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nhmrc funded research into all viral hepatitis issues 2000 - 2012

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									NHMRC FUNDED RESEARCH INTO ALL VIRAL HEPATITIS ISSUES 2000 - 2012
             Type                     2000            2001            2002            2003            2004            2005            2006           2007            2008            2009            2010            2011              2012
     All Viral Hepatitis
                                  $2,011,775       $2,821,309      $2,444,439      $2,795,067      $2,486,650     $4,108,655      $6,082,295      $7,218,193     $7,943,971 $11,993,089 $10,595,521              $9,936,668       $10,524,050
     Research by CY
Report Run: 3 July 08/19 Mar 09/10 Mar 10/28 Feb 11/7 May 12
Sources: Extracted from NHMRC Databases -RGMS/ RMIS/GMS as at May 12

     All Viral Hepatitis            2000-01         2001-02         2002-03         2003-04         2004-05         2005-06         2006-07        2007-08         2008-09         2009-10         2010-11         2011-12           2012-13
      Research by FY              $2,416,546       $2,632,876      $2,619,757      $2,640,865      $3,297,658     $5,095,481      $6,650,248      $7,581,089     $9,968,534 $11,294,311 $10,266,097 $10,230,361                    $9,615,499
             Type                     2000            2001            2002            2003            2004            2005            2006           2007            2008            2009            2010            2011              2012
All Hepatitis B by CY               $523,050        $818,860        $765,251       $1,194,936       $816,003       $803,108        $952,671       $1,296,876     $1,913,199      $2,304,704      $1,769,947      $2,139,017        $2,639,800
All Hepatitis C by CY             $1,403,587       $2,009,494      $1,813,596      $1,730,463      $1,848,513     $3,445,377      $5,141,241      $5,926,971     $6,391,409 $10,502,599 $9,603,872               $8,827,015        $8,953,809
Note: Many grants address more than one disease/condition type and may be reported in more than one type. Therefore the total of each type is a discrete total and adding up all funding for the specific types will not equal the Total funding
row.

Methodology: NHMRC Research funding datasets rely entirely on the information provided by the Chief Investigators through the application process. Decisions on allocation to particular disease and health issue
datasets are made subjectively by the NHMRC Evaluation and Reporting Section (supported by other internal review mechanisms) based on the information provided. The key search parameters listed above form the
basis of the coverage of this dataset. Lay descriptions, where available have also been reviewed to support the allocation.
Keywords: Hepatitis, HEP, HBV, HCV
Grant Types:Includes all grant types except block funded institutes, IRIISS and equipment grants but in particular include all Hepatitis C grants
Fields of Research: Medical Virology
GMS Codes: Cat B - 026, Cat C - 565,570
GMS Admin Type: NH PH
GMS Budget Type: 4
GMS App ID range: 900000 - 009999
Status: Accepted, Approved, Payments can be made, Suspended, Terminated, Completed
Where: Start Year >= 2000
Pay Type: Calendar year budgets. Excludes claims. Excludes GST
Note: All figures shown are the cash amounts awarded to recipients in the calendar year
Data source: These data are sourced from the post 2009 Research Grants Management System (RGMS), pre 2000 NHMRC Grants Management Systems (GMS) and post 1999 NHMRC Research Management
Information Systems (RMIS) grants databases.
NHMRC FUNDED RESEARCH INTO ALL VIRAL HEPATITIS ISSUES 2000-2012
Keywords: Hepatitis (reviewed for viral Hepatitis), HEP, HEP A, HEP B, HEP C, HEP D, HEP E, HAV, HBV, HCV, HDV, HEV, HGV, GBV-C
Report Run: 3 July 08/19 Mar 09/10 Mar 10/28 Feb 11/7 May 12
Sources: Extracted from NHMRC Databases -RGMS/ RMIS/GMS as at May 12
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with the disease area of Viral Hepatitis (all
Hepatitis) through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the research area in
question may be either immediate or be a longer term perceived benefit. This dataset was current as at 7 May 12 but is subject to change over time.

Summary of Expenditure: All Viral Hepatitis
      2000           $2,011,775 Actual Expenditure               37 grants
      2001           $2,821,309 Actual Expenditure               40 grants       $14,000,000
      2002           $2,444,439 Actual Expenditure               33 grants
      2003           $2,795,067 Actual Expenditure               36 grants       $12,000,000
      2004           $2,486,650 Actual Expenditure               29 grants
      2005           $4,108,655 Actual Expenditure               36 grants       $10,000,000
      2006           $6,082,295 Actual Expenditure               42 grants
      2007           $7,218,193 Actual Expenditure               54 grants        $8,000,000
      2008           $7,943,971 Actual Expenditure               59 grants
      2009          $11,993,089 Actual Expenditure               58 grants        $6,000,000
      2010          $10,595,521 Actual Expenditure               52 grants
      2011           $9,936,668 Actual Expenditure               50 grants        $4,000,000
      2012          $10,524,050 Forecast Expenditure             53 grants
     Total          $80,961,682 As at Dec 12                                      $2,000,000
      2013           $8,706,953 Forward commitments              34 grants
      2014           $2,296,197 Forward commitments              17 grants                $0
      2015             $814,420 Forward commitments              6 grants                    2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
      2016             $106,526 Forward commitments              1 grant
      Total         $92,885,778 Incl out years
2 . Forward commitments funding data for out-years (ie beyond 2012) is subject to change when new grants are awarded in subsequent

 Grant Id        CIA Full Name                  Grant Type               Grant Subtype           Scientific Title         Simplified Title        Admin Institutution     State

   956084 Prof Ian Anderson           CARG                                                                            Developing a HIV and HepC for Reduction Program Koori in the M
                                                                                                                                                Victorian Aboriginal Health Service
                                                                                                                                                                           VIC
                                                                     ANCARD Project Grant Developing a HIV and HepC Risk Reduction ProgramRiskIDU in the Melbournefor IDUCommu
   967008 A/Pr Karen Vickery                                         Australian Clinical Research ECF B variation: a model of variation of molecular of variation of molecular epidemiology
                                      Early Career Fellowships (Australia)                    Hepatitis                                         University of Sydney
                                                                                                                      Hepatitis B variation: a model epidemiology          NSW
967448   Mr Ricardo Lareu                                        Dora                     Role of novel apoptosis-associated gene in tumour
                                  NHMRC Postgraduate Scholarships Lush Biomedical Scholarship                                                  University of Western Australia
                                                                                                                    Role of novel apoptosis-associated gene in tumour WA
977157   Dr George Marinos                                       Australian Clinical Research ECF
                                  Early Career Fellowships (Australia)                                              The chronic hepatitis c virus chronic New South Wales
                                                                                                                                               University of              NSW
                                                                                          The immunopathogenesis of immunopathogenesis of infectionhepatitis c virus infection
980194   A/Pr Allison Jilbert     NHMRC Project Grants                                                              Resolution of duck hepatitis
                                                                                                                                               University of Adelaide
                                                                 Standard Project Grant Mechanisms of resolution of hepadnavirus infection B virus infection              SA
981447   Prof Eric Gowans         NHMRC Project Grants                                                              Hepatitis C replication Royal Children's Hospital,QLD
                                                                 Standard Project Grant Molecular events of hepatitis C virusvirus replication                             Brisbane
981683   Prof Stephen Locarnini   NHMRC Project Grants                                                              Examination of minichromosome
                                                                                                                                               Melbourne Health
                                                                 Standard Project Grant Characterisation of the hepatitis B virus the key intermediate in the hepatitis VICB virus life cycle
983604   Prof Jill COCKBURN       SRDC                           Hepatitis C                                        An intervention to improve complianceNewcastle NSW
                                                                                                                                               University of with skin penetration g/lines in
                                                                                          An intervention to improve compliance with skin penetration g/lines in Tattooists, Beauty Ther
983608   Prof John Crofts         SRDC                           Hepatitis C                                        Peer counselling and testing service at a needle and syringe exchan
                                                                                                                                               M                          VIC
                                                                                          A pilot peer-based hepatitis Ctesting for Hepatitis C acfarlane Burnet Institute for Medical Res
983610   Prof John Crofts         SRDC                           Hepatitis C                                        HCV education and Vietnamese IDUs
                                                                                                                                               Macfarlane Burnet          VIC
                                                                                          Prevention of HCV infection amongst IDUs of Vietnamese ethnicity Institute for Medical Res
983615   Dr Alex Wodak            SRDC                           Hepatitis C                                        Encouraging drug administration (NIROA) amongWales
                                                                                                                                               University of New drug IDUsNSW
                                                                                          A feasibility study of non-injecting routes ofinjectors who cannot stopSouth use to shift to use b
983618   A/Pr Gary Dowsett        SRDC                           Hepatitis C                                        Gay men, drug culture and Hepatitis C prevention community
                                                                                                                                                drugs in University
                                                                                          Hepatitis C prevention among gay men who injectLa Trobe Melbourne's gayVIC
983619   A/Pr Michael Dunne       SRDC                           Hepatitis C                                        Quality of life chronic Hepatitis C withUniversity of QLD C_infection
                                                                                                                                               Queensland chronic Hepatitis
                                                                                          Quality of life among people living withamong people living infection           Technology
983627   Prof Sandra Gifford      SRDC                           Hepatitis C                                        The health and well beingDeakin University Hepatitis C
                                                                                                                                                 women living with        VIC
                                                                                          Identifying the social, personal and health needs ofof women living with Hepatitis C
983629   Prof Jeanette Ward       SRDC                           Hepatitis C                                         and their study of hepatitis C in generalWest Area NSW Services -
                                                                                                                                               Sydney South practice Health
                                                                                          National surveys of GPsA nationalpatients about needs, outcomes and patterns of care
983633   Prof Susan Kippax        SRDC                           Hepatitis C                                        IDU - Data collection. Transition to injecting South Wales
                                                                                                                                               University urban           NSW
                                                                                          Risks for Hepatitis C: Transition to injecting drug use among of Newand rural youth
983641   A/Pr Wendy Loxley        SRDC                           Hepatitis C                                        Exploring testing injectingCurtinusers for hepatitis and and other bloo
                                                                                                                                                drug University of Technology
                                                                                          Investigation of the process by which injecting drug users are tested for hepWA  C HIV/AIDS
983654   Dr Greg Rumbold          SRDC                           Hepatitis C                                        A national practices among C risk practices among injecting of risk
                                                                                                                                               Turning Point Alcohol andVIC Centre
                                                                                                                                                                           Drug
                                                                                          A national survey of hepatitis C risksurvey of hepatitisinjecting drug users: An overviewdrug u
983657   Prof Susan Sawyer        SRDC                           Hepatitis C                                        Reducing transmission ofMurdocha peer education VIC Institute
                                                                                                                                                HCV in Childrens Research
                                                                                          Reducing transmission of HCV in high risk young people - high-risk young people  strategy
987074   Dr A Dingley                                            CJ Martin (Biomedical) ECF molecular structure The molecular structure and delta virus ribozyme NSW virus riboz
                                  Early Career Fellowships (Overseas)                     The                                                  University of Sydney
                                                                                                                    and function of the Hepatitis function of the Hepatitis delta
990657   Prof Andrew Lloyd        CARG                                                                              Transmission and determinants of viral clearance in primary hepatitis
                                                                                                                                               University
                                                                 ANCARD Project Grant Modes of transmission, natural history and clearance of HCVof New South Wales       NSW
990988   Prof Stephen Locarnini   NHMRC Project Grants                                                              Investigations into the significance ofHealth resulting from B virus tre
                                                                                                                                               Melbourne virus            VIC
                                                                 Standard Project Grant Studies of polymerase/envelope protein variants of hepatitis Bchanges in hepatitis antiviralsel
991357   A/Pr Rohan Jayasuriya    CARG                                                                              Study of Risk Behaviour Users for transmission of NSW
                                                                                                                                               University Drug Users for transmission
                                                                 ANCARD Project Grant Cohort Study of Risk Behaviour in Injecting Drug in Injecting of WollongongHepatitis C of H
991502   Prof Eric Gowans         NHMRC Project Grants                                                              Hepatitis C and dendritic cells Children's Hospital, HCV
                                                                                                                                               Royal                       Brisbane
                                                                 Standard Project Grant Immunopathogenesis and immunotherapy associated with dendritic cells in QLD infection
997468   Dr Gerard MacQuillan     NHMRC Postgraduate Scholarships                         Mechanisms of response and non-response to interferon-alphaWestern interferon-alpha thera
                                                                 Medical Postgraduate Research Scholarship                                      and non-response to Australia
                                                                                                                                                                          WA
                                                                                                                    Mechanisms of response University of therapy (IFN-a) in chronic hep
997494   Dr Michael Sutherland    NHMRC Postgraduate Scholarships                         Characterisation of       Characterisation of the human cellular and major latex
                                                                                                                                               Monash University           response to HEV
                                                                 Medical Postgraduate Research Scholarshipthe human cellular and humoral response to thehumoralVIC allergen, the m
997607   Dr Fan Li                                               Dora                     Hepatitis E               Hepatitis E virus capsid protein processing and the VIC Medical Res
                                                                                                                                               Macfarlane Burnet Institute for
                                  NHMRC Postgraduate Scholarships Lush Biomedical Scholarship virus capsid protein processing and the immune responses induced by DNA immuimmune response
   459   Prof Sandra Gifford      NHMRC Project Grants                                                              A Ethnographic Study the HelathUniversity NeedsVIC
                                                                                                                                                South- and social           Living positive S
                                                                 Standard Project Grant Bad Blood, Bad Livers: An Qualatative Study of of Deakin East Asian Womenof HCVwith hepa
  7087   A/Pr Margaret Hellard                                   Australian Clinical Research ECF
                                  Early Career Fellowships (Australia)                                              INVESTIGATION OF THE NATURAL HISTORY OF COMMUNITY AC
                                                                                                                                               Monash University
                                                                                          INVESTIGATION OF THE NATURAL HISTORY OF COMMUNITY ACQUIHEP C IN A COHO          VIC
  7443   Dr Charles Harvey                                       Dora                     Correlation               Correlation outcomes responses toof New South chronic hepatitis C
                                                                                                                                               University outcomes following
                                  NHMRC Postgraduate Scholarships Lush Biomedical Scholarship of immune responses to of immune following immunotherapy inWalesimmunothera NSW
  8130   Dr Anouk Dev             NHMRC Postgraduate Scholarships                         Factors affecting the     Factors affecting in course of hepatitis C in South-East Asian wome
                                                                                                                                               Monash University
                                                                 Medical Postgraduate Research Scholarship course of hepatitis CtheSouth-East Asian women                 VIC
  8154   Dr Marc Le Mire          NHMRC Postgraduate Scholarships                         Persistence of duck       Persistence DNA in transient & persistent infection SA& persistent inf
                                                                                                                                               University DNA in transient
                                                                 Medical Postgraduate Research Scholarship hepatitis B virus of duck hepatitis B virusof Adelaide
  8175   Dr Jeffrey Post          NHMRC Postgraduate Scholarships                         Natural Scholarship       Natural history of infectionhepatitis C virus South Wales
                                                                 Medical Postgraduate Research history of primary hepatitis C virus primary University of Newinfection NSW
102421   Prof Eric Gowans         NHMRC Project Grants                                                              A vaccine for hepatitis C Macfarlane Burnet Institute for Medical Res
                                                                 Standard Project Grant A virus-like particle vaccine for hepatitis C virus. virus.                       VIC
102481   Dr Jason Mackenzie       NHMRC Project Grants                                                              Where and how the viruses roles of Australian encephalitis and deng
                                                                                                                                               University induced membranes
                                                                 Standard Project Grant Flavivirus replication - biogenesis, ultrastructure and causingof Queensland QLD
104892   A/Pr Allison Jilbert     NHMRC Project Grants                                                              Structure of hepadnaviral University of Adelaide
                                                                 Standard Project Grant Structure of hepadnaviral pre-genomic RNA.              pre-genomic RNA.          SA
111701   Prof John Crofts         CARG                                                                              How do social networks of epidemiology of the hepatitis C virus Res
                                                                                                                                               Macfarlane Burnet Institute the spread
                                                                                                                                                                          VIC
                                                                 ANCARD Project Grant Injecting drug users: social networks and molecularinjecting drug users affect for Medical of he
111710   Dr Elizabeth Grgacic     NHMRC Project Grants                                                               the ins and outs of hepatitis B virus Burnet hepatitis B Medical
                                                                                                                                               Macfarlane                 VIC
                                                                 Standard Project Grant Protein topogenesis andThe assembly/disassembly of the envelopedInstitute for virus. Res
115030   Dr Patrick Bertolino   NHMRC Project Grants                                                               Role of hepatocytes in tolerance
                                                                                                                                               University of and tolerance
                                                              New Investigator Grant Role of hepatocytes in inducing primary CD8+ T cell activation Sydney                NSW
136917   Prof Sandra Gifford    NHMRC Project Grants                                                               Investigating the needs of well being of men livingC.
                                                                                                                                               Deakin University            with
                                                              Standard Project Grant Identifying the social, personal and healthhealth andmen living with hepatitis VIC hepatitis C.
