Innovative Drug Delivery Systems

T H E W I S C O N S I N University of Wisconsin–Madison Pharmacy Alumni Association Fall 2000 Innovative drug delivery systems are on the way Prof. Joseph Robinson, PhD Useful innovations in drug delivery fit into the following broad categories: • Biocompatible subcutaneous or intramuscular injectable • Reticuloendothelial systems, drug carriers that avoid removal by the liver, spleen, lung, and bone • Bioadhesives that allow localization in mucosal routes of administration • Systems for oral delivery of peptides and proteins • New polymers for tissue engineering • New systems to solubilize new drugs (43% of new drugs are essentially insoluable in water) The UW-Madison has long history of innovation in drug delivery. Prof. Dale E. Wurster (inventor of the air-suspension coating machine) was one of the first scientists in the world to promote transdermal delivery of drugs. Prof. Takeru Higuchi is the inventor of record for the ALZA company’s osmotic tablet. Bioadhesives for drug delivery, invented here, are currently in a vaginal moisturizer, a progesterone product, and various ophthalmic products. In this rich tradition are a group of very talented young School of Pharmacy faculty who will pioneer inventions in modern drug delivery. Two of them are Weiyun John Kao and Glen Kwan. Engineered tissues fend off white blood cells Weiyuan John Kao’s research into tissue engineering is at a frontier in the scientific and medical worlds. Artificial skin jumpstarted this field and it will soon be commonly used in hospital procedures. istorically, systems to deliver drugs were called dosage forms. Their primary purpose was to “do no harm” to the drug. They helped with chemical stability and sometimes with bioavilability. By contrast, modern delivery systems are intended to accomplish very special functions for certain drugs in certain patient populations. Patients with vomiting, epilepsy, migraine headache, and breakthrough pain, for example, need quick relief. Nasal or pulmonary delivery can achieve high rapid blood levels for them. Alternatively, compliance is especially difficult for the elderly and patients with neurological diseases. They might be better served with relatively long-acting systems such as transdermals, oral extended release, and prolonged release injectables. The field is growing fast. Currently special purpose drug delivery products account for $40 billion of the $300 billion world-wide pharmaceuticals market (about 13%). Within five years the market share will be more than 20%. Oral methods account for more than half of US drug delivery sales; inhalation more than a quarter; implants are 10%, and transdermals 8%. Economics are pushing drug delivery interest. Typically it costs less than $30 million and takes just 2-3 years to package an old drug in a new delivery system. New drug development, on the other hand, takes 17 years from discovery to market and costs over $750 million. Drug delivery – old and new. Bottom: three white blood cells (dark, reddish) bond with polymer (pale background). Other engineered artificial tissues, such as cartilage, are currently seeking FDA approval. The technology is advancing rapidly. Kao and his students are studying tissue engineering at the cellular level looking at how white blood cells react to biomaterial. The body’s reaction to foreign objects like donated organs, knee replacements, and dental implants is a major obstacle to their success. “If we understand the mechanisms of how cells interact with the material, then we can better design material that will be more biocompatible in the body,” says Kao. Kao’s work seeks to prevent white blood cells (WBC) from binding to the continued on page 2 1 MESSAGE FROM THE DEAN Targeting tomorrow Melvin Weinswig, RPh, PhD Dean “The School of Pharmacy at the University of Wisconsin-Madison will be recognized as the premier pharmacy school as judged by the quality of its education, research and service.” This vision statement was developed in a 1994 strategic planning session. We are now reviewing our vision and mission, and planning our course for the next decade in conjunction the University’s current strategic planning efforts. Given the overall success of the last five years, our new strategic plan needs to realign, not change, its target; it needs to take more precise aim. The new curriculum has been quite successful, though it needs some changes and modifications. The first class graduates in May 2001 and already many pharmacists say they are pleased with the products of this experience. One modification involves faculty establishing committees to assess students and the curriculum. Additionally, faculty continue to bring innovations to their teaching, using newer technology and distance education when appropriate. Research has always been a strength at the School. New faculty recruited to replace retirees will continue to keep Wisconsin in the forefront. In this issue, we feature the research of two of our newer faculty who have already distinguished themselves on campus. With our new facility and equipment, we have also improved the infrastructure for