
                  Excellent command of German business customs and technical terminologies
             •    Good command of spoken Korean, proficient in writing
Personal Interests
             Hobbies
             •    Ultimate Frisbee, Piano, Travelling, Literature & Informatics
             Activities
             •    Tutoring high school, college and post-baccalaureate students
Publications and Presentations
             Publications
             •    Abuabara K, Wan J, Troxel AB, Shin DB, Van Voorhees AS, Bebo BF Jr, Krueger GG, Duffin KC,
                  Gelfand JM. Variation in dermatologist beliefs about the safety and effectiveness of treatments for
                  moderate to severe psoriasis. J Am Acad Dermatol. 2012 Aug 18. [Epub ahead of print]
             •    Yeung H, Wan J, Van Voorhees AS, Callis Duffin K, Krueger GG, Kalb RE, Weisman JD, Sperber
                  BR, Brod BA, Schleicher SM, Bebo BF Jr, Shin DB, Troxel AB, Gelfand JM. Patient-reported
                  reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis. J Am
                  Acad Dermatol. 2012 Jul 28. [Epub ahead of print]
             •    Azfar RS, Seminara NM, Shin DB, Troxel AB, Margolis DJ, Gelfand JM. Increased risk of diabetes
                  mellitus and likelihood of receiving diabetes mellitus treatment in patients with psoriasis. Arch
                  Dermatol. 2012 Jun 18:1-6.
             •    Wan J, Abuabara K, Troxel AB, Shin DB, Van Voorhees AS, Bebo BF Jr, Krueger GG, Callis Duffin
                  K, Gelfand JM. Dermatologist preferences for treatments to compare in future randomized
                  controlled comparative effectiveness trials for moderate to severe psoriasis. Arch Dermatol. 2012
                  Apr;148(4):539-41.
             •    Arkin LM, Flory JH, Shin DB, Gelfand JM, Treat JR, Allen J, Rubenstein RC, Yan AC. High
                  prevalence of aquagenic wrinkling of the palms in patients with cystic fibrosis and association with
                  measurable increases in transepidermal water loss. Pediatr Dermatol. 2012 Apr 4.
             •    Gelfand JM, Wan J, Callis Duffin, K, Krueger GG, Kalb RE, Weisman JD, Sperber BR, Stierstorfer
                  MB, Brod BA, Schleicher SM, Bebo BF, Troxel AB, Shin DB, Steinemann JM, Goldfarb J, Yeung H,
                  Van Voorhees AS. Comparative effectiveness of commonly used systemic treatments or


                          2321 Spruce Street Apt 1R — Philadelphia, PA 19103 — 215.839.6806
                                              dbshin@mail.med.upenn.edu
                                      Daniel B. Shin