137841   Dr Patrick Bertolino   NHMRC Project Grants                                                               T cell suppression in transgenic cellof Sydney
                                                                                                                                               University
                                                              Standard Project Grant Transgenic mice : a unique model to reassess specific T micesuppression NSW
142606   Prof Geoffrey McCaughanNHMRC Project Grants                                                               Fibroblast Activation Protein and Liver Alfred
                                                                                                                                               Royal Prince
                                                              Standard Project Grant The Role of Fibroblast Activation Protein in Chronic Liver InjuryInjury Hospital     NSW
142607   Prof Geoffrey McCaughanNHMRC Project Grants                                                                pathogenesis of chronic hepatitisinfection associated
                                                                                                                                                C virus C virus           NSW
                                                              Standard Project Grant Novel approaches to thePathogenesis of hepatitis Royal Prince Alfred Hospital liver disease
145884   Dr Anthony Freeman                                   Medical Postgraduate Research Scholarship hepatitis C exposed uninfected injecting of New South Wales
                                NHMRC Postgraduate Scholarships                          Cellular immunity in                                  University drug users and injecting drug use
                                                                                                                   Cellular immunity in hepatitis C exposed uninfectedNSW   transfused thalas
149501   A/Pr David Anderson NHMRC Project Grants                                        Polarized epithelia and the natural history of hepatitis the liver
                                                                                                                                               Macfarlane                 VIC
                                                              Standard Project Grant with Research FellowshipHow viruses get in and out of viruses Burnet Institute for Medical Res
149534   A/Pr David Anderson Established Career FellowshipsNHMRC Research Fellowship                                natural history of hepatitis viruses Burnet Institute for
                                                                                                                                               Macfarlane                 viruses
                                                                                         Polarized epithelia & thePolarized epithelia & the natural history of hepatitis VIC Medical Res
156714   Dr Pantelis PoumbouriosNHMRC Project Grants                                                               How does C Virus C Virus infect cells?                 VIC
                                                              Standard Project Grant Molecular Mechanisms of HepatitisHepatitisentry. St Vincent's Institute of Medical Research
157128   Prof Susan Kippax      NHMRC Project Grants                                                               Blood awareness in Hepatitis C prevention South Wales
                                                                                                                                               University of C preventionNSW
                                                              Standard Project Grant An analysis of "blood awareness" for the purposes of Hepatitis New education          education and he
158010   A/Pr Allison Jilbert   NHMRC Project Grants                                                               Mutant strains of hepatitis B virus that Adelaide
                                                              Standard Project Grant Virulence determinants in hepadnavirus infection University of cause disease         SA
158011   A/Pr Allison Jilbert   NHMRC Project Grants                                                               Treatments for hepatitis B virus B virus
                                                                                                                                               University of Adelaide
                                                              Standard Project Grant Combination antiviral and immune therapies for hepatitisinfectioninfection. SA
164815   Dr Kaye Stenvers       NHMRC Project Grants                                                               TGF-beta receptor type III liver growth: malignant liver
                                                                                                                                               Ludwig Institute for Cancer Research
                                                                                                                                                                           of TGF-beta
                                                              Standard Project Grant TGF-beta receptor type III in normal and malignant in normal andModulation VIC growth activ
165702   Dr Amany Zekry                                       Medical Postgraduate Research Scholarship and Differential Gene Expression of Hepatitis C VirusNSWof Hepatitis C
                                NHMRC Postgraduate Scholarships                                                                                University of Sydney        Post
                                                                                         Immunopathogenesis Immunopathogenesis and Differential Gene Expression Liver Transp
191805   Prof Eric Gowans       NHMRC Project Grants                                                               Hepatitis C culture and control
                                                                                                                                               Macfarlane control of replication
                                                                                                                                                                          VIC
                                                              Standard Project Grant The in vitro culture of hepatitis C virus and approaches to the Burnet Institute for Medical Res
191820   Prof John Crofts       Established Career FellowshipsNHMRC Research Fellowship                            Uncoupled
                                                                                         Uncoupled Research Fellowship Research Fellowship                                VIC
                                                                                                                                               Macfarlane Burnet Institute for Medical Res
201700   Dr Joseph Sasadeusz NHMRC Project Grants                                                                   co-infection.              Melbourne
                                                              Standard Project Grant Studies of HIV and HBV Studies of HIV and HBV co-infection.Health                    VIC
207817   Dr MICHAEL BEARD NHMRC Project Grants                                                                     Oxidative Stress Hepatitis C Virus and Disease
                                                                                                                                               University of its Role     SA
                                                              New Investigator Grant Induction of Reactive Oxygen Species by in HCV Related Liver Adelaide in Liver Pathogenesis
209196   Mr Theo Gouskos                                      Dora                       Restoration               Restoration of HBV development ofof Melbourne VIC
                                                                                                                                               University compensatory mutations in the v
                                NHMRC Postgraduate Scholarships Lush Biomedical Scholarship of HBV replication fitness by the replication fitness by the development of compen
210109   A/Pr Julie Jonsson     NHMRC Project Grants                                                               Investigation of the role of the Renin-Angiotensin System
                                                                                                                                               University of Queensland
                                                              Standard Project Grant Investigation of the role of the Renin-Angiotensin System in hepatic fibrosis.QLD in liver fibro
210232   A/Pr Hans Netter       NHMRC Project Grants                                                               Synthesis of virus-like particles carrying a variety ofVIC
                                                                                                                                               Monash immune response against quasisp
                                                              Standard Project Grant Development of a HBV-specific carrier matrix to induce an University                  foreign epitopes
210356   Dr Ingrid Hickman                                    Dora                       The role of               The role of obesity and nutrition in chronic hepatitis C and
                                                                                                                                               University of liver disease
                                NHMRC Postgraduate Scholarships Lush Biomedical Scholarship obesity and nutrition in chronic hepatitis C and fatty Queensland QLD fatty liver d
219282   Prof Geoffrey Farrell                                C                          Centre                    Centre for Clinical improve outcomes in to improveNSW
                                                                                                                                               University of Sydney        outcomes
                                Centres for Research Excellence entre of Clinical Excellence for Clinical Research Excellence to Research Excellence chronic liver disease in chro
222887   Prof Andrew Lloyd      NHMRC Project Grants                                     The HITS study:           of transmission, natural history and primary South Wales
                                                                                                                                               University of New hepatitis C in
                                                                                                                                                                           outcome from pr
                                                              Large Scale Clinical Trials Project Grant modes HITS: a prospective cohort study of determinants ofNSW prisoners
222922   Dr Loren Brener                                      Public                     Health care workers andHealth care positive clients: a study of New South Wales
                                NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                University health care experiences
                                                                                                                                                                          NSW
                                                                                                                    hepatitis C workers and hepatitis C positive clients: a study of health
229304   Prof Sandra Gifford    NHMRC Project Grants                                                               Discrimination, hepatitis C inTrobe University
                                                                                                                                               to health care settings. VIC
                                                              Standard Project Grant Discrimination or Discretion? Factors contributing La discrimination of people with hepatitis C
234428   Mr Paul Myers                                        Public                     A cross-national          A cross-national longitudinal study ofhealth outcomes in and health o
                                                                                                                                               University Melbourne VIC
                                NHMRC Postgraduate Scholarships Health Postgraduate Scholarship longitudinal study of HCV risk practices andofHCV risk practices homeless yo
237056                                                        Dora                       Development of recombinant hepatitis of virus particles as a platform for theVIC as a of hepati
         Miss Patricia Vietheer NHMRC Postgraduate Scholarships Lush Biomedical Scholarship                                                    Monash University
                                                                                                                   Development B recombinant hepatitis B virus particles   delivery platform
253766   Prof Jacob George      NHMRC Project Grants                                                               NASH pathogenesis in man    University of Sydney       NSW
                                                              Standard Project Grant Molecular and cellular pathogenesis of nonalcoholic steatohepatitis: Insights from human stud
254666   Prof George Yeoh       NHMRC Project Grants                                                               Factors family in liver progenitor celldevelopmentand differentiation
                                                                                                                                               University proliferation of liver
                                                                                                                                                                          WA
                                                              Standard Project Grant The role of TNF and its receptor which affect the growth and of Western Australia precursor c
262012   Dr David Bowen                                       CJ Martin (Biomedical) ECF
                                Early Career Fellowships (Overseas)                                                Hepatitis C virus in the chimpanzee Institute of chimpanzee
                                                                                                                                               Centenary                  NSW
                                                                                         Hepatitis C virus replication and immunityreplication and immunity in theCancer Medicine and
262068   Dr Hani Tawk                                         Primary Health Care Scholarship B:prevention ofHepatitis B:prevention offrom different ethnic communities
                                NHMRC Postgraduate Scholarships                          Hepatitis                                             University of in familys NSW
                                                                                                                    liver disease in familys liver disease Sydney from different ethnic
262077   Dr Jason Tye-Din                                     Medical Postgraduate Researchin coeliac disease cells in coeliac disease Walter and Eliza Hall Institute
                                NHMRC Postgraduate Scholarships                          T cells Scholarship       T                                                      VIC
265603   Dr Mark Berzsenyi                                    Medical Postgraduate Research Scholarship
                                NHMRC Postgraduate Scholarships                                                    & genomics of GB virus & Hepatitis of GB virus Human
                                                                                                                                               Alfred Hospital             Hepatitis C Virus
                                                                                         Associations, outcomes Associations, outcomes C,genomics C Virus and C, VIC Immunodefi
268011   Dr Catherine Banwell NHMRC Project Grants                                                                 Choice or chance: contraceptive by National University
                                                                                                                                               Australian by women HCV and their
                                                                                                                                                                          ACT
                                                              Standard Project Grant Choice or chance: the social context of contraceptive use usewomen withwith hepatitis C repro
284420   A/Pr Hans Netter       NHMRC Development Grants Development Grant                                         Multi-component like particles as University delivery platform
                                                                                                                                               for the delivery of        VIC
                                                                                         Development of chimeric hepatitis B virus vaccine Monash a vaccineHIV-1 antigens for mult
293803   A/Pr Mark Gorrell     NHMRC Project Grants                                                               dipeptidyl peptidase gene family in
                                                                                                                                             Royal Prince Alfred Hospital
                                                              ANCARD Project Grant Roles of enzymes of theEnzymes important in human liver human liver                   NSW
295611   Dr Alexander ThompsonNHMRC Postgraduate Scholarships                          Studies Scholarship       Studies on the natural history of e hepatitis B
                                                                                                                                             St Vincent's Health
                                                              Medical Postgraduate Research on the natural history of e antigen negative chronicantigen negative VIC     chronic hepatitis B
296200   Dr Heidi Drummer      NHMRC Project Grants                                                               Hepatitis C Virus glycoproteins
                                                                                                                                             Macfarlane Burnet           VIC
                                                              Standard Project Grant Structure and function ofStructure and function of HCV glycoproteins Institute for Medical Res
300081                                                        Public                   ECF                       Risk of therapeutic injection-realted of Melbournevirus transmission a
                                                                                                                                             University blood-borne VIC
         Dr Michelle Kermode Early Career Fellowships (Australia) Health (Australia) Risk of therapeutic injection-realted blood-borne virus transmission amongst IDU and non-IDU
300579   Prof Lisa Maher       Career Development Fellowships                                                    Prevention of Blood-borne Virus Transmission among Injecting Drug
                                                                                                                                             University of Drug Users NSW
                                                              Population Health CDF Prevention of Blood-borne Virus Transmission among InjectingNew South Wales          (IDUs)
307818   Ms Katerina Ajami                                    Dora                     Functions                 Functions of Dipeptidyl Peptidase (DP)9
                               NHMRC Postgraduate Scholarships Lush Biomedical Scholarship of Dipeptidyl Peptidase (DP)9                     University of Sydney        NSW
323212   A/Pr David Moore      NHMRC Project Grants                                                              Ethno-epidemiology of psychostimulant-related An integrated ethno-e
                                                                                                                                             Curtin University of Technology
                                                              Standard Project Grant Improving understanding of psychostimulant-related harms in Australia: harms        WA
331309   Prof Peter Gage       NHMRC Project Grants                                                              Hepatitis virus                                         VIC
                                                              Standard Project Grant Studies of hepacivirus morphogenesis. assembly. Macfarlane Burnet Institute for Medical Res
331312   A/Pr Margaret Hellard NHMRC Project Grants                                                              Factors influencing hepatitis C virus infection inC virus infection Res
                                                                                                                                             Macfarlane hepatitis injecting drug users
                                                                                                                                                                         VIC
                                                              Standard Project Grant Behavioural, virological and immunological factors influencingBurnet Institute for Medicalin inje
331324   Dr Peter Higgs                                       Public                   Ethic Vietnamese           injectors and BBV transmission
                                                                                                                                             Macfarlane Burnet Institute for
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship heroinEthic Vietnamese heroin injectors and BBV transmissionMedical Res   VIC
334269   Dr Christopher DesmondNHMRC Postgraduate Scholarships                         Immunopathogenesis Hep B virus infection              Monash University
                                                              Medical Postgraduate Research Scholarship of Immunopathogenesis of Hep B virus infection                   VIC
334275   Dr Nicholas Walsh                                    Public                   Determinants of           Determinants of recruitment, engagement and health care in Australi
                                                                                                                                             Monash University
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship recruitment, engagement and management of IDUs in management of IDUs      VIC
334603   Prof Simon Mallal     NHMRC Project Grants                                                              Adaptation of Hepatitis C MurdochResponses
                                                                                                                                             to Host University          WA
                                                              Standard Project Grant Adaptation of Hepatitis C to Host HLA-Restricted Immune HLA-Type in Australian Population
344806   Dr David Iser         NHMRC Postgraduate Scholarships                         Pathogensis and ntauralPathogensis and ntaural history of liver disease in the setting of HIV/H
                                                              Medical Postgraduate Research Scholarship                                       the setting Health         VIC
                                                                                                                  history of liver disease inSt Vincent'sof HIV/HBV coinfection
349353                                                        RD
         Dr MICHAEL BEARD Career Development Fellowships Wright (Biomedical) CDF                                 response to hepatocyte response in HCV infection:SA role in and vir
                                                                                                                                             University modulating        its
                                                                                       Defining the hepatocyte Defining the HCV infection: its role toof Adelaide liver diseasemodula
351008   A/Pr Carolyn Day                                     Public                   ECF                       Impact drug dependenceUniversity of Hep C
                                                                                                                                              treatment dependence treatment on Hep C
                                                                                                                                                                         NSW
                               Early Career Fellowships (Australia) Health (Australia) Impact of injecting patterns and of injecting patterns and drugonSydney treatment outcomes fo
351579   A/Pr Elizabeth Powell NHMRC Project Grants                                                              How fatty liver causes and fibrogenesis in human liver disease
                                                                                                                                             University of Queensland QLD
                                                              Standard Project Grant The role of steatosis in promoting cellular injuryfibrosis
351642   Miss Meagan Walsh                                    Dora                     Investigation             Investigation of the mechanisms by of to hepatic fibrogenesis to he
                                                                                                                                             University which steatosis contributes
                               NHMRC Postgraduate Scholarships Lush Biomedical Scholarship of the mechanisms by which steatosis contributesQueensland QLD
358398   Prof Geoffrey Farrell Programs                       Program Grant                                      PROCESSES THAT CAUSE HUMAN LIVERAND CIRRHOSIS OF T
                                                                                                                                             University INJURY
                                                                                       MOLECULAR AND CELLULAR PATHOGENESIS OFLIVERof Sydney DISEASE                      NSW
358772   Dr Mark Douglas                                      CJ Martin (Biomedical) ECF influence of Hepatitis C Virus Genotype on Hepatic Lipid Metabolism. NSWLipid Metabo
                               Early Career Fellowships (Overseas)                     The                                                    C Virus Genotype on
                                                                                                                 The influence of HepatitisUniversity of Sydney Hepatic
376043   Dr Kerry-Lee Milner   NHMRC Postgraduate Scholarships                         Physiological basis       Physiological basis of insulin resistance in chronic hepatitis C virus in
                                                                                                                                              hepatitis C virus infectionNSW
                                                              Medical Postgraduate Research Scholarshipof insulin resistance in chronicGarvan Institute of Medical Research
381713   Dr Heidi Drummer      NHMRC Project Grants                                                              Neutralizing antibody responses in infected individuals. Medical Res
                                                                                                                                             Macfarlane Burnet Institute for
                                                              Standard Project Grant Characterization of neutralizing antibody responses in HCV HCV infected individuals.VIC
381732   A/Pr Rosemary Ffrench Career Development Fellowships Industry CDF                                       Development and testing Macfarlane Burnet strategy for Medical Res
                                                                                       Development and immunogenicity testing of             of a novel vaccine InstituteVIC
382911   Dr Benjamin Cowie                                    Public                   The seroprevalence, molecular characterisation &Melbourne Health
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                mathematical modelling of hepatitis B mod
                                                                                                                                                                         VIC
                                                                                                                 The seroprevalence, molecular characterisation & mathematical virus
384702   Prof Simon Mallal     Programs                       Program Grant                                      Interactions between adaptable pathogens, drugs and the human hos
                                                                                                                                              and the University
                                                                                       Interactions between adaptable pathogens, drugs Murdochhuman host                 WA
390708   Dr Karla Helbig                                      Peter                    Host Factors ModulatingHostSeverity of Hepatitis the Severity of Hepatitis Veterinary Science
                               Early Career Fellowships (Australia) Doherty (Biomedical) ECF                                                 Institute of Medical
                                                                                                                  the Factors Modulating C Virus Infection and CSA        Virus Infection
396700   Dr Nicholas Wood      NHMRC Project Grants                                                              Hepatitis B immunity in risk" children who risk" children
                                                                                                                                             The Children's Hospital at hepatitis B vaccin
                                                              New Investigator Grant Hepatitis B virus immunity in Indigenous and "at Indigenous and "atreceived NSW      Westmead
399284   Dr MICHAEL BEARD NHMRC Project Grants                                                                   The role of alcohol, Cyp2e1 and hepatitis homeostasis cell replicati
                                                                                                                                             University of Adelaide       liver
                                                              Standard Project Grant The role of Cyp2e1, alcohol and HCV in modulation of hepatocyte C virus inSA HCV biology
399285   Dr MICHAEL BEARD NHMRC Project Grants                                                                   Hepatitis C virus, chemokines and their viral viral SA
                                                                                                                                              other forms Adelaide
                                                              Standard Project Grant The role of CXCR3 chemokines in hepatitis C andUniversity of ofrole inhepatitis     hepatitis
400920   Prof Andrew Lloyd     NHMRC Project Grants                                                              Position and of T cells recruited to of HCV infected liver
                                                                                                                                              cells in HCV infected liver
                                                              Standard Project Grant Fine positioning and effector function function of TUniversitythe New South Wales   NSW
401146   Ms Heidi Coupland                                    Public                   Prevention and            Prevention and managemnet Indo-Chinese injecting drug users
                                                                                                                                             University of New South Wales
                                                                                                                                                                         NSW
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship managemnet of hepatitis C infection inof hepatitis C infection in Indo-Chinese
401522   Prof Elizabeth Powell Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of Queensland QLD
401526   Prof ROBERT TINDLE NHMRC Project Grants                                                                 HBsAg as a generic vaccine vector of Queensland QLD
                                                                                                                                             University
                                                              Standard Project Grant Development of Hepatitis B surface antigen as a generic vector for the delivery of foreign CTL
402577   Prof Jacob George     NHMRC Project Grants                                                              Host factors affecting hepatatis C of Sydney
                                                                                                                                             University
                                                              Standard Project Grant Host determinants of Hepatitis C-associated liver disease disease                   NSW
433900   A/Pr David Anderson Established Career FellowshipsNHMRC Research Fellowship                             Uncoupled
                                                                                       Uncoupled Research Fellowship Research Fellowship                                 VIC
                                                                                                                                             Macfarlane Burnet Institute for Medical Res
433908   Prof Eric Gowans      NHMRC Project Grants                                                              Supressor T cells in hepatitis C virus Burnet Institute for Medical Res
                                                                                                                                             Macfarlane TOLERANCEVIC
                                                              Standard Project Grant UNDERSTANDING HEPATITIS C VIRUS-SPECIFIC T CELL infection
433913   Dr Heidi Drummer      NHMRC Project Grants                                                               the Hepatitis function of the Hepatitis and E2.
                                                                                                                                            Macfarlane Burnet Institute for Medical Res
                                                                                                                                                                       VIC
                                                              Standard Project Grant Structure and function ofStructure and C Virus glycoproteins E1C Virus glycoproteins E1 and E
433914   Dr Elizabeth Grgacic  NHMRC Project Grants                                                             Identification of HBV fusionMacfarlane                 VIC
                                                              Standard Project Grant A new insight into hepatitis B infection:the HBV fusion peptideBurnet Institute for Medical Res
433929   A/Pr Heidi Drummer                                   RD
                               Career Development Fellowships Wright (Biomedical) CDF                             the Hepatitis function of the Hepatitis C Virus and Human Immunode
                                                                                                                                            Macfarlane Burnet Institute Virus glycoprote
                                                                                                                                                                       VIC
                                                                                       Structure and function ofStructure and C Virus and Human Immunodeficiency for Medical Res
433931   Dr Diah Elhassen                                     Peter                    Structual                Structual analysis of interactions between HCVof Medical Research t
                                                                                                                                            Queensland Institute E2 QLDreceptor class B
                               Early Career Fellowships (Australia) Doherty (Biomedical) ECF analysis of interactions between HCV E2 glycoprotein, scavenger glycoprotein, scav
433935   Dr Jacqueline Flynn                                  Public                   Stimulation and          Stimulation and maintenance of T cell infection
                                                                                                                                            Macfarlane Burnet Institute for HCV infect
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship maintenance of T cell responses in acute HCVresponses inVIC Medical Res  acute
433941                                                        Dora                     Role of the              Role of the variable regions of Hepatitis C Virus envelope glycoprotei
                                                                                                                                            Macfarlane Burnet Institute for Medical stru
                                                                                                                                                                       VIC
         Ms Kathleen McCaffrey NHMRC Postgraduate Scholarships Lush Biomedical Scholarship variable regions of Hepatitis C Virus envelope glycoprotein E2 in glycoprotein Res
436729   A/Pr Hans Netter      NHMRC Project Grants                                                             Design of applied for theMonash University
                                                                                                                                             prevention of hepatitis C and influenza of m
                                                                                                                                                                       VIC
                                                              Standard Project Grant Novel generic vaccine approachesvaccination tools directed against infectious pathogens viru
448325   Dr Kim Wilson         NHMRC Project Grants                                                              the Humoral Immune Response to HCV to identify VIC Research
                                                                                                                                            St Vincent's Institute of Medical
                                                                                                                                                                       Diagnostic
                                                              Standard Project Grant Detailed Investigation of Characterisation of the Immune Response to Hepatitis C Virusand Pr
453505   A/Pr Allison Jilbert  NHMRC Project Grants                                                             Resolution infections       University infections
                                                              Standard Project Grant Resolution of acute hepatitis B virusof acute hepatitis B virusof Adelaide        SA
453506   A/Pr Allison Jilbert  NHMRC Project Grants                                                             Immune therapies for infection
                                                                                                                                            University of B virus infection
                                                              Standard Project Grant Immune therapies for chronic hepatitis B virus chronic hepatitisAdelaide          SA
453507   A/Pr Allison Jilbert  NHMRC Project Grants                                                             Clonal proliferation of hepatocytes in chronic chronic B virus B virus
                                                                                                                                            University of Adelaide     SA
                                                              Standard Project Grant Clonal proliferation of hepatocytes and progression of liver disease in hepatitishepatitisinfectio
454640   A/Pr David Jackson    NHMRC Project Grants                                                             A New Method for Vaccine Design of Melbourne
                                                                                                                                            University
                                                              Standard Project Grant Using the Information inherent in Immune Responses to Design Vaccines VIC
455355   Prof Gregory Dore     Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of New South Wales     NSW
455985   A/Pr Julie Jonsson    NHMRC Project Grants                                                             A new model for fibrosis in chronic liver disease
                                                                                                                                            University of Queensland QLD
                                                              Standard Project Grant Hepatocyte replicative arrest, hepatic progenitor cells and the ductular reaction in hepatic fibro
457043   Dr Patrick Bertolino  NHMRC Project Grants                                                             Rapid T cell by the liver: a critical step towards
                                                                                                                                             the liver                 NSW
                                                              Standard Project Grant Understanding rapid T-cell clearanceclearance byUniversity of Sydney improved liver transp
468100   Prof Sharon Lewin     Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship Monash University                 VIC
491017   Dr Ashley Mansell     NHMRC Project Grants                                                             Toll-like receptor (TLR) signaling by Hepatitis Pathways
                                                                                                                                            Monash University          VIC
                                                              Standard Project Grant Suppression of Immune Immunomodulation of Inflammatory Signaling B e Antigen (HBeAg)
496602   Prof Grant Ramm       NHMRC Project Grants                                                             Understanding Liver Scarring in Children with Liver QLD Paediatric
                                                                                                                                            Queensland Institute of Medical due to
                                                                                                                                                                        Disease
                                                              Standard Project Grant Role of Chemoattractants in Hepatic Stellate Cell Recruitment and Fibrogenesis inResearchO
502028   Dr Catherine Croagh   NHMRC Postgraduate Scholarships                         The role of Hepatitis      Antigen status in the natural history and therapeutic outcomes of chr
                                                                                                                                            University Antigen in determining outcome
                                                              Medical Postgraduate Research Scholarship B EThe significance of the Hepatitis B Eof Melbourne VIC
508088   A/Pr Michael Beard    NHMRC Project Grants                                                             Host genes genes that HCV replication and and predict
                                                                                                                                            University of Adelaide      treatment respon
                                                              Standard Project Grant Identification of interferon stimulatedthat control limit HCV replication predictSA therapeutic o
508950   Prof David Jackson    Established Career FellowshipsNHMRC Research Fellowship                          Uncoupled
                                                                                       Uncoupled Research Fellowship Research Fellowship    University of Melbourne VIC
510104   Prof Lisa Maher       NHMRC Project Grants                                                             Trial of Hepatitis B Vaccine Completion in Injecting NSW Users
                                                                                                                                            University of New South Wales
                                                                                                                                                                       Drug
                                                              Standard Project Grant Randomised Controlled Hepatitis B Acceptability and Vaccine Incentive Trial (HAVIT)
510246   Prof Andrew Lloyd     Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of New South Wales     NSW
510424   Dr Peter Higgs                                       Public                   ECF                      How do long term injecting avoid hepatitis South Wales
                                                                                                                                            University of avoid infection?