research. Faculty have brought their discoveries of research into the classroom and provide experience in research for students. We will continue to recruit and retain outstanding faculty that will keep us competitive with other universities and with industry. In the area of service, our faculty continue as leaders in national and international professional organizations as well as assisting in local and state endeavors. The students, who have all participated in community activities as part of the new curriculum, continue to return to these activities well after their course responsibility is over. The School of Pharmacy’s strategic planning will follow the University’s overall objectives. Tomorrow’s targets are to: • Promote research • Advance learning • Nurture human resources • Amplify the Wisconsin Idea • Accelerate globalization Many of you will be asked to assist us in our strategic plan. Thank you in advance for your help and cooperation. Innovative drug delivery systems are on the way (continued from page 1) molecules in these foreign objects by designing polymers with molecules that do not fit the human WBC receptors. By manipulating white blood cell behavior Kao hopes to reduce the severity of immune system response. This research also could have therapeutic applications in drug delivery, for wound healing, and in creating scaffolds for tissue engineered products. Kao came to the SOP in 1998 and has a joint appointment in the UW Biomedical Engineering Program. He did postdoctoral work in biomedical engineering in Zürich, Switzerland and at CalTech. Piggybacking drugs on “nano-size” polymers Glen Kwon is doing research in the merging the fields of polymer chemistry and drug delivery. One technique involves creating polymer micelles— minuscule particles about one billionth of a meter in diameter—to carry injectable drugs, particularly water insoluble anticancer and anti-fungal agents. Because they are so small the micelles can circulate freely in the blood, making it possible to effectively reach sites of disease in the body. Of course, introducing the drug into polymer micelles is a major challenge. Kwon and his team are currently exploring physical encapsulation and chemical bonding methods. Creating breast cancer vaccines is another strand of Kwon‘s research. Studies done with mice have shown successful breast cancer vaccination using polymer microspheres to activate the immune system. The microspheres are one millionth of a meter (10-6) in size and made of the same material as biodegradable sutures. “We are trying to present the breast cancer antigen to T-cells of the immune system,” says Kwon. “Once they are stimulated by the antigen in the microspheres, the hope is they will recognize and attack the breast cancer cells.” Kwon and his collaborator have been awarded a US Patent for this method of eliciting cellular immune responses with polymer microspheres. Kwon joined the SOP faculty in 1997. Previously he was an assistant professor at the Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Canada, and before that a postdoctoral fellow in Tokyo, Japan. The Wisconsin Pharmacy Graduate is published three times a year for all Pharmacy graduates by the University of Wisconsin–Madison School of Pharmacy Alumni Association. Visit our website: www. pharmacy.wisc. edu/alumni Send comments, address changes or membership information to: Paul Rosowski, RPh, MS UW–Madison School of Pharmacy 425 N. Charter Street, Room 1336 Madison, WI 53706-1515 Phone: 608/262-3717 E-mail: pgrosowski@pharmacy.wisc.edu Executive Committee Don Bartig, RPh, President Pat Vandehey, RPh, President-elect Russell J. Jensen, Treasurer Paul Rosowski, Secretary Richard Krumbiegel, Secretary Emeritus Melvin H. Weinswig, Dean John Boray, Director Paul Pisarzewicz, Director Pamela Ploetz, RPh, Director Claire M. Sedushak, Director Kenneth R. Schaefer, Director Produced by Lynn Entine, Entine & Associates, editor Susan Kummer, Artifax, graphic design 2 SECRETARY’S CAPSULES Psst! Come take a look Paul G. Rosowski, RPh, MS Secretary, PAA Scenes from Reunion 2000 In my spare time, I enjoy running on the Lakeshore path along the north side of campus. In making this trek, I pass by some historic points in the Wisconsin School of Pharmacy’s evolution. One of the first is South Hall. Built originally as a dormitory, it became the School’s first home in 1883. A second is North Hall which housed the School until 1901. A third is the Chemical Building, frequently remodeled over the years to become Chamberlin Hall where the School stands today. But perhaps the most notable point on my journey is the building site of the new School of Pharmacy, Rennebohm Hall. Since the summer of 1998 I have been amazed to watch the building’s structure evolve and become a reality. Completion of this facility will be a monumental moment in the School’s history: the first time we will have our own new home versus having to inhabit a structure that was designed for others. Leaving Chamberlin Hall will evoke many fond memories of the time I spent there. I certainly will cherish these times and hope they will not be forgotten. In all honesty, though, I