Table st1_ XLSX - mBio

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Table st1_ XLSX - mBio Powered By Docstoc
					Z value   Gene Symbol   Accession   Gene Name                      GO Molecular Function
-2.30     76P           NM_014444                                  structural constituent of cytoskeleton;microtubule
                                    Gamma-tubulin complex component 4;TUBGCP4;ortholog
-2.40     AAAS          NM_015665   Aladin;AAAS;ortholog
-2.03     AASS          NM_005763                                  oxidoreductase
                                    Saccharopine dehydrogenase;AASS;ortholog activity
2.45      ABCB9         NM_019624                                  ATPase activity, coupled to transmembrane move
                                    ATP-binding cassette sub-family B member 9;ABCB9;ortholog
-2.43     ABCC3         NM_003786                                  ATPase activity, coupled to transmembrane move
                                    Canalicular multispecific organic anion transporter 2;ABCC3;ortholog
-2.77     ABCG2         NM_004827                                  transmembrane transporter activity
                                    ATP-binding cassette sub-family G member 2;ABCG2;ortholog
3.13      ABHD1         NM_032604                                  hydrolase activity
                                    Abhydrolase domain-containing protein 1;ABHD1;ortholog
2.64      ABHD14A       NM_015407                                  serine-type peptidase activity
                                    Abhydrolase domain-containing protein 14A;ABHD14A;ortholog
-2.25     ABHD14B       NM_032750                                  serine-type peptidase activity
                                    Abhydrolase domain-containing protein 14B;ABHD14B;ortholog
10.29     ABHD3         NM_138340                                  hydrolase activity
                                    Abhydrolase domain-containing protein 3;ABHD3;ortholog
-2.46     ABLIM1        NM_002313                                  structural constituent of cytoskeleton
                                    Actin-binding LIM protein 1;ABLIM1;ortholog
2.19      ACAA1         NM_001607                                  transferase activity
                                    3-ketoacyl-CoA thiolase, peroxisomal;ACAA1;ortholog
-2.06     ACADL         NM_001608                                  oxidoreductase activity
                                    Long-chain specific acyl-CoA dehydrogenase, mitochondrial;ACADL;ortholog
-2.33     ACOT7         NM_007274                                  hydrolase activity, acting on ester
                                    Cytosolic acyl coenzyme A thioester hydrolase;ACOT7;ortholog bonds
2.58      ACP1          NM_004300                                  phosphoprotein phosphatase activity;phosphopro
                                    Low molecular weight phosphotyrosine protein phosphatase;ACP1;ortholog
-2.93     ACP5          NM_001611   Tartrate-resistant acid phosphatase type 5;ACP5;ortholog
-2.15     ACPL2         NM_152282   Acid phosphatase-like protein 2;ACPL2;ortholog
2.09      ACSL6         NM_015256                                  ligase activity
                                    Long-chain-fatty-acid--CoA ligase 6;ACSL6;ortholog
-2.64     ACTB          NM_001101                                  structural constituent of cytoskeleton
                                    Actin, cytoplasmic 1;ACTB;ortholog
2.75      ACTG2         NM_001615                                  structural constituent of
                                    Actin, gamma-enteric smooth muscle;ACTG2;ortholog cytoskeleton
3.06      ACTL6         NM_016188                                  structural
                                    Actin-like protein 6B;ACTL6B;ortholog constituent of cytoskeleton
2.18      ACTN2         NM_001103   Alpha-actinin-2;ACTN2;ortholog structural constituent of cytoskeleton;actin binding
-2.59     ACTR2         NM_005722                                  structural
                                    Actin-related protein 2;ACTR2;ortholog constituent of cytoskeleton
-2.93     ACTR3         NM_005721                                  structural
                                    Actin-related protein 3;ACTR3;ortholog constituent of cytoskeleton
7.69      ACVR2         NM_001616                                  transmembrane receptor protein kinase activity;tr
                                    Activin receptor type-2A;ACVR2A;ortholog
-2.52     ACY1          NM_000666   Aminoacylase-1;ACY1;orthologmetallopeptidase activity
2.63      ADAL          XM_091156                                  hydrolase activity;deaminase activity
                                    Adenosine deaminase-like protein;ADAL;ortholog
-2.44     ADAMTS1       NM_006988                                  metallopeptidase activity
                                    A disintegrin and metalloproteinase with thrombospondin motifs 1;ADAMTS1;ort
-2.13     ADAMTS14      NM_080722                                  metallopeptidase activity
                                    A disintegrin and metalloproteinase with thrombospondin motifs 14;ADAMTS14;
2.73      ADAMTS6       NM_014273                                  metallopeptidase activity
                                    A disintegrin and metalloproteinase with thrombospondin motifs 6;ADAMTS6;ort
10.74     ADC           NM_052998   Arginine decarboxylase;ADC;ortholog
                                                                   carboxy-lyase activity
-2.37     ADD3          NM_016824                                  s
                                    Gamma-adducin;ADD3;orthologtructural constituent of cytoskeleton;actin binding
2.97      ADH1C         NM_000669                                  oxidoreductase
                                    Alcohol dehydrogenase 1C;ADH1C;ortholog activity
3.26      ADH6          NM_000672                                  oxidoreductase activity
                                    Alcohol dehydrogenase 6;ADH6;ortholog
5.50      ADI1          NM_018269   1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase;ADI1;ortholog
                                                                   oxidoreductase activity
2.81      ADIPOR1       NM_015999                                  receptor activity
                                    Adiponectin receptor protein 1;ADIPOR1;ortholog
2.84      ADNP          NM_015339   Activity-dependent neuroprotector homeobox protein;ADNP;ortholog
-2.13     ADPRTL1       NM_006437                                  protein binding;serine-type endopeptidase inhibito
                                    Poly [ADP-ribose] polymerase 4;PARP4;ortholog
2.62      AFAF          XM_035953   Acrosome formation-associated factor;AFAF;ortholog
3.78      AGER          NM_001136                                  receptor activity
                                    Advanced glycosylation end product-specific receptor;AGER;ortholog
-2.74     AGL           NM_000028                                  transferase
                                    Amylo-alpha-1,6-glucosidase;AGL;orthologactivity, transferring glycosyl groups;h
4.13      AGPAT2        NM_006412                                   acyltransferase beta;AGPAT2;ortholog
                                    1-acyl-sn-glycerol-3-phosphateacyltransferase activity
-2.49     AGXT          NM_000030                                  transaminase activity
                                    Serine--pyruvate aminotransferase;AGXT;ortholog
2.80      AHCY          NM_000687                                  hydrolase
                                    Adenosylhomocysteinase;AHCY;ortholog activity
-2.73     AIPL1         NM_014336   Aryl-hydrocarbon-interacting protein-like 1;AIPL1;ortholog
2.69      AK1           NM_000476                                  nucleotide kinase activity
                                    Adenylate kinase isoenzyme 1;AK1;ortholog
-2.57     AKR7A2        NM_003689                                  oxidoreductase activity
                                    Aflatoxin B1 aldehyde reductase member 2;AKR7A2;ortholog
2.70      ALAS1         NM_000688                                  transferase activity
                                    5-aminolevulinate synthase, nonspecific, mitochondrial;ALAS1;ortholog
-2.32   ALAS2      NM_000032                                   transferase activity
                               5-aminolevulinate synthase, erythroid-specific, mitochondrial;ALAS2;ortholog
-2.72   ALDH1B1    NM_000692                                   oxidoreductase activity
                               Aldehyde dehydrogenase X, mitochondrial;ALDH1B1;ortholog
-2.91   ALDH2      NM_000690                                   oxidoreductase activity
                               Aldehyde dehydrogenase, mitochondrial;ALDH2;ortholog
-2.23   ALDH9A1    NM_000696                                    dehydrogenase;ALDH9A1;ortholog
                               4-trimethylaminobutyraldehyde oxidoreductase activity
6.64    ALDOA      NM_000034                                   lyase activity
                               Fructose-bisphosphate aldolase A;ALDOA;ortholog
-2.27   ALKBH      NM_006020   Alkylated DNA repair protein alkB homolog 1;ALKBH1;ortholog
2.57    ALS2CR17   NM_198945                                   protein binding
                               Neurobeachin-like protein 1;NBEAL1;ortholog
-2.64   ALS2CR3    NM_015049   Trafficking kinesin-binding protein 2;TRAK2;ortholog
-2.48   ALS2CR8    NM_024744   Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein;AL
3.06    ALX1       NM_006982                                   transcription factor activity;transcription factor act
                               ALX homeobox protein 1;ALX1;ortholog
-2.96   AMDHD2     NM_015944                                   deacetylase deacetylase;AMDHD2;ortholog
                               Putative N-acetylglucosamine-6-phosphate activity
3.48    AMPD3      NM_000480   AMP deaminase 3;AMPD3;ortholog  hydrolase activity;deaminase activity
-2.45   AMT        NM_000481                                   oxidoreductase activity
                               Aminomethyltransferase, mitochondrial;AMT;ortholog
-2.09   ANAPC1     NM_022662                                   ligase activity
                               Anaphase-promoting complex subunit 1;ANAPC1;ortholog
-3.27   ANGEL2     NM_144567   Protein angel homolog 2;ANGEL2;ortholog
2.74    ANKRD10    NM_017664   Ankyrin repeat domain-containing protein 10;ANKRD10;ortholog
-2.34   ANKRD31    XM_293911   Ankyrin repeat domain-containing protein 31;ANKRD31;ortholog
-2.68   ANP32C     NM_012403                                   protein binding;phosphatase inhibitor activity;phos
                               Acidic leucine-rich nuclear phosphoprotein 32 family member C;ANP32C;ortholo
-2.22   ANPEP      NM_001150   Aminopeptidase N;ANPEP;ortholog metallopeptidase activity
-2.21   AP3B1      NM_003664   AP-3 complex subunit beta-1;AP3B1;ortholog
3.37    APC        NM_000038                                   structural constituent
                               Adenomatous polyposis coli protein;APC;ortholog of cytoskeleton;microtubule
2.58    APEH       NM_001640                                   serine-type peptidase activity
                               Acylamino-acid-releasing enzyme;APEH;ortholog
2.62    APEX2      NM_014481                                   exodeoxyribonuclease activity;endodeoxyribonuc
                               DNA-(apurinic or apyrimidinic site) lyase 2;APEX2;ortholog
-2.17   APG12L     NM_004707   Autophagy-related protein 12;ATG12;ortholog
-3.17   APOA2      NM_001643                                   lipid transporter activity;transmembrane transport
                               Apolipoprotein A-II(1-76);APOA2;ortholog
-2.56   APOC4      NM_001646   Apolipoprotein C-IV;APOC4;ortholog
-2.51   APOL1      NM_003661                                   lipid
                               Apolipoprotein L1;APOL1;ortholog transporter activity;transmembrane transport
-2.93   APOL2      NM_030882                                   lipid
                               Apolipoprotein L2;APOL2;ortholog transporter activity;transmembrane transport
2.10    APOL5      NM_030642                                   lipid
                               Apolipoprotein L5;APOL5;ortholog transporter activity;transmembrane transport
3.19    AQP3       NM_004925   Aquaporin-3;AQP3;ortholog transmembrane transporter activity
2.44    AR         NM_000044   Aldose reductase;AKR1B1;orthologoxidoreductase activity
-2.86   ARF1       NM_001658                                   GTPase
                               ADP-ribosylation factor 1;ARF1;orthologactivity;protein binding
-2.23   ARFIP1     NM_014447   Arfaptin-1;ARFIP1;ortholog      protein binding;small GTPase regulator activity
-3.45   ARHE       NM_005168                                   GTPase activity;protein
                               Rho-related GTP-binding protein RhoE;RND3;ortholog binding
-3.26   ARHGAP1    NM_004308                                    1;ARHGAP1;ortholog
                               Rho GTPase-activating proteinprotein binding;small GTPase regulator activity
-2.18   ARHGAP18   NM_033515                                    18;ARHGAP18;ortholog
                               Rho GTPase-activating proteinprotein binding;small GTPase regulator activity
2.50    ARHGAP6    NM_001174                                    6;ARHGAP6;ortholog
                               Rho GTPase-activating proteinstructural constituent of cytoskeleton
3.65    ARHGDIA    NM_004309                                    1;ARHGDIA;ortholog
                               Rho GDP-dissociation inhibitor receptor binding;small GTPase regulator activity
-2.00   ARHGDIB    NM_001175                                    2;ARHGDIB;ortholog
                               Rho GDP-dissociation inhibitor receptor binding;small GTPase regulator activity
3.13    ARL2       NM_001667                                   GTPase activity;protein
                               ADP-ribosylation factor-like protein 2;ARL2;ortholog binding
-2.25   ARPC3      NM_005719                                   structural 3;ARPC3;ortholog
                               Actin-related protein 2/3 complex subunitconstituent of cytoskeleton
-2.70   ARPC4      NM_005718                                   structural 4;ARPC4;ortholog
                               Actin-related protein 2/3 complex subunitconstituent of cytoskeleton
3.10    ARPC5      NM_005717                                   structural 5;ARPC5;ortholog
                               Actin-related protein 2/3 complex subunitconstituent of cytoskeleton
3.20    ARPP-19    NM_006628   cAMP-regulated phosphoprotein 19;ARPP19;ortholog
-2.78   ARRDC1     NM_152285   Arrestin domain-containing protein 1;ARRDC1;ortholog
3.13    ARSD       NM_001669   Arylsulfatase D;ARSD;orthologhydrolase activity
2.45    ARSI       XM_291139   Arylsulfatase I;ARSI;ortholog hydrolase activity
-2.11   ASPA       NM_000049   Aspartoacylase;ASPA;orthologmetallopeptidase activity;deacetylase activity
2.53    ASPH       NM_004318                                   oxidoreductase activity
                               Aspartyl/asparaginyl beta-hydroxylase;ASPH;ortholog
3.32    ASPHD1     NM_181718                                    oxidoreductase protein
                               Aspartate beta-hydroxylase domain-containing activity 1;ASPHD1;ortholog
-2.17   ATAD1      NM_032810                                    hydrolase activity
                               ATPase family AAA domain-containing protein 1;ATAD1;ortholog
-2.08   ATAD2      NM_014109                                    hydrolase activity
                               ATPase family AAA domain-containing protein 2;ATAD2;ortholog
-2.06   ATF6       NM_007348                                    transcription factor activity;transcription factor act
                               Processed cyclic AMP-dependent transcription factor ATF-6 alpha;ATF6;ortholo
-2.26   ATF7IP2    NM_024997   Activating transcription factor 7-interacting protein 2;ATF7IP2;ortholog
3.58    ATM        NM_138293                                    protein kinase activity;nucleotide kinase activity;n
                               Serine-protein kinase ATM;ATM;ortholog
3.41    ATP10A     NM_024490                                    hydrolase activity;transmembrane
                               Probable phospholipid-transporting ATPase VA;ATP10A;ortholog transporter act
2.41    ATP2A1     NM_004320                                    hydrolase activity;cation transmembrane transpor
                               Sarcoplasmic/endoplasmic reticulum calcium ATPase 1;ATP2A1;ortholog
2.84    ATP5S      NM_015684                                    cation transmembrane transporter activity;hydrog
                               ATP synthase subunit s, mitochondrial;ATP5S;ortholog
5.88    ATP5SL     NM_018035   ATP synthase subunit s-like protein;ATP5SL;ortholog
-2.66   ATP6V1A    NM_001690                                     subunit A;ATP6V1A;ortholog
                               V-type proton ATPase catalytichydrolase activity;cation transmembrane transpor
-2.36   ATP6V1B1   NM_001692                                    hydrolase activity;cation transmembrane
                               V-type proton ATPase subunit B, kidney isoform;ATP6V1B1;ortholog transpor
-3.30   ATP6V1D    NM_015994                                    hydrolase activity;cation transmembrane transpor
                               V-type proton ATPase subunit D;ATP6V1D;ortholog
4.37    ATP7B      NM_000053   WND/140 kDa;ATP7B;orthologhydrolase activity;cation transmembrane transpor
2.23    ATP8B3     NM_138813                                    hydrolase activity;transmembrane
                               Probable phospholipid-transporting ATPase IK;ATP8B3;ortholog transporter act
-2.09   ATXN2L     NM_007245                                    RNA binding
                               Ataxin-2-like protein;ATXN2L;ortholog
-2.03   AURKB      NM_004217                                    protein kinase activity
                               Serine/threonine-protein kinase 12;AURKB;ortholog
2.04    AX2R       XM_371738   Annexin-2 receptor;AX2R;ortholog
-2.55   AXIN1      NM_003502   Axin-1;AXIN1;ortholog            protein binding;small GTPase regulator activity
3.11    B3GAT1     NM_018644                                    transferase activity, transferring glycosyl groups
                               Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;B3GAT1;or
2.17    BACH2      NM_021813                                    transcription factor activity;transcription factor act
                               Transcription regulator protein BACH2;BACH2;ortholog
-3.00   BAGE4      NM_181704   B melanoma antigen 4;BAGE4;ortholog
-2.32   BAK1       NM_001188                                    receptor binding
                               Bcl-2 homologous antagonist/killer;BAK1;ortholog
7.06    BARX1      NM_021570                                    transcription factor
                               Homeobox protein BarH-like 1;BARX1;ortholog activity;transcription factor act
-2.47   BARX2      NM_003658                                    transcription factor
                               Homeobox protein BarH-like 2;BARX2;ortholog activity;transcription factor act
-3.09   BAX        NM_004324                                    receptor
                               Apoptosis regulator BAX;BAX;ortholog binding
-2.95   BBS7       NM_018190   Bardet-Biedl syndrome 7 protein;BBS7;ortholog
-3.41   BCAN       NM_021948   Brevican core protein;BCAN;ortholog
2.12    BCHE       NM_000055   Cholinesterase;BCHE;orthologhydrolase activity, acting on ester bonds
-2.23   BCOR       NM_017745   BCL-6 corepressor;BCOR;ortholog
6.07    BDP1       NM_018429                                    translation factor activity, nucleic acid
                               Transcription factor TFIIIB component B'' homolog;BDP1;ortholog binding;tran
2.40    BET1       NM_005868   BET1 homolog;BET1;ortholog SNAP receptor activity
-2.87   BFAR       NM_016561   Bifunctional apoptosis regulator;BFAR;ortholog
2.67    BGN        NM_001711   Biglycan;BGN;ortholog            receptor activity
-3.20   BHC80      NM_016621                                    ubiquitin-protein ligase activity
                               PHD finger protein 21A;PHF21A;ortholog
-2.81   BICD2      NM_015250   Protein bicaudal D homolog 2;BICD2;ortholog
2.69    BIK        NM_001197   Bcl-2-interacting killer;BIK;ortholog
2.27    BIN1       NM_004305   Myc box-dependent-interacting protein 1;BIN1;ortholog
-2.39   BIN2       NM_016187   Bridging integrator 2;BIN2;ortholog
2.14    BIRC7      NM_022161                                    protein binding;peptidase inhibitor activity
                               Baculoviral IAP repeat-containing protein 7;BIRC7;ortholog
-2.63   BLP1       NM_078473   TM2 domain-containing protein 2;TM2D2;ortholog
-2.34   BLP2       NM_025141   TM2 domain-containing protein 3;TM2D3;ortholog
-2.26   BMPR2      NM_001204                                    transmembrane receptor protein
                               Bone morphogenetic protein receptor type-2;BMPR2;ortholog kinase activity;tr
-2.78   BNIP2      NM_004330   BCL2/adenovirus E1B 19 kDa protein-interacting protein 2;BNIP2;ortholog
2.64    BNIP3L     NM_004331   BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;BNIP3L;ortholog
2.06    BOK        NM_032515                                    receptor binding
                               Bcl-2-related ovarian killer protein;BOK;ortholog
-2.08   BOLA1      NM_016074   BolA-like protein 1;BOLA1;ortholog
-2.39   BPHL       NM_004332                                    serine-type peptidase activity
                               Valacyclovir hydrolase;BPHL;ortholog
-3.26   BRAP       NM_006768                                    ubiquitin-protein ligase activity
                               BRCA1-associated protein;BRAP;ortholog
3.58    BRCA1      NM_007294                                  transcription factor activity;transcription factor act
                               Breast cancer type 1 susceptibility protein;BRCA1;ortholog
-2.47   BRE        NM_004899   Protein BRE;BRE;ortholog
-2.40   BRI3BP     NM_080626   BRI3-binding protein;BRI3BP;ortholog
2.98    BRIP1      NM_032043                                  DNA helicase activity;nucleic acid binding
                               Fanconi anemia group J protein;BRIP1;ortholog
-2.49   BSCL2      NM_032667   Seipin;BSCL2;ortholog
-2.34   BSDC1      NM_018045   BSD domain-containing protein 1;BSDC1;ortholog
-2.13   BSG        NM_001728   Basigin;BSG;ortholog
2.81    BSPRY      NM_017688                                  ubiquitin-protein ligase activity
                               B box and SPRY domain-containing protein;BSPRY;ortholog
-2.30   BTAF1      NM_003972                                  DNA helicase activity;nucleic
                               TATA-binding protein-associated factor 172;BTAF1;ortholog acid binding
2.80    BTD        NM_000060   Biotinidase;BTD;ortholog       hydrolase activity
2.41    BTF3L4     XM_371577                                  transcription factor activity;transcription factor act
                               Transcription factor BTF3 homolog 4;BTF3L4;ortholog
3.16    BTNL2      NM_019602   Butyrophilin-like protein 2;BTNL2;ortholog
5.81    BUB1       NM_004336                                  protein kinase activity
                               Mitotic checkpoint serine/threonine-protein kinase BUB1;BUB1;ortholog
-2.68   BUCS1      NM_052956                                  ligase mitochondrial;ACSM1;ortholog
                               Acyl-coenzyme A synthetase ACSM1,activity
2.71    BZW1       NM_014670                                  nuclease activity;translation factor activity,
                               Basic leucine zipper and W2 domain-containing protein 1;BZW1;ortholog nucleic
-2.49   C10ORF129 NM_207321                                   ligase mitochondrial;ACSM6;ortholog
                               Acyl-coenzyme A synthetase ACSM6,activity
2.92    C10ORF140 NM_207371    Protein DLN-1;C10orf140;ortholog
3.18    C10ORF59   NM_018363   Renalase;C10orf59;ortholog
3.93    C10ORF94   NM_130784   Synaptonemal complex central element protein 1;SYCE1;ortholog
-3.18   C11ORF13   NM_003475   Ras association domain-containing protein 7;RASSF7;ortholog
3.00    C11ORF30   NM_020193   Protein EMSY;EMSY;ortholog
-2.47   C11ORF73   NM_016401   Uncharacterized protein C11orf73;C11orf73;ortholog
3.43               NM_017841
        C11ORF79,SDH5                                         protein binding
                               Protein EMI5 homolog, mitochondrial;C11orf79;ortholog
-1.95   C13ORF17   NM_018185   DCN1-like protein 2;DCUN1D2;ortholog
-2.44   C13ORF31   NM_153218   UPF0124 protein C13orf31;C13orf31;ortholog
2.64    C14ORF11   NM_018453   E2F-associated phosphoprotein;EAPP;ortholog
4.15    C14ORF115 NM_018228    Uncharacterized protein C14orf115;C14orf115;ortholog
2.57    C14ORF162 NM_020181    NM_020181.2 was permanently suppressed because currently there is support f
3.94    C14ORF2    NM_004894   6.8 kDa mitochondrial proteolipid;MP68;ortholog
4.05    C14ORF58   NM_017791                                    C receptor-related protein activity
                               Feline leukemia virus subgrouptransmembrane transporter2;FLVCR2;ortholog
-2.39   C15ORF24   NM_020154   UPF0480 protein C15orf24;C15orf24;ortholog
-2.19   C17ORF103 NM_152914    Protein GTLF3B;GTLF3B;ortholog
2.15    C17ORF38   XM_375404                                  protein binding;kinase regulator activity
                               Phosphoinositide 3-kinase regulatory subunit 6;PIK3R6;ortholog
-2.08   C17ORF39   NM_024052   Uncharacterized protein C17orf39;C17orf39;ortholog
2.59    C17ORF63   NM_018182   Uncharacterized protein C17orf63;C17orf63;ortholog
-2.46   C19ORF22   NM_138774   R3H domain-containing protein C19orf22;C19orf22;ortholog
-2.75   C19ORF32   NM_138393                                  receptor 6;REEP6;ortholog
                               Receptor expression-enhancing protein activity;transmembrane transporter activ
2.08    C19ORF77   XM_209196   Transmembrane protein HSPC323;YS019_HUMAN;ortholog
2.46    C1ORF114   NM_021179   Uncharacterized protein C1orf114;C1orf114;ortholog
3.06    C1ORF14    NM_030933   Uncharacterized protein C1orf14;C1orf14;ortholog
4.04    C1ORF159   NM_017891   Uncharacterized protein C1orf159;C1orf159;ortholog
2.42    C1ORF227   XM_086616   UPF0732 protein C1orf227
-3.24   C1ORF50    NM_024097   Uncharacterized protein C1orf50;C1orf50;ortholog
2.42    C1ORF56    NM_017860   Uncharacterized protein C1orf56;C1orf56;ortholog
-2.11   C1ORF57    NM_032324                                  kinase activity
                               Nucleoside-triphosphatase C1orf57;C1orf57;ortholog
2.37    C1ORF66    NM_015997                                  RNA methyltransferase activity;nucleic acid bindin
                               UPF0431 protein C1orf66;C1orf66;ortholog
7.01    C1S        NM_001734                                  serine-type peptidase activity
                               Complement C1s subcomponent light chain;C1S;ortholog
-2.17   C2         NM_000063                                  serine-type
                               Complement C2a fragment;C2;ortholog peptidase activity
3.41    C20ORF13   NM_017714                                  peptidase activity
                               Threonine aspartase subunit beta;TASP1;ortholog
-2.47   C20ORF135   NM_080622   Uncharacterized protein C20orf135;C20orf135;ortholog
-2.24   C20ORF151   NM_080833                                  transcription factor activity;transcription factor act
                                Uncharacterized protein C20orf151;C20orf151;ortholog
-2.26   C20ORF161   NM_033421   Sorting nexin-21;SNX21;ortholog
3.38    C20ORF177   NM_022106   Uncharacterized protein C20orf177;C20orf177;ortholog
-2.59   C20ORF19    NM_018474   Uncharacterized protein C20orf19;C20orf19;ortholog
2.89    C20ORF27    NM_017874   UPF0687 protein C20orf27;C20orf27;ortholog
-2.02   C20ORF36    NM_018257                                  methyltransferase activity
                                Protein-L-isoaspartate O-methyltransferase domain-containing protein 2;PCMTD
3.55    C20ORF43    NM_016407   UPF0549 protein C20orf43;C20orf43;ortholog
3.78    C20ORF54    NM_033409                                  G-protein coupled receptor activity
                                Uncharacterized protein C20orf54;C20orf54;ortholog
-2.37   C20ORF79    NM_178483   Uncharacterized protein C20orf79;C20orf79;ortholog
5.64    C21ORF42    NM_058184   Uncharacterized protein C21orf42;C21orf42;ortholog
3.18    C21ORF45    NM_018944   Protein Mis18-alpha;MIS18A;ortholog
-2.67   C21ORF67    NM_058189   Uncharacterized protein C21orf67;C21orf67;ortholog
-1.97   C21ORF81    NM_153750   Uncharacterized protein C21orf81;C21orf81;ortholog
2.80    C22ORF1     NM_001585                                  hydrolase activity
                                Metallophosphoesterase domain-containing protein 1;MPPED1;ortholog
3.74    C22ORF26    NM_018280   Putative uncharacterized protein C22orf26;C22orf26;ortholog
5.21    C22ORF34    NM_198851   Uncharacterized protein C22orf34;C22orf34;ortholog
4.07    C22ORF8     NM_017911   Protein FAM118A;FAM118A;ortholog
3.77    C2CD3       NM_015531   C2 domain-containing protein 3;C2CD3;ortholog
-2.26   C2orf12     BC069763                                   DNA replication origin 1;RBMS1;ortholog
                                RNA-binding motif, single-stranded-interacting proteinbinding;single-stranded DN
-3.74   C2ORF28     NM_016085   Apoptosis-related protein 3;APR3;ortholog
2.21    C2ORF29     NM_017546   Uncharacterized protein C2orf29;C2orf29;ortholog
-2.23   C2ORF30     NM_015701   XTP3-transactivated gene B protein;C2orf30;ortholog
-2.10   C2ORF79     XM_372919                                  phosphoprotein phosphatase activity;phosphopro
                                Uncharacterized protein C2orf79;C2orf79;ortholog
4.49    C2ORF81     XM_371503   Uncharacterized protein C2orf81;C2orf81;ortholog
-2.78   C3ORF1      NM_016589   Transmembrane protein C3orf1;C3orf1;ortholog
2.54    C3ORF36     NM_025041   Uncharacterized protein C3orf36;C3orf36;ortholog
-2.15   C3ORF64     NM_173654                                  transferase activity, transferring
                                Uncharacterized glycosyltransferase AER61;AER61;ortholog glycosyl groups
-2.90   C4ORF17     NM_032149   Uncharacterized protein C4orf17;C4orf17;ortholog
3.69    C4ORF21     NM_018392   Uncharacterized protein C4orf21;C4orf21;ortholog
2.36    C5ORF14     NM_024715   Thioredoxin domain-containing protein 15;TXNDC15;ortholog
-2.44   C5ORF45     NM_016175   UPF0544 protein C5orf45;C5orf45;ortholog
-2.97   C5ORF51     NM_175921   UPF0600 protein C5orf51;C5orf51;ortholog
-2.28   C5ORF6      NM_016605   Protein FAM53C;FAM53C;ortholog
-2.55   C6ORF115    XM_371848   Uncharacterized protein C6orf115;C6orf115;ortholog
2.85    C6ORF70     XM_376556   Transmembrane protein C6orf70;C6orf70;ortholog
2.19    C6ORF96     NM_017909   Required for meiotic nuclear division protein 1 homolog;RMND1;ortholog
2.86    C7ORF16     NM_006658   G-substrate;GSBS;ortholog
4.38    C7ORF42     NM_017994   UPF0458 protein C7orf42;C7orf42;ortholog
-1.95   C7ORF62     NM_152706   Uncharacterized protein C7orf62;C7orf62;ortholog
2.92    C9ORF156    NM_016481   Nef-associated protein 1;C9orf156;ortholog
3.54    C9ORF158    NM_031219                                  hydrolase activity
                                Haloacid dehalogenase-like hydrolase domain-containing protein 3;HDHD3;ortho
2.92    C9ORF16     NM_024112   UPF0184 protein C9orf16;C9orf16;ortholog
2.47    C9orf165    NM_198573   Uncharacterized protein C9orf165;C9orf165;ortholog
3.00    C9ORF36     NM_015667   Protein FAM75A1;FAM75A1;ortholog
-2.16   C9ORF39     NM_017738   Centlein;CNTLN;ortholog
-2.44   C9ORF4      XM_378078   Uncharacterized protein C9orf4;C9orf4;ortholog
-1.99   C9ORF59     NM_033387   Protein FAM78A;FAM78A;ortholog
-2.44   C9ORF74     NM_030914   Ubiquitin-related modifier 1 homolog;URM1;ortholog
-2.11   C9ORF81    XM_095991   Centrosomal protein of 78 kDa;CEP78;ortholog
-2.19   C9ORF87    NM_018112   Trimeric intracellular cation channel type B;TMEM38B;ortholog
-2.46   CABLES1    NM_138375   CDK5 and ABL1 enzyme substrate 1;CABLES1;ortholog
-2.38   CABP5      NM_019855                                    calcium ion
                               Calcium-binding protein 5;CABP5;ortholog binding;calmodulin binding
-2.53   CACNA1A    NM_000068                                    voltage-gated subunit alpha-1A;CACNA1A;ortho
                               Voltage-dependent P/Q-type calcium channelcalcium channel activity;voltage-ga
-2.62   CACNA1C    NM_000719                                    voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent L-type calcium channel subunit alpha-1C;CACNA1C;ortholog
3.75    CACNA1H    NM_021098                                    voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent T-type calcium channel subunit alpha-1H;CACNA1H;ortholog
-2.07   CACNA1I    NM_021096                                    voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent T-type calcium channel subunit alpha-1I;CACNA1I;ortholog
2.69    CACNA2D3   NM_018398                                    voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent calcium channel subunit delta-3;CACNA2D3;ortholog
3.04    CACNG6     NM_145814   Voltage-dependent calcium channel gamma-6 subunit;CACNG6;ortholog
2.85    CACNG7     NM_031896                                    voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent calcium channel gamma-7 subunit;CACNG7;ortholog
3.57    CAMK2G     NM_001222                                     protein kinase type II
                               Calcium/calmodulin-dependentprotein kinase activity gamma chain;CAMK2G;ort
2.70    CAMP       NM_004345                                    protein binding;peptidase inhibitor activity
                               Antibacterial protein LL-37;CAMP;ortholog
3.23    CAPZB      NM_004930                                     beta;CAPZB;ortholog
                               F-actin-capping protein subunitstructural constituent of cytoskeleton;actin binding
-2.87   CARD11     NM_032415   Caspase recruitment domain-containing protein 11;CARD11;ortholog
2.72    CARD6      NM_032587   Caspase recruitment domain-containing protein 6;CARD6;ortholog
5.61    CARKD      NM_018210   Carbohydrate kinase domain-containing protein;CARKD;ortholog
-2.21   CART       NM_004291   CART(42-89);CARTPT;ortholog
2.57    CASP4      NM_001225                                    cysteine-type peptidase activity
                               Caspase-4 subunit 2;CASP4;ortholog
3.84    CAST       NM_015576   Calpastatin;CAST;ortholog        protein binding;cysteine-type endopeptidase inhib
-2.46   CBR1       NM_001757                                    oxidoreductase
                               Carbonyl reductase [NADPH] 1;CBR1;ortholog activity
2.71    CBX8       NM_020649                                    nucleic acid binding;chromatin binding
                               Chromobox protein homolog 8;CBX8;ortholog
-2.41   CCDC114    NM_144577   Coiled-coil domain-containing protein 114;CCDC114;ortholog
-2.62   CCDC121    NM_024584   Coiled-coil domain-containing protein 121;CCDC121;ortholog
-2.08   CCDC128    NM_152994   Coiled-coil domain-containing protein 128;CCDC128;ortholog
2.93    CCDC132    NM_024553   Coiled-coil domain-containing protein 132;CCDC132;ortholog
2.88    CCDC151    NM_145045   Coiled-coil domain-containing protein 151;CCDC151;ortholog
-2.00   CCDC6      NM_005436   Coiled-coil domain-containing protein 6;CCDC6;ortholog
-2.20   CCDC60     NM_178499   Coiled-coil domain-containing protein 60;CCDC60;ortholog
2.59    CCDC74A    NM_138770   Coiled-coil domain-containing protein 74A;CCDC74A;ortholog
4.03    CCDC87     NM_018219   Coiled-coil domain-containing protein 87;CCDC87;ortholog
-1.97   CCDC96     NM_153376   Coiled-coil domain-containing protein 96;CCDC96;ortholog
-2.22   CCKAR      NM_000730                                    G-protein coupled
                               Cholecystokinin receptor type A;CCKAR;ortholog receptor activity
2.11    CCL21      NM_002989                                    chemokine
                               C-C motif chemokine 21;CCL21;ortholog activity
-2.14   CCL22      NM_002990   MDC(7-69);CCL22;ortholog chemokine activity
-2.41   CCL28      NM_019846                                    chemokine
                               C-C motif chemokine 28;CCL28;ortholog activity
3.46    CCNB3      NM_033031                                    protein binding;kinase activator activity;kinase reg
                               G2/mitotic-specific cyclin-B3;CCNB3;ortholog
2.15    CCNG1      NM_004060   Cyclin-G1;CCNG1;ortholog         protein binding;kinase activator activity;kinase reg
-2.76   CCNI       NM_006835   Cyclin-I;CCNI;ortholog           protein binding;kinase activator activity;kinase reg
2.52    CCNJ       NM_019084   Cyclin-J;CCNJ;ortholog           protein binding;kinase activator activity;kinase reg
-2.53   CCNT1      NM_001240   Cyclin-T1;CCNT1;ortholog         transcription factor activity;protein binding;kinase
2.31    CD1A       NM_001763                                    receptor activity
                               T-cell surface glycoprotein CD1a;CD1A;ortholog
-2.00   CD24       NM_013230   Signal transducer CD24;CD24;ortholog
-2.95   CD5L       NM_005894   CD5 antigen-like;CD5L;ortholog   receptor activity
-2.27   CD68       NM_001251   Macrosialin;CD68;ortholog
-2.32   CD79A      NM_001783                                    receptor activity
                               B-cell antigen receptor complex-associated protein alpha-chain;CD79A;ortholog
2.30    CD84       NM_003874                                    receptor
                               SLAM family member 5;CD84;ortholog activity;receptor binding
2.20    CDC10      NM_001788   Septin-7;SEPT7;ortholog          GTPase activity;structural constituent of cytoskele
-3.00   CDC23      NM_004661                                    ubiquitin-protein ligase activity
                               Cell division cycle protein 23 homolog;CDC23;ortholog
-3.27   CDC25B    NM_004358                                     2;CDC25B;ortholog
                              M-phase inducer phosphatase phosphoprotein phosphatase activity;phosphopro
-2.32   CDC25C    NM_001790                                     3;CDC25C;ortholog
                              M-phase inducer phosphatase phosphoprotein phosphatase activity;phosphopro
-3.19   CDC27     NM_001256   Cell division cycle protein 27 homolog;CDC27;ortholog
-2.50   CDC37     NM_007065                                     protein binding;kinase activator activity;kinase reg
                              Hsp90 co-chaperone Cdc37;CDC37;ortholog
-2.80   CDC42     NM_001791                                     GTPase activity;protein binding
                              Cell division control protein 42 homolog;CDC42;ortholog
2.54    CDC45L    NM_003504                                     DNA replication origin binding
                              CDC45-related protein;CDC45L;ortholog
2.53    CDCA4     NM_017955                                     transcription factor activity;transcription factor act
                              Cell division cycle-associated protein 4;CDCA4;ortholog
-2.24   CDCA5     NM_080668   Sororin;CDCA5;ortholog
2.51    CDH19     NM_021153   Cadherin-19;CDH19;ortholog calcium ion binding
-2.18   CDH2      NM_001792   Cadherin-2;CDH2;ortholog          calcium ion binding
2.73    CDH23     NM_022124   Cadherin-23;CDH23;ortholog calcium ion binding
-2.08   CDK11A    NM_024011                                       kinase 6;CDC2L2;ortholog
                              Cell division cycle 2-like proteinprotein kinase activity
2.18    CDK8      NM_001260                                     protein kinase
                              Cell division protein kinase 8;CDK8;ortholog activity
-3.23   CDKN2A    NM_000077   Cyclin-dependent kinase inhibitor 2A, isoform 4;CDKN2A;ortholog
-2.73   CEBPE     NM_001805                                     transcription factor activity;transcription factor act
                              CCAAT/enhancer-binding protein epsilon;CEBPE;ortholog
2.78    CEND1     NM_016564   Cell cycle exit and neuronal differentiation protein 1;CEND1;ortholog
2.37    CENTA2    NM_018404                                     nucleic
                              Centaurin-alpha-2;CENTA2;ortholog acid binding;protein binding;small GTPas
-2.28   CES2      NM_003869   Carboxylesterase 2;CES2;ortholog  hydrolase activity, acting on ester bonds
-3.63   CES4      NM_016280                                     hydrolase activity, acting on ester bonds
                              Inactive carboxylesterase 4;CES4;ortholog
3.18    CFB       NM_001710                                     serine-type peptidase activity
                              Complement factor B Bb fragment;CFB;ortholog
2.96    CFL1      NM_005507   Cofilin-1;CFL1;ortholog           structural constituent of cytoskeleton;actin binding
-2.13   CGB1      NM_033377                                     hormone 1;CGB1;ortholog
                              Choriogonadotropin subunit beta variant activity
3.63    CHCHD3    NM_017812   Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial;CHC
2.72    CHEK1     NM_001274                                     protein kinase activity
                              Serine/threonine-protein kinase Chk1;CHEK1;ortholog
6.75    CHKA      NM_001277                                     kinase
                              Choline kinase alpha;CHKA;ortholog activity
4.20    CHRAC1    NM_017444                                     DNA-directed DNA polymerase
                              Chromatin accessibility complex protein 1;CHRAC1;ortholog activity;transcripti
-2.36   CHRDL1    NM_145234                                     receptor
                              Chordin-like protein 1;CHRDL1;orthologbinding
-2.41   CHST11    NM_018413                                     11;CHST11;ortholog
                              Carbohydrate sulfotransferase transferase activity
2.56    CIAO1     NM_004804   Protein CIAO1;CIAO1;ortholog
-2.35   CIAPIN1   NM_020313   Anamorsin;CIAPIN1;ortholog
2.24    CIB1      NM_006384                                     kinase activity;phosphoprotein phosphatase activ
                              Calcium and integrin-binding protein 1;CIB1;ortholog
-3.69   CIDEC     NM_022094   Cell death activator CIDE-3;CIDEC;ortholog
-2.25   CIG5      NM_080657   Radical S-adenosyl methionine domain-containing protein 2;RSAD2;ortholog
-2.03   CLCF1     NM_013246                                     hematopoietin/interferon-class (D200-domain) cy
                              Cardiotrophin-like cytokine factor 1;CLCF1;ortholog
-3.05   CLCN5     NM_000084                                     anion channel
                              Chloride channel protein 5;CLCN5;ortholog activity
2.49    CLDN1     NM_021101   Claudin-1;CLDN1;ortholog
2.68    CLDN10    NM_006984   Claudin-10;CLDN10;ortholog
2.39    CLDN12    NM_012129   Claudin-12;CLDN12;ortholog
2.62    CLDN17    NM_012131   Claudin-17;CLDN17;ortholog
2.96    CLECSF2   NM_005127                                     receptor activity;receptor binding
                              C-type lectin domain family 2 member B;CLEC2B;ortholog
-3.17   CLN3      NM_000086   Battenin;CLN3;ortholog
-3.82   CLPP      NM_006012                                     serine-type peptidase activity
                              Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial;CLPP;o
11.10   CMPK1     NM_016308   UMP-CMP kinase;CMPK1;ortholog     nucleotide kinase activity
-2.32   CNGA1     NM_000087                                     receptor activity;voltage-gated potassium channe
                              cGMP-gated cation channel alpha-1;CNGA1;ortholog
-2.15   CNNM2     NM_017649   Metal transporter CNNM2;CNNM2;ortholog
-2.80   CNTN5     NM_014361   Contactin-5;CNTN5;ortholog phosphoprotein phosphatase activity;phosphopro
2.98    COL17A1   NM_000494                                     extracellular matrix structural constituent
                              97 kDa linear IgA disease antigen;COL17A1;ortholog
-2.89   COL1A1    NM_000088                                     extracellular
                              Collagen alpha-1(I) chain;COL1A1;ortholog matrix structural constituent
-2.17   COL4A1    NM_001845   Collagen alpha-1(IV) chain;COL4A1;ortholog
-2.55   COL4A2     NM_001846   Canstatin;COL4A2;ortholog extracellular matrix structural constituent
-2.29   COL4A3     NM_000091   Tumstatin;COL4A3;ortholog
-2.09   COL4A5     NM_000495   Collagen alpha-5(IV) chain;COL4A5;ortholog
-2.75   COL4A6     NM_001847                                    extracellular matrix structural constituent
                               Collagen alpha-6(IV) chain;COL4A6;ortholog
-3.03   COL6A1     NM_001848                                    extracellular matrix structural constituent
                               Collagen alpha-1(VI) chain;COL6A1;ortholog
-2.19   COL6A2     NM_001849                                    extracellular matrix structural constituent
                               Collagen alpha-2(VI) chain;COL6A2;ortholog
2.22    COL9A2     NM_001852                                    extracellular matrix structural constituent
                               Collagen alpha-2(IX) chain;COL9A2;ortholog
-2.88   COLQ       NM_005677                                      tail peptide;COLQ;ortholog
                               Acetylcholinesterase collagenicextracellular matrix structural constituent
7.48    COMT       NM_000754                                    methyltransferase
                               Catechol O-methyltransferase;COMT;ortholog activity
2.35    COPS4      NM_016129   COP9 signalosome complex subunit 4;COPS4;ortholog
4.05    COQ4       NM_016035   Ubiquinone biosynthesis protein COQ4 homolog;COQ4;ortholog
-2.48   CORO1B     NM_020441   Coronin-1B;CORO1B;ortholog structural constituent of cytoskeleton;actin binding
-2.19   CORO7      NM_024535   Coronin-7;CORO7;ortholog         structural constituent of cytoskeleton;actin binding
-2.12   CPA1       NM_001868   Carboxypeptidase A1;CPA1;orthologmetallopeptidase activity
3.54    CPB2       NM_001872   Carboxypeptidase B2;CPB2;orthologmetallopeptidase activity
-3.26   CPN1       NM_001308                                    metallopeptidase activity
                               Carboxypeptidase N catalytic chain;CPN1;ortholog
-2.36   CPN2       J05158                                       receptor activity
                               Carboxypeptidase N subunit 2;CPN2;ortholog
-2.72   CPSF3      NM_016207                                    endoribonuclease activity;poly(A) RNA binding
                               Cleavage and polyadenylation specificity factor subunit 3;CPSF3;ortholog
2.48    CPT1A      NM_001876                                    acetyltransferase activity
                               Carnitine O-palmitoyltransferase 1, liver isoform;CPT1A;ortholog
-2.52   CRAT       NM_000755                                    acetyltransferase activity
                               Carnitine O-acetyltransferase;CRAT;ortholog
1.99    CRB1       NM_012076   Crumbs homolog 1;CRB1;ortholog
5.31    CREG       NM_003851   Protein CREG1;CREG1;ortholog
3.18    CRI1       NM_014335   EP300-interacting inhibitor of differentiation 1;EID1;ortholog
2.02    CRIP1      NM_001311                                    structural
                               Cysteine-rich protein 1;CRIP1;ortholog constituent of cytoskeleton
-3.10   CRK        NM_005206   Proto-oncogene C-crk;CRK;ortholog
2.47    CRTAC1     NM_018058                                    calcium ion binding;calmodulin binding;calcium-d
                               Cartilage acidic protein 1;CRTAC1;ortholog
2.15    CRYAA      NM_000394                                    structural molecule activity
                               Alpha-crystallin A chain, short form;CRYAA;ortholog
-3.33   CRYGA      NM_014617   Gamma-crystallin A;CRYGA;orthologstructural molecule activity
2.44    CRYGD      NM_006891                                    structural
                               Gamma-crystallin D;CRYGD;ortholog molecule activity
2.68    CRYZL1     NM_005111                                    oxidoreductase activity
                               Quinone oxidoreductase-like protein 1;CRYZL1;ortholog
-2.51   CSEN       NM_013434   Calsenilin;KCNIP3;ortholog       calcium ion binding
3.02    CSGLCA-T   NM_019015                                    transferase activity, transferring
                               Chondroitin sulfate glucuronyltransferase;CSGLCAT;ortholog glycosyl groups
3.26    CSMD2      NM_052896   CUB and sushi domain-containing protein 2;CSMD2;ortholog
3.96    CSRP3      NM_003476                                    structural constituent
                               Cysteine and glycine-rich protein 3;CSRP3;ortholog of cytoskeleton
-2.21   CST7       NM_003650   Cystatin-F;CST7;ortholog         protein binding;cysteine-type endopeptidase inhib
2.51    CSTP1      NM_018340   Uncharacterized metallophosphoesterase CSTP1;CSTP1;ortholog
6.09    CTCF       NM_006565                                    transcription factor
                               Transcriptional repressor CTCF;CTCF;ortholog activity;transcription factor act
-2.28   CTNNA1     NM_001903   Catenin alpha-1;CTNNA1;ortholog  structural constituent of cytoskeleton;actin binding
-3.56   CTNND1     NM_001331   Catenin delta-1;CTNND1;ortholog  structural constituent of cytoskeleton;intermediate
-2.73   CTPS       NM_001905   CTP synthase 1;CTPS;ortholog     ligase activity
4.30    CTPS2      NM_019857   CTP synthase 2;CTPS2;ortholog    ligase activity
-2.80   CTSF       NM_003793   Cathepsin F;CTSF;ortholog cysteine-type peptidase activity
3.25    CTTN       NM_005231                                    structural
                               Src substrate cortactin;CTTN;ortholog constituent of cytoskeleton;actin binding
7.26    CUL9       NM_015089   p53-associated parkin-like cytoplasmic protein;PARC;ortholog
-2.28   CUZD1      NM_022034                                    oxidoreductase activity;serine-type peptidase
                               CUB and zona pellucida-like domain-containing protein 1;CUZD1;ortholog acti
2.23    CXORF27    XM_048235   Huntingtin-interacting protein M;CXorf27;ortholog
-2.76   CXXC4      NM_025212   CXXC-type zinc finger protein 4;CXXC4;ortholog
-2.31   CYFIP1     NM_014608                                             binding;small GTPase regulator activity
                               Cytoplasmic FMR1-interacting protein 1;CYFIP1;ortholog
-2.40   CYLD       NM_015247                                    structural constituent of ribosome;nucleic acid bin
                               Probable ubiquitin carboxyl-terminal hydrolase CYLD;CYLD;ortholog
2.18    CYP11B2     NM_000498 Cytochrome P450 11B2, mitochondrial;CYP11B2;ortholog
                                                               oxidoreductase activity
3.92    CYP21A2     NM_000500 Cytochrome P450 21;CYP21A2;ortholog
                                                               oxidoreductase activity
2.04    CYP27A1     NM_000784 Cytochrome P450 27, mitochondrial;CYP27A1;ortholog
                                                               oxidoreductase activity
-2.85   CYP27B1     NM_000785 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;CYP27B1;ortholog
                                                               oxidoreductase activity
3.44    CYP2A6      NM_000762 Cytochrome P450 2A6;CYP2A6;ortholog
                                                               oxidoreductase activity
2.76    CYT19       NM_020682 Arsenite methyltransferase;AS3MT;ortholog
                                                               methyltransferase activity
3.33                NM_021006 LD78-beta(5-70);CCL3L3;ortholog
        D17S1718,SCYA3L1                                       chemokine activity
-2.37   DAB2        NM_001343 Disabled homolog 2;DAB2;ortholog receptor binding
2.65    DAF         NM_000574 Complement decay-accelerating factor;CD55;ortholog
7.08    DALRD3      NM_018114 DALR anticodon-binding domain-containing protein 3;DALRD3;ortholog
                                                               aminoacyl-tRNA ligase activity
2.76    DAP13       NM_018838 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;NDUFA12;o
                                                               oxidoreductase activity
2.03    DAZ4        NM_020420 Deleted in azoospermia proteinRNA binding
                                                                4;DAZ4;ortholog
2.16    DAZAP1      NM_018959 DAZ-associated protein 1;DAZAP1;ortholog
                                                               RNA binding
3.00    DAZAP2      NM_014764 DAZ-associated protein 2;DAZAP2;ortholog
2.49    DBX2        NM_001004329Homeobox protein DBX2;DBX2;ortholog
                                                               transcription factor activity;transcription factor act
-2.87   DCHS1       NM_003737 Protocadherin-16;DCHS1;ortholog  calcium ion binding
6.10    DCLK2                                                  protein kinase activity;structural constituent of cyt
                    NM_152619 Serine/threonine-protein kinase DCLK2;DCLK2;ortholog
-2.82   DCLRE1B     NM_022836 DNA cross-link repair 1B protein;DCLRE1B;ortholog
2.11    DCPS        NM_014026 Scavenger mRNA-decapping enzyme DcpS;DCPS;ortholog
                                                               hydrolase activity
2.31    DCTN5       NM_032486 Dynactin subunit 5;DCTN5;orthologmicrotubule motor activity;structural constituent o
3.33    DDA3        NM_032636 Proline/serine-rich coiled-coil protein 1;PSRC1;ortholog
-4.05   DDC         NM_000790 Aromatic-L-amino-acid decarboxylase;DDC;ortholog
                                                               carboxy-lyase activity
3.29    DDEF2       NM_003887 Development and differentiation-enhancing binding;protein binding;small GTPas
                                                               nucleic acid factor 2;DDEF2;ortholog
3.14    DDX20       NM_007204 Probable ATP-dependent RNARNA helicase activity;translation factor activity, nu
                                                                helicase DDX20;DDX20;ortholog
4.68    DDX25       NM_013264 ATP-dependent RNA helicase DDX25;DDX25;ortholog
                                                               RNA helicase activity;nucleic acid binding
-2.82   DDX26       NM_012141 Integrator complex subunit 6;INTS6;ortholog activity;nucleic acid binding
                                                               RNA helicase
2.52    DDX31       NM_022779 Probable ATP-dependent RNARNA helicase activity;nucleic acid binding
                                                                helicase DDX31;DDX31;ortholog
2.15    DDX3X                                                  RNA helicase activity;nucleic acid binding
                    NM_001356 ATP-dependent RNA helicase DDX3X;DDX3X;ortholog
6.41    DDX6        NM_004397 Probable ATP-dependent RNARNA helicase activity;nucleic acid binding
                                                                helicase DDX6;DDX6;ortholog
2.47    DDX60       NM_017631 Probable ATP-dependent RNADNA helicase activity;hydrolase activity;nucleic ac
                                                                helicase DDX60;DDX60;ortholog
-2.67   DECR2       NM_020664 Peroxisomal 2,4-dienoyl-CoA reductase;DECR2;ortholog
                                                               oxidoreductase activity
2.74    DEF8        NM_207514 Differentially expressed in FDCP 8 homolog;DEF8;ortholog
-2.82   DEPDC1B     NM_018369 DEP domain-containing proteinnucleic acid binding
                                                                1B;DEPDC1B;ortholog
2.41    DEPDC2      NM_024870 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2GTPase reg
                                                               receptor activity;protein binding;small protein;PR
2.37    DERA        NM_015954 Putative deoxyribose-phosphate aldolase;DERA;ortholog
                                                               lyase activity
3.89    DES         NM_001927 Desmin;DES;ortholog              structural constituent of cytoskeleton
2.52    DGKD                                                   kinase activity
                    NM_003648 Diacylglycerol kinase delta;DGKD;ortholog
-2.78   DHCR7       NM_001360 7-dehydrocholesterol reductase;DHCR7;ortholog
                                                               oxidoreductase activity;receptor activity
-3.80   DHFRP1      NM_000791 Dihydrofolate reductase;DHFRP1;ortholog
                                                               oxidoreductase activity
-2.36   DHH         NM_021044 Desert hedgehog protein C-product;DHH;ortholog
                                                               peptidase activity;receptor binding
2.65    DHRS1       NM_138452 Dehydrogenase/reductase SDR family member 1;DHRS1;ortholog
                                                               oxidoreductase activity
-2.33   DIRC2       NM_032839 Disrupted in renal carcinoma protein 2;DIRC2;ortholog
                                                               transmembrane transporter activity
-2.38   DISC1       NM_018662 Disrupted in schizophrenia 1 protein;DISC1;ortholog
-2.40               A
        DKFZP564I1171 L117555   cDNA DKFZp564I1171
4.44                XM_376189 This record was removed as a result of standard genome annotation processing
        DKFZP586K1520
4.05    DLG4        NM_001365 Disks large homolog 4;DLG4;ortholog
-3.11   DLST        NM_001933 Dihydrolipoyllysine-residue succinyltransferase activity
                                                               acyltransferase component of 2-oxoglutarate deh
-2.62   DLX6        XM_376652 Homeobox protein DLX-6;DLX6;ortholog factor activity;transcription factor act
                                                               transcription
3.71    DMC1        NM_007068 Meiotic recombination protein DMC1/LIM15 homolog;DMC1;ortholog activity;s
                                                               hydrolase activity;DNA strand annealing
-2.64   DMGDH     NM_013391                                     oxidoreductase activity
                              Dimethylglycine dehydrogenase, mitochondrial;DMGDH;ortholog
-2.34   DMKN      NM_033317   Dermokine;DMKN;ortholog
3.98    DMRT3     NM_021240                                      transcription factor
                              Doublesex- and mab-3-related nucleic acid binding3;DMRT3;ortholog
2.49    DMRTA2    XM_027162                                      transcription factor
                              Doublesex- and mab-3-related nucleic acid bindingA2;DMRTA2;ortholog
4.01    DMTF1     NM_021145                                     transcription factor activity;transcription factor act
                              Cyclin-D-binding Myb-like transcription factor 1;DMTF1;ortholog
-2.25   DNAH17    NM_173628                                     microtubule motor activity;hydrolase activity;struc
                              Dynein heavy chain 17, axonemal;DNAH17;ortholog
2.83    DNAH7     NM_018897                                     microtubule motor
                              Dynein heavy chain 7, axonemal;DNAH7;ortholog activity;hydrolase activity;struc
2.53    DNAJB12   NM_017626   DnaJ homolog subfamily B member 12;DNAJB12;ortholog
3.85    DND1      NM_194249                                     RNA binding
                              Dead end protein homolog 1;DND1;ortholog
3.07    DNM3      NM_015569   Dynamin-3;DNM3;ortholog           GTPase activity;structural constituent of cytoskele
2.21    DNMT2     NM_004412                                     DNA-methyltransferase activity;nucleic acid bindi
                              tRNA (cytosine-5-)-methyltransferase;TRDMT1;ortholog
-2.49   DNMT3A    NM_022552                                     DNA-methyltransferase activity;nucleic acid bindi
                              DNA (cytosine-5)-methyltransferase 3A;DNMT3A;ortholog
4.44    DNTT      NM_004088                                     DNA-directed DNA polymerase activity;nucleic ac
                              DNA nucleotidylexotransferase;DNTT;ortholog
5.19    DOCK10    XM_371595                                     protein binding;small GTPase regulator activity;gu
                              Dedicator of cytokinesis protein 10;DOCK10;ortholog
-2.18   DOCK9     NM_015296                                     protein binding;small
                              Dedicator of cytokinesis protein 9;DOCK9;ortholog GTPase regulator activity;gu
-2.25   DOLPP1    NM_020438                                     hydrolase activity
                              Dolichyldiphosphatase 1;DOLPP1;ortholog
-2.78   DPEP1     NM_004413   Dipeptidase 1;DPEP1;ortholog metallopeptidase activity
-3.05   DPYS      NM_001385   Dihydropyrimidinase;DPYS;ortholog hydrolase activity
3.34    DUOX2     NM_014080                                     o
                              Dual oxidase 2;DUOX2;orthologxidoreductase activity
-2.67   DUSP15    NM_080611                                     phosphoprotein phosphatase
                              Dual specificity protein phosphatase 15;DUSP15;ortholog activity;phosphopro
-2.29   DUSP28    XM_209509                                     phosphoprotein phosphatase activity;phosphopro
                              Dual specificity phosphatase 28;DUSP28;ortholog
-2.05   DUSP3     NM_004090                                     phosphoprotein phosphatase activity;phosphopro
                              Dual specificity protein phosphatase 3;DUSP3;ortholog
-3.60   DUSP9     NM_001395                                     phosphoprotein phosphatase activity;phosphopro
                              Dual specificity protein phosphatase 9;DUSP9;ortholog
-2.72   DVL2      NM_004422                                     receptor binding;enzyme regulator activity
                              Segment polarity protein dishevelled homolog DVL-2;DVL2;ortholog
-3.21   DVL3      NM_004423                                     receptor binding;enzyme regulator activity
                              Segment polarity protein dishevelled homolog DVL-3;DVL3;ortholog
-2.51   DYDC2     NM_032372   DPY30 domain-containing protein 2;DYDC2;ortholog
2.00    DYRK1A    NM_001396                                     non-membrane spanning protein tyrosine kinase
                              Dual specificity tyrosine-phosphorylation-regulated kinase 1A;DYRK1A;ortholog
-2.56   E2F2      NM_004091                                     transcription factor activity;transcription factor act
                              Transcription factor E2F2;E2F2;ortholog
2.25    ECM2      NM_001393   Extracellular matrix protein 2;ECM2;ortholog
2.43    EDEM1     XM_376201                                     hydrolase activity
                              ER degradation-enhancing alpha-mannosidase-like 1;EDEM1;ortholog
6.12    EDEM2     NM_018217   ER degradation-enhancing alpha-mannosidase-like 2;EDEM2;ortholog
                                                                hydrolase activity
2.68    EDN1      NM_001955   Big endothelin-1;EDN1;ortholog    hormone activity
-2.13   EED       NM_003797   Polycomb protein EED;EED;ortholog transcription factor activity;transcription factor act
-2.17   EFNB1     NM_004429   Ephrin-B1;EFNB1;ortholog          receptor binding
-2.35   EGFL8     NM_030652                                     calcium ion binding
                              EGF-like domain-containing protein 8;EGFL8;ortholog
-2.41   EGR2      NM_000399                                     transcription factor
                              Early growth response protein 2;EGR2;ortholog activity;transcription factor act
-2.54   EHD2      NM_014601                                     calcium ion binding;protein binding;small GTPase
                              EH domain-containing protein 2;EHD2;ortholog
7.01    EHMT2     NM_006709   Histone-lysine N-methyltransferase, H3 lysine-9 specific 3;EHMT2;ortholog
3.27    EIF2C2    NM_012154                                     factor 2C factor activity, nucleic acid binding;tran
                              Eukaryotic translation initiation translation2;EIF2C2;ortholog
2.62    EIF4G3    NM_003760                                     factor 4 gamma activity, nucleic acid
                              Eukaryotic translation initiation translation factor3;EIF4G3;ortholog binding;tran
-2.04   EKI1      NM_018638                                     kinase activity
                              Ethanolamine kinase 1;ETNK1;ortholog
-2.77   ELAC2     NM_018127                                     protein 2;ELAC2;ortholog
                              Zinc phosphodiesterase ELAC hydrolase activity
2.14    ELAVL2    NM_004432                                     RNA binding
                              ELAV-like protein 2;ELAVL2;ortholog
-3.01   ELAVL4    NM_021952                                     RNA binding
                              ELAV-like protein 4;ELAVL4;ortholog
-2.51   ELF4      NM_001421                                       Elf-4;ELF4;ortholog
                              ETS-related transcription factortranscription factor activity;receptor binding;transc
-2.21   ELMO1     NM_014800                                     receptor binding
                              Engulfment and cell motility protein 1;ELMO1;ortholog
3.08    ELMOD3    NM_032213                                     receptor binding
                              ELMO domain-containing protein 3;ELMOD3;ortholog
-2.77   ELOVL3    NM_152310                                     acyltransferase 3;ELOVL3;ortholog
                              Elongation of very long chain fatty acids proteinactivity
-2.84   ELYS      NM_015446                                     transcription factor activity;transcription factor act
                              AT-hook-containing transcription factor 1;AHCTF1;ortholog
-2.48   EML3       NM_153265   Echinoderm microtubule-associated protein-like 3;EML3;ortholog
-2.19   ENGASE     NM_022759                                    hydrolase activity;deaminase activity
                               Cytosolic endo-beta-N-acetylglucosaminidase;ENASE_HUMAN;ortholog
3.27    ENOSF1     NM_017512   Mitochondrial enolase superfamily member 1;ENOSF1;ortholog
                                                                racemase and epimerase activity
3.84    ENPP1      NM_006208                                    pyrophosphatase activity;nucleotide phosphatase
                               Nucleotide pyrophosphatase;ENPP1;ortholog
-2.99   ENPP5      NM_021572                                    pyrophosphatase activity;nucleotide phosphatase
                               Ectonucleotide pyrophosphatase/phosphodiesterase family member 5;ENPP5;o
-2.41   EPC1       NM_025209                                    nucleic acid binding;chromatin binding
                               Enhancer of polycomb homolog 1;EPC1;ortholog
-2.26   EPS15      NM_001981                                    calcium ion 15;EPS15;ortholog
                               Epidermal growth factor receptor substrate binding;protein binding;small GTPase
-2.56   ERCC1      NM_001983                                    endodeoxyribonuclease
                               DNA excision repair protein ERCC-1;ERCC1;ortholog activity;nucleic acid bindi
-2.19   ERCC4      NM_005236                                    endodeoxyribonuclease activity;nucleic acid bindi
                               DNA repair endonuclease XPF;ERCC4;ortholog
2.92    ERCC5      NM_000123                                    exodeoxyribonuclease activity;endodeoxyribonuc
                               DNA repair protein complementing XP-G cells;ERCC5;ortholog
-2.20   ERO1L      NM_014584                                    oxidoreductase activity
                               ERO1-like protein alpha;ERO1L;ortholog
3.08    ERO1LB     NM_019891                                    oxidoreductase activity
                               ERO1-like protein beta;ERO1LB;ortholog
6.75    ERP70      NM_004911                                    protein disulfide
                               Protein disulfide-isomerase A4;PDIA4;ortholog isomerase activity
-2.46   ESR1       NM_000125   Estrogen receptor;ESR1;ortholog  ligand-dependent nuclear receptor activity;transcr
3.67    ETAA16     NM_019002   Ewing's tumor-associated antigen 1;ETAA1;ortholog
-1.97   ETFDH      NM_004453                                    oxidoreductase activity
                               Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial;ETFDH;
3.06    EXOSC3     NM_016042                                    exoribonuclease activity;nucleic acid binding
                               Exosome complex exonuclease RRP40;EXOSC3;ortholog
2.30    EXOSC7     NM_015004                                    exoribonuclease activity;nucleic acid binding
                               Exosome complex exonuclease RRP42;EXOSC7;ortholog
3.04    EXT2       NM_000401   Exostosin-2;EXT2;ortholog        transferase activity, transferring glycosyl groups
-3.58   EXTL2      NM_001439                                    transferase
                               Processed exostosin-like 2;EXTL2;orthologactivity, transferring glycosyl groups
2.24    EYA1       NM_000503                                    phosphatase activity;phosphatase activity
                               Eyes absent homolog 1;EYA1;ortholog
-2.00   EYA3       NM_001990                                    phosphatase activity;phosphatase activity
                               Eyes absent homolog 3;EYA3;ortholog
3.88    EYA4       NM_004100                                    phosphatase activity;phosphatase activity
                               Eyes absent homolog 4;EYA4;ortholog
-2.76   FAAH       NM_001441                                    transferase activity;hydrolase activity;ligase activi
                               Fatty-acid amide hydrolase 1;FAAH;ortholog
3.64    FABP2      NM_000134                                    lipid binding
                               Fatty acid-binding protein, intestinal;FABP2;ortholog
-2.85   FAHD2A     NM_016044                                    hydrolase activity
                               Fumarylacetoacetate hydrolase domain-containing protein 2A;FAHD2A;ortholog
-2.74   FALZ       NM_004459                                     subunit BPTF;BPTF;ortholog
                               Nucleosome-remodeling factoracetyltransferase activity;nucleic acid binding;chr
-2.25   FAM10A6    XM_051271   This RefSeq was permanently suppressed because it is now thought that this ps
2.46    FAM134B    NM_019000   Protein FAM134B;FAM134B;ortholog
2.53    FAM160A2   NM_032127   UPF0518 protein FAM160A2;FAM160A2;ortholog
3.63    FAM164B    XM_087800                                    transcription factor
                               UPF0418 protein FAM164B;FAM164B;ortholog activity;transcription factor act
-2.35   FAM18B     NM_016078   Protein FAM18B;FAM18B;ortholog
3.91    FAM21B     XM_290482   Protein FAM21B;FAM21B;ortholog
2.94    FAM45B     NM_018472   This RefSeq was permanently suppressed because it is now thought that this ge
-2.19   FAM46A     NM_017633   Protein FAM46A;FAM46A;ortholog
-2.59   FAM49A     NM_030797   Protein FAM49A;FAM49A;ortholog
2.64    FAM64A     NM_019013   Protein FAM64A;FAM64A;ortholog
-3.58   FAM69B     NM_152421   Protein FAM69B;FAM69B;ortholog
2.47    FAM74A4    NM_207507   Protein FAM74A4;FAM74A4;ortholog
-2.39   FAM83D     NM_030919   Protein FAM83D;FAM83D;ortholog
-2.31   FAM86B1    NM_032916   Protein FAM86B1;FAM86B1;ortholog
2.83    FAM8A1     NM_016255   Protein FAM8A1;FAM8A1;ortholog
-2.25   FAM90A1    NM_018088   Protein FAM90A1;FAM90A1;ortholog
-3.18   FANCI      NM_018193   Fanconi anemia group I protein;FANCI;ortholog
2.64    FANCL      NM_018062                                    ubiquitin-protein ligase
                               E3 ubiquitin-protein ligase FANCL;FANCL;ortholog activity
3.48    FARSLA     NM_004461                                    alpha chain;FARSA;ortholog
                               Phenylalanyl-tRNA synthetase aminoacyl-tRNA ligase activity
3.68    FASN       NM_004104                                    oxidoreductase activity;methyltransferase activity
                               Oleoyl-[acyl-carrier-protein] hydrolase;FASN;ortholog
3.31    FBLN1      NM_001996   Fibulin-1;FBLN1;ortholog         extracellular matrix structural constituent;calcium
-3.23   FBN3       NM_032447   Fibrillin-3;FBN3;ortholog        extracellular matrix structural constituent;calcium
2.89    FBP2       NM_003837 Fructose-1,6-bisphosphatase isozyme 2;FBP2;ortholog activity;carbohydrate p
                                                              carbohydrate phosphatase
-2.13   FBS1       NM_022452 Probable fibrosin-1 long transcript protein;FBRS;ortholog
-2.29   FBXL10     NM_032590 JmjC domain-containing histone demethylation protein 1B;FBXL10;ortholog
3.97    FBXL19     XM_375337 F-box/LRR-repeat protein 19;FBXL19;ortholog
-2.62   FBXL5      NM_012161 F-box/LRR-repeat protein 5;FBXL5;ortholog
3.66    FBXO11     NM_012167 F-box only protein 11;FBXO11;ortholog
                                                              ubiquitin-protein ligase activity
4.43    FBXO2      NM_012168 F-box only protein 2;FBXO2;ortholog
-2.08   FBXO23     NM_130465 Tetraspanin-17;TSPAN17;ortholog  receptor binding
-2.00   FBXO3      NM_012175 F-box only protein 3;FBXO3;ortholog activity
                                                              ligase
3.56    FBXO40     NM_016298 F-box only protein 40;FBXO40;ortholog
-2.41   FBXO6      NM_018438 F-box only protein 6;FBXO6;ortholog
-2.41   FBXW9      NM_032301 F-box/WD repeat-containing protein 9;FBXW9;ortholog
-2.86   FCRLA      NM_032738 Fc receptor-like A;FCRLA;orthologreceptor activity
-2.28   FEM1A      NM_018708 Protein fem-1 homolog A;FEM1A;ortholog
3.94    FEZF1                                                 transcription factor
                   XM_371948 Fez family zinc finger protein 1;FEZF1;ortholog activity;transcription factor act
3.46    FGD6                                                  protein binding;small GTPase regulator
                   XM_370702 FYVE, RhoGEF and PH domain-containing protein 6;FGD6;ortholog activity;gu
-2.52   FGFR1                                                 transmembrane receptor
                   NM_000604 Basic fibroblast growth factor receptor 1;FGFR1;orthologprotein kinase activity;tr
7.74    FGFR1OP    NM_007045 FGFR1 oncogene partner;FGFR1OP;ortholog
-2.17   FGFRL1     NM_021923 Fibroblast growth factor receptor-like 1;FGFRL1;orthologprotein kinase activity;tr
                                                              transmembrane receptor
-2.05   FGIF       NM_017704 Ankyrin repeat domain-containing protein 49;ANKRD49;ortholog
-2.29   FIGN       NM_018086 Fidgetin;FIGN;ortholog           hydrolase activity
-2.25   FIP1L1     NM_030917 Pre-mRNA 3'-end-processing factor FIP1;FIP1L1;ortholog
-2.63   FKBP11     NM_016594 FK506-binding protein 11;FKBP11;ortholog
                                                              isomerase activity;calcium ion binding
-2.89   FKSG43     NM_032033 Putative FERM domain-containing protein FKSG43;FKS43_HUMAN;ortholog
2.43    FLJ10246   NM_018038 This record was removed by RefSeq staff.
3.72    FLJ11292   NM_018382 NM_018382.1 was permanently suppressed because it appears to represent ex
-2.13   FLJ14959   XM_371139 This record was removed as a result of standard genome annotation processing
2.32    FLJ40092   NM_207494 This record was removed by RefSeq staff.
-2.28   FLJ40852   NM_173677 NM_173677.1 was permanently suppressed because currently there is support f
-2.34   FLJ41200   XM_379623 uncharacterized LOC401492 (FLJ41200), non-coding RNA
3.71    FLJ41327   NM_207485 NM_207485.1 was permanently suppressed because currently there is insufficie
3.46    FLJ42200   NM_207471 This record was removed by RefSeq staff.
2.31    FLJ42289   NM_207383 NM_207383.2 was permanently suppressed because currently there is support f
2.78    FLJ43860   NM_207414 uncharacterized protein LOC389690
3.21    FLJ45983   NM_207423 NM_207423.1: This RefSeq was permanently suppressed because currently the
-1.99   FLYWCH1    NM_032296 FLYWCH-type zinc finger-containing protein 1;FLYWCH1;ortholog
3.10    FMO1       NM_002021 Dimethylaniline monooxygenase [N-oxide-forming] 1;FMO1;ortholog
                                                              oxidoreductase activity
-4.05   FMO5       NM_001461 Dimethylaniline monooxygenase [N-oxide-forming] 5;FMO5;ortholog
                                                              oxidoreductase activity
-2.23   FMR1       NM_002024 Fragile X mental retardation 1 protein;FMR1;ortholog
                                                              RNA binding
2.03    FNTA       NM_002027 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha;FNTA
                                                              acyltransferase activity
4.35    FOXA1      NM_004496 Hepatocyte nuclear factor 3-alpha;FOXA1;ortholog
                                                              transcription factor activity;transcription factor act
-2.39   FOXD1      NM_004472 Forkhead box protein D1;FOXD1;ortholog factor activity;transcription factor act
                                                              transcription
4.78    FOXF2      NM_001452 Forkhead box protein F2;FOXF2;ortholog factor activity;transcription factor act
                                                              transcription
-2.26   FOXG1C     X74144                                     transcription
                               Forkhead box protein G1;FOXG1;ortholog factor activity;transcription factor act
2.56    FOXL2      NM_023067 Forkhead box protein L2;FOXL2;ortholog factor activity;transcription factor act
                                                              transcription
-2.36   FOXP2      NM_014491 Forkhead box protein P2;FOXP2;ortholog factor activity;transcription factor act
                                                              transcription
6.06    FOXRED1    NM_017547 FAD-dependent oxidoreductase domain-containing protein 1;FOXRED1;ortholog
                                                              oxidoreductase activity
2.39    FRG2       NM_001005217Protein FRG2;FRG2;ortholog
-3.18   FRMD7      NM_194277 FERM domain-containing protein 7;FRMD7;ortholog
-2.12   FRMD8        NM_031904   FERM domain-containing protein 8;FRMD8;ortholog
-2.31   FUCA1        NM_000147                                     hydrolase activity, hydrolyzing N-glycosyl compou
                                 Tissue alpha-L-fucosidase;FUCA1;ortholog
-4.11   FURIN        NM_002569   Furin;FURIN;ortholog              serine-type peptidase activity
2.47    FVT1         NM_002035                                     oxidoreductase activity
                                 3-ketodihydrosphingosine reductase;KDSR;ortholog
-3.88   FXYD2        NM_001680                                     cation transmembrane transporter activity
                                 Sodium/potassium-transporting ATPase gamma chain;FXYD2;ortholog
2.66    G3BP2        NM_012297                                     RNA binding;receptor binding
                                 Ras GTPase-activating protein-binding protein 2;G3BP2;ortholog
-2.24   GAB3         NM_080612   GRB2-associated-binding protein 3;GAB3;ortholog
2.19    GABARAP      NM_007278                                     structural constituent of cytoskeleton;microtubule
                                 Gamma-aminobutyric acid receptor-associated protein;GABARAP;ortholog
-2.02   GABRB3       NM_000814                                     GABA receptor activity;ligand-gated ion
                                 Gamma-aminobutyric acid receptor subunit beta-3;GABRB3;ortholog channel a
2.88    GABRP        NM_014211                                     GABA receptor activity;ligand-gated ion channel a
                                 Gamma-aminobutyric acid receptor subunit pi;GABRP;ortholog
3.02    GADD45B      NM_015675   Growth arrest and DNA-damage-inducible protein GADD45 beta;GADD45B;orth
-2.26   GADD45GIP1   NM_052850   Growth arrest and DNA-damage-inducible proteins-interacting protein 1;GADD4
-1.99   GALE         NM_000403                                     hydro-lyase
                                 UDP-glucose 4-epimerase;GALE;ortholog activity;racemase and epimerase act
-2.59   GALGT        NM_001478   Beta-1,4 N-acetylgalactosaminyltransferase 1;B4GALNT1;ortholog
2.72    GALNACT-2    NM_018590                                     transferase activity, transferring glycosyl groups
                                 Chondroitin sulfate N-acetylgalactosaminyltransferase 2;CSGALNACT2;ortholog
-2.14   GALNT10      NM_017540                                     transferase activity, transferring glycosyl
                                 Polypeptide N-acetylgalactosaminyltransferase 10;GALNT10;ortholog groups
-3.05   GALR1        NM_001480                                     G-protein
                                 Galanin receptor type 1;GALR1;ortholog coupled receptor activity
3.81    GAP43        NM_002045   Neuromodulin;GAP43;ortholog
2.08    GAPT         NM_152687   Uncharacterized protein C5orf29;C5orf29;ortholog
5.70    GAS1         NM_002048   Growth arrest-specific protein 1;GAS1;ortholog
-2.02   GASP2        NM_138437                                     protein binding;serine-type endopeptidase inhibito
                                 WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1;WFIK
4.36    GATA5        NM_080473                                     nuclease activity;transcription factor activity;trans
                                 Transcription factor GATA-5;GATA5;ortholog
2.08    GBP4         NM_052941                                     GTPase activity;protein binding
                                 Guanylate-binding protein 4;GBP4;ortholog
-2.73   GBP5         NM_052942                                     GTPase activity;protein binding
                                 Guanylate-binding protein 5;GBP5;ortholog
2.22    GDAP2        NM_017686   Ganglioside-induced differentiation-associated protein 2;GDAP2;ortholog
-2.35   GDF9         NM_005260                                     growth factor activity
                                 Growth/differentiation factor 9;GDF9;ortholog
-2.96   GDI1         NM_001493                                      alpha;GDI1;ortholog
                                 Rab GDP dissociation inhibitor acyltransferase activity;protein binding;small GTP
-2.04   GDPD2        NM_017711                                     phosphoric domain-containing protein 2;GDPD2
                                 Glycerophosphodiester phosphodiesterasediester hydrolase activity;ligase activit
-2.77   GFI1B        NM_004188                                     transcription
                                 Zinc finger protein Gfi-1b;GFI1B;ortholog factor activity;transcription factor act
2.83    GHRL         NM_016362   Obestatin;GHRL;ortholog           hormone activity
3.17    GJB3         NM_024009                                     gap junction
                                 Gap junction beta-3 protein;GJB3;ortholog channel activity
-2.80   GJB6         NM_006783                                     gap junction
                                 Gap junction beta-6 protein;GJB6;ortholog channel activity
2.84    GKN1         NM_019617   Gastrokine-1;GKN1;ortholog
-2.07   GLRA2        NM_002063                                     receptor activity;ligand-gated ion channel activity
                                 Glycine receptor subunit alpha-2;GLRA2;ortholog
2.55    GLT8D1       NM_018446   Glycosyltransferase 8 domain-containing protein 1;GLT8D1;ortholog
-2.79   GLT8D2       NM_031302   Glycosyltransferase 8 domain-containing protein 2;GLT8D2;ortholog
5.72    GMEB1        NM_006582   Glucocorticoid modulatory element-binding protein 1;GMEB1;ortholog
2.79    GP1BB        NM_000407   Platelet glycoprotein Ib beta chain;GP1BB;ortholog
-2.35   GPD1         NM_005276                                     oxidoreductase cytoplasmic;GPD1;ortholog
                                 Glycerol-3-phosphate dehydrogenase [NAD+], activity
2.86    GPN2         NM_018066   GPN-loop GTPase 2;GPN2;ortholog acid binding
                                                                   nucleic
7.24    GPR114       NM_153837                                     G-protein coupled receptor activity
                                 Probable G-protein coupled receptor 114;GPR114;ortholog
3.06    GPR158       NM_020752   Probable G-protein coupled receptor 158;GPR158;ortholog
2.30    GRIA1        NM_000827                                     glutamate receptor activity;ligand-gated ion chann
                                 Glutamate receptor 1;GRIA1;ortholog
-3.19   GRIK4        NM_014619                                      kainate 4;GRIK4;ortholog
                                 Glutamate receptor, ionotropic glutamate receptor activity;ligand-gated ion chann
3.90    GRIN3A       NM_133445                                     glutamate receptor activity;ligand-gated ion chann
                                 Glutamate [NMDA] receptor subunit 3A;GRIN3A;ortholog
2.54    GRINL1A      NM_015532   Protein GRINL1A;GRINL1A;ortholog
6.46    GSDML        NM_018530   Gasdermin-B;GSDMB;ortholog
3.66    GSPT2        NM_018094                                     translation factor activity, nucleic acid binding;tran
                                 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B;GSPT2;orth
2.78    GTF2A1L      NM_006872                                     transcription factor activity;transcription factor act
                                 Transcription initiation factor IIA subunit 1-like;GTF2A1L;ortholog
-2.20   GTF2F1      NM_002096                                    subunit 1;GTF2F1;ortholog
                                General transcription factor IIF transcription factor activity;transcription factor act
2.35    GUCA1C      NM_005459                                    calcium ion binding;calmodulin binding;small GTP
                                Guanylyl cyclase-activating protein 3;GUCA1C;ortholog
-2.57   HAMP        NM_021175   Hepcidin-20;HAMP;ortholog
2.47    HAND1       NM_004821                                    transcription factor activity;transcription factor act
                                Heart- and neural crest derivatives-expressed protein 1;HAND1;ortholog
-2.34   HAPLN2      NM_021817   Hyaluronan and proteoglycan link protein 2;HAPLN2;ortholog
4.07    HBA2        NM_000517   Hemoglobin subunit alpha;HBA2;ortholog
-2.61   HBB         NM_000518   Hemoglobin subunit delta;HBD;ortholog
-2.35   HCA127      NM_018684   Hepatocellular carcinoma-associated antigen 127;HCA127;ortholog
-2.08   HDAC6       NM_006044                                    deacetylase activity;nucleic acid binding
                                Histone deacetylase 6;HDAC6;ortholog
2.78    HDAC7       NM_015401   Histone deacetylase 7;HDAC7;ortholog
                                                                 deacetylase activity;nucleic acid binding
3.33    HEBP1       NM_015987   Heme-binding protein 1;HEBP1;ortholog
2.87    HEMGN       NM_018437   Hemogen;HEMGN;ortholog
3.10    HEMK        NM_016173                                    methyltransferase activity
                                HemK methyltransferase family member 1;HEMK1;ortholog
-2.99   HERC3       NM_014606                                    ubiquitin-protein ligase activity
                                Probable E3 ubiquitin-protein ligase HERC3;HERC3;ortholog
3.61    HERPUD2     NM_022373   Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain
3.15    HEY1        NM_012258                                    transcription factor activity;transcription factor act
                                Hairy/enhancer-of-split related with YRPW motif protein 1;HEY1;ortholog
2.73    HEYL        NM_014571                                    transcription factor activity;transcription factor
                                Hairy/enhancer-of-split related with YRPW motif-like protein;HEYL;ortholog act
2.48    HIGD1B      NM_016438   HIG1 domain family member 1B;HIGD1B;ortholog
4.04    HINT1       NM_005340                                    nucleotide phosphatase activity;nucleotide phosp
                                Histidine triad nucleotide-binding protein 1;HINT1;ortholog
4.55    HIST1H2AJ   NM_021066                                    DNA binding
                                Histone H2A type 1-J;HIST1H2AJ;ortholog
1.99    HIST1H3I    NM_003533   Histone H3.1;HIST1H3J;ortholog
4.03    HKR3        NM_005341                                    transcription factor activity;transcription
                                Zinc finger and BTB domain-containing protein 48;ZBTB48;ortholog factor act
-2.04   HLA-C       NM_002117   HLA class I histocompatibility antigen, Cw-7 alpha chain;HLA-C;ortholog
-3.22   HLA-DRB1    NM_002124   HLA class II histocompatibility antigen, DRB1-1 beta chain;HLA-DRB1;ortholog
3.75    HLX1        NM_021958                                    transcription
                                H2.0-like homeobox protein;HLX;ortholog factor activity;transcription factor act
3.09    HLXB9       NM_005515                                    transcription factor activity;transcription factor act
                                Motor neuron and pancreas homeobox protein 1;MNX1;ortholog
3.15    HMG1L10     NM_172363   High mobility group protein 1-like 10;HMG1L10;ortholog
2.29    HMGB3       NM_005342   High mobility group protein B3;HMGB3;ortholog
2.48    HN1         NM_016185   Hematological and neurological expressed 1 protein;HN1;ortholog
3.32    HNF1A       NM_000545                                    transcription factor activity;transcription factor act
                                Hepatocyte nuclear factor 1-alpha;HNF1A;ortholog
-2.07   HNRPH1      NM_005520                                    structural constituent of ribosome;nucleic acid bin
                                Heterogeneous nuclear ribonucleoprotein H;HNRNPH1;ortholog
1.96    HOMER2      NM_004839                                    receptor binding
                                Homer protein homolog 2;HOMER2;ortholog
3.54    HOXA13      NM_000522                                    transcription factor activity;transcription factor act
                                Homeobox protein Hox-A13;HOXA13;ortholog
-2.61   HOXB1       NM_002144                                    transcription
                                Homeobox protein Hox-B1;HOXB1;orthologfactor activity;transcription factor act
-2.11   HOXB13      NM_006361                                    transcription factor activity;transcription factor act
                                Homeobox protein Hox-B13;HOXB13;ortholog
-2.03   HOXC13      NM_017410                                    transcription factor activity;transcription factor act
                                Homeobox protein Hox-C13;HOXC13;ortholog
4.57    HP1BP3      NM_016287   Heterochromatin protein 1-binding protein 3;HP1BP3;ortholog
2.30    HPCAL1      NM_002149                                    calcium ion binding;calmodulin binding
                                Hippocalcin-like protein 1;HPCAL1;ortholog
-2.20   HRG1        NM_017842   Heme transporter HRG1;Hrg1;ortholog
2.76    HRSP12      NM_005836   Ribonuclease UK114;HRSP12;ortholog
-2.45   HSPA2       NM_021979   Heat shock-related 70 kDa protein 2;HSPA2;ortholog
3.54    HSPC009     NM_014019   This record was removed by RefSeq staff; the sequence does not appear to rep
-2.49   HSYN        NM_018157   Synembryn-B;RIC8B;ortholog
-2.04   HTATSF1     NM_014500                                    RNA splicing
                                HIV Tat-specific factor 1;HTATSF1;ortholog factor activity, transesterification me
2.64    HYDIN       NM_017558   Hydrocephalus-inducing protein homolog;HYDIN2;ortholog
3.02    IAPP        NM_000415                                    hormone
                                Islet amyloid polypeptide;IAPP;ortholog activity
2.23    IBSP        NM_004967   Bone sialoprotein 2;IBSP;orthologextracellular matrix structural constituent
2.52    ID4         NM_001546                                    transcription factor activity;transcription factor act
                                DNA-binding protein inhibitor ID-4;ID4;ortholog
2.53    IDN3        NM_015384                                    nucleic
                                Nipped-B-like protein;NIPBL;ortholog acid binding;chromatin binding
2.03    IFFO1       NM_080730   Intermediate filament family orphan 1;IFFO1;ortholog
-1.97   IFI44       NM_006417   Interferon-induced protein 44;IFI44;ortholog
2.02    IFNA2       NM_000605   Interferon alpha-2;IFNA2;ortholog hematopoietin/interferon-class (D200-domain) cy
2.30    IFNA4       NM_021068   Interferon alpha-4;IFNA4;ortholog hematopoietin/interferon-class (D200-domain) cy
2.51    IFNAR2      NM_000874                                     interferon receptor activity
                                Interferon-alpha/beta receptor beta chain;IFNAR2;ortholog
5.73    IFNB1       NM_002176   Interferon beta;IFNB1;ortholog hematopoietin/interferon-class (D200-domain) cy
2.69    IFNG        NM_000619   Interferon gamma;IFNG;ortholog    hematopoietin/interferon-class (D200-domain) cy
2.49    IFT20       NM_174887   Intraflagellar transport protein 20 homolog;IFT20;ortholog
-2.02   IGBP1       NM_001551   Immunoglobulin-binding protein 1;IGBP1;ortholog
2.87    IGFBP7      NM_001553   Insulin-like growth factor-binding protein 7;IGFBP7;ortholog
2.81    IGHG4       BC025985                                      antigen binding
                                Ig gamma-4 chain C region;IGHG4;ortholog
-2.21   IL13RA1     NM_001560                                      chain;IL13RA1;ortholog
                                Interleukin-13 receptor alpha-1 cytokine receptor activity
-2.88   IL1F9       NM_019618                                     hematopoietin/interferon-class (D200-domain) cy
                                Interleukin-1 family member 9;IL1F9;ortholog
2.32    IL4         NM_000589   Interleukin-4;IL4;ortholog        hematopoietin/interferon-class (D200-domain) cy
-2.12   IL6R        NM_000565                                     cytokine receptor activity
                                Interleukin-6 receptor subunit alpha;IL6R;ortholog
3.12    IL9R        NM_002186                                     cytokine receptor activity
                                Interleukin-9 receptor;IL9R;ortholog
-2.05   ILT7        NM_012276                                      receptor subfamily A member 4;LILRA4;ortholog
                                Leukocyte immunoglobulin-likereceptor activity
-2.89   INF2        NM_032714   Inverted formin-2;INF2;ortholog   structural constituent of cytoskeleton;actin binding
2.33    INHBA       NM_002192                                     growth
                                Inhibin beta A chain;INHBA;ortholog factor activity
2.92    INPPL1      NM_001567   Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2;INPPL1;ortholog
-2.06   INSM1       NM_002196   Insulinoma-associated protein 1;INSM1;ortholog
4.22    INTS10      NM_018142   Integrator complex subunit 10;INTS10;ortholog
2.27    IQCC        NM_018134   IQ domain-containing protein C;IQCC;ortholog
-2.27   IREM2       NM_181449                                     receptor activity
                                CMRF35-like molecule 2;CD300E;ortholog
-2.08   IRF1        NM_002198                                     transcription
                                Interferon regulatory factor 1;IRF1;ortholog factor activity;transcription factor act
2.52    IRF3        NM_001571                                     transcription
                                Interferon regulatory factor 3;IRF3;ortholog factor activity;transcription factor act
-2.05   IRX4        NM_016358                                     transcription factor activity;transcription factor act
                                Iroquois-class homeodomain protein IRX-4;IRX4;ortholog
-2.66   ITCH        NM_031483                                      homolog;ITCH;ortholog
                                E3 ubiquitin-protein ligase Itchyubiquitin-protein ligase activity
-1.96   ITGA8       XM_167711   Integrin alpha-8 light chain;ITGA8;ortholog
-2.44   ITGAM       NM_000632   Integrin alpha-M;ITGAM;ortholog
2.48    IWS1        NM_017969   Protein IWS1 homolog;IWS1;ortholog
-2.40   IZUMO1      NM_182575   Izumo sperm-egg fusion protein 1;IZUMO1;ortholog
8.13    JMJD4       NM_023007   JmjC domain-containing protein 4;JMJD4;ortholog
                                                                  receptor activity
2.55    JMJD8       XM_290722                                     receptor activity
                                JmjC domain-containing protein 8;JMJD8;ortholog
-2.29   KA21,KRT222PNM_152349                                     structural constituent of cytoskeleton
                                Keratin-like protein KRT222;KRT222P;ortholog
-2.36   KBTBD7      NM_032138                                     structural protein 7;KBTBD7;ortholog
                                Kelch repeat and BTB domain-containingconstituent of cytoskeleton;actin binding
-2.48   KBTBD7      NM_032138                                     structural protein 7;KBTBD7;ortholog
                                Kelch repeat and BTB domain-containingconstituent of cytoskeleton;actin binding
-2.42   KCMF1       NM_020122   E3 ubiquitin-protein ligase KCMF1;KCMF1;ortholog
2.47    KCNC3       NM_004977                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily C member 3;KCNC3;ortholog
-3.63   KCNE1       NM_000219                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily E member 1;KCNE1;ortholog
2.44    KCNE1L      NM_012282                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily E member 1-like protein;KCNE1L;or
-2.06   KCNG1       NM_002237                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily G member 1;KCNG1;ortholog
4.32    KCNH6       NM_030779                                     receptor activity;voltage-gated potassium channe
                                Potassium voltage-gated channel subfamily H member 6;KCNH6;ortholog
2.53    KCNIP1      NM_014592                                     calcium ion binding;protein binding;small GTPase
                                Kv channel-interacting protein 1;KCNIP1;ortholog
-2.53   KCNJ2       NM_000891                                     voltage-gated potassium
                                Inward rectifier potassium channel 2;KCNJ2;ortholog channel activity;voltage-
2.07    KCNK10      NM_021161                                     voltage-gated potassium channel
                                Potassium channel subfamily K member 10;KCNK10;ortholog activity;voltage-
2.23    KCNK15      NM_022358                                     voltage-gated potassium channel
                                Potassium channel subfamily K member 15;KCNK15;ortholog activity;voltage-
3.97    KCNQ2       NM_004518                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily KQT member 2;KCNQ2;ortholog
2.71    KCNQ4       NM_004700                                     voltage-gated potassium channel activity;voltage-
                                Potassium voltage-gated channel subfamily KQT member 4;KCNQ4;ortholog
2.17    KCNS1      NM_002251                                    voltage-gated potassium channel activity;voltage-
                               Potassium voltage-gated channel subfamily S member 1;KCNS1;ortholog
2.25    KCTD15     NM_024076                                    protein binding
                               BTB/POZ domain-containing protein KCTD15;KCTD15;ortholog
2.87    KDELC1     NM_024089   KDEL motif-containing protein 1;KDELC1;ortholog
-2.68   KDELR3     NM_006855                                    receptor activity
                               ER lumen protein retaining receptor 3;KDELR3;ortholog
2.23    KIAA0179   XM_371417   Ribosomal RNA processing protein 1 homolog B;RRP1B;ortholog
-2.16   KIAA0643   NM_024793   Clusterin-associated protein 1;CLUAP1;ortholog
2.95    KIAA0676   NM_015043                                    protein binding;small
                               TBC1 domain family member 9B;TBC1D9B;orthologGTPase regulator activity
2.19    KIAA0774   XM_166270   Uncharacterized protein KIAA0774;KIAA0774;ortholog
2.74    KIAA1126   XM_050325                                    carbohydrate transmembrane transporter activity
                               Solute carrier family 45 member 4;SLC45A4;ortholog
2.43    KIAA1171   XM_370928                                    protein binding;small
                               TBC1 domain family member 24;TBC1D24;ortholog GTPase regulator activity
5.27    KIAA1194   NM_015455                                    exoribonuclease activity;nucleic
                               CCR4-NOT transcription complex subunit 6;CNOT6;ortholog acid binding
3.40    KIAA1199   NM_018689   Protein KIAA1199;KIAA1199;ortholog
6.78    KIAA1202   XM_050478                                    receptor
                               Protein Shroom4;SHROOM4;ortholog activity;ligand-gated ion channel activity
2.25    KIAA1210   XM_172801   Uncharacterized protein KIAA1210;KIAA1210;ortholog
3.22    KIAA1211   XM_044178   Uncharacterized protein KIAA1211;KIAA1211;ortholog
-2.30   KIAA1267   NM_015443   Uncharacterized protein KIAA1267;KIAA1267;ortholog
-2.25   KIAA1305   XM_370756                                    nucleic acid binding
                               Integrase catalytic domain-containing protein KIAA1305;KIAA1305;ortholog
3.29    KIAA1333   NM_017769                                    double-stranded DNA binding
                               G2/M phase-specific E3 ubiquitin-protein ligase;KIAA1333;ortholog
-2.14   KIAA1370   XM_035527   Uncharacterized protein KIAA1370;KIAA1370;ortholog
-2.19   KIAA1393   XM_375085                                    methyltransferase activity
                               tRNA (guanine-N(1)-)-methyltransferase;TRMT5;ortholog
-2.43   KIAA1429   NM_015496   Protein virilizer homolog;KIAA1429;ortholog
-2.41   KIAA1456   NM_182598   Putative methyltransferase KIAA1456;C8orf79;ortholog
2.73    KIAA1462   XM_166132   Uncharacterized protein KIAA1462;KIAA1462;ortholog
2.61    KIAA1468   NM_020854   LisH domain and HEAT repeat-containing protein KIAA1468;KIAA1468;ortholog
5.58    KIAA1579   XM_371258                                     2;RAVER2;ortholog
                               Ribonucleoprotein PTB-bindingRNA splicing factor activity, transesterification me
-2.70   KIAA1737   NM_033426   Uncharacterized protein KIAA1737;KIAA1737;ortholog
2.32    KIAA1786   XM_038436   Transmembrane protein 132B;TMEM132B;ortholog
-2.32   KIAA1853   XM_375000   Uncharacterized protein KIAA1853;KIAA1853;ortholog
2.91    KIAA1875   XM_291269   WD repeat-containing protein KIAA1875;KIAA1875;ortholog
5.60    KIAA1920   XM_375243   Uncharacterized protein KIAA1920;KIAA1920;ortholog
-2.64   KIAA1935   XM_087672                                    DNA-methyltransferase activity;nucleic acid bindi
                               PWWP domain-containing protein 2A;PWWP2A;ortholog
-2.52   KIAA1975   XM_370567                                     and PH domain-containing protein 11;AGAP11;o
                               Arf-GAP, GTPase, ANK repeatnucleic acid binding;protein binding;small GTPas
4.62    KIAA1991   XM_495886   RING finger protein 169;RNF169;ortholog
-3.26   KIAA2013   NM_138346   Uncharacterized protein KIAA2013;KIAA2013;ortholog
-3.03   KIF1B      NM_015074                                    microtubule
                               Kinesin-like protein KIF1B;KIF1B;ortholog motor activity;structural constituent o
-2.58   KIF26A     XM_050278                                    microtubule motor activity;structural constituent o
                               Kinesin-like protein KIF26A;KIF26A;ortholog
-2.54   KIF2B      NM_032559                                    microtubule
                               Kinesin-like protein KIF2B;KIF2B;ortholog motor activity;structural constituent o
-3.05   KIF3A      NM_007054                                    microtubule
                               Kinesin-like protein KIF3A;KIF3A;ortholog motor activity;structural constituent o
-2.49   KIF3C      NM_002254                                    microtubule
                               Kinesin-like protein KIF3C;KIF3C;ortholog motor activity;structural constituent o
6.03    KIFC3      NM_005550                                    microtubule
                               Kinesin-like protein KIFC3;KIFC3;ortholog motor activity;structural constituent o
-2.31   KIR2DL5    NM_020535                                    receptor activity
                               Killer cell immunoglobulin-like receptor 2DL5B;KIR2DL5B;ortholog
4.20    KKLC1      XM_117548   Kita-kyushu lung cancer antigen 1;KKLC1;ortholog
2.21    KL         NM_153683   Klotho peptide;KL;ortholog       glucosidase activity;hydrolase activity, hydrolyzing
2.71    KLC2       NM_022822                                    structural constituent of cytoskeleton
                               Kinesin light chain 2;KLC2;ortholog
2.78    KLF13      NM_015995                                    transcription factor activity;transcription factor act
                               Krueppel-like factor 13;KLF13;ortholog
-2.14   KLHL7      NM_018846                                    structural constituent of cytoskeleton;actin binding
                               Kelch-like protein 7;KLHL7;ortholog
2.15    KLRC1      NM_002259                                    receptor activity
                               NKG2-A/NKG2-B type II integral membrane protein;KLRC1;ortholog
-3.02   KNDC1      NM_033404                                    protein
                               Protein very KIND;KNDC1;ortholog binding;small GTPase regulator activity;gu
2.85    KRI1       NM_023008   Protein KRI1 homolog;KRI1;ortholog
-2.78   KRT10       NM_000421 Keratin, type I cytoskeletal 10;KRT10;ortholog
                                                               structural constituent of cytoskeleton
2.75    KRT23       NM_015515 Keratin, type I cytoskeletal 23;KRT23;ortholog
                                                               structural constituent of cytoskeleton
-3.23   KRT3        NM_057088 Keratin, type II cytoskeletal 3;KRT3;ortholog
                                                               structural constituent of cytoskeleton
-2.15   KRT40       NM_182497 Keratin, type I cytoskeletal 40;KRT40;ortholog
                                                               structural constituent of cytoskeleton
-2.15   KRT9        NM_000226 Keratin, type I cytoskeletal 9;KRT9;ortholog
                                                               structural constituent of cytoskeleton
7.99    KRTAP18-2                                              structural constituent of
                    NM_198693 Keratin-associated protein 10-2;KRTAP10-2;ortholog cytoskeleton
3.39    KRTAP19-1   NM_181607 Keratin-associated protein 19-1;KRTAP19-1;ortholog
-3.26   KRTAP4-5    NM_033188 Keratin-associated protein 4-5;KRTAP4-5;ortholog of cytoskeleton
                                                               structural constituent
2.18    KRTAP6-3    NM_181605 Keratin-associated protein 6-3;KRTAP6-3;ortholog
3.15    L3MBTL      NM_015478 Lethal(3)malignant brain tumor-like protein;L3MBTL;ortholog
                                                               transcription factor activity;chromatin binding;tran
10.63   LAK                                                    protein kinase activity
                    NM_025144 Alpha-protein kinase 1;ALPK1;ortholog
2.53    LAMB1       NM_002291 Laminin subunit beta-1;LAMB1;ortholog
2.72    LAPTM4B     NM_018407 Lysosomal-associated transmembrane protein 4B;LAPTM4B;ortholog
                                                               transmembrane transporter activity
3.68    LARP2       NM_018078 La-related protein 2;LARP2;ortholog
-2.20   LAS1L       NM_031206 LAS1-like protein;LAS1L;ortholog
4.47    LATS1                                                  protein kinase activity
                    NM_004690 Serine/threonine-protein kinase LATS1;LATS1;ortholog
2.99    LCE3D       NM_032563 Late cornified envelope proteinstructural molecule activity
                                                                3D;LCE3D;ortholog
3.08    LCK                                                    non-membrane spanning protein tyrosine kinase
                    NM_005356 Proto-oncogene tyrosine-protein kinase LCK;LCK;ortholog
2.53    LDHA        NM_005566 L-lactate dehydrogenase A chain;LDHA;ortholog
                                                               oxidoreductase activity
3.15    LEF1        NM_016269 Lymphoid enhancer-binding factor 1;LEF1;ortholog
                                                               nucleic acid binding
-2.36   LENEP       NM_018655 Lens epithelial cell protein LEP503;LENEP;ortholog
4.50    LGALS7      NM_002307 Galectin-7;LGALS7;ortholog
3.49    LIMA1       NM_016357 LIM domain and actin-binding protein 1;LIMA1;orthologcytoskeleton
                                                               structural constituent of
-2.40   LMNA        NM_170707 Lamin-A/C;LMNA;ortholog          structural constituent of cytoskeleton
4.09    LMO3        NM_001001395                               transcription
                                LIM domain only protein 3;LMO3;ortholog factor activity;transcription factor act
6.13    LMO4        NM_006769 LIM domain transcription factortranscription factor activity;transcription factor act
                                                                LMO4;LMO4;ortholog
-2.45   LNX         NM_032622 E3 ubiquitin-protein ligase LNX;LNX1;ortholog
                                                               structural constituent of cytoskeleton
-2.05   LOC115110   XM_378828 This record was removed as a result of standard genome annotation processing
2.48    LOC143244   XM_084467 This record was removed as a result of standard genome annotation processing
5.59    LOC146110   XM_018432 This record was removed as a result of standard genome annotation processing
3.04    LOC154323   XM_098512 This record was removed as a result of standard genome annotation processing
2.08    LOC163301   XM_088797 This record was removed as a result of standard genome annotation processing
-2.14   LOC196337   XM_113696 This record was removed as a result of standard genome annotation processing
2.27    LOC202227   XM_116396 This record was removed as a result of standard genome annotation processing
3.77    LOC255519   XM_171766 This record was removed as a result of standard genome annotation processing
-2.19   LOC256283   XM_173105 This record was removed as a result of standard genome annotation processing
-2.06   LOC283480   XM_378430 This record was removed as a result of standard genome annotation processing