                                                                                                                                                                       NSW
                               Early Career Fellowships (Australia) Health (Australia) Staying safe: How do long term injecting drug usersdrug users NewChepatitis C infection?
510428   Dr Fabio Luciani                                     Peter                    Modelling                Improving C design integrating forof sequence- Wales
                                                                                                                                            University Hepatitis C virus immunological
                                                                                                                                                                       NSW
                               Early Career Fellowships (Australia) Doherty (Biomedical) ECF the evolution of Hepatitisthevirus by of vaccines large New South and by predicting it
510448   Prof David Cooper     Programs                       Program Grant                                     Vaccines for AIDS and Hepatitis C. of New South Wales
                                                                                       HIV and HCV Vaccines and Immunopathogenesis.         University                 NSW
511201   Prof Elizabeth Powell NHMRC Project Grants                                                             Role of obesity in impaired treatment Queensland QLD and therap
                                                                                                                                            chronic hepatitis C: mechanisms
                                                              Standard Project Grant Role of obesity in impaired treatment response in University ofresponse in chronic hepatitis C:
511219   Dr Ingrid Hickman     NHMRC Project Grants                                                             Obesity and liver disease: in chronic liverliver injuryExercise and diet
                                                                                                                                            University of to disease: and
                                                              New Investigator Grant Obesity-related inflammation and insulin resistanceContributorsQueensland QLD the role or e
511902   Prof Paul Haber       Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of Sydney              NSW
512031   Dr Venessa Pattullo   NHMRC Postgraduate Scholarships                         The effect of exercise Lifestyle intervention in patients withofprofile hepatitis C.
                                                                                                                                            University Sydney          NSW
                                                              Medical Postgraduate Research Scholarship on insulin resistance and the adipokinechronic in obese versus non obe
512284   Dr David Bowen        NHMRC Project Grants                                                             Immune immune responses post-liver Sydney
                                                                                                                                             hepatitis of transplantation
                                                                                                                                                                       NSW
                                                              New Investigator Grant Hepatitis C virus-specific cellular responses to theUniversityC virus following liver transplantat
513896   Prof George Yeoh      NHMRC Project Grants                                                             growth, liver stem cells grow and develop into functional liver cells?
                                                                                                                                            University of Western Australia
                                                                                                                                                                       WA
                                                              Standard Project Grant Mechanisms underlying How do lineage commitment and differentiation of liver progenitor cel
513961   Dr Aibin Zhang                                       Australia - China Exchange Fellowship in growth,TNF-á and liver progenitordifferentiation of liver Australia cells
                               International (Exchange) Early Career Fellowships       Role of TNF-á                                           cells                   WA
                                                                                                                  lineage commitment andUniversity of Western progenitor
520312                         NHMRC Postgraduate Scholarships
         Dr Douglas - INACTIVATED Johnson                                              Humoral and neutralising antibody responses to self-adjuvanting recombinant HCV virus like
                                                              Medical Postgraduate Research Scholarship                                     University of Melbourne Hepatitis C virus
                                                                                                                Vaccine development and antibody response usingVIC
520671   Dr Scott Patterson    NHMRC Postgraduate Scholarships                         Clinical Scholarship     New therapies for advanced hepatitis B.
                                                                                                                                            University of hepatitis B VIC
                                                              Medical Postgraduate Research studies of novel antiviral therapies in advanced chronicMelbourne virus infection.
521807   Dr Michelle Giles                                    Peter                    Immunological changes Hepatitis B infection and pregnancy viral hepatitis infection
                               Early Career Fellowships (Australia) Doherty (Biomedical) ECF                                                  impact on
                                                                                                                during pregnancy and theAlfred Hospital                VIC
 543113   A/Pr Heidi Drummer     NHMRC Project Grants                                                               How variable regions in HCV E2 modulate entry andfor Medical
                                                                                                                                               Macfarlane Burnet Institute antibody media
                                                                                                                                                                            VIC
                                                                Standard Project Grant Role of the hepatitis C virus glycoprotein E2 variable regions in viralglycoprotein function. Res
 543137   A/Pr Anthony JaworowskiNHMRC Project Grants                                                                in chronic viral disease                               VIC
                                                                Standard Project Grant ITAM signalling proteins How HIV causes disease Macfarlane Burnet Institute for Medical Res
 543143   Prof Eric Gowans       NHMRC Project Grants                                                               A hepatitis C virus.
                                                                Standard Project Grant Multiple vector vaccine for novel HCV vaccine           University of Adelaide       SA
 543144   Prof Eric Gowans       NHMRC Project Grants                                                               to treat HCV infection.
                                                                Standard Project Grant A novel immunotherapy A new HCV cell therapy. University of Adelaide                 SA
 546249   Dr Jennifer Audsley                                   Australian Clinical Research ECF implications and outcomes of anti hepatitis B virus (HBV) treatment B virus (HBV) t
                                 Early Career Fellowships (Australia)                    Long-term                                             Monash University            VIC
                                                                                                                    Long-term implications and outcomes of anti hepatitis in HIV-HBV co
 567057                                                         CJ Martin (Biomedical) ECF
          Dr Alexander ThompsonEarly Career Fellowships (Overseas)                                                  Genetic determinants of clinical outcome and treatment
                                                                                                                                               University of Melbourne treatment respon
                                                                                         A whole genome association study for determinants of clinical outcome andVIC response in c
 567174   Miss Sarah Moneer                                     Dora                     Immune correlates of protection against HCV - a potential role for NK cells and NKR expressi
                                 NHMRC Postgraduate Scholarships Lush Biomedical Scholarship                                                   University infection
                                                                                                                    Innate immunity in Hepatitis C virus of Melbourne VIC
 568859   Dr Mark Danta          NHMRC Project Grants                                                               Defining permucosal transmission for acuteSouth infection
                                                                                                                                               University of New HCV gay menNSW
                                                                Standard Project Grant Defining risk and mechanisms of sexual transmisison of hepatitis C amongWales within high
 568885   Prof John Kaldor                                      C                        Centre for Clinical Research Excellence in Aboriginal Excellence in Aboriginal Health: Sexuall
                                 Centres for Research Excellence entre of Clinical Research Excellence                                         University of New South WalesNSW
                                                                                                                    Centre for Clinical Research Health: Sexually transmitted and bloodb
 568985   Prof Gregory Dore      NHMRC Partnerships                                      Evaluation of              Assessment and treatment of hepatitis C virus among injecting drug u
                                                                                                                                               University among injecting drug
                                                                                                                                                                            NSW
                                                                Partnership Projects for Better Health a model for assessment and treatment of HCVof New South Wales users in op
 594444   Prof Tony Butler       NHMRC Project Grants                                                                Treatment Prisons and University of New South Wales
                                                                                                                                                (HePATO)
                                                                Standard Project Grant Hepatitis C, Prisons andHepatitis C,OpportunitiesTreatment Opportunities (HePATO)    NSW
 603735   A/Pr Heidi Drummer     NHMRC Project Grants                                                               Structure glycoproteins the HCV glycoproteins VIC
                                                                Standard Project Grant Structure and Function of the HCVand Function ofMacfarlane Burnet Institute for Medical Res
 603755   Rachel Sacks-Davis                                    Public                   Relationships between phylogeny dont lie: predicting sources of HCV Institute forfrom in a coho
                                 NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                               Macfarlane Burnet infections Medical Res
                                                                                                                                                                            VIC
                                                                                                                    Genetics of hepatitis C viruses and social network structure social co
 603756   Ms Rebecca Winter                                     Public                   Examining drug-related morbidity and mortality and seviceandBurnet amongVIC Medical Res
                                 NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                               Macfarlane mortality and sevice utilisation
                                                                                                                                                                              for
                                                                                                                    Examining drug-related morbidity utilisation Instituteex-prisoners
 626906   A/Pr Michael Beard     Established Career FellowshipsNHMRC Research Fellowship                            Uncoupled
                                                                                         Uncoupled Research Fellowship Research Fellowship     University of Adelaide       SA
 628953   Dr Eu Jin Lim          NHMRC Postgraduate Scholarships                         The Effects of Hepatitis C Viral Proteins On Liver Fibrosis In of Melbourne Immunosuppressa
                                                                Medical Postgraduate Research Scholarship                                        and Transplant Medications
                                                                                                                    The Effects of Hepatitis CUniversity The Setting of VICon The Liver
 630463   A/Pr David Wilson      NHMRC Project Grants                                                                 evaluation of cost-effectiveness of of New South Wales interventio
                                                                                                                                                epidemic hepatitis strategies in
                                                                                                                                                                            NSW
                                                                Standard Project Grant Modelling and economicModelling and hepatitis C Universitymitigation C biomedical Australia
 630483   Prof Lisa Maher        NHMRC Project Grants                                                               Hepatitis C Vaccine Preparedness Study South Wales
                                                                                                                                               University of New
                                                                Standard Project Grant Hepatitis C Vaccine Preparedness Study: Investing in Infectious Disease Prevention   NSW
 630732   Dr Anna Olsen                                         Australian Training ECF for Aboriginal and Torres Strait Islander Healthtreatment andof New care health care among A
                                 Early Career Fellowships (Australia)                                               A study of hepatitis B Research
                                                                                                                                               University health and among  NSW
                                                                                         Liver spots: A study of Hepatitis B knowledge, knowledge, treatment South WalesIndigenous In
 630733   Dr Rowena Bull                                        Peter                    Virus-host                 Understanding hepatitis virus chronicity
                                                                                                                                               University of New
                                 Early Career Fellowships (Australia) Doherty (Biomedical) ECF interactions contributing to hepatitis C C virus infection South Wales       NSW
 630754   Bethany White                                         Public                   Hepatitis C vaccine preparedness: feasibility preparedness vaccine trials Wales
                                 NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                               University
                                                                                                                    Hepatitis C Vaccine of field-based of New South NSW
 637350   Dr Marc Pellegrini     Career Development Fellowships Clinical CDF                                        Indentifying and signalling for chronic viral diseases
                                                                                                                                               Walter and to promote immune VIC
                                                                                         Trageted manipulation of host genesnew treatmentspathwaysEliza Hall Institute clearance o
1001144                                                         C                        Reducing Population Health Researchhealth, social and economic use in Australia
                                                                                                                    Reducing the                of injecting drug burden of for Medical Res
                                                                                                                                                                            VIC
          Prof Margaret Hellard Centres for Research Excellence entre for Research Excellence in the health, social and economic burden Macfarlane Burnet Institute injecting drug us
1003741                                                         RD
          Dr Meredith O'Keeffe Career Development Fellowships Wright (Biomedical) CDF                               The involvement of dendritic cells in the first Institute for
                                                                                                                                               Macfarlane Burnet line defense against p
                                                                                         Dendritic cells in innate immunity and their potential clinical manipulation of VIC Medical Res
1003767   Prof Jacob George      NHMRC Project Grants                                                               Endocannabinoids in chronic hepatitis C
                                                                                                                                                C
                                                                Standard Project Grant The role of endocannabinoids in chronic hepatitis University of Sydney               NSW
1004242                                                                                                             The role of obesity, insulin (steatosis) Queensland (steatosis) in hum
                                                                                                                                               University of in human disease
          Prof Elizabeth Powell Established Career FellowshipsPractitioner Fellowship The role of obesity, insulin resistance and fatty liverresistance and fatty liverQLD and strategi
1004847   A/Pr Allison Jilbert   NHMRC Project Grants                                                               Hepatitis B Circular DNA University Circular DNA SA
                                                                Standard Project Grant Hepatitis B Virus Covalently Closed Virus Covalently Closed of Adelaide
1006331   Dr Gail Matthews       NHMRC Project Grants                                                               Evidence for naturally occurring resistance South Wales drugs in
                                                                                                                                               University of New Drugs (DAAs)
                                                                                                                                                                            NSW
                                                                Standard Project Grant Evaluation of naturally occurring resistance to Direct Acting Antiviralto antiviral HCVin individup
1006592   Dr Marc Pellegrini     NHMRC Project Grants                                                               Understanding the immune mediated pathology: of chronic and ma
                                                                                                                                               Walter and Eliza Hall Institute
                                                                                                                                                                            VIC
                                                                New Investigator Grant Chronic active viral persistence versus hosthost factors that limit clearancean analysisviruses
1006759   A/Pr David Booth       NHMRC Project Grants                                                               IL28B and hepatitis virus University of Sydney response
                                                                Standard Project Grant The effect of IL28B haplotype on hepatitis C C           infection and treatment NSW
1011024   Prof Stephen Locarnini NHMRC Project Grants                                                               Can Hepatitis PATHOGENIC AND ONCOGENIC SIGNIFICANCE OF
                                                                                                                                               Melbourne progression to Liver Cancer?