more eagerly await the new memories that will be created in this new, premier facility. So do our faculty, staff, and students, all of whom will benefit from this change. Many alumni have not been as fortunate as I in seeing this evolution directly take place. With the aid of technology, though, you can observe its evolution virtually at the following Web location: www.pharmacy. wisc.edu/alumni. The presentation depicts the School’s rich history along with Rennebohm Hall’s construction. Seeing this presentation, I hope you will appreciate, as I have done, the great strides made over the past century. And remember, there is still time to purchase a Legacy Brick for you or someone special in your life to commemorate this new era in Wisconsin Pharmacy. — Paul Top: Citation recipient Gordon Flynn (’65), center, with his wife Beverly and Dean Weinswig. In the box is an antique balance Flynn saved from being discarded when he was a student. Now restored, it will be displayed in Rennebohm Hall. Left: Prof. George Zografi, Gordon Flynn, and William Tillman (’60) Below: Familiar faces include Gerald (’50) and Shirley (’50) Miller joining to sing “Varsity.” Don’t miss the next Reunion Weekend October 5-6, 2001 Mark your calendar today! Future PAA reunions All alumni invited Classes of Reunion ’51, ’61, ’76, ’86, ’91, ’96 ’52, ’62, ’77, ’87, ’97 ’53, ’63, ’78, ’88, ’98 2001 2002 2003 Bobbie and Bob Hammel (’48, ’56, ’59) with Dave Forbes (center) and Dick Forbes (right). Lenore Zeeh (‘36) with Bob Hammel (right). 3 Forbes named Alumnus of the Year David S. Forbes (’68, MS ’71, PhD ’73) was named Pharmacy Alumnus of the Year at Reunion Weekend in September. Forbes is Dean and Professor of Pharmacy at the University of Montana School of Pharmacy and Allied Health Sciences in Missoula, Montana. Dean Forbes has led the pharmacy school from the brink of disaster to a vital teaching and research program. In addition, a major renovation and expansion of the pharmacy building was just completed under his management. The National Pharmacy Accreditation Board was not happy with U-Montana’s program when Forbes took over in 1988. The school was in published probation status, primarily because of its limited faculty. “Fortunately, the legislature took notice and gave us some resources,” says Forbes. “That gave us a chance to fight for ourselves.” It was a tough battle. The university was thinking of eliminating the Pharmacy program. With seed money to expand the faculty base, the school began working hard to bring in grants and develop private support. Today it ranks 28th out of 82 pharmacy schools in federal funding. Private support has also grown. Contributors gave $8.4 million toward the $10.4 million cost of renovating their building. The school also just received nearly $700,000 from the Murdock Charitable Trust to buy sophisticated research equipment. But teaching is primary. “Our major strength is educating young men and women to practice pharmacy,” says Forbes. Recruiting and retaining Native American students into pharmacy, one of Forbes’ career goals, is now achieving success. Currently there are 13 Native American students among the Montana Pharmacy School’s 220 entry level students which just about mirrors the group’s representation in the state (6% of the population) and meets the University-wide goal. “We found that their science training is poor, so we bring them into the university in the summer time and teach them the courses they need for professional work,” says Forbes. “We don’t make special exceptions for them to get in, but we do our best to support them.” More importantly, the campus visits open young eyes to a world of possibilities beyond the tiny communities they come from. Forbes understands personally. He comes from the tiny Wisconsin town of Elroy. (Future governor Tommy Thompson graduated from high school a few years ahead of him.) He credits summer jobs working in asphalt paving with starting him on his career path. “Working for a blacktop company in the summer makes you want to go to college, and soon,” he says. UW Pharmacy Prof. Bob Hammel nudged Forbes into graduate school where he earned a PhD in Pharmacy Administration with a minor in Law. His UW training has served him well, Forbes says, especially the emphasis on a strong science base for health professional education. Innovations learned as a student at Wisconsin are concepts that still work well in states like Montana which have lagged behind, he says. In addition to his administrative career at Montana, Forbes was on the faculty of Pharmacy Practice at North Dakota State University from 1973 to 1988, serving as department chairman in his last year there. He is also a charter member of the American Society for Pharmacy Law, and a member of the Academy of Pharmaceutical Sciences, the American Assoc. of Colleges of Pharmacy, and the American Institute of the History of David S. Forbes (’68, MS ’71, PhD ’73) accepts Alumnus of the Year plaque from PAA Secretary Paul Rosowski. Pharmacy. His long career has been distinguished by numerous awards, service, and scholarship. An avid golfer and hiker, Forbes loves to ride horses