-2.60   LOC284837   NM_194310 NM_194310.1 was permanently suppressed because it is a nonsense-mediated
3.33    LOC284901   XM_209408 This record was removed as a result of standard genome annotation processing
-2.54   LOC284933   XM_379064 This record was removed as a result of standard genome annotation processing
-3.06   LOC285189   XM_376111 This record was removed as a result of standard genome annotation processing
3.03    LOC285248   XM_211816 This record was removed as a result of standard genome annotation processing
3.41    LOC285307   XM_211837 This record was removed as a result of standard genome annotation processing
2.20    LOC285311   XM_209563 NM_001007534.1: This RefSeq was permanently suppressed because currently
-2.51   LOC285422   XM_379280 This record was removed as a result of standard genome annotation processing
-2.25   LOC285972   XM_379530 This record was removed as a result of standard genome annotation processing
2.92    LOC286561   XM_210515 This record was removed as a result of standard genome annotation processing
2.50    LOC339782   XM_295062 This record was removed as a result of standard genome annotation processing
3.08    LOC339903   XM_291063 This record was removed as a result of standard genome annotation processing
2.69    LOC340148   XM_295166   This record was removed as a result of standard genome annotation processing
2.27    LOC341604   XM_296315   This record was removed as a result of standard genome annotation processing
1.98    LOC342600   XM_292624   This record was removed as a result of standard genome annotation processing
3.23    LOC344382   XM_293026   This record was removed as a result of standard genome annotation processing
2.00    LOC345576   XM_293886   This record was removed as a result of standard genome annotation processing
2.04    LOC345711   XM_293937   This record was removed as a result of standard genome annotation processing
2.39    LOC347265   XM_294590   This record was removed by RefSeq staff.
2.75    LOC360030   XM_370669   This record was removed as a result of standard genome annotation processing
2.47    LOC387649   XM_373452   This record was removed as a result of standard genome annotation processing
2.20    LOC387771   XM_373500   This record was removed as a result of standard genome annotation processing
2.70    LOC387810   XM_373513   This record was removed as a result of standard genome annotation processing
2.31    LOC387820   XM_370665   This record was removed as a result of standard genome annotation processing
2.54    LOC388305   XM_373700   This record was removed as a result of standard genome annotation processing
2.91    LOC388365   XM_373723   This record was removed as a result of standard genome annotation processing
2.10    LOC388554   XM_371182   This record was removed as a result of standard genome annotation processing
-2.13   LOC388924   XM_373974   This record was removed as a result of standard genome annotation processing
-2.08   LOC388929   XM_371480   This record was removed as a result of standard genome annotation processing
2.00    LOC389150   XM_374052   This record was removed as a result of standard genome annotation processing
4.01    LOC389204   XM_374079   This record was removed as a result of standard genome annotation processing
2.64    LOC389330   XM_374139   This record was removed as a result of standard genome annotation processing
2.22    LOC389403   XM_374172   This record was removed as a result of standard genome annotation processing
2.56    LOC389405   XM_371829   This record was removed as a result of standard genome annotation processing
2.75    LOC389490   XM_371901   This record was removed as a result of standard genome annotation processing
4.16    LOC389526   XM_374222   This record was removed as a result of standard genome annotation processing
3.72    LOC389602   XM_372004   This record was removed as a result of standard genome annotation processing
2.14    LOC389656   XM_374268   This record was removed as a result of standard genome annotation processing
-2.05   LOC389657   XM_374269   This record was removed as a result of standard genome annotation processing
2.08    LOC389674   XM_372050   This record was removed as a result of standard genome annotation processing
4.94    LOC389702   XM_374289   This record was removed as a result of standard genome annotation processing
2.35    LOC389753   XM_372112   This record was removed as a result of standard genome annotation processing
3.14    LOC390233   XM_372424   This record was removed as a result of standard genome annotation processing
-3.66   LOC390256   XM_372432   This record was removed as a result of standard genome annotation processing
3.21    LOC390488   XM_372527   This record was removed as a result of standard genome annotation processing
3.76    LOC390547   XM_372553   This record was removed as a result of standard genome annotation processing
1.98    LOC391749   XM_373061   This record was removed as a result of standard genome annotation processing
14.60   LOC391769   XM_373079   This record was removed as a result of standard genome annotation processing
2.63    LOC392179   XM_373233   This record was removed as a result of standard genome annotation processing
2.73    LOC392238   XM_374372   This record was removed as a result of standard genome annotation processing
7.18    LOC392347   XM_373298   This record was removed as a result of standard genome annotation processing
2.12    LOC392395   XM_373319   NM_001013664.1: This RefSeq was temporarily suppressed because the CDS w
2.08    LOC392749   XM_374741   This record was removed as a result of standard genome annotation processing
-3.44   LOC399788   XM_374817   This record was removed as a result of standard genome annotation processing
4.25    LOC399937   XM_374917   This record was removed as a result of standard genome annotation processing
2.29    LOC400043   XM_378360   This record was removed as a result of standard genome annotation processing
2.13    LOC400214   XM_375081   This record was removed as a result of standard genome annotation processing
2.13    LOC400298   XM_375147   This record was removed as a result of standard genome annotation processing
2.50    LOC400552   XM_378623   This record was removed as a result of standard genome annotation processing
2.27    LOC400813   XM_378947   This record was removed as a result of standard genome annotation processing
2.91    LOC401014   XM_379141   This record was removed as a result of standard genome annotation processing
-2.10   LOC401015   XM_376148   This record was removed as a result of standard genome annotation processing
-2.51   LOC401016   XM_376150   This record was removed as a result of standard genome annotation processing
2.75    LOC401062   XM_379190   This record was removed as a result of standard genome annotation processing
-2.00   LOC401087   XM_376267   This record was removed as a result of standard genome annotation processing
-2.30   LOC401095   XM_376278   This record was removed as a result of standard genome annotation processing
2.40    LOC401180   XM_379325   uncharacterized LOC401180
3.03    LOC401207   XM_376423   This record was removed as a result of standard genome annotation processing
2.28    LOC401234   XM_379395   This record was removed as a result of standard genome annotation processing
2.51    LOC401252   XM_376488   NM_001013681.1 was permanently suppressed because currently there is insuf
2.82    LOC401254   XM_379406   This record was removed as a result of standard genome annotation processing
2.42    LOC401284   XM_379454   This record was removed as a result of standard genome annotation processing
2.84    LOC401352   XM_379493   This record was removed as a result of standard genome annotation processing
2.73    LOC401394   XM_379512   This record was removed as a result of standard genome annotation processing
2.71    LOC401434   XM_379531   This record was removed as a result of standard genome annotation processing
2.61    LOC401539   XM_379648   This record was removed as a result of standard genome annotation processing
2.27    LOC401543   XM_379656   This record was removed as a result of standard genome annotation processing
2.95    LOC401552   XM_379668   This record was removed as a result of standard genome annotation processing
2.22    LOC401983   XM_377630   This record was removed as a result of standard genome annotation processing
3.13    LOC402203   XM_377880   This record was removed as a result of standard genome annotation processing
4.91    LOC402245   XM_377926   This record was removed as a result of standard genome annotation processing
4.02    LOC402251   XM_377933   This record was removed as a result of standard genome annotation processing
-2.73   LOC402340   XM_378033   This record was removed as a result of standard genome annotation processing
2.66    LOC402455   XM_374713   This record was removed as a result of standard genome annotation processing
3.22    LOC402461   XM_379786   This record was removed as a result of standard genome annotation processing
2.67    LOC402490   XM_379820   This record was removed as a result of standard genome annotation processing
3.53    LOC402515   XM_380112   This record was removed as a result of standard genome annotation processing
2.91    LOC402516   XM_380113   This record was removed as a result of standard genome annotation processing
3.35    LOC402539   XM_379858   This record was removed as a result of standard genome annotation processing
3.03    LOC402596   XM_380146   This record was removed as a result of standard genome annotation processing
2.35    LOC402620   XM_379962   NM_001004302.2: This RefSeq was permanently suppressed because currently
2.76    LOC85028    XM_378848   This record was removed as a result of standard genome annotation processing
3.13    LOC91632    XM_039721   NM_001080422.1: This RefSeq was permanently suppressed because it is now
2.47    LOC92017    XM_042234   NM_001009607.1: This RefSeq was permanently suppressed because the CDS
-2.63   LOC93463    XM_376186   This record was removed as a result of standard genome annotation processing
-2.80   LPA         NM_005577   Apolipoprotein(a);LPA;orthologserine-type peptidase activity;calcium ion binding
2.24    LPXN        NM_004811   Leupaxin;LPXN;ortholog         structural constituent of cytoskeleton
-2.22   LRCH3       NM_032773   Leucine-rich repeat and calponin homology domain-containing protein 3;LRCH3
2.24    LRFN1       XM_290842                                  receptor III domain-containing protein 1;LRFN1;o
                                Leucine-rich repeat and fibronectin type activity
-2.33   LRP12       NM_013437                                  receptor protein
                                Low-density lipoprotein receptor-related activity 12;LRP12;ortholog
-2.78   LRP15       NM_052953                                  protein 3B;LRRC3B;ortholog
                                Leucine-rich repeat-containing receptor activity
3.08    LRP16       NM_014067   MACRO domain-containing protein 1;MACROD1;ortholog
3.85    LRP2BP      NM_018409                                  protein binding;enzyme regulator activity
                                LRP2-binding protein;LRP2BP;ortholog
-2.45   LRP5        NM_002335                                  receptor protein
                                Low-density lipoprotein receptor-related activity 5;LRP5;ortholog
-2.28   LRPAP1      NM_002337                                  lipid transporter activity
                                Alpha-2-macroglobulin receptor-associated protein;LRPAP1;ortholog
3.00    LRRC1       NM_018214   Leucine-rich repeat-containing protein 1;LRRC1;ortholog
-2.25   LRRC16      NM_017640   Leucine-rich repeat-containing protein 16A;LRRC16A;ortholog
3.70    LRRC20      NM_018205   Leucine-rich repeat-containing protein 20;LRRC20;ortholog
-2.34   LRRC45      NM_144999   Leucine-rich repeat-containing protein 45;LRRC45;ortholog
2.75    LRRN1       NM_020873                                  receptor activity
                                Leucine-rich repeat neuronal protein 1;LRRN1;ortholog
-2.43   LRRTM4      NM_024993                                    receptor activity
                                Leucine-rich repeat transmembrane neuronal protein 4;LRRTM4;ortholog
2.99    LRTM1       NM_020678                                    receptor activity
                                Leucine-rich repeat and transmembrane domain-containing protein 1;LRTM1;ort
3.18    LSM3        NM_014463                                    protein LSm3;LSM3;ortholog
                                U6 snRNA-associated Sm-like RNA splicing factor activity, transesterification me
-2.34   LY96        NM_015364   Lymphocyte antigen 96;LY96;ortholog
2.02    LYZL6       NM_020426                                    hydrolase
                                Lysozyme-like protein 6;LYZL6;ortholog activity
2.65    LZTFL1      NM_020347   Leucine zipper transcription factor-like protein 1;LZTFL1;ortholog
2.21    MACC1       NM_182762   SH3 domain-containing protein 7a5;7A5_HUMAN;ortholog
-2.24   MADD        NM_003682                                    protein binding;small GTPase
                                MAP kinase-activating death domain protein;MADD;ortholog regulator activity;gu
1.97    MAGEC2      NM_016249   Melanoma-associated antigen C2;MAGEC2;ortholog
-2.68   MAJN        NM_004740   Myosin-XVIIIa;MYO18A;ortholog    motor activity;structural constituent of cytoskeleto
2.13    MAN1        NM_014319   Inner nuclear membrane protein Man1;LEMD3;ortholog
-2.79   MANEA       NM_024641                                    hydrolase activity, hydrolyzing
                                Glycoprotein endo-alpha-1,2-mannosidase;MANEA;ortholog N-glycosyl compou
2.60    MAP17       NM_005764   PDZK1-interacting protein 1;PDZK1IP1;ortholog
2.32    MAP2        NM_002374                                     2;MAP2;ortholog
                                Microtubule-associated protein structural constituent of cytoskeleton;microtubule
8.38    MAPK13      NM_002754                                    protein kinase activity
                                Mitogen-activated protein kinase 13;MAPK13;ortholog
4.92    MAPK14      NM_001315                                    protein kinase activity
                                Mitogen-activated protein kinase 14;MAPK14;ortholog
3.18    MAPKAPK2    NM_004759                                    protein kinase activity
                                MAP kinase-activated protein kinase 2;MAPKAPK2;ortholog
-2.27   MAPRE1      NM_012325                                     RP/EB family member cytoskeleton;microtubule
                                Microtubule-associated protein structural constituent of1;MAPRE1;ortholog
4.25    MAPT        NM_005910                                     tau;MAPT;ortholog
                                Microtubule-associated protein structural constituent of cytoskeleton;microtubule
-2.24   MAST1       NM_014975                                    protein kinase activity
                                Microtubule-associated serine/threonine-protein kinase 1;MAST1;ortholog
4.76    MAST2       NM_015112                                    protein kinase activity
                                Microtubule-associated serine/threonine-protein kinase 2;MAST2;ortholog
-3.07   MBD4        NM_003925                                    methyltransferase activity;nuclease activity;nuclei
                                Methyl-CpG-binding domain protein 4;MBD4;ortholog
2.43    MCTS1       NM_014060                                    receptor activity
                                Malignant T cell amplified sequence 1;MCTS1;ortholog
-2.55   METRNL      XM_209073   Meteorin-like protein;METRNL;ortholog
2.11    METTL5      NM_014168   Methyltransferase-like protein 5;METTL5;ortholog
-2.51   MGC16121    NM_032762   NM_032762.2: This RefSeq was permanently suppressed because it is now tho
3.08    MGC21881    NM_203448   NM_203448.1 was permanently suppressed because currently there is support f
-2.22   MGC39821    NM_182576   This record was removed by RefSeq staff; the sequence does not appear to rep
-2.51   MGC50722    NM_203348   uncharacterized MGC50722 (MGC50722), mRNA
2.60    MGC9515     XM_375313   This record was removed as a result of standard genome annotation processing
9.60    MIA         NM_006533   Melanoma-derived growth regulatory protein;MIA;ortholog
-3.15   MIP         NM_012064                                    transmembrane
                                Lens fiber major intrinsic protein;MIP;ortholog transporter activity
19.18   MITF        NM_000248                                    transcription factor activity;transcription factor act
                                Microphthalmia-associated transcription factor;MITF;ortholog
-2.43   MLH3        NM_014381                                    DNA binding
                                DNA mismatch repair protein Mlh3;MLH3;ortholog
2.50    MLL         NM_005933                                    methyltransferase activity;DNA binding
                                Histone-lysine N-methyltransferase HRX;MLL;ortholog
5.77    MLL3        NM_021230                                    methyltransferase activity;DNA binding
                                Histone-lysine N-methyltransferase MLL3;MLL3;ortholog
3.23    MLSTD2      NM_032228                                    oxidoreductase activity
                                Fatty acyl-CoA reductase 1;FAR1;ortholog
-2.28   MMP12       NM_002426                                    metallopeptidase
                                Macrophage metalloelastase;MMP12;ortholog activity
2.30    MMP2        NM_004530                                    metallopeptidase activity
                                72 kDa type IV collagenase;MMP2;ortholog
2.45    MMP24       NM_006690                                    metallopeptidase activity
                                Processed matrix metalloproteinase-24;MMP24;ortholog
-2.55   MMP8        NM_002424                                    metallopeptidase activity
                                Neutrophil collagenase;MMP8;ortholog
2.23    MNS1        NM_018365                                    structural molecule activity
                                Meiosis-specific nuclear structural protein 1;MNS1;ortholog
2.30    MOAP1       NM_022151   Modulator of apoptosis 1;MOAP1;ortholog
3.00    MOGAT1,DC2 NM_058165                                     acyltransferase activity
                                2-acylglycerol O-acyltransferase 1;MOGAT1;ortholog
8.12    MPP1        NM_002436                                    protein;MPP1;ortholog
                                55 kDa erythrocyte membrane nucleotide kinase activity;protein kinase activity
7.79    MRPL20      NM_017971                                    structural constituent of ribosome;nucleic acid bin
                                39S ribosomal protein L20, mitochondrial;MRPL20;ortholog
-2.88   MRPL36,BRIP1NM_032479   39S ribosomal protein L36, mitochondrial;MRPL36;ortholog
2.78    MRPL40      NM_003776                                    structural constituent of ribosome;nucleic acid bin
                                39S ribosomal protein L40, mitochondrial;MRPL40;ortholog
3.26    MRPL46      NM_022163                                    structural constituent of ribosome;nucleic acid bin
                                39S ribosomal protein L46, mitochondrial;MRPL46;ortholog
2.47    MRPS12    NM_021107                                   structural constituent of ribosome;nucleic acid bin
                              28S ribosomal protein S12, mitochondrial;MRPS12;ortholog
-2.20   MRPS18A   NM_018135                                   structural constituent of ribosome;nucleic acid bin
                              28S ribosomal protein S18a, mitochondrial;MRPS18A;ortholog
3.24    MRPS23    NM_016070                                   structural constituent of ribosome;nucleic acid bin
                              28S ribosomal protein S23, mitochondrial;MRPS23;ortholog
3.43    MRPS33    NM_016071                                   structural constituent of ribosome;nucleic acid bin
                              28S ribosomal protein S33, mitochondrial;MRPS33;ortholog
5.28    MRPS7     NM_015971                                   structural constituent of ribosome;nucleic acid bin
                              28S ribosomal protein S7, mitochondrial;MRPS7;ortholog
3.94    MRRF      NM_138777                                   structural constituent of ribosome;nucleic acid bin
                              Ribosome-recycling factor, mitochondrial;MRRF;ortholog
2.02    MRVLDC3   NM_052858                                   transcription factor activity;protein binding;transcr
                              MARVEL domain-containing protein 3;MARVELD3;ortholog
3.24    MS4A1     NM_021950                                   receptor activity
                              B-lymphocyte antigen CD20;MS4A1;ortholog
-2.08   MSH4      NM_002440                                   damaged
                              MutS protein homolog 4;MSH4;ortholog DNA binding
3.83    MSN       NM_002444   Moesin;MSN;ortholog             structural constituent of cytoskeleton
2.95    MSRA      NM_012331                                   oxidoreductase activity
                              Peptide methionine sulfoxide reductase;MSRA;ortholog
-2.46   MSX2      NM_002449                                   transcription
                              Homeobox protein MSX-2;MSX2;ortholog factor activity;transcription factor act
2.88    MTHFD2    NM_006636                                   oxidoreductase activity;hydrolase activity;ligase a
                              Methenyltetrahydrofolate cyclohydrolase;MTHFD2;ortholog
-2.93   MTMR8     NM_017677   Myotubularin-related protein 8;MTMR8;ortholog
-2.81   MTRF1L    NM_019041                                   translation factor activity, nucleic acid
                              Peptide chain release factor 1-like, mitochondrial;MTRF1L;ortholog binding;tran
-2.38   MUC12     XM_379904   Mucin-12;MUC12;ortholog
4.06    MVK       NM_000431   Mevalonate kinase;MVK;ortholog  kinase activity
2.38    MYC       NM_002467                                   transcription
                              Myc proto-oncogene protein;MYC;ortholog factor activity;transcription factor act
-2.68   MYH7      NM_000257   Myosin-7;MYH7;ortholog          motor activity;structural constituent of cytoskeleto
5.31    MYH9      NM_002473   Myosin-9;MYH9;ortholog          motor activity;structural constituent of cytoskeleto
-3.40   MYL4      NM_002476                                   structural constituent of cytoskeleton;calcium ion
                              Myosin light chain 4;MYL4;ortholog
4.13    MYL9      NM_006097                                   structural constituent
                              Myosin regulatory light polypeptide 9;MYL9;ortholog of cytoskeleton;calcium ion
2.82    MYLK2     NM_033118                                   protein kinase activity
                              Myosin light chain kinase 2, skeletal/cardiac muscle;MYLK2;ortholog
-2.20   MYPN      NM_032578   Myopalladin;MYPN;ortholog structural constituent of cytoskeleton
2.57    NAALAD2   NM_005467                                   peptidase activity
                              N-acetylated-alpha-linked acidic dipeptidase 2;NAALAD2;ortholog
2.83    NALP10    NM_176821   NACHT, LRR and PYD domains-containing protein 10;NLRP10;ortholog
3.44    NALP14    NM_176822   NACHT, LRR and PYD domains-containing protein 14;NLRP14;ortholog
3.37    NAT14     NM_020378   N-acetyltransferase 14;NAT14;ortholog
-2.24   NBPF14    NM_015383   Neuroblastoma breakpoint family member 14;NBPF14;ortholog
3.23    NCAM2     NM_004540                                   phosphoprotein phosphatase activity;phosphopro
                              Neural cell adhesion molecule 2;NCAM2;ortholog
4.47    NCBP1     NM_002486                                   RNA splicing factor activity, transesterification me
                              Nuclear cap-binding protein subunit 1;NCBP1;ortholog
-2.03   NCF2      NM_000433                                   oxidoreductase activity
                              Neutrophil cytosol factor 2;NCF2;ortholog
-2.11   NCKAP1    NM_013436   Nck-associated protein 1;NCKAP1;ortholog
-2.26   NCOA5     NM_020967                                   receptor activity
                              Nuclear receptor coactivator 5;NCOA5;ortholog
-2.33   NCOA7     NM_181782   Nuclear receptor coactivator 7;NCOA7;ortholog
3.21    NDST2     NM_003635                                   transferase activity
                              Heparan sulfate N-sulfotransferase 2;NDST2;ortholog
3.95    NDUFAF1   NM_016013   Complex I intermediate-associated protein 30, mitochondrial;NDUFAF1;ortholog
2.44    NDUFB6    NM_002493   NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;NDUFB6;ortho
3.06    NECAP1    NM_015509   Adaptin ear-binding coat-associated protein 1;NECAP1;ortholog
                                                              ATPase activity, coupled to transmembrane move
-2.67   NEURL     NM_004210                                   ubiquitin-protein ligase activity
                              Neuralized-like protein 1;NEURL;ortholog
2.72    NEUROG2   NM_024019   Neurogenin-2;NEUROG2;ortholog   nuclease activity;transcription factor activity;trans
3.56    NF2       NM_000268   Merlin;NF2;ortholog             structural constituent of cytoskeleton
3.49    NFE2L1    NM_003204                                   transcription factor activity;transcription factor act
                              Nuclear factor erythroid 2-related factor 1;NFE2L1;ortholog
2.31    NFE2L3    NM_004289                                   transcription factor activity;transcription factor act
                              Nuclear factor erythroid 2-related factor 3;NFE2L3;ortholog
5.20    NFIC      NM_005597                                   transcription factor activity;transcription factor act
                              Nuclear factor 1 C-type;NFIC;ortholog
-2.16   NFKBIE    NM_004556   NF-kappa-B inhibitor epsilon;NFKBIE;ortholog
2.91    NID2      NM_007361   Nidogen-2;NID2;ortholog         receptor activity
-2.41   NIP30     NM_024946   NEFA-interacting nuclear protein NIP30;NIP30;ortholog
4.66    NIP7      NM_016101   60S ribosome subunit biogenesis protein NIP7 homolog;NIP7;ortholog
-2.28   NLN       NM_020726 Neurolysin, mitochondrial;NLN;ortholog
                                                              metallopeptidase activity
2.88    NME4                                                  nucleotide kinase activity
                  NM_005009 Nucleoside diphosphate kinase, mitochondrial;NME4;ortholog
3.56    NOG       NM_005450 Noggin;NOG;ortholog               receptor binding
5.96    NOL8      NM_017948 Nucleolar protein 8;NOL8;ortholog
3.74    NOLA1     NM_018983 H/ACA ribonucleoprotein complex subunit 1;GAR1;ortholog
                                                              structural constituent of ribosome;nucleic acid bin
3.53    NPDC1     NM_015392 Neural proliferation differentiation and control protein 1;NPDC1;ortholog
                                                              transcription factor activity;transcription factor act
-2.43   NPEPPS    NM_006310 Puromycin-sensitive aminopeptidase;NPEPPS;ortholog
                                                              metallopeptidase activity
-2.33   NR5A1     NM_004959 Steroidogenic factor 1;NR5A1;ortholog
                                                              ligand-dependent nuclear receptor activity;transcr
-2.38   NRCAM     NM_005010 Neuronal cell adhesion molecule;NRCAM;ortholog
                                                              phosphoprotein phosphatase activity;phosphopro
-2.25   NRIP2     NM_031474 Nuclear receptor-interacting protein 2;NRIP2;ortholog
                                                              aspartic-type endopeptidase activity;transcription
-2.80   NRN1      NM_016588 Neuritin;NRN1;ortholog
3.92    NSFL1C    NM_016143 NSFL1 cofactor p47;NSFL1C;ortholog
2.88    NSMAF     NM_003580 Protein FAN;NSMAF;ortholog protein binding
6.04    NSUN2     NM_017755 tRNA (cytosine-5-)-methyltransferase NSUN2;NSUN2;ortholog acid binding
                                                              methyltransferase activity;nucleic
-2.34   NTN2L     NM_006181 Netrin-2-like protein;NTN2L;ortholog
-2.62   NTN4      NM_021229 Netrin-4;NTN4;ortholog
-2.61   NUCB1     NM_006184 Nucleobindin-1;NUCB1;orthologucleic acid binding;calcium ion binding;calmodu
                                                              n
-2.18   NUDT10    NM_153183 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha;NUDT10;ortholog
-3.48   NXF       NM_178864 Neuronal PAS domain-containing protein 4;NPAS4;ortholog
-2.74   OASL      NM_003733 59 kDa 2'-5'-oligoadenylate synthetase-like protein;OASL;ortholog acid binding
                                                              nucleotidyltransferase activity;nucleic
-3.39   OAZ2      NM_002537 Ornithine decarboxylase antizyme 2;OAZ2;ortholog
                                                              protein binding;enzyme inhibitor activity
2.71    OCEL1     NM_024578 Occludin/ELL domain-containing protein 1;OCEL1;ortholog
                                                              transcription factor activity;transcription factor act
2.30    OCSP      NM_031945 Tetraspanin-10;TSPAN10;ortholog   receptor binding
3.24    ODAG      NM_021167 GATA zinc finger domain-containing protein factor activity;transcription factor act
                                                              transcription 1;GATAD1;ortholog
3.98    OGFOD1    NM_018233 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1;OGF
                                                              oxidoreductase activity;transferase activity
-2.81   OGFR      NM_007346 Opioid growth factor receptor;OGFR;ortholog
                                                              receptor activity
-2.56   OGFRL1    NM_024576 Opioid growth factor receptor-like protein 1;OGFRL1;ortholog
                                                              receptor activity
4.50    OLFML3    NM_020190 Olfactomedin-like protein 3;OLFML3;ortholog
                                                              receptor activity
-2.37   OPLAH     NM_017570 5-oxoprolinase;OPLAH;ortholog     hydrolase activity
2.51    OR10H5    XM_210787 Olfactory receptor 10H5;OR10H5;ortholog
2.63    OR1B1     XM_294534 Olfactory receptor 1B1;OR1B1;ortholog
-2.43   OR1J2     XM_373313 Olfactory receptor 1J2;OR1J2;ortholog
2.11    OR2K2     NM_205859 Olfactory receptor 2K2;OR2K2;ortholog
3.48    OR4F21    NM_001005504Olfactory receptor 4F21;OR4F21;ortholog
4.76    OR52A5    XM_372352 Olfactory receptor 52A5;OR52A5;ortholog
2.57    OR52H1    NM_001005289Olfactory receptor 52H1;OR52H1;ortholog
2.07    OR5K1     XM_372997 Olfactory receptor 5K1;OR5K1;ortholog
2.44    OR5L2     XM_372387 Olfactory receptor 5L2;OR5L2;ortholog
2.01    OR6B1     XM_374682 Olfactory receptor 6B1;OR6B1;ortholog
2.42    ORC3L     NM_012381 Origin recognition complex subunit 3;ORC3L;orthologbinding
                                                              DNA replication origin
-2.19   ORMDL3    NM_139280 ORM1-like protein 3;ORMDL3;ortholog
-2.70   OSBPL6    NM_032523 Oxysterol-binding protein-related protein 6;OSBPL6;ortholog
-2.54   OSGEPL1   NM_022353 Probable O-sialoglycoprotein endopeptidase 2;OSGEPL1;ortholog
                                                              metallopeptidase activity
2.15    OSTF1     NM_012382 Osteoclast-stimulating factor 1;OSTF1;ortholog
2.36    OTP       NM_032109 Homeobox protein orthopedia;OTP;orthologfactor activity;transcription factor act
                                                              transcription
-2.11   OTUD5     NM_017602 OTU domain-containing protein 5;OTUD5;ortholog
                                                              peptidase activity;nucleic acid binding
9.50    OVTN      NM_198185 Ovochymase-2;OVCH2;ortholog       serine-type peptidase activity
3.63    PAIP2     NM_016480 Polyadenylate-binding protein-interacting protein 2;PAIP2;ortholog
-2.18   PALB2     NM_024675 Partner and localizer of BRCA2;PALB2;ortholog
2.67    PALM       NM_002579 Paralemmin;PALM;ortholog
5.81    PAPD1      NM_018109 Poly(A) RNA polymerase, mitochondrial;PAPD1;ortholog
                                                             nucleotidyltransferase activity
-3.34   PAPLN      XM_370765 Papilin;PAPLN;ortholog          protein binding;serine-type endopeptidase inhibito
-1.96   PAPPA      NM_002581 Pappalysin-1;PAPPA;ortholog metallopeptidase activity
-1.99   PARF       NM_024718 Putative GTP-binding protein Parf;PARF;ortholog
                                                             GTPase activity;protein binding
2.40    PARP16     NM_017851 Poly [ADP-ribose] polymerase 16;PARP16;ortholog
5.49    PARPBP     NM_017915 UPF0419 protein C12orf48;C12orf48;ortholog
4.63    PASK                                                 transmembrane receptor protein kinase
                   NM_015148 PAS domain-containing serine/threonine-protein kinase;PASK;ortholog activity;tr
-2.14   PAX3       NM_000438 Paired box protein Pax-3;PAX3;ortholog
                                                             transcription factor activity;transcription factor act
-2.33   PCDH18     NM_019035 Protocadherin-18;PCDH18;orthologcalcium ion binding
-2.47   PCDH19     XM_033173, NM_020766                      calcium ion binding
                               Protocadherin-19;PCDH19;ortholog
-2.34   PCDHA9     NM_014005 Protocadherin alpha-9;PCDHA9;ortholog binding
                                                             calcium ion
-2.39   PCDHB13    NM_018933 Protocadherin beta-13;PCDHB13;ortholog binding
                                                             calcium ion
3.25    PCDHB4     NM_018938 Protocadherin beta-4;PCDHB4;orthologion binding
                                                             calcium
-2.52   PCDHB7     NM_018940 Protocadherin beta-7;PCDHB7;orthologion binding
                                                             calcium
-2.02   PCDHGA1    NM_018912 Protocadherin gamma-A1;PCDHGA1;ortholog
                                                             calcium ion binding
2.57    PCDHGA11   NM_018914 Protocadherin gamma-A11;PCDHGA11;ortholog
                                                             calcium ion binding
3.99    PCDHGA12   NM_003735 Protocadherin gamma-A12;PCDHGA12;ortholog
                                                             calcium ion binding
2.99    PCDHGA5    NM_018918 Protocadherin gamma-A5;PCDHGA5;ortholog
                                                             calcium ion binding
-2.21   PCDHGA9    NM_018921 Protocadherin gamma-A9;PCDHGA9;ortholog
                                                             calcium ion binding
3.23    PCDHGB3    NM_018924 Protocadherin gamma-B3;PCDHGB3;ortholog
                                                             calcium ion binding
3.71    PCDHGB7    NM_018927 Protocadherin gamma-B7;PCDHGB7;ortholog
                                                             calcium ion binding
-2.59   PCNXL2     NM_014801 Pecanex-like protein 2;PCNXL2;ortholog
-2.29   PCOLCE2    NM_013363 Procollagen C-endopeptidase enhancer 2;PCOLCE2;ortholog
                                                             metallopeptidase activity;serine-type peptidase ac
4.00    PCQAP      NM_015889 Mediator of RNA polymerase II transcription subunit 15;MED15;ortholog
6.59    PCTK2                                                protein kinase activity
                   NM_002595 Serine/threonine-protein kinase PCTAIRE-2;PCTK2;ortholog
3.76    PDCD1LG1   NM_014143 Programmed cell death 1 ligand 1;CD274;ortholog
-2.45   PDCD1LG2   NM_025239 Programmed cell death 1 ligand 2;PDCD1LG2;ortholog
5.99    PDGFA      NM_002607 Platelet-derived growth factor subunit A;PDGFA;ortholog
                                                             growth factor activity
2.57    PDZRN4     NM_013377 PDZ domain-containing RING finger protein 4;PDZRN4;ortholog
3.05    PEPD       NM_000285 Xaa-Pro dipeptidase;PEPD;ortholog
                                                             metallopeptidase activity;transcription factor activ
-2.69   PEX10      NM_002617 Peroxisome assembly protein 10;PEX10;ortholog
2.38    PGAM1      NM_002629 Phosphoglycerate mutase 1;PGAM1;ortholog transferase activity
                                                             intramolecular
-2.19   PGAP1      NM_024989 GPI inositol-deacylase;PGAP1;ortholog
                                                             transmembrane transporter activity
3.56    PGLS       NM_012088 6-phosphogluconolactonase;PGLS;ortholog
                                                             hydrolase activity
-2.77   PGLYRP4    NM_020393 Peptidoglycan recognition protein I-beta;PGLYRP4;ortholog
                                                             receptor activity;receptor binding
3.81    PGPEP1     NM_017712 Pyroglutamyl-peptidase 1;PGPEP1;ortholog peptidase activity
                                                             cysteine-type
2.43    PHAX       NM_032177 Phosphorylated adapter RNA export binding
                                                             RNA protein;PHAX;ortholog
4.73    PHF10      NM_018288 PHD finger protein 10;PHF10;ortholog
                                                             acetyltransferase activity;transcription factor activ
5.58    PHF21B     NM_138415 PHD finger protein 21B;PHF21B;ortholog
                                                             ubiquitin-protein ligase activity
-2.67   PHGDH      NM_006623 D-3-phosphoglycerate dehydrogenase;PHGDH;ortholog
                                                             oxidoreductase activity
-2.16   PHYH       NM_006214 Phytanoyl-CoA dioxygenase, peroxisomal;PHYH;ortholog
                                                             oxidoreductase activity
-2.70   PHYHIPL    NM_032439 Phytanoyl-CoA hydroxylase-interacting protein-like;PHYHIPL;ortholog
4.36    PI15       NM_015886 Peptidase inhibitor 15;PI15;ortholog
2.95    PICALM     NM_007166 Phosphatidylinositol-binding clathrin assembly protein;PICALM;ortholog
4.54    PIH1D1     NM_017916 PIH1 domain-containing protein 1;PIH1D1;ortholog
2.31    PILRB      NM_013440 Paired immunoglobulin-like type 2 receptor beta;PILRB;ortholog
-2.06   PIPPIN     NM_014460 Cold shock domain-containing RNA binding
                                                             protein C2;CSDC2;ortholog
2.66    PIR51      NM_006479 RAD51-associated protein 1;RAD51AP1;ortholog
-2.52   PKD2L1      NM_016112                                   ion channel activity
                                Polycystic kidney disease 2-like 1 protein;PKD2L1;ortholog
-2.16   PLA2G2D     NM_012400                                   phospholipase activity
                                Group IID secretory phospholipase A2;PLA2G2D;ortholog
-2.52   PLA2G6      NM_003560                                   phospholipase activity
                                85 kDa calcium-independent phospholipase A2;PLA2G6;ortholog
-2.27   PLA2R1      NM_007366                                   receptor activity
                                Soluble secretory phospholipase A2 receptor;PLA2R1;ortholog
-2.15   PLAC3       NM_020318   Pappalysin-2;PAPPA2;orthologmetallopeptidase activity
3.26    PLDN        NM_012388   Pallidin;PLDN;ortholog
-2.39   PLEKHF2     NM_024613                                   transcription factor activity;transcription factor act
                                Pleckstrin homology domain-containing family F member 2;PLEKHF2;ortholog
7.10    PLEKHG3     XM_085127   Pleckstrin homology domain-containing family G member 3;PLEKHG3;ortholog
3.20    PLEKHG4     XM_290684   Puratrophin-1;PLEKHG4;ortholog  protein binding;small GTPase regulator activity;gu
2.66    PLEKHJ1     NM_018049                                   protein binding;small GTPase regulator activity;gu
                                Pleckstrin homology domain-containing family J member 1;PLEKHJ1;ortholog
-2.70   PLSCR2      NM_020359   Phospholipid scramblase 2;PLSCR2;ortholog
2.40    PLTP        NM_006227   Phospholipid transfer protein;PLTP;ortholog
2.40    PMAIP1      NM_021127   Phorbol-12-myristate-13-acetate-induced protein 1;PMAIP1;ortholog
-3.13   PMS2        NM_000535                                    PMS2;PMS2;ortholog
                                Mismatch repair endonuclease DNA binding
2.38    PNPLA2      NM_020376   Patatin-like phospholipase domain-containing protein 2;PNPLA2;ortholog
                                                                acyltransferase activity;phospholipase activity
3.74    PNPO        NM_018129                                   oxidoreductase activity
                                Pyridoxine-5'-phosphate oxidase;PNPO;ortholog
2.87    POLA        NM_016937                                   DNA-directed DNA polymerase activity;exodeoxy
                                DNA polymerase alpha catalytic subunit;POLA1;ortholog
4.96    POLE3       NM_017443                                   DNA-directed DNA polymerase activity;transcripti
                                DNA polymerase epsilon subunit 3;POLE3;ortholog
3.89    POLE4       NM_019896                                   DNA-directed DNA polymerase activity;transcripti
                                DNA polymerase epsilon subunit 4;POLE4;ortholog
2.45    POLR1B      NM_019014                                    I subunit RPA2;POLR1B;ortholog
                                DNA-directed RNA polymeraseDNA-directed RNA polymerase activity;nucleotidy
3.50    POLR2J4     XM_379817   polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene (POLR2J4), no
-2.81   POM121L1    NM_014348   POM121-like protein 1;POM121L1;ortholog
-2.52   POM121L12   NM_182595   POM121-like protein DKFZp564N2472;YG052_HUMAN;ortholog
2.73    POSTN       NM_006475   Periostin;POSTN;ortholog        receptor binding
-1.97   POU5F1      NM_002701                                   transcription factor activity;transcription factor act
                                POU domain, class 5, transcription factor 1;POU5F1;ortholog
-2.13   PPEF1       NM_006240                                   phosphoprotein phosphatase activity;phosphopro
                                Serine/threonine-protein phosphatase with EF-hands 1;PPEF1;ortholog
3.36    PPFIA2      NM_003625   Liprin-alpha-2;PPFIA2;ortholog
-2.68   PPP1CA      NM_002708                                   phosphoprotein phosphatase activity;phosphopro
                                Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;PPP1CA;orth
2.58    PPP1R11     NM_021959   Protein phosphatase 1 regulatory subunit 11;PPP1R11;ortholog
3.43    PPP1R15A    NM_014330   Protein phosphatase 1 regulatory subunit 15A;PPP1R15A;ortholog
3.15    PPP1R1A     NM_006741                                   receptor binding;phosphatase inhibitor activity;ph
                                Protein phosphatase 1 regulatory subunit 1A;PPP1R1A;ortholog
4.33    PPP1R7      NM_002712                                   structural 7;PPP1R7;ortholog
                                Protein phosphatase 1 regulatory subunitconstituent of cytoskeleton;protein bind
3.72    PPP2R5A     NM_006243                                   phosphoprotein phosphatase activity;phosphopro
                                Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isofor
5.74    PPP3R2      NM_147180                                   phosphoprotein
                                Calcineurin subunit B type 2;PPP3R2;ortholog phosphatase activity;phosphopro
-2.79   PPT2        NM_005155                                   hydrolase activity, acting on ester bonds
                                Lysosomal thioesterase PPT2;PPT2;ortholog
2.65    PQLC2       NM_017765   PQ-loop repeat-containing protein 2;PQLC2;ortholog
-2.67   PRCC        NM_005973   Proline-rich protein PRCC;PRCC;ortholog
2.86    PRDM11      NM_020229   PR domain-containing protein 11;PRDM11;ortholog
3.63    PRDM2       NM_012231                                   transcription factor
                                PR domain zinc finger protein 2;PRDM2;ortholog activity;transcription factor act
2.32    PREB        NM_013388                                   DNA protein;PREB;ortholog
                                Prolactin regulatory element-binding binding
-2.51   PRG-3       NM_017753   Lipid phosphate phosphatase-related protein type 1;LPPR1;ortholog
-2.70   PRKAB1      NM_006253                                   protein binding;kinase regulator activity
                                5'-AMP-activated protein kinase subunit beta-1;PRKAB1;ortholog
11.69   PRKCI       NM_002740                                   protein kinase activity;calcium ion binding;calmod
                                Protein kinase C iota type;PRKCI;ortholog
9.19    PRKG1       NM_006258                                   protein kinase activity
                                cGMP-dependent protein kinase 1, beta isozyme;PRKG1;ortholog
-2.67   PRND        NM_012409   Prion-like protein doppel;PRND;ortholog
-3.09   PRR14       NM_024031   Proline-rich protein 14;PRR14;ortholog
-2.01   PRRX2       NM_016307                                   transcription factor activity;transcription factor act
                                Paired mesoderm homeobox protein 2;PRRX2;ortholog
3.95    PRX         NM_181882   Periaxin;PRX;ortholog
3.34    PSAP        NM_002778   Saposin-D;PSAP;ortholog         protein binding;enzyme regulator activity
-2.15   PTP4A1     NM_003463                                   phosphoprotein phosphatase
                               Protein tyrosine phosphatase type IVA 1;PTP4A1;ortholog activity;phosphopro
3.26    PTPN23     NM_015466                                   phosphoprotein phosphatase activity;phosphopro
                               Tyrosine-protein phosphatase non-receptor type 23;PTPN23;ortholog
-2.59   PTPRA      NM_002836                                    phosphatase alpha;PTPRA;ortholog
                               Receptor-type tyrosine-protein phosphoprotein phosphatase activity;phosphopro
-2.63   PTPRC      NM_002838                                   phosphoprotein
                               Leukocyte common antigen;PTPRC;ortholog phosphatase activity;phosphopro
-3.14   PTPRN2     NM_002847                                    phosphatase N2;PTPRN2;ortholog
                               Receptor-type tyrosine-protein phosphoprotein phosphatase activity;phosphopro
-2.29   PTPRU      NM_005704                                    phosphatase U;PTPRU;ortholog
                               Receptor-type tyrosine-protein phosphoprotein phosphatase activity;phosphopro
2.61    PTTG1      NM_004219   Securin;PTTG1;ortholog          transcription factor activity;transcription factor act
2.16    PURA       NM_005859                                   single-stranded DNA binding;transcription factor a
                               Transcriptional activator protein Pur-alpha;PURA;ortholog
-2.30   PUS1       NM_025215                                   lyase activity
                               tRNA pseudouridine synthase A;PUS1;ortholog
2.97    PVRL3      NM_015480                                   receptor activity
                               Poliovirus receptor-related protein 3;PVRL3;ortholog
3.83               XM_056455
        PXDN,PRG2,MG50                                         oxidoreductase activity;peroxidase activity
                               Peroxidasin homolog;PXDN;ortholog
3.09    QPCTL      NM_017659                                   transferase activity
                               Glutaminyl-peptide cyclotransferase-like protein;QPCTL;ortholog
4.95    QRSL1      NM_018292                                   transferase activity;hydrolase activity;ligase
                               Glutamyl-tRNA(Gln) amidotransferase subunit A homolog;QRSL1;ortholog activi
-2.50   RAB21      NM_014999                                   GTPase activity;protein binding
                               Ras-related protein Rab-21;RAB21;ortholog
2.84    RAB3IL1    NM_013401                                   protein binding;small GTPase regulator activity;gu
                               Guanine nucleotide exchange factor for Rab3A;RAB3IL1;ortholog
-3.29   RAB5A      NM_004162                                   GTPase activity;protein binding
                               Ras-related protein Rab-5A;RAB5A;ortholog
2.54    RAB6B      NM_016577                                   GTPase activity;protein binding
                               Ras-related protein Rab-6B;RAB6B;ortholog
-3.48   RAB7A      NM_004637                                   GTPase activity;protein binding
                               Ras-related protein Rab-7a;RAB7A;ortholog
3.05    RAB7B      NM_177403                                   GTPase activity;protein binding
                               Ras-related protein Rab-7b;RAB7B;ortholog
-2.28   RABIF      NM_002871                                   protein binding;small GTPase
                               Guanine nucleotide exchange factor MSS4;RABIF;ortholog regulator activity;gu
-3.08   RAC4       XM_210062   This record was removed as a result of standard genome annotation processing
-2.03   RAD54L2    NM_015106                                   DNA
                               Helicase ARIP4;RAD54L2;ortholog helicase activity;nucleic acid binding
1.99    RAD9A      NM_004584                                   protein binding;kinase activator
                               Cell cycle checkpoint control protein RAD9A;RAD9A;ortholog activity;kinase reg
4.83    RAG1       NM_000448                                     protein 1;RAG1;ortholog
                               V(D)J recombination-activatingendodeoxyribonuclease activity;nucleic acid bindi
2.24    RAI14      NM_015577   Ankycorbin;RAI14;ortholog
2.97    RAMP       NM_015430                                   serine-type peptidase activity
                               Inactive serine protease RAMP;RAMP;ortholog
2.21    RAMP3      NM_005856                                   receptor activity
                               Receptor activity-modifying protein 3;RAMP3;ortholog
-3.31   RANBP10    NM_020850                                   transmembrane transporter activity
                               Ran-binding protein 10;RANBP10;ortholog
-2.13   RAP1GAP    NM_002885                                   protein binding;small GTPase regulator activity
                               Rap1 GTPase-activating protein 1;RAP1GAP;ortholog
-2.30   RAPGEF1    NM_005312                                   protein binding;small GTPase regulator activity;gu
                               Rap guanine nucleotide exchange factor 1;RAPGEF1;ortholog
2.74    RAPGEFL1   NM_016339                                   protein binding;small GTPase regulator
                               Rap guanine nucleotide exchange factor-like 1;RAPGEFL1;ortholog activity;gu
3.80    RASGRP1    NM_005739                                   protein binding;small
                               RAS guanyl-releasing protein 1;RASGRP1;ortholog GTPase regulator activity;gu
3.59    RBAK       NM_021163                                   transcription factor activity;transcription factor act
                               RB-associated KRAB zinc finger protein;RBAK;ortholog
-2.73   RBBP6      NM_006910                                     6;RBBP6;ortholog
                               Retinoblastoma-binding proteinnuclease activity;nucleic acid binding
3.13    RBM25      XM_027330                                   RNA binding
                               Probable RNA-binding protein 25;RBM25;ortholog
4.23    RBM28      NM_018077                                   RNA binding
                               RNA-binding protein 28;RBM28;ortholog
2.57    RBMX2      NM_016024                                   RNA binding
                               RNA-binding motif protein, X-linked 2;RBMX2;ortholog
-2.34   RCAN1      NM_004414   Calcipressin-1;RCAN1;ortholog   receptor binding
3.28    RCC2       NM_018715   Protein RCC2;RCC2;ortholog
-2.00   RCN3       NM_020650   Reticulocalbin-3;RCN3;ortholog  calcium ion binding;calmodulin binding
3.29    RCOR1      NM_015156                                   DNA binding
                               REST corepressor 1;RCOR1;ortholog
3.35    RCOR3      NM_018254                                   DNA binding
                               REST corepressor 3;RCOR3;ortholog
3.05    RDH11      NM_016026                                   oxidoreductase activity
                               Retinol dehydrogenase 11;RDH11;ortholog
3.04    REP15      XM_370686   Rab15 effector protein;REP15;ortholog
2.21    RESP18     XM_371593   Triskadecapeptide;RESP18;ortholog
2.94    RETN       NM_020415   Resistin;RETN;ortholog
4.12    RFC4       NM_002916                                   DNA-directed
                               Replication factor C subunit 4;RFC4;ortholog DNA polymerase activity;nucleotidy
3.17    RFPL4A     XM_292796   Ret finger protein-like 4A;RFPL4A;ortholog
4.77    RFX5       NM_000449                                   nuclease activity;transcription factor activity;trans
                               DNA-binding protein RFX5;RFX5;ortholog
2.18    RGAG4     XM_291322 Retrotransposon gag domain-containing protein 4;Rgag4;ortholog
-3.16   RGL4      NM_153615 Ral-GDS-related protein;RGL4;ortholog
                                                             protein binding;small GTPase regulator activity;gu
4.28    RGMA      NM_020211 Repulsive guidance molecule A;RGMA;ortholog
-1.97   RGNEF     XM_371755, NM_001080479nucleotide exchange factor;RGNEF;ortholog
                              Rho-guanine
3.59    RGS8      NM_033345 Regulator of G-protein signaling 8;RGS8;ortholog GTPase regulator activity
                                                             protein binding;small
2.59    RHBG      NM_020407 Ammonium transporter Rh type B;RHBG;ortholog
                                                             cation transmembrane transporter activity
2.34    RHCE      NM_020485 Blood group Rh(CE) polypeptide;RHCE;ortholog
                                                             cation transmembrane transporter activity
-2.50   RHOV      NM_133639 Rho-related GTP-binding protein RhoV;RHOV;orthologbinding
                                                             GTPase activity;protein
3.20    RHPN2     NM_033103 Rhophilin-2;RHPN2;ortholog
3.29    RIN1      NM_004292 Ras and Rab interactor 1;RIN1;ortholog
                                                             protein binding;small GTPase regulator activity;gu
2.29    RING1     NM_002931 E3 ubiquitin-protein ligase RING1;RING1;ortholog activity;transcription factor act
                                                             transcription factor
-2.55   RIPK1                                                protein kinase activity
                  NM_003804 Receptor-interacting serine/threonine-protein kinase 1;RIPK1;ortholog
-2.54   RIPX      NM_014961 Protein RUFY3;RUFY3;orthologranscription factor activity;transcription factor act
                                                             t
3.15    RKHD2     NM_016626 RNA-binding protein MEX3C;MEX3C;ortholog ligase activity;RNA binding
                                                             ubiquitin-protein
3.84    RNF126    NM_017876 RING finger protein 126;RNF126;ortholog
2.75    RNF138    NM_016271 E3 ubiquitin-protein ligase RNF138;RNF138;ortholog
                                                             transcription factor activity;transcription factor act
7.82    RNF14     NM_004290 E3 ubiquitin-protein ligase RNF14;RNF14;ortholog
                                                             ubiquitin-protein ligase activity;transcription factor
-2.23   RNF151    XM_370927 RING finger protein 151;RNF151;ortholog
4.02    RNF2                                                 transcription factor
                  NM_007212 E3 ubiquitin-protein ligase RING2;RNF2;ortholog activity;transcription factor act
-3.29   RNF25     NM_022453 E3 ubiquitin-protein ligase RNF25;RNF25;orthologactivity;transcription factor act
                                                             transcription factor
-2.17   RNF26     NM_032015 RING finger protein 26;RNF26;ortholog
                                                             ubiquitin-protein ligase activity
-2.02   RNF30     NM_032546 Tripartite motif-containing protein 54;TRIM54;ortholog activity
                                                             ubiquitin-protein ligase
-2.98   RNF32     NM_030936 RING finger protein 32;RNF32;ortholog
5.24    RNF38     NM_022781 RING finger protein 38;RNF38;ortholog
2.32    RNF44     NM_014901 RING finger protein 44;RNF44;ortholog
11.91   RP2       NM_006915 Protein XRP2;RP2;ortholog        nucleotide kinase activity
2.06    RPS6KB2                                              protein kinase activity
                  NM_003952 Ribosomal protein S6 kinase beta-2;RPS6KB2;ortholog
2.29    RPS6KB2                                              protein kinase activity
                  NM_003952 Ribosomal protein S6 kinase beta-2;RPS6KB2;ortholog
3.12    RS1       NM_000330 Retinoschisin;RS1;ortholog       metallopeptidase activity;serine-type peptidase ac
-2.30   RTN4      NM_007008 Reticulon-4;RTN4;ortholog
2.36    RTN4RL1   NM_178568 Reticulon-4 receptor-like 1;RTN4RL1;ortholog
                                                             receptor activity
2.47    RUTBC3    NM_015705 Small G protein signaling modulator 3;SGSM3;ortholog
                                                             protein binding;small GTPase regulator activity
5.20    RUVBL2    NM_006666 RuvB-like 2;RUVBL2;ortholog DNA helicase activity;transcription factor activity;t
-2.50   RYR2      NM_001035 Ryanodine receptor 2;RYR2;ortholog activity;ligand-gated ion channel activity
                                                             receptor
2.91    SAPS3     NM_018312 Serine/threonine-protein phosphatase 6 regulatory subunit 3;SAPS3;ortholog
                                                             protein binding;phosphatase regulator activity
3.16    SARA1     NM_020150 GTP-binding protein SAR1a;SAR1A;ortholog
                                                             GTPase activity;protein binding
2.30    SARG      NM_023938 Specifically androgen-regulated gene protein;SARG;ortholog
4.36    SASH1     NM_015278 SAM and SH3 domain-containing protein 1;SASH1;ortholog
-2.63   SCAMP4    NM_079834 Secretory carrier-associated membrane protein 4;SCAMP4;ortholog
                                                             transferase activity
3.09    SCAP2     NM_003930 Src kinase-associated phosphoprotein 2;SKAP2;ortholog
3.46    SCHIP1    NM_014575 Schwannomin-interacting protein 1;SCHIP1;ortholog
-2.12   SCNN1B    NM_000336 Amiloride-sensitive sodium channel subunitactivity
                                                             ion channel beta;SCNN1B;ortholog
2.69    SCP2      NM_002979 Non-specific lipid-transfer protein;SCP2;ortholog
                                                             oxidoreductase activity
-2.97   SCRT2     NM_033129 Transcriptional repressor scratch 2;SCRT2;ortholog
                                                             transcription factor activity;transcription factor act
2.51    SCUBE1    NM_173050 Signal peptide, CUB and EGF-like domain-containing protein 1;SCUBE1;ortholo
-2.09   SDPR      NM_004657 Serum deprivation-response protein;SDPR;ortholog
                                                             transcription factor activity;transcription factor act
2.60    SEC22B    NM_004892 Vesicle-trafficking protein SEC22b;SEC22B;ortholog
                                                             SNAP receptor activity
3.15    SEMA3A    NM_006080 Semaphorin-3A;SEMA3A;ortholog    receptor binding
-2.38   SEMA4D    NM_006378 Semaphorin-4D;SEMA4D;ortholog    receptor binding
3.65    SEMA5B      NM_018987   Semaphorin-5B;SEMA5B;ortholog      receptor binding
6.58    SERF1B      NM_022978   Small EDRK-rich factor 1;SERF1B;ortholog
2.18    SERHL2      NM_014509                                      serine-type peptidase activity
                                Serine hydrolase-like protein 2;SERHL2;ortholog
-2.17   SERPINB12   NM_080474   Serpin B12;SERPINB12;ortholog      protein binding;serine-type endopeptidase inhibito
2.55    SERPINC1    NM_000488                                      protein
                                Antithrombin-III;SERPINC1;ortholog binding;serine-type endopeptidase inhibito
4.16    SERPIND1    NM_000185                                      protein binding;serine-type endopeptidase inhibito
                                Heparin cofactor 2;SERPIND1;ortholog
-2.24   SERPINE2    NM_006216                                      protein
                                Glia-derived nexin;SERPINE2;orthologbinding;serine-type endopeptidase inhibito
-2.74   SERPINH1    NM_001235   Serpin H1;SERPINH1;orthologprotein binding;serine-type endopeptidase inhibito
-3.46   SERPINI1    NM_005025                                      p
                                Neuroserpin;SERPINI1;ortholog rotein binding;serine-type endopeptidase inhibito
-3.08   SERTAD2     XM_376059                                      transcription factor activity;transcription factor act
                                SERTA domain-containing protein 2;SERTAD2;ortholog
3.15    SERTAD4     NM_019605   SERTA domain-containing protein 4;SERTAD4;ortholog
2.92    SFRP1       NM_003012                                      receptor binding
                                Secreted frizzled-related protein 1;SFRP1;ortholog
2.16    SFRS11      NM_004768   Splicing factor, arginine/serine-rich 11;SFRS11;ortholog
2.75    SFRS2       NM_003016                                      RNA splicing factor activity, transesterification me
                                Splicing factor, arginine/serine-rich 2;SFRS2;ortholog
3.28    SFRS4       NM_005626                                      RNA splicing factor activity, transesterification me
                                Splicing factor, arginine/serine-rich 4;SFRS4;ortholog
3.22    SGK494      NM_144610                                      protein kinase activity
                                Uncharacterized serine/threonine-protein kinase SgK494;SGK494;ortholog
-2.72   SH2D1A      NM_002351   SH2 domain-containing protein 1A;SH2D1A;ortholog
10.41   SH3KBP1     NM_031892                                      receptor binding
                                SH3 domain-containing kinase-binding protein 1;SH3KBP1;ortholog
3.69    SHAX3       NM_152284   Charged multivesicular body protein 4c;CHMP4C;ortholog
-2.53   SHB         NM_003028   SH2 domain-containing adapter protein B;SHB;ortholog
-2.99   SHBG        NM_001040   Sex hormone-binding globulin;SHBG;ortholog
-3.59   SHF         XM_032304   SH2 domain-containing adapter protein F;SHF;ortholog
2.95    SHFM3       NM_022039   F-box/WD repeat-containing protein 4;FBXW4;ortholog
-2.20   SHREW1      NM_018836   Adherens junction-associated protein 1;AJAP1;ortholog
2.23    SIAH1       NM_003031                                      ubiquitin-protein ligase activity
                                E3 ubiquitin-protein ligase SIAH1;SIAH1;ortholog
-2.07   SIGLEC10    NM_033130                                       10;SIGLEC10;ortholog
                                Sialic acid-binding Ig-like lectin receptor activity;receptor binding
3.34    SIGLEC11    NM_052884                                       11;SIGLEC11;ortholog
                                Sialic acid-binding Ig-like lectin receptor activity;receptor binding
4.17    SIN3A       NM_015477                                      deacetylase activity;transcription factor activity;ch
                                Paired amphipathic helix protein Sin3a;SIN3A;ortholog
4.27    SIPA1       NM_006747                                      protein binding;small GTPase regulator activity
                                Signal-induced proliferation-associated protein 1;SIPA1;ortholog
-2.25   SIRT2       NM_012237                                      deacetylase activity;nucleic acid binding;chromati
                                NAD-dependent deacetylase sirtuin-2;SIRT2;ortholog
-2.15   SLC13A3     NM_022829                                      cation transmembrane
                                Solute carrier family 13 member 3;SLC13A3;ortholog transporter activity
-2.35   SLC25A21    NM_030631   Mitochondrial 2-oxodicarboxylate carrier;SLC25A21;ortholog
-2.94   SLC26A8     NM_052961                                      transmembrane
                                Testis anion transporter 1;SLC26A8;ortholog transporter activity
-2.47   SLC26A9     NM_052934                                      transmembrane transporter activity
                                Solute carrier family 26 member 9;SLC26A9;ortholog
2.51    SLC2A3      NM_006931                                      carbohydrate transmembrane 3;SLC2A3;ortholo
                                Solute carrier family 2, facilitated glucose transporter membertransporter activity
2.50    SLC2A8      NM_014580                                      carbohydrate transmembrane 8;SLC2A8;ortholo
                                Solute carrier family 2, facilitated glucose transporter membertransporter activity
3.76    SLC35C1     NM_018389                                      transmembrane
                                GDP-fucose transporter 1;SLC35C1;ortholog transporter activity
3.47    SLC35C2     NM_015945                                      transmembrane transporter activity
                                Solute carrier family 35 member C2;SLC35C2;ortholog
-2.27   SLC36A1     NM_078483   Proton-coupled amino acid transporter 1;SLC36A1;ortholog
2.05    SLC37A1     NM_018964                                      transmembrane transporter activity
                                Glycerol-3-phosphate transporter;SLC37A1;ortholog
3.09    SLC38A8     XM_085347   Putative sodium-coupled neutral amino acid transporter 8;SLC38A8;ortholog
2.88    SLC39A14    NM_015359                                      transmembrane transporter activity
                                Zinc transporter ZIP14;SLC39A14;ortholog
-2.28   SLC39A2     NM_014579                                      transmembrane transporter activity
                                Zinc transporter ZIP2;SLC39A2;ortholog
-2.83   SLC39A4     NM_017767                                      transmembrane transporter activity
                                Zinc transporter ZIP4;SLC39A4;ortholog
6.03    SLC43A1     NM_003627   Large neutral amino acids transporter small subunit 3;SLC43A1;ortholog
2.99    SLC4A1      NM_000342                                      transmembrane transporter activity
                                Band 3 anion transport protein;SLC4A1;ortholog
-3.25   SLC4A4      NM_003759                                      cation transmembrane transporter activity
                                Electrogenic sodium bicarbonate cotransporter 1;SLC4A4;ortholog
3.01    SLC5A1      NM_000343                                      carbohydrate transmembrane transporter activity
                                Sodium/glucose cotransporter 1;SLC5A1;ortholog
3.10    SLC6A20     NM_020208                                      amino acid transmembrane transporter activity;ca
                                Sodium- and chloride-dependent transporter XTRP3;SLC6A20;ortholog
4.80    SLC7A11    NM_014331                                   amino acid transmembrane transporter activity;tra
                               Cystine/glutamate transporter;SLC7A11;ortholog
-1.99   SLC7A7     NM_003982                                   amino acid transmembrane transporter activity;tra
                               Y+L amino acid transporter 1;SLC7A7;ortholog
3.97    SLC9A3     NM_004174                                   cation transmembrane transporter activity
                               Sodium/hydrogen exchanger 3;SLC9A3;ortholog
2.17    SLC9A7     NM_032591                                   cation transmembrane transporter activity
                               Sodium/hydrogen exchanger 7;SLC9A7;ortholog
-2.08   SLITRK2    NM_032539                                   receptor activity
                               SLIT and NTRK-like protein 2;SLITRK2;ortholog
-2.28   SMAP-1     NM_018671   Protein unc-45 homolog A;UNC45A;ortholog
-2.10   SMARCA4    NM_003072                                   DNA helicase activity;nucleic acid binding
                               Probable global transcription activator SNF2L4;SMARCA4;ortholog
2.35    SMARCAL1   NM_014140                                   DNA helicase activity;nucleic acid chromatin subf
                               SWI/SNF-related matrix-associated actin-dependent regulator of binding
2.67    SMARCD1    NM_003076                                   nucleic acid binding;chromatin of chromatin subf
                               SWI/SNF-related matrix-associated actin-dependent regulatorbinding
-2.26   SMEK1      NM_032560   Serine/threonine-protein phosphatase 4 regulatory subunit 3A;SMEK1;ortholog
3.67    SMOX       NM_019025   Spermine oxidase;SMOX;ortholog  oxidoreductase activity;nucleic acid binding
3.04    SMP1       NM_014313   Transmembrane protein 50A;TMEM50A;ortholog
1.99    SMPD4      NM_017751   Sphingomyelin phosphodiesterase 4;SMPD4;ortholog
-2.39   SNAI2      NM_003068                                   transcription
                               Zinc finger protein SNAI2;SNAI2;ortholog factor activity;transcription factor act
3.75    SNX12      NM_013346   Sorting nexin-12;SNX12;ortholog
-3.68   SNX9       NM_016224   Sorting nexin-9;SNX9;ortholog
2.86    SOST       NM_025237   Sclerostin;SOST;ortholog        receptor binding
-2.27   SP4        NM_003112                                   transcription factor activity;transcription factor act
                               Transcription factor Sp4;SP4;ortholog
-2.51   SPATA7     NM_018418   Spermatogenesis-associated protein 7;SPATA7;ortholog
2.11    SPC18      NM_014300                                   serine-type SEC11A;SEC11A;ortholog
                               Signal peptidase complex catalytic subunit peptidase activity
2.96    SPC25      NM_020675   Kinetochore protein Spc25;SPC25;ortholog
-3.43   SPDYC      XM_370631   Speedy protein C;SPDYC;ortholog
2.95    SPG4       NM_014946   Spastin;SPAST;ortholog          hydrolase activity;structural constituent of cytoske
2.65    SPIN       NM_006717   Spindlin-1;SPIN1;ortholog
-2.06   SPINK5     NM_006846                                   protein binding
                               Hemofiltrate peptide HF7665;SPINK5;ortholog
-2.32   SPINT2     NM_021102                                   protein binding;serine-type endopeptidase inhibito
                               Kunitz-type protease inhibitor 2;SPINT2;ortholog
-2.06   SPOCD1     NM_144569   SPOC domain-containing protein 1;SPOCD1;ortholog
2.53    SPOCK3     NM_016950   Testican-3;SPOCK3;ortholog calcium ion binding;protein binding;cysteine-type
-2.13   SPRY4      NM_030964                                   transcription
                               Protein sprouty homolog 4;SPRY4;ortholog factor activity;receptor binding;transc
-2.50   SRCRB4D    NM_080744                                   receptor activity
                               Scavenger receptor cysteine-rich domain-containing group B protein;SRCRB4D;
3.03    SRPUL      NM_014467   Sushi repeat-containing protein SRPX2;SRPX2;ortholog
-2.03   SSB3       NM_080861   SPRY domain-containing SOCS box protein 3;SPSB3;ortholog
-2.20   SSR1       NM_003144                                   subunit ion binding
                               Translocon-associated protein calcium alpha;SSR1;ortholog
2.26    SSX1       NM_005635   Protein SSX1;SSX1;ortholog transcription factor activity;transcription factor act
2.83    STAP2      NM_017720                                   transmembrane receptor protein kinase activity;tr
                               Signal-transducing adaptor protein 2;STAP2;ortholog
-2.21   STAT1      NM_007315                                    of transcription 1-alpha/beta;STAT1;ortholog
                               Signal transducer and activatortranscription factor activity;transcription factor act
4.29    STEAP      NM_012449   Metalloreductase STEAP1;STEAP1;ortholog
-2.54   STEAP1B    NM_207342   STEAP family protein MGC87042;STEAL_HUMAN;ortholog
-1.96   STK32B     NM_018401                                   protein kinase activity
                               Serine/threonine-protein kinase 32B;STK32B;ortholog
2.82    STK4       NM_006282                                   protein kinase activity
                               Serine/threonine-protein kinase 4;STK4;ortholog
-2.55   STMN1      NM_005563   Stathmin;STMN1;ortholog
5.40    STOML2     NM_013442                                   structural
                               Stomatin-like protein 2;STOML2;orthologconstituent of cytoskeleton
2.91    STOX2      XM_048721   Storkhead-box protein 2;STOX2;ortholog
2.26    STX12      NM_177424   Syntaxin-12;STX12;ortholog SNAP receptor activity
4.89    STX17      NM_017919   Syntaxin-17;STX17;ortholog SNAP receptor activity
2.54    STX3A      NM_004177   Syntaxin-3;STX3;ortholog        SNAP receptor activity
2.50    STYX       NM_145251                                   phosphoprotein phosphatase
                               Serine/threonine/tyrosine-interacting protein;STYX;ortholog activity;phosphopro
-3.45   STYXL1     NM_016086                                   phosphoprotein phosphatase activity;phosphopro
                               Serine/threonine/tyrosine-interacting-like protein 1;STYXL1;ortholog
-2.29   SUB1       NM_006713                                   transcription coactivator p15;SUB1;ortholog
                               Activated RNA polymerase II transcriptional factor activity;transcription factor act
2.01    SULF1     NM_015170                                     hydrolase activity
                              Extracellular sulfatase Sulf-1;SULF1;ortholog
4.45    SUPT3H    NM_003599                                     transcription factor activity;transcription factor act
                              Transcription initiation protein SPT3 homolog;SUPT3H;ortholog
3.57    SURB7     NM_004264                                      transcription subunit 21;MED21;ortholog
                              Mediator of RNA polymerase IItranscription factor activity;transcription factor act
2.69    SUV39H1   NM_003173                                     methyltransferase activity;DNA binding
                              Histone-lysine N-methyltransferase SUV39H1;SUV39H1;ortholog
-2.36   SVOP      NM_018711                                     carbohydrate transmembrane transporter activity
                              Synaptic vesicle 2-related protein;SVOP;ortholog
-3.13   SYMPK     NM_004819   Symplekin;SYMPK;ortholog
-2.21   SYNCRIP   NM_006372                                     structural constituent of ribosome;mRNA binding
                              Heterogeneous nuclear ribonucleoprotein Q;SYNCRIP;ortholog
2.62    SYP       NM_003179   Synaptophysin;SYP;ortholog
-2.98   TACSTD2   NM_002353                                     receptor activity
                              Tumor-associated calcium signal transducer 2;TACSTD2;ortholog
2.62    TAF1B     NM_005680   TATA box-binding protein-associated factor RNA polymerase I subunit B;TAF1B
-2.64   TAS2R42   NM_181429   Taste receptor type 2 member 42;TAS2R42;ortholog
2.57    TBR1      NM_006593                                     transcription factor activity;transcription factor act
                              T-box brain protein 1;TBR1;ortholog
-3.31   TCEAL1    NM_004780                                     A protein-like 1;TCEAL1;ortholog
                              Transcription elongation factor transcription factor activity;transcription factor act
4.56    TCEB1     NM_005648                                     B polypeptide 1;TCEB1;ortholog
                              Transcription elongation factor enzyme activator activity
2.52    TCEB2     NM_007108                                     B polypeptide 2;TCEB2;ortholog
                              Transcription elongation factor transcription factor activity;transcription factor act
3.48    TCEB3B    NM_016427                                     transcription factor A2;TCEB3B;ortholog
                              RNA polymerase II transcription factor SIII subunitactivity;transcription factor act
4.66    TCF19     NM_007109   Transcription factor 19;TCF19;ortholog
-2.42   TDRD1     NM_198795                                     nuclease activity;nucleic acid binding
                              Tudor domain-containing protein 1;TDRD1;ortholog
-2.48   TDRD3     NM_030794   Tudor domain-containing protein 3;TDRD3;ortholog
2.54    TEAD4     NM_003213                                       TEF-3;TEAD4;ortholog
                              Transcriptional enhancer factortranscription factor activity;transcription factor act
-2.16   TEDDM1    NM_172000   Transmembrane epididymal protein 1;TEDDM1;ortholog
3.57    TEGT      NM_003217   Bax inhibitor 1;TMBIM6;ortholog
-2.94   TENC1     NM_015319                                     structural constituent of cytoskeleton;actin binding
                              Tensin-like C1 domain-containing phosphatase;TENC1;ortholog
2.61    TENS1     NM_022748   Tensin-3;TNS3;ortholog            phosphoprotein phosphatase activity;phosphopro
2.65    TERF2IP   NM_018975                                     nucleic acid binding
                              Telomeric repeat-binding factor 2-interacting protein 1;TERF2IP;ortholog
-2.04   TESK1     NM_006285                                     protein kinase activity
                              Dual specificity testis-specific protein kinase 1;TESK1;ortholog
2.44    TEX11     NM_031276   Testis-expressed sequence 11 protein;TEX11;ortholog
-2.74   TF        NM_001063   Serotransferrin;TF;ortholog       serine-type peptidase activity
2.42    TFDP1     NM_007111                                     transcription
                              Transcription factor Dp-1;TFDP1;ortholog factor activity;transcription factor act
-2.57   TFG       NM_006070   Protein TFG;TFG;ortholog
3.60    TGFB2     NM_003238                                     growth factor activity
                              Transforming growth factor beta-2;TGFB2;ortholog
-2.70   TGM1      NM_000359                                     acyltransferase K;TGM1;ortholog
                              Protein-glutamine gamma-glutamyltransferase activity
3.95    TGM6      NM_198994                                     acyltransferase 6;TGM6;ortholog
                              Protein-glutamine gamma-glutamyltransferase activity
-2.13   THAP3     NM_138350                                     nucleic acid binding
                              THAP domain-containing protein 3;THAP3;ortholog
-2.67   THRA      NM_003250                                     ligand-dependent
                              Thyroid hormone receptor alpha;THRA;ortholog nuclear receptor activity;transcr
2.64    THRAP2    NM_015335   Mediator of RNA polymerase II transcription subunit 13-like;MED13L;ortholog
-2.43   THRAP3    NM_005119                                     receptor activity;transcription factor
                              Thyroid hormone receptor-associated protein 3;THRAP3;ortholog activity;DNA p
7.69    THRAP4    NM_014815                                      transcription subunit 24;MED24;ortholog
                              Mediator of RNA polymerase IIreceptor activity
4.15    THSD1     NM_018676   Thrombospondin type-1 domain-containing protein 1;THSD1;ortholog
-2.98   TIPARP    NM_015508                                     nucleic acid binding
                              TCDD-inducible poly [ADP-ribose] polymerase;TIPARP;ortholog
-2.48   TITF1     NM_003317                                     transcription factor activity;transcription factor act
                              Homeobox protein Nkx-2.1;NKX2-1;ortholog
2.99    TJP3      NM_014428   Tight junction protein ZO-3;TJP3;ortholog
4.17    TK2       NM_004614                                     nucleotide kinase
                              Thymidine kinase 2, mitochondrial;TK2;ortholog activity
-2.58   TKTL1     NM_012253                                     transketolase
                              Transketolase-like protein 1;TKTL1;ortholog activity
-2.50   TKTL2     NM_032136                                     transketolase
                              Transketolase-like protein 2;TKTL2;ortholog activity
2.47    TLE4      NM_007005                                     transcription factor
                              Transducin-like enhancer protein 4;TLE4;ortholog activity;transcription factor act
-2.45   TLL1      NM_012464                                     oxidoreductase activity;serine-type peptidase acti
                              Tolloid-like protein 1;TLL1;ortholog
-2.33   TLR9      NM_017442   Toll-like receptor 9;TLR9;orthologreceptor activity
-2.15   TLX3      NM_021025                                     transcription factor activity;transcription factor act
                              T-cell leukemia homeobox protein 3;TLX3;ortholog
4.10    TM4SF1      NM_014220   Transmembrane 4 L6 family member 1;TM4SF1;ortholog
2.71    TMEM10      NM_033207   Opalin;OPALIN;ortholog
4.21    TMEM108     NM_023943   Transmembrane protein 108;TMEM108;ortholog
-2.12   TMEM134     NM_025124   Transmembrane protein 134;TMEM134;ortholog
-2.12   TMEM14B     NM_030969   Transmembrane protein 14B;TMEM14B;ortholog
3.02    TMEM16B     NM_020373   Anoctamin-2;ANO2;ortholog
-2.39   TMEM177     NM_030577   Transmembrane protein 177;TMEM177;ortholog
3.62    TMEM186     NM_015421   Transmembrane protein 186;TMEM186;ortholog
2.54    TMEM2       NM_013390   Transmembrane protein 2;TMEM2;ortholog
-2.52   TMEM33      NM_018126   Transmembrane protein 33;TMEM33;ortholog
2.53    TMEM35      NM_021637   Transmembrane protein 35;TMEM35;ortholog
3.58    TMEM85      NM_016454   Transmembrane protein 85;TMEM85;ortholog
3.45    TMPRSS2     NM_005656                                    serine-type peptidase activity
                                Transmembrane protease, serine 2 catalytic chain;TMPRSS2;ortholog
4.84    TMPRSS4     NM_019894                                    serine-type peptidase activity
                                Transmembrane protease, serine 4;TMPRSS4;ortholog
-2.42   TNA         NM_003278   Tetranectin;CLEC3B;ortholog extracellular matrix structural constituent
-2.90   TNFRSF10D   NM_003840                                     superfamily member 10D;TNFRSF10D;ortholog
                                Tumor necrosis factor receptorcytokine receptor activity;tumor necrosis factor re
-2.47   TNFRSF17    NM_001192                                     superfamily member 17;TNFRSF17;ortholog
                                Tumor necrosis factor receptorcytokine receptor activity
-2.38   TNFRSF1A    NM_001065                                    cytokine receptor activity;tumor
                                Tumor necrosis factor-binding protein 1;TNFRSF1A;ortholog necrosis factor re
-2.45   TNFRSF9     NM_001561                                     superfamily member 9;TNFRSF9;ortholog
                                Tumor necrosis factor receptorreceptor activity
3.33    TNNI1       NM_003281                                    structural constituent of cytoskeleton;actin binding
                                Troponin I, slow skeletal muscle;TNNI1;ortholog
-2.32   TNPO2       NM_013433   Transportin-2;TNPO2;ortholog transmembrane transporter activity
4.62    TOB2        NM_016272   Protein Tob2;TOB2;ortholog
-2.66   TOCA1       NM_017737                                    structural constituent of cytoskeleton;receptor bin
                                Formin-binding protein 1-like;FNBP1L;ortholog
-2.44   TOE1        NM_025077   Target of EGR1 protein 1;TOE1;ortholog
-2.49   TOM1        NM_005488                                    transmembrane transporter activity
                                Target of Myb protein 1;TOM1;ortholog
3.70    TOMM7       NM_019059                                    transmembrane transporter activity
                                Mitochondrial import receptor subunit TOM7 homolog;TOMM7;ortholog
4.32    TOP1        NM_003286   DNA topoisomerase 1;TOP1;orthologDNA topoisomerase activity;DNA topoisomerase
3.74    TP53BP2     NM_005426                                    protein binding
                                Apoptosis-stimulating of p53 protein 2;TP53BP2;ortholog
-2.34   TP53I3      NM_004881                                    oxidoreductase activity
                                Putative quinone oxidoreductase;TP53I3;ortholog
3.11    TP53INP1    NM_033285   Tumor protein p53-inducible nuclear protein 1;TP53INP1;ortholog
-3.23   TP63        NM_003722   Tumor protein 63;TP63;ortholog   transcription factor activity;transcription factor act
-2.35   TPD52L1     NM_003287   Tumor protein D53;TPD52L1;ortholog
3.27    TPD52L2     NM_003288   Tumor protein D54;TPD52L2;ortholog
3.75    TPK1        NM_022445                                    kinase activity
                                Thiamin pyrophosphokinase 1;TPK1;ortholog
-2.68   TPR         NM_003292   Nucleoprotein TPR;TPR;ortholog   transmembrane receptor protein kinase activity;tr
-3.24   TPT1        NM_003295                                    structural constituent of
                                Translationally-controlled tumor protein;TPT1;ortholog cytoskeleton;microtubule
2.70    TRAM2       NM_012288   Translocation-associated membrane protein 2;TRAM2;ortholog
-2.09   TRAPPC2L    NM_016209   Trafficking protein particle complex subunit 2-like protein;TRAPPC2L;ortholog
-2.15   TRIM41      NM_033549                                    ubiquitin-protein ligase
                                Tripartite motif-containing protein 41;TRIM41;ortholog activity
2.76    TRIM58      NM_015431   Tripartite motif-containing protein 58;TRIM58;ortholog activity
                                                                 ubiquitin-protein ligase
3.18    TRIM62      NM_018207                                    ubiquitin-protein ligase
                                Tripartite motif-containing protein 62;TRIM62;ortholog activity
-2.14   TRIP10      NM_004240                                    structural constituent of cytoskeleton;receptor bin
                                Cdc42-interacting protein 4;TRIP10;ortholog
2.39    TRMT1       NM_018006                                    RNA methyltransferase activity;nucleic acid bindin
                                Mitochondrial tRNA-specific 2-thiouridylase 1;TRMU;ortholog
-2.42   TRPC3       NM_003305                                    ion channel activity
                                Short transient receptor potential channel 3;TRPC3;ortholog
-2.20   TRPC5       NM_012471                                    ion channel activity
                                Short transient receptor potential channel 5;TRPC5;ortholog
-2.26   TRPS1       NM_014112                                    nuclease activity;transcription factor activity;trans
                                Zinc finger transcription factor Trps1;TRPS1;ortholog
2.83    TSARG6      NM_153614   DnaJ homolog subfamily B member 13;DNAJB13;ortholog
2.77    TSGA13      NM_052933   Testis-specific gene 13 protein;TSGA13;ortholog
-2.27   TSGA14      NM_018718   Centrosomal protein of 41 kDa;TSGA14;ortholog
2.37    TSPAN33      NM_178562   Tetraspanin-33;TSPAN33;ortholog  receptor binding
-2.32   TSPAN9       NM_031285   Tetraspanin-9;TSPAN9;ortholog    receptor binding
4.02    TSRC1        NM_019032   ADAMTS-like protein 4;ADAMTSL4;ortholog
2.22    TST          NM_003312                                    transferase
                                 Thiosulfate sulfurtransferase;TST;ortholog activity
2.39    TTC11        NM_016068   Mitochondrial fission 1 protein;FIS1;ortholog
3.52    TTC15        NM_016030                                    peptidase activity
                                 Tetratricopeptide repeat protein 15;TTC15;ortholog
2.35    TTC9         XM_027236                                    isomerase activity
                                 Tetratricopeptide repeat protein 9A;TTC9;ortholog
-2.41   TTID         NM_006790   Myotilin;MYOT;ortholog           structural constituent of cytoskeleton
-3.29   TTLL6        NM_173623                                    ligase activity;structural constituent of cytoskeleto
                                 Tubulin polyglutamylase TTLL6;TTLL6;ortholog
3.75    TUBA3        NM_006009                                    structural constituent of cytoskeleton
                                 Tubulin alpha-1A chain;TUBA1A;ortholog
-2.41   TUBA3E       NM_207312                                    structural constituent of cytoskeleton
                                 Tubulin alpha-3E chain;TUBA3E;ortholog
3.30    TUBG2        NM_016437                                    structural
                                 Tubulin gamma-2 chain;TUBG2;ortholog constituent of cytoskeleton
2.76    TULP1        NM_003322   Tubby-related protein 1;TULP1;ortholog
2.08    TUSC3        NM_006765                                    transferase activity,
                                 Tumor suppressor candidate 3;TUSC3;ortholog transferring glycosyl groups
-2.34   TWIST2       NM_057179                                    transcription factor activity;transcription factor act
                                 Twist-related protein 2;TWIST2;ortholog
2.36    TYMS         NM_001071                                    methyltransferase activity
                                 Thymidylate synthase;TYMS;ortholog
8.33    UBCE7IP5     NM_014948   RING finger protein 37;UBOX5;ortholog
-2.35   UBE1DC1      NM_024818                                    ligase activity
                                 Ubiquitin-like modifier-activating enzyme 5;UBA5;ortholog
2.87    UBE1L        NM_003335                                    ligase activity
                                 Ubiquitin-like modifier-activating enzyme 7;UBA7;ortholog
-2.32   UBE2K        NM_005339                                    ligase activity
                                 Ubiquitin-conjugating enzyme E2 K;UBE2K;ortholog
2.53    UBE2R2       NM_017811                                    ligase activity
                                 Ubiquitin-conjugating enzyme E2 R2;UBE2R2;ortholog
-2.13   UBE3B        NM_130466                                    ubiquitin-protein
                                 Ubiquitin-protein ligase E3B;UBE3B;ortholog ligase activity
3.21    UBQLN1       NM_013438   Ubiquilin-1;UBQLN1;ortholog
-2.67   UBXN2B       XM_059929   UBX domain-containing protein 2B;UBXN2B;ortholog
2.89    UDPGT,UGT1   NM_007120                                    transferase activity, transferring glycosyl groups
                                 UDP-glucuronosyltransferase 1-5;UGT1A5;ortholog
2.23    UFSP1        XM_380026   Inactive Ufm1-specific protease 1;UFSP1;ortholog
2.66    UGT1A5       NM_019078                                    transferase activity, transferring glycosyl groups
                                 UDP-glucuronosyltransferase 1-5;UGT1A5;ortholog
5.90    UHRF1        NM_013282                                    transcription factor activity;transcription factor act
                                 E3 ubiquitin-protein ligase UHRF1;UHRF1;ortholog
-2.44   UIMC1        NM_016290   Ubiquitin interaction motif-containing protein 1;UIMC1;ortholog
4.08    UMPS         NM_000373   Orotidine 5'-phosphate decarboxylase;UMPS;ortholog
2.59    UNC5C        NM_003728                                    receptor activity
                                 Netrin receptor UNC5C;UNC5C;ortholog
-2.39   UNG2         NM_021147   Cyclin-O;CCNO;ortholog           nucleic acid binding;protein binding;kinase activa
2.69    UPK2         NM_006760   Uroplakin-2;UPK2;ortholog
3.72    UPP1         NM_003364                                    phosphorylase activity
                                 Uridine phosphorylase 1;UPP1;ortholog
-2.46   UPRT         NM_145052                                    nucleotide kinase
                                 Uracil phosphoribosyltransferase;UPRT;ortholog activity;transferase activity, tran
2.78    UQCRB        NM_006294                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 7;UQCRB;ortholog
4.18    UQCRFS1      NM_006003                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 11;UQCRFS1;ortholog
4.93    UQCRH        NM_006004                                    oxidoreductase activity
                                 Cytochrome b-c1 complex subunit 6, mitochondrial;UQCRH;ortholog
2.27    USE1         NM_018467   Vesicle transport protein USE1;USE1;ortholog
5.51    USH3A        NM_052995   Clarin-1;CLRN1;ortholog
-2.94   USP1         NM_003368                                    cysteine-type peptidase
                                 Ubiquitin carboxyl-terminal hydrolase 1;USP1;ortholog activity
8.15    USP10        NM_005153                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 10;USP10;ortholog
-2.22   USP18        NM_017414                                    cysteine-type peptidase activity
                                 Ubl carboxyl-terminal hydrolase 18;USP18;ortholog
-2.09   USP2         NM_004205                                    cysteine-type peptidase
                                 Ubiquitin carboxyl-terminal hydrolase 2;USP2;ortholog activity
4.28    USP20        NM_006676                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 20;USP20;ortholog
-3.02   USP21        NM_012475                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 21;USP21;ortholog
2.24    USP24        XM_165973                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 24;USP24;ortholog
-3.24   USP33        NM_015017                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 33;USP33;ortholog
5.40    USP35        XM_290527                                    cysteine-type peptidase activity
                                 Ubiquitin carboxyl-terminal hydrolase 35;USP35;ortholog
-2.22   USP44      NM_032147                                     cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 44;USP44;ortholog
7.92    USP46      NM_022832                                     cysteine-type peptidase activity
                               Ubiquitin carboxyl-terminal hydrolase 46;USP46;ortholog
-2.25   USP5       NM_003481                                     cysteine-type peptidase
                               Ubiquitin carboxyl-terminal hydrolase 5;USP5;ortholog activity
-2.19   USP52      NM_014871                                     cysteine-type peptidase activity;exoribonuclease
                               PAB-dependent poly(A)-specific ribonuclease subunit 2;PAN2;ortholog
3.72    VCX3       NM_016379   Variable charge X-linked protein 3;VCX3A;ortholog
2.96    VDRIP      NM_014166                                      transcription subunit 4;MED4;ortholog
                               Mediator of RNA polymerase IItranscription factor activity;transcription factor act
-2.67   VHL        NM_000551                                     ligase activity
                               Von Hippel-Lindau disease tumor suppressor;VHL;ortholog
2.99    VILL       NM_015873   Villin-like protein;VILL;ortholog structural constituent of cytoskeleton;actin binding
-2.47   VIM        NM_003380   Vimentin;VIM;ortholog             structural constituent of cytoskeleton
3.29    VNN2       NM_004665                                     hydrolase activity
                               Vascular non-inflammatory molecule 2;VNN2;ortholog
3.51    VNN3       NM_018399                                     hydrolase activity
                               Vascular non-inflammatory molecule 3;VNN3;ortholog
-2.68   VPS16      NM_022575   Vacuolar protein sorting-associated protein 16 homolog;VPS16;ortholog
-2.26   VPS29      NM_016226   Vacuolar protein sorting-associated protein 29;VPS29;ortholog
-2.51   VPS35      NM_018206   Vacuolar protein sorting-associated protein 35;VPS35;ortholog
-2.18   VPS52      NM_022553   Vacuolar protein sorting-associated protein 52 homolog;VPS52;ortholog
-2.20   VSTM1      NM_198481                                     receptor activity
                               V-set and transmembrane domain-containing protein 1;VSTM1;ortholog
2.79    VSTM2B     XM_292785                                     receptor activity
                               V-set and transmembrane domain-containing protein 2B;VSTM2B;ortholog
-2.90   VWA1       NM_022834   von Willebrand factor A domain-containing protein 1;VWA1;ortholog
-2.63   VWF        NM_000552   von Willebrand antigen 2;VWF;ortholog
-2.28   WAC        NM_016628   WW domain-containing adapter protein with coiled-coil;WAC;ortholog
-2.62   WDR20      NM_144574   WD repeat-containing protein 20;WDR20;ortholog
-2.54   WDR88      NM_173479   WD repeat-containing protein 88;WDR88;ortholog
-2.44   WNT10B     NM_003394   Protein Wnt-10b;WNT10B;ortholog   receptor binding
-2.92   WNT16      NM_016087   Protein Wnt-16;WNT16;ortholog     receptor binding
2.41    WNT4       NM_030761   Protein Wnt-4;WNT4;ortholog receptor binding
-2.54   XK         NM_021083   Membrane transport protein XK;XK;ortholog
2.01    XKRX       NM_212559   XK-related protein 2;XKRX;ortholog
2.34    XPA        NM_000380                                     damaged cells;XPA;ortholog
                               DNA repair protein complementing XP-A DNA binding
-2.35   XPO6       NM_015171   Exportin-6;XPO6;ortholog
3.35    YAF2       NM_005748                                     transcription factor activity;transcription factor act
                               YY1-associated factor 2;YAF2;ortholog
-2.62   YARS2      NM_015936                                     aminoacyl-tRNA ligase activity;nucleic acid bindin
                               Tyrosyl-tRNA synthetase, mitochondrial;YARS2;ortholog
4.98    YEATS2     NM_018023                                     transcription factor activity;chromatin binding;tran
                               YEATS domain-containing protein 2;YEATS2;ortholog
-2.23   YIPF6      NM_173834   Protein YIPF6;YIPF6;ortholog
4.04    YRDC       NM_024640   YrdC domain-containing protein, mitochondrial;YRDC;ortholog
-3.49   ZBED5      NM_021211                                     transcription factor activity;transcription factor act
                               Zinc finger BED domain-containing protein 5;ZBED5;ortholog
2.27    ZBTB33     NM_006777                                     transcription factor
                               Transcriptional regulator Kaiso;ZBTB33;ortholog activity;transcription factor act
2.65    ZC3H12D    XM_291154                                     nucleic acid binding
                               Zinc finger CCCH domain-containing protein 12D;ZC3H12D;ortholog
4.53    ZCCHC8     NM_017612                                     nucleic acid binding
                               Zinc finger CCHC domain-containing protein 8;ZCCHC8;ortholog
-3.15   ZDHHC12    NM_032799   Probable palmitoyltransferase ZDHHC12;ZDHHC12;ortholog
-2.48   ZDHHC6     NM_022494   Probable palmitoyltransferase ZDHHC6;ZDHHC6;ortholog
-2.23   ZFP276     NM_152287                                     transcription factor activity;transcription factor act
                               Zinc finger protein 276;ZNF276;ortholog
-1.96   ZFYVE28    XM_035371                                     transcription 28;ZFYVE28;ortholog
                               Zinc finger FYVE domain-containing protein factor activity;transcription factor act
4.39    ZMPSTE24   NM_005857                                     metallopeptidase activity
                               CAAX prenyl protease 1 homolog;ZMPSTE24;ortholog
3.94    ZMYND11    NM_006624                                     transcription factor activity;transcription
                               Zinc finger MYND domain-containing protein 11;ZMYND11;ortholog factor act
2.45    ZMYND19    NM_138462                                     transcription factor activity;transcription
                               Zinc finger MYND domain-containing protein 19;ZMYND19;ortholog factor act
3.86    ZNF124     NM_003431   Zinc finger protein 124;ZNF124;ortholog
-2.38   ZNF161     NM_007146                                       1;VEZF1;ortholog
                               Vascular endothelial zinc fingertranscription factor activity;transcription factor act
2.53    ZNF174     NM_003450                                     transcription factor activity;transcription factor act
                               Zinc finger protein 174;ZNF174;ortholog
2.70    ZNF248     NM_021045                                     transcription factor activity;transcription factor act
                               Zinc finger protein 248;ZNF248;ortholog
-2.34   ZNF281    NM_012482                                  transcription factor activity;transcription factor act
                              Zinc finger protein 281;ZNF281;ortholog
-2.42   ZNF288    NM_015642                                  transcription factor activity;transcription
                              Zinc finger and BTB domain-containing protein 20;ZBTB20;ortholog factor act
-2.35   ZNF289    NM_032389                                  nucleic acid binding;protein binding;small
                              ADP-ribosylation factor GTPase-activating protein 2;ARFGAP2;ortholog GTPas
-2.62   ZNF300    NM_052860                                  transcription factor activity;transcription factor act
                              Zinc finger protein 300;ZNF300;ortholog
-2.15   ZNF326    NM_182975   Zinc finger protein 326;ZNF326;ortholog
3.08    ZNF341    NM_032819                                  transcription factor activity;transcription factor act
                              Zinc finger protein 341;ZNF341;ortholog
2.42    ZNF385D   NM_024697   Zinc finger protein 385D;ZNF385D;ortholog
                                                             nuclease activity;transcription factor activity;trans
-2.28   ZNF397    NM_032347                                  transcription factor activity;transcription factor act
                              Zinc finger protein 397;ZNF397;ortholog
2.97    ZNF406    NM_020863                                  transcription factor activity;transcription factor act
                              Zinc finger protein ZFAT;ZFAT;ortholog
-3.94   ZNF42     NM_003422                                  transcription factor activity;transcription factor act
                              Myeloid zinc finger 1;MZF1;ortholog
-2.14   ZNF44     NM_016264                                  transcription factor activity;transcription factor act
                              Zinc finger protein 44;ZNF44;ortholog
2.99    ZNF446    NM_017908   Zinc finger protein 446;ZNF446;ortholog
                                                             transcription factor activity;transcription factor act
-2.35   ZNF454    NM_182594                                  transcription factor activity;transcription factor act
                              Zinc finger protein 454;ZNF454;ortholog
-2.18   ZNF493    NM_175910                                  transcription factor activity;transcription factor act
                              Zinc finger protein 493;ZNF493;ortholog
-2.58   ZNF501    NM_145044                                  transcription factor activity;transcription factor act
                              Zinc finger protein 501;ZNF501;ortholog
-2.47   ZNF529    NM_020951                                  transcription factor activity;transcription factor act
                              Zinc finger protein 529;ZNF529;ortholog
2.05    ZNF537    NM_020856                                  transcription factor activity;transcription factor act
                              Teashirt homolog 3;TSHZ3;ortholog
3.19    ZNF609    XM_042833   Zinc finger protein 609;ZNF609;ortholog
-2.42   ZNF621    NM_198484                                  transcription factor activity;transcription factor act
                              Zinc finger protein 621;ZNF621;ortholog
2.23    ZNF643    NM_023070   Zinc finger protein 643;ZNF643;ortholog
                                                             transcription factor activity;transcription factor act
5.53    ZNF654    NM_018293                                  nuclease
                              Zinc finger protein 654;ZNF654;ortholog activity;transcription factor activity;trans
2.08    ZNF670    NM_033213   Zinc finger protein 670;ZNF670;ortholog
                                                             transcription factor activity;transcription factor act
-2.28   ZNF673    NM_017776   Protein ZNF673;ZNF673;ortholog transcription factor activity;transcription factor act
2.68    ZNF701    NM_018260   Zinc finger protein 701;ZNF701;ortholog
                                                             transcription factor activity;transcription factor act
-2.48   ZNF747    NM_023931                                  transcription factor activity;transcription factor act
                              KRAB domain-containing protein ZNF747;ZNF747;ortholog
3.35    ZNF76     NM_003427                                  transcription factor activity;transcription factor act
                              Zinc finger protein 76;ZNF76;ortholog
2.44    ZNF765    NM_138372   Zinc finger protein 765;ZNF765;ortholog
                                                             transcription factor activity;transcription factor act
2.18    ZNF813    XM_064903                                  transcription factor activity;transcription factor act
                              Zinc finger protein 813;ZNF813;ortholog
-2.80   ZNFN1A3   NM_012481                                  transcription factor activity;transcription factor act
                              Zinc finger protein Aiolos;IKZF3;ortholog
2.36    ZSCAN18   NM_023926                                  transcription factor activity;transcription factor act
                              Zinc finger and SCAN domain-containing protein 18;ZSCAN18;ortholog
2.25    ZSWIM2    NM_182521                                  transcription 2;ZSWIM2;ortholog
                              Zinc finger SWIM domain-containing proteinfactor activity;transcription factor act
2.85    ZYG11B    XM_038291   Protein zyg-11 homolog B;ZYG11B;ortholog
            GO Biological Process             GO Cellular Component            Panther Protein Class
                                              microtubule                      non-motor microtubule binding protein
            cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
            intracellular protein transport;nuclear transport
            cellular amino acid catabolic process                              dehydrogenase;reductase
            immune system process;extracellular transport                      ATP-binding cassette (ABC) transporter
            immune system process;extracellular transport;response to toxin    ATP-binding cassette (ABC) transporter
            lipid transport;lipid metabolic process                            transporter
                                                                               hydrolase
            immune system process;proteolysis;response to toxin                serine protease;serine protease
            immune system process;proteolysis;response to toxin                serine protease;serine protease
                                                                               hydrolase
                                              actin cytoskeleton
            cell motion;ectoderm development;nervous system development        structural protein;actin family cytoskeletal protein
            protein metabolic process                                          transferase
                                                                               dehydrogenase
            respiratory electron transport chain;acyl-CoA metabolic process;acyl-CoA metabolic process
            acyl-CoA metabolic process;acyl-CoA metabolic process              esterase
                                                                               protein phosphatase;protein phosphatase
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
                                                                               phosphatase;phosphatase
            cation transport;phosphate metabolic process;protein amino acid phosphorylation;proteolysis;mesoderm development;skeletal
                                                                               phosphatase;phosphatase
            fatty acid metabolic process                                       ligase
                                              actin cytoskeleton               actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;cellular com
                                              actin cytoskeleton               actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;cellular com
                                              actin cytoskeleton               actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;cellular com
                                              actin cytoskeleton               non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                              actin cytoskeleton               actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;cellular com
                                              actin cytoskeleton               actin and actin related protein
            intracellular protein transport;exocytosis;endocytosis;mitosis;cytokinesis;mitosis;cellular component morphogenesis;cellular com
                                                                               serine/threonine protein kinase receptor;TGF-beta receptor;serin
            cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protein amino
            cellular amino acid biosynthetic process;proteolysis               metalloprotease;metalloprotease
            purine base metabolic process                                      deaminase
                                                                               metalloprotease;metalloprotease
            fertilization;signal transduction;cell-matrix adhesion;cell-cell adhesion;proteolysis;signal transduction;cell-matrix adhesion;cell-c
                                                                               metalloprotease;metalloprotease
            signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
                                                                               metalloprotease;metalloprotease
            signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
            cellular amino acid biosynthetic process                           decarboxylase
            protein complex assembly          actin cytoskeleton               non-motor actin binding protein
            carbohydrate metabolic process                                     dehydrogenase;reductase
            carbohydrate metabolic process                                     dehydrogenase;reductase
            cellular amino acid metabolic process                              oxidoreductase
                                                                               receptor
            cell surface receptor linked signal transduction;fatty acid metabolic process;cell surface receptor linked signal transduction
tein;ADNP;ortholog
            proteolysis                                                        serine protease inhibitor

