Respiratory

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Respiratory Powered By Docstoc
					                     2004-2005
                  Respiratory Review




4 February 2013
    4:14 AM
          Abacavir


         Antiretroviral

Nucleoside reverse transcriptase
        inhibitor (NRTI)
    Acebutolol

     Sympatholytic
1 adrenergic antagonist
Class II antiarrhythmic

   Antihypertensive
     Antianginal
  Bronchoconstrictor
       Albuterol


     Sympathomimetic
   2 adrenergic agonist

Short acting bronchodilator
      Used in asthma
             Amikacin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

             30S ribosome
           Freezes initiation
         Aminoglycosides


               Antibiotics
Bactericidal protein synthesis inhibitors

             30S ribosome
            Freeze initiation
    Aminophylline


      Bronchodilator

     Methylxanthine
Phosphodiesterase inhibitor
     Used in asthma
          Amoxicillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor
               Antiulcer

          Amino penicillin
Inhibits peptidoglycan cross-linking
          Amphotericin B


                Antifungal
            Polyene antibiotic

Binds to ergosterol and alters permeability
                 Systemic
           Ampicillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

          Amino penicillin
Inhibits peptidoglycan cross-linking
      Atenolol

     Sympatholytic
1 adrenergic antagonist

   Antihypertensive
    Antiarrhythmic
      Antianginal
  Bronchoconstrictor
           Azithromycin


          Macrolide antibiotic
Bacteriostatic protein synthesis inhibitor

              50S ribosome
          Inhibits translocation
    Aztreonam


New  lactam antibiotic

     Monobactam
       Bacitracin


          Antibiotic
Cell wall synthesis inhibitor

  Topical, not a  lactam,
Inhibits dephosphorylation of
         bactoprenol
  Beclomethasone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
          Inhaled
  Benzathine penicillin G


         Penicillin antibiotic
    Cell wall synthesis inhibitor

Inhibits peptidoglycan cross-linking
       Repository preparation
  Betamethasone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
    Not by inhalation
     Betaxolol


     Sympatholytic
1 adrenergic antagonist

   Antihypertensive
 Glaucoma medication
  Bronchoconstrictor
        Bethanecol


        Cholinomimetic

       Muscarinic agonist
Induces defecation and urination
      Bronchoconstrictor
   Biltolterol


  Sympathomimetic
2 adrenergic agonist

   Bronchodilator
    Bispropolol


    Sympatholytic
 adrenergic antagonist

   Antihypertensive
  Bronchoconstrictor
     Budesonide


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
          Inhaled
       Captopril


     Antihypertensive

Converting enzyme inhibitor
 Heart failure treatment
   Angioedema producer
         Carbenicillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

    Anti-pseudomonal penicillin
Inhibits peptidoglycan cross-linking
     Carteolol


    Sympatholytic
 adrenergic antagonist

   Antihypertensive
  Bronchoconstrictor
        Caspofungin


    Echinocandin antifungal

   Blocks synthesis of fungal
 (1,3)-d-glucan in the cell wall
        Cefaclor


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       2nd generation
            Oral
       Cefadroxil


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       1st generation
            Oral
       Cefepime


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

      4th generation
     CSF penetration
      Cefotaxime


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

      3rd generation
     CSF penetration
       Cefoxitin


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       2nd generation
     Ceftazidime


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       3rd generation
     Ceftriaxone


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

      3rd generation
     CSF penetration
      Cefuroxime


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

      2nd generation
     CSF penetration
      Cephalexin


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       1st generation
            Oral
        Cephalosporins


             Antibiotics
               lactam

    Cell wall synthesis inhibitors
Inhibit cross-linking of peptidoglycan
      Cephalothin


  Cephalosporin antibiotic
Cell wall synthesis inhibitor

       1st generation
            Oral
Cetirizine


Antihistamine

H1 antagonist
Non-sedating
         Chloramphenicol


                Antibiotic
Bacteriostatic protein synthesis inhibitor

             50S ribosome
    Inhibits peptide bond formation
Chlorpheniramine


Classical antihistamine

    H1 antagonist
      Ciprofloxacin


  Fluoroquinolone antibiotic
  DNA replication inhibitor

Inhibits bacterial DNA gyrase
           Clarithromycin


          Macrolide antibiotic
Bacteriostatic protein synthesis inhibitor
                Antiulcer

              50S ribosome
          Inhibits translocation
    Clavulanic acid


   -lactamase inhibitor

Combined with antibacterials
             Clindamycin


                Antibiotic
Bacteriostatic protein synthesis inhibitor

             50S ribosome
          Anaerobic infections
         Clotrimazole


        Imidazole antifungal

  Inhibits synthesis of ergosterol
Lanosterol 14a demethylase inhibitor
           Cloxacillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