on his six-acre ranch near Missoula. When he has time, he helps move cattle herds on a friend’s ranch. He’s grateful that last summer’s wildfires kept their distance from both his home and the campus. Eight members of the Class of 1950 came to Reunion Weekend 2000 to celebrate 50 years in Pharmacy: Robert Lewis, Norman Godfrey, Shirley Miller, Gerald Miller, Rueford Bork, George Drivas, Elmer Pire, and Roger Peterman. and friends at the Meet your fellow alumni eception Alumni Rhors d’oeuvres s Cash bar and alth-System American Society of He SHP) Pharmacists (A Nevada esars Palace, Las Vegas, Ca 2000 December 3, 6:00-9:00 p.m. cal Association American Pharmaceuti Convention (APHA) Annual a San Francisco, Californi 2001 March 19, 5:30–7:00 p.m. ociation o Pharmacy Alumni Ass nsin UW School of Pharmacy rmacy Society of Wisco Department o Pha UW Hospital Pharmacy Sponsored by 4 Faculty Awards Joseph Wiederholt, professor of pharmacy administration, received the Distinguished Pharmacy Educator Award from the American Association of Colleges of Pharmacy. The award recognizes faculty who excel in teaching, research and public service. Professor Wiederholt is the third School of Pharmacy faculty member to receive AACP’s top award, joining Professors George Zografi and Kenneth Connors. This makes the UW School of Pharmacy the only pharmacy school in the nation to claim three winners of this award. Melvin Weinswig, dean of the School of Pharmacy, has received the 2000 Distinguished Service Award from the Pharmacy Society of Wisconsin which recognizes and honors a Wisconsin pharmacist who has made outstanding sustained contributions to the profession of Pharmacy and the state’s professional society of pharmacists. James DeMuth, professor in Extension Services in Pharmacy, received the William L. Blockstein Award of Merit from the Continuing Pharmaceutical Education Section of the American Association of Colleges of Pharmacy. The award recognizes achievements in providing quality continuing pharmaceutical education. Sandra G. Hoel, RPh, MS (’84), is a retail pharmacist with Neuhauser Pharmacy in Madison. She joins us this Fall as a Clinical Instructor for the pharmacotherapy laboratory courses. Hoel completed her BS degree in pharmacy at Purdue and a hospital pharmacy residency at UW Hospital and Clinics prior to receiving her MS in Hospital Pharmacy. Kathleen A. Skibinski, RPh, MS (’86, ’88), has joined Extension Services in Pharmacy as Clinical Assistant Professor, developing and implementing outreach and continuing education programs for practicing pharmacists. Skibinski, a consultant with The Enright Group, was previously Assistant Director of Pharmacy Services at UW Hospital and Clinics and Clinical Instructor in the School of Pharmacy. Preceptor of the Year Mike Flint The Wisconsin Pharmacy Internship Board selected Pharmacist John Michael Flint of Madison as Preceptor of the Year for 2000. A 1981 SOP graduate, Flint served his internship at Meadowood Pharmacy in Madison then joined Mallatt’s Pharmacy as a staff pharmacist, becoming an owner in the early 1990s. Flint was a founding member of the Independent Pharmacy Cooperative and became its first president in 1987. The cooperative was one of the first of its kind nationally helps independent pharmacies stay competitive by pooling their purchasing power. In the last five years, Mike and his staff have specialized in patient compliance by offering medication packaging and information. Understanding his patients’ needs, Flint wanted to improve their pharmaceutical care. Flint’s students and interns remark on this strong part of the Mallatt learning experience. “Mike notes both what and how the intern is learning. If they learn best visually, Mike picks up on that. He uses the pen and paper to help enhance the understanding as he delegates responsibilities or explains a new concept to the intern. The patient is first in his practice. People know he cares for them personally. I admire Mike and see him as a role model as I pursue my profession as a pharmacist.” Flint has served as a preceptor since 1993 and has an appointment as a Clinical Instructor for the School of Pharmacy. New Faculty Scott R. Rajski, PhD, was an American Cancer Society Postdoctoral Scholar in the Division of Chemistry and Chemical Engineering at the California Institute of Technology before joining the SOP faculty as an Assistant Professor in the Pharmaceutical Sciences Division this Fall. He received his PhD degree in bio-organic chemistry from Colorado State University in 1997. His research interests are in the area of small molecule-biomolecule interactions and how these mediate medicinally useful biological activities. Maureen M. Barr, PhD, joined our faculty as an Assistant Professor in the Pharmaceutical Sciences Division during the past Spring. She was formerly a Howard Hughes Medical Institute postdoctoral associate at the California Institute of Technology. She received her PhD in Genetics and Development from Columbia University in 1995. Her research interests are in behavioral genetics and neurobiology. Paul Rosowski (left) congratulates Mike Flint (’81), owner of Mallatt’s Pharmacy in Madison and founding member of the Independent Pharmacy Cooperative, who was named the 2000 Preceptor of the Year by the Pharmacy Internship Board. 