                                                                          transmembrane receptor regulatory/adaptor protein;immunoglobu
             immune system process;cell surface receptor linked signal transduction;cell-cell adhesion;cell surface receptor linked signal tra
             glycogen metabolic process                                   glycosyltransferase;glycosidase
             phospholipid metabolic process                               acyltransferase
             cellular amino acid metabolic process                        transaminase
             purine base metabolic process                                hydrolase
             visual perception;sensory perception                         chaperone
                                                                          nucleotide kinase;nucleotide kinase
             purine base metabolic process;pyrimidine base metabolic process
             metabolic process                                            reductase
             porphyrin metabolic process                                  transferase
              porphyrin metabolic process                                  transferase
              metabolic process                                            dehydrogenase
              metabolic process                                            dehydrogenase
              metabolic process                                            dehydrogenase
              glycolysis                                                   aldolase
              DNA repair
              protein targeting;signal transduction;signal transduction    enzyme modulator
                                                                           membrane traffic protein
              intracellular protein transport;ectoderm development;nervous system development
 ion candidate gene 8 protein;ALS2CR8;ortholog
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;mesoderm development;skeletal system development
              polysaccharide metabolic process                             deacetylase
              purine base metabolic process                                deaminase
              cellular amino acid catabolic process                        dehydrogenase
              cell cycle;proteolysis;cell cycle                            ligase