  Penicillinase resistant penicillin
Inhibits peptidoglycan cross-linking
Cortisol (Hydrocortisone)


    Adrenocorticosteroid
       Glucocorticoid

 Anti-inflammatory steroid
    Cromolyn sodium


      Mast cell stabilizer

      Inhibits release of
     mast cell mediators
Used prophylactically in asthma
          Cycloserine


              Antibiotic
    Cell wall synthesis inhibitor

         Secondary TB drug
Inhibits formation of Park nucleotide
            Dapsone


        Sulfone antibiotic
         Nucleic acid and
    protein synthesis inhibitor

Inhibits dihydropteroate synthetase
              Leprosy
          Delavirdine


           Antiretroviral

Non-nucleoside reverse transcriptase
         inhibitor (NNRTI)
  Dexamethasone


  Adrenocorticosteroid
     Glucocorticoid
     Antineoplastic

Anti-inflammatory steroid
    Not by inhalation
         Didanosine


         Antiretroviral

Nucleoside reverse transcriptase
        inhibitor (NRTI)
      Dideoxyinosine (ddI)
Diphenhydramine


Classical antihistamine
      Antiemetic

    H1 antagonist
            Doxycycline


         Tetracycline antibiotic
Bacteriostatic protein synthesis inhibitor

            30S ribosome
 Prevents aminoacyl tRNA attachment
 Ecothiophate


Anticholinesterase

    Vasodilator
Bronchoconstrictor
Glaucoma treatment
        Edrophonium


       Anticholinesterase

           Vasodilator
Diagnostic for myaesthenia gravis
       Bronchoconstrictor
         Efavirenz


        Antiretroviral

    Non-nucleoside reverse
transcriptase inhibitor (NNRTI)
       Enalapril


     Antihypertensive

Converting enzyme inhibitor
   Angioedema producer
Enfuvirtide (T-20)


    Antiretroviral

   Fusion inhibitor
     Ephedrine


Indirect sympathomimetic

    Vasoconstrictor
    Bronchodilator
     Decongestant
     Epinephrine


    Sympathomimetic
a and  adrenergic agonist

     Vasoconstrictor
     Bronchodilator
           Erythromycin


          Macrolide antibiotic
Bacteriostatic protein synthesis inhibitor

              50S ribosome
          Inhibits translocation
       Esmolol


      Sympatholytic
1 adrenergic antagonist
 Class II Antiarrhythmic

   Antihypertensive
  Bronchoconstrictor
      Ethambutol


        Antibiotic

Major drug for tuberculosis
       Ethionamide


          Antibiotic

Secondary drug for tuberculosis
Fexofenadine


 Antihistamine

 H1 antagonist
 Non-sedating
          Fluconazole


         Triazole antifungal

  Inhibits synthesis of ergosterol by
inhibiting lanosterol 14a demethylase
          Flucytosine


            Antifungal

Converted by fungi to 5-fluorouracil
  faulty RNA and DNA synthesis
     Flunisolide


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
          Inhaled
Fluorinated Quinolones
     ciprofloxacin, norfloxacin




       Antibiotics
 DNA replication inhibitors

Inhibit bacterial DNA gyrase
     Fluticasone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
          Inhaled
     Formoterol


    Sympathomimetic
  2 adrenergic agonist

Long acting bronchodilator
            Gentamicin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

            30S ribosome
           Freezes initiation
  Griseofulvin


     Antifungal

Binds to microtubules
  Hydrocortisone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
  Hydroxyzine


Classical antihistamine

    H1 antagonist
   Imipenem/Cilastatin


     New  lactam antibiotic

        Cilastatin inhibits a
kidney dipeptidase that inactivates
              imipenem
     Indinavir


    Antiretroviral

Protease inhibitor (PI)
   Ipratropium


   Anticholinergic

    Antimuscarinic
Inhaled bronchodilator
  Isoetharine


 Sympathomimetic
 adrenergic agonist

  Bronchodilator
            Isoniazid


              Antibiotic

Inhibits biosynthesis of mycolic acids
     Major drug for tuberculosis
Isoproterenol


 Sympathomimetic
 adrenergic agonist

   Vasodilator
  Bronchodilator
         Itraconazole


         Triazole antifungal

  Inhibits synthesis of ergosterol by
inhibiting lanosterol 14a demethylase
         Ketoconazole


        Imidazole antifungal

  Inhibits synthesis of ergosterol by
inhibiting lanosterol 14a demethylase
        Lamivudine


         Antiretroviral

Nucleoside reverse transcriptase
        inhibitor (NRTI)
    Levobunolol


    Sympatholytic
 adrenergic antagonist

   Antihypertensive
  Bronchoconstrictor
       Linezolid


 Oxazolidinone antibiotic
Protein synthesis inhibitor

  50S ribosomal subunit
       Lisinopril


     Antihypertensive

Converting enzyme inhibitor
 Heart failure treatment
   Angioedema producer
Loratidine


