Uses of Biosensors by xiaoyounan


     Anthony Carr
      Brett Gobe
     Ben LaPierre
What are biosensors?
 Detectors based on selective molecular
  components of plants or animals.
 Modern Biosensors evolved from 2 different
       Molecular Biology
       Information Technology.
   Offers a wide variety of applications.
       Medical
       Environmental
       Military / Law Enforcement
Evolution of the Medical
 Mid 1950’s - Leland C Clark invents an
  electrode that measures dissolved oxygen in
  the blood of patients undergoing surgery.
 He surrounded a platinum electrode and
  reference electrode with a plastic membrane
  permeable to gases. The voltage differential
  measured between the two gave the rate at
  which the oxygen was being diffused.
   Clark extended this electrode idea to include glucose
   However these never made their way into routine patient
    care. This was due to flaws in accuracy when clots
    formed around the electrode.
Required Characteristics
    Sensitivity               Utility
    Low detection limits      Field portability
    Cost                      Ruggedness
    Simplicity                Reproducibility
    Reliability               Ease of calibration
    Speed                     Stability
    Accuracy                  Room for
    Precision                  improvement
  Combine a biological compound with a
  What is a transducer?
Flow Injection Analysis
    What is FIA?
Uses of Biosensors
  Environmental Monitoring
  Military
  Law Enforcement
  Medical
Present Applications of
  Medical Care (both clinical and
   laboratory use)
  The determination of food quality
  The detection of environmental
  Industrial Process Control
Applications (cont’d.)
 Biosensors in process control will be able to measure
  materials in the process flow of temperature, pressure
  and the acidity readings.
 The development of biosensors in industry can
  improve manufacturing techniques, which would allow
  for a wider range of sensing molecules to be
  produced at a cheaper rate.
 In the field of medicine, tumor cells are used as a
  biosensor to monitor chemotherapeutic drug
 Biosensors also play a role in the manufacturing of
  pharmaceuticals and replacement organs such as an
  artificial pancreas for diabetics.
 It is found that biosensors are widely used in
  environmental testing by using a “flow-
  through” system to monitor wastewater (a
  flow-through system includes instruments
  using surface plasmon resonance).
 These censors are not only restricted to the
  use of molecules. Rather living
  microorganisms such as bacteria can be used
  to detect substances such as vitamin B12.
 Conclusively, biosensors play a part in the
  field of medicine, environmental quality, and
  industry mainly by identifying material and
  the degree of concentration present.

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