                                                                Standard Project Grant ANTIVIRAL DRUG RESISTANT HBV: B therapy enhance theHealth                            VIC
1011319   Prof Ian James         NHMRC Project Grants                                                               Statistical host-viral genetic associations
                                                                                                                                               Murdoch University
                                                                Standard Project Grant Statistical issues in the analysis of issues in host-viral association studies WA
1016351   Prof Andrew Lloyd      NHMRC Partnerships                                      Prevention and             Prevention and treatmentUniversity of
                                                                                                                                                 of viral hepatitis amongstNSW
                                                                Partnership Projects for Better Health treatment of viral hepatitis amongst prisoners New South Wales       prisoners
1017139   Dr Paul Clark          NHMRC Postgraduate Scholarships                         Individualising care       Individualising care hepatitis C: predicting side effects
                                                                                                                                               University of New South WalesNSW
                                                                Medical Postgraduate Research Scholarshipfor patients with chronic of patients with chronic hepatitis C and treatment
1017465   Mr Jesse Toe                                          Dora                                                                            host immune effector function
                                                                                                                    Clearing chronic infectious diseases Eliza Hall Institute
                                                                                         Clearing chronic infectious diseases – enhancing Walter and – enhancing host immune effect
                                 NHMRC Postgraduate Scholarships Lush Biomedical Scholarship                                                                                VIC
1017784   Dr Uma Devi                                           Public                   Hepatitis B Virus          HBV drug Impact on the University of Program
                                                                                                                                                vaccine escape
                                 NHMRC Postgraduate Scholarships Health Postgraduate Scholarship Drug Resistance:resistance and ImmunisationMelbourne VIC
1018023   Dr Joseph Doyle                                      Medical Postgraduate Research Scholarship
                                 NHMRC Postgraduate Scholarships                                                  Early Virus in Australia Macfarlane Burnet Institute for
                                                                                       Early Treatment of Hepatitis CTreatment of Hepatitis C Virus in Australia VIC Medical Res
1018079   Dr Kate O'Connor                                     Medical Postgraduate Research Scholarship
                                 NHMRC Postgraduate Scholarships                                                  Analysis of the of the functional of the of the IL28B genotype on hepa
                                                                                                                                             effect effect Sydney        NSW
                                                                                       Functional pharmacogenetics: Analysis functional University of IL28B genotype on response to
1020175   A/Pr Heidi Drummer     NHMRC Project Grants                                                             Variable regions E2 variable regions E2virus entry,VIC
                                                                                                                                            Macfarlane in                 immunogenicity
                                                               Standard Project Grant Roles of the hepatitis C virus glycoproteinof HCV glycoprotein Burnet Institute for Medical Resa
1022144   Dr Michael Gantier     NHMRC Project Grants                                                             microRNA regulation       Monash University
                                                               New Investigator Grant microRNA regulation of antiviral responses of antiviral responses                  VIC
1023437   Prof Carla Treloar     NHMRC Project Grants                                                             Hepatitis C transmission and intimate injectors
                                                                                                                                            University of New South Wales
                                                               Standard Project Grant Understanding and preventing hepatitis C transmission within sexual partnerships   NSW
1024406   Prof Sharon Lewin      NHMRC Project Grants                                                             HIV-HBV co-infection
                                                               Standard Project Grant Liver disease in HIV-HBV co-infection                 Monash University            VIC
1027641   A/Pr Michael Beard     NHMRC Project Grants                                                             Imaging the hepatitis C virus life cycle Adelaide
                                                               Standard Project Grant Imaging the hepatitis C virus life cycle in real-time University of in living cellsSA
1028432   Prof Gregory Dore      Established Career FellowshipsPractitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of New South Wales     NSW
1032096   Dr Amany Zekry         NHMRC Project Grants                                                             Liver inflammation and hepatitis C of New
                                                                                                                                            University
                                                               New Investigator Grant Inflammatory mediators of liver injury in chronic chronic hepatitis C South Wales  NSW
1034029   A/Pr Michael Kotiw     NHMRC Project Grants                                                             Development of a of Hepatitis B virus like particles expressing
                                                                                                                                            University of Southern the dual prevention
                                                                                                                                                                         QLD
                                                               Standard Project Grant Construction and immunogenic evaluation novel recombinant vaccine forQueensland T and
1035383   Dr Jason Grebely       Career Development Fellowships                                                   Epidemiology, natural hepatitis C treatment of HCVNSW
                                                                                                                                            University of infection in injecting
                                                                                                                                                                          in injecting drug
                                                               Population Health CDF Epidemiology, natural history and treatment of history and virusNew South Wales drug user
1038356   Dr Jane Davies                                       Medical Postgraduate Research Scholarship End of Epidemiology Territory: epidemiology, of Health NTInfection in the
                                 NHMRC Postgraduate Scholarships                                                                            Menzies School burden ofB      disease
                                                                                       Hepatitis B in the Top The the Northern and Disease Burden of Hepatitis Researchand hea
1039019   Dr Roslyn Vongsuvanh                                 Medical Postgraduate Research on the pathogenesis and early diagnosis of hepatocellular carcinoma
                                 NHMRC Postgraduate Scholarships                       Studies Scholarship                                  University of diagnosis hepatocellular ca
                                                                                                                  Studies on the pathogenesis and earlySydney ofNSW
1039055   Dr Kasha Singh                                       Medical Postgraduate Research Scholarship
                                 NHMRC Postgraduate Scholarships                                                  in fibrosis mechanisms of progression in HIV-Hepatitis B co-infectio
                                                                                                                                            Monash University            VIC
                                                                                       The role of stellate cells Dissectingand liver diseaseliver disease progression in HIV-Hepatitis
1039597   Prof Paul Hertzog      NHMRC Development Grants Development Grant                                       Development of new antivirals. University
                                                                                       Development of new antivirals.                       Monash                       VIC
App     Start
                1995   1996     1997    1998      1999      2000      2001      2002   2003   2004   2005   2006   2007
Year    Year
 1994    1995 $38,283 $100,333 $90,668 $122,478   $34,282             $76,979
 1995    1996          $49,572 $38,649 $22,443    $43,633   $55,709
1995   1996   $16,864    $2,864    $14,273    $17,635     $8,884
1996   1997             $34,689    $66,833    $75,870    $65,759    $34,176
1997   1998                       $142,130   $162,752   $141,476
1997   1998                       $105,555   $117,876    $99,385
1997   1998                        $51,976    $59,237    $52,065
1997   1999                                   $15,461    $29,747    $29,792
1997   1999                                   $40,094    $29,906
1997   1999                                   $54,956    $40,044
1997   1999                                   $18,407    $41,593
1997   1999                                   $41,010    $18,990
1997   1999                                   $26,292    $29,744    $18,964
1997   1999                                   $41,333    $57,203    $36,464
1997   1999                                   $24,629    $20,371
1997   1999                                   $32,181    $66,352    $66,467
1997   1999                                   $25,765    $16,235
1997   1999                                   $30,179    $99,821
1997   2000                                              $37,500    $27,500
1997   1998                        $24,505    $75,480    $39,678    $58,319
1998   1999                                  $131,278   $113,348   $130,889     $3,280
1998   1999                                   $95,564    $83,716    $95,594
1998   1999                                  $155,313   $135,033   $152,562
1998   1999                                   $70,428    $62,365    $67,944     $2,991
1998   1999                                   $25,497    $26,889    $27,255    $13,782     $632
1998   1999                                   $25,497    $26,889    $27,255                $337
1998   1999                                   $17,635    $18,571    $18,842     $5,799    $5,015
1999   2000                                              $56,296    $29,613
1999   2000                                              $38,173    $79,157    $78,325   $63,500
1999   2000                                              $18,571    $18,842    $19,214    $9,749   $443
1999   2000                                              $26,889    $27,255    $27,793
1999   2000                                              $26,889    $27,255
1999   2000                                              $26,889    $27,255              $14,904
1999   2000                                              $65,418    $66,882    $66,713
1999   2001                                                        $199,522   $135,359
1999   2000                                              $51,278    $54,588
1999   2000                                             $172,182   $241,605   $130,081
1999   2000                                              $62,501    $65,854    $69,530
1999   2000   $49,416    $52,588    $57,658
2000   2001             $107,785   $108,121
2000   2001              $90,475    $91,035    $91,035
2000   2001              $65,285    $65,621    $65,621
2000   2001              $70,380    $70,828    $70,828
2000   2001              $27,255    $27,793    $28,432      $508
2000   2001              $70,285    $70,621    $70,621    $70,621    $76,621
2000   2001              $66,366    $95,000    $99,250   $116,250   $118,500   $120,500
2000   2001             $120,475   $121,035   $121,035
2000   2001              $95,285   $100,828
2000   2001             $125,380   $125,828   $125,828
2000   2001              $75,380    $75,828    $75,828
2000   2001             $120,285   $120,621   $120,621
2000   2001              $27,255    $27,793    $14,099
2001   2002                        $150,770   $150,770   $150,770
2001   2002                        $130,000   $135,000   $106,875
2001   2002                         $65,330    $70,440
2001   2002                        $125,440   $125,440   $125,440
2001   2002                         $19,214    $19,659    $16,050
2001   2002                         $82,330    $82,330    $82,330
2001   2002                        $135,550   $135,550   $135,550
2001   2002                         $24,328    $24,889    $10,612
2001   2003                                   $400,000   $400,000   $400,000   $400,000   $400,000
2002   2003                                   $187,000   $187,000   $187,000   $187,000   $200,250
2002   2003                                     $9,910    $20,484    $24,941    $14,675      $270
2002   2003                                   $126,000   $125,625   $130,625    $37,500
2002   2003                                    $14,704    $20,484    $20,837    $15,938
2002   2003                                    $19,659    $20,484    $20,837                 $627
2002   2003                                   $107,750   $107,750
2002   2003                                    $83,500    $83,500    $83,500
2002   2003                                    $77,040    $87,232    $21,427    $74,750    $38,000
2002   2003                                    $19,659    $20,484    $22,496     $2,171      $735
2002   2003                                    $28,432    $29,489    $30,014    $15,342
2003   2004                                               $29,489    $30,014    $30,600    $15,668
2003   2004                                              $144,525   $115,625
2003   2004                                               $34,875   $104,625
2003   2005               $79,750
2003   2004    $29,489    $30,014     $30,600      $15,754
2003   2004   $160,250   $160,250    $160,250
2003   2004    $64,750    $66,000     $67,250       $68,500
2003   2004    $85,250    $87,250     $89,000       $90,500
2003   2004    $20,484    $20,837     $21,231       $10,963
2004   2005              $215,810    $225,810     $170,810
2004   2005              $160,250    $160,250     $160,250
2004   2005              $323,375    $359,375     $280,688
2004   2005               $26,309     $26,817       $27,563
2004   2006                    $1     $30,600       $31,422
2004   2005               $55,326     $30,600       $15,754
2004   2005              $160,250    $160,250     $160,250
2004   2005               $30,014     $30,600       $31,422
2004   2005               $87,250     $89,000       $90,500
2004   2005               $66,000     $38,333       $68,500
2004   2005              $138,125    $138,125     $138,125
2004   2005               $20,838     $21,231       $10,963
2004   2005              $947,387    $965,387     $965,387
2004   2005               $46,114     $93,541       $45,473
2005   2006                           $16,300       $15,754
2005   2006                          $154,250     $157,628
2005   2006                                         $92,250
2005   2006                            $30,600      $31,422
2005   2006                         $1,173,888   $1,197,366
2005   2006                            $67,250      $68,500
2005   2006                          $164,100       $49,663
2005   2006                          $148,500     $151,878
2005   2006                          $149,250     $152,431
2005   2006                          $108,375     $100,463
2005   2006                            $21,231      $21,866
2005   2006                            $56,625      $55,500
2005   2006                          $143,500     $146,556
2005   2006                          $211,700     $216,560
2006   2007                                       $119,000
2006   2007                                       $140,225
2006   2007   $174,200
2006   2007    $94,100
2006   2008
2006   2007    $68,500
2006   2007    $21,866
2006   2007    $21,866
2006   2007   $128,075
2006   2007   $126,500
2006   2007   $122,325
2006   2007   $117,225
2006   2007   $136,625
2006   2007   $144,675
2006   2007
2006   2007   $172,250
2006   2007   $134,550
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2008   2009
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2007   2008
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2009
2008   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2009   2010
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012

              Expenditure $2,011,775 $2,821,309 $2,444,439 $2,795,067 $2,486,650 $4,108,655 $6,082,295 $7,218,193
              # of grants     37         40         33         36         29         36         42         54
                                                                        Broad Research    Field Of   Research
2008   2009   2010   2011   2012   2013   2014   2015   2016   Total
                                                                             Area        Research      KW 1
                                                               $463,022 Basic Science      Medical Virology
                                                                                           Epidemiology
                                                               $210,005 Clinical Medicine and Science HEPATITIS B
 $60,520   Basic Science                     HEPATITIS C
                              Medical Virology
$277,327                      Immunology HEPATITIS classif
           Clinical Medicine and Science not elsewhereC
$446,359   Basic Science                     HEPADNAVIRUSE
                              Medical Virology
$322,816   Basic Science                     HEPATITIS C VIRU
                              Medical Virology
$163,278   Basic Science                     HEPATITIS B VIRU
                              Medical Virology
 $75,000   Public Health      Health Information Systems (incl.
 $70,000   Public Health      Health Counselling
 $95,000   Basic Science      Medical Virology
 $60,000   Public Health      Medical Virology
 $60,000   Basic Science      Medical Virology
 $75,000   Public Health      Health Information Systems (incl.
$135,000   Public Health      Health Information Systems (incl.
 $45,000   Public Health      Health Information Systems (incl.
$165,000   Public Health      Health Information Systems (incl.
 $42,000   Public Health      Health Information Systems (incl.
$130,000   Public Health      Health Information Systems (incl.
 $65,000   Public Health      Health Promotion
$197,982   Basic Science                     RNA
                              Biomedical engineering and bioph
$378,794   Public Health      Medical Virology
$274,875   Basic Science                     HEPATITIS B VIRU
                              Medical Virology
$442,908   Public Health      Health Information Systems (incl.
$203,728   Basic Science                     HEPATITIS C VIRU
                              Medical Virology
 $94,055                      Medical Virology
           Clinical Medicine and Science HAPATITIS C
 $79,978                      Immunology ALLERGY
           Clinical Medicine and Science not elsewhere classif
 $65,862                      Medical Virology
           Clinical Medicine and Science HEPATITIS E VIRU
 $85,909   Public Health      Epidemiology HEPATITIS C
$259,155   Public Health                     HEPATITIS C
                              Public Health and Health Services
 $66,819   Basic Science                     CHRONIC HEPATI
                              Medical Virology
 $81,937   Public Health      Epidemiology HEPATITIS
 $54,144   Basic Science                     HEPADNAVIRIS
                              Medical Virology
 $69,048                      Infectious Diseases
           Clinical Medicine and Science HEPATITIS C VIRU
$199,014                      Medical Virology
           Clinical Medicine and Science cell-mediated immu
$334,881   Basic Science                     Assembly of flavivir
                              Medical Virology
$105,866   Basic Science                     Encapsidation
                              Medical Virology
$543,868   Public Health      Epidemiology ethnography
$197,885   Basic Science                     targets for antiviral
                              Medical Virology
        $159,663    Basic Science                     CD8 T lymphocytes
                                       Immunology not elsewhere classif
        $215,906    Public Health                     Access to Services
                                       Public Health and Healthhealth ca
        $272,546    Basic Science                     CD8 T lymphocytes
                                       Immunology not elsewhere classif
        $196,528    Basic Science      Hepatology Cell surface peptida
        $212,037                       Hepatology
                    Clinical Medicine and Science Pathogenesis of ch
          $83,988                      Medical and Cellular immunolog
                    Clinical Medicine and Science Health Sciences not
        $358,770    Basic Science                     Chronic viral infecti
                                       Medical Virology
        $615,866    Basic Science      Not Allocated N/A
        $362,546    Basic Science                     Hepatitis C virus
                                       Medical Virology
        $196,113    Public Health                     Blood
                                       Health Promotion awareness
        $377,037    Basic Science                     Ability of viral varian
                                       Medical Virology
        $227,037    Basic Science                     Prime-boost protoc
                                       Medical Virology
        $361,528    Basic Science                     Cre/lox Biology not
                                       Biochemistry and Cell transgenic m
          $69,147                      Transplantation Immunology
                    Clinical Medicine and Science Cholestatic hepatiti
        $452,310    Basic Science                     antiviral agents
                                       Medical Virology
        $371,875    Public Health      Epidemiology Blood-borne viruse
        $135,770                       Infectious Diseases
                    Clinical Medicine and Science Antiviral Resistance
        $376,320                       Hepatology
                    Clinical Medicine and Science Gene Array
          $54,923   Basic Science                     hepatitis
                                       Medical Virology
        $246,990                       Hepatology
                    Clinical Medicine and Science angiotensin
        $406,650    Basic Science                     Delivery of a variety
                                       Medical Virology
          $59,829   Public Health                     diet
                                       Nutrition and Dietetics
       $2,000,000                      Gastroenterology and Hepatology
                    Clinical Medicine and Science Cirrhosis
        $948,250                       Infectious Diseases
                    Clinical Medicine and Science Hepatitis C
          $70,281   Public Health                     Attitudes/Behavior
                                       Social and Community Psycholog
        $419,750    Public Health                     Barriers to Services
                                       Public Health and Health primary
$579      $72,541   Public Health      Not Allocated health outcomes ho
          $61,607   Basic Science                     Hepatitis B virus en
                                       Medical Virology
        $215,500                       Gastroenterology and Hepatology
                    Clinical Medicine and Science Gastroenterology
        $250,500    Basic Science                     hepatocarcinogene
                                       Cell Development (incl. Cell Divis
        $298,449    Basic Science      Hepatology acute infection
          $65,546   Public Health      Family Care Antenatal screening
        $103,277    Basic Science                     Autoimmunity
                                       Cellular Immunology
        $105,771                       Gastroenterology
                    Clinical Medicine and Science HCV
        $260,150    Public Health                     hepatitis C
                                       Public Health and Health Services
        $139,500                       Medical Virology
                    Clinical Medicine and Science HIV/AIDS
                                                                $79,750   Basic Science                     Pathogenesis
                                                                                             Gastroenterology and Hepatology
                                                              $105,857    Basic Science                     Drug
                                                                                             Medical Virology resistant muta
                                                              $480,750    Basic Science                     envelope glycoprote
                                                                                             Medical Virology
                                                              $266,500    Public Health                     Hepatitis C
                                                                                             Public Health and Health Services
  $92,500                                                     $444,500    Public Health                     BBV
                                                                                             Public Health and Health Services
    $442          $314                                          $74,271   Basic Science                     Hepatitis C
                                                                                             Gastroenterology
                                                              $612,430    Public Health                     epidemiology
                                                                                             Public Health and Health Services
                                                              $480,750    Basic Science                     antiviral agents
                                                                                             Medical Virology
                                                              $963,438    Public Health      Epidemiology genetic testing
                                                                $80,689   Public Health                     Vietnamese IDU
                                                                                             Public Health and Health Services
  $32,003      $16,359                                        $110,385                       Cellular Immunology
                                                                          Clinical Medicine and Science Hepatitis B
                                                              $101,680    Public Health                     Hepatitis C
                                                                                             Public Health and Health Services
                                                              $480,750                       Immunogenetics
                                                                          Clinical Medicine and Science MHC
  $16,042                                                     $108,078    Basic Science                     HAART
                                                                                             Medical Virology
  $92,500      $94,250                                        $453,500                       Medical Virology
                                                                          Clinical Medicine and Science Hepatitis C
  $69,750      $45,313      $51,375                           $339,271    Public Health      Epidemiology Hepatitis C virus
                                                              $414,375                       Gastroenterology and Hepatology
                                                                          Clinical Medicine and Science apoptosis
     $676                                                       $53,708                      Hepatology
                                                                          Clinical Medicine and Science apoptosis
$1,024,681   $1,025,481                                      $4,928,324                      Hepatology
                                                                          Clinical Medicine and Science Hepatic ischaemia
   $77,250      $78,750                                       $341,127    Basic Science                     Fatty
                                                                                             Medical Virology liver
   $30,881      $23,350                                         $86,285                      EndocrinologyChronic Hepatitis C
                                                                          Clinical Medicine and Science
 $166,198                                                     $478,077    Basic Science                     Evolution of viral se
                                                                                             Medical Virology
 $147,042      $96,250      $85,728                           $421,270                       Biotechnology not elsewhere clas
                                                                          Clinical Medicine and Science Cellular Immunity
   $16,042                                                      $78,064   Public Health      Epidemiology Biostatistics
$1,197,366   $1,120,613   $1,038,095                         $5,727,327                      Cellular Immunology
                                                                          Clinical Medicine and Science Complications of an
   $69,750      $71,250                                       $276,750    Basic Science                     anti-viral
                                                                                             Medical Virology
                                                              $213,763                       Infectious Diseases
                                                                          Clinical Medicine and Science Epidemiology
 $155,142                                                     $455,521                       Gastroenterology and
                                                                          Clinical Medicine and Science Cyp2e1 Hepatology
 $155,586                                                     $457,268                       Medical Virology
                                                                          Clinical Medicine and Science Hepatitis C virus
 $113,136                                                     $321,974                       Infectious Diseases
                                                                          Clinical Medicine and Science Chemokines
  $22,257                                                       $65,354   Public Health                     Hepatitis C
                                                                                             Public Health and Health Services
  $61,125      $61,250      $62,392                           $296,892                       Hepatology
                                                                          Clinical Medicine and Science Hepatitis C
 $149,586                                                     $439,643    Basic Science                     hepatitis
                                                                                             Cellular Immunology B
 $182,116                                                     $610,376                       Hepatology
                                                                          Clinical Medicine and Science Chronic liver diseas
 $121,500     $123,750     $126,101    $128,371   $130,553    $749,275                       Biotechnology not elsewhere clas
                                                                          Clinical Medicine and Science Antiviral, Viral Hepa
 $143,243     $146,242                                        $429,710    Basic Science                     hepatitis C virus
                                                                                             Medical Virology
$177,950    $181,679                                                      $533,828    Basic Science                     membrane fusion
                                                                                                         Medical Virology
 $95,993      $98,117                                                     $288,210    Basic Science                     viral
                                                                                                         Medical Virology entry mechanis
 $90,500      $90,500     $94,250     $97,769     $99,431                 $472,450    Basic Science                     Cellular receptors
                                                                                                         Medical Virology
 $87,188      $71,250     $72,508                                         $299,446                       Medical        E2
                                                                                      Health Services Research Virology glycoprotein
 $22,257      $22,677     $12,409                                           $79,209                      Cellular Immunology
                                                                                      Clinical Medicine and Science Acute Hepatitis C in
 $22,257      $22,677     $12,409                                           $79,209   Basic Science                     Hepatitus C Virus
                                                                                                         Medical Virology
$130,700    $133,554                                                      $392,328    Basic Science                     DNA
                                                                                                         Medical Virology vaccine
$129,036    $131,931                                                      $387,467    Basic Science                     Antibodies
                                                                                                         Medical Virology
$119,618    $122,242                                                      $364,185    Basic Science                     Covalently closed c
                                                                                                         Infectious Diseases
$119,618    $122,242                                                      $359,085                       Hepatology
                                                                                      Clinical Medicine and Science Antiviral
$140,446    $143,487                                                      $420,558                       Hepatology
                                                                                      Clinical Medicine and Science Hepatocyte prolifera
$188,907    $192,990                                                      $526,572                       Infectious Diseases
                                                                                      Clinical Medicine and Science dendritic cell targeti
$163,275      $84,175     $85,774     $87,318                             $420,542                       Infectious Diseases
                                                                                      Clinical Medicine and Science acute hepatitis, chro
$175,821    $179,612                                                      $527,683                       Hepatology
                                                                                      Clinical Medicine and Science ductular reaction
$137,282    $140,302                                                      $412,134    Basic Science                     CD8+
                                                                                                         Cellular Immunology T lymphocyte
 $70,625      $72,125      $73,495    $74,818     $76,090                 $367,153                       Infectious Diseases
                                                                                      Clinical Medicine and Science Anti-viral immunity
$176,985    $180,950     $184,386                                         $542,321    Basic Science                     Hepatitis B
                                                                                                         Infectious Diseases
$192,300    $196,571     $200,304                                         $589,175                       Hepatology
                                                                                      Clinical Medicine and Science Bile acids
 $32,003      $32,628      $23,712                                          $88,343                      Gastroenterology and Hepatology
                                                                                      Clinical Medicine and Science hepatic fibrosis
$127,110    $129,825     $132,290                                         $389,225                       Medical Virology
                                                                                      Clinical Medicine and Science Antiviral
$150,250    $153,250     $156,161   $158,972     $142,949                 $761,582                       Immunology Vaccine developme
                                                                                      Clinical Medicine and Science not elsewhere classif
$194,860    $183,453       $85,042                                        $463,355    Public Health                     acceptability