Antihistamine

H1 antagonist
Non-sedating
               Macrolides
    erythromycin, azithromycin, clarithromycin




                Antibiotics
Bacteriostatic protein synthesis inhibitors

                50S ribosome
  Malathion


Anticholinesterase

   Vasodilator
Bronchoconstrictor
Metaproterenol


  Sympathomimetic
2 adrenergic agonist

  Bronchodilator
  Used in asthma
          Methicillin


        Penicillin antibiotic
   Cell wall synthesis inhibitor

  Pencillinase resistant penicillin
Inhibits peptidoglycan cross-linking
Methylprednisolone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
    Not by inhalation
   Metipranolol


    Sympatholytic
 adrenergic antagonist

  Bronchoconstrictor
     Metoprolol


     Sympatholytic
1 adrenergic antagonist

   Antihypertensive
Heart failure medication
  Bronchoconstrictor
      Metronidazole

          Antibiotic
         Antiparasitic
          Antiulcer

           Anaerobes
Reduction leads to intermediates
       that damage DNA
           Miconazole


        Imidazole antifungal

  Inhibits synthesis of ergosterol by
inhibiting lanosterol 14a demethylase
             Minocycline


         Tetracycline antibiotic
Bacteriostatic protein synthesis inhibitor

            30S ribosome
 Prevents aminoacyl tRNA attachment
    Montelukast


  Leukotriene inhibitor

LTR1 and LTD4 antagonist
   Asthma treatment
            Nafcillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

  Penicillinase resistant penicillin
Inhibits peptidoglycan cross-linking
        Nedocromil


      Mast cell stabilizer

 Inhibits release of mast cell
           mediators
Used prophylactically in asthma
            Neomycin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

             30S ribosome
           Freezes initiation
                Topical
        Neostigmine


       Anticholinesterase

          Vasodilator
Treatment for myaesthenia gravis
Promotes defecation and urination
       Bronchoconstrictor
             Netilmicin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

             30S ribosome
           Freezes initiation
           Nevirapine


           Antiretroviral

Non-nucleoside reverse transcriptase
         inhibitor (NNRTI)
      Norfloxacin


  Fluoroquinolone antibiotic
  DNA replication inhibitor

Inhibits bacterial DNA gyrase
              Nystatin


               Antifungal
           Polyene antibiotic

Binds to ergosterol & alters permeability
                 Topical
            Oxacillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

  Pencillinase resistant penicillin
Inhibits peptidoglycan cross-linking
          Oxytetracycline


         Tetracycline antibiotic
Bacteriostatic protein synthesis inhibitor

            30S ribosome
 Prevents aminoacyl tRNA attachment
 Para-aminosalicylic acid


            Antibiotic
         Nucleic acid and
    protein synthesis inhibitor

Inhibits dihydropteroate synthetase
         Secondary TB drug
    Penbutolol


    Sympatholytic
 adrenergic antagonist

   Antihypertensive
  Bronchoconstrictor
            Penicillins


          lactam antibiotics
    Cell wall synthesis inhibitors

Inhibit cross-linking of peptidoglycan
          Penicillin G


         Penicillin antibiotic
    Cell wall synthesis inhibitor

            Acid labile
Inhibits peptidoglycan cross-linking
           Penicillin V


         Penicillin antibiotic
    Cell wall synthesis inhibitor

More acid resistant than Penicillin G
Inhibits peptidoglycan cross-linking
 Phenylephrine


  Sympathomimetic
a1 adrenergic agonist

 Vasoconstrictor
Nasal decongestant
Phenylpropanolamine


Indirect sympathomimetic

  Nasal decongestant
 Removed from market*
    (may be in medicine cabinets!)
Physostigmine


Anticholinesterase

   Bradycardic
   Vasodilator
Bronchoconstrictor
  Pilocarpine


  Cholinomimetic

Muscarinic agonist
   Antiglaucoma
Bronchoconstrictor
      Pindolol


    Sympatholytic
 adrenergic antagonist

   Antihypertensive
  Bronchoconstrictor
          Piperacillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