5 PAA Scholarships really matter! “I cried when I opened the letter . . . My husband had been out of work for four months . . . It was a tremendous blessing, and a relief, to know that the tuition would be offset by the scholarship.” –— Renee White, ’02 Renee White came to UW School of Pharmacy after 10 years as a volunteer with a non-profit, interdenominational relief agency in the Bahamas and the US Virgin Islands. Training at Madison Area Technical college led to work as a Pharmacy Technician and inspired her choice of a pharmacy career. “Attending Pharmacy School has been challenging, but I feel that I have learned so much from the faculty and staff,” she says. “I am very grateful for the scholarship. Knowing that donors were investing in the quality of future pharmacists, I want to try my best.” Renee White “The PAA scholarship was special. It was nice to be recognized for doing a good job, especially since the curriculum was so challenging. It provided a lot of motivation for me to go on with my education.” — David Mott ’88 David Mott was in his 4th year of college in 1987 when he earned a PAA Scholarship. After graduating he interned with Tom McGreggor at Moreland Plaza Pharmacy in Waukesha who helped him decide to return for his PhD. Now an Assistant Professor of Pharmacy Administration at the School of Pharmacy, Mott is doing pharmacy manpower studies and researching differences in drug therapy choices for insured and uninsured patients. “As a student facing student loans, the $500 scholarship helped,” Mott says. “But it was more than the money. It think it was the acknowledgment that I was appreciated. Now being back here and seeing students receive the scholarships, I appreciate the Pharmacy Alumni Association a lot.” David Mott Order your Legacy Brick today Help make a big difference in a Pharmacy student’s life Legacy Bricks Unique memento gift Winter and the holidays. They are a time for remembrance, appreciation, and gift-giving. What more unique and lasting gift for yourself and the pharmacists in your life than a PAA Legacy Brick? What better way for School of Pharmacy graduates and their families to say thanks for the scholarship support that helped launch your career? Buying a brick benefits you twice. It commemorates outstanding graduates of the UW School of Pharmacy, and recognizes Pharmacy’s future leaders by supporting PAA scholarships. And, it’s tax deductible. Give a once-in-a-lifetime gift this holiday season—a permanent place in Rennebohm Hall’s Legacy Lane—to a special person in your pharmacy life: s promising intern s valued employee s cherished friend s esteemed mentor More than half the taxdeductible $100 brick price goes directly into the PAA’s scholarship endowment fund. A certificate suitable for presentation will be sent on request. Order by December 11, 2000 for delivery in time for Christmas. Yes, add my brick along the entrance walk at Rennebohm Hall. Cost: $100 for PAA members and $135 for non-members (includes one-year PAA membership). $100 is tax deductible. Proceeds support the PAA Scholarship Fund. Specs: 3 lines per brick, 14 characters per line maximum, including spaces. FIRST and LAST NAME ssssssssssssss 1 2 3 4 5 6 7 8 9 10 11 12 13 14 (leave a space between names) LAST NAME OR ADDITIONAL NAME ssssssssssssss 1 2 3 4 5 6 7 8 9 10 11 12 13 14 (use for long names or 2nd name) DEGREE(S); GRADUATION DATE(S) ssssssssssssss 1 2 3 4 5 6 7 8 9 10 11 12 13 14 TOTAL enclosed (payable to the Pharmacy Alumni Association) $ ___________________ s Please send certificate Send to: Pharmacy Alumni Association — Legacy Brick, UW School of Pharmacy, 425 N. Charter St., Rm. 1336, Madison, WI 53706-1515 Your name __________________________________________________________________ Class of ________________________________ Address ______________________________________________________________________________________________________________ City __________________________________________________________ State______________ Home telephone ( ) ____________________________________ Work telephone ( ZIP code __________________________ ) __________________________________ E-mail ________________________________________________________________________________________________________________ 2001 Study/Travel program in Kauai, Hawaii Pharmacists in the February 7-14 Study/Travel program will bask in the lush environs of Hawaii’s “Garden Isle” while brushing up on management of epilepsy, migraines, depression, and hypertension. Evidence-based medicine practice is also on the program. Program faculty are UW SOP and Dept. of Neurology Assoc. Prof. Barry E. Gidal, PharmD, and Prof. Stephen W. Durst, PharmD, BCPS, from Ferris State University College of Pharmacy. Participants satisfactorily completing all evaluation exercises can earn 16 hours of continuing pharmacy education credit. Kauai’s spectacular landscape, backdrop to dozens of movies, is full of contrasts: from the sugar cane fields and dense tropical