    phototherapy for moderate to severe plaque psoriasis in the clinical practice setting. Arch Dermatol.
    2012 Apr;148(4):487-94.
•   Langan SM, Seminara NM, Shin DB, Troxel AB, Kimmel SE, Mehta NN, Margolis DJ, Gelfand JM.
    Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United
    Kingdom. J Invest Dermatol. 2011 Nov 24. [Epub ahead of print]
•   Wan J, Abuabara K, Troxel AB, Shin DB, Van Vorhees AS, Bebo BF, Krueger GG, Duffin KC,
    Gelfand JM. Dermatologist preferences for first-line therapy of moderate-to-severe psoriasis in
    healthy adult patients. J Am Acad Dermatol. 2012 Mar;66(3):376-86.
•   Wan J, Abuabara K, Shin DB, Troxel AB, Bebo BF, Gelfand JM. Dermatologist response rates to a
    mailed questionnaire: a randomized trial of monetary incentives. J Am Acad Dermatol. 2012
    Jan;66(1):e18-20.
•   Raphael BA, Shin DB, Suchin KR, Morrissey KA, Vittorio CC, Kim EJ, Gardner JM, Evans KG,
    Introcaso CE, Samimi SS, Gelfand JM, Rook AH. High clinical response rate of Sezary Syndrome to
    immunomodulatory therapies: prognostic markers of response. Arch Dermatol. 2011
    Dec;147(12):1410-5. Epub 2011 Aug 15.
•   Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM. Attributable
    risk estimate of severe psoriasis on major cardiovascular events. Am J Med. 2011 Aug;124(8):775.e1-
    6.
•   Dommasch ED, Abuabara K, Shin DB, Nguyen J, Troxel AB, Gelfand JM. The risk of infection and
    malignancy with tumor necrosis factor antagonists in adult patients with psoriatic disease: a
    systematic review and meta-analysis of randomized controlled trials. J Am Acad Dermatol. 2011
    Jun;64(6):1035-50. Epub 2011 Feb 18.
•   Seminara NM, Abuabara K, Shin DB, Langan SM, Kimmel SE, Margolis D, Troxel AB, Gelfand JM.
    Validity of The Health Improvement Network (THIN) for the study of psoriasis. Br J Dermatol.
    2011 Mar;164(3):602-9.
•   Abuabara K, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM. Cause-specific mortality in
    patients with severe psoriasis: A population-based cohort study in the United Kingdom. Br J
    Dermatol. 2010 Sep;163(3):586-92.
•   Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM. Patients with severe psoriasis
    are at increased risk of cardiovascular mortality: cohort study using the General Practice Research
    Database. Eur Heart J. 2010 Apr;31(8):1000-6.
•   Dommasch E, Shin DB, Troxel AB, Margolis DJ, Gelfand JM. Reliability, Validity, and
    Responsiveness to Change of the Patient Report of Extent of Psoriasis Involvement (PREPI) for
    Measuring Body Surface Area Affected by Psoriasis. Br J Dermatol. 2010 Apr;162(4):835-42.
•   Brauer JB, Wriston CC, Troxel AB, Elenitsas R, Shin DB, Guerry D, Ming ME. Characteristics
    associated with early and late melanoma metastases. Cancer. 2010 Jan 15;116(2):415-23.
•   Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel AB. The risk of stroke
    in patients with psoriasis. J Invest Dermatol. 2009 Oct;129(10):2411-8. Epub 2009 May 21.
•   Lee RA, Dommasch E, Treat J, Sciacca-Kirby J, Chachkin S, Williams J, Shin DB, Leyden JJ, Vittorio
    C, Gelfand JM. A prospective clinical trial of open-label etanercept for the treatment of hidradenitis
    suppurativa. J Am Acad Dermatol. 2009 Apr;60(4):565-73. Epub 2009 Jan 31.
•   Smith N, Shin DB, Brauer JA, Mao J, Gelfand JM. Use of complementary and alternative medicine
    among adults with skin disease: results from a national survey. J Am Acad Dermatol. 2009
    Mar;60(3):419-25. Epub 2009 Jan 20.
•   Jambusaria-Pahlajani A, Schmults CD, Miller CJ, Shin D, Williams J, Kurd SK, Gelfand JM. Test
    characteristics of high-resolution ultrasound in the preoperative assessment of margins of basal cell
    and squamous cell carcinoma in patients undergoing Mohs micrographic surgery. Dermatol Surg.
    2009 Jan;35(1):9-15; discussion 15-6. Epub 2008 Nov 19.
•   Brauer JA, Shin DB, Troxel AB, Shapiro M, Levy RM, Ming ME. Characteristics of dermatologists
    who read dermatopathology slides. J Cutan Pathol. 2007 Sep;34(9):687-92.
•   Gelfand JM, Troxel AB, Lewis JD, Kurd SK, Shin DB, Wang X, Margolis DJ, Strom BL. The risk of
    mortality in patients with psoriasis: results from a population-based study. Arch Dermatol. 2007
    Dec;143(12):1493-9.
•   Clark LN, Shin DB, Troxel AB, Khan S, Sober AJ, Ming ME. Association between the anatomic
    distribution of melanoma and sex. J Am Acad Dermatol. 2007 May;56(5):768-73. Epub 2007 Mar 6.
•   Neimann, AL, Shin, DB, Wang, X, Margolis, DJ, Troxel, AB and Gelfand, JM. Prevalence of