                                                                                                         Public Health and Health Services
 $98,875    $100,975     $102,893   $104,745     $106,526                 $514,014                       Infectious Diseases
                                                                                      Clinical Medicine and Science Cellular immunolog
 $17,438      $71,250      $72,508    $73,813      $56,301                $291,310    Public Health                     Public health
                                                                                                         Public Health and Health Services
 $34,875      $71,250      $72,508    $73,813      $37,534                $289,980    Basic Science      Epidemiology hepatitis C virus
           $3,617,780   $3,686,518 $3,750,361   $3,811,741 $3,811,741   $18,678,141                      Infectious Diseases
                                                                                      Clinical Medicine and Science HIV-AIDS
$176,340    $180,157     $183,578                                         $540,075                       Hepatology
                                                                                      Clinical Medicine and Science antiviral therapy
$115,800    $212,985     $211,724                                         $540,510                       Hepatology
                                                                                      Clinical Medicine and Science Cytokine
 $58,875      $60,125      $61,267    $62,370     $63,430                 $306,067                       Clinical Sciences not abuse and
                                                                                      Clinical Medicine and Science Alcoholelsewhere c
 $32,003      $32,628      $35,750                                        $100,381                       Hepatology
                                                                                      Clinical Medicine and Science exercise physiology
$181,035    $143,239     $145,959                                         $470,233                       Gastroenterology mediated immu
                                                                                      Clinical Medicine and Science Celland Hepatology
$174,800    $178,571     $181,962                                         $535,333    Basic Science      Hepatology hepatocytes and ch
$107,550    $121,039                                                      $228,589                       Gastroenterology
                                                                                      Clinical Medicine and Science Hepatitis B
 $32,003      $32,628     $35,750     $18,415                             $118,796    Basic Science                     hepatitis C
                                                                                                         Infectious Diseases
 $32,003      $32,628                                                       $64,631                      Hepatology
                                                                                      Clinical Medicine and Science antiviral
              $86,250     $87,508     $89,083     $90,598                 $353,439                       Infectious Diseases
                                                                                      Clinical Medicine and Science Immunological chan
$177,500   $180,871   $184,091                                               $542,462    Basic Science                     Antibody
                                                                                                            Medical Virology
$149,175   $152,008   $154,716                                               $455,899    Basic Science                     Fc Receptors
                                                                                                            Infectious Diseases
$154,275   $177,477   $165,290                                               $497,041                       Medical Virology
                                                                                         Clinical Medicine and Science hepatitis C virus
$168,249   $190,749   $209,091                                               $568,088                       Gastroenterology and C virus
                                                                                         Clinical Medicine and Science hepatitisHepatology
 $53,438    $72,508    $73,813    $75,068    $18,767                         $293,594                       Infectious Diseases
                                                                                         Clinical Medicine and Science HIV-HBV co-infectio
$100,686    $95,166    $81,448    $82,833                                    $360,133                       Gastroenterology and
                                                                                         Clinical Medicine and Science cirrhosisHepatology
 $22,677    $24,750    $25,327                                                 $72,754   Basic Science                     Cellular
                                                                                                            Cellular Immunology immunity
$136,175   $128,368   $130,639                                               $395,182    Public Health      Epidemiology hepatitis C
$500,000   $500,000   $509,000   $517,653   $517,653                        $2,544,306                      Clinical Sciences not elsewhere
                                                                                         Clinical Medicine and Science Aboriginal health c
           $299,188   $304,382   $309,556   $309,556                        $1,222,683                      Health         Addiction
                                                                                         Health Services Researchand Community Services
           $197,112    $54,068                                               $251,179    Public Health                     Indigenous Australi
                                                                                                            Public Health and Health Services
           $196,156   $199,666   $203,041                                    $598,864    Basic Science                     viral
                                                                                                            Medical Virology glycoproteins
            $24,750    $25,110    $26,479                                      $76,339   Public Health      Epidemiology cohort studies
            $24,750    $25,110    $26,479                                      $76,339   Public Health                     Prison populations
                                                                                                            Public Health and Health Services
           $114,128   $116,182   $118,157   $118,157   $118,157              $584,783    Basic Science                     Chronic hepatitis C
                                                                                                            Medical Virology
            $35,750    $36,286    $38,079                                    $110,115    Basic Science                     Hepatic Fibrosis
                                                                                                            Gastroenterology and Hepatology
           $152,339   $155,079   $157,714                                    $465,133    Public Health                     Economic evaluatio
                                                                                                            Health and Community Services
           $275,714   $275,468   $269,586                                    $820,767    Public Health                     cohort studies
                                                                                                            Public Health and Health Services
            $72,508    $73,813    $75,068    $75,068                         $296,457    Public Health                      Torres Strait Island
                                                                                                            Aboriginal andAboriginal and Torr
            $72,508    $73,813    $36,240    $56,301    $75,068              $313,930    Basic Science                     Chronic Infection
                                                                                                            Medical Virology
            $18,647    $25,110    $13,525                                      $57,282   Public Health                     Epidemiology
                                                                                                            Public Health and Health Services
            $96,040    $97,769    $99,431    $99,431                         $392,670                       Infectious Diseases
                                                                                         Clinical Medicine and Science Chronic viral infecti
           $119,678   $495,725   $593,976   $504,153   $474,905 $371,709    $2,560,145   Public Health      Epidemiology injecting drug use
                      $108,142   $109,981   $109,981   $109,981              $438,084    Basic Science      Innate Immunityvaccine biology
                      $184,390   $177,172   $197,878                         $559,440                       Gastroenterology and Hepatology
                                                                                         Clinical Medicine and Science liver disease
                       $62,370    $63,430    $63,430    $63,430   $63,430    $316,090                       Medical and liver
                                                                                         Clinical Medicine and Science Health Sciences not
                       $99,263   $100,951   $100,951                         $301,164                       Medical Virology
                                                                                         Clinical Medicine and Science hepatitis B virus
                      $167,216   $166,563                                    $333,779                       Infectious Diseases
                                                                                         Clinical Medicine and Science hepatitis C virus
                      $137,161   $139,493   $139,493                         $416,147    Basic Science                     virus
                                                                                                            Medical Virology pathogenesis
                      $187,637   $175,297   $159,767                         $522,701                       Gastroenterology and Hepatology
                                                                                         Clinical Medicine and Science hepatology
                      $166,852   $169,689   $169,689                         $506,230                       Gastroenterology and Hepatology
                                                                                         Clinical Medicine and Science hepatocellular carc
                       $86,261    $82,551    $82,551                         $251,364    Basic Science      Biostatistics biostatistics
                      $356,278   $369,789   $369,789                        $1,095,855                      Health         hepatitis Services
                                                                                         Health Services Researchand Community C infection
                       $36,286    $19,290                                      $55,576                      Gastroenterology and Hepatology
                                                                                         Clinical Medicine and Science clinical research
                       $25,110    $25,979    $26,479                           $77,567   Basic Science                     human immunodefi
                                                                                                            Medical Virology
                       $36,286    $37,579    $38,079                         $111,945                       Medical Virology
                                                                                         Clinical Medicine and Science hepatitis B infection
                                          $36,286      $37,579    $38,079                                $111,945                      Infectious Diseases
                                                                                                                    Clinical Medicine and Science hepatitis C virus
                                          $36,286      $38,079                                            $74,365                      Immunogenetics (incl. C infection
                                                                                                                    Clinical Medicine and Science hepatitisGenetic Im
                                                      $223,633   $223,633   $223,633                     $670,900   Basic Science                     hepatitis C virus
                                                                                                                                       Medical Virology
                                                      $158,876   $169,046   $163,961                     $491,882   Basic Science                     viral immunity
                                                                                                                                       Biochemistry and Cell Biology not
                                                      $130,891   $125,806   $120,085                     $376,782   Public Health                     qualitative research
                                                                                                                                       Health Promotion
                                                      $121,425   $216,687   $191,898 $163,920            $693,930                      Medical Virology
                                                                                                                    Clinical Medicine and Science hepatitis B infection
                                                      $156,389   $156,389   $156,389                     $469,168                      Medical Virology
                                                                                                                    Clinical Medicine and Science hepatitis C virus
                                                      $106,526   $106,526   $106,526 $106,526 $106,526   $532,628                      Infectious Diseases
                                                                                                                    Clinical Medicine and Science hepatitis C infection
                                                      $114,413   $114,413   $114,413                     $343,238   Basic Science                     hepatitis C virus
                                                                                                                                       Gastroenterology and Hepatology
                                                      $163,966   $163,966   $163,966                     $491,897                      Medical Molecular Engineering
                                                                                                                    Clinical Medicine and Science Aboriginal child of
                                                       $99,431    $99,431    $99,431 $99,431             $397,724   Public Health                     hepatitis C virus
                                                                                                                                       Public Health and Health Services
                                                       $37,618    $37,618    $38,118                     $113,353   Public Health      Epidemiology hepatitis B virus
                                                                  $37,618    $38,118                      $75,735                      Cancer Diagnosis
                                                                                                                    Clinical Medicine and Science hepatocellular carc
                                                       $28,213    $37,618    $38,118   $9,404            $113,353   Basic Science      Innate Immunityhepatitis B infection
                                                      $211,209   $211,209                                $422,418   Basic Science                     interferon-alpha (IF
                                                                                                                                       Immunology not elsewhere classif

$7,943,971   $11,993,089   $10,595,521 $9,936,668 $10,524,050 $8,706,953 $2,296,197 $814,420 $106,526 $95,266,182
    59           58             52         50         53          34         17        6        1
Research Research Research Research   Health   Health   Health   Health   Health              Media
                                                                                     Status
  KW 2     KW 3     KW 4     KW 5     KW 1     KW 2     KW 3     KW 4     KW 5                Summary
                                                                                   Closed                 END
                                                                                              Media Summary not available
                TRACING A
VARIANTSCONTACT VIRULENCENALYSTS                                                   Closed                 END
                                                                                              Media Summary not available
         GENOTYPES              CELLULARVIRAL
                                         IMMUNITY
                     RECOMBINANT PEPTIDES PERSISTENCE                                                                  Closed                         END
                                                                                                                                     Media Summary not available
                     INFLAMMATION
                                VIRAL
         IMMUNOPATHOGENESIS CLEARANCE   CHEMOKINES                                                                     Closed                         END
                                                                                                                                     Media Summary not available
                     HEPATOCYTES
         RESOLUTION OF INFECT           CYTOKINES
                                AGE-RELATED EFFECTS                                                                    Closed                         END
                                                                                                                                     Media Summary not available
                     REPLICATION
         MOLECULAR EVENTS       CONTROL MECHANISMS                                                                     Closed                         END
                                                                                                                                     Media Summary not available
                     CHROMATIN
         MINICHROMOSOME NUCLEOSOMES     TRANSCRIPTION                                                                  Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
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on Systems (incl. Surveillance)                                                                                        Closed                         END
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on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
                                                                                                                       Closed                         END
                                                                                                                                     Media Summary not available
         VIRUS       RIBOZYMESTRUCTURE       ANTIGEN                                                                   Closed                         END
                                                                                                                                     Media Summary not available
                                                                                                                       Closed                         END
                                                                                                                                     Media Summary not available
                     VIRAL
         POLYMERASE ENVELOPE PROTE            B VACCINE
                                  HEPATITISANTIVIRALS                                                                  Closed                         END
                                                                                                                                     Media Summary not available
on Systems (incl. Surveillance)                                                                                        Closed                         END
                                                                                                                                     Media Summary not available
                     IMMUNOTHERAPY DENDRITIC CELLS
         VIRUS INFECTION IMMUNE PERTURBATION                                                                           Closed                         END
                                                                                                                                     Media Summary not available
                     NATURAL CYTOTOXIX T MICE
         INTERFERON-ALPHAKILLER CELLS CELL   SCID                                                                      Closed                         END
                                                                                                                                     Media Summary not available
                     LATEX ALLERGENS
         T-CELL EPITOPES B-CELL EPITOPES                                                                               Closed                         END
                                                                                                                                     Media Summary not available
                     HUMORAL CELLULARDNA IMMUNIZATION
         PROTEIN PROCESSING       IMMUNE RESPOIMMUNE RESP                                                              Closed                         END
                                                                                                                                     Media Summary not available
                     WOMEN'S INJECTING DRUG USE HEALTH CAR
         ETHNIC HEALTH            HEALTH ACCESS TO                                                                     Closed                         END
                                                                                                                                     Media Summary not available
         PREVELANCE  CHRONIC CARRIAGE                                                                                  Closed                         END
                                                                                                                                     Media Summary not available
                     VIRAL CLEARANCE
         IMMUNOPATHOGENESIS                                                                                            Closed                         END
                                                                                                                                     Media Summary not available
         ASIAN WOMEN QUALITY OF LIFE                                                                                   Closed                         END
                                                                                                                                     Media Summary not available
                     OUTCOME OF AMPLIFICATION
         VIRAL PERSISTENCEPCRINFECTION                                                                                 Closed                         END
                                                                                                                                     Media Summary not available
                     CLINICAL
         PRIMARY INFECTIONVIRAL CLEARANCE                                                                              Closed                         END
                                                                                                                                     Media Summary not available
                     protection vaccine
         hepatitis C virus                               hepatitis C infection virus persistence
                                             virus-like particle      liver disease                                    Closed                         END
                                                                                                                                     The aim is to evaluate the efficiency of a virus-like particle (VLP) vaccin
                      of membranes induced by flavivirus infectionencephalitisin
                                  Helper system Kunjin Australian Creating a Targets for design of antiviral chemotherapy
                                             Roles replication induced membranesrelated flavivirus infections Closed
                                                         virus as hepatitis        and                                                                 the
         Biogenesis Flavivirus replication usingforof flavivirus ofa model C virusvitro replication system for hepatitis C virus Flaviviruses areENDagents of many mosquito-transmitted infections su
                     Pre-genomic  Reverse Transcription Design of antiviral therapies
                                             Viral recombination Liver disease
         Hepadnavirus replicationRNA packaging                                                Viral recombination Closed
                                                                                  Persistent hepatitis B virus infection                              END
                                                                                                                                     Title: Structure of hepadnaviral pre-genomic RNA. We aim to study the
                     social network
         molecular epidemiology analysis                               virus      prevention of transmission
                                                         Hepatitis C injecting drug use                                Closed                         virus
                                                                                                                                     The hepatitis C END (HCV) continues to spread among injecting drug u
                     viral fusion
         viral envelope protein assembly and topogenesis              hepatitis B targets for antiviral therapy of hepatitis B infection estimated 350 million people worldwide, and 250,000 in Australia, a
                                                         chronic viral infection virus infection                       Closed        An               END
             autoimmunity
Liver and hepatocytes tolerance transgenic mice Hepatocarcinomas
                                                             autoimmune and viral Hepatitis
                                                                         liver autoimmune diseases
                                                                                      transplantation         Closed                       that
                                                                                                                         It is well known ENDtolerance to liver allografts is more readily achieved
             Hepatitis C Men's Health
Health promotion                                Hepatitis C Injecting Drug Use
                                     Stigma of HCV                                    S                       Closed                       END
                                                                         Men's health ocial and Behavioural Research This study will identify the health and social support needs of men who
             suppression             transgenic mice
Liver and hepatocytes tolerance/autoimmunity    Hepatocarcinomas
                                                             autoimmune and viral Hepatitis
                                                                         liver autoimmune diseases
                                                                                      transplantation         Closed                       END
                                                                                                                         Acceptance of transplanted organs is currently achieved by treating the
             Pathogenesis of remodelling and fibrosis, cirrhosis
                                                 extracellular matrix Hepatitis B Hepatitis C hepatocellular carcinoma
                                                             Cirrhosis
Hepatic stellate cells tissuechronic hepatitis, Chronic hepatitis                                             Closed                       END
                                                                                                                         Chronic liver diseases, particularly those caused by Hepatitis B virus an
             inflammation
gene expression profiling                                    chronic hepatitis
                                                autoimmune hepatitis hepatitis C virus infection carcinoma
                                                                                      hepatocellular cirrhosis
                                                                                                   liver      Closed                       END
                                                                                                                         The incidence of hepatitis C virus (HCV) infection is rapidly increasing i
             Hepatitis C injecting drug clearance
                          virus      Viral
Exposed seronegative Thalassaemia users                                                                       Closed                       END
                                                                                                                         Media Summary not available
             Transcytosis iral pathogenesis
Polarized epithelia      V           Virus release
                                                Chronic hepatitis B hepatitis C transmitted Viral infections
                                                             Chronic                               hepatitis Closed
                                                                         Enterically Viral hepatitis                                       END
                                                                                                                         The viruses causing hepatitis in man must cross specialised cell layers
                                                                                                              Closed                       END
                                                                                                                         Media Summary not available
             fusion
Membrane Viral glycoproteins                                 Hepatitis C Hepatocelullar carcinoma
                                                                          virus infection
                                                Chronic disease caused by hepatitis C virus infection         Closed                       END
                                                                                                                         Hepatitis C virus (HCV), the main cause of of post-transfusion and com
             Qualitative research
Illness prevention and health education                      HIV         Hepatitis C Injecting drug use
                                                Blood borne communicable diseases                             Closed                       make
                                                                                                                         This project will END a direct and major contribution to Hepatitis C pre
             Cytopathic Hepatitis               Extrahepatic disease Viral hepatitis
Altered viral phenotypevariants B virus infection            Liver disease                                    Closed                       END
                                                                                                                         The human hepatitis B virus (HBV) is a member of the hepadnavirus fa
             DNA         Hepadnavirus infectionAntiviral therapy
Antiviral therapy vaccination        Immune therapy          Chronic liver diseaseB virus infection
                                                                         Hepatitis                            Closed                       END
                                                                                                                         Hepatitis B virus (HBV) causes acute and persistent (chronic) infection
             hepatocarcinogenesis
                         hepatocyte
TGF beta type III receptor                                               liver fibrosis
                                                hepatitis hepatocarcinogenesis metastasis                     Closed                       END
                                                                                                                         The transforming growth factor-beta (TGF-beta) family is a group of mu
             Hepatitis C Immunopathogenesis
Gene Expression           Virus      Liver Transplantation                                                    Closed                       END
                                                                                                                         Media Summary not available
             virus replication
recombinant baculovirus                                                               liver diseaseiral
                                                                                                   v
                                                cirrhosis hepatitis C hepatocellular carcinoma hepatitis      Closed                       cause
                                                                                                                         HCV is a major END of liver disease and around 200 million people ar
             Hepatitis Illict drugs Social determinants
Harm reduction                                                                                                Closed                       END
                                                                                                                         Media Summary not available
             virus       Therapeutics
Hepatitis B Human Immunodeficiency Virus AIDS                Acute Hepatitis
                                                                         Cirrhosis Hepatocellular carcinoma
                                                                                                   Liver transplantation
                                                                                                              Closed                       END
                                                                                                                         There are a number of patients throughout Victoria that are co-infected
              Virus      Oxidative stress
                                     Viral      Disease Hepatitis C related liver disease Therapeutic Intervention, new targets individuals infected with hepatitis C virus (HCV) show a
                                                                                      Therapeutic Intervention, antioxidants majority of END
Hepatitis C Hepatocellular Carcinoma Pathogenesis pathogenesis Hepatocellular Carcinoma                       Closed     The
lamivudine replication fitness                                                                                Closed                       END
                                                                                                                         Media Summary not available
             hepatitis C
hepatic fibrosis                                             hepatitis C hepatocellular cancer primary biliary cirrhosis Hepatic fibrosis ENDcommon response to chronic liver injury, during wh
                                                hepatic fibrosis                      liver transplantation Closed                          is a
             Induction of anti-HCV immune response
                                                Development of HCV vaccine
Development of chimeric virus-like particles (VLPs)                      Immunisation procedures based on liver disease
                                                                                                              Closed     Hepatitis         END
                                                             HCV: a major human pathogen inducing severevirus-like particles C virus (HCV) is a major causative agent of chronic liver disea
hepatitis obesity        steatosis treatment                                                                  Closed                       END
                                                                                                                         Media Summary not available
Hepatitis Liver Cancer   Nutrition Osteoporosis                                                               Closed                       provide new information to improve clinical outcomes fo
                                                                                                                         This Centre will END
             Risk factors
Immune response                      Viral
                         Transmission quasispecies C Incarceration
                                                Hepatitis                Injecting drug use                   Closed                       END
                                                                                                                         Hepatitis C (HCV) affects approximately 200,000 Australians, of whom
Health Care experiences                                                                                       Closed                       END
                                                                                                                         Media Summary not available
             Discrimination in providers settings people with hepatitis C
                         Health careHealth careinjecting drugs
                                       care      for
Discrimination by health carehealth for people Dental careHepatitis C Injecting drug use
                                                                                      Nursing                 Closed
                                                                                                   Primary health care                     END