KRD10;ortholog
KRD31;ortholog
 osphatase inhibitor activity;phosphatase regulator activity                 phosphatase inhibitor
             proteolysis                                                     metalloprotease;metalloprotease
             intracellular protein transport;vesicle-mediated transport      membrane traffic protein
                                              microtubule                    non-motor microtubule binding protein
             apoptosis;cell cycle;cell surface receptor linked signal transduction;apoptosis;cell adhesion;cell cycle;cell surface receptor linke
             protein amino acid acetylation;proteolysis                      serine protease;serine protease
             DNA repair                                                      endodeoxyribonuclease;exodeoxyribonuclease;nuclease

              lipid transport;lipid metabolic process                         transporter;apolipoprotein

             lipid transport;cholesterol metabolic process                   transporter;apolipoprotein
             lipid transport;cholesterol metabolic process                   transporter;apolipoprotein
             lipid transport;cholesterol metabolic process                   transporter;apolipoprotein
             transport                                                       transporter
             metabolic process                                               reductase
             intracellular protein transport;vesicle-mediated transport      small GTPase
                                                                             G-protein modulator
             cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                             small GTPase
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
             cell motion                                                     G-protein modulator
mall GTPase regulator activity                                               G-protein modulator
                                              cytoskeleton
             intracellular signaling cascade;intracellular signaling cascade cytoskeletal protein
             intracellular signaling cascade;intracellular signaling cascade signaling molecule;G-protein modulator
             intracellular signaling cascade;intracellular signaling cascade signaling molecule;G-protein modulator
                                                                             small
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis GTPase
                                              actin cytoskeleton             actin family cytoskeletal protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                              actin cytoskeleton             actin family cytoskeletal protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             cell motion                      actin cytoskeleton             actin family cytoskeletal protein


                                                                          hydrolase
              sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
                                                                          hydrolase
              sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
              cellular amino acid metabolic process                       metalloprotease;deacetylase;metalloprotease
                                                                          hydroxylase
              transmembrane receptor protein tyrosine kinase signaling pathway;protein modification process;transmembrane receptor prote
            protein modification process                                hydroxylase
                                                                        hydrolase
            protein metabolic process;cellular component morphogenesis;cellular component morphogenesis;cellular component morphog
            protein metabolic process                                   hydrolase
            regulation of transcription from RNA polymerase II promoter CREB transcription factor;nucleic acid binding
n 2;ATF7IP2;ortholog
                                                                         repair;protein amino acid phosphorylation;cell cycle;response to
            immune system process;induction of apoptosis;cell cycle;DNAnucleotide kinase;non-receptor serine/threonine protein kinase;nu
            cation transport;lipid transport;lipid metabolic process    transporter;hydrolase
            cation transport;cellular calcium ion homeostasis           cation transporter;ion channel;hydrolase
            cation transport                                            ATP synthase

                                               proton-transporting ATP nucleic acid metabolic process
                                                                               ATP synthase;ion channel;hydrolase
             cation transport;nucleobase, nucleoside, nucleotide andsynthase complex
                                               proton-transporting ATP nucleic acid transport;nucleobase, nucleoside, nucleotide and nucleic a
                                                                               ATP synthase;ion channel;hydrolase
             cation transport;nucleobase, nucleoside, nucleotide andsynthase complex
             cation transport;purine base metabolic process                    ATP synthase;hydrolase
             cation transport;cellular calcium ion homeostasis                 cation transporter;ion channel;hydrolase
                                                                               transporter;hydrolase
             cation transport;lipid transport;lipid metabolic process;cellular calcium ion homeostasis
             neurological system process                                       RNA binding protein
             mitosis;protein amino acid phosphorylation;cytokinesis;mitosisnon-receptor serine/threonine protein kinase;non-receptor serine

                                                                          G-protein receptor protein signaling pathway;dorsal/ventral axis s
             G-protein coupled receptor protein signaling pathway;G-protein coupled modulator
             carbohydrate metabolic process                               glycosyltransferase
             regulation of transcription from RNA polymerase II promoter transcription factor;nucleic acid binding

             induction of apoptosis                                         signaling molecule
                                                                            homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;skeletal system d
                                                                            homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;skeletal system d
                                                                            signaling molecule
             gamete generation;induction of apoptosis;cell cycle;cell cycle;mesoderm development;hemopoiesis

                                            extracellular matrix         development;nervous system development
             cell adhesion;cell adhesion;ectoderm development;mesodermextracellular matrix glycoprotein
                                                                        esterase
             neurological system process;neuromuscular synaptic transmission;neuromuscular synaptic transmission

             protein metabolic process                                       translation initiation factor
                                              SNARE complex
             intracellular protein transport;vesicle-mediated transport      SNARE protein

                                             extracellular matrix             receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell-cell adhesion;cell surface receptor linked signal transduction;cell-cell adhes
             proteolysis                                                      ubiquitin-protein ligase


                                                                              membrane trafficking regulatory protein
              neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
                                                                              membrane trafficking regulatory protein
              neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
              negative regulation of apoptosis                                protease inhibitor
              neurological system process;induction of apoptosis
              neurological system process;induction of apoptosis
                                                                              serine/threonine protein kinase receptor;TGF-beta receptor;serin
              transmembrane receptor protein serine/threonine kinase signaling pathway;cytokine-mediated signaling pathway;protein amino
              apoptosis
protein 3-like;BNIP3L;ortholog
              induction of apoptosis                                          signaling molecule

             immune system process;proteolysis;response to toxin             serine protease;serine protease
             proteolysis                                                     ubiquitin-protein ligase
                                                                             zinc finger transcription cycle
              cell cycle;DNA repair;regulation of transcription from RNA polymerase II promoter;cell factor


              mitosis;DNA repair;mitosis;chromosome segregation               DNA helicase;helicase

              neurological system process;synaptic transmission;synaptic transmission
                                               plasma membrane                 transmembrane receptor regulatory/adaptor protein
              cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                               ubiquitin-protein ligase
              synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteolysis;signa
                                                                               DNA helicase;helicase
              regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
                                                                               hydrolase
              signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
                                                                               transcription factor
              transcription initiation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
              mesoderm development;mammary gland development
                                                                               non-receptor serine/threonine protein kinase;non-receptor serine
              mitosis;protein amino acid phosphorylation;mitosis;chromosome segregation;embryonic development
              coenzyme metabolic process;fatty acid metabolic process          ligase
              translation                                                      translation initiation factor;nuclease
              coenzyme metabolic process;fatty acid metabolic process          ligase


1;SYCE1;ortholog
SSF7;ortholog




ause currently there is support for the transcript but not for the protein.

ansporter activity                                                            transporter


                                                                               kinase modulator
              cell surface receptor linked signal transduction;cell surface receptor linked signal transduction




              carbohydrate transport;carbohydrate metabolic process           transporter;receptor




                                                                              kinase;kinase
erase activity;nucleic acid binding                                           RNA methyltransferase;RNA binding protein
              complement activation;proteolysis;blood coagulation             serine protease;serine protease;complement component
              complement activation;proteolysis;response to stimulus          serine protease;serine protease;complement component
              cellular amino acid catabolic process;proteolysis               protease;protease
                                                                               transcription cofactor
               cell cycle;DNA repair;regulation of transcription from RNA polymerase II promoter;cell cycle
               intracellular signaling cascade;intracellular signaling cascade




               protein modification process                                 methyltransferase
               embryonic development
                                                                            G-protein receptor protein
               G-protein coupled receptor protein signaling pathway;G-protein coupled coupled receptorsignaling pathway
               metabolic process                                            transfer/carrier protein




               ectoderm development;nervous system development               hydrolase




               cell cycle;DNA replication;cell cycle                         replication origin binding protein




                                                                           protein phosphatase;protein phosphatase
               transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto




y, transferring glycosyl groups                                              glycosyltransferase


C15;ortholog




omolog;RMND1;ortholog




                                                                             hydrolase




               protein modification process
M38B;ortholog

                                                                             calmodulin
              cell cycle;calcium-mediated signaling;cell cycle;calcium-mediated signaling
                                                                              potential propagation;cation transport;synaptic transmission;syna
              muscle contraction;neurotransmitter secretion;neuronal actionvoltage-gated calcium channel;voltage-gated ion channel
                                                                             voltage-gated calcium channel;voltage-gated ion channel
              neuronal action potential propagation;cation transport;cell communication;cell communication
                                                                              potential propagation;cation transport;synaptic transmission;syna
              muscle contraction;neurotransmitter secretion;neuronal actionvoltage-gated calcium channel;voltage-gated ion channel
                                                                              potential propagation;cation transport;synaptic transmission;syna
              muscle contraction;neurotransmitter secretion;neuronal actionvoltage-gated calcium channel;voltage-gated ion channel
                                                                             voltage-gated calcium channel;voltage-gated ion channel
              muscle contraction;neurological system process;cation transport;protein targeting;calcium-mediated signaling;calcium-mediate
ubunit;CACNG6;ortholog
              cation transport                                               voltage-gated calcium channel;voltage-gated ion channel
                                                                             acid phosphorylation;calcium-mediated signaling
              muscle contraction;calcium-mediated signaling;protein amino non-receptor serine/threonine protein kinase;non-receptor serine
              immune system process;defense response to bacterium            protease inhibitor;antibacterial response protein
                                              actin cytoskeleton             non-motor actin binding protein
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
              induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induc
              apoptosis;transcription from RNA polymerase II promoter
CARKD;ortholog
              neurological system process;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic transmissio
              apoptosis;proteolysis                                          cysteine protease;cysteine protease
              proteolysis                                                    cysteine protease inhibitor
              metabolic process                                              dehydrogenase;reductase
                                                                             chromatin/chromatin-binding protein
              apoptosis;regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture
 114;ortholog
 121;ortholog
 128;ortholog
 132;ortholog
 151;ortholog


74A;ortholog


                                                                           G-protein coupled receptor
               neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling
                                                                           chemokine
               immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
                                                                           chemokine
               immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
                                                                           chemokine
               macrophage activation;cytokine-mediated signaling pathway;cell-cell signaling;cell motion;cytokine-mediated signaling pathway
               spermatogenesis;mitosis;mitosis                             kinase activator
               mitosis;mitosis                                             kinase activator
               mitosis;mitosis                                             kinase activator
               mitosis;mitosis                                             kinase activator
                                              RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter;transc
               cell cycle;RNA elongation from nucleus                      transcription cofactor;kinase activator
                                              MHC protein defense
               antigen processing and presentation;cellularcomplex responseimmunoglobulin receptor superfamily;immunoglobulin receptor su

                                                                               receptor
               macrophage activation;extracellular transport;negative regulation of apoptosis
               lysosomal transport;intracellular protein transport;proteolysis membrane trafficking regulatory protein
                                                                               immunoglobulin receptor superfamily;immunoglobulin receptor ty
               immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein su
                                                                               membrane-bound
               B cell mediated immunity;cell adhesion;cell adhesion;cellular defense response signaling molecule;immunoglobulin receptor su
               mitosis;cytokinesis;mitosis     cytoskeleton                    small GTPase;cytoskeletal protein
               mitosis;protein metabolic process;mitosis                       ubiquitin-protein ligase
                                                                              protein phosphatase;protein phosphatase
              cell cycle;phosphate metabolic process;protein modification process;cell cycle
                                                                              protein phosphatase;protein phosphatase
              cell cycle;phosphate metabolic process;protein modification process;cell cycle
              mitosis;mitosis
                                                                              kinase activator;chaperone
              mitosis;signal transduction;protein folding;cytokinesis;mitosis;signal transduction;cellular component morphogenesis;cellular co
                                                                              small GTPase
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
              cell cycle;DNA replication;cell cycle                           replication origin binding protein
              cell cycle;cell cycle                                           transcription factor

                                                                                  cadherin
               signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                                  cadherin
               signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                                  cadherin
               sensory perception of sound;sensory perception;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ect
               mitosis;protein amino acid phosphorylation;mitosis                 non-receptor serine/threonine protein kinase;non-receptor serine
               mitosis;protein amino acid phosphorylation;mitosis                 non-receptor serine/threonine protein kinase;non-receptor serine
CDKN2A;ortholog
                                                                                  transcription factor;nucleic acid binding
               natural killer cell activation;apoptosis;regulation of transcription from RNA polymerase II promoter;mesoderm development;hem
n 1;CEND1;ortholog
                                                                                  nucleic acid binding;G-protein modulator
               G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad
               immune system process;response to toxin                            esterase
               immune system process;response to toxin                            esterase
               complement activation;proteolysis;response to stimulus             serine protease;serine protease;complement component
                                                 actin cytoskeleton               non-motor actin binding protein
               protein complex assembly;cellular component morphogenesis;cellular component morphogenesis;cellular component morphog
               spermatogenesis;female gamete generation                           peptide hormone
 ng protein 3, mitochondrial;CHCHD3;ortholog
                                                                                  non-receptor acid phosphorylation;meiosis;calcium-mediated sig
               immune system process;meiosis;calcium-mediated signaling;protein amino serine/threonine protein kinase;non-receptor serine
               phospholipid metabolic process                                     kinase;kinase
                                                 nucleus                          transcription factor;DNA-directed from RNA polymerase II promo
               regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcriptionDNA polymerase;chromatin/chr
               dorsal/ventral axis specification                                  signaling molecule
               sulfur metabolic process                                           transferase
               regulation of transcription from RNA polymerase II promoter

                                                                           kinase;protein phosphatase;kinase;protein phosphatase;calmodu
              calcium-mediated signaling;protein modification process;calcium-mediated signaling
              induction of apoptosis
 g protein 2;RSAD2;ortholog
                                                                           interleukin superfamily
              immune system process;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell s
              anion transport                                              anion channel
                                            tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                            tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis

                                              tight junction                  tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                               to stimulus
              B cell mediated immunity;natural killer cell activation;responsemembrane-bound signaling molecule;receptor;defense/immunity
                                                                              membrane trafficking regulatory protein
              neurological system process;lysosomal transport;intracellular protein transport
              proteolysis                                                     serine protease;serine protease
              purine base metabolic process;pyrimidine base metabolic process nucleotide kinase;nucleotide kinase
              cation transport;signal transduction;signal transduction        cyclic nucleotide-gated ion channel;voltage-gated potassium cha

                                                                                immunoglobulin receptor superfamily;protein phosphatase;protein
              immune system process;muscle contraction;induction of apoptosis;cell cycle;cell surface receptor linked signal transduction;ce
                                               extracellular transduction;cell-cell adhesion;ectoderm development
              signal transduction;cell-cell adhesion;signal matrix              extracellular matrix structural protein
                                               extracellular matrix             extracellular matrix structural protein
              cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component morpho
                                             extracellular matrix       extracellular matrix structural protein
             cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component morpho


                                              extracellular matrix            extracellular matrix structural protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                              extracellular matrix            extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component morphogenesis;cellular component morp
                                              extracellular matrix            extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component morphogenesis;cellular component morp
                                              extracellular matrix            extracellular matrix structural protein
             signal transduction;cell adhesion;signal transduction;cell adhesion;mesoderm development;skeletal system development
             asymmetric protein localizationextracellular matrix              extracellular matrix structural protein
             neurological system process;metabolic process                    methyltransferase
             proteolysis
             coenzyme metabolic process
                                              actin cytoskeleton              non-motor actin binding protein
             intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular componen
                                              actin cytoskeleton              non-motor actin binding protein
             intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular componen
             proteolysis                                                      metalloprotease;metalloprotease
             proteolysis                                                      metalloprotease;metalloprotease
             proteolysis                                                      metalloprotease;metalloprotease
                                              extracellular matrix            receptor;extracellular receptor linked
             immune system process;cell surface receptor linked signal transduction;cell surfacematrix protein signal transduction
             mRNA polyadenylation                                             endoribonuclease;mRNA polyadenylation factor;nuclease
                                                                              acetyltransferase;acyltransferase
             cellular amino acid metabolic process;fatty acid metabolic process
                                                                              acetyltransferase;acyltransferase
             cellular amino acid metabolic process;fatty acid metabolic process

             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

                                           actin cytoskeleton
            mesoderm development;muscle organ development                actin family cytoskeletal protein
            G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
g;calmodulin binding;calcium-dependent phospholipid binding              annexin;calmodulin
                                                                         structural protein;chaperone
            immune system process;muscle contraction;visual perception;sensory perception;protein folding;response to stress
            visual perception;sensory perception                         structural protein
            visual perception;sensory perception                         structural protein
            carbohydrate metabolic process                               dehydrogenase;reductase
            calcium-mediated signaling;calcium-mediated signaling        calcium-binding protein
            protein amino acid glycosylation                             glycosyltransferase

                                             actin development;muscle organ development
            immune system process;mesoderm cytoskeleton                     actin family cytoskeletal protein
            immune system process;proteolysis                               cysteine protease inhibitor
1;CSTP1;ortholog
            regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
                                             actin cytoskeleton             non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                             intermediate filament cytoskeleton;cell junction
                                                                            intermediate filament binding protein;cell junction protein;cell adh
            signal transduction;cell adhesion;signal transduction;cell adhesion
            pyrimidine base metabolic process                               ligase
            pyrimidine base metabolic process                               ligase
            proteolysis                                                     cysteine protease;cysteine protease
                                             actin cytoskeleton             non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
ARC;ortholog
                                              perception;sensory            transporter;apolipoprotein;membrane-bound signaling molecule;r
            immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s


             signal transduction;signal transduction                         G-protein modulator
             translation                                                     ribosomal protein
              respiratory electron transport chain;steroid metabolic process oxygenase
                                                                              hydroxylase;oxygenase
              respiratory electron transport chain;fatty acid metabolic process
                                                                              oxygenase
              respiratory electron transport chain;cholesterol metabolic process
                                                                              oxygenase
              respiratory electron transport chain;cholesterol metabolic process
                                                                              oxygenase
              respiratory electron transport chain;fatty acid metabolic process;steroid metabolic process
              metabolic process                                               methyltransferase
                                                                              chemokine
              immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
              MAPKKK cascade;MAPKKK cascade                                   signaling molecule
              complement activation;response to stimulus                      complement component
              tRNA aminoacylation for protein translation                     aminoacyl-tRNA synthetase
              oxidative phosphorylation;respiratory electron transport chain oxidoreductase
              gamete generation                                               RNA binding protein
                                              ribonucleoprotein complex        splicing, via spliceosome;protein metabolic process;ectoderm de
              spermatogenesis;neurological system process;nuclear mRNAribonucleoprotein

                                                                               homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                                                               cadherin
              signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                               microtubule                     non-receptor serine/threonine protein kinase;non-receptor serine
              neurological system process;protein amino acid phosphorylation;cellular component morphogenesis;cellular component morph
              DNA repair
              RNA catabolic process                                            hydrolase
                                               microtubule                     microtubule binding motor protein
              intracellular protein transport;vesicle-mediated transport;cellular component morphogenesis;cellular component morphogenesis
              immune system process;cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;cellular co
              cellular amino acid metabolic process                            decarboxylase
                                                                               nucleic acid binding;G-protein modulator
              G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad
                                                                               RNA helicase;translation initiation factor;helicase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;translation
                                                                               RNA helicase;helicase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
vity;nucleic acid binding                                                      RNA helicase;helicase
                                                                               RNA helicase;helicase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                               RNA helicase;helicase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                               RNA helicase;helicase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                               DNA helicase;helicase;hydrolase
              meiosis;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;meiosis
              fatty acid beta-oxidation                                        dehydrogenase;reductase

              intracellular signaling cascade;intracellular signaling cascade nucleic acid binding
                                                                                receptor;guanyl-nucleotide exchange factor
rotein binding;small GTPase regulator activity;guanyl-nucleotide exchange factor activity
                                                                                aldolase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                               intermediate filament cytoskeleton
                                                                                structural protein;intermediate filament
              cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morphogen
                                                                                kinase;kinase
              intracellular signaling cascade;lipid metabolic process;intracellular signaling cascade
                                                                                receptor;reductase
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;lipid metabolic process
              DNA metabolic process;pyrimidine base metabolic process reductase
                                                                                signaling molecule;protease;protease
              cell cycle;cell surface receptor linked signal transduction;intracellular signaling cascade;cell-cell signaling;proteolysis;cell cycle;
              metabolic process                                                 dehydrogenase;reductase
ansporter activity                                                              transporter


genome annotation processing.
                                                                        transmembrane receptor regulatory/adaptor protein
          neurological system process;cell surface receptor linked signal transduction;nerve-nerve synaptic transmission;cell surface rec
                                                                        acyltransferase
                                                                        homeobox transcription factor;DNA binding protein
          regulation of transcription from RNA polymerase II promoter;segment specification;mesoderm development;skeletal system de
                                                                        DNA strand-pairing protein;hydrolase
          immune system process;meiosis;DNA repair;DNA recombination;meiosis;response to stress
                                                                            dehydrogenase
             respiratory electron transport chain;cellular amino acid catabolic process;protein metabolic process

             regulation of transcription from RNA polymerase II promoter nucleic acid binding
             regulation of transcription from RNA polymerase II promoter nucleic acid binding
                                                                               transcription factor;nucleic acid binding
             negative regulation of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;termination of RNA poly
                                              microtubule                      hydrolase;microtubule binding motor protein
             spermatogenesis;fertilization;intracellular protein transport;vesicle-mediated transport;mitosis;cell motion;mitosis;chromosome
                                              microtubule                      hydrolase;microtubule binding motor protein
             spermatogenesis;fertilization;intracellular protein transport;vesicle-mediated transport;mitosis;cell motion;mitosis;chromosome
                                                                               chaperone
             nuclear mRNA splicing, via spliceosome                            RNA binding protein
                                              microtubule                      hydrolase;small GTPase;microtubule family cytoskeletal protein
             intracellular protein transport;endocytosis;cellular component morphogenesis;cellular component morphogenesis;cellular comp
                                                                               DNA methyltransferase;DNA binding protein
             DNA metabolic process;establishment or maintenance of chromatin architecture;establishment or maintenance of chromatin ar
             DNA metabolic process                                             DNA methyltransferase;DNA binding protein
                                                                                response
             B cell mediated immunity;DNA recombination;cellular defenseDNA-directed DNA polymerase
                                                                               guanyl-nucleotide exchange factor
             intracellular protein transport;phagocytosis;intracellular signaling cascade;cell motion;intracellular signaling cascade
                                                                               guanyl-nucleotide exchange factor
             intracellular protein transport;phagocytosis;intracellular signaling cascade;cell motion;intracellular signaling cascade
             protein amino acid glycosylation                                  phosphatase;phosphatase
             proteolysis                                                       metalloprotease;metalloprotease
                                                                               hydrolase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
             immune system process;respiratory electron transport chain oxidase
                                                                               protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                               protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                               protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                               protein phosphatase;protein phosphatase;kinase inhibitor
             JNK cascade;glycolysis;phospholipid metabolic process;protein amino acid phosphorylation;JNK cascade
                                                                               signaling molecule;enzyme receptor linked signal transduction;in
             cell surface receptor linked signal transduction;intracellular signaling cascade;cell surface modulator
                                                                               signaling molecule;enzyme receptor linked signal transduction;in
             cell surface receptor linked signal transduction;intracellular signaling cascade;cell surface modulator

             protein amino acid phosphorylation                               non-receptor tyrosine protein kinase;non-receptor serine/threonin
                                                                              transcription factor;nucleic acid cycle;signal transduction
             cell cycle;signal transduction;regulation of transcription from RNA polymerase II promoter;cell binding

                                                                                hydrolase;chaperone
               polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
                                                                                hydrolase;chaperone
               polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
                                                                                peptide hormone
               blood circulation;G-protein coupled receptor protein signaling pathway;cell-cell signaling;G-protein coupled receptor protein sign
                                                                                transcription factor
               cell surface receptor linked signal transduction;regulation of transcription from RNA polymerase II promoter;cell surface recepto
                                                                                membrane-bound signaling molecule
               transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein tyrosine
               cell motion                                                      calcium-binding protein
                                                                                KRAB box transcription factor;nucleic acid binding
               cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;ectoderm development;mesoderm developmen
                                                                                membrane traffic protein;G-protein modulator;calcium-binding pro
               neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
specific 3;EHMT2;ortholog
               translation                                                      translation initiation factor
               translation                                                      translation initiation factor
               phospholipid metabolic process                                   kinase;kinase
                                                                                hydrolase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                 ribonucleoprotein complex      ribonucleoprotein
               mRNA 3'-end processing;ectoderm development;nervous system development
                                                 ribonucleoprotein complex      ribonucleoprotein
               mRNA 3'-end processing;ectoderm development;nervous system development
                                                                                transcription factor;signaling molecule
               immune system process;intracellular signaling cascade;transcription from RNA polymerase II promoter;intracellular signaling ca
               cell motion                                                      signaling molecule
               cell motion                                                      signaling molecule
               fatty acid metabolic process                                     acyltransferase
r activity;transcription factor activity                                        transcription factor
3;EML3;ortholog
            carbohydrate metabolic process                                   deaminase
            metabolic process                                                epimerase/racemase
                                                                             nucleotide
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process phosphatase;nucleotide phosphatase;pyrophosphatas
                                                                             nucleotide
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process phosphatase;nucleotide phosphatase;pyrophosphatas
            regulation of transcription from RNA polymerase II promoter chromatin/chromatin-binding protein
                                                                             membrane traffic protein;G-protein modulator;calcium-binding pro
            neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
            DNA repair                                                       endodeoxyribonuclease;nuclease
            DNA repair                                                       endodeoxyribonuclease;nuclease
            cell cycle;DNA repair;DNA replication;cell cycle                 damaged DNA-binding protein;endodeoxyribonuclease;exodeoxy
                                                                             oxidoreductase
            respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
                                                                             oxidoreductase
            respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
            protein modification process                                     isomerase
                                                                             nuclear transduction;regulation of transcription binding
            female gamete generation;neurological system process;mitosis;signal hormone receptor;receptor;nucleic acid from RNA polyme

               respiratory electron transport chain                             oxidoreductase
                                                                                exoribonuclease;nuclease;esterase
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
               rRNA metabolic process                                           exoribonuclease;nuclease;hydrolase
               polysaccharide metabolic process;protein amino acid glycosylationglycosyltransferase
               polysaccharide metabolic process;protein amino acid glycosylationglycosyltransferase
               visual perception;sensory perception                             protein phosphatase;protein phosphatase
               visual perception;sensory perception                             protein phosphatase;protein phosphatase
               visual perception;sensory perception                             protein phosphatase;protein phosphatase
                                                                                transferase;ligase;hydrolase
               fatty acid metabolic process;tRNA aminoacylation for protein translation
                                                                                transfer/carrier protein
               lipid transport;vitamin transport;signal transduction;lipid metabolic process;signal transduction;ectoderm development
               cellular amino acid catabolic process                            hydrolase
                                                                                or maintenance of chromatin architecture;establishment
               transcription from RNA polymerase II promoter;establishment acetyltransferase;chromatin/chromatin-binding protein or maint
use it is now thought that this pseudogene is not transcribed.


             transcription from RNA polymerase II promoter                  zinc finger transcription factor


use it is now thought that this gene is a pseudogene.




                                                                            ubiquitin-protein ligase
             tRNA aminoacylation for protein translation                    aminoacyl-tRNA synthetase
                                                                            acyltransferase;methyltransferase;dehydrogenase;esterase
             cellular amino acid metabolic process;fatty acid biosynthetic process
                                            extracellular transduction;signal transduction;mesoderm development;skeletal system developm
             visual perception;sensory perception;signal matrix             signaling molecule;extracellular matrix glycoprotein;extracellular m
                                            extracellular transduction;signal transduction;mesoderm development;skeletal system developm
             visual perception;sensory perception;signal matrix             signaling molecule;extracellular matrix glycoprotein;extracellular m
              gluconeogenesis                                                 carbohydrate phosphatase;carbohydrate phosphatase

              proteolysis
              proteolysis
              proteolysis
              protein metabolic process                                       ubiquitin-protein ligase

                                                                               membrane-bound signaling molecule;cell adhesion molecule
              signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
              proteolysis                                                      ligase


              metabolic process
                                                                             immunoglobulin receptor superfamily;immunoglobulin receptor to
              B cell mediated immunity;natural killer cell activation;macrophage activation;signal transduction;signal transduction;response su
              cellular glucose homeostasis
              transcription from RNA polymerase II promoter                  zinc finger transcription factor
              mesoderm development;skeletal system development               guanyl-nucleotide exchange factor
                                                                             tyrosine protein kinase receptor;tyrosine protein kinase receptor;p
              transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto

                                                                            tyrosine protein kinase receptor;tyrosine protein cascade;negativ
            negative regulation of apoptosis;cell surface receptor linked signal transduction;MAPKKK cascade;JAK-STAT kinase receptor;p
KRD49;ortholog
            sensory perception                                              hydrolase

                                                                   isomerase;chaperone;calcium-binding protein
          immune system process;neurological system process;negative regulation of apoptosis;cell cycle;negative regulation of apoptos
43;FKS43_HUMAN;ortholog

ause it appears to represent expression of a repetitive element.
 genome annotation processing.

ause currently there is support for the transcript but not for the protein, and the transcript is a nonsense-mediated mRNA decay candidate.

ause currently there is insufficient support for the transcript and the protein is not supported by current protein homology data.

ause currently there is support for the transcript but not for the protein.

 ppressed because currently there is support for the transcript but not for the protein.
LYWCH1;ortholog
             respiratory electron transport chain;metabolic process            oxygenase
             respiratory electron transport chain;metabolic process            oxygenase
                                                                               RNA binding protein
             nucleobase, nucleoside, nucleotide and nucleic acid transport;induction of apoptosis;nucleobase, nucleoside, nucleotide and nu
             protein amino acid lipidation                                     acyltransferase
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                               transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
             metabolic process                                                 dehydrogenase
                                                                           glycosidase
              monosaccharide metabolic process;protein amino acid glycosylation
                                                                           serine protease;serine protease
              transmembrane receptor protein serine/threonine kinase signaling pathway;cell-matrix adhesion;proteolysis;transmembrane rec
              metabolic process                                            dehydrogenase;reductase
              cation transport                                             cation transporter
              transport                                                    signaling molecule;RNA binding protein
                                                                           transmembrane receptor regulatory/adaptor protein
              B cell mediated immunity;macrophage activation;transmembrane receptor protein tyrosine kinase signaling pathway;MAPKKK
ent of cytoskeleton;microtubule binding      microtubule                   non-motor microtubule binding protein
                                                                           GABA receptor;GABA receptor
              neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;nerve-n
                                                                           GABA receptor;GABA receptor
              neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;nerve-n
              immune system process;apoptosis;cell cycle;apoptosis;MAPKKK cascade;cell cycle;MAPKKK cascade;apoptosis;response to s
ns-interacting protein 1;GADD45GIP1;ortholog
              carbohydrate metabolic process                               dehydratase;epimerase/racemase
GALNT1;ortholog
              protein amino acid glycosylation                             glycosyltransferase
                                                                           glycosyltransferase
              polysaccharide metabolic process;protein amino acid glycosylation
                                                                           G-protein receptor protein
              G-protein coupled receptor protein signaling pathway;G-protein coupled coupled receptorsignaling pathway




            immune system process;proteolysis;blood coagulation              serine protease inhibitor
                                                                             zinc finger transcription factor;nuclease
            regulation of transcription from RNA polymerase II promoter;endoderm development;mesoderm development;heart developme
                                             heterotrimeric G-protein complexheterotrimeric
            response to interferon-gamma;macrophage activation;response to stimulus G-protein
                                             heterotrimeric G-protein complexheterotrimeric
            response to interferon-gamma;macrophage activation;response to stimulus G-protein
rotein 2;GDAP2;ortholog
                                                                             growth factor
            female gamete generation;mesoderm development;skeletal system development
                                                                             acyltransferase;G-protein modulator
            neurotransmitter secretion;intracellular protein transport;vesicle-mediated transport;intracellular signaling cascade;synaptic tran
            lipid metabolic process                                          ligase;esterase;phosphodiesterase
            transcription from RNA polymerase II promoter                    zinc finger transcription factor
                                                                             peptide hormone
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                             gap junction
            signal transduction;signal transduction                          gap junction
                                             gap junction
            signal transduction;signal transduction                          gap junction

                                                                         ligand-gated ion channel;ligand-gated ion channel
            neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;nerve-n
 1;GLT8D1;ortholog
 2;GLT8D2;ortholog
in 1;GMEB1;ortholog
                                          extracellular matrix           extracellular matrix glycoprotein
            phospholipid metabolic process                               dehydrogenase
                                                                         nucleic acid binding
                                                                         G-protein receptor protein
            G-protein coupled receptor protein signaling pathway;G-protein coupled coupled receptorsignaling pathway

                                                                           ionotropic glutamate receptor;ionotropic glutamate receptor
             neurological system process;cation transport;nerve-nerve synaptic transmission;nerve-nerve synaptic transmission
                                                                           ionotropic glutamate receptor;ionotropic glutamate receptor
             neurological system process;cation transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;nerve-n
                                                                           ionotropic signal transduction;nerve-nerve synaptic transmission
             neurological system process;cation transport;cell surface receptor linkedglutamate receptor;ionotropic glutamate receptor


             translation                                                    translation elongation factor;translation release factor
             transcription initiation from RNA polymerase II promoter       transcription factor
                                                                           transcription factor;nucleic acid binding
              transcription initiation from RNA polymerase II promoter;RNA elongation from RNA polymerase II promoter
                                                                           G-protein signaling pathway;G-protein coupled receptor protein s
              visual perception;sensory perception;G-protein coupled receptor protein modulator;calmodulin

                                                                             basic helix-loop-helix transcription factor;nucleic acid binding
             regulation of transcription from RNA polymerase II promoter;mesoderm development;angiogenesis;heart development
                                              extracellular matrix
             cell adhesion;cell adhesion;mesoderm development                extracellular matrix glycoprotein
             blood circulation;transport                                     transfer/carrier protein
             blood circulation;transport                                     transfer/carrier protein
 7;HCA127;ortholog
                                                                             nucleic acid binding;deacetylase
             negative regulation of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;establishment
                                                                             nucleic acid binding;deacetylase
             negative regulation of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;establishment
             translation

              protein amino acid methylation                               methyltransferase
              proteolysis                                                  ubiquitin-protein ligase
m-resident ubiquitin-like domain member 2 protein;HERPUD2;ortholog
                                                                           basic helix-loop-helix transcription factor;nucleic acid system
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous binding dev
                                                                           basic helix-loop-helix transcription factor;nucleic acid system
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous binding dev

hatase activity;nucleotide phosphatase activity                             nucleotide phosphatase;nucleotide phosphatase
                                                                            histone
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin architecture

              regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
                                               MHC protein defense
              antigen processing and presentation;cellularcomplex response major histocompatibility complex antigen
                                               MHC of peptide or polysaccharide antigen via MHC class II;cellular defense response
              antigen processing and presentation protein complex          major histocompatibility complex antigen
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;ectoderm development;gut mesoderm development;nervous syste
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development


 tein;HN1;ortholog
              regulation of transcription from RNA polymerase II promoter transcription factor;nucleic acid binding
              nuclear mRNA splicing, via spliceosome                       ribosomal protein
                                                                           signaling molecule
              neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
 BP3;ortholog
              visual perception;sensory perception                         calmodulin

            protein metabolic process
                                                                      Hsp70 family chaperone
            immune system process;protein folding;protein complex assembly;response to stress
 quence does not appear to represent a valid product.

              nuclear mRNA splicing, via spliceosome                        mRNA splicing factor

                                                                              peptide hormone
              apoptosis;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;mesoderm developme
                                               extracellular matrix           structural protein;extracellular matrix system development
              signal transduction;cell adhesion;signal transduction;cell adhesion;mesoderm development;skeletalstructural protein;cell adhes
              regulation of transcription from RNA polymerase II promoter transcription factor
                                                                              chromatin/chromatin-binding protein
              DNA repair;establishment or maintenance of chromatin architecture;establishment or maintenance of chromatin architecture
                                                                interferon superfamily
response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-mediate
                                                                interferon superfamily
response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-mediate
                                                                type cytokine receptor
natural killer cell activation;response to interferon-gamma;inductionIIof apoptosis;negative regulation of apoptosis;cytokine-med
                                                                 regulation of apoptosis;cytokine-mediated signaling pathway;ind
response to interferon-gamma;induction of apoptosis;negativeinterferon superfamily
                                                                interferon superfamily
natural killer cell activation;response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of a

                                                            defense/immunity protein
immune system process;signal transduction;signal transduction

                                   immunoglobulin
B cell mediated immunity;response to stimulus complex                immunoglobulin
                                                                     type I cytokine receptor
B cell mediated immunity;cytokine-mediated signaling pathway;JAK-STAT cascade;cell-cell signaling;JAK-STAT cascade;cytok
                                                                       of peptide or polysaccharide antigen via MHC class II;macropha
B cell mediated immunity;antigen processing and presentationinterleukin superfamily
                                                                     interleukin superfamily
immune system process;negative regulation of apoptosis;cytokine-mediated signaling pathway;JAK-STAT cascade;negative re
                                                                     type I cytokine receptor
immune system process;cytokine-mediated signaling pathway;MAPKKK cascade;JAK-STAT cascade;cell-cell signaling;JAK-ST
                                                                     type I cytokine receptor
natural killer cell activation;negative regulation of apoptosis;cytokine-mediated signaling pathway;negative regulation of apoptos
                                                                     immunoglobulin receptor superfamily;immunoglobulin receptor
natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stimulus su
cell motion                        actin cytoskeleton                non-motor actin binding protein
                                                                     growth factor
cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                      tyrosine kinase signaling pathway;cytokine-mediated signaling pa
intracellular protein transport;transmembrane receptor protein phosphatase;phosphatase
regulation of transcription from RNA polymerase II promoter


immune system process                                         immunoglobulin receptor superfamily;immunoglobulin receptor su
                                                               RNA polymerase II promoter;response
response to interferon-gamma;regulation of transcription from transcription factor;nucleic acid binding to stimulus
                                                               RNA polymerase II promoter;response
response to interferon-gamma;regulation of transcription from transcription factor;nucleic acid binding to stimulus
                                                              homeobox transcription factor;nucleic development
regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous systemacid binding
proteolysis                                                   ubiquitin-protein ligase
cell adhesion;cell adhesion                                   cell adhesion molecule
cell adhesion;cell adhesion                                   cell adhesion molecule
                                                              chaperone

                                                            receptor
                                                            receptor
                             intermediate filament cytoskeleton
                                                            structural protein;intermediate filament
cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                             actin component                non-motor actin binding protein
neurological system process;cellularcytoskeletonmorphogenesis;cellular component morphogenesis;cellular component morph
                             actin component                non-motor actin binding protein
neurological system process;cellularcytoskeletonmorphogenesis;cellular component morphogenesis;cellular component morph

                                                              voltage-gated potassium channel;voltage-gated ion channel
muscle contraction;neurological system process;cation transport;signal transduction;synaptic transmission;signal transduction;s
muscle contraction;blood circulation;cation transport         voltage-gated potassium channel;voltage-gated ion channel
cation transport                                              voltage-gated potassium channel;voltage-gated ion channel
muscle contraction;cation transport                           voltage-gated potassium channel;voltage-gated ion channel
cation transport;signal transduction;signal transduction      cyclic nucleotide-gated ion channel;voltage-gated potassium cha
                                                              G-protein signaling;calcium-mediated signaling;G-protein coupled
G-protein coupled receptor protein signaling pathway;calcium-mediated modulator;calcium-binding protein
                                                              voltage-gated
muscle contraction;neuronal action potential propagation;cation transport potassium channel;voltage-gated ion channel
cation transport                                              voltage-gated potassium channel;voltage-gated ion channel
neurological system process;cation transport                  voltage-gated potassium channel;voltage-gated ion channel
                                                              voltage-gated potassium channel;voltage-gated
muscle contraction;neurological system process;cation transport;synaptic transmission;synaptic transmission ion channel
                                                              voltage-gated potassium channel;voltage-gated ion channel
muscle contraction;sensory perception of sound;sensory perception;cation transport;synaptic transmission;synaptic transmissio
              muscle contraction;cation transport                               voltage-gated potassium channel;voltage-gated ion channel
              cation transport                                                  enzyme modulator

            intracellular protein transport;exocytosis                          receptor;membrane trafficking regulatory protein
 ;RRP1B;ortholog

mall GTPase regulator activity                                                  G-protein modulator

             carbohydrate transport;carbohydrate metabolic process       carbohydrate transporter
mall GTPase regulator activity                                           G-protein modulator
             regulation of transcription from RNA polymerase II promoter exoribonuclease;nuclease

              cation transport                                                  ligand-gated ion channel;ligand-gated ion channel




                                                                                nucleic acid binding
              general transcription from RNA polymerase II promoter             DNA binding protein

                                                                                methyltransferase




n KIAA1468;KIAA1468;ortholog
            nuclear mRNA splicing, via spliceosome                              mRNA splicing factor




              transcription from RNA polymerase II promoter

              DNA metabolic process                                        DNA methyltransferase;DNA binding protein
                                                                           nucleic acid binding;G-protein modulator
              G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad


              intracellular protein transport microtubule                         microtubule binding motor protein
                                                  microtubule                     microtubule binding motor protein
              intracellular protein transport;mitosis;mitosis;cellular component morphogenesis;cellular component morphogenesis;cellular co
                                                  microtubule                     microtubule binding motor protein
              intracellular protein transport;mitosis;meiosis;mitosis;meiosis;cellular component morphogenesis;cellular component morphoge
              intracellular protein transport microtubule                         microtubule binding motor protein
              intracellular protein transport microtubule                         microtubule binding motor protein
                                                  microtubule                     microtubule binding motor protein
              intracellular protein transport;cellular component morphogenesis;cellular component morphogenesis;cellular component morph
                                                                                  immunoglobulin receptor superfamily;immunoglobulin receptor t
              natural killer cell activation;cell surface receptor linked signal transduction;cell-cell signaling;cell surface receptor linked signalsu

                                                                                 glucosidase;glycosidase
              carbohydrate metabolic process;translation;protein modification process
                                                 microtubule
              intracellular protein transport;vesicle-mediated transport         microtubule family cytoskeletal protein
              regulation of transcription from RNA polymerase II promoter zinc finger transcription factor
                                                 actin component                 non-motor actin binding protein
              neurological system process;cellularcytoskeletonmorphogenesis;cellular component morphogenesis;cellular component morph
                                                                                 receptor;defense/immunity protein
              natural killer cell activation;signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;response to stimulus
                                                                                 guanyl-nucleotide protein signaling
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptorexchange factor pathway
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morphogen
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis

                                         intermediate filament cytoskeleton
                                                                        structural protein;intermediate filament
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis

                                                                             transcription or maintenance of chromatin architecture;establishm
             regulation of transcription from RNA polymerase II promoter;establishment factor;chromatin/chromatin-binding protein
                                                                             non-receptor serine/threonine protein
             intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling cascade kinase;non-receptor serine
                                              extracellular matrix           extracellular matrix linker protein
             signal transduction;cell-matrix adhesion;cell-cell adhesion;signal transduction;cell-matrix adhesion;cell-cell adhesion;ectoderm
ansporter activity                                                           transporter


                                                                             non-receptor serine/threonine protein kinase;non-receptor serine
             cell cycle;intracellular signaling cascade;protein amino acid phosphorylation;cell cycle;intracellular signaling cascade
                                                                             structural protein
                                                                             non-receptor tyrosine protein kinase;non-receptor tyrosine protein
             female gamete generation;immune system process;carbohydrate transport;cell cycle;intracellular signaling cascade;carbohydra
             glycolysis                                                      dehydrogenase
             regulation of transcription from RNA polymerase II promoter nucleic acid binding


                                              morphogenesis;cellular component morphogenesis;cellular component morphogenesis
               cell motion;cellular component actin cytoskeleton             actin family cytoskeletal protein
                                              intermediate filament cytoskeleton
                                                                             structural protein;intermediate filament
               cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                               promoter;cellular
               immune system process;transcription from RNA polymerase IItranscription factordefense response
                                                                             transcription cofactor
               transcription from RNA polymerase II promoter;ectoderm development;nervous system development
               asymmetric protein localizationcytoskeleton;cell junction     cytoskeletal protein;cell junction protein
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
ause it is a nonsense-mediated mRNA decay (NMD) candidate.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
y suppressed because currently there is support for the transcript but not for the protein.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.

genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
suppressed because the CDS was partial.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.

 genome annotation processing.
 genome annotation processing.
because currently there is insufficient support for the protein and the transcript and the locus is entirely composed of repetitive sequence.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
y suppressed because currently support for the transcript exists but not for the protein.
 genome annotation processing.
y suppressed because it is now thought that this gene is a pseudogene.
y suppressed because the CDS was partial.
 genome annotation processing.
                                                                              peptide hormone;serine protease;serine protease;protease inhibi
            immune system process;blood circulation;lipid transport;apoptosis;lipid metabolic process;proteolysis;mesoderm development;
                                             morphogenesis;cellular component morphogenesis;cellular component morphogenesis
            cell motion;cellular component actin cytoskeleton                 actin family cytoskeletal protein
            immune system process
                                             extracellular matrix             receptor;extracellular matrix protein
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                             adhesion;cell adhesion
            female gamete generation;cell extracellular matrix                receptor;extracellular matrix glycoprotein
                                             extracellular pathway;G-protein coupled receptor protein signaling pathway
            G-protein coupled receptor protein signalingmatrix                receptor;extracellular matrix protein

 zyme regulator activity                                                     enzyme modulator
                                           adhesion;cell adhesion
             female gamete generation;cell extracellular matrix              receptor;extracellular matrix glycoprotein
             transport;protein folding                                       apolipoprotein
             immune system process
C16A;ortholog

             signal transduction;signal transduction
                                             extracellular matrix             receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                            extracellular matrix             receptor;extracellular matrix protein
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                            extracellular pathway;G-protein coupled receptor protein signaling pathway
            G-protein coupled receptor protein signalingmatrix               receptor;extracellular matrix protein
            nuclear mRNA splicing, via spliceosome                           mRNA splicing factor
            immune system process                                            transmembrane receptor regulatory/adaptor protein
                                                                             hydrolase;defense/immunity protein
            immune system process;carbohydrate metabolic process;response to stress
LZTFL1;ortholog

                                                                        guanyl-nucleotide exchange factor
             neurological system process;induction of apoptosis;JNK cascade;induction of apoptosis;synaptic transmission;JNK cascade;ind
             gamete generation;apoptosis
                                            actin cytoskeleton          actin binding motor protein
             muscle contraction;cell motion;cellular component morphogenesis;cellular component morphogenesis;mesoderm development

 hydrolyzing N-glycosyl compounds                                             glycosidase