    Anti-pseudomonal penicillin
Inhibits peptidoglycan cross-linking
   Pirbuterol


  Sympathomimetic
2 adrenergic agonist

   Bronchodilator
          Polymyxin B


             Antibiotic
Disrupts gram negative cell membrane

   Binds phosphatidylethanolamine
            Bactericidal
   Prednisone


Adrenocorticosteroid
   Glucocorticoid
   Antineoplastic

 Anti-inflammatory
 Not by inhalation
      Probenecid


         Uricosuric

Adjunct in penicillin therapy
    Procaine Penicillin G


         Penicillin antibiotic
    Cell wall synthesis inhibitor

       Repository preparation
Inhibits peptidoglycan cross-linking
  Promethazine


Classical antihistamine
    Antipsychotic
      Antiemetic

    H1 antagonist
    Propranolol


    Sympatholytic
 adrenergic antagonist
Class II antiarrhythmic

   Antihypertensive
  Bronchoconstrictor
  Pseudoephedrine


    Sympathomimetic
a and  adrenergic agonist

    Vasoconstrictor
   Nasal decongestant
    Pyrazinamide


        Antibiotic

Major drug for tuberculosis
      Pyridostigmine


       Anticholinesterase

          Vasodilator
Treatment for myaesthenia gravis
      Bronchoconstrictor
Quinopristin/Dalfopristin


   Streptogramin antibiotic
  Protein synthesis inhibitor

    50S ribosomal subunit
          Rifampin

           Antibiotic
Nucleic acid synthesis inhibitor

Inhibits DNA dependent RNA
         polymerase
     Major drug for TB
     Ritonavir


    Antiretroviral

Protease inhibitor (PI)
     Salmeterol


    Sympathomimetic
  2 adrenergic agonist

Long acting bronchodilator
    Saquinavir


    Antiretroviral

Protease inhibitor (PI)
     Silver sulfadiazine

      Sulfonamide antibiotic
      Microbial nucleic acid
  and protein synthesis inhibitor

Inhibits dihydropteroate synthetase
               Topical
           Spectinomycin


                Antibiotic
Bacteriostatic protein synthesis inhibitor

              30S ribosome
          Streptomycin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

             30S ribosome
           Freezes initiation
   Succinylcholine


        Paralytic

   Depolarizing blocker
Paralyzes skeletal muscles
   Bronchoconstrictor
        Sulfacetamide


      Sulfonamide antibiotic
      Microbial nucleic acid
  and protein synthesis inhibitor

Inhibits dihydropteroate synthetase
               Topical
          Sulfadoxine


       Sulfonamide antibiotic
       Microbial nucleic acid
   and protein synthesis inhibitor

Dihydropteroate synthetase inhibitor
     Sulfamethoxazole


      Sulfonamide antibiotic
      Microbial nucleic acid
  and protein synthesis inhibitor

Inhibits dihydropteroate synthetase
        Sulfisoxazole


      Sulfonamide antibiotic
         Nucleic acid and
    protein synthesis inhibitor

Inhibits dihydropteroate synthetase
        Sulfonamides


           Antibiotics
        Nucleic acid and
   protein synthesis inhibitors

Inhibit dihydropteroate synthetase
        Terbinafine


     Allylamine antifungal

Inhibits ergosterol synthesis by
  inhibiting squalene epoxidase
     Terbutaline


     Sympathomimetic
   2 adrenergic agonist

Short acting bronchodilator
         Tocolytic
     Uterine relaxant
            Tetracycline


                Antibiotic
Bacteriostatic protein synthesis inhibitor
                 Antiulcer

            30S ribosome
 Prevents aminoacyl tRNA attachment
     Theophylline


      Bronchodilator

     Methylxanthine
Phosphodiesterase inhibitor
     Used in asthma
           Ticarcillin


         Penicillin antibiotic
    Cell wall synthesis inhibitor

    Anti-pseudomonal penicillin
Inhibits peptidoglycan cross-linking
      Timolol

    Sympatholytic
 adrenergic antagonist

  Antihypertensive
 Glaucoma treatment
     Anti-anginal
 Bronchoconstrictor
           Tobramycin


       Aminoglycoside antibiotic
Bactericidal protein synthesis inhibitor

             30S ribosome
           Freezes initiation
   Triamcinolone


  Adrenocorticosteroid
     Glucocorticoid

Anti-inflammatory steroid
          Inhaled
           Trimethoprim


                Antibiotic
         Protein and nucleic acid
            synthesis inhibitor

           Folic acid antagonist
Inhibits bacterial dihydrofolate reductase
 Tripelennamine


Classical antihistamine

    H1 antagonist
     Vancomycin


         Antibiotic
Inhibits cell wall synthesis


      Not a  lactam
          Voriconazole


         Triazole antifungal

  Inhibits synthesis of ergosterol by
inhibiting lanosterol 14a demethylase
    Zafirlukast


  Leukotriene inhibitor

LTR1 and LTD4 antagonist
   Asthma treatment
        Zalcitabine


         Antiretroviral

Nucleoside reverse transcriptase
        inhibitor (NRTI)
     Dideoxycytidine (ddC)
         Zidovudine
    Azidothymidine (AZT)
         Antiretroviral

Nucleoside reverse transcriptase
        inhibitor (NRTI)
      Zileuton


 Leukotriene inhibitor

5-lipoxygenase inhibitor
     Used in asthma

				
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