foliage covering stunning peaks to desert-like Waimea Canyon––the Grand Canyon of Hawaii. It boasts the greatest number of beaches (40) per mile of coastline of all the Hawaiian Islands. The Hyatt Regency Resort & Spa on sunny Poipu Beach features lush landscaping, a freshwater lagoon, golf, tennis, snorkeling, spa amenities, and more. Culinary delights include fresh seafood, Italian cuisine, and lavish buffets. “This was our 6th trip,” says one past participant. “We have come to expect the best and have yet to be disappointed.” “The strength of this program is the relaxed teaching atmosphere, quality of the faculty and interaction with pharmacists from different practice sites,” says another participant. For detailed program information contact Prof. Alan Hanson, 608/262-2099. For travel/hotel details, call Burkhalter Travel (800/556-9286, ext. 250, 251, or 254). TA, dissertator and grad student awards Julie Ganther (’91 PhD ’99) received the 2000 Rennebohm PhD Dissertation Award. She was nominated by advisor David Kreling for her PhD thesis: “Prescription Drug Utilization: Moral Hazard, Adverse Selection and the Role of Consumer Medical Care Preferences.” A publication resulting from her thesis appeared in the prestigious journal Medical Decision Making. She is currently an Assistant Professor in the University of Iowa’s College of Pharmacy. Ganther was twice a past recipient of Rennebohm TA Awards. Jennifer Loertscher, who received the 2000 Zaman-Saroya Graduate Student Award for Excellence in Research and Scholarship, is an Environmental Toxicology graduate student advised by Lynn Allen-Hoffmann. The award provides $1,000 to support the student’s attendance at a national or international research meeting. Recipients of the 2000 Rennebohm Teaching Assistant Awards are Monica Adams, Ketan Amin, and Rick Cline. Adams started graduate work in Pharmaceutical Sciences in September 1998 and works with Glen Kwon. Adams, who has a BS in Chemistry (1998) from Augusta State College, taught in Drug Delivery Systems Labs I and II in Fall 1999 and Spring 2000. Amin, who completed a BS in Pharmacy (1993) at the University of North Carolina-Chapel Hill, joined our Pharmaceutics graduate program in September 1996. He is currently working with Timothy Heath. He also taught in the Drug Delivery Systems Labs last Fall and Spring. Cline completed his BS and MS in Pharmacy (1993) at Ohio State University then joined UW’s Social and Administrative Sciences in Pharmacy graduate program in September 1998. He is currently working with David Mott. He taught Psychosocial Aspects of Pharmacy last Fall and Pharmacists in the Health Care System last Spring. 8 Citations go to Flynn, Koeller and Schneider Gordon L. Flynn (PhD ’65) is worldrenowned for his research on transdermal delivery. He holds numerous US patents, has authored over 130 research articles and has presented his research nationally and internationally. He began his career in pharmacy research at Upjohn then joined the Pharmaceutics faculty at the University of Michigan College of Pharmacy in 1972. Flynn has been active in many professional organizations throughout his career. The APhA awarded him the Ebert Prize in 1973 and he was elected a Fellow of both the Academy of Pharmaceutical Sciences, and the American Association of Pharmaceutical Scientists. Jim M. Koeller’s (’77, MS ’79) career focus is on improving patient health and quality of life through human oncology research and training new researchers in the field. He is currently Co-Director of the Center for Pharmaceconomic Studies at the University of Texas at Austin and a clinical professor at the UT Health Science Center at San Antonio. Koeller is a Milwaukee native who completed residency and an MS in hospital pharmacy at UW. He continued at UW until 1984 as a clinical instructor in the Department of Medicine and as a Clinical Assistant Professor in the School of Pharmacy before going to Texas. Three outstanding Pharmacy alumni recognized with UW Citations are (l-r) Gordon Flynn, Jim Koeller, and Phillip Schneider. Dean Mel Weinswig is second from right. Koeller is active in professional organizations, advisory and editorial boards, a prolific author, and a frequent lecturer, nationally and internationally. The American Cancer Society named him Volunteer of the Year and awarded him the National Merit Award in 1992. Philip J. Schneider (’70) completed a residency and MS in hospital pharmacy at Ohio State University. He developed many innovative programs in acute care, ambulatory hospital pharmacy practice, and education while Associate Director of Ohio State University’s Pharmacy school and as a faculty member at the Medical Center. Currently Schneider directs the Latiolais Leadership Program at OSU’s College of Pharmacy. This program provides an international forum to address leadership development, management techniques, research, and guidelines related to the medication use process. Schneider is past-president of ASHP and is currently the first nonphysician president of the American Society for Enteral and Parenteral Nutrition. A prolific author and frequent lecturer, Schneider has received numerous awards, and was elected a Fellow of ASHP. New Lifetime Members Constance Austin ’80 Bonnie Bachenheimer ’91 Thomas Bull ’96 Deann Cushman ’87 Marcy Glisczinski ’98 PharmD ’98 James Gollin ’65 Patricia Herschleb ’78 Norman Malmon ’68 Heidi Mansour ’96 Gail Staub ’94 Wisconsin Rapids Buffalo Grove, IL Waukesha Oshkosh Jefferson Mequon De Forest Brown Deer Madison Oak Creek Don’t miss the next Reunion Weekend October 5-6, 2001 Mark your calendar today! Welcome to the new Lifetime Members who joined since March 1, 2000. Sharing a laugh at the Tailgate party are (left) PAA President Don Bartig (’68) and K. Don Lindsay (’55). 