          2321 Spruce Street Apt 1R — Philadelphia, PA 19103 — 215.839.6806
                              dbshin@mail.med.upenn.edu
                                      Daniel B. Shin

    cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol. 2006 Nov;55(5):829-35.
    Epub 2006 Sep 25.
•   Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction
    in patients with psoriasis. JAMA. 2006 Oct 11;296(14):1735-41.
•   Hahn SM, Putt ME, Metz J, Shin DB, Rickter E, Menon C, Smith D, Glatstein E, Fraker DL, Busch
    TM. Photofrin uptake in the tumor and normal tissues of patients receiving intraperitoneal
    photodynamic therapy. Clin Cancer Res. 2006 Sep 15;12(18):5464-70.
•   Gelfand JM, Shin DB, Neimann AL, Wang X, Margolis DJ, Troxel AB. The Risk of Lymphoma in
    Patients with Psoriasis. J Invest Dermatol. 2006 Oct;126(10):2194-201. Epub 2006 Jun 1.
•   Hahn SM, Fraker DL, Mick R, Busch TM, Smith D, Zhu T, Rodriquez C, Dimofte A, Spitz F, Putt
    M, Rubin SC, Menon C, Wang HW, Shin D, Yodh A, Glatstein E. A phase II trial of intraperitoneal
    photodynamic therapy for patients with peritoneal carcinomatosis and sarcomatosis. Clin Cancer Res
    2006;12(8):2517-25.
•   Wang HW, Putt ME, Emanuele MJ, Shin DB, Glatstein E, Yodh AG, Busch TM. Treatment-induced
    changes in tumor oxygenation predict photodynamic therapy outcome. Cancer Res 2004;64(20):7553-
    61.
•   Busch TM, Hahn SM, Wileyto EP, Koch CJ, Fraker DL, Zhang P, Putt M, Gleason K, Shin DB,
    Emanuele MJ, Jenkins K, Glatstein E, Evans SM. Hypoxia and Photofrin uptake in the
    intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clin Cancer Res
    2004;10(14):4630-8.
•   Friedberg JS, Mick R, Stevenson JP, Zhu T, Busch TM, Shin D, Smith D, Culligan M, Dimofte A,
    Glatstein E, Hahn SM. Phase II trial of pleural photodynamic therapy and surgery for patients with
    non-small-cell lung cancer with pleural spread. J Clin Oncol 2004;22(11):2192-201.
Presentations and Abstracts
•   Second primary melanomas have similar characteristics to the initial primary melanoma on the same
    patient. Ming ME, Shin DB. Annual Meeting of the Society for Investigative Dermatology, Atlanta,
    GA. 2010. (oral presentation)
•   High clinical response rate of Sezary syndrome with immune modifying therapies: Prognostic markers
    of response. BA Raphael, DB Shin, KR Suchin, K Morrissey, C Vittorio, E Kim, J Gardner, K Evans,
    C Introcaso, JM Gelfand, AH Rook. SID, Atlanta, GA. 2010. (oral presentation)
•   Cause-specific mortality in severe psoriasis: A cohort study using the general practice research
    database. K Abuabara, RS Azfar, DB Shin, AL Neimann, AB Troxel, JM Gelfand. SID, Atlanta, GA.
    2010.
•   Prevalence of psoriasis severity and predictive value of psoriasis codes in The Health Improvement
    Network (THIN)– a population based study. N Seminara, K Abuabara, D Shin, S Kimmel, DJ
    Margolis, AB Troxel, JM Gelfand. SID, Atlanta, GA. 2010. (oral presentation)
•   Patients With Severe Psoriasis and No History of Cardiovascular Disease Are at Increased Risk of
    Cardiovascular Mortality. NN Mehta, RS Azfar, DB Shin, AL Neimann, AB Troxel, JM Gelfand.
    American Heart Association Scientific Sessions, Orlando, FL. 2009.
•   Reliability and validity of the Patient Report of Extent of Psoriasis Involvement (PREPI) for
    determining psoriasis severity. Dommasch E, Shin DB, Troxel AB, Margolis DJ, Gelfand JM. SID,
    Montreal, Canada. 2009.
•   A prospective clinical trial of open label etanercept for the treatment of hidradenitis suppurativa.
    Dommasch E, Lee RA, Treat J, Sciacca-Kirby J, Cachkin S, Williams J, Shin DB, Leyden J, Vittorio C,
    Gelfand JM. SID, Montreal, Canada. 2009.
•   Tumor infiltrating lymphocytes are a prognostic marker for survival in patients who develop
    melanoma metastases. Wriston CC, Troxel AB, Shin DB, Schaffer A, Rubin AI, Brauer JA, Ming
    ME. SID, Montreal, Canada. 2009.
•   Risk of cardiovascular mortality in patients with severe psoriasis. Azfar RS, Neimann AL, Shin DB,
    Troxel AB, Gelfand JM. SID, Montreal, Canada. 2009.
•   Prevalence of atherosclerotic diseases in patients with psoriasis: a population-based study using the
    General Practice Research Database. Gelfand JM, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel
    AB. International Investigative Dermatiology (IID), Kyoto, Japan. 2008. (oral presentation)
•   Incidence of stroke in patients with psoriasis: a population-based study. Gelfand JM, Azfar, RS. Shin
    D, Kurd SK, Wang X, Troxel AB. IID, Kyoto, Japan. 2008.