                                               microtubule                 non-motor microtubule binding protein
             apoptosis;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                           non-receptor
             MAPKKK cascade;protein amino acid phosphorylation;MAPKKK cascade serine/threonine protein kinase;non-receptor serine
                                                                           non-receptor
             MAPKKK cascade;protein amino acid phosphorylation;MAPKKK cascade serine/threonine protein kinase;non-receptor serine
                                                                           non-receptor serine/threonine protein kinase;non-receptor serine
             immune system process;muscle contraction;neurological system process;MAPKKK cascade;calcium-mediated signaling;synap
                                               microtubule                 non-motor microtubule binding protein
             cell cycle;cell cycle;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                               microtubule                 non-motor microtubule binding protein
             apoptosis;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             protein amino acid phosphorylation                            non-receptor serine/threonine protein kinase;non-receptor serine
             protein amino acid phosphorylation                            non-receptor serine/threonine protein kinase;non-receptor serine
             DNA repair                                                    methyltransferase;nuclease
             cell cycle;cell cycle                                         receptor


ppressed because it is now thought that this gene does encode a protein.
ause currently there is support for the transcript but not for the protein.
quence does not appear to represent a valid product.

genome annotation processing.

             transport                                                     transporter
             regulation of transcription from RNA polymerase II promoter basic helix-loop-helix transcription factor;nucleic acid binding
             meiosis;DNA repair;meiosis                                    DNA binding protein
                                                                           methyltransferase;DNA or maintenance
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment binding protein of chromatin architecture
                                                                           methyltransferase;DNA or maintenance
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment binding protein of chromatin architecture
                                                                           reductase
             proteolysis                      extracellular matrix         metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                      extracellular matrix         metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                      extracellular matrix         metalloprotease;metalloprotease;extracellular matrix protein
             proteolysis                      extracellular matrix         metalloprotease;metalloprotease;extracellular matrix protein
             meiosis;meiosis                                               structural protein
             immune system process                                         defense/immunity protein
             acyl-CoA metabolic process;acyl-CoA metabolic process         acyltransferase
                                              cell junction                nucleotide kinase;protein phosphorylation;signal transduction;syn
             neurotransmitter secretion;signal transduction;synaptic transmission;protein amino acid kinase;nucleotide kinase;protein kinase
             translation                                                   ribosomal protein

             translation                                                      ribosomal protein
ent of ribosome;nucleic acid binding                                          ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             regulation of transcription from RNA polymerase II promoter transcription cofactor;enzyme modulator
                                                                            receptor
             B cell mediated immunity;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;respon
             meiosis;DNA repair;meiosis                                     damaged DNA-binding protein
                                              actin cytoskeleton            actin family cytoskeletal protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                            reductase
             immune system process;protein modification process;response to stress
                                                                            homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;mesoderm development;skeletal system development
                                              mitochondrion;organelle       dehydrogenase;ligase;hydrolase
             purine base metabolic process;cellular amino acid biosynthetic process
                                                                            phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process
             translation                                                    translation release factor

             cholesterol metabolic process;protein amino acid phosphorylation kinase;kinase
                                                                              basic helix-loop-helix transcription cycle
             induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;cell factor;nucleic acid binding
                                             actin cytoskeleton               actin binding motor protein
             muscle contraction;mitosis;cytokinesis;cell motion;mitosis;cellular component morphogenesis;cellular component morphogenes
                                              morphogenesis;cellular component morphogenesis;mesoderm development;cellular componen
             cell motion;cellular component actin cytoskeleton                actin binding motor protein
             muscle contraction              actin cytoskeleton               actin family cytoskeletal protein;calmodulin
                                             development;muscle organ development cytoskeletal protein;calmodulin
             muscle contraction;mesoderm actin cytoskeleton                   actin family
             muscle contraction;protein amino acid phosphorylation            non-receptor serine/threonine protein kinase;non-receptor serine
                                             extracellular matrix;actin cytoskeleton
                                                                              extracellular matrix protein;actin family cytoskeletal protein;cell ad
             muscle contraction;cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular
             proteolysis                                                      protease;protease
             immune system process;induction of apoptosis
             immune system process;induction of apoptosis

BPF14;ortholog
                                                                       immunoglobulin receptor superfamily;protein phosphatase;protein
             immune system process;muscle contraction;neurological system process;induction of apoptosis;cell cycle;cell surface receptor
             nuclear mRNA splicing, via spliceosome                    mRNA splicing factor
             immune response;response to stimulus                      oxidase

                                                                           receptor
             regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

                                                                         transferase
            immune system process;signal transduction;sulfur metabolic process;polysaccharide metabolic process;protein modification pr
            respiratory electron transport chain;protein folding
omplex subunit 6;NDUFB6;ortholog
            transport                                                    ATP-binding cassette (ABC) transporter
                                                                         ubiquitin-protein ligase
            gamete generation;cell motion;ectoderm development;nervous system development
                                                                         basic helix-loop-helix transcription factor;nuclease
            regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                             actin cytoskeleton          actin family cytoskeletal protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                          stress
            immune system process;mesoderm development;response totranscription factor
                                                                          stress
            immune system process;mesoderm development;response totranscription factor
            transcription from RNA polymerase II promoter                transcription factor;nucleic acid binding
            regulation of transcription from RNA polymerase II promoter
                                             adhesion;cell adhesion
            female gamete generation;cell extracellular matrix           receptor;extracellular matrix glycoprotein

omolog;NIP7;ortholog
                                                                 metalloprotease;metalloprotease
intracellular protein transport;proteolysis;mitochondrial transport;mitochondrial transport
pyrimidine base metabolic process                                nucleotide kinase;nucleotide kinase
                                  extracellular matrix
mesoderm development;skeletal system development                 signaling molecule;extracellular matrix protein

rRNA metabolic process;translation                                ribosomal protein
ectoderm development;nervous system development                   transcription factor
proteolysis                                                       metalloprotease;metalloprotease
                                                                  nuclear promoter;signal transduction
signal transduction;regulation of transcription from RNA polymerase II hormone receptor;receptor
                                                                  immunoglobulin receptor superfamily;protein phosphatase;protein
immune system process;muscle contraction;induction of apoptosis;cell cycle;cell surface receptor linked signal transduction;ce
                                                                  transcription cofactor;aspartic protease;aspartic protease
intracellular protein transport;regulation of transcription from RNA polymerase II promoter;proteolysis

mitosis;mitosis                                                membrane trafficking regulatory protein
protein targeting;signal transduction;signal transduction      enzyme modulator
rRNA metabolic process                                         methyltransferase;nucleic acid binding
                                extracellular matrix           extracellular matrix linker protein
neurological system process;signal transduction;cell-matrix adhesion;cell-cell adhesion;signal transduction;cell-matrix adhesion
                                extracellular matrix           extracellular matrix linker protein
signal transduction;cell-matrix adhesion;signal transduction;cell-matrix adhesion;ectoderm development;nervous system develo
cellular calcium ion homeostasis                               nucleic acid binding;annexin;calmodulin
phospholipid metabolic process                                 phosphatase;phosphatase

                                                                 nucleotidyltransferase;nucleic acid binding;defense/immunity
response to interferon-gamma;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;response to stimuluspro
apoptosis;metabolic process                                      enzyme modulator
RNA elongation from RNA polymerase II promoter                   transcription cofactor
                                                                 membrane-bound signaling molecule;cell adhesion molecule
signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
regulation of transcription from RNA polymerase II promoter transcription factor
oxidative phosphorylation;respiratory electron transport chain transferase;oxidoreductase
                                                                 receptor
neurological system process;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                 receptor
neurological system process;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                 receptor
cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;ectoderm development;nervous
                                                                 hydrolase
immune system process;cellular amino acid biosynthetic process;response to toxin




cell cycle;DNA replication;cell cycle                           replication origin binding protein

lipid transport;cholesterol metabolic process                   transfer/carrier protein
proteolysis                                                     metalloprotease;metalloprotease

                                                             homeobox transcription factor;DNA binding protein
regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development
mitosis;mitosis;chromosome segregation;sex determination protease;nucleic acid binding;protease
female gamete generation;fertilization;proteolysis           serine protease;serine protease
mRNA polyadenylation
              signal transduction;signal transduction
              mitosis;mitosis                                                 nucleotidyltransferase
                                              extracellular matrix            extracellular matrix adhesion
              signal transduction;cell-matrix adhesion;proteolysis;signal transduction;cell-matrixprotein;serine protease inhibitor
              complement activation;proteolysis;response to stimulus          metalloprotease;metalloprotease;complement component
              signal transduction;signal transduction                         small GTPase


                                                                              serine/threonine protein kinase receptor;serine/threonine protein
eceptor protein kinase activity;transmembrane receptor protein serine/threonine kinase activity;transmembrane receptor protein kinase activi
                                                                              homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              cadherin
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
             ectoderm development;nervous system development
                                                perception;sensory            signaling molecule;receptor;metalloprotease;serine protease;met
             immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s
unit 15;MED15;ortholog
             mitosis;protein amino acid phosphorylation;mitosis               non-receptor serine/threonine protein kinase;non-receptor serine
             immune system process;cellular defense response
             immune system process;cellular defense response
                                                                              growth factor
             cell cycle;transmembrane receptor protein tyrosine kinase signaling pathway;calcium-mediated signaling;cell-cell signaling;cell
             intracellular signaling cascade;intracellular signaling cascade
             protein modification process;proteolysis;translation             transcription factor;metalloprotease;nucleic acid binding;metallop
             intracellular protein transport;peroxisomal transport
             glycolysis                                                       mutase
             intracellular protein transport;proteolysis                      transporter
             pentose-phosphate shunt                                          hydrolase
             immune system process;apoptosis;carbohydrate metabolic process   signaling molecule;receptor;defense/immunity protein
                                                                              cysteine protease;cysteine protease
             signal transduction;cell-cell signaling;proteolysis;signal transduction;cell-cell signaling
                                                                              RNA binding protein
                                                                              acetyltransferase;zinc finger transcription factor;chromatin/chrom
             induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;protein amino acid acetylation;cell
             proteolysis                                                      ubiquitin-protein ligase
                                                                              dehydrogenase
             carbohydrate metabolic process;cellular amino acid biosynthetic process
                                                                              hydroxylase
             fatty acid metabolic process;ectoderm development;nervous system development
ke;PHYHIPL;ortholog
             spermatogenesis;fertilization;immune system process              defense/immunity protein
                                               vesicle coat
             intracellular protein transport;receptor-mediated endocytosis vesicle coat protein

PILRB;ortholog
                                                                        RNA nucleic acid metabolic process;calcium-mediated signaling
            calcium-mediated signaling;nucleobase, nucleoside, nucleotide andbinding protein
            DNA recombination
              cation transport;endoderm development                         ion channel
                                                                            phospholipase
              signal transduction;phospholipid metabolic process;signal transduction
              phospholipid metabolic process                                phospholipase
              intracellular protein transport;endocytosis                   receptor
              complement activation;proteolysis;response to stimulus        metalloprotease;metalloprotease;complement component

             transcription from RNA polymerase II promoter                 zinc finger transcription factor
 member 3;PLEKHG3;ortholog
                                                                           guanyl-nucleotide exchange factor
             neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling
mall GTPase regulator activity;guanyl-nucleotide exchange factor activity  guanyl-nucleotide exchange factor
                                                                             process;blood coagulation
             immune system process;lipid transport;phospholipid metabolictransfer/carrier protein
                                                                           transfer/carrier to stress;defense response to bacterium
             macrophage activation;lipid transport;cholesterol metabolic process;responseprotein;antibacterial response protein
 1;PMAIP1;ortholog
             meiosis;DNA repair;meiosis                                    DNA binding protein
             fatty acid metabolic process                                  acyltransferase;phospholipase
             coenzyme metabolic process;fatty acid metabolic process       oxidase
                                                                            cycle
             cell cycle;DNA recombination;DNA repair;DNA replication;cell DNA-directed DNA polymerase;exodeoxyribonuclease;nuclease
             cell cycle;DNA replication;cell cycle                         transcription factor;DNA-directed DNA polymerase
                                              nucleus                      transcription factor;DNA-directed from RNA polymerase II promo
             regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcriptionDNA polymerase;chromatin/chr
             general transcription from RNA polymerase II promoter         nucleotidyltransferase;DNA-directed RNA polymerase
 J4, pseudogene (POLR2J4), non-coding RNA

HUMAN;ortholog
                                                                            signaling molecule;cell adhesion molecule
             visual perception;sensory perception;signal transduction;cell-matrix adhesion;signal transduction;cell-matrix adhesion;mesoder
             regulation of transcription from RNA polymerase II promoter homeobox transcription factor
                                                                             cascade;regulation of carbohydrate metabolic process;glycogen
             immune system process;mitosis;meiosis;intracellular signalingprotein phosphatase;protein phosphatase;calcium-binding protein
             protein targeting;cell adhesion;cell adhesion;ectoderm development;nervous system development
                                                                            protein phosphatase;protein phosphatase
             apoptosis;meiosis;glycogen metabolic process;mRNA processing;protein amino acid phosphorylation;meiosis
P1R11;ortholog
             apoptosis
                                                                            signaling molecule;phosphatase signaling
             neurological system process;G-protein coupled receptor protein signaling pathway;intracellular inhibitor cascade;intracellular s
             mitosis;cell motion;mitosis      microtubule                   phosphatase modulator;microtubule family cytoskeletal protein
                                                                            protein phosphatase;protein phosphatase
             intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling cascade
                                                                            protein phosphatase;protein phosphatase;calmodulin
             calcium-mediated signaling;protein modification process;calcium-mediated signaling
             protein amino acid lipidation                                  esterase




              regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
                                                                           DNA binding protein
              amino acid transport;transcription from RNA polymerase II promoter;cellular amino acid metabolic process
                                                                           phosphatase;phosphatase
              G-protein coupled receptor protein signaling pathway;phosphate metabolic process;lipid metabolic process;G-protein coupled r
                                                                           kinase modulator
              immune system process;gluconeogenesis;cholesterol metabolic process;protein amino acid phosphorylation;response to stress
                                                                           non-receptor serine/threonine
              calcium-mediated signaling;protein amino acid phosphorylation;calcium-mediated signaling protein kinase;transfer/carrier prote
                                                                           non-receptor serine/threonine protein kinase;non-receptor serine
              muscle contraction;neurological system process;mitosis;intracellular signaling cascade;protein amino acid phosphorylation;mito
              spermatogenesis

                                                                           homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development

              lipid transport;lipid metabolic process                      enzyme modulator
          protein amino acid phosphorylation                                protein phosphatase;protein phosphatase
                                                                            protein phosphatase;protein phosphatase
          cell cycle;cell surface receptor linked signal transduction;intracellular signaling cascade;protein amino acid phosphorylation;cell
                                                                            receptor;protein phosphatase;protein phosphatase
          cell cycle;transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell adhesion;protein amino acid phosphorylat
                                                                            receptor;protein phosphatase;protein phosphatase
          immune system process;signal transduction;cell-cell adhesion;protein amino acid phosphorylation;signal transduction;cell-cell a
          protein amino acid phosphorylation;cellular glucose homeostasis   receptor;protein phosphatase;protein phosphatase
                                                                            receptor;protein acid phosphorylation;cell surface
          cell surface receptor linked signal transduction;cell-cell adhesion;protein aminophosphatase;protein phosphatase receptor linke
                                                                            transcription factor;nucleic acid binding
          mitosis;regulation of transcription from RNA polymerase II promoter;DNA repair;mitosis;chromosome segregation
          general transcription from RNA polymerase II promoter             transcription factor;DNA binding protein
          tRNA metabolic process                                            lyase
                                                                            receptor;defense/immunity adhesion
          immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cellprotein
                                                                            metabolic process
          immune system process;oxygen and reactive oxygen species peroxidase
                                                                            transferase
          cellular amino acid biosynthetic process;protein modification process
          tRNA aminoacylation for protein translation                       transferase;ligase;hydrolase
                                                                            small GTPase
          intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            guanyl-nucleotide exchange factor
          neurological system process;signal transduction;synaptic transmission;signal transduction;synaptic transmission
                                                                            small GTPase
          intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            small GTPase
          intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            small GTPase
          intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            small GTPase
          intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
          intracellular protein transport                                   guanyl-nucleotide exchange factor
genome annotation processing.
                                                                            DNA helicase;helicase
          regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
          cell cycle;DNA repair;cell cycle                                  kinase activator
          B cell mediated immunity;DNA recombination;response to stimulus   endodeoxyribonuclease;nuclease;hydrolase

            proteolysis                                                     serine protease;serine protease
                                                                            receptor
            protein targeting;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
            intracellular protein transport;nuclear transport               transporter;transfer/carrier protein
            cell adhesion;cell adhesion                                     G-protein modulator
                                                                            guanyl-nucleotide exchange factor
            cell surface receptor linked signal transduction;MAPKKK cascade;MAPKKK cascade;cell surface receptor linked signal transdu
            MAPKKK cascade;MAPKKK cascade                                   guanyl-nucleotide exchange factor
                                                                            guanyl-nucleotide exchange factor
            G-protein coupled receptor protein signaling pathway;transmembrane receptor protein tyrosine kinase signaling pathway;intrace
            regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
            mRNA polyadenylation                                            nuclease
            mRNA processing                                                 RNA binding protein
                                                                            RNA binding protein
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
            mRNA processing                                                 RNA binding protein
                                                                            signaling development
            intracellular signaling cascade;intracellular signaling cascade;ectoderm molecule

            calcium-mediated signaling;calcium-mediated signaling          calmodulin
            DNA metabolic process;RNA catabolic process                    DNA binding protein
            DNA metabolic process;RNA catabolic process                    DNA binding protein
            metabolic process                                              dehydrogenase;reductase




            cell cycle;DNA replication;cell cycle                          nucleotidyltransferase;DNA-directed DNA polymerase

            regulation of transcription from RNA polymerase II promoter transcription cofactor;nuclease
4;Rgag4;ortholog
                                                                        guanyl-nucleotide exchange factor
            G-protein coupled receptor protein signaling pathway;transmembrane receptor protein tyrosine kinase signaling pathway;intrace


                                                                           G-protein receptor protein signaling pathway;dorsal/ventral axis s
              G-protein coupled receptor protein signaling pathway;G-protein coupled modulator
              transport                                                    cation transporter
              transport                                                    cation transporter
                                                                           small GTPase
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway

              intracellular protein transport;endocytosis                 membrane trafficking regulatory protein;guanyl-nucleotide exchan
              regulation of transcription from RNA polymerase II promoter zinc finger transcription factor
                                                                          non-receptor serine/threonine protein kinase;non-receptor serine
              induction of apoptosis;JNK cascade;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;protein amino acid phosphory
              transcription from RNA polymerase II promoter               zinc finger transcription factor
              protein metabolic process                                   RNA binding protein;ubiquitin-protein ligase

              spermatogenesis                                                  zinc finger transcription factor
                                                                               RNA polymerase II promoter;protein metabolic
              intracellular signaling cascade;regulation of transcription from transcription cofactor;ubiquitin-protein ligase process;intracellu

              regulation of transcription from RNA polymerase II promoter zinc finger transcription factor
              transcription from RNA polymerase II promoter                   transcription factor
              protein modification process                                    ubiquitin-protein ligase
                                                                              ubiquitin-protein ligase
              synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteolysis;signa




             purine base metabolic process                                    nucleotide kinase;nucleotide kinase
                                                                              non-receptor serine/threonine protein kinase;non-receptor serine
             cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade
                                                                              non-receptor serine/threonine protein kinase;non-receptor serine
             cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade
                                               perception;sensory             signaling molecule;receptor;metalloprotease;serine protease;met
             immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s
                                                                              membrane traffic protein
             intracellular protein transport;ectoderm development;nervous system development
                                              extracellular matrix            receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
mall GTPase regulator activity                                                G-protein modulator
                                                                              transcription cofactor;DNA helicase;helicase
             regulation of transcription from RNA polymerase II promoter;mesoderm development;embryonic development
                                                                              ligand-gated ion channel;ligand-gated ion channel
             muscle contraction;cation transport;calcium-mediated signaling;calcium-mediated signaling
 osphatase regulator activity                                                 phosphatase modulator
             intracellular protein transport;vesicle-mediated transport       small GTPase


              intracellular protein transport;exocytosis;endocytosis            transferase;transfer/carrier protein
              cell cycle;cell cycle
              neurological system process
                                                                                ion channel
              blood circulation;sensory perception of taste;cation transport;regulation of vasoconstriction
              metabolic process                                                 transfer/carrier protein;dehydrogenase;reductase
              regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
                                               extracellular transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;mesoderm dev
              visual perception;sensory perception;signal matrix                extracellular matrix glycoprotein
                                                                                transcription factor
              rRNA metabolic process;termination of RNA polymerase II transcription
                                               SNARE
              intracellular protein transport;exocytosiscomplex                 SNARE protein
                                                                                membrane-bound signaling molecule
              signal transduction;signal transduction;ectoderm development;mesoderm development;angiogenesis;nervous system developm
                                                                                membrane-bound signaling molecule
              immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein ty
                                                                          membrane-bound signaling molecule
             immune system process;cell surface receptor linked signal transduction;intracellular signaling cascade;cell surface receptor link

             immune system process;proteolysis;response to toxin             serine protease;serine protease
             proteolysis                                                     serine protease inhibitor
             proteolysis                                                     serine protease inhibitor
             proteolysis                                                     serine protease inhibitor
             proteolysis                                                     serine protease inhibitor
             proteolysis                                                     serine protease inhibitor
             proteolysis                                                     serine protease inhibitor
             cell cycle;cell cycle                                           transcription factor

                                                                               signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling

             nuclear mRNA splicing, via spliceosome                         mRNA splicing factor
             nuclear mRNA splicing, via spliceosome                         mRNA splicing factor
                                                                            non-receptor serine/threonine protein kinase;non-receptor serine
             cell cycle;MAPKKK cascade;protein amino acid phosphorylation;cell cycle;MAPKKK cascade;ectoderm development;mesoderm
                                                                             tyrosine kinase signaling pathway;cytokine-mediated signaling pa
             intracellular protein transport;transmembrane receptor protein phosphatase;phosphatase
                                                                            signaling
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process molecule
             intracellular protein transport                                transfer/carrier protein




             protein metabolic process

             proteolysis;ectoderm development;nervous system development    ubiquitin-protein ligase
                                                                            membrane-bound signaling molecule;immunoglobulin receptor su
             immune system process;cell surface receptor linked signal transduction;cell-cell adhesion;cell surface receptor linked signal tra
                                                                            membrane-bound signaling molecule;immunoglobulin receptor su
             immune system process;cell surface receptor linked signal transduction;cell-cell adhesion;cell surface receptor linked signal tra
             regulation of transcription from RNA polymerase II promoter transcription factor;chromatin/chromatin-binding protein;deacetyla
             cell adhesion;cell adhesion                                    G-protein modulator
                                                                            chromatin/chromatin-binding of chromatin architecture;establishm
             regulation of transcription from RNA polymerase II promoter;establishment or maintenance protein;deacetylase
             cation transport;anion transport                               cation transporter
             transport                                                      mitochondrial carrier protein;transfer/carrier protein
                                              mitochondrial inner membrane;organelle
                                                                            transporter
             anion transport;extracellular transport;sulfur metabolic process
                                                                            transporter
             anion transport;extracellular transport;sulfur metabolic process
             carbohydrate transport;carbohydrate metabolic process          carbohydrate transporter
             carbohydrate transport;carbohydrate metabolic process          carbohydrate transporter
                                                                            transporter
             nucleobase, nucleoside, nucleotide and nucleic acid transport;nucleobase, nucleoside, nucleotide and nucleic acid metabolic p
                                                                            transporter
             nucleobase, nucleoside, nucleotide and nucleic acid transport;nucleobase, nucleoside, nucleotide and nucleic acid metabolic p

             transport;lipid metabolic process                               transporter
sporter 8;SLC38A8;ortholog
             ion transport                                                   transporter
             cation transport                                                transporter
             ion transport                                                   transporter
unit 3;SLC43A1;ortholog
                                                                             transporter
             ion transport;cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             cation transport                                                cation transporter
             transport;carbohydrate metabolic process                        carbohydrate transporter;cation transporter
                                                                             amino acid acid metabolic process
             cation transport;extracellular transport;amino acid transport;cellular aminotransporter;cation transporter
             amino acid transport;cellular amino acid metabolic process amino acid transporter
             amino acid transport;cellular amino acid metabolic process amino acid transporter
             cation transport                                                 cation transporter
             cation transport                                                 cation transporter
                                              extracellular matrix            receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
             protein folding                                                  chaperone
                                                                              DNA helicase;helicase
             regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
                                                                              DNA helicase;helicase
             regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
                                                                              chromatin/chromatin-binding protein
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin architecture
ry subunit 3A;SMEK1;ortholog
                                                                              oxidase;nucleic process;cellular amino acid metabolic process
             respiratory electron transport chain;induction of apoptosis;porphyrin metabolic acid binding


             regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
             protein targeting;endocytosis                               membrane trafficking regulatory protein
             protein targeting;endocytosis                               membrane trafficking regulatory protein
             mesoderm development;skeletal system development            signaling molecule
                                                                          promoter
             immune system process;transcription from RNA polymerase IItranscription cofactor;zinc finger transcription factor;DNA binding

             proteolysis                                                    serine protease;serine protease


                                          microtubule                hydrolase;non-motor microtubule binding protein
             proteolysis;ectoderm development;nervous system development

                                                                            enzyme modulator
             immune system process;proteolysis;blood coagulation            serine protease inhibitor

g;protein binding;cysteine-type endopeptidase inhibitor activity               cysteine protease inhibitor;calcium-binding protein
                                                                               transcription factor;signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;MAPKKK cascade;transmembrane receptor protein tyrosine
             extracellular transport                                           receptor
             complement activation;response to stimulus                        complement component
             cell surface receptor linked signal transduction;intracellular signaling cascade;intracellular signaling cascade;cell surface recep
             protein targeting;vesicle-mediated transport;translation          membrane traffic protein;calcium-binding protein
             transcription from RNA polymerase II promoter                     transcription factor;nucleic acid binding
                                                                               protein kinase receptor
             transmembrane receptor protein tyrosine kinase signaling pathway;intracellular signaling cascade;transmembrane receptor pro
                                                                               transcription factor;nucleic acid binding
             immune response;negative regulation of apoptosis;negative regulation of apoptosis;JAK-STAT cascade;regulation of transcript


             protein amino acid phosphorylation                              non-receptor serine/threonine protein kinase;non-receptor serine
             phosphate metabolic process;protein amino acid phosphorylation  protein kinase;protein kinase
             intracellular signaling cascade;intracellular signaling cascade;ectoderm development;nervous system development
ent of cytoskeleton                          cytoskeleton                    cytoskeletal protein

                                              SNARE complex
             intracellular protein transport;vesicle-mediated transport       SNARE protein
                                              SNARE complex                   SNARE protein
             neurotransmitter secretion;intracellular protein transport;vesicle-mediated transport;synaptic transmission;synaptic transmission
                                              SNARE complex                   SNARE protein
             synaptic vesicle exocytosis;protein targeting;exocytosis;synaptic transmission;synaptic transmission
                                                                              protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                              protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                              transcription cofactor;DNA binding protein
             general transcription from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
                                                                             hydrolase
            sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process
                                                                             transcription factor;nucleic acid binding
            transcription initiation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
            transcription from RNA polymerase II promoter                    transcription factor
                                                                             methyltransferase;DNA or maintenance
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment binding protein of chromatin architecture
            carbohydrate transport;carbohydrate metabolic process            carbohydrate transporter
                                                                             cell
            signal transduction;cell adhesion;signal transduction;cell adhesionadhesion molecule
            nuclear mRNA splicing, via spliceosome                           mRNA processing factor;ribosomal protein
                                                                             membrane trafficking regulatory protein
            synaptic vesicle exocytosis;intracellular protein transport;exocytosis;synaptic transmission;synaptic transmission
                                                                             receptor
            cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
 polymerase I subunit B;TAF1B;ortholog

                                                                              transcription factor;nucleic acid binding
             regulation of transcription from RNA polymerase II promoter;ectoderm development;mesoderm development;nervous system d
             RNA elongation from RNA polymerase II promoter                   transcription factor
                                              protein II promoter;proteolysis enzyme modulator
             RNA elongation from RNA polymerasecomplex
             RNA elongation from RNA polymerase II promoter                   transcription cofactor
             RNA elongation from RNA polymerase II promoter                   transcription factor

                                                                          nuclease
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

             regulation of transcription from RNA polymerase II promoter transcription factor

             negative regulation of apoptosis
                                             actin cytoskeleton           non-motor actin binding protein
             signal transduction;cell motion;signal transduction;mesoderm development
                                                                          protein phosphatase;protein phosphatase
             immune system process;induction of apoptosis;cell cycle;signal transduction;cell adhesion;phospholipid metabolic process;prot
             meiosis;meiosis                                              nucleic acid binding
                                                                          non-receptor serine/threonine protein kinase;non-receptor serine
             gamete generation;signal transduction;cell adhesion;phosphate metabolic process;protein amino acid phosphorylation;signal tr

             transport                                                      transfer/carrier protein;serine protease;serine protease
                                                                            transcription factor;nucleic acid binding
             apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle

                                                                               growth factor
              cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
              protein modification process                                     acyltransferase
              protein modification process                                     acyltransferase
              DNA metabolic process                                            nucleic acid binding
                                                                               nuclear RNA polymerase II promoter;signal transduction
              sensory perception;signal transduction;regulation of transcription from hormone receptor;receptor
unit 13-like;MED13L;ortholog
                                                                               transcription factor;receptor;DNA polymerase processivity factor
              cell cycle;DNA replication;transcription initiation from RNA polymerase II promoter;cell cycle
                                                                               receptor
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
 in 1;THSD1;ortholog
                                                                               nucleic acid
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process binding
                                                                               homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;mesoderm development;skeletal system development;heart devel
                                               tight junction                  tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
              purine base metabolic process;pyrimidine base metabolic process  nucleotide kinase;nucleotide kinase
              vitamin metabolic process;pentose-phosphate shunt                transketolase
              vitamin metabolic process;pentose-phosphate shunt                transketolase
              regulation of transcription from RNA polymerase II promoter transcription cofactor
                                                perception;sensory             transporter;apolipoprotein;membrane-bound signaling molecule;r
              immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s
                                               extracellular matrix            receptor;extracellular matrix protein
              cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                               homeobox transcription factor;DNA binding protein
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;mesoderm developm
              proteolysis                                                     serine protease;serine protease
              proteolysis                                                     serine protease;serine protease
                                               extracellular matrix
              mesoderm development;skeletal system development                extracellular matrix structural protein
                                                                              tumor necrosis factor receptor
              induction of apoptosis;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                               plasma membrane                tumor necrosis factor receptor
              B cell mediated immunity;cytokine-mediated signaling pathway;cytokine-mediated signaling pathway;response to stimulus
                                                                              tumor necrosis factor receptor
              B cell mediated immunity;macrophage activation;induction of apoptosis;cytokine-mediated signaling pathway;JNK cascade;I-ka
                                                                              receptor
              immune system process;induction of apoptosis;cell surface receptor linked signal transduction;I-kappaB kinase/NF-kappaB cas
                                               development;muscle organ development actin binding protein
              muscle contraction;mesoderm actin cytoskeleton                  non-motor
              protein targeting;nuclear transport                             transporter;transfer/carrier protein
              cell cycle;transmembrane receptor protein serine/threonine kinase signaling pathway;JNK cascade;cell cycle;transmembrane r
                                               cytoskeleton
              intracellular protein transport;endocytosis                     signaling molecule;cytoskeletal protein

            intracellular protein transport;endocytosis                      transporter
                                                                             mitochondrial carrier protein;transfer/carrier protein
            intracellular protein transport mitochondrial inner membrane;organelle
                                                                             DNA topoisomerase
            cell cycle;DNA replication;general transcription from RNA polymerase II promoter;cell cycle
            apoptosis;cell cycle;cell cycle                                  enzyme modulator
            apoptosis;carbohydrate metabolic process                         dehydrogenase;reductase
P53INP1;ortholog
                                                                             transcription factor
            induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;DNA repair;cell cycle


                                                                                kinase;kinase
                                                                                tyrosine protein kinase receptor;tyrosine protein kinase receptor;p
             intracellular protein transport;nuclear transport;transmembrane receptor protein tyrosine kinase signaling pathway;protein amin
             immune system process            microtubule                       non-motor microtubule binding protein
             protein targeting;translation
e protein;TRAPPC2L;ortholog
                                                                                ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteolysis;signa
                                                                                ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;glycogen metabo
                                                                                ubiquitin-protein ligase
             synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteolysis;signa
                                              cytoskeleton                      signaling molecule;cytoskeletal protein
             intracellular protein transport;endocytosis;cell cycle;cell cycle;cellular component morphogenesis;cellular component morphoge
             tRNA metabolic process                                             RNA methyltransferase;RNA binding protein
                                                                                ion channel
             visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
                                                                                ion channel
             visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
                                                                                zinc finger transcription factor;nuclease
             regulation of transcription from RNA polymerase II promoter;endoderm development;mesoderm development;heart developme
             spermatogenesis;negative regulation of apoptosis                   chaperone
                                                                              membrane-bound signaling molecule;cell adhesion molecule
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion
                                                                              membrane-bound signaling molecule;cell adhesion molecule
             signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion

                                                                               transferase;transfer/carrier protein
             immune system process;anion transport;sulfur metabolic process;response to toxin
             apoptosis
             proteolysis                                                       protease;protease
                                                                               isomerase;chaperone
             immune system process;neurological system process;negative regulation of apoptosis;cell cycle;negative regulation of apoptos
                                              extracellular matrix;actin cytoskeleton
                                                                               extracellular matrix protein;actin family cytoskeletal protein;cell ad
             muscle contraction;cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular
             protein metabolic process        microtubule                      ligase;microtubule family cytoskeletal protein
                                              tubulin complex;tubulin complex  tubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;cellular c
                                              tubulin complex;tubulin complex  tubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;cellular c
                                              tubulin complex;tubulin complex  tubulin
             intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;cellular c
             visual perception;sensory perception;ectoderm development;nervous system development
             protein modification process                                      glycosyltransferase
             regulation of transcription from RNA polymerase II promoter basic helix-loop-helix transcription factor;nucleic acid binding
             DNA metabolic process;pyrimidine base metabolic process methyltransferase

                                                                         transfer/carrier protein;ligase
             intracellular signaling cascade;coenzyme metabolic process;protein modification process;proteolysis;intracellular signaling casc
                                                                         transfer/carrier protein;ligase
             intracellular signaling cascade;coenzyme metabolic process;protein modification process;proteolysis;intracellular signaling casc
             protein modification process                                ligase
             protein modification process                                ligase
             proteolysis                                                 ubiquitin-protein ligase
             proteolysis
             mitosis;mitosis                                             membrane trafficking regulatory protein
             polysaccharide metabolic process;steroid metabolic process glycosyltransferase

            polysaccharide metabolic process;steroid metabolic process glycosyltransferase
                                                                            zinc finger transcription factor
            nucleobase, nucleoside, nucleotide and nucleic acid transport;cell cycle;nucleobase, nucleoside, nucleotide and nucleic acid m
MC1;ortholog
                                                                            decarboxylase
                                                                            receptor
            apoptosis;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;ectoderm developmen
            spermatogenesis;mitosis;mitosis                                 DNA glycosylase;kinase activator

             pyrimidine base metabolic process                              phosphorylase
                                                                            glycosyltransferase;nucleotide kinase;nucleotide kinase
             carbohydrate metabolic process;pyrimidine base metabolic process
             oxidative phosphorylation;respiratory electron transport chain reductase
                                            mitochondrion;organelle
             oxidative phosphorylation;respiratory electron transport chain reductase
             oxidative phosphorylation;respiratory electron transport chain reductase


             proteolysis                                                       cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
             gamete generation;proteolysis                                     cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
             gamete generation;proteolysis                                     cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
             proteolysis                                                       cysteine protease;cysteine protease
              proteolysis                                                      cysteine protease;cysteine protease
              proteolysis                                                      cysteine protease;cysteine protease
              proteolysis                                                      cysteine protease;cysteine protease
              RNA catabolic process;proteolysis                                cysteine protease;exoribonuclease;nuclease;esterase;cysteine p

            transcription initiation from RNA polymerase II promoter             transcription factor
            proteolysis                                                          ligase
                                               actin cytoskeleton                non-motor actin binding protein
            cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                               intermediate filament cytoskeletonstructural protein;intermediate filament
            cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morphogen
                                                                                 hydrolase
            signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
                                                                                 hydrolase
            signal transduction;cell-cell adhesion;vitamin metabolic process;cell motion;signal transduction;cell-cell adhesion
            lysosomal transport;intracellular protein transport
            intracellular protein transport vesicle coat                         vesicle coat protein
            intracellular protein transport                                      membrane traffic protein
            intracellular protein transport                                      membrane traffic protein
                                                                                 immunoglobulin receptor superfamily;immunoglobulin receptor
            natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stimulus su
                                                                                 receptor;defense/immunity adhesion
            immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cellprotein
                                               extracellular matrix                perception;signal transduction;cell-cell adhesion;signal transduc
            immune system process;sensory perception of sound;sensoryextracellular matrix protein;cell adhesion molecule
                                               extracellular matrix
            immune system process;cell adhesion;cell adhesion;blood coagulation  extracellular matrix glycoprotein
ed-coil;WAC;ortholog
            meiosis;meiosis
            transcription from RNA polymerase II promoter
                                                                                 signaling molecule
            signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                                 signaling molecule
            signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                                 signaling molecule
            G-protein coupled receptor protein signaling pathway;cell-cell signaling;G-protein coupled receptor protein signaling pathway;ce


              DNA repair                                                       damaged DNA-binding protein

            regulation of transcription from RNA polymerase II promoter        transcription cofactor
            tRNA aminoacylation for protein translation                        nucleic acid binding;aminoacyl-tRNA synthetase
            transcription from RNA polymerase II promoter                      transcription factor;chromatin/chromatin-binding protein
            intracellular protein transport;vesicle-mediated transport
RDC;ortholog
            transcription initiation from RNA polymerase II promoter           transcription factor
            transcription from RNA polymerase II promoter                      zinc finger transcription factor
                                                                               nucleic acid binding
                                                                               nucleic acid binding


               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
               transcription from RNA polymerase II promoter                    zinc finger transcription factor
                                                endoplasmic reticulum;organelle  surface receptor linked signal transduction
               cell surface receptor linked signal transduction;proteolysis;cellmetalloprotease;metalloprotease
               regulation of transcription from RNA polymerase II promoter transcription cofactor
r activity;transcription factor activity                                        zinc finger transcription factor

               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
r activity;transcription factor activity                                   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
                                                                            nucleic acid binding;G-protein modulator
               G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               mitosis;mitosis;chromosome segregation
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;nuclease
                                                                            KRAB promoter
               spermatogenesis;regulation of transcription from RNA polymerase II box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
r activity;transcription factor activity                                    KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
                                                                            zinc finger transcription factor
               transcription from RNA polymerase II promoter;cell motion;segment specification;dorsal/ventral axis specification
               ectoderm development;nervous system development
r activity;transcription factor activity                                    KRAB box transcription factor
r activity;transcription factor activity                                    KRAB box transcription factor
                                                                            transcription factor;nuclease
               nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;DNA binding protein
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
r activity;transcription factor activity                                    KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
r activity;transcription factor activity                                    zinc finger transcription factor
             Pathway
ubule binding protein


ette (ABC) transporter
ette (ABC) transporter


erine protease
erine protease

             Axon guidance mediated by netrin->Actin binding LIM protein 1;;




ase;protein phosphatase




             Alzheimer disease-presenilin pathway->actin;;Nicotinic acetylcholine receptor signaling pathway->Actin;;Cytoskeletal regulation
             Alzheimer disease-presenilin pathway->actin;;Nicotinic acetylcholine receptor signaling pathway->Actin;;Cytoskeletal regulation

              Integrin signalling pathway->alpha actinin;;
              Alzheimer disease-presenilin pathway->actin;;Cadherin signaling pathway->Filamentous F-actin;;Huntington disease->Actin;;;;
              Huntington disease->Actin;;
              TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;
metalloprotease
              Adenine and hypoxanthine salvage pathway->Adenosine deaminase;;Adenine and hypoxanthine salvage pathway->Deoxyaden
metalloprotease
metalloprotease
metalloprotease
              Ornithine degradation->Ornithine decarboxylase;;
inding protein




             FAS signaling pathway->Poly(ADP-ribose) polymerase;;

eceptor regulatory/adaptor protein;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;immunoglobulin superfamily ce
 e;glycosidase




             De novo purine biosynthesis->Adenylate kinase;;
             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde dehydrogen
             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde dehydrogen
             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;
             Fructose galactose metabolism->Fructose bisphosphate aldolase;;Glycolysis->Aldolase;;;




ription factor;DNA binding protein
               N-acetylglucosamine metabolism->N-acetylglucosamine-6-phosphate deacetylase;;
               Purine metabolism->5'-AMP Deaminase;;




metalloprotease

             Angiogenesis->Adenomatous Polyposis of the Colon;;Wnt signaling pathway->Adenomatous Polyposis Coli;;;
erine protease
clease;exodeoxyribonuclease;nuclease




             Huntington disease->ADP-ribosylation factor;;Integrin signalling pathway->ADP ribosylation factor 1;;Integrin signalling pathway
             Huntington disease->Arfaptin-2;;
             Integrin signalling pathway->Rho;;
             PDGF signaling pathway->GTPase-activating protein Rho;;Cytoskeletal regulation by Rho GTPase->Rho-GTPase-activating pr

             PDGF signaling pathway->GTPase-activating protein Rho;;
e;G-protein modulator
e;G-protein modulator

             Integrin signalling pathway->Arp2/3;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin related protei
             Integrin signalling pathway->Arp2/3;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin related protei
             Integrin signalling pathway->Arp2/3;;Huntington disease->Actin-related protein 2 and 3 complex;;Inflammation mediated by che




 eacetylase;metalloprotease
              Ubiquitin proteasome pathway->26S proteasome;;
              Ubiquitin proteasome pathway->26S proteasome;;
              Apoptosis signaling pathway->Activating transcription factor;;

              p53 pathway feedback loops 2->ATM;;p53 pathway->Ataxia telangiectasia mutated (ATM) and Rad3-related (ATR);;;

;ion channel;hydrolase


 channel;hydrolase
 channel;hydrolase

;ion channel;hydrolase


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

              Angiogenesis->Axis inhibitor 1;;Wnt signaling pathway->Axin;;Wnt signaling pathway->Wnt Target Genes;;;;

r;nucleic acid binding

               Apoptosis signaling pathway->Bcl-2 antogonist/killer;;
ription factor;DNA binding protein
ription factor;DNA binding protein
               p53 pathway->BCL2-associated X protein;;Apoptosis signaling pathway->Bcl-2 associated x protein;;Huntington disease->Bcl-2

x glycoprotein
             Nicotinic acetylcholine receptor signaling pathway->acetylcholinesterase;;Muscarinic acetylcholine receptor 2 and 4 signaling pa




ular matrix protein


              Apoptosis signaling pathway->Bik-like killer protein;;Apoptosis signaling pathway->Bcl-2 interacting killer;;;
king regulatory protein
king regulatory protein




              TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;


              Apoptosis signaling pathway->Bcl-2 related ovarian killer;;

erine protease
eceptor regulatory/adaptor protein




ne/threonine protein kinase;non-receptor serine/threonine protein kinase

n factor;nuclease




             EGF receptor signaling pathway->phosphatidylinositol 3-kinase;;Insulin/IGF pathway-protein kinase B signaling cascade->Phos




erase;RNA binding protein
erine protease;complement component
erine protease;complement component
binding protein




ase;protein phosphatase
             Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Calcium ion channel;;Metabotropic glut
             5HT2 type receptor mediated signaling pathway->Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->Ca2+ channel;
cium channel;voltage-gated ion channel
cium channel;voltage-gated ion channel
cium channel;voltage-gated ion channel

               Ionotropic glutamate receptor pathway->stargazin;;
               Ionotropic glutamate receptor pathway->calcium/calmodulin-dependent protein kinase II;;Inflammation mediated by chemokine
 antibacterial response protein
inding protein
sis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis


acellular signaling cascade;synaptic transmission;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic tran
;cysteine protease


atin-binding protein




              Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
              Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;


              p53 pathway feedback loops 2->CYCLIN G;;p53 pathway->Cyclin G;;p53 pathway feedback loops 2->cyclin G;;;;


ctor;kinase activator
eceptor superfamily;immunoglobulin receptor superfamily;major histocompatibility complex antigen


king regulatory protein
               B cell activation->Ig-alpha;;
  signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily
 oskeletal protein
ase;protein phosphatase
              p53 pathway->Cell division cycle 25C;;


              Integrin signalling pathway->Cell division cycle 42;;Huntington disease->Rac;;Axon guidance mediated by Slit/Robo->Cell divisi
binding protein


             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
             Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase
ne/threonine protein kinase;non-receptor serine/threonine protein kinase

 r;nucleic acid binding

ng;G-protein modulator


erine protease;complement component
             Cytoskeletal regulation by Rho GTPase->Cofilin;;


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

 r;DNA-directed DNA polymerase;chromatin/chromatin-binding protein




osphatase;kinase;protein phosphatase;calmodulin




  signaling molecule;receptor;defense/immunity protein
king regulatory protein
erine protease
              De novo purine biosynthesis->Adenylate kinase;;De novo pyrmidine ribonucleotides biosythesis->Uridylate kinase;;Salvage pyr
              Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;

eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cell adhesio
             Integrin signalling pathway->Collagen;;
             Integrin signalling pathway->Collagen;;
             Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;Inflammation mediated by chemokine and cytokine signaling pathway->ExtraCellular ma
               Integrin signalling pathway->Collagen;;Inflammation mediated by chemokine and cytokine signaling pathway->ExtraCellular ma
               Integrin signalling pathway->Collagen;;
 x structural protein
               Adrenaline and noradrenaline biosynthesis->Catechol-O-Methyl Transferase;;


inding protein
inding protein
metalloprotease
              Plasminogen activating cascade->thrombin activatable fibrinolysis inhibitor;;
metalloprotease
ular matrix protein
 ;mRNA polyadenylation factor;nuclease
              Muscarinic acetylcholine receptor 2 and 4 signaling pathway->choline acetyltransferase;;
 acyltransferase




keletal protein
               Angiogenesis->Crk oncogene;;Integrin signalling pathway->Crk;;;

              VEGF signaling pathway->Heat-Shock Protein 27;;Angiogenesis->Heat-Shock Protein 27;;;




keletal protein




              Alzheimer disease-presenilin pathway->alpha-catenin;;Cadherin signaling pathway->Alpha-catenin;;Wnt signaling pathway->alp
              Cadherin signaling pathway->Delta-catenin;;
              De novo pyrmidine ribonucleotides biosythesis->CTP synthase;;
              De novo pyrmidine ribonucleotides biosythesis->CTP synthase;;
;cysteine protease
inding protein

oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;extracellul


              Huntington disease->P53 tumor suppressor phosphoprotein;;
             Vitamin D metabolism and pathway->Vitamin D 1-alpha-hydroxylase;;Vitamin D metabolism and pathway->Vitamin D 25-Hydro
             Vitamin D metabolism and pathway->Vitamin D 1-alpha-hydroxylase;;Vitamin D metabolism and pathway->Vitamin D 25-Hydro
             Nicotine degradation->cytochrome P450 subfamily IIA polypeptide 6;;

             Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;




ription factor;DNA binding protein
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase;non-motor microtubule binding protein


ng motor protein
 ;cellular component morphogenesis;cellular component morphogenesis;response to stress
                 Adrenaline and noradrenaline biosynthesis->Aromatic L-amino acid decarboxylase;;Dopamine receptor mediated signaling path
ng;G-protein modulator
nslation initiation factor;helicase




case;hydrolase




ucleotide exchange factor

ntermediate filament


             Formyltetrahydroformate biosynthesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;Folate biosynth
e;protease;protease




             Huntington disease->Postsynaptic density 95;;

ription factor;DNA binding protein
 g protein;hydrolase
 r;nucleic acid binding
               Huntington disease->Dynein complex;;
               Huntington disease->Dynein complex;;


TPase;microtubule family cytoskeletal protein
erase;DNA binding protein
erase;DNA binding protein
A polymerase
 exchange factor
 exchange factor

metalloprotease
             Axon guidance mediated by semaphorins->Collapsin response mediator protein;;Axon guidance mediated by semaphorins->CR

             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
             Wnt signaling pathway->Dishevelled;;Alzheimer disease-presenilin pathway->Dishevelled;;Angiogenesis->Dishelvelled;;;;
             Wnt signaling pathway->Dishevelled;;Alzheimer disease-presenilin pathway->Dishevelled;;Angiogenesis->Dishelvelled;;;;

sine protein kinase;non-receptor serine/threonine protein kinase;non-receptor serine/threonine protein kinase;non-receptor tyrosine protein k
 r;nucleic acid binding




             Wnt signaling pathway->NFAT Target Genes;;Endothelin signaling pathway->Big endothelin 1, 2, 3, and 4;;Endothelin signaling

             Angiogenesis->Ephrin;;

iption factor;nucleic acid binding
protein;G-protein modulator;calcium-binding protein




             PDGF signaling pathway->Ets;;
             Integrin signalling pathway->ELMO;;
hatase;nucleotide phosphatase;pyrophosphatase
hatase;nucleotide phosphatase;pyrophosphatase
atin-binding protein
 protein;G-protein modulator;calcium-binding protein
clease;nuclease
clease;nuclease
nding protein;endodeoxyribonuclease;exodeoxyribonuclease;nuclease;hydrolase




receptor;receptor;nucleic acid binding


nuclease;esterase
nuclease;hydrolase


ase;protein phosphatase
ase;protein phosphatase
ase;protein phosphatase
              Anandamide_degradation->Fatty acid amide hydrolase;;


chromatin/chromatin-binding protein




ethyltransferase;dehydrogenase;esterase
e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin;calmodulin
e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin
sphatase;carbohydrate phosphatase




 signaling molecule;cell adhesion molecule




eceptor superfamily;immunoglobulin receptor superfamily


exchange factor
           FGF signaling pathway->FGFR1-4;;Angiogenesis->Fibroblast Growth Factor Receptor-1;;;

nase receptor;tyrosine protein kinase receptor;protein kinase




one;calcium-binding protein




nonsense-mediated mRNA decay candidate.

y current protein homology data.




             Nicotine degradation->Flavin-containing monooxygenase;;
             Nicotine degradation->Flavin-containing monooxygenase;;


             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa


             Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor mediated
             Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor mediated

             Endothelin signaling pathway->Furin;;Alzheimer disease-amyloid secretase pathway->Furin;;Alzheimer disease-presenilin path


e;RNA binding protein
             EGF receptor signaling pathway->GRB2-associated binding protein;;
ubule binding protein
ABA receptor
ABA receptor
             p53 pathway->Growth arrest and DNA-damage-inducible, alpha;;p53 pathway->Growth arrest and DNA-damage-inducible, alph

erase/racemase




iption factor;nuclease




            TGF-beta signaling pathway->Transforming growth factor beta;;
-protein modulator
hosphodiesterase




hannel;ligand-gated ion channel




             Blood coagulation->Glycoprotein 1bbeta;;Blood coagulation->Glycoprotein IX;;;




             Metabotropic glutamate receptor group III pathway->AMPA/Kainate Receptor;;Ionotropic glutamate receptor pathway->Glutama
             Ionotropic glutamate receptor pathway->Kainate Receptor;;Huntington disease->Kainate receptor;;Metabotropic glutamate rece
             Metabotropic glutamate receptor group I pathway->N-methyl-D-aspartate Receptor;;Huntington disease->N-methyl-d-aspartate


tion factor;translation release factor
               General transcription regulation->TFIIA;;Transcription regulation by bZIP transcription factor->TFIIA;;;
             General transcription regulation->General Transcription factor IIF, polypeptide 1, 74-KD;;Transcription regulation by bZIP transc
tor;calmodulin

elix transcription factor;nucleic acid binding
x glycoprotein




ng;deacetylase
ng;deacetylase




              Notch signaling pathway->Enhancer of Split complex genes;;
              Notch signaling pathway->Enhancer of Split complex genes;;

hatase;nucleotide phosphatase




 tibility complex antigen
 tibility complex antigen
ription factor;DNA binding protein
ription factor;DNA binding protein
                p53 pathway->High mobility group protein 1;;
                p53 pathway->High mobility group protein 1;;

r;nucleic acid binding


ription factor;DNA binding protein
ription factor;DNA binding protein
ription factor;DNA binding protein
ription factor;DNA binding protein




              Parkinson disease->Heat shock protein 70;;Apoptosis signaling pathway->Heat shock protein 70;;;




extracellular matrix structural protein;cell adhesion molecule

atin-binding protein
             Inflammation mediated by chemokine and cytokine signaling pathway->Cytokine receptor;;
             Toll receptor signaling pathway->Gene trancription;;
             Interferon-gamma signaling pathway->Interferongamma;;Inflammation mediated by chemokine and cytokine signaling pathway

             p53 pathway by glucose deprivation->alpha4;;

             B cell activation->mIgM;;
             Interleukin signaling pathway->Receptor subunit alpha;;

             Interleukin signaling pathway->Interleukin;;
             Interleukin signaling pathway->Receptor subunit alpha;;

eceptor superfamily;immunoglobulin receptor superfamily
inding protein
              TGF-beta signaling pathway->Transforming growth factor beta;;
              Inflammation mediated by chemokine and cytokine signaling pathway->SH2 domain-containing inositol 5-phosphatase;;PI3 kin




eceptor superfamily;immunoglobulin receptor superfamily
 r;nucleic acid binding
               Toll receptor signaling pathway->Interferon (INF) regulatory factor 3;;
ription factor;nucleic acid binding
               Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;
               Integrin signalling pathway->Integrin alpha;;Integrin signalling pathway->Collagen;;;
               Integrin signalling pathway->Integrin alpha;;Inflammation mediated by chemokine and cytokine signaling pathway->Integrin;;;




 ntermediate filament
inding protein
inding protein

assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
gated ion channel;voltage-gated potassium channel;voltage-gated ion channel;cyclic nucleotide-gated ion channel
tor;calcium-binding protein
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
              Muscarinic acetylcholine receptor 1 and 3 signaling pathway->KCNQ K(+) channel;;
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel


ne trafficking regulatory protein




hannel;ligand-gated ion channel




erase;DNA binding protein
ng;G-protein modulator


ng motor protein
ng motor protein
ng motor protein
ng motor protein
ng motor protein
ng motor protein
eceptor superfamily;immunoglobulin receptor superfamily


              Alzheimer disease-amyloid secretase pathway->kinesin;;

inding protein
immunity protein
 exchange factor
ntermediate filament
ntermediate filament
ntermediate filament
ntermediate filament
ntermediate filament
ntermediate filament

ntermediate filament

r;chromatin/chromatin-binding protein
             Oxidative stress response->elongation factor 2 kinase;;p38 MAPK pathway->elongation factor-2 kinase;;;
             Integrin signalling pathway->Laminin;;




ne/threonine protein kinase;non-receptor serine/threonine protein kinase

             Integrin signalling pathway->Src;;Parkinson disease->Rous sarcoma protein tyrosine kinase;;T cell activation->Lck;;;;

             Cadherin signaling pathway->Transcription factor 4/Lymphoid enhancer-binding factor;;Alzheimer disease-presenilin pathway->


keletal protein
               FAS signaling pathway->Nuclear Lamin;;


             Notch signaling pathway->LNXp80;;
is entirely composed of repetitive sequence.




