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                                                                                             Contents
                                Preface .......................................................................... vii

                                                                         I. BASIC PRINCIPLES
                            Introduction ................................................................ 1 .1
                        Pharmacodynamics .......................................................... 10 .9
                         Pharmacokinetics ........................................................... 20 .3
                        Drug Metabolism ............................................................ 32 .4
                   Drug Evaluation & Regulation ................................................. 39 .5

                                                            I1. AUTONOMIC DRUGS
         Introduction to Autonomic Pharmacology ....................................... 44 .6
 Cholinoceptor-Activating & Cholinesterase-lnhibiting Drugs ........................ 58 .7
   Cholinoceptor Blockers & Cholinesterase Regenerators ........................... 68 .2
                    Sympathomimetics .......................................................... 77 .2
                 Adrenoceptor Blockers ...................................................... 87 .11

                                                    II1. CARDIOVASCULAR DRUGS
                 Drugs Used in Hypertension .................................................. 98 .11
          Vasodilators & the Treatment of Angina ........................................ 109 .19
          Drugs Used in Congestive Heart Failure ........................................ 119 .13
                   Antiarrhythmic Drugs ....................................................... 130 .14
                     Diuretic Agents ............................................................ 143 .15
            IV. DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE
        Histamine, Serotonin, & the Ergot Alkaloids ..................................... 157 .16
                    Vasoactive Peptides ........................................................ 168 .17
                                                                                                       iii

                                                                             iv / CONTENTS
                                                                                                .VI
           Prostaglandins & Other Eicosanoids ........................................... 174 .12
           Nitric Oxide, Donors, & Inhibitors ............................................. 180 .12
      Bronchodilators & Other Drugs Used in Asthma ................................. 184 .91

               V. DRUGS THATACTIN THE CENTRAL NERVOUS SYSTEM
          Introduction to CNS Pharmacology ............................................ 195 .91
               Sedative-Hypnotic Drugs .................................................... 204 .99
                       Alcohols .................................................................. 212 .93
                  Antiseizure Drugs .......................................................... 219 .94
                  General Anesthetics ........................................................ 228 .95
                   Local Anesthetics .......................................................... 238 .96
               Skeletal Muscle Relaxants ................................................... 244 .97
Drugs Used in Parkinsonism & Other Movement Disorders ........................ 252 .92
            Antipsychotic Drugs & Lithium ............................................... 260 .92
                    Antidepressants ............................................................ 268 .31
           Opioid Analgesics & Antagonists ............................................. 278 .31
                    Drugs of Abuse ............................................................ 287 .39
    DRUGS WITH IMPORTANT ACTIONS ON BLOOD, INFLAMMATION, &
                                                                                            GOUT
  Agents Used in Anemias & Hematopoietic Growth Factors ........................ 296 .33
            Drugs Used in Coagulation Disorders .......................................... 304 .34
      Drugs Used in the Treatment of Hyperlipidemias ................................. 314 .35
 Nonsteroidal Anti-inflammatory Drugs, Acetaminophen, & Drugs Used in Gout .36
                                                                                         ....... 322

                                                              VII. ENDOCRINE DRUGS
             Hypothalamic & Pituitary Hormones ........................................... 331 .37
               Thyroid & Antithyroid Drugs .................................................. 336 .32
                Corticosteroids & Antagonists ................................................ 343 .32
              Gonadal Hormones & Inhibitors ............................................... 349 .41
  Pancreatic Hormones, Antidiabetic Agents, & Hyperglycemic Drugs ................ .41
                                                                                                  359
        Drugs That Affect Bone Mineral Homeostasis ................................... 368 .49


                                                                                       CONTENTS / v
                                                                                                        .VIII
                                                         CHEMOTHERAPEUTIC DRUGS
Beta-Lactam Antibiotics & Other Cell Wall Synthesis Inhibitors .................... 374 .43
     ,Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, Streptogramins .44
                            Linezolid ................................................................ 385 &
                      Aminoglycosides ........................................................... 394 .45
      Sulfonamides, Trimethoprim, & Fluoroquinolones ............................... 402 .46
                  Antimycobacterial Drugs .................................................... 411 .47
                     Antifungal Agents .......................................................... 419 .42
           Antiviral Chemotherapy & Prophylaxis ......................................... 427 .42
  Miscellaneous Antimicrobial Agents & Urinary Antiseptics ........................ 439 .51
               Clinical Use of Antimicrobials ................................................ 447 .51
       Basic Principles of Antiparasitic Chemotherapy ................................. 455 .59
                     Antiprotozoal Drugs ........................................................ 460 .53
                     Anthelmintic Drugs ......................................................... 468 .54
                   Cancer Chemotherapy ....................................................... 476 .55
                   Immunopharmacology ...................................................... 491 .56

                                                                                  IX. TOXICOLOGY
                    Introduction to Toxicology ................................................... 504 .57
                          Heavy Metals .............................................................. 510 .52
                 Management of the Poisoned Patient .......................................... 517 .52

                                                                          X. SPECIAL TOPICS
           Drugs Used in Gastrointestinal Disorders ...................................... 525 .61
                    Drug Interactions ........................................................... 530 .61
  Vaccines, Immune Globulins, & Other Complex Biologic Products .................. .69
                                                                                                     538
     Botanical Medications & Nutritional Supplements ................................ 542 .63
      Appendix I. Key Words for Key Drugs ................................................. 550
           Appendix II. Examination 1 .......................................................... 564
           Appendix II1. Examination 2 ......................................................... 584
Appendix IV. Strategies for Improving Test Performance ................................ 603
                                                                                              Index

				
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posted:1/26/2013
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