                                                                                                                         Hepatitis C is now the leading communicable disease in Australia and s
                         young people
hepatitis C risk practices                                                                                    Closed                       END
                                                                                                                         Media Summary not available
              virus      Platform delivery
                                     Vaccine
Hepatitis C Modified virus-like particles of foreign epitopes                                                 Closed                       END
                                                                                                                         Media Summary not available
             L
Hepatocytes iver                                Chronic      Chronic liver injury
                         Nonalcoholic steatohepatitis liver disease Hepatitis Hepatocellular injury Closed                                 END
                                                                                                                         Nonalcoholic steatohepatitis (NASH) is the commonest cause for liver d
             liver regeneration
inflammatory cytokinesliver stem cells          alcohol      cancer      liver diseaseiral hepatitis
                                                                                      v                       Closed                       END
                                                                                                                         Maintaining liver function is essential for health, and compromising this
             hepatitis C immunology
cellular immune response             liver                                                                    Closed                       END
                                                                                                                         Media Summary not available
                         knowledge risk beliefs
                                     and
Hepatitis B health services utilisation factors                                                               Closed                       END
                                                                                                                         Media Summary not available
                         Tolerance Transplantation
Hepatitis T Lymphocytes Transgenic Mice                                                                       Closed                       END
                                                                                                                         Media Summary not available
HGV          HIV         Infect                                                                               Closed                       END
                                                                                                                         Media Summary not available
             reproduction            women's health
qualitative research service utilisation        contraception addiction
                                                             drug        hepatitis C                          Closed                       growing health concern, with 1% of the Australian popu
                                                                                                                         Hepatitis C is a END
Hepatitis B Vaccine Development Virus-like particle
                         Viral immunity                                                                       Closed     The small envelope protein of hepatitis B virus (HBsAg) can self-assem
                                                                                                                                           END
                          function
           hepatic cellhepatology peptidases tissue remodelling andLiver caused matrix inflammation fibrosis
                                                                Chronic disease diseases hepatitis C virus infection
                                                                              extracellular by
                                                                                          cirrhosis                liver      Closed                     END
                                                                                                                                        Chronic liver diseases, particularly those caused by autoimmune disea
                                       analogues Replication fitness
           Hepatitis B Nucleoside Precore mutation                                                                            Closed                     END
                                                                                                                                        Media Summary not available
                                                   fusion       flavivirus hepatitis C Virus infection
           flavivirus hepatitis C membrane virus entry and replication                    virus                               Closed                     END
                                                                                                                                        Hepatitis C Virus infects approximately 200 million people world-wide a
                         injection international health
           injecting drug use safety                                                                                          Closed                     END
                                                                                                                                        Media Summary not available
                         IDU
           Blood-borne virus          prevention                                                                              Closed                     END
                                                                                                                                        Media Summary not available
                         extracellular vitro and tissue of gene products
                                                   liver disease
           dipeptidyl pepidases inmatrixdefinciency remodelling                                                               Closed                     END
                                                                                                                                        Media Summary not available
           ethnography                public       s
                         injecting drug use healthexual health  blood borne communicablecontextsexual health
                                                                             injecting drug use
                                                                                          risk diseases
                                                                                                      s                       Closed
                                                                                                                   young people                          END
                                                                                                                                        National drug surveys and surveillance systems have detected sharp in
           hepacivirushepatitis viroporin virus replication                                           liver disease
                                                                cirrhosis hepatitis hepatocellular carcinoma                  Closed                     END
                                                                                                                                        Hepatitis C virus is a major medical problem in Australia and many othe
           hepatitis C immune response              study       epidemiology
                                      longitudinalviral persistence          genetic testing
                                                                                          hepatitis C virus infection persistence
                                                                                                      immune responses Closed
                                                                                                                   viral                                 virus
                                                                                                                                        The hepatitis C END (HCV) is a major public health problem affecting o
                         ethnography
           blood borne disease risk environment                                                                               Closed                     END
                                                                                                                                        Media Summary not available
           Viral immunityimmunopathology                                                                                      Closed                     END
                                                                                                                                        Media Summary not available
                                      medical      patient
           adherence injecting drug use treatment recruitment                                                                 Closed                     END
                                                                                                                                        Media Summary not available
                         escape mutants
           cytotoxic T lymphocytes    hepatitis C leucocyte membrane molecules disease progression the immuneClosed
                                                                HCV related pathogenesis
                                                                             HLA typing                                        system
                                                                                                      evasion of viral persistence                       END
                                                                                                                                        Over 200,000 Australians are infected with the Hepatitis C Virus (HCV)
           HIV           Hepatitis fibrosis                                                                                   Closed                     END
                                                                                                                                        Media Summary not available
epatitis C                                                                                                                    Closed                     END
                                                                                                                                        Media Summary not available
           drug treatment             pegylated interferon
                         injecting drug use                                                                                   Paying                     END
                                                                                                                                        Media Summary not available
                         hepatic steatosis
           hepatic fibrosis           hepatocyte proliferation  NAFLD        hepatitis C nonalcoholic steatohepatitis
                                                                                                      obesity                 Closed                     Fatty
                                                                                                                                        Lay DescriptionEND liver (steatosis) is important because it increases
                         hepatic steatosis
           hepatic fibrosis           hepatitis C hepatocyte proliferation                                                    Closed                     END
                                                                                                                                        Media Summary not available
                          fibrotic progression Stellate cell biology fatty mechanisms of hepatic fi
                                      Pathogenesis of non-alcoholic and liver disorder
           Hepatitis C Pathogenesis of autoimmune hepatitis                                                                   Closed                     END
                                                                                                                                        In humans, chronic liver diseases cause cirrhosis of the liver in some b
           Hepacivirus                             Hyperlipidemia
                         Hepatitis C Hepatitis viruses                                                                        Closed                     END
                                                                                                                                        Media Summary not available
                         Steatosis body composition
           Insulin Restistance                     viral genotype                                                             Closed                     END
                                                                                                                                        Media Summary not available
           Immune evasion             Viral glycoprotein function            Development of chronic HCV infection
                                                                                          HCV
                         Neutralizing antibody responses Ability to clear HCV infectioninfection                              Closed                     END
                                                                                                                                        Hepatitis C virus is a major human pathogen infecting 200 million peop
                         H            Preclinical immunogenicity
           Clinical trials epititis C virus        Vaccines                                                                   Paying                     END
                                                                                                                                        This research will advance the development of a novel vaccine strategy
                         Virus        Seroprevalence
           Hepatitis B Mathematical model molecular virology                                                                  Closed                     END
                                                                                                                                        Media Summary not available
                         Hepatitis C InteractionsPharmacogenetics thedrug hypersensitivity reaction
           HIV vaccine development                   between HIV and of human host immune
                                       disease pathogenesis                                                                   Paying                     END
                                                                                                                                        The Centre for Clinical Immunology and Biomedical Statistics (CCIBS)
           chemokines                 interferon microarray
                         hepatitis C virus                                                                                    Closed                     END
                                                                                                                                        Media Summary not available
                         Immunisation Population health
           Health Policy and Sevices evaluation    Prevention Hepatitis B Hepatitis B Immune response
                                                                                          carrier mothers
                                                                                                      Indigenous health       Closed                     END
                                                                                                                                        Hepatitis B virus (HBV) is transmitted by blood exposure or sexual cont
                         Hepatitis C virus replication
                                                   oxidative stress
                                                                alcoholic liver disease hepatic
                                                                             gene
           Hepatic Stellate Cells alcoholand anti-viral action of interferon expression fibrosis hepatitis replication
                                                                                                      viral        viral      Closed                     END
                                                                                                                                        Liver disease caused by alcohol consumption and hepatitis C virus (HC
           chemokines                 transcriptional regulation
                         gene expression           viral hepatitis
                                                                Hepatitis C hepatitis inflammation
                                                                              virus                   liver                   Closed                     END
                                                                                                                                        The majority of individuals infected with hepatitis C virus (HCV) show a
                          virus
           Hepatitis C Inflammation   Liver                                  Hepatitis infection
                                                                Chronic liver injury C Inflammatory mediators and the liver   Closed                     END
                                                                                                                                        The majority of patients who become infected with hepatitis C virus (HC
                                      social
           ethnicity injecting drug useresearch    treatment                                                                  Closed                     END
                                                                                                                                        Media Summary not available
           Liver disease              Obesity
                         Metabolic syndrome Steatosis                                                                         Paying                     END
                                                                                                                                        Media Summary not available
           immunotherapy              virology                  DNA
                         vaccine development virus-like particleand VLP Vaccinesurface antigen
                                                                             hepatitis B immunity-cellular
                                                                                                      immunotherapy           Closed
                                                                                                                   vaccine vectors                       END
                                                                                                                                        Many kinds of cancer and infections display unique proteins which the b
                         Hepatitis C Heptatis progression Chronic hepatitis C
           Hepatic fibrosis            disease C Viral hepatitis             Cirrhosis Hepatitis                              Closed                     END
                                                                                                                                        Hepatitis C virus (HCV) infection is a major cause of liver disease and a
                         Immunity toVaccine development, Diagnostic Assay
                                       infection
           Diagnostic tests and procedures vaccine technology                                                                 Paying                      exploiting basic and applied research on hepatitis virus
                                                                                                                                        I am a virologistEND
                         liver
           infectious disease                                                immune priming
                                                                cell mediated immunityimmune response                         Closed                      who
                                                                                                                                        Most individualsEND are infected with hepatitis C virus (HCV) develop
             viral
protein structureglycoproteins
                           virus entry and replication
                                        virus receptors
                                                     Hepatitis C understanding virus-host interactions
                                                                              viral infection                       Closed                      END
                                                                                                                               Hepatitis C virus (HCV) infects approximately 3 % of the global human
viral fusion virology of hepatitis B virus                        hepatitis B virus B virus
                                                                              liver infection
                                                     chronic carriers of hepatitis cancer                           Closed                      END
                                                                                                                               Three hundred and fifty million people worldwide and 250,000 in Austra
             m
biochemical olecules tiggers                                                                                        Paying                      END
                                                                                                                               Media Summary not available
                           Viral fusion
Hepatitis C Receptor binding                                                                                        Paying                      END
                                                                                                                               Media Summary not available
             Immunopathogenesis
Cellular immunology Viral clearance                                                                                 Paying                      END
                                                                                                                               Media Summary not available
             fusion
Membrane Viral glycoproteins                                                                                        Paying                      END
                                                                                                                               Media Summary not available
             Virus-like particle C influenza Development
                           delivery                               Hepatitis C Infection influenza strategy
                                                                               and and Vaccine
Vaccine development, hepatitis of B-cell and CTL epitopes of hepatitis C B control vaccine                          Closed                      END
                                                                                                                               For the induction of good immune responses, antigens should be delive
             Hepatitis C Humoral Immunity
Diagnostic Test             Virus Infection          Antibody Diagnostic Assay                          Immune Response
                                                                              Hepatitis C Humoral Immunology Closed            The prevalenceENDof Hepatitis C in Australia has been estimated at 242 0
             HepatocyteHistologicalproliferation
Cytokine mediated effects                techniquesHepatocellular carcinoma
                            death and Inverse nested PCR Liver disease        Resolution of hepatitis B virus infection
                                                                                            Therapy for chronic infection
                                                                                                                    Closed                      END
                                                                                                                               Though vaccination has had a major impact on the number of persons
             Humoral and cellular immunity
                                        Recombinant
Duck hepatitis B virus Prime-boost vaccination fowlpoxviruses hepatitis B virus disease Vaccine development Hepatitis B virus (HBV) causes acute and chronic infection leading to s
                                                     Antiviral therapy
                                                                  Chronic                   Immunotherapy
                                                                              Chronic liver infection               Closed                      END
             In            Inverse      Viral persistence
Hepatocytes situ hybridization nested PCR Chronic hepatitis B virus infection Viral hepatitis
                                                                  Cirrhosis ofHepatocellular carcinoma
                                                                               the liver                            Closed     Infection with the hepatitis B virus (HBV) can lead to either acute resolv
                                                                                                        Viral-induced cancer/oncogenesis        END
             synthetic lipopeptides
epitope mapping                                                               vaccine
                           vaccine development hepatitis C infectious diseases development  viral immunity          Closed                      END
                                                                                                                               The parts of viruses, bacteria and of cancer cells that are recognised b
             clinical HIV  heapatitis with hepatitis HIV-AIDS; therapy
chronic hepatitis B;care of personC; hepatitis B; C                                                                 Paying                      END
                                                                                                                               I am infectious disease physician undertaking research on natural histo
             hepatic progenitor cells
hepatic fibrosis                                                  fatty liver hemochromatosis insulin resistance
                                                     chronic liver disease disease          hepatic     hepatitis C Closed                      END
                                                                                                                               Chronic liver diseases such as hepatitis C and obesity-related fatty live
Liver                                    mice
             Tolerance Transgenic Transplantation    Hepatocarcinomas
                                                                  autoimmune and viral Hepatitis
                                                                              liver autoimmune diseases
                                                                                            transplantation         Closed                      END
                                                                                                                               The liver has paradoxical properties: it is the site of effective immune re
             Chronic       HIV-AIDS, Immunology,
Anti-viral therapy hepatitis B Hepatitis B Viral persistence                                                        Paying                      END
                                                                                                                               I am an infectious diseases physician and basic scientist interested in t
             Innate Immunity            Toll-like    Hepatitis Virus Infection
Immunosuppression Signaling pathways receptors B Immunomodulation             Inflammation  Sepsis                  Paying                      END
                                                                                                                               Hepatitis B virus (HBV) infection is a major world-wide health problem,
              Liver DiseaseHepatic Stellate Cell
Cholestatic Hepatic Fibrosis            PaediatricsBiliary AtresiaCholangiopathy Fibrosis Liver Disease Hepatitis
                                                                              Cystic        Idiopathic Neonatal Paying
                                                                                                        Liver Transplantation This project investigates how decreased bile flow in children's liver dise
                                                                                                                                                END
hepatitis B liver cancer                                                                                            Paying                      cause
                                                                                                                               Hepatitis B can END liver failure and cancer and affects between 90,0
             Hepatitis C Interferon microarray Hepatitis C Host antiviral responseliver disease
Gene Expression             Virus                                 Virus       interferon therapy HCV                Paying                      END
                                                                                                                               The only treatment for hepatitis C is Interferon-ribavirin combination the
             diseases,infection control,chronic disease infectious
caused by hepatitis        hepatitis,influenza,reproduction,                                                        Paying                      END
                                                                                                                               I am an immunologist with a background in virology and peptide chemis
                           prevention vaccinationhepatitis B immunisation diseaserevention of infectious disease
hepatitis B injecting drug use                                                liver         p                       Paying
                                                                                                        substance use                           END
                                                                                                                               This randomised trial will examine strategies to increase hepatitis B vac
             Genetics Hepatitis C Neuroimaging
Chronic fatigue syndrome                                                                                            Paying                      END
                                                                                                                               I am a clinician-scientist studying the biological determinants of clinical
             Risk behaviour
Qualitative research Social determinants of health                                                                  Paying                      END
                                                                                                                               This project seeks to discover how and why some injecting drug users
             population genetics and evolution
immune response            proteasomes  statistics                                                                  Paying                      END
                                                                                                                               Two hundred million people are infected with the Hepatitis C virus. The
Hepatitis C immune responseimmunity vaccines                                                                        Paying                      END
                                                                                                                               There is an urgent need to develop therapies for treating and preventin
                           interferon signaling
hepatitis c insulin resistance          obesity      hepatitis c insulin resistance
                                                                              interferon - obesity treatment
                                                                                            ribavirin               Paying                      END
                                                                                                                               The development of vaccines and better treatments for HIV-AIDS and H
             Lifestyle Liver
Insulin resistance factors              Obesity      Hepatic insulin resistance
                                                                  Hepatitis C exercise trainingliver disease
                                                                                            fatty                   Paying
                                                                                                        obesity-metabolism                      END
                                                                                                                               The overall objective of this Research Project is to examine the mecha
             Clinical care of persons Alcohol C, Injecting drug use
                                        Hepatitis
Alcoholic liver disease Drug abuse, with hepatitis C                                                                Paying                      END
                                                                                                                               The two most common types of liver disease in Australia are chronic he
                           obesity
hepatitis c insulin resistance          pathogenesis                                                                Paying                      END
                                                                                                                               I am a gastroenterologist investigating novel treatment approaches for
                           Viral Immunology
Hepatitis C Liver transplantation                                 Cirrhosis Liver diseases transplantation Paying
                                                                                            Liver       Primary                Chronic hepatitis C (CHC) infection and obesity are conditions of increa
                                                     Chronic disease caused by hepatitis C virus infection hepatocellular carcinoma             END
             liver cell lineage commitment
                                        stem cells
inflammatory cytokinesliver progenitor cells cell therapychronic liver diseaseviral hepatitis, HBV and HCV          Paying                      END
                                                                                                                               Liver diseases associated with Hepatitis C, including liver failure and liv
                           Stem cells
Hepatitis C Liver progenitor cells Tissue regeneration                                                              Closed                      a serious health problem. Viral hepatitis, obesity and al
                                                                                                                               Liver disease isEND
             immune response
humoral immunology vaccine development  virus like particle                                                         Paying                      END
                                                                                                                               The infection rate of HBV is 20% in Chinese and 10% in Australian in p
                           prophylaxisviral immunology
hepatitis B liver transplantation                                                                                   Closed                      END
                                                                                                                               Hepatitis C virus (HCV) infects 3% of the world's population and causes
Perinatal transmission
             Viral hepatitis                                                                                        Paying     Hepatitis B virus (HBV) can cause long term health problems particular
                                                                                                                                                END
             Virus       viral fusion
Hepatitis C envelope glycoprotein                  acute hepatitis
                                                               chronic disease caused by hepatitis C virus infection
                                                                           development of HCV vaccine
                                                                                       prevention of infectious disease
                                                                                                    viral hepatitis
                                                                                                                 Paying                          END
                                                                                                                               The first stage of Hepatitis C Virus replication involves attaching to liver
HIV-AIDS NK cells macrophages                                  HIV         Hepatitis                immune dysfunction
                                                                                                                 Paying
                                      monocytes HAART-AIDS pathogenesis C Immune Reconstitution Disease This project will END                    determine how viruses prevent transmission of messag
            liver
infectious disease                                             immune response.
                                                   cell mediated immunityneutralising antibody                   Paying                          END
                                                                                                                               A successful vaccine for RNA viruses like HIV and hepatitis C (HCV) w
            liver
infectious disease       therapy                   cell mediated immunity
                                                               cell therapyimmune response.