9 Scholarship recipients for 2000 The following School of Pharmacy students received scholarships and awards at a ceremony in September. The scholarships and awards are funded through annual gifts from individual members of the profession, professional pharmacy organizations, chain drug stores, and the pharmaceutical industry, or through endowments and trusts established with the University of Wisconsin Foundation. Mindy Adamec, Menomonee Falls Marleen Barta, Manitowoc Monica Waclawski, Grafton Gregory Aleckson, Whitewater Brent Anderegg, Blair Marleen Barta, Manitowoc Jennifer Bassett, Ashland Mern Keir Scholarship Mern Keir Scholarship Mern Keir Scholarship Mern Keir Scholarship University League Scholarship Roy Kuramoto Scholarship National Pharmacists Association Scholarship, Rite Aid Scholarship for Community Practice Mern Keir Scholarship Lillian I. and Ronald J. Goggin Scholarship Wal-Mart Scholarship Mern Keir Scholarship Roy Kuramoto Scholarship Joseph A. and Margaret B. Gitzen Scholarship Roy Kuramoto Scholarship Mern Keir Scholarship Mern Keir Scholarship Roy Kuramoto Scholarship Mabel Johnson Memorial Scholarship Jacob Rossbach Scholarship Mabel Johnson Memorial Scholarship, Longs Drug Stores Scholarship John Janis Apinis Scholarship Mern Keir Scholarship Phi Delta Chi Scholarship Mern Keir Scholarship Mern Keir Scholarship Minority Affairs Program in Pharmacy Scholarship Phi Delta Chi Scholarship Arthur H. & Margaret H. Uhl Memorial Scholarship Milwaukee Alumni Chapter of Alpha Zeta Omega Scholarship, Kristin Ann Wright Memorial Scholarship, Richard Scott Key Memorial Scholarship Lillian I. and Ronald J. Goggin Scholarship Mern Keir Scholarship Mabel Johnson Memorial Scholarship Mern Keir Scholarship Mern Keir Scholarship Cynthia Wu Wilcox Scholarship Mabel Johnson Memorial Scholarship Cynthia Zernzach, Oshkosh Deborah Thums, Mayville Noah Thurber, Wisconsin Rapids Kim Tram, Brooklyn Park, Minn. Lisa Walczak, Sturgeon Bay Heather Wallander, Sheboygan Barbara Seiler, Brookfield Nathan Rasmussen, Madison Amy Rieck, Elkhorn Cindy Schwartz, Cottage Grove Joshua Schwiesow, Milwaukee Nicole Northrop, Madison Nicholas Olson, New Berlin Kristina Orlikowski, Wausau Lara Pape Paul Paschke, Brown Deer Jill Patin, Milwaukee Brett Petta, Platteville RandieAnn Nagao, Honolulu, Hawaii Sara McClaine, Rice Lake Emily McIlheran, Rochester Mern Keir Scholarship Jean and Peter Hauper Scholarship, Patton Scholarship, Pharmacists Mutual Companies Award Mern Keir Scholarship Owen Healthcare Scholarship, Kmart Pharmacy Scholarship for Excellence in Community Pharmacy Sandra Chuk-Wah Yu Scholarship Roy Kuramoto Scholarship William L. Blockstein Memorial Scholarship Mern Keir Scholarship Trempealeau Walgreen Company Scholarship Mern Keir Scholarship Kappa Psi Scholarship Mabel Johnson Memorial Scholarship, Apple/Karabensh Scholarship Mern Keir Scholarship Mern Keir Scholarship Mern Keir Scholarship Pharmacists Society of Milwaukee County Scholarship Pharmacists Society of Milwaukee County Scholarship Pharmacists Society of Milwaukee County Scholarship Women’s International Pharmacy Scholarship Mern Keir Scholarship Mern Keir Scholarship Roy Kuramoto Scholarship Walgreen Company Scholarship Nat’l Assoc. of Chain Drug Stores Education Foundation Scholarship, Walgreen Company Scholarship Roy Kuramoto Scholarship Jacob Rossbach Scholarship Minority Affairs Program in Pharmacy Scholarship William L. Blockstein Memorial Scholarship Kenneth Karlen Memorial Scholarship, Jacob Rossbach Scholarship Mern Keir Scholarship Rose E. Mancuso Scholarship, Kappa Psi Scholarship Cynthia Wu Wilcox Scholarship Lida W. Shearer Scholarship Anne Mertz, Kewaskum Susannah Motl, Racine Gary Benton, Faribault, Minn. Daniel Bestul, Waupun Susan Blaser, Barron Jill Bombien, Franklin Nancy Brennan, Kenosha Melanie Buege, Columbus Jason Buenger, Middleton Maureen Byrne, Appleton Jeremiah Carolfi, Manitowoc Sophy Cherian, Bangalore, India O. Marcelline Chuckuemeka, Madison Angela Clayton, Oregon Sarah Courtney, Janesville Tamara Sobaski, Cottage Grove, Minn. Mern Keir Scholarship Sarah Sobotkiewicz, Greenfield Sheri Sparks, Land O’Lakes Anthony Steeno, Neenah Emily Stevens, Marinette Kathleen Taylor, Madison Alison Tennie, Appleton Monica Thiry, Casco Ryan Davis, Aberdeen, S. Dakota Wendy Derksen, Brandon Joshua DeSilvey, Green Bay Sarah Dobbratz, Rothschild Lindsay Dunnum, Colgate Rachel Gonzalez, Milwaukee Bethanne Held, Waukesha Stephen Herbst, Burlington Jean Hetzel, South Milwaukee Curt Jacoby, Fredonia