              Plasminogen activating cascade->Plasminogen;;Plasminogen activating cascade->Plasmin;;;
              Angiogenesis->Paxillin;;VEGF signaling pathway->Paxillin;;;

ular matrix protein
ular matrix glycoprotein
ular matrix protein


              Alzheimer disease-presenilin pathway->LRP C-terminal fragment;;Alzheimer disease-presenilin pathway->Low-density lipoprote




ular matrix protein
ular matrix protein
ular matrix protein

             Toll receptor signaling pathway->MD-2;;
e/immunity protein


              Apoptosis signaling pathway->Mitogen activated protein kinase activating death domain;;

              Nicotinic acetylcholine receptor signaling pathway->Myosin;;




ubule binding protein
             Alzheimer disease-amyloid secretase pathway->Mitogen activated protein kinase;;p38 MAPK pathway->p38-delta mitogen-activ
             Alzheimer disease-amyloid secretase pathway->Mitogen activated protein kinase;;EGF receptor signaling pathway->p38 MAP k
             PDGF signaling pathway->MAPKAPK2;;Angiogenesis->Mitogen-Activated Protein Kinase-Activating Protein Kinase-2 and 3;;In
ubule binding protein
ubule binding protein
ne/threonine protein kinase;non-receptor serine/threonine protein kinase
ne/threonine protein kinase;non-receptor serine/threonine protein kinase




elix transcription factor;nucleic acid binding

;DNA binding protein
;DNA binding protein

              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
              Plasminogen activating cascade->Matrix metalloprotease 1;;Alzheimer disease-presenilin pathway->Matrix metalloprotease;;Pl




              Inflammation mediated by chemokine and cytokine signaling pathway->Calcium/calModulin-dependent Kinase II;;Parkinson dis
ctor;enzyme modulator

nding protein
keletal protein

ription factor;DNA binding protein
               Formyltetrahydroformate biosynthesis->Methylenetetrahydrofolate dehydrogenase;;




               Cholesterol biosynthesis->Mevalonate kinase;;
               Wnt signaling pathway->Wnt Target Genes;;Oxidative stress response->v-myc myelocytomatosis viral oncogene homolog;;p53
               Inflammation mediated by chemokine and cytokine signaling pathway->Myosin;;Wnt signaling pathway->NFAT Target Genes;;N
               Inflammation mediated by chemokine and cytokine signaling pathway->Myosin;;Nicotinic acetylcholine receptor signaling pathw
keletal protein;calmodulin
keletal protein;calmodulin
               Cytoskeletal regulation by Rho GTPase->Myosin light chain kinase;;Inflammation mediated by chemokine and cytokine signalin
 x protein;actin family cytoskeletal protein;cell adhesion molecule




eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cell adhesio




 ette (ABC) transporter
               Notch signaling pathway->Neuralized;;
elix transcription factor;nuclease
keletal protein


r;nucleic acid binding
               Toll receptor signaling pathway->IkappaB;;Inflammation mediated by chemokine and cytokine signaling pathway->Nuclear facto
ular matrix glycoprotein
metalloprotease
              De novo purine biosynthesis->GDP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dTDP kinase;;De novo purin
e;extracellular matrix protein




metalloprotease
receptor;receptor
eceptor superfamily;protein phosphatase;protein phosphatase;immunoglobulin receptor superfamily;immunoglobulin superfamily cell adhesio
ctor;aspartic protease;aspartic protease

king regulatory protein

 ;nucleic acid binding
               Axon guidance mediated by netrin->Netrin;;Axon guidance mediated by Slit/Robo->Netrin;;;
               Axon guidance mediated by netrin->Netrin;;Integrin signalling pathway->Laminin;;Axon guidance mediated by Slit/Robo->Netrin
ng;annexin;calmodulin


rase;nucleic acid binding;defense/immunity protein


 signaling molecule;cell adhesion molecule




binding protein


metalloprotease

ription factor;DNA binding protein
acid binding;protease
erine protease
 x protein;serine protease inhibitor
metalloprotease;complement component




 rotein kinase receptor;serine/threonine protein kinase receptor;protein kinase
ription factor;DNA binding protein
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;

e;receptor;metalloprotease;serine protease;metalloprotease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion mo

ne/threonine protein kinase;non-receptor serine/threonine protein kinase


             PDGF signaling pathway->PDGF;;Angiogenesis->Platelet-Derived Growth Factor;;;

r;metalloprotease;nucleic acid binding;metalloprotease

             Glycolysis->Phosphoglyceromutase;;


e;receptor;defense/immunity protein
;cysteine protease

zinc finger transcription factor;chromatin/chromatin-binding protein

             Serine glycine biosynthesis->Phosphoglycerate dehydrogenase;;
metalloprotease;complement component




 exchange factor
 exchange factor

otein;antibacterial response protein


hospholipase
            Pyridoxal phosphate salvage pathway->Pyridoxine-5-phosphate oxidase;;Vitamin B6 metabolism->Pyridoxamine phosphate ox
            DNA replication->Pol alpha;;
r;DNA-directed DNA polymerase
r;DNA-directed DNA polymerase;chromatin/chromatin-binding protein
            General transcription by RNA polymerase I->RNA Polymerase I Complex;;




e;cell adhesion molecule

ase;protein phosphatase;calcium-binding protein
stem development
              Dopamine receptor mediated signaling pathway->Protein Phosphatase-1;;


e;phosphatase inhibitor
 ulator;microtubule family cytoskeletal protein
              FGF signaling pathway->protein phosphatase 2A;;EGF receptor signaling pathway->protein phosphatase 2A;;Wnt signaling pat
              Wnt signaling pathway->Calcineurin;;




               p53 pathway by glucose deprivation->AMP-activated protein kinase;;
               Wnt signaling pathway->Protein Kinase C;;Thyrotropin-releasing hormone receptor signaling pathway->PKC;;Alzheimer diseas
               Endothelin signaling pathway->protein kinase, cGMP-dependent;;


ription factor;DNA binding protein
ase;protein phosphatase
ase;protein phosphatase
 hosphatase;protein phosphatase
               JAK/STAT signaling pathway->protein-tyrosine phosphatase;;T cell activation->CD45;;B cell activation->CD45;;;;
 hosphatase;protein phosphatase
 hosphatase;protein phosphatase
 r;nucleic acid binding
 r;DNA binding protein

immunity protein




 exchange factor




 exchange factor




clease;nuclease;hydrolase

erine protease

er/carrier protein
               Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein 1;;
               Integrin signalling pathway->CRK SH3 domain-binding guanine nucleotide-releasing factor;;
 exchange factor
               Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Calcium and diacylglycerol-regulated g




rase;DNA-directed DNA polymerase

ctor;nuclease
 exchange factor


              Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->Regulator of G-protein signaling;;Hetero




king regulatory protein;guanyl-nucleotide exchange factor

              Apoptosis signaling pathway->Receptor interacting protein;;

ein;ubiquitin-protein ligase


ctor;ubiquitin-protein ligase




;nucleotide kinase
              Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->90 kDa ribosomal protein S6 kinase;;PDGF
              Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->90 kDa ribosomal protein S6 kinase;;PDGF
e;receptor;metalloprotease;serine protease;metalloprotease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion mo

ular matrix protein

ctor;DNA helicase;helicase
             Beta2 adrenergic receptor signaling pathway->ER-type Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->ER-type C




er/carrier protein




otein;dehydrogenase;reductase
iption factor;DNA binding protein
x glycoprotein
              General transcription by RNA polymerase I->PTRF;;

              Axon guidance mediated by semaphorins->Semaphorin 3A;;
              Axon guidance mediated by semaphorins->Semaphorin 4D;;
 signaling molecule

erine protease

              Blood coagulation->Antithrombin III;;
              Blood coagulation->heparin cofactor II;;




              Wnt signaling pathway->secreted frizzled-related protein;;Angiogenesis->Frizzled-Related Protein;;;




ne/threonine protein kinase;non-receptor serine/threonine protein kinase




             p53 pathway feedback loops 2->SIAH-1;;p53 pathway->Seven in absentia homolog 1;;Wnt signaling pathway->Seven in absen
 signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;cell adhesion molecule
 signaling molecule;immunoglobulin receptor superfamily;immunoglobulin receptor superfamily;cell adhesion molecule
             Huntington disease->Sin3A;;p53 pathway->Sin3;;;
             Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein 1;;
             p53 pathway->Sirtuin;;

ier protein;transfer/carrier protein




sporter;cation transporter
              Adrenaline and noradrenaline biosynthesis->amine translocator;;
ular matrix protein

              Wnt signaling pathway->Switched/Sucrose Non Fermentation;;
              Wnt signaling pathway->Switched/Sucrose Non Fermentation;;
              Wnt signaling pathway->Switched/Sucrose Non Fermentation;;




 iption factor;DNA binding protein
king regulatory protein
king regulatory protein

ctor;zinc finger transcription factor;DNA binding protein

              Vasopressin synthesis->Signal Peptidase;;Endothelin signaling pathway->signal peptidase;;;


tor microtubule binding protein




 inhibitor;calcium-binding protein
               FGF signaling pathway->sprouty;;EGF receptor signaling pathway->SPRY;;EGF receptor signaling pathway->sprouty;;;;


tracellular signaling cascade;cell surface receptor linked signal transduction
protein;calcium-binding protein
r;nucleic acid binding

              EGF receptor signaling pathway->signal transducer and activator of transcription;;p53 pathway feedback loops 2->Myc;;Oxidati


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

              Cytoskeletal regulation by Rho GTPase->Stathmin;;


              Parkinson disease->Syntaxin;;Adrenaline and noradrenaline biosynthesis->N-ethylmaleimide-sensitive factor attachment protei

             Thyrotropin-releasing hormone receptor signaling pathway->SNARE COMPLEX;;Muscarinic acetylcholine receptor 2 and 4 sign
             Oxidative stress response->MAP Kinase Phosphatases;;
             Oxidative stress response->MAP Kinase Phosphatases;;
ctor;DNA binding protein
 r;nucleic acid binding

 ;DNA binding protein


g factor;ribosomal protein
               Synaptic_vesicle_trafficking->Synaptophysin;;




 r;nucleic acid binding




               Apoptosis signaling pathway->Bax inhibitor-1;;
 inding protein
ase;protein phosphatase

ne/threonine protein kinase;non-receptor serine/threonine protein kinase

otein;serine protease;serine protease
r;nucleic acid binding

              TGF-beta signaling pathway->Transforming growth factor beta;;




receptor;receptor

 r;receptor;DNA polymerase processivity factor




ription factor;DNA binding protein

;nucleotide kinase


               Wnt signaling pathway->Transducin-like Enhance of Split 1-3;;
               TGF-beta signaling pathway->Transforming growth factor beta;;
               Toll receptor signaling pathway->Toll-like receptor 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12;;
ription factor;DNA binding protein
erine protease
erine protease
x structural protein
              p53 pathway->KILLER/death receptor (DR)5;;Apoptosis signaling pathway->TRAIL-receptor;;;

             Apoptosis signaling pathway->Tumor necrosis factor receptor 1;;

inding protein
er/carrier protein
hway;JNK cascade;cell cycle;transmembrane receptor protein serine/threonine kinase signaling pathway;JNK cascade
e;cytoskeletal protein


ier protein;transfer/carrier protein
               DNA replication->DNA Topoisomerase;;

             Huntington disease->Tumor protein p53 inducible protein 3;;

             Huntington disease->P53 tumor suppressor phosphoprotein;;P53 pathway feedback loops 1->P53;;p53 pathway->p53;;p53 pat


             Thiamine metabolism->Thiamine kinase;;
nase receptor;tyrosine protein kinase receptor;protein kinase
ubule binding protein




e;cytoskeletal protein
erase;RNA binding protein
               Alzheimer disease-presenilin pathway->Capacitative calcium channels;;
               Alzheimer disease-presenilin pathway->Capacitative calcium channels;;
iption factor;nuclease
 signaling molecule;cell adhesion molecule
 signaling molecule;cell adhesion molecule

er/carrier protein




 x protein;actin family cytoskeletal protein;cell adhesion molecule
e family cytoskeletal protein




elix transcription factor;nucleic acid binding
               Formyltetrahydroformate biosynthesis->Thymidylate synthase;;Formyltetrahydroformate biosynthesis->Dihydrofolate reductase


              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;Ubiquitin proteasome pathway->Ubiquitin activating enzyme E1;;;
              Ubiquitin proteasome pathway->Ubiquitin-conjugating enzyme E2;;Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;

              Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;

king regulatory protein
              Nicotine degradation->UDP glycosyltransferase 2, member B7;;Nicotine degradation->UDP glycosytransferase 1, polypeptide A

              Nicotine degradation->UDP glycosyltransferase 2, member B7;;Nicotine degradation->UDP glycosytransferase 1, polypeptide A


             De novo pyrmidine ribonucleotides biosythesis->Orotidine-5-phosphate decarboxylase;;De novo pyrmidine ribonucleotides bios
             Axon guidance mediated by netrin->UNC-5;;
kinase activator

              Salvage pyrimidine ribonucleotides->Uridine phosphorylase;;
              Salvage pyrimidine ribonucleotides->Uracil phosphoribosyltransferase;;




;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;exoribonuclease;nuclease;esterase;cysteine protease


              Hypoxia response via HIF activation->Von Hippel Lindau protein;;
inding protein
 ntermediate filament




eceptor superfamily;immunoglobulin receptor superfamily
immunity protein
 x protein;cell adhesion molecule
                Blood coagulation->von Willebrand Factor;;Inflammation mediated by chemokine and cytokine signaling pathway->ExtraCellula




                Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Angiogenesis->Wingless-Type MMTV Integ
                Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathway->Win
                Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathway->Win


nding protein


ng;aminoacyl-tRNA synthetase
 r;chromatin/chromatin-binding protein




 iption factor;DNA binding protein

metalloprotease




 iption factor;DNA binding protein
 iption factor;DNA binding protein
 iption factor;DNA binding protein
ng;G-protein modulator




iption factor;nuclease
iption factor;nucleic acid binding




iption factor;nucleic acid binding

iption factor;nucleic acid binding
iption factor;DNA binding protein
->Actin;;Cytoskeletal regulation by Rho GTPase->Actin;;Wnt signaling pathway->NFAT Target Genes;;Cadherin signaling pathway->Filamen
->Actin;;Cytoskeletal regulation by Rho GTPase->Actin;;Wnt signaling pathway->NFAT Target Genes;;Cadherin signaling pathway->Filamen


;;Huntington disease->Actin;;;;




e salvage pathway->Deoxyadenosine deaminase;;;




;immunoglobulin superfamily cell adhesion molecule
Phenylacetaldehyde dehydrogenase;;;
Phenylacetaldehyde dehydrogenase;;;




olyposis Coli;;;




or 1;;Integrin signalling pathway->ADP ribosylation factor 6;;;;


ase->Rho-GTPase-activating proteins;;Angiogenesis->Rho GTPase;;VEGF signaling pathway->Rho GTPase;;;;;




g pathway->Actin related protein 2/3 complex;;Cytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;
g pathway->Actin related protein 2/3 complex;;Cytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;
;;Inflammation mediated by chemokine and cytokine signaling pathway->Actin related protein 2/3 complex;;Cytoskeletal regulation by Rho G
Rad3-related (ATR);;;




tein;;Huntington disease->Bcl-2-associated X protein;;;;


ne receptor 2 and 4 signaling pathway->acetylcholinesterase;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->acetylcholineste
ase B signaling cascade->Phosphatidylinositol 3-kinase;;PDGF signaling pathway->PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, AL
m ion channel;;Metabotropic glutamate receptor group III pathway->Calcium Channel;;Thyrotropin-releasing hormone receptor signaling pathw
naling pathway->Ca2+ channel;;Alzheimer disease-amyloid secretase pathway->L-type calcium channels;;Nicotinic acetylcholine receptor sig




mation mediated by chemokine and cytokine signaling pathway->Calcium/calModulin-dependent Kinase II;;;




 signaling cascade;synaptic transmission




 ps 2->cyclin G;;;;
ediated by Slit/Robo->Cell division cycle 42;;T cell activation->cdc42;;EGF receptor signaling pathway->Rac;;p38 MAPK pathway->cell divisio




->Uridylate kinase;;Salvage pyrimidine ribonucleotides->Cytidylate kinase;;;;
 ion channel;;

globulin superfamily cell adhesion molecule
ling pathway->ExtraCellular matrix protein;;;
ling pathway->ExtraCellular matrix protein;;;




nin;;Wnt signaling pathway->alpha-Catenin;;;;




ease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule
d pathway->Vitamin D 25-Hydroxylase;;;
d pathway->Vitamin D 25-Hydroxylase;;;




eceptor mediated signaling pathway->Aromatic L-amino acid decarboxylase;;Histamine synthesis->Histidine Decarboxylase;;5-Hydroxytrypta




olate reductase;;Folate biosynthesis->Dihydrofolate synthase;;;;
e mediated by semaphorins->CRMP 3-associated molecule;;Pyrimidine Metabolism->Dihydropyrimidinase;;;;




ogenesis->Dishelvelled;;;;
ogenesis->Dishelvelled;;;;

 non-receptor tyrosine protein kinase




2, 3, and 4;;Endothelin signaling pathway->Pre-pro endothelin 1, 2, 3, and 4;;Endothelin signaling pathway->Pro endothelin 1, 2, 3, and 4;;En
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat


;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signaling pathway-
;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signaling pathway-

heimer disease-presenilin pathway->Furin;;;;




nd DNA-damage-inducible, alpha;;;




ate receptor pathway->Glutamate receptor, ionotropic, AMPA 1;;Ionotropic glutamate receptor pathway->AMPA Receptor;;Ionotropic glutam
or;;Metabotropic glutamate receptor group III pathway->AMPA/Kainate Receptor;;Ionotropic glutamate receptor pathway->glutamate recepto
disease->N-methyl-d-aspartate receptor;;Ionotropic glutamate receptor pathway->NR3;;Metabotropic glutamate receptor group III pathway->
ription regulation by bZIP transcription factor->General transcription factor IIF, polypeptide 1, 74-KD;;;
and cytokine signaling pathway->Interferon gamma;;;




inositol 5-phosphatase;;PI3 kinase pathway->SHIP;;Insulin/IGF pathway-protein kinase B signaling cascade->SH2 domain-containing inosito




signaling pathway->Integrin;;;
cell activation->Lck;;;;

er disease-presenilin pathway->T-cell factor/lymphoid enhancer factor;;Wnt signaling pathway->T cell factor;;;;
pathway->Low-density lipoprotein receptor-related protein;;Alzheimer disease-presenilin pathway->LRP N-terminal fragment;;Alzheimer dise
athway->p38-delta mitogen-activated protein kinase;;EGF receptor signaling pathway->p38 MAP kinase;;Oxidative stress response->p38 MA
 signaling pathway->p38 MAP kinase;;Oxidative stress response->p38 MAP Kinase;;B cell activation->p38;;Parkinson disease->p38 MAPK;;
ating Protein Kinase-2 and 3;;Interleukin signaling pathway->Mitogen-activated protein kinase-activated protein kinase 2;;VEGF signaling pat




way->Matrix metalloprotease;;Plasminogen activating cascade->pro-Matrix metalloprotease 1;;Plasminogen activating cascade->Matrix meta




 endent Kinase II;;Parkinson disease->Calcium/calmodulin-dependent serine protein kinase;;;
 is viral oncogene homolog;;p53 pathway feedback loops 2->Myc;;Interleukin signaling pathway->c-Myc;;PDGF signaling pathway->c-Myc;;;;;
athway->NFAT Target Genes;;Nicotinic acetylcholine receptor signaling pathway->Myosin;;Cytoskeletal regulation by Rho GTPase->Myosin
choline receptor signaling pathway->Myosin;;Cytoskeletal regulation by Rho GTPase->Myosin light chain;;;;


hemokine and cytokine signaling pathway->Myosin light chain kinase;;;




globulin superfamily cell adhesion molecule




 gnaling pathway->Nuclear factor kappa-B;;;
s->dTDP kinase;;De novo purine biosynthesis->dADP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dCDP kinase;;De novo




globulin superfamily cell adhesion molecule




e mediated by Slit/Robo->Netrin;;;;
me modulator;cell adhesion molecule
m->Pyridoxamine phosphate oxidase;;PLP biosynthesis->Pyridoxine-5-phosphate oxidase;;Pyridoxal phosphate salvage pathway->Pyridoxam




sphatase 2A;;Wnt signaling pathway->Protein phosphatase 2A;;;;




thway->PKC;;Alzheimer disease-amyloid secretase pathway->Protein kinase C;;EGF receptor signaling pathway->PKC;;Histamine H1 recep
 vation->CD45;;;;




 TPase-activating protein 1;;


m and diacylglycerol-regulated guanine nucleotide exchange factor;;
or of G-protein signaling;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Regulator of G-protein sign




somal protein S6 kinase;;PDGF signaling pathway->p90RSK;;p53 pathway by glucose deprivation->S6K;;PI3 kinase pathway->S6K;;;;;
somal protein S6 kinase;;PDGF signaling pathway->p90RSK;;p53 pathway by glucose deprivation->S6K;;PI3 kinase pathway->S6K;;;;;
me modulator;cell adhesion molecule




or signaling pathway->ER-type Ca2+ channel;;;
aling pathway->Seven in absentia homolog 1;;p53 pathway feedback loops 2->SIAH-1;;;;;




TPase-activating protein 1;;
ng pathway->sprouty;;;;




eedback loops 2->Myc;;Oxidative stress response->v-myc myelocytomatosis viral oncogene homolog;;Angiogenesis->Signal Transducer an




nsitive factor attachment protein receptor;;;

etylcholine receptor 2 and 4 signaling pathway->N-ethylmaleimide-sensitive factor attachment protein receptor;;Dopamine receptor mediated
53;;p53 pathway->p53;;p53 pathway by glucose deprivation->p53;;P53 pathway feedback loops 1->Delta Np73;;p53 pathway feedback loops
hesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;De novo pyrimidine deoxyribonucleotide biosynthesis->Thymi


 quitin activating enzyme E1;;;
ay->Ubiquitin protein ligase E3;;;




 osytransferase 1, polypeptide A4;;;

 osytransferase 1, polypeptide A4;;;


 pyrmidine ribonucleotides biosythesis->Orotate phosphoribosyltransferase;;;
signaling pathway->ExtraCellular matrix protein;;;




s->Wingless-Type MMTV Integration Site Family;;Alzheimer disease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->W
sease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;
sease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;
rin signaling pathway->Filamentous F-actin;;Integrin signalling pathway->Actin;;Inflammation mediated by chemokine and cytokine signaling
rin signaling pathway->Filamentous F-actin;;Integrin signalling pathway->Actin;;Inflammation mediated by chemokine and cytokine signaling
2/3 complex;;;;
2/3 complex;;;;
ytoskeletal regulation by Rho GTPase->Actin related protein 2/3 complex;;;;;
ling pathway->acetylcholinesterase;;;;
OL 3-KINASE, CATALYTIC, ALPHA;;PI3 kinase pathway->p101;;p53 pathway feedback loops 2->PI3K;;p53 pathway->PI3-K;;Axon guidance
ormone receptor signaling pathway->Ca2+ channel;;Endogenous_cannabinoid_signaling->Voltage-dependent Ca channel;;Metabotropic glut
otinic acetylcholine receptor signaling pathway->Calcium Channel;;Oxytocin receptor mediated signaling pathway->Ca2+ channel;;Beta2 adr
p38 MAPK pathway->cell division cycle 42;;Inflammation mediated by chemokine and cytokine signaling pathway->Cell division cycle 42;;TGF
Decarboxylase;;5-Hydroxytryptamine biosynthesis->Aromatic L-amino acid decarboxylase;;;;;
ro endothelin 1, 2, 3, and 4;;Endothelin signaling pathway->Endothelin 1, 2, 3, and 4;;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;


or mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;
or mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;




PA Receptor;;Ionotropic glutamate receptor pathway->AMPA/Kainate Receptor;;;;;
or pathway->glutamate receptor, ionotropic, kainate 4;;Ionotropic glutamate receptor pathway->AMPA/Kainate Receptor;;;;;;
ate receptor group III pathway->N-methyl-D-aspartate Receptor;;Ionotropic glutamate receptor pathway->N-methyl-D-aspartate Receptor;;Mu
>SH2 domain-containing inositol 5-phosphatase 2;;;;
minal fragment;;Alzheimer disease-presenilin pathway->LRP intracellular fragment;;Alzheimer disease-presenilin pathway->LRP transmemb
ative stress response->p38 MAP Kinase;;B cell activation->p38;;Ras Pathway->p38 mitogen activated protein kinase;;p53 pathway feedback
arkinson disease->p38 MAPK;;Ras Pathway->p38 mitogen activated protein kinase;;p53 pathway feedback loops 2->p38 MAPK;;JAK/STAT
n kinase 2;;VEGF signaling pathway->Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 and 3;;Ras Pathway->Mitogen activated




ctivating cascade->Matrix metalloprotease 13;;Plasminogen activating cascade->pro-matrix metalloprotease 13;;;;;;
F signaling pathway->c-Myc;;;;;;
ation by Rho GTPase->Myosin light chain;;;;;
nthesis->dCDP kinase;;De novo pyrmidine ribonucleotides biosythesis->UDP kinase;;De novo pyrmidine ribonucleotides biosythesis->CDP ki
te salvage pathway->Pyridoxamine-5-phosphate oxidase;;;;;




way->PKC;;Histamine H1 receptor mediated signaling pathway->PKC;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->Protein
ay->Regulator of G-protein signaling;;;




 kinase pathway->S6K;;;;;
 kinase pathway->S6K;;;;;
genesis->Signal Transducer and Activator of Transcription 1;;PDGF signaling pathway->STAT;;Ras Pathway->Signal transducer and activato




r;;Dopamine receptor mediated signaling pathway->SNARE Complex;;Opioid proopiomelanocortin pathway->SNARE COMPLEX;;Nicotinic a
73;;p53 pathway feedback loops 2->p53;;p53 pathway->p53;;P53 pathway feedback loops 1->P73DeltaN;;;;;;;;;
nucleotide biosynthesis->Thymidylate synthase;;Folate biosynthesis->Dihydrofolate synthase;;;;;;
ein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;;
site family member;;;;
site family member;;;;
emokine and cytokine signaling pathway->F-actin;;Huntington disease->Actin;;;;;;;;;
emokine and cytokine signaling pathway->F-actin;;Huntington disease->Actin;;;;;;;;;
pathway->PI3-K;;Axon guidance mediated by netrin->Phosphotidylinositol 3-kinase;;Endothelin signaling pathway->phosphatidylinositol 3-kina
 Ca channel;;Metabotropic glutamate receptor group II pathway->Calcium Channel;;Ionotropic glutamate receptor pathway->Calcium Chann
way->Ca2+ channel;;Beta2 adrenergic receptor signaling pathway->Ca2+ channel;;;;;;;
way->Cell division cycle 42;;TGF-beta signaling pathway->Ras-GTP;;Cytoskeletal regulation by Rho GTPase->Cell division cycle 42;;Axon gu
e Receptor;;;;;;
ethyl-D-aspartate Receptor;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->N-methyl-D-aspartate Receptor;;;;;;;
nilin pathway->LRP transmembrane fragment;;Wnt signaling pathway->Low density lipoprotein receptor related protein;;;;;;;
  kinase;;p53 pathway feedback loops 2->p38 MAPK;;Interferon-gamma signaling pathway->Serine kinase;;TGF-beta signaling pathway->P3
oops 2->p38 MAPK;;JAK/STAT signaling pathway->Serine kinase;;p38 MAPK pathway->p38-alpha mitogen-activated protein kinase;;Interfer
 s Pathway->Mitogen activated protein kinase activated protein kinase;;p38 MAPK pathway->MAPK-activated protein kinase 2;;;;;;;
ucleotides biosythesis->CDP kinase;;De novo pyrimidine deoxyribonucleotide biosynthesis->dUDP kinase;;De novo purine biosynthesis->dG
d 3 signaling pathway->Protein kinase C;;VEGF signaling pathway->Protein Kinase C;;Angiogenesis->Protein Kinase C;;FGF signaling pathw
>Signal transducer and activator of transcription;;Interleukin signaling pathway->Signal transducers and activators of transcription;;Interferon




SNARE COMPLEX;;Nicotinic acetylcholine receptor signaling pathway->N-ethylmaleimide-sensitive factor attachment protein receptor;;Corto
way->phosphatidylinositol 3-kinase;;;;;;;;;
eptor pathway->Calcium Channel;;GABA-B_receptor_II_signaling->Voltage-dependent Ca channel;;;;;;;;
>Cell division cycle 42;;Axon guidance mediated by netrin->Cell division cycle 42;;TGF-beta signaling pathway->Ras-GDP;;Ras Pathway->C
ate Receptor;;;;;;;
ed protein;;;;;;;
GF-beta signaling pathway->P38;;FGF signaling pathway->p38 MAP kinase;;Integrin signalling pathway->Extracellular signal-regulated kinas
ctivated protein kinase;;Interferon-gamma signaling pathway->Serine kinase;;TGF-beta signaling pathway->P38;;Toll receptor signaling path
 protein kinase 2;;;;;;;
e novo purine biosynthesis->dGDP kinase;;;;;;;;;
Kinase C;;FGF signaling pathway->PKC;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Protein kin
ators of transcription;;Interferon-gamma signaling pathway->Signal transducers and activaotrs of transcription 1;;Oxidative stress response->




achment protein receptor;;Cortocotropin releasing factor receptor signaling pathway->SNARE COMPLEX;;5HT2 type receptor mediated sign
y->Ras-GDP;;Ras Pathway->Cdc42;;;;;;;;;;;;;
acellular signal-regulated kinase;;;;;;;;;;;;
38;;Toll receptor signaling pathway->p38;;VEGF signaling pathway->p38 Mitogen-Activated Protein Kinase;;FGF signaling pathway->p38 MA
mediated pathway->Protein kinase C;;Endothelin signaling pathway->protein kinase c;;Oxytocin receptor mediated signaling pathway->PKC
1;;Oxidative stress response->signal transducer and activator of transcription 1;;JAK/STAT signaling pathway->Signal transducers and activ




T2 type receptor mediated signaling pathway->SNARE Complex;;Beta3 adrenergic receptor signaling pathway->SNARE COMPLEX;;Opioid
FGF signaling pathway->p38 MAP kinase;;Angiogenesis->p38 Mitogen-Activated Protein Kinase;;;;;;;;;;;;;;;;
diated signaling pathway->PKC;;5HT2 type receptor mediated signaling pathway->PKC;;;;;;;;;;;;;;
y->Signal transducers and activators of transcription;;Inflammation mediated by chemokine and cytokine signaling pathway->Signal transduc




ay->SNARE COMPLEX;;Opioid prodynorphin pathway->SNARE COMPLEX;;5HT1 type receptor mediated signaling pathway->SNARE Comp
aling pathway->Signal transducers and activaotrs of transcription;;;;;;;;;;;;