                                                                                       neutralisingviral clearance
                                                                                                     antibody Paying                             END
                                                                                                                               It is possible to cure some patients with HCV infection but the current th
            hepatic fibrosis
drug resistance          hepatotoxicity                                                                          Paying                          END
                                                                                                                               Chronic hepatitis B (HBV) infection may cause serious liver disease in s
genetic polymorphismspharmacogenomics
            hepatitis C                                                                                          Paying        Chronic hepatitis C infection (CHC) causes liver failure, liver cancer an
                                                                                                                                                 END
            Innate
Hepatits C virus immunity                                                                                        Paying                          END
                                                                                                                               Hepatitis C virus (HCV) poses a major public health problem with ~200
            molecular epidemiology
                         sexual
men who have sex with men transmission acute hepatitis C       hepatitis C sexually transmitted infections       Paying                          END
                                                                                                                               Hepatitis C virus (HCV) is usually transmitted by blood-to-blood contact
            Viral hepatitis
Sexually transmitted infections                                                                                  Paying                          END
                                                                                                                               This proposed new CCRE will bring together the leading Australian inst
            Health       Hepatitis C Opioid dependence
Health outcomes policy and services evaluation                                                                   Paying                          END
                                                                                                                               Hepatitis C (HCV) treatment uptake remains extremely low in Australia
                         prison population
hepatitis C mathematical modelling                 Aboriginal chronic
                                      qualitative research Health hepatitis C delivery health issue
                                                                           service infection
                                                                                       social                    Paying                          END
                                                                                                                               Despite the availability of an effective treatment for hepatitis C and the
            virus receptors
virus entry and replication                                    Hepatitis C Virus replication
                                                   Chronic infection                                             Paying                          END
                                                                                                                               Hepatitis C Virus infects 3% of the world's population causing recurring
injecting drug use
            molecular epidemiology epidemiology
                         social netword hepatitis
                                      viral                                                                      Paying        The new influenza A (H1N1) outbreak in Australia occurred at the start
                                                                                                                                                 END
                         risk behaviour hepatitis
drug use health servcie utilisation   viral                                                                      Paying                           a leading cause of liver transplants, and affects an esti
                                                                                                                               Hepatitis C is isEND
            Innate Immunity
Infectious Diseases Interferon Virus Replication                                                                 Paying                          END
                                                                                                                               I am a molecular virologist researching the host response to hepatitis C
                          Apoptosis Liver Transplantation
Hepatitis C HepatocyteImmunosuppression                                                                          Paying                          END
                                                                                                                               Mast cells are important in immunity. Mast cells have been implicated in
            Health       Hepatitis C Mathematical  Chronic liver
                                                               Health outcomes
Health outcomes policy and services evaluationmodelling disease Health services        Hepatitis C Population Paying
                                                                                                     virus infection
                                                                                                                 health                           impact
                                                                                                                               To evaluate theEND of introducing hepatitis C virus (HCV) preventio
                         randomised controlled development of HCV vaccine drug use
hepatitis C injecting drug use                     trial
                                      vaccine preparedness hepatitis C injecting liver diseaserevention Paying
                                                                studies                             p                          disease           END
                                                                                                                 of infectious Injecting drug users (IDU) are a key target group for new vaccines desi
Blood borne viruses Health services access
            Health promotion                                                                                     Paying        Despite Australia’s successful hepatitis B vaccination campaign for infa
                                                                                                                                                 END
evasion of the immunevirus infection
            hepatitis C system                                                                                   Paying        Hepatitis C virus (HCV), a major cause of hepatitis and liver failure is a
                                                                                                                                                 END
            Injecting Population health
Infectious diseases drug use          Vaccines                                                                   Paying                          END
                                                                                                                               GSAO is an Australian anti-cancer drug that is currently being trialed in
HBV         HCV          Herpes viruses                                                                          Paying                            and
                                                                                                                               HIV, Hepatitis BEND Hepatitis C are major health issues, especially to i
hepatitis substance use  prison population health
                                      mental                   infectious diseases use
                                                   injecting drug use      substance prison population health
                                                                                                    mental       Paying        Injecting drug use (IDU) is a disproportionately large source of health a
                                                                                                                                                 END
            cytokine production hepatitis C infection vaccine technology
dendritic cell           bone marrow               adjuvant                viral immunity
                                                                                       dendritic cell
                                                                                                    hepatitis C Paying
                                                                                                                 infection                       END
                                                                                                                               Dendritic cells (DC) are rare cells that are crucial in response to infectio
            hepatic steatosis
hepatitis C infection antiviral agents                         h           hepatic steatosis
                                      cannabis liver diseaseepatitis C infection antiviral therapy               Paying                          END
                                                                                                                               Hormones related to cannabis help to regulate fat stores in the human
            lifestyle    metabolic syndrome disease C virus liver disease
hepatitis C infectionfactors          fatty liver hepatitis fatty          fibrosis    lifestyle factors         Paying                          END
                                                                                                                               The overall objective of my research activity is to examine in human su
            hepatocytes               viral
duck hepatitis B virus viral replication persistence
                                                   hepatitis B infection antiviral therapy
                                                               liver disease                        cell proliferation
                                                                                       paracetamol toxicity Paying                               END
                                                                                                                               Worldwide >360 million people have chronic hepatitis B virus (HBV) inf
            sequencing
drug resistance                                                drug therapy
                                                   hepatitis C infection resistance                              Paying                          END
                                                                                                                               Hepatitis C therapy in the future is likely to involve the use of Directly A
            chronic infection
                         T cells
human immunodeficiency virus (HIV)    cytokines chronic infection immunodeficiency virus B infection C Paying
                                                               human                   hepatitis hepatitis virus
                                                                           virus pathogenesis (HIV)                                              END
                                                                                                                               Our robust ability to mount an immune response and clear infections is
            liver disease             drug         liver
hepatitis C infection interferon (IFN) efficacy diseaseepatitis C infection (IFN)
                                                               h           interferon genetics                   Paying                            world
                                                                                                                               About 3% of theEND population is currently infected with hepatitis C v
            drug         liver
hepatitis B virus resistance disease                           liver cancerhepatocellular carcinoma
                                                   hepatitis B infection                                         Paying                          END
                                                                                                                               We aim to investigate the consequences of long-term therapy for hepa
             studies                  drug
associationgenomics vaccine design resistance      human leukocyte antigen (HLA)
                                                               hepatitis C virus immunodeficiency virus (HIV)
                                                                           human                                 Paying                            HIV
                                                                                                                               Viruses such asEND or Hepatitis B or C may escape detection, and hen
            prison population                      hepatitis C infection B infection drug use
hepatitis B infection prevention health services research      hepatitis injecting liver disease                 Paying                          C infection rates remain very high in some Australian p
                                                                                                                               Hepatitis B and END
                                                               prognosis               treatment complications
genomics proteomics translational research hepatitis C infection pharmacogenomics outcomes Paying                                                END
                                                                                                                               Patients undergoing treatment for hepatitis C must endure a treatment
            therapeutic target
chronic infection                                              human       immune modulation (HIV)
                                                                                       hepatitis hepatitis virus
                                                   chronic infection immunodeficiency virus B infection C Paying                                 END
                                                                                                                               Chronic infections produced by pathogens such as HIV, overwhelm our
drug resistance
            vaccination failure                    hepatitis B infection immunisation
                                                               drug resistance                                   Paying        “Antiviral drug-associated vaccine escape mutants” have the potential t
                                                                                                                                                 END
             blood-borne communicable
                          virology
human immunodeficiency virus (HIV) diseases                     human
                                                    hepatitis C virus immunodeficiency virus (HIV) diseases
                                                                            blood-borne communicable
                                                                                        virology                Paying                       END
                                                                                                                            Hepatitis C affects between 1-3% of Australians. Currently, there is no
single nucleotide polymorphism (SNP)
             interferon (IFN)                       hepatitis C infection non-responders
                                                                interferon interferon (IFN)                     Paying      An estimated 3% of the world’s population is infected with hepatitis C v
                                                                                                                                             END
glycoproteins                          receptor binding         vaccine
             antibody vaccine development chronic infection design          structure-function                  Paying                       END
                                                                                                                            Hepatitis C Virus infects 200 million people world-wide with over 200,00
             innate immunity
viral clearance           microrna interferon (IFN) dengue virusinfluenza virus
                                                                            hepatitis C virus                   Paying                       END
                                                                                                                            microRNAs (miRNAs) constitute a novel mechanism used by cells and
             prevention injecting drug use
hepatitis C virus                      relationships                                                            Accepted    Transmission ofENDhepatitis C among people who inject drugs occurs prim
             liver diseaseliver fibrosis
human immunodeficiency virus (HIV)     inflammation immunology                                                  Accepted                     END
                                                                                                                            Morbidity and mortality secondary to liver disease is greatly increased i
             virus        host/pathogen interaction disease
antiviral agents pathogenesis                       liver
                                       hepatitis C infection                                                    Paying                       END
                                                                                                                            Hepatitis C virus (HCV) is a serious viral pathogen that causes significa
             hepatitis C virus
clinical research         epidemiology health services research                                                 Paying                       END
                                                                                                                            The renewal of my Practitioner Fellowship will continue to facilitate an e
liver injury obesity      inflammation adiposity                                                                Accepted                     END
                                                                                                                            Presently, liver disease from chronic hepatitis C and obesity represents
                          hepatitis B virus
otitis mediaStreptococcus pneumoniae   vaccine development                                                      Paying                       END
                                                                                                                            Australian Indigenous children suffer abormally high levels of middle ea
             natural
injecting drug use history                          epidemiology
                          treatment access to health care                                                       Accepted                      majority of hepatitis C is acquired by injecting drug use
                                                                                                                            In Australia, theEND
             epidemiology              health literacy
hepatitis B infection molecular epidemiology                    health education
                                                    communication skills burden of disease                      Paying                       END
                                                                                                                            I am an Infectious Diseases doctor working with Hepatitis B in the Top
             hepatoma                               cancer      cancer
hepatocellular cancer liver cancercancer detection screening genetics fibrosis
                                                                            liver                   hepatitis Accepted
                                                                                        hepatitis C infection B infection                    END
                                                                                                                            Hepatocellular carcinoma (HCC) is the most common primary liver can
             fibrosis     stellate cells epatitis
human immunodeficiency virus (HIV)     h                                                                        Paying                       END
                                                                                                                            Liver related mortality is the commonest cause of non-AIDS death in HI
             hepatitis innate immunity
hepatitis B infection C infection immune response                                                               Accepted                     END
                                                                                                                            Despite recent advances in therapeutic options, chronic viral infections
NHMRC FUNDED RESEARCH INTO ALL VIRAL HEPATITIS ISSUES 2000/01-2011/12
Keywords: Hepatitis (reviewed for viral Hepatitis), HEP, HEP A, HEP B, HEP C, HEP D, HEP E, HAV, HBV, HCV, HDV, HEV, HGV, GBV-C
Report Run: 3 July 08/19 Mar 09/10 Mar 10/28 Feb 11/7 May 12
Sources: Extracted from NHMRC Databases -RGMS/ RMIS/GMS as at May 12
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with the disease area of Viral Hepatitis (all
Hepatitis) through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the research area in question
may be either immediate or be a longer term perceived benefit. This dataset was current as at 7 May 12 but is subject to change over time.
Summary of Expenditure: All Viral Hepatitis
   2000-01            $2,416,546 Actual Expenditure             52 grants
   2001-02            $2,632,876 Actual Expenditure             48 grants
   2002-03            $2,619,757 Actual Expenditure             46 grants
   2003-04            $2,640,865 Actual Expenditure             44 grants
   2004-05            $3,297,658 Actual Expenditure             45 grants
   2005-06            $5,095,481 Actual Expenditure             49 grants
   2006-07            $6,650,248 Actual Expenditure             59 grants
   2007-08            $7,581,089 Actual Expenditure             76 grants
   2008-09            $9,968,534 Actual Expenditure             70 grants
   2009-10          $11,294,311 Actual Expenditure              72 grants
   2010-11          $10,266,097 Actual Expenditure              67 grants
   2011-12          $10,230,361 Forecast Expenditure            62 grants
   2012-13            $9,615,499 Forecast Expenditure           54 grants
     Total          $84,309,322 As at Dec 12
  2013-14            $5,501,574 Forward commitments             34 grants
  2014-15            $1,555,309 Forward commitments             17 grants
  2015-16              $460,473 Forward commitments             6 grants
  2016-17                $53,263 Forward commitments            1 grant
      Total         $91,879,941 Incl out years
2 . Forward commitments funding data for out-years (ie beyond 2012) is subject to change when new grants are awarded in subsequent years

 Grant Id        CIA Full Name         Grant Type                      Grant Subtype                   Scientific Title         Simplified Title      Admin Institutution

   956084 Prof Ian Anderson            CARG                         ANCARD Project Grant                                     Developing a HIV Program Risk Reduction Health Service in the
                                                                                                                                                        Victorian in the Melbourne for IDU
                                                                                                  Developing a HIV and HepC Risk Reduction and HepCfor IDUAboriginalProgramKoori Commun
   967008 A/Pr Karen Vickery                                        Australian Clinical Research ECF
                                       Early Career Fellowships (Australia)                                                  Hepatitis B variation: a model of variation
                                                                                                                                                        University of Sydney
                                                                                                  Hepatitis B variation: a model of variation of molecular epidemiologyof molecular epidemiology
   967448 Mr Ricardo Lareu                                          Dora Lush Biomedical Scholarship of novel apoptosis-associated gene in tumour University gene in tumour
                                       NHMRC Postgraduate Scholarships                            Role                       Role of novel apoptosis-associated of Western Australia
977157   Dr George Marinos                                     Australian Clinical Research ECF immunopathogenesis The immunopathogenesisUniversity of New South Wales
                                  Early Career Fellowships (Australia)                       The                                                         infection
                                                                                                                           of chronic hepatitis c virus of chronic hepatitis c virus infection
980194   A/Pr Allison Jilbert     NHMRC Project Grants         Standard Project Grant                                     of hepadnavirus infection University of Adelaide
                                                                                             Mechanisms of resolution Resolution of duck hepatitis B virus infection
981447   Prof Eric Gowans         NHMRC Project Grants         Standard Project Grant                                     Hepatitis C virus replication
                                                                                             Molecular events of hepatitis C virus replication        Royal Children's Hospital, Brisbane
981683   Prof Stephen Locarnini   NHMRC Project Grants         Standard Project Grant                                     Examination minichromosome  Melbourne Health
                                                                                             Characterisation of the hepatitis B virusof the key intermediate in the hepatitis B virus life cycle
983604   Prof Jill COCKBURN       SRDC                         Hepatitis C                                                 compliance with improve compliance Newcastle
                                                                                                                                                      University of with skin penetration g/lines
                                                                                             An intervention to improveAn intervention toskin penetration g/lines in Tattooists, Beauty Thera
983608   Prof John Crofts         SRDC                         Hepatitis C                                                Peer testing for and testingMacfarlane a needle and syringe exchang
                                                                                             A pilot peer-based hepatitis C counselling Hepatitis C service atBurnet Institute for Medical Re
983610   Prof John Crofts         SRDC                         Hepatitis C                                                HCV education and Vietnamese IDUsBurnet Institute for Medical Re
                                                                                                                                                      Macfarlane
                                                                                             Prevention of HCV infection amongst IDUs of Vietnamese ethnicity
983615   Dr Alex Wodak            SRDC                         Hepatitis C                                                Encouraging drug injectors who cannot stopSouth use
                                                                                                                                                      University of New drug Wales
                                                                                             A feasibility study of non-injecting routes of administration (NIROA) among IDUs to shift to use
983618   A/Pr Gary Dowsett        SRDC                         Hepatitis C                                                Gay men, drug culture and Hepatitis C prevention
                                                                                                                                                      La Trobe University
                                                                                             Hepatitis C prevention among gay men who inject drugs in Melbourne's gay community
983619   A/Pr Michael Dunne       SRDC                         Hepatitis C                                                Quality with among people living with University of Technology
                                                                                                                                                      Queensland chronic Hepatitis C_infection
                                                                                             Quality of life among people livingof lifechronic Hepatitis C infection
983627   Prof Sandra Gifford      SRDC                         Hepatitis C                                                The and health needs of Deakin living with
                                                                                                                                                       of women living with Hepatitis
                                                                                             Identifying the social, personal health and well beingwomen University Hepatitis C C
983629   Prof Jeanette Ward       SRDC                         Hepatitis C                                                A their patients about needs, in general and Area Health Services
                                                                                                                                                      Sydney South practice
                                                                                             National surveys of GPs andnational study of hepatitis C outcomesWestpatterns of care
983633   Prof Susan Kippax        SRDC                         Hepatitis C                                                IDU - to injecting drug use among injecting South youth
                                                                                                                                                      University of New
                                                                                             Risks for Hepatitis C: Transition Data collection. Transition to urban and rural Wales
983641   A/Pr Wendy Loxley        SRDC                         Hepatitis C                                                Exploring testing injectingCurtinare tested for Technologyother blood
                                                                                                                                                       drug University of hep C and
                                                                                             Investigation of the process by which injecting drug users users for hepatitis and HIV/AIDS
983654   Dr Greg Rumbold          SRDC                         Hepatitis C                                                A national survey of hepatitis C risk practices amongDrug Centre
                                                                                                                                                      Turning Point Alcohol An injecting drug
                                                                                             A national survey of hepatitis C risk practices among injecting drug users: andoverview of risk
983657   Prof Susan Sawyer        SRDC                         Hepatitis C                                                Reducing transmission of Murdochpeer education strategy
                                                                                                                                                       HCV a Childrens Research Institute
                                                                                             Reducing transmission of HCV in high risk young people -in high-risk young people
987074   Dr A Dingley                                          CJ Martin (Biomedical) ECF The molecular structure and function of the Hepatitis delta virus of the Hepatitis delta virus ribo
                                  Early Career Fellowships (Overseas)                                                                                 University of Sydney
                                                                                                                          The molecular structure and function ribozyme
990657   Prof Andrew Lloyd        CARG                         ANCARD Project Grant                                       Transmission and clearance of HCVof New South primary
                                                                                                                                                      University
                                                                                             Modes of transmission, natural history and determinants of viral clearance in Wales hepatitis
990988   Prof Stephen Locarnini   NHMRC Project Grants         Standard Project Grant                                     Investigations into the of hepatitis ofHealth in hepatitis B virus se
                                                                                                                                                      Melbourne changes
                                                                                             Studies of polymerase/envelope protein variants significanceB virus resulting from antiviral tre
991357   A/Pr Rohan Jayasuriya    CARG                         ANCARD Project Grant                                       Study of Risk Behaviour in Injecting of Wollongong
                                                                                                                                                      University Drug Users Hepatitis C
                                                                                             Cohort Study of Risk Behaviour in Injecting Drug Users for transmission of for transmission of
991502   Prof Eric Gowans         NHMRC Project Grants         Standard Project Grant                                      immunotherapy associated with dendritic Hospital, Brisbane
                                                                                                                                                      Royal
                                                                                             Immunopathogenesis and Hepatitis C and dendritic cells Children'scells in HCV infection
997468   Dr Gerard MacQuillan                                  Medical                       Mechanisms of                Mechanisms of response University of Western Australia
                                                                                                                                                      and non-response (IFN-a) in chronic hep
                                  NHMRC Postgraduate Scholarships Postgraduate Research Scholarship response and non-response to interferon-alpha therapyto interferon-alpha ther
997494   Dr Michael Sutherland                                 Medical                       Characterisation             Characterisation of the human cellular the major latex allergen,to the
                                                                                                                                                      response to and humoral response HEV
                                  NHMRC Postgraduate Scholarships Postgraduate Research Scholarship of the human cellular and humoral Monash University
997607   Dr Fan Li                                             Dora Lush Biomedical Scholarship
                                  NHMRC Postgraduate Scholarships                                                         Hepatitis E virus and the immune responses Institute for Medical Re
                                                                                                                                                      Macfarlane Burnet induced by DNA immu
                                                                                             Hepatitis E virus capsid protein processing capsid protein processing and the immune respons
   459   Prof Sandra Gifford      NHMRC Project Grants         Standard Project Grant                                       Ethnographic Study of South- East Asian Women of HCV positive
                                                                                                                                                      Deakin and social
                                                                                             Bad Blood, Bad Livers: AnA Qualatative Study of the HelathUniversity NeedsLiving with hepa
  7087   A/Pr Margaret Hellard                                 Australian Clinical Research ECF
                                  Early Career Fellowships (Australia)                                                      NATURAL HISTORY OFMonash University
                                                                                                                                                         NATURAL HISTORY OF C IN A COHO
                                                                                             INVESTIGATION OF THEINVESTIGATION OF THECOMMUNITY ACQUIHEPCOMMUNITY A
  7443   Dr Charles Harvey                                     Dora Lush Biomedical Scholarship
                                  NHMRC Postgraduate Scholarships                                                         Correlation of immune responses to of New South Waleshepatitis C
                                                                                                                                                      University outcomes following
                                                                                             Correlation of immune responses to outcomes following immunotherapy in chronic immunothe
  8130   Dr Anouk Dev                                          Medical                       Factors affecting            Factors affecting the course of hepatitis C in
                                                                                                                                                      Monash University
                                  NHMRC Postgraduate Scholarships Postgraduate Research Scholarship the course of hepatitis C in South-East Asian women South-East Asian wom
  8154   Dr Marc Le Mire                                       Medical                       Persistence of               Persistence of duck hepatitis persistent infection
                                                                                                                                                      University DNA in transient & persistent in
                                  NHMRC Postgraduate Scholarships Postgraduate Research Scholarship duck hepatitis B virus DNA in transient &B virusof Adelaide
  8175   Dr Jeffrey Post                                       Medical                       Natural history              Natural C virus infection hepatitis C virus infection
                                  NHMRC Postgraduate Scholarships Postgraduate Research Scholarship of primary hepatitishistory of primary University of New South Wales
102421   Prof Eric Gowans         NHMRC Project Grants         Standard Project Grant                                     A vaccine for C virus.      Macfarlane Burnet Institute for Medical Re
                                                                                             A virus-like particle vaccine for hepatitis hepatitis C virus.
102481   Dr Jason Mackenzie       NHMRC Project Grants         Standard Project Grant                                     Where ultrastructure andUniversity Australian encephalitis and den
                                                                                                                                                        roles of induced membranes
                                                                                             Flavivirus replication - biogenesis,and how the viruses causing of Queensland
104892   A/Pr Allison Jilbert     NHMRC Project Grants         Standard Project Grant                                     Structure of RNA.           pre-genomic RNA.
                                                                                             Structure of hepadnaviral pre-genomichepadnaviral University of Adelaide
111701   Prof John Crofts         CARG                         ANCARD Project Grant                                       How do social molecular Macfarlane Burnet Institute the spread Re
                                                                                                                                                      epidemiology of the hepatitis C virus
                                                                                             Injecting drug users: social networks andnetworks of injecting drug users affect for Medical of
111710   Dr Elizabeth Grgacic     NHMRC Project Grants         Standard Project Grant                                     The ins and outs of hepatitisthevirus
                                                                                                                                                      of B enveloped hepatitis for Medical Re
                                                                                             Protein topogenesis and the assembly/disassembly Macfarlane Burnet InstituteB virus.