Melissa Killen, Marinette Amy Koivisto, Hurley Marni Koob, Rice Lake Amy Kuker, Madison Yuen Lai, Perak, Malaysia Catherine Marsh, Boulder Junction Angie Wedig, Darlington Rebecca Williams, Downers Grove, Ill. Ye Yang, Sheboygan 10 PAA Scholars The following Pharmacy students received $1000 Pharmacy Alumni Association Scholarships at a ceremony in September. Funds for these awards come from donations by Pharmacy Alumni and friends. The number and size of PAA scholarships have grown steadily thanks to your generosity. Joshua Bauer, Mayville Angela Brunner, Chetek (also Pharmacists Mutual Companies Scholarship) Elizabeth Buchman, Marinette Amy Christenson, Madison Sarah Fictum, Mishicot Kristine Grindle, Stoughton (also Ahlgrimm Scholarship) Heather Hellwig, Madison Troy Kienzle, West Allis Richard Kujak, LaCrosse Jill Lemke, Marshall Wylie Lom, Seymour Jessica McDowell, Moorhead, MN Marvin Moore, Rosendale Erin Narus, Fairbanks, AK Darcy Remker, Hayward Jill Rositch, Edgerton (also University League– Rosa P. Fred Memorial Scholarship) Dana Stieber, Wausau Sylvia Thomley, River Falls (also Donna Mirkes Memorial Scholarship and Shopko Pharmacists Scholarship) Todd Voss, Fond du Lac Benjamin Weitzel, Racine (also Albertson’s Inc./ Jewel-Osco Drug Stores Scholarship Jennifer Werner, Baraboo (also Pamela Ploetz Scholarship, Lillian I. and Ronald J. Goggin Scholarship) Renee White, Madison LeAnn Wiederhold, Muskego F Send us your news, your views, and your dues any time. The PAA, the Pharmacy Graduate, and the School of Pharmacy would like to hear from you! Fill in this form and mail to: Pharmacy Alumni Association Room 1336 425 N. Charter Street Madison, WI 53706-1515 fax: 608/262-3397 e-mail: pgrosowski@ pharmacy.wisc.edu R O M R E A D E R S My news or views to share __________________________________________________________________________________________ _____________________________________________________________________________________________________________________ Please send me information on ______________________________________________________________________________________ s Here are my annual PAA membership dues ($35) s Make me a lifetime PAA member ($200) (Make check* payable to the UW Pharmacy Alumni Association) s Here is my tax deductible contribution to the PAA Scholarship Fund (Make check* payable to the UW–Foundation–PAA) *Separate checks, please, to ensure tax deductibility. Name ______________________________________________________________________________________________________________ UW graduation year B.S. ________________ M.S.______________________ PharmD ________________ Ph.D. ____________________ s E-mail address ___________________________________________________________ s Please change my mailing address to: Street ________________________________________________________________________________________________________________ City____________________________________________________________ State _______________ Zip _____________________________ 11 Report from The Second Annual University of Wisconsin-Madison School of Pharmacy Pharmacy Alumni Association Continuing education opportunities Extension Services in Pharmacy offers a variety of continuing education opportunities. 2001 Travel Seminar February 7-14, 2001 Kauai, Hawaii Twenty-second Annual Winter Milwaukee Symposium Sunday January 21 Sheraton Milwaukee, Brookfield Twenty-second Annual Madison Clinical Conference March 21-22 Marriott Madison West Hotel Pharmacotherapy on CD-ROM General Information Cardiology Pharmacotherapy Immunology Pharmacotherapy Infectious Disease Pharmacotherapy For detailed course descriptions, visit our website: www.pharmacy.wisc.edu/esp For registration materials or other information, contact: Extension Services in Pharmacy, 425 N. Charter Street, Madison, WI 53706. Phone: 608/262-3130 Fax: 608/262-2431 Scholarship Golf Tournament The Second Annual Golf Outing was a great success. Congratulations to the winners: Women’s Division 1st Place – 81 Terry Audley Cindy Benning Lynne Dittman Pam Ploetz Men’s Division 1st Place – 66 Rich Egan Matt Mabie Brian McIlhone Mark Wilberg 2nd Place – 65 Paul Rosowski Patricia Vandehey Tim Vandehey Thanks to our sponsors: Red Level ($1000 or greater) Osco Drug/Albertsons Walmart Pharmacy Cardinal Distribution 2nd Place – 67 Kevin Graham Alan Hanson Tom Mikkleson Jim Summer Longest Drive Bobbie Riley Longest Drive Jason Sims White Level ($999-$500) UW-School of Pharmacy Social and Administrative Sciences Division (Betty Chewning, Dave Kreling, Dave Mott, Jeanine Mount, Bonnie Svarstad, and Joseph Wiederholt) Schwarz Pharma Aventis Pharmaceuticals Longest Putt Lynne Dittman Longest Putt Brian Purscell Closest to the Pin Karen Merrill Closest to the Pin Tim Gossens Mixed Division 1st Place – 64 Josh Gossens Sandy Gossens Tim Gossens Jason Sims Black Level ($499-250) Burkhalter Travel Dermik Laboratories Marshland Pharmacies 12 Address correction requested UW–Madison School of Pharmacy Pharmacy Alumni Association 425 N. Charter Street, Rm. 1336 Madison, WI 53706-1515 Nonprofit Organization U.S. Postage PAID Madison, Wisconsin Permit No. 2165