DERMATOLOGY by huangyuarong

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									DERMATOLOGY

Gerianne R. Bliss, M.D.
 Chuck Hensley, R.Ph.
           DERMATOLOGY
• Categories
  –   Acne preparations
  –   Anti-infectives and Combinations
  –   Antiprutitics/Anti-inflammatory Agents
  –   Antipsoriatic Agents
  –   Miscellaneous
           DERMATOLOGY
• ACNE
 – Accutane (Isotretinoin)
    • 10mg, 20mg, 40mg
    • Black box warning
       –   Not for females who may become pregnant
       –   Two neg pregnancy tests, repeat monthly
       –   Two forms of birth control
       –   Fill Rx within 7 days, no refills
       –   Max one month supply
    • Treatment of severe nodular acne
           DERMATOLOGY
• Accutane
  – Take with food
  – Avoid vitamin A, Alcohol, Tetracyclines, St. John’s
    wort
  – Check liver functions, lipids, blood sugar
  – Avoid if genetic history of osteoporosis
  – Can cause psychosis
  – WORKS GREAT FOR SELECTED PATIENTS
         DERMATOLOGY
ACNE
– ANTI-INFECTIVES
– Erthromycin
   • A/T/S, Benzamycin, Emgel, Erycette
– Keratolytic – Benzoyl peroxide
   • Benzac AC, Benzaclin, Benzamycin
– Retinoic Acid Derivative
   • Avita, Differen, Tazorac, Retin-A
– Metronidazole
   • Metrocream, Metrogel, Metrolotion
         DERMATOLOGY
• ACNE
 – ANTI-INFECTIVES - ORAL
    • Antibiotics – TCN, Clindamycin, Erythromycin
 – Oral Contraceptives
    • Ortho-Tricyclen, Estrostep Fe
           DERMATOLOGY
• ANTI-INFECTIVES
  – Scabicides
     • Acticin, Elimite, Kwell, Nix
  – Antifungals
     • Lamisil AT, Lotrimin AF, Lotrimin Ultra, Mentax, Monistat-
       Derm, Mycolog, Naftin, Nizoral A-D, Penlac
  – Antivirals
     • Abreva, Denavir, Zovirax Oint
  – Antiseborrheic
     • Selsun
             DERMATOLOGY
• Antipruritics/Anti-Inflammatory Agents
   – Steroids
      • Acclovate, Aristocort, Cyclocort, Dermatop,
        Diprolene/Diprosone, Elocon, Lidex
   – Macrolactam
      • Elidel Cream – tx of atopic dermatitis
   – Macrolide immunosuppressant
      • Protopic
   – H1/H2 receptor blocker
      • Zonalon
         DERMATOLOGY
• ANTIPSORIATIC AGENTS
 – Vit D3 derivative
    • Dovonex/Dovonex Scalp
 – Dihydrofolic reductase inhibitor
    • Methotrexate (rheumatrex)
 – Immunosuppressant
    • Neoral
 – Retionoic Acid Derivative
    • Tazorac
             DERMATOLOGY
• MISCELLANEOUS AGENTS
  – Aldara (imiquimod)
     •   Immune response modifier
     •   External genital and perianal warts
     •   AAA 3x/wk hs
     •   Max 16 wks
  – Condylox (podofilox)
     • External genital and perianal warts
     • AAA q 12 hrs/3days, off 4 days
     • Max 4 treatment cycles
          DERMATOLOGY
• Antimetabolites for actinic keratoses
  – Efudex, Fluoroplex
• Propecia (finasteride)
  – Treat male pattern baldness-for men only
• Renova (tretinoin)
  – Treat fine wrinkles
• Solaquin Forte
  – Depigmenting agent
            DERMATOLOGY
• Vaniqa (Eflornithine)
   – Decrease unwanted facial hair in women
• Bactroban (mupirocin)
   – Bacterial protein synthesis inhibitor
   – Treatment of impetigo due to S. aureus and Strep
     pyogenes
   – AAA tid
• Drysol
   – Aluminum chloride
   – Management of hyperhidrosis
   – AAA qhs, wash in am, when under control, 1-2x/wk

								
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