         2321 Spruce Street Apt 1R — Philadelphia, PA 19103 — 215.839.6806
                             dbshin@mail.med.upenn.edu
                                       Daniel B. Shin

•   An examination of the relationship between melanoma and other malignancies using the Surveillance,
    Epidemiology and End Results (SEER) Registry. Shin DB, Brauer JA, Cooper CC, Troxel AB, Ming
    ME. SID, Los Angeles, CA. 2007. (oral presentation)
•   Patients with severe psoriasis have an increased risk of mortality. Kurd SK, Lewis JL, Troxel AB,
    Margolis DJ, Strom BL, Shin DB, Wang X, Gelfand JM. SID, Los Angeles, CA. 2007.
•   Solar elastosis is not associated with melanoma metastasis. Wriston CC, Brauer JA, Hudacek KD,
    Rubin AI, Schaffer A, Shin DB, Troxel AB, Ming ME. SID, Los Angeles, CA. 2007.
•   A multivariate model for development of second primary melanoma. Shin DB, Brauer JA, Troxel AB
    Khan S, Ming ME. Perspectives in Melanoma X and the Third International Melanoma Research
    Congress, Noordwijk, the Netherlands. 2006.
•   A prognostic model for development of second primary melanoma. Shin DB, Brauer JA, Troxel AB
    Khan S, Ming ME. SID, Philadelphia, PA. 2006. (oral presentation)
•   Statins, non-steroidal anti-inflammatory drugs (NSAIDs) and calcium channel blockers (CCBs) are
    prescribed less frequently for patients who later develop melanoma. Ming ME, Shin DB, Brauer JA,
    Troxel AB. SID, Philadelphia, PA. 2006.
•   Characteristics associated with early and late melanoma metastases. Brauer JA, Troxel AB, Shin DB,
    Ming ME. SID, Philadelphia, PA. 2006.
•   The increased risk of myocardial infarction in patients with psoriasis. Gelfand JM, Neimann AL, Shin
    DB, Wang X, Margolis DJ, Troxel AB. SID, Philadelphia, PA 2006.
•   Prevalence of cardiovascular risk factors in patients with psoriasis: a population-based study using the
    General Practice Research Database. Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB,
    Gelfand JM. SID, Philadelphia, PA. 2006.
•   Use of complementary and alternative medicine (CAM) among adults with skin disease: results from a
    national survey. Smith N, Shin DB, Mao J. Society for Investigative Dermatology. 2006.
•   Association between the anatomic distribution of melanoma and sex. Clark LN, Shin DB, Troxel A,
    Sober A, Ming ME. SID, St. Louis, MO. 2005.
•   Statins, non-steroidal anti-inflammatory drugs (NSAIDs) and calcium channel blockers (CCBs) are
    prescribed less frequently for patients who later develop melanoma. Ming ME, Shin DB, Brauer JA,
    Troxel A. Keystone Symposia. 2005.
•   Characterization of dermatologists who read dermatopathology slides. Ming ME, Brauer JA, Shin DB,
    Levy RM, Shapiro M. The American Society of Dermatolopathology. 2005.




          2321 Spruce Street Apt 1R — Philadelphia, PA 19103 — 215.839.6806
                              dbshin@mail.med.upenn.edu

				
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