naling pathway->SNARE Complex;;Opioid proenkephalin pathway->SNARE COMPLEX;;Oxytocin receptor mediated signaling pathway->SN
mediated signaling pathway->SNARE COMPLEX;;5HT4 type receptor mediated signaling pathway->SNARE Complex;;Beta2 adrenergic rece
omplex;;Beta2 adrenergic receptor signaling pathway->SNARE COMPLEX;;Beta1 adrenergic receptor signaling pathway->SNARE COMPLE
ing pathway->SNARE COMPLEX;;5HT3 type
Z value   Gene Symbol   Accession   Gene Name                       GO Molecular Function
2.00      A2M           NM_000014                                   cytokine
                                    Alpha-2-macroglobulin;A2M;ortholog activity;serine-type endopeptidase inhibi
2.03      AASDH         NM_181806                                   ligase activity
                                    Acyl-CoA synthetase family member 4;AASDH;ortholog
2.24      ABCC2         NM_000392                                   ATPase activity, coupled to transmembrane move
                                    Canalicular multispecific organic anion transporter 1;ABCC2;ortholog
2.72      ABCC3         NM_003786                                   ATPase activity, coupled to transmembrane move
                                    Canalicular multispecific organic anion transporter 2;ABCC3;ortholog
-2.30     ABCC8         NM_000352                                   ATPase activity, coupled to transmembrane
                                    ATP-binding cassette transporter sub-family C member 8;ABCC8;ortholog move
2.60      ABCD3         NM_002858                                   transmembrane transporter activity
                                    ATP-binding cassette sub-family D member 3;ABCD3;ortholog
2.30      ABCG2         NM_004827                                   transmembrane transporter activity
                                    ATP-binding cassette sub-family G member 2;ABCG2;ortholog
2.07      ACAD10        NM_025247                                   oxidoreductase activity;transferase activity
                                    Acyl-CoA dehydrogenase family member 10;ACAD10;ortholog
2.63      ACE2          NM_021804                                   metallopeptidase activity
                                    Processed angiotensin-converting enzyme 2;ACE2;ortholog
2.75      ACOX2         NM_003500                                   oxidoreductase activity
                                    Peroxisomal acyl-coenzyme A oxidase 2;ACOX2;ortholog
-2.67     ACP1          NM_004300                                   phosphoprotein phosphatase activity;phosphopro
                                    Low molecular weight phosphotyrosine protein phosphatase;ACP1;ortholog
-2.76     ACSF2         NM_025149                                   ligase activity
                                    Acyl-CoA synthetase family member 2, mitochondrial;ACSF2;ortholog
2.07      ACVR1C        NM_145259                                   transmembrane receptor protein kinase activity;tr
                                    Activin receptor type-1C;ACVR1C;ortholog
-2.87     ACVR2         NM_001616                                   transmembrane receptor protein kinase activity;tr
                                    Activin receptor type-2A;ACVR2A;ortholog
-4.45     ADAMTS20      NM_025003                                   metallopeptidase activity
                                    A disintegrin and metalloproteinase with thrombospondin motifs 20;ADAMTS20;
-3.05     ADC           NM_052998                                   carboxy-lyase activity
                                    Arginine decarboxylase;ADC;ortholog
-2.92     ADCY9         NM_001116                                   adenylate cyclase activity
                                    Adenylate cyclase type 9;ADCY9;ortholog
-2.44     ADSS          NM_001126                                   ligase activity
                                    Adenylosuccinate synthetase isozyme 2;ADSS;ortholog
2.12      AEGP          XM_088463   Apical endosomal glycoprotein;MAMDC4;ortholog
-2.61     AES           NM_001130                                   transcription factor activity;transcription factor act
                                    Amino-terminal enhancer of split;AES;ortholog
-2.28     AFM           NM_001133   Afamin;AFM;ortholog
2.15      AFP           NM_001134   Alpha-fetoprotein;AFP;ortholog
2.69      AIFM3         NM_144704                                   oxidoreductase activity
                                    Apoptosis-inducing factor 3;AIFM3;ortholog
2.37      AKAP1         NM_003488                                   receptor binding
                                    A kinase anchor protein 1, mitochondrial;AKAP1;ortholog
2.79      AKAP10        NM_007202                                   protein binding;kinase activator
                                    A kinase anchor protein 10, mitochondrial;AKAP10;ortholog activity;kinase reg
2.18      ALDH1B1       NM_000692                                   oxidoreductase activity
                                    Aldehyde dehydrogenase X, mitochondrial;ALDH1B1;ortholog
-2.42     ALOXE3        NM_021628                                   oxidoreductase activity
                                    Epidermis-type lipoxygenase 3;ALOXE3;ortholog
-3.72     ALS2CR2       NM_018571                                            kinase activity
                                    STE20-related kinase adapter protein beta;STRADB;ortholog
2.19      AMBRA1        XM_370618   Activating molecule in BECN1-regulated autophagy protein 1;AMBRA1;ortholog
2.76      AMN1          NM_207337   Protein AMN1 homolog;AMN1;ortholog
-2.29     AMY2A         NM_000699                                   amylase activity
                                    Pancreatic alpha-amylase;AMY2A;ortholog
2.98      ANGPT2        NM_001147   Angiopoietin-2;ANGPT2;ortholog  receptor binding;kinase regulator activity
2.34      ANGPTL2       NM_012098                                   receptor binding
                                    Angiopoietin-related protein 2;ANGPTL2;ortholog
3.13      ANKRD43       NM_175873   Ankyrin repeat domain-containing protein 43;ANKRD43;ortholog
-2.80     ANP32A        NM_006305                                   protein binding;phosphatase inhibitor activity;phos
                                    Acidic leucine-rich nuclear phosphoprotein 32 family member A;ANP32A;ortholo
2.07      AP3M1         NM_012095   AP-3 complex subunit mu-1;AP3M1;ortholog
2.78      APOA1         NM_000039                                   lipid transporter activity;transmembrane transport
                                    Apolipoprotein A-I(1-242);APOA1;ortholog
-3.44     APOA4         NM_000482                                   lipid transporter activity;transmembrane transport
                                    Apolipoprotein A-IV;APOA4;ortholog
2.31      APOL2         NM_030882                                   lipid
                                    Apolipoprotein L2;APOL2;ortholog transporter activity;transmembrane transport
2.13      APPL          NM_012096                                   nucleic acid binding;protein binding;small GTPas
                                    DCC-interacting protein 13-alpha;APPL1;ortholog
-2.20     AQP1          NM_000385   Aquaporin-1;AQP1;ortholog transmembrane transporter activity
2.22      AQP11         NM_173039   Aquaporin-11;AQP11;ortholog
2.10      AR,AREG       NM_001657   Amphiregulin;AREG;ortholog growth factor activity
2.55      ARHGEF10L     NM_018125                                   cysteine-type peptidase activity
                                    Rho guanine nucleotide exchange factor 10-like protein;ARHGEF10L;ortholog
-2.59     ARHGEF17      NM_014786   Rho guanine nucleotide exchange factor 17;ARHGEF17;ortholog
2.42      ARHGEF9       XM_377014                                   protein binding;small GTPase regulator activity;gu
                                    Rho guanine nucleotide exchange factor 9;ARHGEF9;ortholog
3.24      ARID1A        NM_018450                                   nucleic acid binding;chromatin binding
                                    AT-rich interactive domain-containing protein 1A;ARID1A;ortholog
2.40      ARMCX3        NM_016607   Armadillo repeat-containing X-linked protein 3;ARMCX3;ortholog
-3.01   ARPP-21     NM_016300   cAMP-regulated phosphoprotein 21;ARPP21;ortholog
-2.22   ARR3        NM_004312   Arrestin-C;ARR3;ortholog        protein binding
3.53    ARRDC2      NM_015683   Arrestin domain-containing protein 2;ARRDC2;ortholog
-3.34   ARSA        NM_000487                                   hydrolase activity
                                Arylsulfatase A component C;ARSA;ortholog
2.31    ASB2        NM_016150   Ankyrin repeat and SOCS box protein 2;ASB2;ortholog
2.45    ASB6        NM_017873   Ankyrin repeat and SOCS box protein 6;ASB6;ortholog
2.25    ASGR2       NM_001181                                   receptor activity
                                Asialoglycoprotein receptor 2;ASGR2;ortholog
2.47    ASIP        NM_001672                                   receptor
                                Agouti-signaling protein;ASIP;ortholog binding
2.71    ATF6B       NM_004381   Processed cyclic AMP-dependent transcription factor ATF-6 beta;ATF6B;ortholo
-2.60   ATP5H       NM_006356   ATP synthase subunit d, mitochondrial;ATP5H;ortholog
2.69    ATP6AP1L    XM_043989                                   hydrolase activity;cation transmembrane
                                V-type proton ATPase subunit S1-like protein;VAS1L_HUMAN;ortholog transpor
2.64    ATP6V0A1    NM_005177                                    subunit a isoform 1;ATP6V0A1;ortholog
                                V-type proton ATPase 116 kDacation transmembrane transporter activity;hydrog
-2.57   ATP6V0E     NM_003945                                   nucleotide phosphatase
                                V-type proton ATPase subunit e 1;ATP6V0E1;ortholog activity;nucleotide phosp
3.08    ATP6V1D     NM_015994                                   hydrolase activity;cation transmembrane transpor
                                V-type proton ATPase subunit D;ATP6V1D;ortholog
2.46    B7H3        NM_025240   CD276 antigen;CD276;ortholog
3.43    BAIAP2L2    NM_025045                                   receptor activity
                                Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2;BAIAP
2.80    BARD1       NM_000465   BRCA1-associated RING domain protein 1;BARD1;ortholog
-2.00   BBAP        NM_138287                                   transcription factor activity;transcription factor act
                                Protein deltex-3-like;DTX3L;ortholog
2.43    BBS10       NM_024685   Bardet-Biedl syndrome 10 protein;BBS10;ortholog
3.39    BFAR        NM_016561   Bifunctional apoptosis regulator;BFAR;ortholog
2.67    BHMT2       NM_017614                                   oxidoreductase activity;methyltransferase activity
                                Betaine--homocysteine S-methyltransferase 2;BHMT2;ortholog
2.19    BIN3        NM_018688   Bridging integrator 3;BIN3;ortholog
2.27    BIRC2       NM_001166                                   protein binding;peptidase inhibitor activity
                                Baculoviral IAP repeat-containing protein 2;BIRC2;ortholog
3.41    BOLA1       NM_016074   BolA-like protein 1;BOLA1;ortholog
-2.36   BPY1        NM_004679   Testis-specific basic protein Y 1;VCY1B;ortholog
-2.18   BRCA1       NM_007294                                   transcription factor activity;transcription factor act
                                Breast cancer type 1 susceptibility protein;BRCA1;ortholog
-4.17   BSDC1       NM_018045   BSD domain-containing protein 1;BSDC1;ortholog
2.48    BTAF1       NM_003972                                   DNA helicase activity;nucleic
                                TATA-binding protein-associated factor 172;BTAF1;ortholog acid binding
-2.56   BTNL3       NM_006707   Butyrophilin-like protein 3;BTNL3;ortholog
-3.17   C10ORF10    NM_007021   Protein DEPP;DEPP;ortholog
2.41    C10ORF114   XM_378215   Putative uncharacterized protein C10orf114;C10orf114;ortholog
2.46    C10ORF125   NM_198472   Protein fucU homolog;C10orf125;ortholog
2.74    C10ORF53    NM_182554   Uncharacterized protein C10orf53;C10orf53;ortholog
-2.42   C11ORF34    XM_370657   Placenta-expressed transcript 1 protein;PLET1;ortholog
2.51    C11ORF36    NM_173590   Uncharacterized protein C11orf36;C11orf36;ortholog
-3.18   C11ORF61    NM_024631   Uncharacterized protein C11orf61;C11orf61;ortholog
2.47    C11ORF93    XM_071712   uncharacterized protein C11orf93
-2.82   C12ORF49    NM_024738   UPF0454 protein C12orf49;C12orf49;ortholog
-2.81   C12ORF68    XM_370691   Uncharacterized protein C12orf68;C12orf68;ortholog
2.30    C13ORF31    NM_153218   UPF0124 protein C13orf31;C13orf31;ortholog
2.31    C13ORF33    NM_032849   Uncharacterized protein C13orf33;C13orf33;ortholog
2.01    C14ORF109   XM_058628   UPF0694 transmembrane protein C14orf109;C14orf109;ortholog
2.04    C14ORF116   NM_018589                                   transcription
                                Forkhead box protein N3;FOXN3;ortholog factor activity;transcription factor act
-2.77   C14ORF172   NM_152307                                   methyltransferase subunit
                                tRNA (adenine-N(1)-)-methyltransferase catalytic activity TRM61;TRM61;ortholo
-3.48   C14ORF2     NM_004894   6.8 kDa mitochondrial proteolipid;MP68;ortholog
2.97    C15ORF5     NM_030944   Uncharacterized protein C15orf5;C15orf5;ortholog
-2.41   C17ORF105   XM_208990   uncharacterized protein C17orf105
-3.76   C17ORF39    NM_024052   Uncharacterized protein C17orf39;C17orf39;ortholog
-2.31   C17ORF67    XM_378687   Uncharacterized protein C17orf67;C17orf67;ortholog
-2.49   C1ORF111   NM_182581   Uncharacterized protein C1orf111;C1orf111;ortholog
4.14               NM_033418
        C1ORF156,ASTP2         UPF0558 protein C1orf156;C1orf156;ortholog
-3.03   C1ORF227   XM_086616   UPF0732 protein C1orf227
-2.97   C1ORF95    XM_375849   Uncharacterized membrane protein C1orf95;C1orf95;ortholog
-2.50   C20ORF106 XM_371401    Uncharacterized protein C20orf106;C20orf106;ortholog
-2.97   C20ORF18   NM_006462                                  ubiquitin-protein ligase activity
                               RanBP-type and C3HC4-type zinc finger-containing protein 1;RBCK1;ortholog
-1.98   C21ORF121 NM_198078    Uncharacterized protein C21orf121;C21orf121;ortholog
-2.74   C21ORF123 NM_199175    Uncharacterized protein C21orf123;C21orf123;ortholog
2.17    C21ORF13   NM_152505   Lebercilin-like protein;LCA5L;ortholog
-2.18   C21ORF5    NM_005128   Protein dopey-2;DOPEY2;ortholog
-2.15   C22ORF18   NM_024053   Centromere protein M;CENPM;ortholog
2.50    C2ORF73    XM_059377   Uncharacterized protein C2orf73;C2orf73;ortholog
-3.14   C2ORF81    XM_371503   Uncharacterized protein C2orf81;C2orf81;ortholog
-3.69   C3ORF6     NM_174908   Coiled-coil domain-containing protein 50;CCDC50;ortholog
-2.04   C3ORF70    XM_211871   UPF0524 protein C3orf70;C3orf70;ortholog
3.06    C5ORF6     NM_016605   Protein FAM53C;FAM53C;ortholog
3.07    C6ORF152   NM_181714   Lebercilin;LCA5;ortholog
-2.43   C6ORF157   NM_198920   Ubiquitin-conjugating enzyme E2C-binding protein;UBE2CBP;ortholog
-2.41   C6ORF65    NM_152731   Coiled-coil domain-containing protein C6orf65;C6orf65;ortholog
-2.12   C6ORF85    NM_021945                                  ATPase activity, coupled
                               Solute carrier family 22 member 23;SLC22A23;ortholog to transmembrane move
-3.68   C7ORF19    NM_032831   Protein orai-2;ORAI2;ortholog
-2.07   C7ORF25    NM_024054   UPF0415 protein C7orf25;C7orf25;ortholog
-2.67   C7ORF3     XM_049384                                  nuclease activity;mRNA binding
                               Nucleolar MIF4G domain-containing protein 1;NOM1;ortholog
2.34    C7ORF34    NM_178829   Uncharacterized protein C7orf34;C7orf34;ortholog
2.76    C8A        NM_000562   Complement component C8 alpha chain;C8A;ortholog
-2.73   C8ORF1     NM_004337   Oxidative stress-induced growth inhibitor 2;OSGIN2;ortholog
2.06    C8ORF41    NM_025115   Uncharacterized protein C8orf41;C8orf41;ortholog
2.56    C9ORF115   XM_059972                                  hydrolase activity, acting on ester bonds
                               Probable peptidyl-tRNA hydrolase;PTRH1;ortholog
2.14    C9ORF125   NM_032342   Transmembrane protein C9orf125;C9orf125;ortholog
2.36    C9ORF4     XM_378078   Uncharacterized protein C9orf4;C9orf4;ortholog
3.06    C9ORF81    XM_095991   Centrosomal protein of 78 kDa;CEP78;ortholog
-2.02   CA8        NM_004056   Carbonic anhydrase-related protein;CA8;ortholog
-1.95   CACNB1     NM_000723                                  voltage-gated calcium channel activity;voltage-ga
                               Voltage-dependent L-type calcium channel subunit beta-1;CACNB1;ortholog
2.02    CAPN2      NM_001748                                  cysteine-type
                               Calpain-2 catalytic subunit;CAPN2;ortholog peptidase activity;calcium ion bindin
1.99    CARD14     NM_024110   Caspase recruitment domain-containing protein 14;CARD14;ortholog
2.26    CART       NM_004291   CART(42-89);CARTPT;ortholog
2.66    CASC1      NM_018272   Cancer susceptibility candidate protein 1;CASC1;ortholog
2.98    CBLN1      NM_004352                                  neuropeptide hormone activity
                               [des-Ser1]-cerebellin;CBLN1;ortholog
-2.92   CBX4       NM_003655                                  transcription factor activity;chromatin binding;tran
                               E3 SUMO-protein ligase CBX4;CBX4;ortholog
-2.86   CCDC134    NM_024821   Coiled-coil domain-containing protein 134;CCDC134;ortholog
-2.33   CCDC42     NM_144681   Coiled-coil domain-containing protein 42A;CCDC42;ortholog
2.43    CCDC53     NM_016053   Coiled-coil domain-containing protein 53;CCDC53;ortholog
2.89    CCDC57     NM_198082   Coiled-coil domain-containing protein 57;CCDC57;ortholog
3.00    CCDC6      NM_005436   Coiled-coil domain-containing protein 6;CCDC6;ortholog
2.57    CCDC70     NM_031290   Coiled-coil domain-containing protein 70;CCDC70;ortholog
-2.47   CCDC92     NM_025140   Coiled-coil domain-containing protein 92;CCDC92;ortholog
-4.05   CCL4       NM_002984   MIP-1-beta(3-69);CCL4;ortholog chemokine activity
2.14    CCNG2      NM_004354   Cyclin-G2;CCNG2;ortholog       protein binding;kinase activator activity;kinase reg
3.22    CCNT1      NM_001240   Cyclin-T1;CCNT1;ortholog       transcription factor activity;protein binding;kinase
2.57    CD209      NM_021155   CD209 antigen;CD209;ortholog    receptor activity
2.75    CD47       NM_001777                                   receptor activity;protein binding;small GTPase reg
                               Leukocyte surface antigen CD47;CD47;ortholog
2.56    CD81       NM_004356   CD81 antigen;CD81;ortholog receptor binding
2.51    CD83       NM_004233   CD83 antigen;CD83;ortholog
3.13    CDC25C     NM_001790                                   3;CDC25C;ortholog
                               M-phase inducer phosphatase phosphoprotein phosphatase activity;phosphopro
2.47    CDH17      NM_004063   Cadherin-17;CDH17;ortholog calcium ion binding
-2.09   CDH19      NM_021153   Cadherin-19;CDH19;ortholog calcium ion binding
2.19    CDH28      NM_152750                                   calcium ion
                               Cadherin-like protein 28;CDH28;ortholog binding
-2.73   CDH29      XM_371639                                   calcium ion
                               Cadherin-like protein 29;CDH29;ortholog binding
2.39    CDK5RAP1   NM_016082   CDK5 regulatory subunit-associated protein 1;CDK5RAP1;ortholog
2.07    CENTG3     NM_031946                                    and PH domain-containing protein 3;AGAP3;orth
                               Arf-GAP, GTPase, ANK repeatnucleic acid binding;protein binding;small GTPas
-2.56   CETN2      NM_004344   Centrin-2;CETN2;ortholog        calcium ion binding;calmodulin binding
-2.28   CGRRF1     NM_006568   Cell growth regulator with RING finger domain protein 1;CGRRF1;ortholog
-3.29   CH25H      NM_003956                                   oxidoreductase
                               Cholesterol 25-hydroxylase;CH25H;ortholog activity
2.84    CHFR       NM_018223                                   ubiquitin-protein ligase activity
                               E3 ubiquitin-protein ligase CHFR;CHFR;ortholog
2.10    CHIC2      NM_012110   Cysteine-rich hydrophobic domain 2 protein;CHIC2;ortholog
-3.12   CHN1       NM_001822   N-chimaerin;CHN1;ortholog protein binding;small GTPase regulator activity
-2.53   CHN2       NM_004067   Beta-chimaerin;CHN2;orthologprotein binding;small GTPase regulator activity
-2.34   CHRAC1     NM_017444                                   DNA-directed DNA polymerase
                               Chromatin accessibility complex protein 1;CHRAC1;ortholog activity;transcripti
3.41    CHRNB4     NM_000750                                   acetylcholine receptor activity;cation
                               Neuronal acetylcholine receptor subunit beta-4;CHRNB4;ortholog transmembr
-2.54   CHST13     NM_152889                                   13;CHST13;ortholog
                               Carbohydrate sulfotransferase transferase activity
2.73    CIG5       NM_080657   Radical S-adenosyl methionine domain-containing protein 2;RSAD2;ortholog
2.09    CKAP2L     NM_152515                                   structural constituent of cytoskeleton
                               Cytoskeleton-associated protein 2-like;CKAP2L;ortholog
3.13    CKM        NM_001824                                   amino
                               Creatine kinase M-type;CKM;ortholog acid kinase activity
3.31    CLCN5      NM_000084                                   anion channel
                               Chloride channel protein 5;CLCN5;ortholog activity
2.30    CLDN3      NM_001306   Claudin-3;CLDN3;ortholog
2.35    CLDN5      NM_003277   Claudin-5;CLDN5;ortholog
2.70    CLIC3      NM_004669                                   transferase activity;anion
                               Chloride intracellular channel protein 3;CLIC3;ortholog channel activity
3.11    CLN3       NM_000086   Battenin;CLN3;ortholog
-2.09   CLPX       NM_006660   ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial;CLPX
2.02    CMTM1      NM_052999   CKLF-like MARVEL transmembrane domain-containing protein 1;CMTM1;orthol
2.24    CNGA1      NM_000087                                   receptor activity;voltage-gated potassium channe
                               cGMP-gated cation channel alpha-1;CNGA1;ortholog
1.95    CNGB3      NM_019098                                   receptor activity;voltage-gated potassium channe
                               Cyclic nucleotide-gated cation channel beta-3;CNGB3;ortholog
2.33    CNNM2      NM_017649   Metal transporter CNNM2;CNNM2;ortholog
2.92    CNOT2      NM_014515                                   transcription factor activity;transcription factor act
                               CCR4-NOT transcription complex subunit 2;CNOT2;ortholog
2.66    CNOT4      NM_013316                                   transcription factor activity;transcription factor act
                               CCR4-NOT transcription complex subunit 4;CNOT4;ortholog
2.13    COL15A1    NM_001855   Endostatin;COL15A1;ortholog extracellular matrix structural constituent
2.06    COL18A1    NM_030582   Endostatin;COL18A1;ortholog extracellular matrix structural constituent
-3.09   COL28A1    XM_295195   Collagen alpha-1(XXVIII) chain;COL28A1;ortholog
3.44    COL4A1     NM_001845   Collagen alpha-1(IV) chain;COL4A1;ortholog
2.90    COL4A2     NM_001846   Canstatin;COL4A2;ortholog extracellular matrix structural constituent
2.18    COL4A6     NM_001847                                   extracellular matrix structural constituent
                               Collagen alpha-6(IV) chain;COL4A6;ortholog
2.24    COMMD10    NM_016144   COMM domain-containing protein 10;COMMD10;ortholog
2.66    CORO1B     NM_020441   Coronin-1B;CORO1B;ortholog structural constituent of cytoskeleton;actin binding
2.69    CPA1       NM_001868                                   metallopeptidase activity
                               Carboxypeptidase A1;CPA1;ortholog
2.99    CPN1       NM_001308                                   metallopeptidase activity
                               Carboxypeptidase N catalytic chain;CPN1;ortholog
-2.86   CREG       NM_003851   Protein CREG1;CREG1;ortholog
2.04    CRELD1     NM_015513   Cysteine-rich with EGF-like domain protein 1;CRELD1;ortholog
2.47    CRIM1      NM_016441   Processed cysteine-rich motor neuron 1 protein;CRIM1;ortholog
-4.19   CRIP1       NM_001311                                     structural
                                Cysteine-rich protein 1;CRIP1;ortholog constituent of cytoskeleton
2.47    CRK         NM_005206   Proto-oncogene C-crk;CRK;ortholog
2.01    CXCL17      NM_198477   VEGF co-regulated chemokine 1;CXCL17;ortholog
2.04    CXORF20     NM_153346   Uncharacterized protein CXorf20;CXorf20;ortholog
2.58    CXORF41     NM_173494   Uncharacterized protein CXorf41;CXorf41;ortholog
-2.03   CXORF66     XM_298053   uncharacterized protein CXorf662
3.08    CYB5        NM_001914                                     o
                                Cytochrome b5;CYB5A;orthologxidoreductase activity
3.02    CYLD        NM_015247                                     structural constituent of ribosome;nucleic acid bin
                                Probable ubiquitin carboxyl-terminal hydrolase CYLD;CYLD;ortholog
-3.51   CYP2D6      NM_000106                                     oxidoreductase activity
                                Cytochrome P450 2D6;CYP2D6;ortholog
-2.66               NM_021006
        D17S1718,SCYA3L1        LD78-beta(5-70);CCL3L3;ortholog   chemokine activity
-2.11   DBI         NM_020548                                     protein
                                Acyl-CoA-binding protein;DBI;ortholog binding;enzyme inhibitor activity
-1.97   DCST2       NM_144622   DC-STAMP domain-containing protein 2;DCST2;ortholog
3.53    DDC         NM_000790                                     carboxy-lyase activity
                                Aromatic-L-amino-acid decarboxylase;DDC;ortholog
-2.45   DDX51       NM_175066                                     RNA helicase activity;nucleic acid binding
                                ATP-dependent RNA helicase DDX51;DDX51;ortholog
-2.59   DDX55       NM_020936                                     RNA helicase activity;nucleic acid binding
                                ATP-dependent RNA helicase DDX55;DDX55;ortholog
2.91    DERP6       NM_015362   Dermal papilla-derived protein 6;DERP6;ortholog
2.27    DHDH        NM_014475                                     oxidoreductase activity
                                Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;DHDH;ortholog
2.68    DIRC2       NM_032839                                     transmembrane transporter activity
                                Disrupted in renal carcinoma protein 2;DIRC2;ortholog
2.28    DISC1       NM_018662   Disrupted in schizophrenia 1 protein;DISC1;ortholog
-2.83   DIXDC1      XM_290496   Dixin;DIXDC1;ortholog             receptor binding;enzyme regulator activity
-2.33   DLG4        NM_001365   Disks large homolog 4;DLG4;ortholog
2.05    DLGAP1      NM_004746   Disks large-associated protein 1;DLGAP1;ortholog
-2.73   DLGAP3      XM_035601   Disks large-associated protein 3;DLGAP3;ortholog
3.68    DMGDH       NM_013391                                     oxidoreductase activity
                                Dimethylglycine dehydrogenase, mitochondrial;DMGDH;ortholog
3.21    DNAJD1      NM_013238   DnaJ homolog subfamily C member 15;DNAJC15;ortholog
-2.80   DND1        NM_194249                                     RNA binding
                                Dead end protein homolog 1;DND1;ortholog
-2.03   DOCK8       NM_203447                                     protein binding;small
                                Dedicator of cytokinesis protein 8;DOCK8;ortholog GTPase regulator activity;gu
2.05    DPEP2       NM_022355   Dipeptidase 2;DPEP2;ortholog metallopeptidase activity
-2.39   DPP9        NM_139159                                     serine-type peptidase activity
                                Dipeptidyl peptidase 9;DPP9;ortholog
2.91    DPYS        NM_001385   Dihydropyrimidinase;DPYS;ortholog hydrolase activity
-3.01   DRAM2       NM_178454   Transmembrane protein 77;TMEM77;ortholog
2.58    DSPP        NM_014208   Dentin sialoprotein;DSPP;ortholog
-2.17   DUSP26      NM_024025                                     phosphoprotein phosphatase
                                Dual specificity protein phosphatase 26;DUSP26;ortholog activity;phosphopro
2.14    DUSP3       NM_004090                                     phosphoprotein phosphatase activity;phosphopro
                                Dual specificity protein phosphatase 3;DUSP3;ortholog
-2.60   DUX4        NM_033178                                     transcription
                                Double homeobox protein 4;DUX4;ortholog factor activity;transcription factor act
-2.53   DXS9928E    NM_004699   Protein FAM50A;FAM50A;ortholog
2.24    DZIP1L      NM_173543                                     nucleic acid
                                Zinc finger protein DZIP1L;DZIP1L;orthologbinding
3.00    E2F4        NM_001950                                     transcription factor activity;transcription factor act
                                Transcription factor E2F4;E2F4;ortholog
2.52    ECHDC1      NM_018479                                     oxidoreductase activity;acetyltransferase activity;h
                                Enoyl-CoA hydratase domain-containing protein 1;ECHDC1;ortholog
-2.77   EDEM2       NM_018217                                     hydrolase activity
                                ER degradation-enhancing alpha-mannosidase-like 2;EDEM2;ortholog
-2.91   EEF1A2      NM_001958                                     translation factor activity, nucleic acid binding;tran
                                Elongation factor 1-alpha 2;EEF1A2;ortholog
2.42    EEF2        NM_001961   Elongation factor 2;EEF2;ortholog translation factor activity, nucleic acid binding;tran
2.60    EFNA5       NM_001962   Ephrin-A5;EFNA5;ortholog          receptor binding
3.64    EFNB1       NM_004429   Ephrin-B1;EFNB1;ortholog          receptor binding
2.83    EGFLAM      NM_152403   Pikachurin;EGFLAM;ortholog
-2.10   EGR1        NM_001964                                     transcription factor
                                Early growth response protein 1;EGR1;ortholog activity;transcription factor act
3.20    EHBP1L1     XM_170658                                     structural 1;EHBP1L1;ortholog
                                EH domain-binding protein 1-like protein constituent of cytoskeleton;actin binding
2.52    EIF2B1      NM_001414                                     isomerase alpha;EIF2B1;ortholog
                                Translation initiation factor eIF-2B subunit activity;translation initiation factor activ
3.99    EIF2C1      NM_012199                                     factor 2C factor activity, nucleic acid binding;tran
                                Eukaryotic translation initiation translation1;EIF2C1;ortholog
2.47    EIF3S2     NM_003757                                     factor 3 subunit I;EIF3I;ortholog
                               Eukaryotic translation initiation translation factor activity, nucleic acid binding;tran
-2.45   ELAVL2     NM_004432                                     RNA binding
                               ELAV-like protein 2;ELAVL2;ortholog
2.02    ELF4       NM_001421                                       Elf-4;ELF4;ortholog
                               ETS-related transcription factortranscription factor activity;receptor binding;transc
2.25    ELP3       NM_018091                                     acetyltransferase activity
                               Elongator complex protein 3;ELP3;ortholog
2.67    ENTPD8     NM_138793                                     nucleotide phosphatase activity;nucleotide phosp
                               Ectonucleoside triphosphate diphosphohydrolase 8;ENTPD8;ortholog
2.20    EPHB1      NM_004441                                     transmembrane receptor protein kinase activity;tr
                               Ephrin type-B receptor 1;EPHB1;ortholog
2.02    EPHB2      NM_004442                                     transmembrane receptor protein kinase activity;tr
                               Ephrin type-B receptor 2;EPHB2;ortholog
2.50    EPHB2      NM_004442                                     transmembrane receptor protein kinase activity;tr
                               Ephrin type-B receptor 2;EPHB2;ortholog
2.34    ERC1       NM_015064                                     protein binding;small GTPase regulator activity
                               ELKS/RAB6-interacting/CAST family member 1;ERC1;ortholog
2.04    ERN1       NM_001433   Endoribonuclease;ERN1;ortholog    protein kinase activity
1.99    ERO1L      NM_014584                                     oxidoreductase activity
                               ERO1-like protein alpha;ERO1L;ortholog
2.38    ETFA       NM_000126   Electron transfer flavoprotein subunit alpha, mitochondrial;ETFA;ortholog
3.20    ETV7       NM_016135                                     transcription
                               Transcription factor ETV7;ETV7;ortholog factor activity;receptor binding;transc
2.77    EXTL2      NM_001439                                     transferase
                               Processed exostosin-like 2;EXTL2;orthologactivity, transferring glycosyl groups
2.16    F2         NM_000506   Thrombin heavy chain;F2;ortholog  serine-type peptidase activity
-3.07   FAM11A     NM_032508   Transmembrane protein 185A;TMEM185A;ortholog
2.68    FAM133B    NM_152789   Protein FAM133B;FAM133B;ortholog
-2.73   FAM173A    NM_023933   Protein FAM173A;FAM173A;ortholog
2.43    FAM18B     NM_016078   Protein FAM18B;FAM18B;ortholog
2.65    FAM43A     NM_153690   Protein FAM43A;FAM43A;ortholog
-2.04   FAM57A     NM_024792   Protein FAM57A;FAM57A;ortholog
2.16    FANCD2     NM_033084   Fanconi anemia group D2 protein;FANCD2;ortholog
-2.57   FARSLA     NM_004461                                     alpha chain;FARSA;ortholog
                               Phenylalanyl-tRNA synthetase aminoacyl-tRNA ligase activity
-2.31   FASTKD1    NM_024622   FAST kinase domain-containing protein 1;FASTKD1;ortholog
-3.52   FASTKD5    NM_021826   FAST kinase domain-containing protein 5;FASTKD5;ortholog
-2.09   FBF1       XM_371079   Fas-binding factor 1;FBF1;ortholog
2.29    FBN2       NM_001999   Fibrillin-2;FBN2;ortholog         extracellular matrix structural constituent;calcium
-2.43   FBXL3A     NM_012158   F-box/LRR-repeat protein 3;FBXL3;ortholog
-2.03   FBXL3P     NM_012159   F-box/LRR-repeat protein 21;FBXL21;ortholog
2.56    FBXL5      NM_012161   F-box/LRR-repeat protein 5;FBXL5;ortholog
2.77    FBXW9      NM_032301   F-box/WD repeat-containing protein 9;FBXW9;ortholog
2.07    FCMD       NM_006731   Fukutin;FKTN;ortholog
2.71    FCRLA      NM_032738   Fc receptor-like A;FCRLA;ortholog receptor activity
-3.16   FEZF1      XM_371948                                     transcription factor
                               Fez family zinc finger protein 1;FEZF1;ortholog activity;transcription factor act
-2.28   FGF23      NM_020638                                     growth peptide;FGF23;ortholog
                               Fibroblast growth factor 23 C-terminal factor activity
2.32    FGF4       NM_002007                                     growth factor activity
                               Fibroblast growth factor 4;FGF4;ortholog
-2.59   FGFR1OP    NM_007045   FGFR1 oncogene partner;FGFR1OP;ortholog
2.27    FGFRL1     NM_021923                                     transmembrane receptor
                               Fibroblast growth factor receptor-like 1;FGFRL1;orthologprotein kinase activity;tr
3.08    FKHL18     NM_004118                                     transcription
                               Forkhead box protein S1;FOXS1;ortholog factor activity;transcription factor act
-2.35   FLJ13197   NM_024614   NM_024614.1 was permanently suppressed because currently there is support f
2.26    FLJ14959   XM_371139   This record was removed as a result of standard genome annotation processing
-2.65   FLJ22659   XM_378723   This record was removed as a result of standard genome annotation processing
-2.48   FLJ30435   XM_376845   NM_174950.2 was permanently suppressed because it is now thought that this g
-5.42   FLJ35785   NM_173613   This record was removed by RefSeq staff.
-2.38   FLJ45651   NM_198442   This record was removed by RefSeq staff.
-3.24   FLJ45684   NM_207462   NM_207462.1 was permanently suppressed because it is a nonsense-mediated
2.57    FLNB       NM_001457   Filamin-B;FLNB;ortholog           structural constituent of cytoskeleton;actin binding
2.36    FLRT2      NM_013231                                     receptor activity
                               Leucine-rich repeat transmembrane protein FLRT2;FLRT2;ortholog
2.21    FMO5       NM_001461                                     oxidoreductase activity
                               Dimethylaniline monooxygenase [N-oxide-forming] 5;FMO5;ortholog
-2.36   FNDC5      NM_153756 Fibronectin type III domain-containing protein 5;FNDC5;ortholog
2.15    FOXD4L2                                                transcription factor
                   NM_199135 Forkhead box protein D4-like 2;FOXD4L2;orthologactivity;transcription factor act
-2.86   FOXI2                                                  transcription factor activity;transcription factor act
                   NM_207426 Forkhead box protein I2;FOXI2;ortholog
2.33    FOXK2      NM_004514 Forkhead box protein K2;FOXK2;ortholog factor activity;transcription factor act
                                                               transcription
2.34    FOXN4      NM_213596 Forkhead box protein N4;FOXN4;ortholog factor activity;transcription factor act
                                                               transcription
3.51    FRMD8      NM_031904 FERM domain-containing protein 8;FRMD8;ortholog
2.27    FSIP2      NM_173651 Fibrous sheath-interacting protein 2;FSIP2;ortholog
2.40    FST        NM_013409 Follistatin;FST;ortholog          protein binding
-2.57   FTCD                                                   transferase activity;hydrolase
                   NM_006657 Formimidoyltetrahydrofolate cyclodeaminase;FTCD;ortholog activity;deaminase
-2.83   FTHFD                                                  oxidoreductase activity
                   NM_012190 10-formyltetrahydrofolate dehydrogenase;ALDH1L1;ortholog
-2.17   FUT5                                                   transferase activity, transferring glycosyl groups
                   NM_002034 Alpha-(1,3)-fucosyltransferase;FUT5;ortholog
4.07    FXYD2      NM_001680 Sodium/potassium-transporting ATPase gamma chain;FXYD2;ortholog
                                                               cation transmembrane transporter activity
2.12    FZR1       NM_016263 Fizzy-related protein homolog;FZR1;ortholog
                                                               protein binding
-2.35   GABARAP    NM_007278 Gamma-aminobutyric acid receptor-associated protein;GABARAP;ortholog
                                                               structural constituent of cytoskeleton;microtubule
2.20    GABPA      NM_002040 GA-binding protein alpha chain;GABPA;ortholog activity;transcription factor act
                                                               transcription factor
2.13    GABRG1     NM_173536 Gamma-aminobutyric acid receptor subunit gamma-1;GABRG1;ortholog
                                                               GABA receptor activity;ligand-gated ion channel a
-2.49   GAGE1      NM_001468 G antigen 1;GAGE1;ortholog
-2.08   GAGE2      NM_001472 G antigen 2A/2B;GAGE2B;ortholog
3.15    GALGT2     NM_153446 Beta-1,4 N-acetylgalactosaminyltransferase 2;B4GALNT2;ortholog
2.38    GALM       NM_138801 Aldose 1-epimerase;GALM;ortholog  racemase and epimerase activity
3.93    GAPDH      NM_002046 Glyceraldehyde-3-phosphate dehydrogenase;GAPDH;ortholog
                                                               oxidoreductase activity
-2.32   GAS1       NM_002048 Growth arrest-specific protein 1;GAS1;ortholog
-2.40   GATA5      NM_080473 Transcription factor GATA-5;GATA5;ortholog
                                                               nuclease activity;transcription factor activity;trans
2.18    GDF8       NM_005259 Growth/differentiation factor 8;MSTN;ortholog
                                                               growth factor activity
2.48    GDF9       NM_005260 Growth/differentiation factor 9;GDF9;ortholog
                                                               growth factor activity
2.09    GDNF       NM_000514 Glial cell line-derived neurotrophic factor;GDNF;ortholog
                                                               neurotrophin receptor binding;growth factor activi
2.57    GJB6       NM_006783 Gap junction beta-6 protein;GJB6;ortholog channel activity
                                                               gap junction
2.29    GNA11      NM_002067 Guanine nucleotide-binding protein subunit alpha-11;GNA11;ortholog
                                                               GTPase activity;protein binding
-2.07   GNB2                                                   GTPase activity;protein binding
                   NM_005273 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;GNB2;ortholog
-2.55   GNMT       NM_018960 Glycine N-methyltransferase;GNMT;ortholog
2.34    GNPDA2                                                 hydrolase activity;isomerase
                   NM_138335 Glucosamine-6-phosphate isomerase 2;GNPDA2;ortholog activity
-4.18   GPR114     NM_153837 Probable G-protein coupled receptor 114;GPR114;ortholog
                                                               G-protein coupled receptor activity
2.12    GPR137     NM_020155 Integral membrane protein GPR137;GPR137;ortholog
2.33    GPR137C    XM_290615 Integral membrane protein GPR137C;GPR137C;ortholog
2.53    GPR89B     NM_016334 Protein GPR89;GPR89B;ortholog
2.85    GPX6                                                   oxidoreductase activity;peroxidase activity
                   NM_182701 Glutathione peroxidase 6;GPX6;ortholog
-3.29   GRB10      NM_001001549Growth factor receptor-bound protein 10;GRB10;ortholog
3.61    GSG1       NM_031289 Germ cell-specific gene 1 protein;GSG1;ortholog
-2.91   GTF2A1     NM_015859 Transcription initiation factor IIA beta chain;GTF2A1;ortholog
                                                               transcription factor activity;transcription factor act
2.19    GTF2IRD1   NM_005685 General transcription factor II-I transcription factor activity;transcription factor act
                                                                repeat domain-containing protein 1;GTF2IRD1;o
-2.09   GYG2       NM_003918 Glycogenin-2;GYG2;ortholog transferase activity, transferring glycosyl groups
-3.62   H2BFA      NM_003518 Histone H2B type 1-C/E/F/G/I;HIST1H2BI;ortholog
2.04    HCLS1                                                  structural constituent of cytoskeleton;transcription
                   NM_005335 Hematopoietic lineage cell-specific protein;HCLS1;ortholog
2.73    HEATR7B2   NM_173489 HEAT repeat-containing protein 7B2;HEATR7B2;ortholog
-2.54   HECTD3     NM_024602 Probable E3 ubiquitin-protein ligase HECTD3;HECTD3;ortholog
                                                               ubiquitin-protein ligase activity
-3.05   HELIC1                                                  complex subunit 3;ASCC3;ortholog
                   NM_006828 Activating signal cointegrator 1 DNA helicase activity;RNA helicase activity;hydro
-2.84   HEPH       NM_014799 Hephaestin;HEPH;ortholog          oxidoreductase activity;serine-type peptidase acti
2.84    HERC3      NM_014606 Probable E3 ubiquitin-protein ligase HERC3;HERC3;ortholog
                                                               ubiquitin-protein ligase activity
-2.11   HHLA3      NM_007071 HERV-H LTR-associating protein 3;HHLA3;ortholog
-2.08   HINT1       NM_005340                                    nucleotide phosphatase activity;nucleotide phosp
                                Histidine triad nucleotide-binding protein 1;HINT1;ortholog
2.55    HINT3       NM_138571                                    damaged DNA binding
                                Histidine triad nucleotide-binding protein 3;HINT3;ortholog
2.35    HIST1H2BA   NM_170610   Histone H2B type 1-A;HIST1H2BA;ortholog
-3.41   HIST1H3B    NM_003537   Histone H3.1;HIST1H3J;ortholog
2.11    HLA-B       NM_005514   HLA class I histocompatibility antigen, B-8 alpha chain;HLA-B;ortholog
3.15    HLA-DRB1    NM_002124   HLA class II histocompatibility antigen, DRB1-1 beta chain;HLA-DRB1;ortholog
3.03    HMG4L       NM_178467   High mobility group protein B3-like;HMG4L;ortholog
-2.65   HMGB3       NM_005342   High mobility group protein B3;HMGB3;ortholog
-3.28   HOXA6       NM_024014                                    transcription
                                Homeobox protein Hox-A6;HOXA6;orthologfactor activity;transcription factor act
2.42    IDE         NM_004969                                    metallopeptidase activity
                                Insulin-degrading enzyme;IDE;ortholog
-2.79   IER5L       XM_372145   Immediate early response gene 5-like protein;IER5L;ortholog
2.92    IFI44       NM_006417   Interferon-induced protein 44;IFI44;ortholog
-2.21   IFNA13      NM_006900                                    hematopoietin/interferon-class (D200-domain) cy
                                Interferon alpha-1/13;IFNA13;ortholog
2.50    IGFBP3      NM_000598   Insulin-like growth factor-binding protein 3;IGFBP3;ortholog
-2.36   IHPK1       NM_153273                                    1;IHPK1;ortholog
                                Inositol hexaphosphate kinase kinase activity
2.61    IL1B        NM_000576   Interleukin-1 beta;IL1B;ortholog hematopoietin/interferon-class (D200-domain) cy
-2.60   IL1R2       NM_004633                                    cytokine receptor activity
                                Interleukin-1 receptor type II;IL1R2;ortholog
-2.25   IL1RL2      NM_003854                                    cytokine receptor activity
                                Interleukin-1 receptor-like 2;IL1RL2;ortholog
2.70    IL22RA2     NM_052962                                    alpha-2;IL22RA2;ortholog
                                Interleukin-22 receptor subunit cytokine receptor activity
2.51    IL28B       NM_172139   Interleukin-28B;IL28B;ortholog
2.78    IL4R        NM_000418                                    cytokine receptor activity
                                Soluble interleukin-4 receptor alpha chain;IL4R;ortholog
2.73    ILT7        NM_012276                                     receptor subfamily A member 4;LILRA4;ortholog
                                Leukocyte immunoglobulin-likereceptor activity
2.05    IMPDH2      NM_000884                                    oxidoreductase activity
                                Inosine-5'-monophosphate dehydrogenase 2;IMPDH2;ortholog
-2.31   INMT        NM_006774                                    methyltransferase activity
                                Indolethylamine N-methyltransferase;INMT;ortholog
2.03    INVS        NM_014425   Inversin;INVS;ortholog
2.61    IREM2       NM_181449                                    receptor activity
                                CMRF35-like molecule 2;CD300E;ortholog
2.23    IRS2        NM_003749   Insulin receptor substrate 2;IRS2;ortholog
2.86    JAGN1       NM_032492   Protein jagunal homolog 1;JAGN1;ortholog
-2.46   JMJD4       NM_023007                                    receptor activity
                                JmjC domain-containing protein 4;JMJD4;ortholog
-3.23   KCNJ12      NM_021012                                    voltage-gated potassium channel activity;voltage-
                                ATP-sensitive inward rectifier potassium channel 12;KCNJ12;ortholog
-2.15   KCNK16      NM_032115                                    voltage-gated potassium channel
                                Potassium channel subfamily K member 16;KCNK16;ortholog activity;voltage-
-2.16   KCTD17      NM_024681                                    voltage-gated potassium channel
                                BTB/POZ domain-containing protein KCTD17;KCTD17;ortholog activity;voltage-
2.24    KCTD2       NM_015353                                    voltage-gated potassium channel activity;voltage-
                                BTB/POZ domain-containing protein KCTD2;KCTD2;ortholog
2.02    KIAA0433    NM_015216   Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2;HI
-3.25   KIAA0649    NM_014811   Protein KIAA0649;KIAA0649;ortholog
-2.28   KIAA1009    XM_376518   Protein QN1 homolog;KIAA1009;ortholog
2.20    KIAA1033    NM_015275   UPF0681 protein KIAA1033;KIAA1033;ortholog
2.21    KIAA1049    NM_014972   Transcription factor 25;TCF25;ortholog
2.49    KIAA1191    NM_020444   UPF0498 protein KIAA1191;KIAA1191;ortholog
2.20    KIAA1229    XM_030665                                    extracellular matrix
                                Outer dense fiber protein 2-like;ODF2L;ortholog structural constituent
2.47    KIAA1285    NM_015694                                    transcription factor activity;transcription factor act
                                Zinc finger protein 777;ZNF777;ortholog
2.24    KIAA1340    XM_044836   Kelch domain-containing protein 5;KLHDC5;ortholog
2.66    KIAA1363    NM_020792                                     1;AADACL1;ortholog
                                Arylacetamide deacetylase-likelipase activity
-2.18   KIAA1443    NM_020834                                    transcription factor activity;transcription factor act
                                Homeobox and leucine zipper protein Homez;HOMEZ;ortholog
-2.39   KIAA1522    XM_036299   Uncharacterized protein KIAA1522;KIAA1522;ortholog
-2.32   KIAA1587    NM_020932   Melanoma-associated antigen E1;MAGEE1;ortholog
-2.27   KIAA1596    XM_048128   Fanconi anemia group M protein;FANCM;ortholog
-2.49   KIAA1698    NM_030628   Integrator complex subunit 5;INTS5;ortholog
2.90    KIF1B       NM_015074                                    microtubule
                                Kinesin-like protein KIF1B;KIF1B;ortholog motor activity;structural constituent o
-2.23   KIFC1       XM_371813, NM_002263 protein KIFC1;KIFC1;ortholog motor activity;structural constituent o
                                Kinesin-like                    microtubule
-3.06   KL          NM_153683 Klotho peptide;KL;ortholog        glucosidase activity;hydrolase activity, hydrolyzing
2.37    KLHDC6                                                  structural constituent
                    NM_207335 Kelch domain-containing protein 6;KLHDC6;orthologof cytoskeleton;actin binding
2.58    KLHL14      XM_035405 Kelch-like protein 14;KLHL14;ortholog
-2.47   KRT12       NM_000223 Keratin, type I cytoskeletal 12;KRT12;ortholog
                                                                structural constituent of cytoskeleton
-2.02   KRT5        NM_000424 Keratin, type II cytoskeletal 5;KRT5;ortholog
                                                                structural constituent of cytoskeleton
-2.92   LACRT       NM_033277 Extracellular glycoprotein lacritin;LACRT;ortholog
2.62    LANCL2      NM_018697 LanC-like protein 2;LANCL2;ortholog
2.00    LARP4       NM_052879 La-related protein 4;LARP4;ortholog
2.64    LARS2       NM_015340 Probable leucyl-tRNA synthetase, mitochondrial;LARS2;ortholog
                                                                aminoacyl-tRNA ligase activity
-2.39   LCK                                                     non-membrane spanning protein tyrosine kinase
                    NM_005356 Proto-oncogene tyrosine-protein kinase LCK;LCK;ortholog
-2.17   LCN15                                                   isomerase activity
                    NM_203347 Uncharacterized lipocalin UNQ2541/PRO6093;YA002_HUMAN;ortholog
-2.23   LEF1        NM_016269 Lymphoid enhancer-binding factor 1;LEF1;ortholog
                                                                nucleic acid binding
2.66    LILRB5      NM_006840 Leukocyte immunoglobulin-likereceptor activity
                                                                 receptor subfamily B member 5;LILRB5;ortholog
-1.99   LIMD2       NM_030576 LIM domain-containing protein structural constituent of cytoskeleton
                                                                2;LIMD2;ortholog
2.69    LIN7C       NM_018362 Lin-7 homolog C;LIN7C;ortholog
2.46    LINC00174   NM_181722 NM_181722.2: This RefSeq was permanently suppressed because currently the
2.61    LINC00346   NM_178514 NM_178514.3 was permanently suppressed because currently there is support f
-2.02   LMO4        NM_006769 LIM domain transcription factortranscription factor activity;transcription factor act
                                                                 LMO4;LMO4;ortholog
2.05    LMOD1       NM_012134 Leiomodin-1;LMOD1;ortholog structural constituent of cytoskeleton;actin binding
-2.89   LOC132870   XM_059608 This record was removed as a result of standard genome annotation processing
-2.13   LOC136143   XM_069734 This record was removed as a result of standard genome annotation processing
1.97    LOC144766   XM_378419 This record was removed as a result of standard genome annotation processing
-2.40   LOC147942   XM_085967 This record was removed as a result of standard genome annotation processing
2.63    LOC149934   XM_086725 NM_001039379.1 was permanently suppressed because it is now thought that t
-2.70   LOC163301   XM_088797 This record was removed as a result of standard genome annotation processing
-2.35   LOC196415   XM_378346 This record was removed as a result of standard genome annotation processing
-2.63   LOC200493   XM_115715 This record was removed as a result of standard genome annotation processing
-3.41   LOC254439   XM_170659 This record was removed as a result of standard genome annotation processing
2.41    LOC255189   XM_172929 This record was removed as a result of standard genome annotation processing
-2.42   LOC256374   XM_170597 This record was removed as a result of standard genome annotation processing
-2.31   LOC283065   XM_210876 This record was removed as a result of standard genome annotation processing
2.39    LOC283214   XM_378303 This record was removed as a result of standard genome annotation processing
2.69    LOC283332   XM_378355 This record was removed as a result of standard genome annotation processing
2.64    LOC283480   XM_378430 This record was removed as a result of standard genome annotation processing
2.21    LOC283483   XM_378431 This record was removed as a result of standard genome annotation processing
2.63    LOC284009   XM_378642 NM_001025459.2: This RefSeq was permanently suppressed because it is now
-3.04   LOC284385   XM_378777 This record was removed as a result of standard genome annotation processing
-2.60   LOC284912   XM_209413 NM_203375.1 was permanently suppressed because currently there is insufficie
-2.64   LOC285000   XM_379119 This record was removed as a result of standard genome annotation processing
3.38    LOC285189   XM_376111 This record was removed as a result of standard genome annotation processing
-3.03   LOC285647   XM_209700 This record was removed as a result of standard genome annotation processing
2.04    LOC285735   XM_379433 NM_001037231.1 was permanently suppressed because currently there is supp
2.00    LOC286094   XM_212170 This record was removed as a result of standard genome annotation processing
2.30    LOC286161   NM_181648 This record was removed by RefSeq staff; the sequence does not appear to rep
-2.05   LOC286453   XM_210054 This record was removed by RefSeq staff.
1.99    LOC286480   NM_207353 This record was removed by RefSeq staff; the sequence does not appear to rep
-2.22   LOC338758   XM_378371 This record was removed as a result of standard genome annotation processing
2.32    LOC338829   XM_292122 This record was removed as a result of standard genome annotation processing
-2.98   LOC340359   XM_294387   This record was removed as a result of standard genome annotation processing
-2.97   LOC342969   XM_292824   This record was removed as a result of standard genome annotation processing
-2.00   LOC343474   XM_291584   This record was removed as a result of standard genome annotation processing
-3.06   LOC345645   XM_293923   This record was removed as a result of standard genome annotation processing
-2.78   LOC345711   XM_293937   This record was removed as a result of standard genome annotation processing
-3.05   LOC387777   XM_373503   This record was removed as a result of standard genome annotation processing
-3.28   LOC387832   XM_370674   This record was removed as a result of standard genome annotation processing
2.36    LOC387888   XM_373550   This record was removed as a result of standard genome annotation processing
2.54    LOC387917   XM_373562   This record was removed as a result of standard genome annotation processing
2.20    LOC388123   XM_373628   This record was removed as a result of standard genome annotation processing
2.09    LOC388148   XM_370883   This record was removed as a result of standard genome annotation processing
-2.73   LOC388365   XM_373723   This record was removed as a result of standard genome annotation processing
-2.94   LOC388577   XM_373817   This record was removed as a result of standard genome annotation processing
-2.18   LOC388667   XM_373858   NM_001013643.1 was permanently suppressed because currently there is insuf
-2.41   LOC388752   XM_373894   This record was removed as a result of standard genome annotation processing
-2.99   LOC388965   XM_371504   NM_001013648.3 was permanently suppressed because it is now thought that t
2.25    LOC389143   XM_374047   This record was removed as a result of standard genome annotation processing
-3.69   LOC389270   XM_374112   This record was removed as a result of standard genome annotation processing
-2.35   LOC389490   XM_371901   This record was removed as a result of standard genome annotation processing
-3.11   LOC389659   XM_374270   This record was removed as a result of standard genome annotation processing
-3.41   LOC389660   XM_372042   This record was removed as a result of standard genome annotation processing
-2.66   LOC389753   XM_372112   This record was removed as a result of standard genome annotation processing
2.03    LOC389764   XM_372121   This record was removed as a result of standard genome annotation processing
1.98    LOC390680   XM_372611   This record was removed as a result of standard genome annotation processing
-3.73   LOC391767   XM_373078   uncharacterized LOC391767
-2.27   LOC391769   XM_373079   This record was removed as a result of standard genome annotation processing
2.19    LOC392222   XM_373253   This record was removed as a result of standard genome annotation processing
-2.95   LOC392790   XM_374751   This record was removed as a result of standard genome annotation processing
2.54    LOC399898   XM_374885   NM_001013666.1 was permanently suppressed because it is now thought that t
2.93    LOC400070   XM_378381   This record was removed as a result of standard genome annotation processing
-3.34   LOC400201   XM_378449   This record was removed as a result of standard genome annotation processing
-3.25   LOC400433   XM_378538   This record was removed as a result of standard genome annotation processing
-2.62   LOC400740   XM_378840   This record was removed as a result of standard genome annotation processing
-2.48   LOC400958   XM_379100   This record was removed as a result of standard genome annotation processing
2.14    LOC401081   XM_379206   This record was removed as a result of standard genome annotation processing
-2.06   LOC401264   XM_379417   This record was removed as a result of standard genome annotation processing
-2.73   LOC401328   XM_379485   This record was removed as a result of standard genome annotation processing
-2.21   LOC401399   XM_379517   This record was removed as a result of standard genome annotation processing
-3.76   LOC401497   XM_376822   This record was removed as a result of standard genome annotation processing
2.62    LOC401509   XM_376841   NM_001032297.1: This RefSeq was permanently suppressed because it is now
-2.82   LOC401528   XM_379642   This record was removed as a result of standard genome annotation processing
-2.35   LOC401529   XM_376872   This record was removed as a result of standard genome annotation processing
2.15    LOC401819   XM_377388   This record was removed as a result of standard genome annotation processing
-2.84   LOC402160   XM_377828   This record was removed as a result of standard genome annotation processing
-4.52   LOC402245   XM_377926   This record was removed as a result of standard genome annotation processing
-3.03   LOC402455   XM_374713   This record was removed as a result of standard genome annotation processing
2.61    LOC402509   XM_379840   This record was removed as a result of standard genome annotation processing
-3.03   LOC402578   XM_380135   This record was removed as a result of standard genome annotation processing
-2.57   LOC402681   XM_380025   This record was removed as a result of standard genome annotation processing
-2.55   LOC84856   NM_032770 NM_032770.3 was permanently suppressed because currently there is support f
-2.87   LOC91632   XM_039721 NM_001080422.1: This RefSeq was permanently suppressed because it is now
-2.79   LOC91948   XM_378549 This record was removed as a result of standard genome annotation processing
3.67    LOC93463   XM_376186 This record was removed as a result of standard genome annotation processing
-3.35   LOC96610   NM_080926 NM_080926.1 was permanently suppressed because currently there is support f
2.93    LRP12      NM_013437 Low-density lipoprotein receptor-related activity 12;LRP12;ortholog
                                                               receptor protein
-6.18   LTA        NM_000595 Lymphotoxin-alpha;LTA;ortholog    tumor necrosis factor receptor binding;cytokine a
-2.01   LU         NM_005581 Lutheran blood group glycoprotein;BCAM;ortholog
                                                               receptor activity
-2.28   MAGEA12    NM_005367 Melanoma-associated antigen 12;MAGEA12;ortholog
-2.06   MAP3K6                                                 protein kinase activity
                   NM_004672 Mitogen-activated protein kinase kinase kinase 6;MAP3K6;ortholog
-2.54   MAT2A                                                  nucleotidyltransferase activity
                   NM_005911 S-adenosylmethionine synthetase isoform type-2;MAT2A;ortholog
-3.00   MDK        NM_002391 Midkine;MDK;ortholog              cytokine activity
2.19    MDM4       NM_002393 Protein Mdm4;MDM4;ortholog ubiquitin-protein ligase activity
-2.58   MED9       NM_018019 Mediator of RNA polymerase II transcription subunit 9;MED9;ortholog
2.48    MFAP5      NM_003480 Microfibrillar-associated protein 5;MFAP5;ortholog
2.61    MGC23284   XM_378628 This record was removed as a result of standard genome annotation processing
-2.39   MGC9515    XM_375313 This record was removed as a result of standard genome annotation processing
-3.30   MLANA      NM_005511 Melanoma antigen recognized by T-cells 1;MLANA;ortholog
2.46    MLC1SA                                                 structural
                   NM_002475 Myosin light chain 6B;MYL6B;ortholog constituent of cytoskeleton;calcium ion
2.25    MLKL                                                   protein kinase activity
                   NM_152649 Mixed lineage kinase domain-like protein;MLKL;ortholog
-2.32   MLLT4      NM_005936 Afadin;MLLT4;ortholog             structural constituent of cytoskeleton;actin binding
2.52    MMP21      NM_147191 Matrix metalloproteinase-21;MMP21;ortholog
                                                               metallopeptidase activity
2.80    MPHOSPH1   NM_016195 M-phase phosphoprotein 1;MPHOSPH1;ortholog activity;structural constituent o
                                                               microtubule motor
1.99    MRPL32     NM_031903 39S ribosomal protein L32, mitochondrial;MRPL32;ortholog
                                                               structural constituent of ribosome;nucleic acid bin
-2.57   MRPL34     NM_023937 39S ribosomal protein L34, mitochondrial;MRPL34;ortholog
-2.23   MRPS12                                                 structural constituent of ribosome;nucleic acid bin
                   NM_021107 28S ribosomal protein S12, mitochondrial;MRPS12;ortholog
1.96    MRPS18A    NM_018135 28S ribosomal protein S18a, mitochondrial;MRPS18A;ortholog
                                                               structural constituent of ribosome;nucleic acid bin
-3.24   MRPS26     NM_030811 28S ribosomal protein S26, mitochondrial;MRPS26;ortholog
                                                               structural constituent of ribosome;nucleic acid bin
2.23    MRPS27     NM_015084 28S ribosomal protein S27, mitochondrial;MRPS27;ortholog
                                                               structural constituent of ribosome;nucleic acid bin
-2.94   MS4A1      NM_021950 B-lymphocyte antigen CD20;MS4A1;ortholog
                                                               receptor activity
-2.67   MTHFD2                                                 oxidoreductase activity;hydrolase activity;ligase a
                   NM_006636 Methenyltetrahydrofolate cyclohydrolase;MTHFD2;ortholog
-2.17   MTIF2                                                  hydrolase activity;translation factor activity, nuclei
                   NM_002453 Translation initiation factor IF-2, mitochondrial;MTIF2;ortholog
2.61    MTMR8      NM_017677 Myotubularin-related protein 8;MTMR8;ortholog
-2.45   MUC12      XM_379904 Mucin-12;MUC12;ortholog
-2.32   MVK        NM_000431 Mevalonate kinase;MVK;ortholog    kinase activity
2.27    MX2        NM_002463 Interferon-induced GTP-binding protein Mx2;MX2;ortholog
                                                               GTPase activity;structural constituent of cytoskele
2.32    MYCN       NM_006316 N-myc proto-oncogene protein;MYCN;ortholog
                                                               transcription factor activity;transcription factor act
2.13    MYEOV      NM_138768 Myeloma-overexpressed gene protein;MYEOV;ortholog
3.59    NARF       NM_012336 Nuclear prelamin A recognitionoxidoreductase activity
                                                                factor;NARF;ortholog
2.23    NAT8L      NM_178557 N-acetyltransferase 8-like protein;NAT8L;ortholog
2.18    NCOA5      NM_020967 Nuclear receptor coactivator 5;NCOA5;ortholog
                                                               receptor activity
2.95    NDEL1      NM_030808 Nuclear distribution protein nudE-like 1;NDEL1;ortholog
-2.34   NDFIP1     NM_030571 NEDD4 family-interacting protein 1;NDFIP1;ortholog
2.31    NEGR1      NM_173808 Neuronal growth regulator 1;NEGR1;ortholog
3.19    NEURL      NM_004210 Neuralized-like protein 1;NEURL;ortholog
                                                               ubiquitin-protein ligase activity
2.40    NFATC1     NM_006162 Nuclear factor of activated T-cells, cytoplasmic 1;NFATC1;ortholog
                                                               transcription factor activity;transcription factor act
-2.25   NFIC       NM_005597 Nuclear factor 1 C-type;NFIC;ortholog
                                                               transcription factor activity;transcription factor act
2.05    NICAL      NM_022765 NEDD9-interacting protein withstructural homology and cytoskeleton;actin binding
                                                                calponin constituent of LIM domains;MICAL1;or
2.44    NOMO3      NM_001004067Nodal modulator 3;NOMO3;ortholog
-3.67   NOXA1                                                 oxidoreductase
                   NM_006647 NADPH oxidase activator 1;NOXA1;ortholog activity
-2.79   NPIP       NM_006985 Nuclear pore complex-interacting protein;NPIP;ortholog
2.96    NR0B2      NM_021969 Nuclear receptor subfamily 0 group B member 2;NR0B2;ortholog activity;transcr
                                                              ligand-dependent nuclear receptor
2.09    NR2F6      NM_005234 Nuclear receptor subfamily 2 group F member 6;NR2F6;ortholog activity;transcr
                                                              ligand-dependent nuclear receptor
2.29    NRP2       NM_003872 Neuropilin-2;NRP2;ortholog oxidoreductase activity;serine-type peptidase acti
2.23    NSMAF      NM_003580 Protein FAN;NSMAF;ortholog protein binding
-3.42   NT5DC2     NM_022908 5'-nucleotidase domain-containing proteinphosphatase activity;nucleotide phosp
                                                              nucleotide 2;NT5DC2;ortholog
2.02    NT5M       NM_020201 5'(3')-deoxyribonucleotidase, mitochondrial;NT5M;ortholog
2.25    NUDT22     NM_032344 Nucleoside diphosphate-linked moiety X motif 22;NUDT22;ortholog
-2.08   NUDT5      NM_014142 ADP-sugar pyrophosphatase;NUDT5;ortholog activity
                                                              pyrophosphatase
-2.80   ODAG       NM_021167 GATA zinc finger domain-containing protein factor activity;transcription factor act
                                                              transcription 1;GATAD1;ortholog
2.64    OKL38      NM_013370 Oxidative stress-induced growth inhibitor 1;OSGIN1;ortholog
-2.36   OR10H5     XM_210787 Olfactory receptor 10H5;OR10H5;ortholog
2.17    OR2T11     NM_001001964Olfactory receptor 2T11;OR2T11;ortholog
2.44    OR4K17     XM_372504 Olfactory receptor 4K17;OR4K17;ortholog
2.14    OR5AP2     NM_001002925Olfactory receptor 5AP2;OR5AP2;ortholog
2.18    OR6B1      XM_069621 Olfactory receptor 6B1;OR6B1;ortholog
-2.95   OR8G2      XM_370662 Olfactory receptor 8G2;OR8G2;ortholog
2.08    OVCA2      NM_080822 Ovarian cancer-associated gene 2 protein;OVCA2;ortholog
                                                              transcription factor activity;transcription factor act
-2.58   OVTN       NM_198185 Ovochymase-2;OVCH2;ortholog      serine-type peptidase activity
2.53    PABPC1     NM_002568 Polyadenylate-binding protein 1;PABPC1;ortholog
                                                              RNA binding
-2.47   PACSIN2    NM_007229 Protein kinase C and casein kinase substrate in neurons protein 2;PACSIN2;orth
2.46    PAFAH1B1   NM_000430 Platelet-activating factor acetylhydrolase IB subunit alpha;PAFAH1B1;ortholog
                                                              hydrolase activity, acting on ester bonds
2.10    PAFAH2     NM_000437 Platelet-activating factor acetylhydrolase 2, cytoplasmic;PAFAH2;ortholog
                                                              hydrolase activity, acting on ester bonds
-2.63   PAIP2B     XM_376062 Polyadenylate-binding protein-interacting protein 2B;PAIP2B;ortholog
-1.96   PAK1IP1    NM_017906 p21-activated protein kinase-interacting protein 1;PAK1IP1;ortholog
                                                              protein binding;kinase inhibitor activity;kinase reg
-4.28   PARC       NM_015089 CCL18(4-69);CCL18;ortholog chemokine activity
2.35    PARP1      NM_001618 Poly [ADP-ribose] polymerase 1;PARP1;ortholog transferring glycosyl groups
                                                              transferase activity,
-2.46   PARP6      NM_020214 Poly [ADP-ribose] polymerase 6;PARP6;ortholog
2.28    PASD1                                                   1;PASD1;ortholog
                   NM_173493 PAS domain-containing proteintranscription factor activity;transcription factor act
2.22    PAX3       NM_000438 Paired box protein Pax-3;PAX3;ortholog
                                                              transcription factor activity;transcription factor act
2.48    PCDH8      NM_002590 Protocadherin-8;PCDH8;ortholog   calcium ion binding
-4.48   PCTK2                                                 protein kinase activity
                   NM_002595 Serine/threonine-protein kinase PCTAIRE-2;PCTK2;ortholog
2.01    PDCD2L     NM_032346 Programmed cell death proteintranscription factor activity;transcription factor act
                                                               2-like;PDCD2L;ortholog
2.46    PDGFRB                                                transmembrane receptor protein kinase activity;tr
                   NM_002609 Beta-type platelet-derived growth factor receptor;PDGFRB;ortholog
-3.13   PDLIM2     NM_021630 PDZ and LIM domain protein 2;PDLIM2;ortholog
                                                              structural constituent of cytoskeleton;actin binding
2.02    PDXDC2                                                carboxy-lyase activity
                   NM_199134 Pyridoxal-dependent decarboxylase domain-containing protein 2;PDXDC2;ortho
-2.05   PELP1      NM_014389 Proline-, glutamic acid- and leucine-rich protein 1;PELP1;ortholog
2.37    PENK       NM_006211 Met-enkephalin-Arg-Phe;PENK;ortholog
                                                              neuropeptide hormone activity
2.15    PEX10      NM_002617 Peroxisome assembly protein 10;PEX10;ortholog
2.31    PEX12      NM_000286 Peroxisome assembly protein 12;PEX12;ortholog
2.56    PFTK1                                                 protein kinase activity
                   NM_012395 Serine/threonine-protein kinase PFTAIRE-1;PFTK1;ortholog
-2.46   PGGT1B     NM_005023 Geranylgeranyl transferase type-1 subunit beta;PGGT1B;ortholog
                                                              acyltransferase activity
-2.18   PHF10      NM_018288 PHD finger protein 10;PHF10;ortholog
                                                              acetyltransferase activity;transcription factor activ
-2.25   PHLDA1     NM_007350 Pleckstrin homology-like domain family A member 1;PHLDA1;ortholog
-3.60   PI4KAP2                                               kinase alpha-like protein P2;PI4KAP2;ortholog
                   NM_199345 Putative phosphatidylinositol 4-kinase activity
-2.49   PIGM       NM_145167 GPI mannosyltransferase 1;PIGM;ortholog activity, transferring glycosyl groups
                                                              transferase
2.54    PKD2L1     NM_016112 Polycystic kidney disease 2-like 1 protein;PKD2L1;ortholog
                                                              ion channel activity
-4.38   PKIA                                                  protein binding;kinase inhibitor
                   NM_006823 cAMP-dependent protein kinase inhibitor alpha;PKIA;ortholog activity;kinase reg
-1.98   PLA2G3       NM_015715                                   phospholipase activity;calcium ion binding;calmod
                                 Group 3 secretory phospholipase A2;PLA2G3;ortholog
-2.00   PLAG1        NM_002655                                   transcription
                                 Zinc finger protein PLAG1;PLAG1;ortholog factor activity;transcription factor act
2.01    PLD4         NM_138790   Phospholipase D4;PLD4;ortholog  phospholipase activity
-2.35   PLEKHA1      NM_021622   Pleckstrin homology domain-containing family A member 1;PLEKHA1;ortholog
2.17    PLEKHO2      NM_025201   Pleckstrin homology domain-containing family O member 2;PLEKHO2;ortholog
2.52    PLSCR2       NM_020359   Phospholipid scramblase 2;PLSCR2;ortholog
2.46    PLXNC1       NM_005761   Plexin-C1;PLXNC1;ortholog transmembrane receptor protein kinase activity;tr
-2.89   PMCHL1       NM_031887                                   neuropeptide
                                 Pro-MCH-like protein 1;PMCHL1;ortholog hormone activity
-2.16   PML          NM_002675                                   ubiquitin-protein
                                 Probable transcription factor PML;PML;orthologligase activity
-2.72   PNKP         NM_007254                                   nucleotide kinase
                                 Polynucleotide 5'-hydroxyl-kinase;PNKP;ortholog activity;nucleotide phosphatase
-2.52   POLD4        NM_021173                                   4;POLD4;ortholog
                                 DNA polymerase delta subunit DNA-directed DNA polymerase activity;nucleotidy
-2.51   POLR2J       NM_006234                                     II subunit RPB11-a;POLR2J;ortholog
                                 DNA-directed RNA polymeraseDNA-directed RNA polymerase activity;nucleotidy
2.49    POPDC3       NM_022361   Popeye domain-containing protein 3;POPDC3;ortholog
2.70    POU2AF1      NM_006235   POU domain class 2-associating factor 1;POU2AF1;ortholog
2.90    POU5F2       NM_153216                                   transcription factor activity;transcription factor act
                                 POU domain, class 5, transcription factor 2;POU5F2;ortholog
2.33    PPBP         NM_002704                                   chemokine activity
                                 Neutrophil-activating peptide 2(1-63);PPBP;ortholog
-2.30   PPFIBP2      XM_084578   Liprin-beta-2;PPFIBP2;ortholog
-2.88   PPP1R3D      NM_006242                                   protein binding;phosphatase regulator activity
                                 Protein phosphatase 1 regulatory subunit 3D;PPP1R3D;ortholog
-2.73   PPP2R1A      NM_014225                                   phosphoprotein phosphatase activity;phosphopro
                                 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isof
-2.03   PRAMEF8      XM_372762   PRAME family member 8;PRAMEF8;ortholog
1.98    PREI3        NM_015387                                   protein binding;kinase activator activity;kinase reg
                                 Mps one binder kinase activator-like 3;MOBKL3;ortholog
-2.27   PRKCB        NM_002738                                   protein kinase
                                 Protein kinase C beta type;PRKCB;ortholog activity;calcium ion binding;calmod
2.36    PRR16        NM_016644   Proline-rich protein 16;PRR16;ortholog
2.15    PRR7         NM_030567   Proline-rich protein 7;PRR7;ortholog
-3.37   PSAP         NM_002778   Saposin-D;PSAP;ortholog         protein binding;enzyme regulator activity
2.09    PTCH2        NM_003738                                   receptor activity
                                 Protein patched homolog 2;PTCH2;ortholog
2.16    PTCRA        NM_138296   Pre T-cell antigen receptor alpha;PTCRA;ortholog
2.93    PTPN12       NM_002835                                   phosphoprotein phosphatase activity;phosphopro
                                 Tyrosine-protein phosphatase non-receptor type 12;PTPN12;ortholog
2.69    PTPN22       NM_012411                                   phosphoprotein phosphatase activity;phosphopro
                                 Tyrosine-protein phosphatase non-receptor type 22;PTPN22;ortholog
2.55    PTPN23       NM_015466                                   phosphoprotein phosphatase activity;phosphopro
                                 Tyrosine-protein phosphatase non-receptor type 23;PTPN23;ortholog
2.35    PTPRU        NM_005704                                   phosphatase U;PTPRU;ortholog
                                 Receptor-type tyrosine-protein phosphoprotein phosphatase activity;phosphopro
2.45    QSCN6        NM_002826                                   oxidoreductase activity;protein disulfide isomeras
                                 Sulfhydryl oxidase 1;QSOX1;ortholog
-3.74   RAB11-FIP2   NM_014904   Rab11 family-interacting protein 2;RAB11FIP2;ortholog
2.33    RAB11B       NM_004218                                   GTPase activity;protein binding
                                 Ras-related protein Rab-11B;RAB11B;ortholog
-3.02   RAB40C       NM_021168                                   GTPase activity;protein binding
                                 Ras-related protein Rab-40C;RAB40C;ortholog
2.87    RAB7         NM_004637                                   GTPase activity;protein binding
                                 Ras-related protein Rab-7a;RAB7A;ortholog
-2.64   RAG1         NM_000448                                     protein 1;RAG1;ortholog
                                 V(D)J recombination-activatingendodeoxyribonuclease activity;nucleic acid bindi
2.86    RAG1AP1      NM_018845   RAG1-activating protein 1;RAG1AP1;ortholog
-3.45   RAI16        NM_022749   UPF0518 protein FAM160B2;FAM160B2;ortholog
-2.31   RANBP3L      NM_145000                                   protein binding;small GTPase regulator activity
                                 Ran-binding protein 3-like;RANBP3L;ortholog
2.51    RASA1        NM_002890                                    1;RASA1;ortholog
                                 Ras GTPase-activating protein protein binding;small GTPase regulator activity
2.84    RCAN1        NM_004414   Calcipressin-1;RCAN1;ortholog   receptor binding
2.58    RFXANK       NM_003721                                   transcription factor
                                 DNA-binding protein RFXANK;RFXANK;ortholog activity;transcription factor act
2.60    RFXAP        NM_000538   Regulatory factor X-associated protein;RFXAP;ortholog
-2.72   RHBDF1       NM_022450                                   serine-type peptidase activity
                                 Rhomboid family member 1;RHBDF1;ortholog
-3.63   RING1        NM_002931                                   transcription factor
                                 E3 ubiquitin-protein ligase RING1;RING1;ortholog activity;transcription factor act
2.89    RIPX         NM_014961                                   t
                                 Protein RUFY3;RUFY3;orthologranscription factor activity;transcription factor act
2.04    RLN1         NM_006911   Relaxin A chain;RLN1;orthologhormone activity
-6.09   RNF14        NM_004290                                   ubiquitin-protein ligase activity;transcription factor
                                 E3 ubiquitin-protein ligase RNF14;RNF14;ortholog
2.24                NM_016422
        RNF141,ZNF230           RING finger protein 141;RNF141;ortholog
-2.26   RNF34       NM_025126                                      ubiquitin-protein ligase activity
                                E3 ubiquitin-protein ligase RNF34;RNF34;ortholog
-4.24   RNF38       NM_022781   RING finger protein 38;RNF38;ortholog
-3.29   RNF44       NM_014901   RING finger protein 44;RNF44;ortholog
2.25    RNGTT       NM_003800                                      nucleotidyltransferase activity
                                mRNA guanylyltransferase;RNGTT;ortholog
-2.79   RPL13AP17 NM_203308     ribosomal protein L13a pseudogene 17
2.69    RPS15       XM_376154                                      structural constituent of ribosome;nucleic acid bin
                                40S ribosomal protein S15;RPS15;ortholog
-2.03   RSC1A1      NM_006511                                      carbohydrate transmembrane transporter
                                Regulatory solute carrier protein family 1 member 1;RSC1A1;ortholog activity
-2.69   RTN4RL1     NM_178568                                      receptor activity
                                Reticulon-4 receptor-like 1;RTN4RL1;ortholog
-2.71   RWDD2       NM_033411   RWD domain-containing protein 2A;RWDD2A;ortholog
2.27    RYR1        NM_000540                                      receptor
                                Ryanodine receptor 1;RYR1;ortholog activity;ligand-gated ion channel activity
2.37    SALL3       NM_171999   Sal-like protein 3;SALL3;ortholog  transcription factor activity;transcription factor act
2.39    SARM1       NM_015077                                      protein protein
                                Sterile alpha and TIR motif-containing binding 1;SARM1;ortholog
-2.14   SATB1       NM_002971                                      transcription factor activity;transcription factor act
                                DNA-binding protein SATB1;SATB1;ortholog
2.93    SBF2        NM_030962   Myotubularin-related protein 13;SBF2;ortholog
2.22    SCARB1      NM_005505                                      receptor activity
                                Scavenger receptor class B member 1;SCARB1;ortholog
-3.68   SCRG1       NM_007281   Scrapie-responsive protein 1;SCRG1;ortholog
2.25    SCYE1       NM_004757                                      aminoacyl-tRNA ligase activity
                                Endothelial monocyte-activating polypeptide 2;SCYE1;ortholog
2.60    SDSL        NM_138432                                      hydrolase
                                Serine dehydratase-like;SDSL;ortholog activity;hydro-lyase activity;racemase a
2.62    SEC14L1     NM_003003   SEC14-like protein 1;SEC14L1;ortholog
-1.98   SEC22L3     NM_004206                                      SNAP receptor activity
                                Vesicle-trafficking protein SEC22c;SEC22C;ortholog
-2.24   SEC23IP     NM_007190                                      phospholipase
                                SEC23-interacting protein;SEC23IP;ortholog activity
2.14    SELH        NM_170746   Selenoprotein H;SELH;ortholog
2.35    SELM        NM_080430   Selenoprotein M;SELM;ortholog
-3.52   SERPINB10 NM_005024     Serpin B10;SERPINB10;ortholog      protein binding;serine-type endopeptidase inhibito
2.32    SERPINB4    NM_002974   Serpin B4;SERPINB4;ortholog protein binding;serine-type endopeptidase inhibito
-2.18   SFRS2       NM_003016                                      RNA splicing factor activity, transesterification me
                                Splicing factor, arginine/serine-rich 2;SFRS2;ortholog
2.00    SFRS2IP     NM_004719   SFRS2-interacting protein;SFRS2IP;ortholog
2.49    SGEF        NM_015595   SH3 domain-containing guanine exchange factor;SGEF;ortholog
2.27    SH2D6       NM_198482                                       6;SH2D6;ortholog
                                SH2 domain-containing proteinreceptor binding
2.18    SH3MD1      XM_374831   SH3 and PX domain-containing protein 2A;SH3PXD2A;ortholog
-3.91   SHARPIN     NM_030974   Sharpin;SHARPIN;ortholog           ubiquitin-protein ligase activity
2.90    SHB         NM_003028   SH2 domain-containing adapter protein B;SHB;ortholog
2.21    SHPRH       NM_173082                                      DNA helicase activity;nucleic acid binding
                                E3 ubiquitin-protein ligase SHPRH;SHPRH;ortholog
-2.60   SIAT7E      NM_030965                                       alpha-2,6-sialyltransferase 5;ST6GALNAC5;orth
                                Alpha-N-acetylgalactosaminidetransferase activity, transferring glycosyl groups
-4.00   SIGIRR      NM_021805                                      cytokine receptor
                                Single Ig IL-1-related receptor;SIGIRR;ortholog activity
-3.14   SIPA1       NM_006747                                      protein binding;small GTPase regulator activity
                                Signal-induced proliferation-associated protein 1;SIPA1;ortholog
2.44    SIRPA       NM_080792                                      chemokine activity
                                Tyrosine-protein phosphatase non-receptor type substrate 1;SIRPA;ortholog
2.12    SIRT3       NM_012239                                      deacetylase activity;nucleic acid binding;chromati
                                NAD-dependent deacetylase sirtuin-3, mitochondrial;SIRT3;ortholog
2.65    SLA         NM_006748   SRC-like-adapter;SLA;orthologreceptor binding
-2.29   SLA2        NM_032214   Src-like-adapter 2;SLA2;ortholog   receptor binding
-2.50   SLC12A7     NM_006598                                      cation transmembrane
                                Solute carrier family 12 member 7;SLC12A7;ortholog transporter activity
-2.64   SLC25A26    NM_173471   S-adenosylmethionine mitochondrial carrier protein;SLC25A26;ortholog
2.18    SLC2A2      NM_000340                                      carbohydrate transmembrane 2;SLC2A2;ortholo
                                Solute carrier family 2, facilitated glucose transporter membertransporter activity
2.39    SLC39A4     NM_017767                                      transmembrane transporter activity
                                Zinc transporter ZIP4;SLC39A4;ortholog
3.32    SLC6A15     NM_018057                                      cation transmembrane transporter activity
                                Orphan sodium- and chloride-dependent neurotransmitter transporter NTT73;SL
-2.39   SLFN12      NM_018042   Schlafen family member 12;SLFN12;ortholog
3.06    SLITRK4     NM_173078                                      receptor activity
                                SLIT and NTRK-like protein 4;SLITRK4;ortholog
2.09    SMAD6       NM_005585                                      transcription factor activity;transcription factor act
                                Mothers against decapentaplegic homolog 6;SMAD6;ortholog
2.55    SMAP-1     NM_018671   Protein unc-45 homolog A;UNC45A;ortholog
-2.29   SMAP2      NM_022733                                      protein 2;SMAP2;ortholog
                               Stromal membrane-associatednucleic acid binding;protein binding;small GTPas
2.26    SMPX       NM_014332   Small muscular protein;SMPX;ortholog
-2.72   SNX16      NM_022133   Sorting nexin-16;SNX16;ortholog   kinase activity
-2.42   SOM        NM_021180                                     transcription factor activity;transcription factor act
                               Grainyhead-like protein 3 homolog;GRHL3;ortholog
2.77    SORL1      NM_003105                                     receptor activity;transmembrane transporter activ
                               Sortilin-related receptor;SORL1;ortholog
2.60    SOX10      NM_006941                                     transcription factor activity;transcription factor act
                               Transcription factor SOX-10;SOX10;ortholog
2.61    SOX9       NM_000346                                     transcription
                               Transcription factor SOX-9;SOX9;ortholog factor activity;transcription factor act
3.85    SP1        NM_138473                                     transcription factor activity;transcription factor act
                               Transcription factor Sp1;SP1;ortholog
2.28    SP4        NM_003112                                     transcription factor activity;transcription factor act
                               Transcription factor Sp4;SP4;ortholog
2.18    SPAG6      NM_012443                                     structural constituent of cytoskeleton
                               Sperm-associated antigen 6;SPAG6;ortholog
2.44    SPATA24    XM_114430   Spermatogenesis-associated protein 24;SPATA24;ortholog
-2.17   SPIN3      XM_093024   Spindlin-3;SPIN3;ortholog
-2.97   SR-A1      NM_021228   Splicing factor, arginine/serine-rich 19;SCAF1;ortholog
-2.43   SRR        NM_021947   Serine racemase;SRR;orthologhydrolase activity;hydro-lyase activity;racemase a
2.24    STK10      NM_005990                                     protein kinase activity
                               Serine/threonine-protein kinase 10;STK10;ortholog
2.24    STK11      NM_000455                                     protein kinase activity
                               Serine/threonine-protein kinase 11;STK11;ortholog
2.22    STK11IP    NM_052902   Serine/threonine kinase 11-interacting protein;STK11IP;ortholog
-2.89   SUPT3H     NM_003599                                     transcription factor activity;transcription factor act
                               Transcription initiation protein SPT3 homolog;SUPT3H;ortholog
2.37    SVEP1      AK023591    Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing prote
2.98    TCIRG1     NM_006019                                       subunit a isoform 3;TCIRG1;ortholog
                               V-type proton ATPase 116 kDacation transmembrane transporter activity;hydrog
2.47    TCN2       NM_000355   Transcobalamin-2;TCN2;ortholog    cation transmembrane transporter activity
2.51    TENR       NM_139243                                     hydrolase protein 1;ADAD1;ortholog
                               Adenosine deaminase domain-containingactivity;deaminase activity;DNA binding
2.65    TFCP2      NM_005653                                     transcription factor activity;transcription factor act
                               Alpha-globin transcription factor CP2;TFCP2;ortholog
2.66    TGFB1      NM_000660                                     growth factor
                               Latency-associated peptide;TGFB1;ortholog activity
2.56    THEX1      NM_153332                                      1;THEX1;ortholog
                               Histone mRNA 3'-exonuclease exoribonuclease activity;nucleic acid binding
-2.34   THRAP4     NM_014815                                      transcription subunit 24;MED24;ortholog
                               Mediator of RNA polymerase IIreceptor activity
-3.00   TIF1       NM_003852                                     ubiquitin-protein ligase activity;transcription factor
                               Transcription intermediary factor 1-alpha;TRIM24;ortholog
2.17    TIMM10     NM_012456   Mitochondrial import inner membrane translocase subunit Tim10;TIMM10;orthol
2.44    TIMM13     NM_012458   Mitochondrial import inner membrane translocase subunit Tim13;TIMM13;orthol
3.06    TIMM8B     NM_012459                                     cation translocase subunit Tim8 B;TIMM8B;ortho
                               Mitochondrial import inner membranetransmembrane transporter activity
2.66    TKTL2      NM_032136                                     transketolase
                               Transketolase-like protein 2;TKTL2;ortholog activity
2.45    TLK2       NM_006852                                     protein kinase activity
                               Serine/threonine-protein kinase tousled-like 2;TLK2;ortholog
2.03    TLR9       NM_017442   Toll-like receptor 9;TLR9;orthologreceptor activity
2.41    TM4SF18    NM_138786   Transmembrane 4 L6 family member 18;TM4SF18;ortholog
-2.36   TMCC2      NM_014858   Transmembrane and coiled-coil domains protein 2;TMCC2;ortholog
-2.68   TMEM106A   NM_145041   Transmembrane protein 106A;TMEM106A;ortholog
2.37    TMEM139    NM_153345   Transmembrane protein 139;TMEM139;ortholog
2.26    TMEM140    NM_018295   Transmembrane protein 140;TMEM140;ortholog
2.80    TMEM14B    NM_030969   Transmembrane protein 14B;TMEM14B;ortholog
2.47    TMEM150    NM_153342   Transmembrane protein 150;TMEM150;ortholog
2.52    TMEM16D    NM_178826   Anoctamin-4;ANO4;ortholog
2.26    TMEM179B   NM_199337   Transmembrane protein 179B;TMEM179B;ortholog
2.54    TMEM203    NM_053045   Transmembrane protein 203;TMEM203;ortholog
3.47    TMEM69     NM_016486   Transmembrane protein 69;TMEM69;ortholog
2.59    TMF1       NM_007114   TATA element modulatory factor;TMF1;ortholog
2.28    TNFRSF8    NM_001243                                      superfamily member 8;TNFRSF8;ortholog
                               Tumor necrosis factor receptorreceptor activity
2.98    TNNC1      NM_003280                                     structural constituent of cytoskeleton;calcium ion
                               Troponin C, slow skeletal and cardiac muscles;TNNC1;ortholog
-3.14   TNNI2      NM_003282                                     structural constituent of cytoskeleton;actin binding
                               Troponin I, fast skeletal muscle;TNNI2;ortholog
2.82    TNPO2       NM_013433   Transportin-2;TNPO2;ortholog transmembrane transporter activity
3.15    TNRC11      NM_005120                                     transcription subunit 12;MED12;ortholog
                                Mediator of RNA polymerase IItranscription factor activity;transcription factor act
2.64    TNT         NM_182831                                    motor activity;structural constituent of cytoskeleto
                                Troponin T, slow skeletal muscle;TNNT1;ortholog
-3.59   TOMM34      NM_006809   Mitochondrial import receptor subunit TOM34;TOMM34;ortholog
-3.31   TOX         XM_376776                                    transcription factor activity;chromatin binding;tran
                                Thymocyte selection-associated high mobility group box protein TOX;TOX;ortho
2.64    TP53BP1     NM_005657                                     protein 1;TP53BP1;ortholog
                                Tumor suppressor p53-bindingtranscription factor activity;transcription factor act
2.09    TP73        NM_005427   Tumor protein p73;TP73;ortholog  transcription factor activity;transcription factor act
-2.82   TRAF2       NM_021138                                      2;TRAF2;ortholog
                                TNF receptor-associated factorreceptor binding
2.41    TRAPPC3     NM_014408   Trafficking protein particle complex subunit 3;TRAPPC3;ortholog
-2.62   TRIM25      NM_005082                                    ubiquitin-protein ligase
                                Tripartite motif-containing protein 25;TRIM25;ortholog activity
-2.70   TRIM28      NM_003449                                    ubiquitin-protein ligase activity;transcription factor
                                Transcription intermediary factor 1-beta;TRIM28;ortholog
-2.92   TRIM28      NM_005762                                    ubiquitin-protein ligase activity;transcription factor
                                Transcription intermediary factor 1-beta;TRIM28;ortholog
2.41    TRIM52      NM_032765                                    ubiquitin-protein ligase
                                Tripartite motif-containing protein 52;TRIM52;ortholog activity
2.32    TRPC3       NM_003305                                    ion channel activity
                                Short transient receptor potential channel 3;TRPC3;ortholog
-2.05   TSCOT       NM_033051   Thymic stromal cotransporter homolog;SLC46A2;ortholog
-2.33   TTC1        NM_003314   Tetratricopeptide repeat protein 1;TTC1;ortholog
-2.99   TTC30B      NM_152517   Tetratricopeptide repeat protein 30B;TTC30B;ortholog
3.50    TTLL6       NM_173623                                    ligase activity;structural constituent of cytoskeleto
                                Tubulin polyglutamylase TTLL6;TTLL6;ortholog
-2.10   TUBA3E      NM_207312                                    structural constituent of cytoskeleton
                                Tubulin alpha-3E chain;TUBA3E;ortholog
2.20    TXK         NM_003328                                    non-membrane spanning protein tyrosine kinase
                                Tyrosine-protein kinase TXK;TXK;ortholog
-3.60   UBCE7IP5    NM_014948   RING finger protein 37;UBOX5;ortholog
3.39    UBE2J1      NM_016021                                    ligase activity
                                Ubiquitin-conjugating enzyme E2 J1;UBE2J1;ortholog
-2.47   UBE2J2      NM_058167                                    ubiquitin-protein ligase
                                Ubiquitin-conjugating enzyme E2 J2;UBE2J2;ortholog activity
2.08    UBXN2B      XM_059929   UBX domain-containing protein 2B;UBXN2B;ortholog
-2.80   UHRF1       NM_013282                                    transcription factor activity;transcription factor act
                                E3 ubiquitin-protein ligase UHRF1;UHRF1;ortholog
3.34    UIMC1       NM_016290   Ubiquitin interaction motif-containing protein 1;UIMC1;ortholog
-2.28   UNQ9373     NM_207314   This record was removed by RefSeq staff; the sequence does not appear to rep
-3.14   UPK1A       NM_007000   Uroplakin-1a;UPK1A;ortholog
-6.64   USP10       NM_005153                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 10;USP10;ortholog
-2.84   USP13       NM_003940                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 13;USP13;ortholog
-2.99   USP20       NM_006676                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 20;USP20;ortholog
-3.64   USP24       XM_165973                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 24;USP24;ortholog
-4.99   USP46       NM_022832                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 46;USP46;ortholog
2.32    USP5        NM_003481                                    cysteine-type peptidase
                                Ubiquitin carboxyl-terminal hydrolase 5;USP5;ortholog activity
2.42    USP51       NM_201286                                    cysteine-type peptidase activity
                                Ubiquitin carboxyl-terminal hydrolase 51;USP51;ortholog
-2.93   USP9Y,USP10 NM_004654                                    cysteine-type peptidase activity
                                Probable ubiquitin carboxyl-terminal hydrolase FAF-Y;USP9Y;ortholog
-2.32   VENTX2      NM_014468                                    transcription
                                Homeobox protein VENTX;VENTX;ortholog factor activity;transcription factor act
3.73    VPS16       NM_022575   Vacuolar protein sorting-associated protein 16 homolog;VPS16;ortholog
2.22    VSTM2A      NM_182546   V-set and transmembrane domain-containing protein 2A;VSTM2A;ortholog
-2.66   VSTM2B      XM_292785                                    receptor activity
                                V-set and transmembrane domain-containing protein 2B;VSTM2B;ortholog
2.42    WBSCR16     NM_030798                                    protein binding;small GTPase regulator activity;gu
                                Williams-Beuren syndrome chromosomal region 16 protein;WBSCR16;ortholog
2.43    WBSCR28     NM_182504   Williams-Beuren syndrome chromosomal region 28 protein;WBSCR28;ortholog
2.84    WDFY3       NM_014991                                    protein binding
                                WD repeat and FYVE domain-containing protein 3;WDFY3;ortholog
2.67    WDR87       XM_371164   WD repeat-containing protein 87;WDR87;ortholog
2.49    WDR88       NM_173479   WD repeat-containing protein 88;WDR88;ortholog
2.19    WISP1       NM_003882                                    growth factor activity
                                WNT1-inducible-signaling pathway protein 1;WISP1;ortholog
3.30    WNT16       NM_016087   Protein Wnt-16;WNT16;ortholog    receptor binding
2.10    WNT2B       NM_004185   Protein Wnt-2b;WNT2B;ortholog    receptor binding
3.10    WSB1        NM_134264   WD repeat and SOCS box-containing protein 1;WSB1;ortholog
-3.08   WWP1      NM_007013                                 ubiquitin-protein ligase activity
                              NEDD4-like E3 ubiquitin-protein ligase WWP1;WWP1;ortholog
2.40    YIPF6     NM_173834   Protein YIPF6;YIPF6;ortholog
-2.10   ZC3H12D   XM_291154                                 nucleic acid binding
                              Zinc finger CCCH domain-containing protein 12D;ZC3H12D;ortholog
2.31    ZDHHC4    NM_018106   Probable palmitoyltransferase ZDHHC4;ZDHHC4;ortholog
-3.29   ZFX       NM_003410                                 transcription factor
                              Zinc finger X-chromosomal protein;ZFX;ortholog activity;transcription factor act
-2.91   ZMYND11   NM_006624                                 transcription factor activity;transcription
                              Zinc finger MYND domain-containing protein 11;ZMYND11;ortholog factor act
-2.85   ZNF140    NM_003440                                 transcription factor activity;transcription factor act
                              Zinc finger protein 140;ZNF140;ortholog
3.29    ZNF187    NM_152736                                 transcription factor activity;transcription factor act
                              Zinc finger protein 187;ZNF187;ortholog
2.57    ZNF24     NM_006965                                 transcription factor activity;transcription factor act
                              Zinc finger protein 24;ZNF24;ortholog
-2.33   ZNF266    NM_006631                                 transcription factor activity;transcription factor act
                              Zinc finger protein 266;ZNF266;ortholog
1.97    ZNF281    NM_012482                                 transcription factor activity;transcription factor act
                              Zinc finger protein 281;ZNF281;ortholog
2.41    ZNF354C   NM_014594                                 transcription
                              Zinc finger protein 354C;ZNF354C;ortholog factor activity;transcription factor act
-2.45   ZNF426    NM_024106                                 transcription factor activity;transcription factor act
                              Zinc finger protein 426;ZNF426;ortholog
-2.15   ZNF543    NM_213598                                 transcription factor activity;transcription factor act
                              Zinc finger protein 543;ZNF543;ortholog
2.91    ZNF673    NM_017776   Protein ZNF673;ZNF673;orthologtranscription factor activity;transcription factor act
-2.58   ZNF750    NM_024702   Protein ZNF750;ZNF750;ortholog
-2.36   ZNF837    XM_375665                                 transcription factor activity;transcription factor act
                              Zinc finger protein 837;ZNF837;ortholog
1.96    ZPLD1     NM_175056   Zona pellucida-like domain-containing protein 1;ZPLD1;ortholog
-4.21   ZSWIM5    XM_046581   Zinc finger SWIM domain-containing protein 5;ZSWIM5;ortholog
             GO Biological Process             GO Cellular Component         Panther Protein Class
                                                                             cytokine;serine protease inhibitor
             immune system process;signal transduction;cell-cell signaling;proteolysis;signal transduction;cell-cell signaling
             fatty acid metabolic process                                    ligase
             immune system process;extracellular transport;response to toxin ATP-binding cassette (ABC) transporter
             immune system process;extracellular transport;response to toxin ATP-binding cassette (ABC) transporter
                                                                             ATP-binding cassette (ABC) transporter
             immune system process;extracellular transport;carbohydrate metabolic process;response to toxin
             lipid transport;lipid metabolic process                         transporter
             lipid transport;lipid metabolic process                         transporter
                                                                             transferase;dehydrogenase
             respiratory electron transport chain;acyl-CoA metabolic process;acyl-CoA metabolic process
             proteolysis                                                     metalloprotease;metalloprotease
             fatty acid beta-oxidation                                       oxidase
                                                                             protein phosphatase;protein phosphatase
             transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
             fatty acid metabolic process                                    ligase
                                                                             serine/threonine protein kinase receptor;TGF-beta receptor;serin
             cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protein amino
                                                                             serine/threonine protein kinase receptor;TGF-beta receptor;serin
             cytokine-mediated signaling pathway;transmembrane receptor protein serine/threonine kinase signaling pathway;protein amino
                                                                             metalloprotease;metalloprotease
             signal transduction;cell-cell adhesion;proteolysis;signal transduction;cell-cell adhesion
             cellular amino acid biosynthetic process                        decarboxylase
             cyclic nucleotide metabolic process                             adenylate cyclase
                                                                             ligase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

              regulation of transcription from RNA polymerase II promoter transcription cofactor
              transport                                                      transfer/carrier protein
              transport;mesoderm development                                 transfer/carrier protein
                                                                             reductase
              immune system process;respiratory electron transport chain;ferredoxin metabolic process;oxygen and reactive oxygen species
              protein targeting;signal transduction;signal transduction      signaling molecule
                                                                             kinase activator
              protein targeting;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
              metabolic process                                              dehydrogenase
              immune system process;lipid metabolic process                  oxygenase
              phosphate metabolic process;protein amino acid phosphorylation protein kinase;protein kinase
 gy protein 1;AMBRA1;ortholog
              proteolysis
              glycogen metabolic process                                     amylase
                                                                             signaling molecule;kinase modulator
              transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein tyrosine kinase signaling p
              mesoderm development;angiogenesis                              signaling molecule
KRD43;ortholog
 osphatase inhibitor activity;phosphatase regulator activity                 phosphatase inhibitor
              intracellular protein transport;pinocytosis                    membrane traffic protein
              lipid transport;lipid metabolic process                        transporter;apolipoprotein
              blood circulation;lipid transport;lipid metabolic process      transporter;apolipoprotein
              lipid transport;cholesterol metabolic process                  transporter;apolipoprotein
                                                                             nucleic acid binding;G-protein modulator
              G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad
              transport                                                      transporter

                                                                              growth factor
            signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
            proteolysis                                                       cysteine protease;cysteine protease
 GEF17;ortholog
                                                                              guanyl-nucleotide exchange factor
            neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling
                                                                              chromatin/chromatin-binding protein
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin architecture
RMCX3;ortholog
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                             enzyme modulator
             visual perception;sensory perception;intracellular protein transport;endocytosis;G-protein coupled receptor protein signaling pat

                                                                         hydrolase
             sulfur metabolic process;polysaccharide metabolic process;phospholipid metabolic process


                                                                               receptor;defense/immunity protein;cell adhesion molecule
             macrophage activation;intracellular protein transport;receptor-mediated endocytosis;signal transduction;cell-cell adhesion;signa
                                                                               signaling molecule
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
actor ATF-6 beta;ATF6B;ortholog

                                             proton-transporting ATP nucleic acid metabolic process
                                                                          ATP synthase;hydrolase
             cation transport;nucleobase, nucleoside, nucleotide andsynthase complex
             cation transport                                             ATP synthase
             cation transport                                             ATP synthase;nucleotide phosphatase;nucleotide phosphatase
             cation transport;purine base metabolic process               ATP synthase;hydrolase
             immune system process;mesoderm development;mammary gland development;cellular defense response
             signal transduction;signal transduction                      receptor

                                                                              transcription cofactor
             cell surface receptor linked signal transduction;transcription from RNA polymerase II promoter;cell surface receptor linked signa


             cellular amino acid metabolic process                           methyltransferase;reductase
                                                                             membrane trafficking regulatory protein
             neurotransmitter secretion;intracellular protein transport;endocytosis;synaptic transmission;synaptic transmission
             negative regulation of apoptosis                                protease inhibitor


                                                                            zinc finger transcription cycle
             cell cycle;DNA repair;regulation of transcription from RNA polymerase II promoter;cell factor
             neurological system process;synaptic transmission;synaptic transmission
                                                                            DNA helicase;helicase
             regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
             mesoderm development;mammary gland development

orf114;ortholog




4orf109;ortholog
                                                                             transcription factor;nucleic acid binding
             visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
             negative regulation of apoptosis;protein modification process methyltransferase
rf95;ortholog

                proteolysis                                                   ubiquitin-protein ligase




 n;UBE2CBP;ortholog
6orf65;ortholog
              ion transport                                                   ATP-binding cassette (ABC) transporter;carbohydrate transporte


                mRNA processing;translation                                   mRNA processing factor;nuclease

                complement activation;response to stimulus                    complement component


                translation                                                   esterase




                                                                                synaptic transmission;nerve-nerve synaptic transmission;neurom
                muscle contraction;neurotransmitter secretion;neuromuscular voltage-gated calcium channel;voltage-gated ion channel
                                                                               cysteine protease;cysteine protease;annexin;calmodulin
                induction of apoptosis;induction of apoptosis;proteolysis;induction of apoptosis
                induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis;I-kappaB kinase/NF-kappaB cascade;induc
                neurological system process;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic transmissio

                neurological system process                                   neuropeptide
                                                                              transcription factor;chromatin/chromatin-binding protein
                apoptosis;regulation of transcription from RNA polymerase II promoter;establishment or maintenance of chromatin architecture
134;ortholog




                                                                           chemokine
                immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
                mitosis;mitosis                                            kinase activator
                                               RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter;transc
                cell cycle;RNA elongation from nucleus                     transcription cofactor;kinase activator
                                                                           receptor;defense/immunity protein;cell adhesion molecule
             macrophage activation;cell adhesion;cell adhesion;cellular defense response
                                                                           immunoglobulin
             immune response;cell adhesion;cell motion;cell adhesion;response to stimulusreceptor superfamily;guanyl-nucleotide exchange
                                                                           membrane-bound signaling molecule;cell adhesion molecule
             gamete generation;B cell mediated immunity;signal transduction;cell-cell adhesion;cell motion;signal transduction;cell-cell adhe

                                                                             protein phosphatase;protein phosphatase
            cell cycle;phosphate metabolic process;protein modification process;cell cycle
                                                                             cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                             cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
                                                                             cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;mesoderm development;ner
                                                                             cadherin
            signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;ectoderm development;nervous system developmen
DK5RAP1;ortholog
                                                                             nucleic acid binding;G-protein modulator
            G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad
                                                                             calmodulin
            cell cycle;calcium-mediated signaling;cell cycle;calcium-mediated signaling
 otein 1;CGRRF1;ortholog
            cholesterol metabolic process                                    hydroxylase;oxidase
                                                                             ubiquitin-protein ligase

              intracellular signaling cascade;intracellular signaling cascade G-protein modulator
              intracellular signaling cascade;intracellular signaling cascade G-protein modulator
                                               nucleus                        transcription factor;DNA-directed from RNA polymerase II promo
              regulation of carbohydrate metabolic process;DNA metabolic process;regulation of transcriptionDNA polymerase;chromatin/chr
                                                                              transduction;nerve-nerve synaptic transmission;neuromuscular
              muscle contraction;sensory perception;cation transport;signal cation transporter;acetylcholine receptor;acetylcholine receptor s
              sulfur metabolic process                                        transferase
g protein 2;RSAD2;ortholog
ent of cytoskeleton                            cytoskeleton                   cytoskeletal protein
              muscle contraction;metabolic process                            amino acid kinase;amino acid kinase
              anion transport                                                 anion channel
                                               tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                               tight junction                 tight junction
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                                                              anion channel;transferase
              immune system process;anion transport;oxygen and reactive oxygen species metabolic process;response to toxin
                                                                              membrane trafficking regulatory protein
              neurological system process;lysosomal transport;intracellular protein transport
              transport;proteolysis;protein folding                           chaperone
taining protein 1;CMTM1;ortholog
              cation transport;signal transduction;signal transduction        cyclic nucleotide-gated ion channel;voltage-gated potassium cha
              cation transport;signal transduction;signal transduction        cyclic nucleotide-gated ion channel;voltage-gated potassium cha

             regulation of transcription from RNA polymerase II promoter transcription factor
             regulation of transcription from RNA polymerase II promoter transcription factor;nucleic acid binding
                                              extracellular matrix             extracellular matrix structural protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                              extracellular transduction;cell-cell adhesion;ectoderm development;mesoderm development;ang
             signal transduction;cell-cell adhesion;signal matrix              extracellular matrix structural protein


                                             extracellular matrix       extracellular matrix structural protein
             cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesis;cellular component morpho
                                             extracellular matrix       extracellular matrix structural protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis

                                             actin cytoskeleton              non-motor actin binding protein
            intracellular protein transport;phagocytosis;mitosis;signal transduction;cell motion;mitosis;signal transduction;cellular componen
            proteolysis                                                      metalloprotease;metalloprotease
            proteolysis                                                      metalloprotease;metalloprotease
            nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
ELD1;ortholog
CRIM1;ortholog
                                           actin cytoskeleton
             mesoderm development;muscle organ development                actin family cytoskeletal protein
             G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway




             respiratory electron transport chain;steroid metabolic process oxidase
             translation                                                    ribosomal protein
             respiratory electron transport chain;steroid metabolic process oxygenase
                                                                            chemokine
             immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
             lipid transport;lipid metabolic process                        transfer/carrier protein;enzyme modulator

             cellular amino acid metabolic process                        decarboxylase
                                                                          RNA helicase;helicase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                          RNA helicase;helicase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

              respiratory electron transport chain;metabolic process        dehydrogenase
 ansporter activity                                                         transporter

                                                                               signaling molecule;enzyme receptor linked signal transduction;in
             cell surface receptor linked signal transduction;intracellular signaling cascade;cell surface modulator
                                                                               transmembrane receptor regulatory/adaptor protein
             neurological system process;cell surface receptor linked signal transduction;nerve-nerve synaptic transmission;cell surface rec
             neurological system process                                       transmembrane receptor regulatory/adaptor protein
             neurological system process                                       transmembrane receptor regulatory/adaptor protein
                                                                               dehydrogenase
             respiratory electron transport chain;cellular amino acid catabolic process;protein metabolic process

             nuclear mRNA splicing, via spliceosome                       RNA binding protein
mall GTPase regulator activity;guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor
             proteolysis                                                  metalloprotease;metalloprotease
             proteolysis                                                  serine protease;serine protease
                                                                          hydrolase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process


                                                                          protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                          protein phosphatase;protein phosphatase;kinase inhibitor
             immune system process;cell cycle;JNK cascade;glycolysis;DNA replication;phospholipid metabolic process;protein amino acid
                                                                          homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;ectoderm development;nervous system development

             spermatogenesis                                             nucleic acid binding
                                                                         transcription factor;nucleic acid binding
             female gamete generation;cell cycle;signal transduction;DNA replication;regulation of transcription from RNA polymerase II pro
                                                                         acetyltransferase;acyltransferase;dehydrogenase;hydratase;ligas
             coenzyme metabolic process;vitamin biosynthetic process;carbohydrate metabolic process;fatty acid beta-oxidation
                                                                         hydrolase;chaperone
             polysaccharide metabolic process;protein amino acid glycosylation;protein folding;proteolysis
             protein metabolic process                                   translation elongation factor
             translation                                                 translation elongation factor
                                                                         membrane-bound signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein tyrosine
                                                                         membrane-bound signaling molecule
             transmembrane receptor protein tyrosine kinase signaling pathway;cell-cell signaling;transmembrane receptor protein tyrosine

                                                                            KRAB box transcription factor;nucleic acid binding
             cell cycle;regulation of transcription from RNA polymerase II promoter;cell cycle;ectoderm development;mesoderm developmen
                                               actin cytoskeleton           non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
             cellular amino acid biosynthetic process;translation           translation initiation factor;isomerase
             translation                                                    translation initiation factor
            translation                                                      translation initiation factor
                                             ribonucleoprotein complex       ribonucleoprotein
            mRNA 3'-end processing;ectoderm development;nervous system development
                                                                             transcription factor;signaling molecule
            immune system process;intracellular signaling cascade;transcription from RNA polymerase II promoter;intracellular signaling ca
                                                                             acetyltransferase
            purine base metabolic process                                    nucleotide phosphatase;nucleotide phosphatase
                                                                             tyrosine protein kinase receptor;tyrosine protein kinase receptor;p
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
                                                                             tyrosine protein kinase receptor;tyrosine protein kinase receptor;p
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
                                                                             tyrosine protein kinase receptor;tyrosine protein kinase receptor;p
            transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
            intracellular protein transport;vesicle-mediated transport       membrane traffic protein;G-protein modulator
            phosphate metabolic process;protein amino acid phosphorylation   protein kinase;protein kinase
                                                                             oxidoreductase
            respiratory electron transport chain;intracellular protein transport;vesicle-mediated transport;protein folding
chondrial;ETFA;ortholog
                                                                             transcription factor;signaling molecule;nucleic acid binding
            cell surface receptor linked signal transduction;MAPKKK cascade;regulation of transcription from RNA polymerase II promoter;
            polysaccharide metabolic process;protein amino acid glycosylationglycosyltransferase
            immune system process;proteolysis;blood coagulation              serine protease;serine protease




             tRNA aminoacylation for protein translation                    aminoacyl-tRNA synthetase




                                           extracellular transduction;signal transduction;mesoderm development;skeletal system developm
             visual perception;sensory perception;signal matrix             signaling molecule;extracellular matrix glycoprotein;extracellular m
             proteolysis
             proteolysis
             proteolysis
             metabolic process
             mesoderm development;muscle organ development
                                                                            immunoglobulin receptor superfamily;immunoglobulin receptor to
             B cell mediated immunity;natural killer cell activation;macrophage activation;signal transduction;signal transduction;response su
             transcription from RNA polymerase II promoter                  zinc finger transcription factor
                                                                             tyrosine kinase
             neurological system process;transmembrane receptor protein growth factor signaling pathway;cell-cell signaling;transmembra
                                                                            growth factor
             transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein tyrosine kinase signaling p

                                                                              tyrosine protein kinase receptor;tyrosine protein cascade;negativ
              negative regulation of apoptosis;cell surface receptor linked signal transduction;MAPKKK cascade;JAK-STAT kinase receptor;p
                                                                              transcription factor;nucleic acid binding
              visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
ause currently there is support for the transcript but not for the protein.
 genome annotation processing.
 genome annotation processing.
ause it is now thought that this gene is a pseudogene.


ause it is a nonsense-mediated mRNA decay (NMD) candidate.
                                               morphogenesis;cellular component morphogenesis;cellular component morphogenesis
               cell motion;cellular component actin cytoskeleton                non-motor actin binding protein
                                               extracellular matrix             receptor;extracellular matrix protein
               cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
               respiratory electron transport chain;metabolic process           oxygenase
FNDC5;ortholog
                                                                            transcription factor;nucleic acid binding
            visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                            transcription factor;nucleic acid binding
            visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                            transcription factor;nucleic acid binding
            visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;
                                                                            transcription factor;nucleic acid binding
            visual perception;sensory perception;cell cycle;cell surface receptor linked signal transduction;carbohydrate metabolic process;


                                                                          enzyme modulator
             cellular amino acid catabolic process                        transferase;deaminase
             metabolic process                                            dehydrogenase
             immune system process;protein amino acid glycosylation       glycosyltransferase
             cation transport                                             cation transporter
             cell cycle;proteolysis;cell cycle                            enzyme modulator
ent of cytoskeleton;microtubule binding        microtubule                non-motor microtubule binding protein
             transcription from RNA polymerase II promoter                transcription factor
                                                                          GABA receptor;GABA receptor
             neurological system process;anion transport;signal transduction;nerve-nerve synaptic transmission;signal transduction;nerve-n


 GALNT2;ortholog
            monosaccharide metabolic process                                epimerase/racemase
            glycolysis                                                      dehydrogenase

                                                                             zinc finger transcription factor;nuclease
              regulation of transcription from RNA polymerase II promoter;endoderm development;mesoderm development;heart developme
              mesoderm development;muscle organ development                  growth factor
                                                                             growth factor
              female gamete generation;mesoderm development;skeletal system development
                                                                             neurotrophic factor
              neurological system process;negative regulation of apoptosis;transmembrane receptor protein tyrosine kinase signaling pathwa
                                               gap junction
              signal transduction;signal transduction                        gap junction
                                               heterotrimeric G-protein complex
                                                                             heterotrimeric G-protein
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway
                                               heterotrimeric G-protein complex
                                                                             hydrolase;heterotrimeric G-protein
              G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling pathway

              monosaccharide metabolic process                             isomerase;hydrolase
                                                                           G-protein receptor protein
              G-protein coupled receptor protein signaling pathway;G-protein coupled coupled receptorsignaling pathway




                                                                               metabolic process;steroid metabolic process;response to stress;
              immune system process;oxygen and reactive oxygen species peroxidase
                                                                               transmembrane receptor regulatory/adaptor protein
              cell surface receptor linked signal transduction;cell surface receptor linked signal transduction

              general transcription from RNA polymerase II promoter         transcription cofactor;nucleic acid binding
              transcription initiation from RNA polymerase II promoter      transcription factor;nucleic acid binding
              glycogen metabolic process                                    glycosyltransferase

                                            actin cytoskeleton             basic helix-loop-helix transcription factor;non-motor actin binding
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;cellular component morphogenesis;cellular component

              proteolysis                                                ubiquitin-protein ligase
              meiosis;nuclear mRNA splicing, via spliceosome;meiosis     DNA helicase;RNA helicase;mRNA splicing factor;helicase;hydro
                                           perception;sensory            transporter;apolipoprotein;membrane-bound signaling molecule;r
              immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s
              proteolysis                                                ubiquitin-protein ligase
hatase activity;nucleotide phosphatase activity                                nucleotide phosphatase;nucleotide phosphatase
               DNA repair                                                      damaged DNA-binding protein


                                           MHC protein defense           major histocompatibility complex antigen
              antigen processing and presentation;cellularcomplex response
                                           MHC of peptide or polysaccharide antigen via MHC class II;cellular defense response
              antigen processing and presentation protein complex        major histocompatibility complex antigen


                                                                           homeobox transcription factor;nucleic acid binding
              regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
              proteolysis                                                  metalloprotease;metalloprotease


                                                                             interferon superfamily
              response to interferon-gamma;macrophage activation;induction of apoptosis;negative regulation of apoptosis;cytokine-mediate
              signal transduction;cell-matrix adhesion;signal transduction;cell-matrix adhesion
                                                                             kinase;kinase
                                                                             interleukin superfamily
              immune response;macrophage activation;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling p
                                                                             type I cytokine
              cytokine-mediated signaling pathway;cytokine-mediated signaling pathway receptor
                                                                             type I cytokine receptor
              immune system process;cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                             type I cytokine
              cytokine-mediated signaling pathway;cytokine-mediated signaling pathway receptor

                                                                                   type I cytokine receptor
              natural killer cell activation;cytokine-mediated signaling pathway;JAK-STAT cascade;MAPKKK cascade;cell-cell signaling;cytok
                                                                                   immunoglobulin receptor superfamily;immunoglobulin receptor
              natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stimulus su
              purine base metabolic process                                        dehydrogenase
              metabolic process                                                    methyltransferase
              cell surface receptor linked signal transduction;proteolysis;cell surface receptor linked signal transduction
              immune system process                                                immunoglobulin receptor superfamily;immunoglobulin receptor su
              cytokine-mediated signaling pathway;transmembrane receptor protein tyrosine kinase signaling pathway;MAPKKK cascade;cyt

                                                                          receptor
                                                                          voltage-gated
            muscle contraction;neuronal action potential propagation;cation transport potassium channel;voltage-gated ion channel
            cation transport                                              voltage-gated potassium channel;voltage-gated ion channel
            cation transport                                              voltage-gated potassium channel;voltage-gated ion channel
            cation transport                                              voltage-gated potassium channel;voltage-gated ion channel
-pentakisphosphate kinase 2;HISPPD1;ortholog




              cell motion                      extracellular matrix       extracellular matrix structural protein
              regulation of transcription from RNA polymerase II promoter KRAB box transcription factor

                                                                           lipase
                                                                           homeobox transcription development;hemopoiesis
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;gut mesodermfactor;zinc finger transcription factor;nucl

              gamete generation;apoptosis


              intracellular protein transport   microtubule                    microtubule binding motor protein
              mitosis;mitosis              microtubule                      microtubule binding motor protein
                                                                            glucosidase;glycosidase
              carbohydrate metabolic process;translation;protein modification process
                                           actin component                  non-motor actin binding protein
              neurological system process;cellularcytoskeletonmorphogenesis;cellular component morphogenesis;cellular component morph

                                          intermediate filament cytoskeleton
                                                                         structural protein;intermediate filament
              cellular component morphogenesis;cellular component morphogenesis;cellular component morphogenesis
                                          intermediate filament cytoskeleton
                                                                         structural protein;intermediate filament
              cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morphogen




              tRNA aminoacylation for protein translation                          aminoacyl-tRNA synthetase
                                                                                   non-receptor tyrosine protein kinase;non-receptor tyrosine protein
              female gamete generation;immune system process;carbohydrate transport;cell cycle;intracellular signaling cascade;carbohydra
                                                                                   transfer/carrier protein;isomerase
              muscle contraction;transport;intracellular signaling cascade;fatty acid biosynthetic process;steroid metabolic process;intracellul
              regulation of transcription from RNA polymerase II promoter nucleic acid binding
                                                                                   immunoglobulin receptor superfamily;immunoglobulin receptor
              natural killer cell activation;signal transduction;cell-cell signaling;signal transduction;cell-cell signaling;response to stimulus su
                                                 actin cytoskeleton                structural protein;actin family cytoskeletal protein
              gamete generation;cell motion;cellular component morphogenesis;cellular component morphogenesis;cellular component morp
                                                 cell junction                     cell junction protein;cell adhesion molecule
              neurological system process;cell adhesion;cell adhesion;cellular component morphogenesis;cellular component morphogenesi
ppressed because currently there is support for the transcript but not for the protein.
ause currently there is support for the transcript but not for the protein.
                                                                                   transcription cofactor
              transcription from RNA polymerase II promoter;ectoderm development;nervous system development
                                                 actin cytoskeleton                non-motor actin binding protein
              cellular component morphogenesis;cellular component morphogenesis;mesoderm development;cellular component morphoge
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
because it is now thought that this gene is a pseudogene.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
y suppressed because it is now thought that this gene does not encode a protein.
 genome annotation processing.
ause currently there is insufficient support for the transcript and the protein.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
because currently there is support for the transcript but not for the protein.
 genome annotation processing.
 quence does not appear to represent a valid product.

quence does not appear to represent a valid product
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
because currently there is insufficient support for the transcript and the protein.
genome annotation processing.
because it is now thought that this gene is a pseudogene.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.
genome annotation processing.

 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
because it is now thought that this gene does not encode a protein.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
y suppressed because it is now thought that this gene is a pseudogene.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
 genome annotation processing.
ause currently there is support for the transcript but not for the protein.
y suppressed because it is now thought that this gene is a pseudogene.
 genome annotation processing.
 genome annotation processing.
ause currently there is support for the transcript but not for the protein.
                                               adhesion;cell adhesion
             female gamete generation;cell extracellular matrix                receptor;extracellular matrix glycoprotein
                                                                                apoptosis;cytokine-mediated signaling
             natural killer cell activation;macrophage activation;induction oftumor necrosis factor family member pathway;cell-cell signaling
             cell adhesion;cell adhesion                                       receptor;immunoglobulin superfamily cell adhesion molecule
             gamete generation;apoptosis
             phosphate metabolic process;protein amino acid phosphorylation    protein kinase;protein kinase
             cellular amino acid metabolic process                             nucleotidyltransferase
                                                                               cytokine
             signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
             negative regulation of apoptosis                                  ubiquitin-protein ligase
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                               extracellular matrix            extracellular matrix glycoprotein
 genome annotation processing.
 genome annotation processing.

             muscle contraction              actin cytoskeleton             actin family cytoskeletal protein;calmodulin
             protein amino acid phosphorylation                             protein kinase;protein kinase
                                             actin cytoskeleton             non-motor actin binding morphogenesis;cellular component morp
             signal transduction;cell adhesion;signal transduction;cell adhesion;cellular component protein
             proteolysis                     extracellular matrix           metalloprotease;metalloprotease;extracellular matrix protein
                                             microtubule
             mitosis;mitosis;chromosome segregation                         microtubule binding motor protein
             translation                                                    ribosomal protein

             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
             translation                                                    ribosomal protein
                                                                            receptor
             B cell mediated immunity;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;respon
                                            mitochondrion;organelle         dehydrogenase;ligase;hydrolase
             purine base metabolic process;cellular amino acid biosynthetic process
             translation                                                    translation initiation factor;hydrolase
                                                                            phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process

                                                                            kinase;kinase
             cholesterol metabolic process;protein amino acid phosphorylation
                                              microtubule                   hydrolase;small GTPase;microtubule family cytoskeletal protein
             intracellular protein transport;endocytosis;cellular component morphogenesis;cellular component morphogenesis;cellular comp
                                                                            basic helix-loop-helix of transcription from RNA polymerase
             induction of apoptosis;cell cycle;MAPKKK cascade;induction of apoptosis;regulationtranscription factor;nucleic acid binding II pr

             respiratory electron transport chain                          dehydrogenase

                                                                           receptor
             regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process


                                                                        immunoglobulin superfamily cell adhesion molecule
             cell adhesion;cell adhesion;ectoderm development;nervous system development
                                                                        ubiquitin-protein ligase
             gamete generation;cell motion;ectoderm development;nervous system development
                                                                        transcription factor
             immune system process;regulation of transcription from RNA polymerase II promoter;mesoderm development;cellular defense
             transcription from RNA polymerase II promoter              transcription factor;nucleic acid binding
                                            actin cytoskeleton          non-motor actin binding protein
             cellular component morphogenesis;cellular component morphogenesis;ectoderm development;cellular component morphogen
              immune response;response to stimulus                          oxidase
              intracellular protein transport;nuclear transport
              regulation of transcription from RNA polymerase II promoter nuclear hormone receptor;receptor;nucleic acid binding
                                                                            nuclear promoter;signal transduction
              signal transduction;regulation of transcription from RNA polymerase II hormone receptor;receptor
                                                perception;sensory          transporter;apolipoprotein;membrane-bound signaling molecule;r
              immune system process;visualextracellular matrix perception;intracellular protein transport;endocytosis;vitamin transport;cell s
              protein targeting;signal transduction;signal transduction     enzyme modulator
              purine base metabolic process                                 nucleotide phosphatase;nucleotide phosphatase

;NUDT22;ortholog
           purine base metabolic process                               pyrophosphatase
           regulation of transcription from RNA polymerase II promoter transcription factor




r activity;transcription factor activity                                     transcription factor
               female gamete generation;fertilization;proteolysis            serine protease;serine protease
               mRNA polyadenylation                                          RNA binding protein
                                                                             membrane trafficking regulatory protein
               intracellular signaling cascade;protein amino acid phosphorylation;intracellular signaling cascade
                                                                             esterase
               transcription from RNA polymerase II promoter;ectoderm development;nervous system development
               immune system process;phospholipid metabolic process          esterase
               mRNA polyadenylation
               transcription from RNA polymerase II promoter                 kinase inhibitor
                                                                             chemokine
               immune response;cytokine-mediated signaling pathway;cell-cell signaling;cytokine-mediated signaling pathway;cell-cell signalin
                                                                             glycosyltransferase
               immune system process;DNA repair;protein amino acid ADP-ribosylation;response to stress

                regulation of transcription from RNA polymerase II promoter basic helix-loop-helix transcription factor
                                                                                 homeobox transcription factor;DNA binding protein
                regulation of transcription from RNA polymerase II promoter;segment specification;ectoderm development;nervous system dev
                                                                                 cadherin
                signal transduction;cell-cell adhesion;signal transduction;cell-cell adhesion;embryonic development
                mitosis;protein amino acid phosphorylation;mitosis               non-receptor serine/threonine protein kinase;non-receptor serine
 r activity;transcription factor activity;transcription cofactor activity        transcription cofactor
                                                                                 tyrosine         kinase receptor;tyrosine pathway;protein amino a
                gamete generation;immune system process;transmembrane receptor protein tyrosine kinase signaling protein kinase receptor;p
                                                   actin cytoskeleton            non-motor actin binding morphogenesis;cellular component morp
                muscle contraction;cell motion;cellular component morphogenesis;cellular component protein
                cellular amino acid metabolic process                            decarboxylase
 ;PELP1;ortholog
                                                                                 neuropeptide
                neurological system process;G-protein coupled receptor protein signaling pathway;G-protein coupled receptor protein signaling
                intracellular protein transport;peroxisomal transport
                intracellular protein transport;peroxisomal transport            transfer/carrier protein
                mitosis;protein amino acid phosphorylation;mitosis               non-receptor serine/threonine protein kinase;non-receptor serine
                protein amino acid lipidation                                    acyltransferase
                                                                                 acetyltransferase;zinc finger transcription factor;chromatin/chrom
                induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;protein amino acid acetylation;cell
er 1;PHLDA1;ortholog
                                                                                 kinase;kinase
                protein targeting;endocytosis;negative regulation of apoptosis;cell surface receptor linked signal transduction;negative regulatio
                                                                                 glycosyltransferase
                phospholipid metabolic process;protein amino acid lipidation;translation
                cation transport;endoderm development                            ion channel
                                                                                 kinase inhibitor
                intracellular signaling cascade;intracellular signaling cascade;mesoderm development;muscle organ development
           lipid metabolic process                                           phospholipase;annexin;calmodulin
           regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
           lipid metabolic process                                           phospholipase
member 1;PLEKHA1;ortholog
member 2;PLEKHO2;ortholog
                                                                              process;blood coagulation
           immune system process;lipid transport;phospholipid metabolictransfer/carrier protein
                                                                             tyrosine protein kinase receptor;signaling molecule;tyrosine prote
           transmembrane receptor protein tyrosine kinase signaling pathway;protein amino acid phosphorylation;transmembrane recepto
                                                                             neuropeptide
           signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
           proteolysis                                                       ubiquitin-protein ligase
           DNA repair                                                        nucleotide kinase;nucleotide phosphatase;nucleotide kinase;nucl
           cell cycle;DNA replication;cell cycle                             nucleotidyltransferase;DNA-directed DNA polymerase
           general transcription from RNA polymerase II promoter             nucleotidyltransferase;DNA-directed RNA polymerase
           mesoderm development;heart development

            regulation of transcription from RNA polymerase II promoter homeobox transcription factor
                                                                        chemokine
            response to interferon-gamma;macrophage activation;cytokine-mediated signaling pathway;JNK cascade;I-kappaB kinase/NF-
            protein targeting
            glycogen metabolic process                                  phosphatase modulator
hosphatase activity;phosphoprotein phosphatase activity                 protein phosphatase;protein phosphatase

             mitosis;cytokinesis;mitosis                                 kinase activator
                                                                         non-receptor serine/threonine
             calcium-mediated signaling;protein amino acid phosphorylation;calcium-mediated signaling protein kinase;transfer/carrier prote


             lipid transport;lipid metabolic process                            enzyme modulator
                                                                                receptor
             lipid transport;intracellular protein transport;exocytosis;cell surface receptor linked signal transduction;lipid metabolic process;c

                                                                               amino phosphatase;protein phosphatase
             protein targeting;signal transduction;cell-cell adhesion;protein proteinacid phosphorylation;cell motion;signal transduction;cell-ce
                                                                               protein signal transduction;cell-matrix adhesion;cell-cell adhesion
             immune system process;protein targeting;cell surface receptor linked phosphatase;protein phosphatase
                                                                               protein phosphatase;protein phosphatase
             cell cycle;cell surface receptor linked signal transduction;intracellular signaling cascade;protein amino acid phosphorylation;cell
                                                                               receptor;protein acid phosphorylation;cell surface
             cell surface receptor linked signal transduction;cell-cell adhesion;protein aminophosphatase;protein phosphatase receptor linke
             respiratory electron transport chain;protein modification process oxidase

                                                                            small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
                                                                            small GTPase
             intracellular protein transport;receptor-mediated endocytosis;intracellular signaling cascade;intracellular signaling cascade
             B cell mediated immunity;DNA recombination;response to stimulusendodeoxyribonuclease;nuclease;hydrolase


             protein targeting;nuclear transport                             G-protein modulator
             signal transduction;signal transduction                         G-protein modulator
                                                                             signaling development
             intracellular signaling cascade;intracellular signaling cascade;ectoderm molecule
                                                                             transcription factor
             antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;cellular defense response

             proteolysis                                                      serine protease;serine protease
             regulation of transcription from RNA polymerase II promoter zinc finger transcription factor
             transcription from RNA polymerase II promoter                    zinc finger transcription factor
                                                                              peptide hormone
             negative regulation of apoptosis;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor p
                                                                              RNA polymerase II promoter;protein metabolic
             intracellular signaling cascade;regulation of transcription from transcription cofactor;ubiquitin-protein ligase process;intracellu
             proteolysis                                                      ubiquitin-protein ligase


             mRNA capping                                                     nucleotidyltransferase;phosphatase;phosphatase

             translation                                                      ribosomal protein
                                                                              carbohydrate transporter;cation transporter
             cation transport;carbohydrate transport;carbohydrate metabolic process
                                              extracellular matrix            receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                              phosphatase;phosphatase
                                                                              ligand-gated ion channel;ligand-gated ion channel
             muscle contraction;cation transport;calcium-mediated signaling;calcium-mediated signaling
             regulation of transcription from RNA polymerase II promoter zinc finger transcription factor;nucleic acid binding
             immune system process                                            enzyme modulator
             regulation of transcription from RNA polymerase II promoter homeobox transcription factor;nucleic acid binding
                                                                              phosphatase;phosphatase
             spermatogenesis;intracellular protein transport;vesicle-mediated transport;phospholipid metabolic process
                                                                              receptor
             macrophage activation;lipid transport;apoptosis;signal transduction;lipid metabolic process;signal transduction;cellular compone

             tRNA aminoacylation for protein translation                aminoacyl-tRNA synthetase
                                                                        dehydratase;epimerase/racemase;deaminase
             neurological system process;synaptic transmission;gluconeogenesis;cellular amino acid biosynthetic process;cellular amino ac
             intracellular protein transport                            transfer/carrier protein
                                              SNARE
             intracellular protein transport;exocytosiscomplex          SNARE protein
             intracellular protein transport;vesicle-mediated transport membrane traffic protein;phospholipase


            proteolysis                                                       serine protease inhibitor
            proteolysis                                                       serine protease inhibitor
            nuclear mRNA splicing, via spliceosome                            mRNA splicing factor
            nuclear mRNA splicing, via spliceosome
;SGEF;ortholog
            intracellular signaling cascade;intracellular signaling cascade   signaling molecule
            intracellular signaling cascade;intracellular signaling cascade
            neurological system process;proteolysis                           ubiquitin-protein ligase

                                                                              DNA helicase;helicase
             regulation of transcription from RNA polymerase II promoter;DNA repair;DNA recombination;establishment or maintenance of c
             protein amino acid glycosylation                                 glycosyltransferase
             immune system process                                            type I cytokine receptor
             cell adhesion;cell adhesion                                      G-protein modulator
                                                                              chemokine
             cytokine-mediated signaling pathway;cytokine-mediated signaling pathway
                                                                              chromatin/chromatin-binding of chromatin architecture;establishm
             regulation of transcription from RNA polymerase II promoter;establishment or maintenance protein;deacetylase
                                                                              transmembrane receptor regulatory/adaptor protein;signaling mo
             immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein ty
                                                                              transmembrane receptor regulatory/adaptor protein;signaling mo
             immune system process;transmembrane receptor protein tyrosine kinase signaling pathway;transmembrane receptor protein ty
             cation transport                                                 cation transporter
             transport                                                        mitochondrial carrier protein;transfer/carrier protein
                                              mitochondrial inner membrane;organelle
             carbohydrate transport;carbohydrate metabolic process            carbohydrate transporter
             ion transport                                                    transporter
             cation transport;extracellular transport                         cation transporter
             immune system process;cell cycle;cell cycle;cellular defense response
                                              extracellular matrix            receptor;extracellular matrix protein
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
                                                                              transcription kinase
             immune system process;transmembrane receptor protein serine/threonine factor signaling pathway;intracellular signaling casc
              protein folding                                              chaperone
                                                                           nucleic acid binding;G-protein modulator
              G-protein coupled receptor protein signaling pathway;cell adhesion;G-protein coupled receptor protein signaling pathway;cell ad

              intracellular protein transport                                  kinase;kinase
              transcription initiation from RNA polymerase II promoter         transcription factor
                                                                                endocytosis;lipid metabolic process
              lipid transport;intracellular protein transport;receptor-mediatedtransporter;receptor
              regulation of transcription from RNA polymerase II promoter HMG box transcription factor;nucleic acid binding
              regulation of transcription from RNA polymerase II promoter HMG box transcription factor;nucleic acid binding
                                                                                 promoter
              immune system process;transcription from RNA polymerase IItranscription cofactor;zinc finger transcription factor;DNA binding
                                                                                 promoter
              immune system process;transcription from RNA polymerase IItranscription cofactor;zinc finger transcription factor;DNA binding
              spermatogenesis;cell motion microtubule                          microtubule family cytoskeletal protein


             nuclear mRNA splicing, via spliceosome
                                                                              dehydratase;epimerase/racemase;deaminase
             neurological system process;synaptic transmission;cellular amino acid biosynthetic process;cellular amino acid catabolic proce
             phosphate metabolic process;protein amino acid phosphorylation   protein kinase;protein kinase
                                                                              non-receptor serine/threonine protein kinase;non-receptor serine
             neurological system process;mitosis;calcium-mediated signaling;protein amino acid phosphorylation;cytokinesis;mitosis;calcium
TK11IP;ortholog
                                                                              transcription factor;nucleic acid binding
             transcription initiation from RNA polymerase II promoter;regulation of transcription from RNA polymerase II promoter
             complement activation;response to stimulus                       complement component
                                                                              ATP
             immune system process;cation transport;cellular defense responsesynthase
             cation transport;vitamin transport;vitamin metabolic process cation transporter;transfer/carrier protein
                                                                              DNA binding protein;RNA binding protein;deaminase;kinase activ
             spermatogenesis;response to interferon-gamma;neurological system process;apoptosis;cell cycle;purine base metabolic proce
                                                                              transcription factor
             immune system process;regulation of transcription from RNA polymerase II promoter;mesoderm development;hemopoiesis
                                                                              growth factor
             cell surface receptor linked signal transduction;cell surface receptor linked signal transduction
             RNA catabolic process                                            exoribonuclease;nuclease;esterase
                                                                              receptor
             nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
                                                                              transcription cofactor;zinc maintenance of chromatin architectur
             regulation of transcription from RNA polymerase II promoter;proteolysis;establishment orfinger transcription factor;nucleic acid b
                                              mitochondrial inner membrane;organelle
                                                                              mitochondrial
             intracellular protein transport;mitochondrial transport;mitochondrial transportcarrier protein;transfer/carrier protein
             sensory perception of sound;sensory perception;protein targeting
                                                                              cation transporter
             sensory perception of sound;sensory perception;cation transport;protein targeting;ectoderm development;nervous system deve
             vitamin metabolic process;pentose-phosphate shunt                transketolase
                                                                              non-receptor serine/threonine protein kinase;non-receptor serine
             mitosis;intracellular signaling cascade;DNA repair;DNA replication;protein amino acid phosphorylation;cytokinesis;mitosis;intrac
                                              extracellular matrix            receptor;extracellular matrix protein
             cytokine-mediated signaling pathway;cytokine-mediated signaling pathway

 2;TMCC2;ortholog




                                                                           receptor
              immune system process;cell surface receptor linked signal transduction;cell surface receptor linked signal transduction;cellular
                                           actin cytoskeleton              actin family cytoskeletal development;muscle organ developmen
              muscle contraction;calcium-mediated signaling;calcium-mediated signaling;mesodermprotein;calmodulin
                                           development;muscle organ development actin binding protein
              muscle contraction;mesoderm actin cytoskeleton               non-motor
              protein targeting;nuclear transport                              transporter;transfer/carrier protein
              regulation of transcription from RNA polymerase II promoter transcription cofactor;nucleic acid binding
              muscle contraction               actin cytoskeleton              actin binding motor protein
              protein folding                                                  chaperone
                                                                               HMG box transcription factor;chromatin/chromatin-binding protein
              nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;establishment or maintenance of chromatin architecture
                                                                                promoter
              DNA repair;regulation of transcription from RNA polymerase IItranscription cofactor;nucleic acid binding
                                                                               transcription factor
              induction of apoptosis;cell cycle;regulation of transcription from RNA polymerase II promoter;DNA repair;cell cycle
                                                                               signaling molecule
              immune system process;induction of apoptosis;cytokine-mediated signaling pathway;JNK cascade;I-kappaB kinase/NF-kappaB
              intracellular protein transport
                                                                               ubiquitin-protein ligase
              synaptic vesicle exocytosis;intracellular protein transport;exocytosis;signal transduction;synaptic transmission;proteolysis;signa
                                                                               transcription cofactor;nucleic chromatin architecture;establishme
              transcription from RNA polymerase II promoter;proteolysis;establishment or maintenance ofacid binding;ubiquitin-protein ligase
                                                                               transcription cofactor;nucleic chromatin architecture;establishme
              transcription from RNA polymerase II promoter;proteolysis;establishment or maintenance ofacid binding;ubiquitin-protein ligase
              proteolysis                                                      ubiquitin-protein ligase
                                                                               ion channel
              visual perception;sensory perception;cation transport;calcium-mediated signaling;calcium-mediated signaling
              transport
              protein folding                                                  chaperone

              protein metabolic process        microtubule                     ligase;microtubule family cytoskeletal protein
                                               tubulin complex;tubulin complex tubulin
              intracellular protein transport;mitosis;cell motion;mitosis;chromosome segregation;cellular component morphogenesis;cellular c
                                                                               non-receptor tyrosine protein kinase;non-receptor tyrosine protein
              immune system process;apoptosis;apoptosis;protein amino acid phosphorylation;apoptosis;response to stress;cellular defense

             proteolysis;protein modification process                     ligase
             proteolysis;protein modification process                     transfer/carrier protein;ubiquitin-protein ligase
             mitosis;mitosis                                              membrane trafficking regulatory protein
                                                                          zinc finger transcription factor
             nucleobase, nucleoside, nucleotide and nucleic acid transport;cell cycle;nucleobase, nucleoside, nucleotide and nucleic acid m
 MC1;ortholog
 quence does not appear to represent a valid product.

             proteolysis                                                  cysteine protease;cysteine protease
             proteolysis                                                  cysteine protease;cysteine protease
             proteolysis                                                  cysteine protease;cysteine protease
             gamete generation;proteolysis                                cysteine protease;cysteine protease
             proteolysis                                                  cysteine protease;cysteine protease
             proteolysis                                                  cysteine protease;cysteine protease
             proteolysis                                                  cysteine protease;cysteine protease
             gamete generation;proteolysis                                cysteine protease;cysteine protease
                                                                          homeobox transcription factor;DNA binding protein
             regulation of transcription from RNA polymerase II promoter;dorsal/ventral axis specification;ectoderm development;nervous sy
             lysosomal transport;intracellular protein transport
otein 2A;VSTM2A;ortholog
                                                                          receptor;defense/immunity adhesion
             immune system process;signal transduction;cell-cell adhesion;signal transduction;cell-cellprotein
mall GTPase regulator activity;guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor
 28 protein;WBSCR28;ortholog
             protein targeting;signal transduction;signal transduction    enzyme modulator

              transcription from RNA polymerase II promoter
                                                                                growth factor
              cell cycle;cell surface receptor linked signal transduction;cell-cell signaling;cell motion;cell cycle;cell surface receptor linked sign
                                                                                signaling molecule
              signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
                                                                                signaling molecule
              signal transduction;cell-cell signaling;signal transduction;cell-cell signaling
              JAK-STAT cascade;JAK-STAT cascade;mesoderm development
             proteolysis                                                     ubiquitin-protein ligase
             intracellular protein transport;vesicle-mediated transport
                                                                             nucleic acid binding

               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   transcription cofactor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor;nucleic acid binding
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   zinc finger transcription factor;DNA binding protein
r activity;transcription factor activity                                     KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor
               regulation of transcription from RNA polymerase II promoter   KRAB box transcription factor;nucleic acid binding

            regulation of transcription from RNA polymerase II promoter KRAB box transcription factor
ZPLD1;ortholog
SWIM5;ortholog
             Pathway
             Blood coagulation->alpha-2-macroglobulin;;

ette (ABC) transporter
ette (ABC) transporter
ette (ABC) transporter




metalloprotease

ase;protein phosphatase

             Wnt signaling pathway->Transforming growth factor beta activated kinase 1;;TGF-beta signaling pathway->TGFbetareceptor I;;
             TGF-beta signaling pathway->TGFbetareceptor II;;TGF-beta signaling pathway->TGFbetareceptors;;;
metalloprotease
             Ornithine degradation->Ornithine decarboxylase;;
             Endothelin signaling pathway->3',5'-cyclic AMP synthetase;;GABA-B_receptor_II_signaling->Adenylate cyclase;;Heterotrimeric
             Wnt signaling pathway->NFAT Target Genes;;De novo purine biosynthesis->Adenylosuccinate synthase;;;

             Wnt signaling pathway->Transducin-like Enhance of Split 1-3;;




             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde dehydrogen




             Angiogenesis->Angiopoietin-2;;




ng;G-protein modulator


              EGF receptor signaling pathway->Epidermal growth factor;;
;cysteine protease

 exchange factor
            Wnt signaling pathway->Switched/Sucrose Non Fermentation;;
              Wnt signaling pathway->Beta-Arrestin;;




immunity protein;cell adhesion molecule




cleotide phosphatase;nucleotide phosphatase

t;cellular defense response




king regulatory protein
              Apoptosis signaling pathway->Cellular inhibitor of apoptosis protein 1 and 2 ;;




              Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
ette (ABC) transporter;carbohydrate transporter;ligase


g factor;nuclease




              Metabotropic glutamate receptor group III pathway->Calcium Channel;;5HT2 type receptor mediated signaling pathway->Ca2+
              Huntington disease->Calpain;;
sis;I-kappaB kinase/NF-kappaB cascade;induction of apoptosis
acellular signaling cascade;synaptic transmission;cell surface receptor linked signal transduction;intracellular signaling cascade;synaptic tran


r;chromatin/chromatin-binding protein




              Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;

ctor;kinase activator
immunity protein;cell adhesion molecule
eceptor superfamily;guanyl-nucleotide exchange factor;immunoglobulin receptor superfamily;cell adhesion molecule
 signaling molecule;cell adhesion molecule

              p53 pathway->Cell division cycle 25C;;
              Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
              Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
              Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;


ng;G-protein modulator




 r;DNA-directed DNA polymerase;chromatin/chromatin-binding protein
             Nicotinic acetylcholine receptor signaling pathway->Nicotinic Acetylcholine Receptor;;Nicotinic acetylcholine receptor signaling p




e;amino acid kinase




              Dopamine receptor mediated signaling pathway->chloride intracellular channel 6;;
king regulatory protein


              Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;
              Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->cGMP-gated ion channel;;


 r;nucleic acid binding
               Integrin signalling pathway->Collagen;;
               Integrin signalling pathway->Collagen;;

              Integrin signalling pathway->Collagen;;
              Integrin signalling pathway->Collagen;;
              Integrin signalling pathway->Collagen;;

inding protein
metalloprotease
metalloprotease
keletal protein
               Angiogenesis->Crk oncogene;;Integrin signalling pathway->Crk;;;




            Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
otein;enzyme modulator

             Adrenaline and noradrenaline biosynthesis->Aromatic L-amino acid decarboxylase;;Dopamine receptor mediated signaling path




e;enzyme modulator
             Huntington disease->Postsynaptic density 95;;
eceptor regulatory/adaptor protein
eceptor regulatory/adaptor protein




 exchange factor
metalloprotease
erine protease
             Axon guidance mediated by semaphorins->Collapsin response mediator protein;;Axon guidance mediated by semaphorins->CR


               Oxidative stress response->MAP Kinase Phosphatases;;
               Oxidative stress response->MAP Kinase Phosphatases;;
ription factor;DNA binding protein


r;nucleic acid binding
acyltransferase;dehydrogenase;hydratase;ligase;epimerase/racemase




 signaling molecule
             Angiogenesis->Ephrin;;

              Angiotensin II-stimulated signaling through G proteins and beta-arrestin->early growth response;;
inding protein
 n factor;isomerase
             PDGF signaling pathway->Ets;;

hatase;nucleotide phosphatase
nase receptor;tyrosine protein kinase receptor;protein kinase
              Angiogenesis->Ephrin Receptor;;
              Angiogenesis->Ephrin Receptor;;
 protein;G-protein modulator
              Alzheimer disease-presenilin pathway->Ire-1;;Alzheimer disease-presenilin pathway->Ire-1 C-terminal fragment;;Alzheimer dise


r;signaling molecule;nucleic acid binding

             Blood coagulation->Thrombin;;Blood coagulation->Prothrombin;;;




e;extracellular matrix glycoprotein;extracellular matrix structural protein;cell adhesion molecule;annexin




eceptor superfamily;immunoglobulin receptor superfamily


             FGF signaling pathway->fibroblast growth factor;;

nase receptor;tyrosine protein kinase receptor;protein kinase
            Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa




              Integrin signalling pathway->Filamin;;Dopamine receptor mediated signaling pathway->filamin A;;;
ular matrix protein
              Nicotine degradation->Flavin-containing monooxygenase;;
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Insulin/IGF pathway-protein kinase B signaling cascade->Forkhead transcription factor;;TGF-beta signaling pathway->Co-activa
             Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1-like 1;;Dopamine receptor mediated




             5-Hydroxytryptamine degredation->Aldehyde Dehydrogenase;;Phenylethylamine degradation->Phenylacetaldehyde dehydrogen




ubule binding protein
             PDGF signaling pathway->Ets;;
ABA receptor




             Glycolysis->Glyceraldehyde 3-phosphate dehydrogenase;;Huntington disease->Glyceraldehyde-3-phosphate dehydrogenase;;;

iption factor;nuclease
               TGF-beta signaling pathway->Transforming growth factor beta;;
               TGF-beta signaling pathway->Transforming growth factor beta;;
               TGF-beta signaling pathway->Transforming growth factor beta;;

             PI3 kinase pathway->Galpha;;Endothelin signaling pathway->guanine nucleotide binding protein q polypeptide;;Metabotropic glu
             Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction->G protein, beta subunit;;Opioid proopiomela

             N-acetylglucosamine metabolism->Glucosamine-6-phosphate deaminase;;




eceptor regulatory/adaptor protein

              General transcription regulation->TFIIA;;Transcription regulation by bZIP transcription factor->TFIIA;;;
r;nucleic acid binding


elix transcription factor;non-motor actin binding protein


A helicase;mRNA splicing factor;helicase;hydrolase
oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;extracellul
hatase;nucleotide phosphatase
nding protein


 tibility complex antigen
 tibility complex antigen
                p53 pathway->High mobility group protein 1;;
                p53 pathway->High mobility group protein 1;;
                Wnt signaling pathway->Wnt Target Genes;;
metalloprotease




              p53 pathway->Insulin-like growth factor-binding protein 3;;

              Inflammation mediated by chemokine and cytokine signaling pathway->Interleukin 2;;




              Interleukin signaling pathway->Receptor subunit alpha;;
eceptor superfamily;immunoglobulin receptor superfamily
              De novo purine biosynthesis->IMP dehydrogenase;;
              Adrenaline and noradrenaline biosynthesis->Phenylethanolamine-N-methyltransferase;;Nicotine degradation->indolethylamine
linked signal transduction
eceptor superfamily;immunoglobulin receptor superfamily
              Interleukin signaling pathway->Insulin receptor substrate family;;Insulin/IGF pathway-protein kinase B signaling cascade->Insul


assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel
assium channel;voltage-gated ion channel




 x structural protein




ription factor;zinc finger transcription factor;nucleic acid binding




ng motor protein
ng motor protein

inding protein

ntermediate filament
ntermediate filament




              Integrin signalling pathway->Src;;Parkinson disease->Rous sarcoma protein tyrosine kinase;;T cell activation->Lck;;;;
otein;isomerase
              Cadherin signaling pathway->Transcription factor 4/Lymphoid enhancer-binding factor;;Alzheimer disease-presenilin pathway->
eceptor superfamily;immunoglobulin receptor superfamily
actin family cytoskeletal protein
in;cell adhesion molecule




inding protein
ular matrix glycoprotein
               Inflammation mediated by chemokine and cytokine signaling pathway->Interleukin 2;;Apoptosis signaling pathway->Tumor nec
globulin superfamily cell adhesion molecule

              FGF signaling pathway->Mitogen-activated protein kinase kinase kinase;;
              S adenosyl methionine biosynthesis->S-Adenosyl methionine synthetase;;

              p53 pathway feedback loops 2->MDM-2;;p53 pathway->Mdm2;;Insulin/IGF pathway-protein kinase B signaling cascade->Mdm2

x glycoprotein




keletal protein;calmodulin

             Alzheimer disease-presenilin pathway->Afadin;;
             Alzheimer disease-presenilin pathway->Matrix metalloprotease;;
ng motor protein




             Formyltetrahydroformate biosynthesis->Methylenetetrahydrofolate dehydrogenase;;
n factor;hydrolase


           Cholesterol biosynthesis->Mevalonate kinase;;
TPase;microtubule family cytoskeletal protein
           Wnt signaling pathway->Wnt Target Genes;;




uperfamily cell adhesion molecule
              Notch signaling pathway->Neuralized;;
              Wnt signaling pathway->NFAT;;B cell activation->NF-AT;;Inflammation mediated by chemokine and cytokine signaling pathway
r;nucleic acid binding
inding protein
receptor;receptor;nucleic acid binding
receptor;receptor
oprotein;membrane-bound signaling molecule;receptor;metalloprotease;serine protease;oxidase;metalloprotease;serine protease;extracellul

hatase;nucleotide phosphatase




             Formyltetrahydroformate biosynthesis->Dihydrofolate reductase;;Folate biosynthesis->Dihydrofolate reductase;;Folate biosynth
erine protease

king regulatory protein




              Inflammation mediated by chemokine and cytokine signaling pathway->Chemokine;;
              FAS signaling pathway->Poly(ADP-ribose) polymerase;;

elix transcription factor
ription factor;DNA binding protein
               Wnt signaling pathway->Cadherin;;Cadherin signaling pathway->Cadherin;;;
ne/threonine protein kinase;non-receptor serine/threonine protein kinase

              Angiogenesis->Platelet-Derived Growth Factor Receptor;;
inding protein


              Opioid proenkephalin pathway->proenkephalin;;Opioid proenkephalin pathway->peptide E;;Opioid proenkephalin pathway->Enk


ne/threonine protein kinase;non-receptor serine/threonine protein kinase

zinc finger transcription factor;chromatin/chromatin-binding protein
nexin;calmodulin




nase receptor;signaling molecule;tyrosine protein kinase receptor;protein kinase

              p53 pathway->PML;;p53 pathway->Promyelocytic leukemia protein;;;
;nucleotide phosphatase;nucleotide kinase;nucleotide phosphatase
rase;DNA-directed DNA polymerase
rase;DNA-directed RNA polymerase




              FGF signaling pathway->protein phosphatase 2A;;


              Wnt signaling pathway->Protein Kinase C;;B cell activation->PKC;;Thyrotropin-releasing hormone receptor signaling pathway->




              Hedgehog signaling pathway->Patched;;

              Integrin signalling pathway->Protein tyrosine phosphatase-PEST;;
ase;protein phosphatase
ase;protein phosphatase
 hosphatase;protein phosphatase


              Huntington disease->Rab8;;PDGF signaling pathway->Ras;;;


clease;nuclease;hydrolase




              Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->Ras;;Angiogenesis->Ras GTPase-Activatin




erine protease




ctor;ubiquitin-protein ligase
rase;phosphatase;phosphatase


sporter;cation transporter
ular matrix protein

               Beta2 adrenergic receptor signaling pathway->ER-type Ca2+ channel;;Beta1 adrenergic receptor signaling pathway->ER-type C
iption factor;nucleic acid binding

ription factor;nucleic acid binding




erase/racemase;deaminase


protein;phospholipase




              Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Rap1 GTPase-activating protein 1;;

             p53 pathway->Sirtuin;;
eceptor regulatory/adaptor protein;signaling molecule
             Interleukin signaling pathway->Src-like protein tyrosine kinase (PTK) family;;

ier protein;transfer/carrier protein


              Adrenaline and noradrenaline biosynthesis->amine translocator;;

ular matrix protein
              TGF-beta signaling pathway->Inhibitory Smads;;TGF-beta signaling pathway->RSmads;;TGF-beta signaling pathway->I-SMAD
ng;G-protein modulator




ption factor;nucleic acid binding
ption factor;nucleic acid binding
ctor;zinc finger transcription factor;DNA binding protein
ctor;zinc finger transcription factor;DNA binding protein
y cytoskeletal protein




erase/racemase;deaminase

              p53 pathway by glucose deprivation->Serine/threonine protein kinase 11;;

r;nucleic acid binding


;transfer/carrier protein
ein;RNA binding protein;deaminase;kinase activator;defense/immunity protein

             TGF-beta signaling pathway->Transforming growth factor beta;;
nuclease;esterase

ctor;zinc finger transcription factor;nucleic acid binding;ubiquitin-protein ligase
 ier protein;transfer/carrier protein




ne/threonine protein kinase;non-receptor serine/threonine protein kinase
             Toll receptor signaling pathway->Toll-like receptor 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12;;




keletal protein;calmodulin
inding protein
er/carrier protein
ctor;nucleic acid binding


ption factor;chromatin/chromatin-binding protein
ctor;nucleic acid binding
              Huntington disease->P53 tumor suppressor phosphoprotein;;P53 pathway feedback loops 1->P53;;p53 pathway->p53;;p53 pat
              Apoptosis signaling pathway->TNF receptor-associated factor 2;;p53 pathway->TRAF;;;


ctor;nucleic acid binding;ubiquitin-protein ligase
ctor;nucleic acid binding;ubiquitin-protein ligase

              Alzheimer disease-presenilin pathway->Capacitative calcium channels;;




e family cytoskeletal protein

sine protein kinase;non-receptor tyrosine protein kinase


              Parkinson disease->Ubiquitin-conjugating enzyme 6;;
king regulatory protein




;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
;cysteine protease
ription factor;DNA binding protein


immunity protein
 exchange factor




              Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Alzheimer disease-presenilin pathway->Win
              Cadherin signaling pathway->Wingless-type MMTV integration site family member;;Angiogenesis->Wingless-Type MMTV Integ
             Ubiquitin proteasome pathway->Ubiquitin protein ligase E3;;




iption factor;nucleic acid binding

iption factor;DNA binding protein




iption factor;nucleic acid binding
g pathway->TGFbetareceptor I;;TGF-beta signaling pathway->TGFbetareceptors;;;;




enylate cyclase;;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->Adenylyl cyclase;;;;




Phenylacetaldehyde dehydrogenase;;;
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
iated signaling pathway->Ca2+ channel;;Thyrotropin-releasing hormone receptor signaling pathway->Ca2+ channel;;Metabotropic glutamate


signaling cascade;synaptic transmission
cetylcholine receptor signaling pathway->Acetylcholine receptor protein, beta;;;




ion channel;;
ion channel;;
eceptor mediated signaling pathway->Aromatic L-amino acid decarboxylase;;Histamine synthesis->Histidine Decarboxylase;;5-Hydroxytrypta




e mediated by semaphorins->CRMP 3-associated molecule;;Pyrimidine Metabolism->Dihydropyrimidinase;;;;
rminal fragment;;Alzheimer disease-presenilin pathway->Ire-1 N-terminal fragment;;;;




ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
ta signaling pathway->Co-activators or corepressors;;Interleukin signaling pathway->Forkhead in Rhabdomyosarcoma-like 1;;PI3 kinase pat
;;Dopamine receptor mediated signaling pathway->erythrocyte membrane protein band 4.1;;Dopamine receptor mediated signaling pathway-




Phenylacetaldehyde dehydrogenase;;;




-3-phosphate dehydrogenase;;;




 q polypeptide;;Metabotropic glutamate receptor group I pathway->Gq;;Thyrotropin-releasing hormone receptor signaling pathway->G-Protei
ta subunit;;Opioid proopiomelanocortin pathway->G-protein;;5HT1 type receptor mediated signaling pathway->G-protein;;5HT4 type recepto




ease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule
degradation->indolethylamine N-methyltransferase;;;


ase B signaling cascade->Insulin receptor substrate family;;PI3 kinase pathway->Insulin Receptor Substrate;;Insulin/IGF pathway-mitogen ac
cell activation->Lck;;;;

er disease-presenilin pathway->T-cell factor/lymphoid enhancer factor;;Wnt signaling pathway->T cell factor;;;;
signaling pathway->Tumor necrosis factor;;;




ase B signaling cascade->Mdm2;;P53 pathway feedback loops 1->Mdm2;;p53 pathway->Mouse double minute 2;;Insulin/IGF pathway-protein




and cytokine signaling pathway->Nuclear factor of activated T cells;;T cell activation->NF-AT;;;;;
ease;serine protease;extracellular matrix protein;enzyme modulator;cell adhesion molecule




olate reductase;;Folate biosynthesis->Dihydrofolate synthase;;;;




 id proenkephalin pathway->Enkephalin;;Enkephalin release->preproenkephalin mRNA;;Opioid proenkephalin pathway->met-Enkephalin;;En
ne receptor signaling pathway->PKC;;Inflammation mediated by chemokine and cytokine signaling pathway->Protein kinase C;;Alzheimer dis




genesis->Ras GTPase-Activating Protein;;Angiogenesis->GTPase-Activating Protein;;Interleukin signaling pathway->Ras GTPase Activity Pr
or signaling pathway->ER-type Ca2+ channel;;;




TPase-activating protein 1;;




eta signaling pathway->I-SMAD;;;;
53;;p53 pathway->p53;;p53 pathway by glucose deprivation->p53;;p53 pathway feedback loops 2->p53;;P53 pathway feedback loops 1->Tum




sease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;
s->Wingless-Type MMTV Integration Site Family;;Alzheimer disease-presenilin pathway->Wingless-type protein;;Wnt signaling pathway->W
ylyl cyclase;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
hannel;;Metabotropic glutamate receptor group II pathway->Calcium Channel;;Beta1 adrenergic receptor signaling pathway->Ca2+ channel;;
Decarboxylase;;5-Hydroxytryptamine biosynthesis->Aromatic L-amino acid decarboxylase;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
sarcoma-like 1;;PI3 kinase pathway->FOXO;;;;;
or mediated signaling pathway->erythrocyte membrane protein band 4.1-like 2;;;;




or signaling pathway->G-Protein;;Alpha adrenergic receptor signaling pathway->G-Protein;;Muscarinic acetylcholine receptor 1 and 3 signalin
>G-protein;;5HT4 type receptor mediated signaling pathway->G-protein;;Endogenous_cannabinoid_signaling->Gbeta;;Inflammation mediate
Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade->Insulin receptor substrate family;;;;;
e 2;;Insulin/IGF pathway-protein kinase B signaling cascade->Mdm2;;p53 pathway feedback loops 2->MDM-2;;P53 pathway feedback loops
pathway->met-Enkephalin;;Enkephalin release->preproenkephalin;;Opioid proenkephalin pathway->peptide F;;Opioid proenkephalin pathwa
Protein kinase C;;Alzheimer disease-amyloid secretase pathway->Protein kinase C;;EGF receptor signaling pathway->PKC;;Histamine H1 re




thway->Ras GTPase Activity Protein;;PDGF signaling pathway->Ras GTPase Activity Protein;;FGF signaling pathway->p120 Ras GTPase-a
pathway feedback loops 1->Tumor protein p73;;p53 pathway->p53;;;;;;;;




site family member;;;;
ein;;Wnt signaling pathway->Wingless-type MMTV integration site family member;;;;;
aling pathway->Ca2+ channel;;Alzheimer disease-amyloid secretase pathway->L-type calcium channels;;Oxytocin receptor mediated signalin
choline receptor 1 and 3 signaling pathway->Gq;;Wnt signaling pathway->Galpha;;Oxytocin receptor mediated signaling pathway->G-Protein;
 ->Gbeta;;Inflammation mediated by chemokine and cytokine signaling pathway->G beta/gamma subunits;;Thyrotropin-releasing hormone re
2;;P53 pathway feedback loops 1->Mouse double minute 2;;;;;;;;;
F;;Opioid proenkephalin pathway->leu-Enkephalin;;Enkephalin release->Enkephalin;;;;;;;;;;
athway->PKC;;Histamine H1 receptor mediated signaling pathway->PKC;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->Pro




pathway->p120 Ras GTPase-activating protein;;EGF receptor signaling pathway->GAP;;;;;;;;
tocin receptor mediated signaling pathway->Ca2+ channel;;Nicotinic acetylcholine receptor signaling pathway->Calcium Channel;;Beta2 adre
 signaling pathway->G-Protein;;5HT2 type receptor mediated signaling pathway->G-protein;;Histamine H1 receptor mediated signaling pathw
yrotropin-releasing hormone receptor signaling pathway->G-Protein;;Beta3 adrenergic receptor signaling pathway->G-Protein;;Heterotrimeri
1 and 3 signaling pathway->Protein kinase C;;VEGF signaling pathway->Protein Kinase C;;Angiogenesis->Protein Kinase C;;Oxytocin recept
->Calcium Channel;;Beta2 adrenergic receptor signaling pathway->Ca2+ channel;;;;;;;;;;
ceptor mediated signaling pathway->G-Protein;;Cortocotropin releasing factor receptor signaling pathway->G-Protein;;Inflammation mediated
hway->G-Protein;;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway->G protein, beta subunit;;Heterotrime
tein Kinase C;;Oxytocin receptor mediated signaling pathway->PKC;;FGF signaling pathway->PKC;;Endothelin signaling pathway->protein k
Protein;;Inflammation mediated by chemokine and cytokine signaling pathway->Gi/q alpha subunits;;Inflammation mediated by chemokine a
otein, beta subunit;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->G protein-activated inward rectif
in signaling pathway->protein kinase c;;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway->Protein kinas
 ation mediated by chemokine and cytokine signaling pathway->Gq alpha subunit;;;;;;;;;;;;;;
G protein-activated inward rectifying potassium channel;;Angiotensin II-stimulated signaling through G proteins and beta-arrestin->G-protein,
ediated pathway->Protein kinase C;;Metabotropic glutamate receptor group I pathway->Protein kinase C;;5HT2 type receptor mediated sign
and beta-arrestin->G-protein, beta subunit;;Muscarinic acetylcholine receptor 1 and 3 signaling pathway->Gq;;Histamine H2 receptor media
T2 type receptor mediated signaling pathway->PKC;;Apoptosis signaling pathway->Protein kinase C;;;;;;;;;;;;;;;;;;
q;;Histamine H2 receptor mediated signaling pathway->G-Protein;;Opioid proenkephalin pathwa

				
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