115030   Dr Patrick Bertolino     NHMRC Project Grants         New Investigator Grant                                     Role primary CD8+ in tolerance
                                                                                                                                                       activation and tolerance
                                                                                             Role of hepatocytes in inducingof hepatocytes T cellUniversity of Sydney
136917   Prof Sandra Gifford      NHMRC Project Grants         Standard Project Grant                                     Investigating the health and well being of men living
                                                                                                                                                      Deakin University
                                                                                             Identifying the social, personal and health needs of men living with hepatitis C. with hepatitis C
137841   Dr Patrick Bertolino     NHMRC Project Grants         Standard Project Grant                                     T cell suppression in transgenic mice Sydney
                                                                                                                                                      University of
                                                                                             Transgenic mice : a unique model to reassess specific T cell suppression
142606   Prof Geoffrey McCaughanNHMRC Project Grants         Standard Project Grant                                      Fibroblast Activation Protein and Liver Alfred
                                                                                                                                                     Liver Prince
                                                                                            The Role of Fibroblast Activation Protein in Chronic RoyalInjury Injury Hospital
142607   Prof Geoffrey McCaughanNHMRC Project Grants         Standard Project Grant                                      Pathogenesis of hepatitis Royal C virus associated liver
                                                                                                                                                     C virus infection
                                                                                            Novel approaches to the pathogenesis of chronic hepatitisPrince Alfred Hospital disease
145884   Dr Anthony Freeman                                  Medical                        Cellular immunity            Cellular immunity in hepatitis C exposedusers and Wales
                                                                                                                                                     University of uninfected injecting thalas
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship in hepatitis C exposed uninfected injecting drugNew South transfuseddrug us
149501   A/Pr David Anderson    NHMRC Project Grants                                        Polarized epithelia          How viruses get in and out viruses
                                                                                                                                                     Macfarlane
                                                             Standard Project Grant with Research Fellowshipand the natural history of hepatitis of the liverBurnet Institute for Medical Re
149534   A/Pr David Anderson                                 NHMRC Research FellowshipPolarized epithelia & the natural history of hepatitis natural history of hepatitis viruses
                                Established Career Fellowships                                                                                       Macfarlane Burnet Institute for Medical Re
                                                                                                                         Polarized epithelia & the viruses
156714   Dr Pantelis PoumbouriosNHMRC Project Grants         Standard Project Grant                                      Hepatitis C Virus entry. St Vincent's Institute of Medical Research
                                                                                            Molecular Mechanisms of How does Hepatitis C Virus infect cells?
157128   Prof Susan Kippax      NHMRC Project Grants         Standard Project Grant                                      Blood awareness in Hepatitis C prevention South education and he
                                                                                                                                                     University C prevention Wales
                                                                                            An analysis of "blood awareness" for the purposes of Hepatitisof New education
158010   A/Pr Allison Jilbert   NHMRC Project Grants         Standard Project Grant                                      Mutant strains of hepatitis B virus that Adelaide
                                                                                            Virulence determinants in hepadnavirus infection University of cause disease
158011   A/Pr Allison Jilbert   NHMRC Project Grants         Standard Project Grant                                      Treatments for hepatitis BUniversity of infection.
                                                                                                                                                      virus virus Adelaide
                                                                                            Combination antiviral and immune therapies for hepatitis Binfection
164815   Dr Kaye Stenvers       NHMRC Project Grants         Standard Project Grant                                       in normal receptor type livernormal and malignant liver growthactivi
                                                                                                                                                      in growth: Modulation of TGF-beta
                                                                                            TGF-beta receptor type III TGF-beta and malignantIIILudwig Institute for Cancer Research
165702   Dr Amany Zekry                                      Medical                        Immunopathogenesis and Immunopathogenesis andUniversity of Gene Virus Post Liver Transp
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                     Differential Sydney
                                                                                                                          Differential Gene Expression of Hepatitis C Expression of Hepatitis
191805   Prof Eric Gowans       NHMRC Project Grants         Standard Project Grant                                      Hepatitis C and approaches to
                                                                                                                                                     Macfarlane Burnet replication
                                                                                            The in vitro culture of hepatitis C virusculture and control the control ofInstitute for Medical Re
191820   Prof John Crofts                                    NHMRC Research FellowshipUncoupled Research Fellowship
                                Established Career Fellowships                                                                                       Macfarlane Burnet Institute for Medical Re
                                                                                                                         Uncoupled Research Fellowship
201700   Dr Joseph Sasadeusz NHMRC Project Grants            Standard Project Grant                                      Studies of                  Melbourne
                                                                                            Studies of HIV and HBV co-infection.HIV and HBV co-infection.Health
207817   Dr MICHAEL BEARD NHMRC Project Grants               New Investigator Grant                                      Oxidative Stress in HCV C Virus Liver Adelaide
                                                                                                                                                     University of Disease
                                                                                            Induction of Reactive Oxygen Species by Hepatitis Related and its Role in Liver Pathogenesis
209196   Mr Theo Gouskos                                     Dora Lush Biomedical Scholarship
                                NHMRC Postgraduate Scholarships                                                          Restoration of the development of compensatory mutations compe
                                                                                                                                                     University of Melbourne
                                                                                            Restoration of HBV replication fitness by HBV replication fitness by the development ofin the v
210109   A/Pr Julie Jonsson     NHMRC Project Grants         Standard Project Grant                                       the Renin-Angiotensin ofUniversity of Queensland
                                                                                                                                                      the Renin-Angiotensin
                                                                                            Investigation of the role of Investigation of the roleSystem in hepatic fibrosis.System in liver fibr
210232   A/Pr Hans Netter       NHMRC Project Grants         Standard Project Grant                                      Synthesis of virus-like particles immune variety of foreign epitopes
                                                                                                                                                     Monash University
                                                                                            Development of a HBV-specific carrier matrix to induce ancarrying aresponse against quasispe
210356   Dr Ingrid Hickman                                   Dora Lush Biomedical Scholarshiprole of obesity and nutrition in chronic hepatitis C and fattyof Queensland C and fatty liver
                                NHMRC Postgraduate Scholarships                             The                                                      University liver hepatitis
                                                                                                                         The role of obesity and nutrition in chronicdisease
219282   Prof Geoffrey Farrell                               Centre of Clinical Excellence Centre for Clinical Research Excellence to improve outcomes in chronic liver disease in chr
                                Centres for Research Excellence                                                                                      University of Sydney
                                                                                                                         Centre for Clinical Research Excellence to improve outcomes
222887   Prof Andrew Lloyd      NHMRC Project Grants                                        The HITS                       transmission, natural history and determinants of Wales prisoners
                                                                                                                                                     University of New hepatitis C in
                                                             Large Scale Clinical Trials Project Grant study: modes ofHITS: a prospective cohort study of primary South outcome from prim
222922   Dr Loren Brener                                     Public                         Health care                  Health C positive clients:University positiveSouth Wales
                                                                                                                                                      a study C health clients: a study
                                NHMRC Postgraduate Scholarships Health Postgraduate Scholarship workers and hepatitiscare workers and hepatitis of of New care experiencesof healt
229304   Prof Sandra Gifford    NHMRC Project Grants         Standard Project Grant                                      Discrimination, hepatitis C discrimination of people with hepatitis C in
                                                                                                                                                      in health care settings.
                                                                                            Discrimination or Discretion? Factors contributing toLa Trobe University
234428   Mr Paul Myers                                       Public                         A cross-national longitudinalcross-national risk practices and of HCV risk practices and health
                                NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                      University of Melbourne
                                                                                                                         A study of HCV longitudinal study health outcomes in homeless yo
237056                                                       Dora Lush Biomedical Scholarship
         Miss Patricia Vietheer NHMRC Postgraduate Scholarships                                                          Development virus particles hepatitis B virus particles as a hepatit
                                                                                                                                                     Monash University
                                                                                            Development of recombinant hepatitis Bof recombinantas a platform for the delivery of platform
253766   Prof Jacob George      NHMRC Project Grants         Standard Project Grant                                      NASH pathogenesis in man     steatohepatitis: Insights from human stud
                                                                                            Molecular and cellular pathogenesis of nonalcoholicUniversity of Sydney
254666   Prof George Yeoh       NHMRC Project Grants         Standard Project Grant                                      Factors which liver the growth and of Western Australia precursor
                                                                                                                                                     University development of liver
                                                                                            The role of TNF and its receptor family inaffectprogenitor cell proliferation and differentiation
262012   Dr David Bowen                                      CJ Martin (Biomedical) ECF Hepatitis C virus replication and immunity in the chimpanzee Institutethe Cancer Medicine an
                                Early Career Fellowships (Overseas)                                                                                  Centenary
                                                                                                                         Hepatitis C virus replication and immunity in of chimpanzee
262068   Dr Hani Tawk                                        Primary
                                NHMRC Postgraduate Scholarships Health Care Scholarship                                  Hepatitis B:prevention of liver disease Sydney
                                                                                                                                                     University ethnic communities
                                                                                            Hepatitis B:prevention of liver disease in familys from different of in familys from different ethni
262077   Dr Jason Tye-Din                                    Medical                        T Scholarship
                                NHMRC Postgraduate Scholarships Postgraduate Researchcells in coeliac disease T cells in coeliac disease Walter and Eliza Hall Institute
265603   Dr Mark Berzsenyi                                   Medical                        Associations, outcomes & Associations,GB virus C,&Alfred Hospital and Human Immunodefic
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                     genomics Virus
                                                                                                                          genomics of outcomes Hepatitis C of GB virus C, Hepatitis C Viru
268011   Dr Catherine Banwell NHMRC Project Grants           Standard Project Grant                                      Choice or of contraceptive use by women with HCV and
                                                                                                                                                     Australian by women with hepatitis repro
                                                                                            Choice or chance: the social context chance: contraceptive useNational University their C
284420   A/Pr Hans Netter       NHMRC Development Grants Development Grant                                               Multi-component vaccine Monash University
                                                                                                                                                     for as delivery of HIV-1 platform
                                                                                            Development of chimeric hepatitis B virus like particles thea vaccine deliveryantigens for multi
293803   A/Pr Mark Gorrell      NHMRC Project Grants         ANCARD Project Grant                                        Enzymes important in human liver
                                                                                                                                                     Royal Prince Alfred
                                                                                            Roles of enzymes of the dipeptidyl peptidase gene family in human liver Hospital
295611                                                       Medical                        Studies on the               Studies on the negative chronic antigen B
                                                                                                                                                     St Vincent's Health
         Dr Alexander Thompson NHMRC Postgraduate Scholarships Postgraduate Research Scholarship natural history of e antigennatural history of ehepatitis negative chronic hepatitis
296200   Dr Heidi Drummer       NHMRC Project Grants         Standard Project Grant                                      Structure Virus glycoproteins
                                                                                                                                                     Macfarlane Burnet
                                                                                            Structure and function of Hepatitis Cand function of HCV glycoproteins Institute for Medical Re
300081   Dr Michelle Kermode                                 Public                                                      Risk of therapeutic injection-realted blood-borne virus and non-IDU
                                                                                                                                                     University of Melbourne
                                Early Career Fellowships (Australia) Health (Australia) ECF Risk of therapeutic injection-realted blood-borne virus transmission amongst IDUtransmission
300579   Prof Lisa Maher                                     Population Health CDF
                                Career Development Fellowships                                                             Virus Transmission among Injecting Drug Users (IDUs)
                                                                                                                                                     University of New South Wales
                                                                                            Prevention of Blood-bornePrevention of Blood-borne Virus Transmission among Injecting Drug
307818   Ms Katerina Ajami                                  Dora Lush Biomedical Scholarship
                               NHMRC Postgraduate Scholarships                                                         Functions of Dipeptidyl Peptidase (DP)9
                                                                                           Functions of Dipeptidyl Peptidase (DP)9                University of Sydney
323212   A/Pr David Moore      NHMRC Project Grants         Standard Project Grant                                     Ethno-epidemiology of psychostimulant-related harms
                                                                                                                                                   harms in Australia: An integrated
                                                                                           Improving understanding of psychostimulant-relatedCurtin University of Technology ethno-e
331309   Prof Peter Gage       NHMRC Project Grants         Standard Project Grant                                     Hepatitis virus
                                                                                           Studies of hepacivirus morphogenesis. assembly. Macfarlane Burnet Institute for Medical Re
331312   A/Pr Margaret Hellard NHMRC Project Grants         Standard Project Grant                                     Factors influencing hepatitis C virus infection C virus for Medical Re
                                                                                                                                                  Macfarlane Burnet in injecting drug users
                                                                                           Behavioural, virological and immunological factors influencing hepatitis Institute infection in inje
331324   Dr Peter Higgs                                     Public                         Ethic Vietnamese heroin injectors and BBV transmission
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                    Macfarlane Burnet Institute for
                                                                                                                       Ethic Vietnamese heroin injectors and BBV transmission Medical Re
334269                                                      Medical                        Immunopathogenesis of Hep B virus infection of Hep B virus infection
         Dr Christopher DesmondNHMRC Postgraduate Scholarships Postgraduate Research Scholarship                       Immunopathogenesis         Monash University
334275   Dr Nicholas Walsh                                  Public                         Determinants of recruitment, engagement and management University health care in Australia
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                    Monash of IDUs in
                                                                                                                       Determinants of recruitment, engagement and management of IDUs
334603   Prof Simon Mallal     NHMRC Project Grants         Standard Project Grant                                     Adaptation of Hepatitis C Murdoch University
                                                                                                                                                  to Host HLA-Type
                                                                                           Adaptation of Hepatitis C to Host HLA-Restricted Immune Responses in Australian Population
344806   Dr David Iser                                      Medical                        Pathogensis and             Pathogensis disease in history of of HIV/HBV in the setting
                                                                                                                                                  St Vincent's Health
                               NHMRC Postgraduate Scholarships Postgraduate Research Scholarship ntaural history of liver and ntauralthe setting liver disease coinfection of HIV
349353                                                      RD                                                         Defining the hepatocyte response toof Adelaide
                                                                                                                                                  its role in HCV infection: its role in modu
         Dr MICHAEL BEARD Career Development Fellowships Wright (Biomedical) CDF Defining the hepatocyte response to HCV infection: Universitymodulating liver disease and viru
351008   A/Pr Carolyn Day                                   Public                                                     Impact of injecting patterns and drug Hep C treatment outcomes for
                                                                                                                                                  University of Sydney
                               Early Career Fellowships (Australia) Health (Australia) ECF Impact of injecting patterns and drug dependence treatment on dependence treatment on Hep
351579   A/Pr Elizabeth Powell NHMRC Project Grants         Standard Project Grant                                     How fatty liver injury fibrosis
                                                                                                                                                   fibrogenesis in human liver
                                                                                           The role of steatosis in promoting cellularcausesand University of Queensland disease
351642   Miss Meagan Walsh                                  Dora Lush Biomedical Scholarship
                               NHMRC Postgraduate Scholarships                                                         Investigation of steatosis University of Queensland
                                                                                                                                                  contributes to hepatic fibrogenesis
                                                                                           Investigation of the mechanisms by which the mechanisms by which steatosis contributes to h
358398   Prof Geoffrey Farrell Programs                     Program Grant                                              PROCESSES THAT CAUSE LIVERof Sydney
                                                                                                                                                  University LIVER AND CIRRHOSIS OF
                                                                                           MOLECULAR AND CELLULAR PATHOGENESIS OF HUMANINJURYDISEASE
358772   Dr Mark Douglas                                    CJ Martin (Biomedical) ECF The influence of Hepatitis The influence of HepatitisUniversityMetabolism. Hepatic Lipid Metab
                               Early Career Fellowships (Overseas)                                                                                 C Virus Genotype on
                                                                                                                       C Virus Genotype on Hepatic Lipid of Sydney
376043   Dr Kerry-Lee Milner                                Medical                        Physiological basis of insulin resistance basis of insulin resistance in of Medical Research
                               NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                  Garvan Institute chronic
                                                                                                                       Physiological in chronic hepatitis C virus infection hepatitis C virus
381713   Dr Heidi Drummer      NHMRC Project Grants         Standard Project Grant                                     Neutralizing antibody responses in HCV infected individuals.
                                                                                                                                                  in HCV infected individuals.
                                                                                           Characterization of neutralizing antibody responses Macfarlane Burnet Institute for Medical Re
381732                                                      Industry CDF
         A/Pr Rosemary Ffrench Career Development Fellowships                                                          Development and            of a novel vaccine Institute
                                                                                           Development and immunogenicity testing of testing Macfarlane Burnet strategy for Medical Re
382911   Dr Benjamin Cowie                                  Public                         The seroprevalence, molecularseroprevalence, molecular characterisation & mathematical mo
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                    Melbourne Health
                                                                                                                       The characterisation & mathematical modelling of hepatitis B virus
384702   Prof Simon Mallal     Programs                     Program Grant                                              Interactions between adaptable human host
                                                                                                                                                  Murdoch University
                                                                                           Interactions between adaptable pathogens, drugs and the pathogens, drugs and the human h
390708   Dr Karla Helbig                                    Peter                          Host                        Host Factors Hepatitis C Institute of of Hepatitis C Virus Infection
                                                                                                                                                  Virus Infection
                               Early Career Fellowships (Australia)Doherty (Biomedical) ECF Factors Modulating the Severity of Modulating the SeverityMedical and Veterinary Scienc
396700   Dr Nicholas Wood      NHMRC Project Grants         New Investigator Grant                                      in Indigenous and "at risk" children who received at Westmead
                                                                                                                                                  The Children's Hospital hepatitis
                                                                                           Hepatitis B virus immunity Hepatitis B immunity in Indigenous and "at risk" children B vaccin
399284   Dr MICHAEL BEARD NHMRC Project Grants              Standard Project Grant                                     The role of in modulation University of Adelaide
                                                                                                                                                   of hepatocyte homeostasis HCV replicatio
                                                                                           The role of Cyp2e1, alcohol and HCV alcohol, Cyp2e1 and hepatitis C virus in liver cell biology
399285   Dr MICHAEL BEARD NHMRC Project Grants              Standard Project Grant                                     Hepatitis C virus, chemokines and theirviral hepatitis
                                                                                                                                                  University of role in viral hepatitis
                                                                                           The role of CXCR3 chemokines in hepatitis C and other forms of Adelaide
400920   Prof Andrew Lloyd     NHMRC Project Grants         Standard Project Grant                                     Position and T cells of TUniversity HCV infected liver
                                                                                                                                                   cells in HCV infected liver
                                                                                           Fine positioning and effector function offunction recruited to theof New South Wales
401146   Ms Heidi Coupland                                  Public                         Prevention                  Prevention and managemnetIndo-Chinese infection in Indo-Chines
                                                                                                                                                    in of hepatitis C South Wales
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship and managemnet of hepatitis C infectionUniversity of Newinjecting drug users
401522                                                      Practitioner Fellowship
         Prof Elizabeth Powell Established Career Fellowships                              Practitioner Fellowship     Practitioner Fellowship University of Queensland
401526   Prof ROBERT TINDLE NHMRC Project Grants            Standard Project Grant                                     HBsAg as a generic a generic vector Queensland
                                                                                                                                                  University
                                                                                           Development of Hepatitis B surface antigen as vaccine vector offor the delivery of foreign CTL
402577   Prof Jacob George     NHMRC Project Grants         Standard Project Grant                                     Host factors affecting hepatatis
                                                                                                                                                  University of Sydney
                                                                                           Host determinants of Hepatitis C-associated liver disease C disease
433900   A/Pr David Anderson                                NHMRC Research FellowshipUncoupled Research Fellowship
                               Established Career Fellowships                                                                                     Macfarlane Burnet Institute for Medical Re
                                                                                                                       Uncoupled Research Fellowship
433908   Prof Eric Gowans      NHMRC Project Grants         Standard Project Grant                                     Supressor T cells in hepatitis C virus infection
                                                                                                                                                  Macfarlane Burnet Institute for Medical Re
                                                                                           UNDERSTANDING HEPATITIS C VIRUS-SPECIFIC T CELL TOLERANCE
433913   Dr Heidi Drummer      NHMRC Project Grants         Standard Project Grant                                     Structure and Virus glycoproteins E1 and E2. glycoproteins E1 and
                                                                                                                                                  Macfarlane C Virus
                                                                                           Structure and function of the Hepatitis C function of the HepatitisBurnet Institute for Medical Re
433914   Dr Elizabeth Grgacic  NHMRC Project Grants         Standard Project Grant                                     Identification of HBV fusion
                                                                                                                                                  Macfarlane
                                                                                           A new insight into hepatitis B infection:the HBV fusion peptide Burnet Institute for Medical Re
433929   A/Pr Heidi Drummer                                 RD                                                         Structure and Virus and the HepatitisBurnet Institute for Medical Re
                                                                                                                                                  Macfarlane C Virus and Virus glycoprote
                               Career Development Fellowships Wright (Biomedical) CDF Structure and function of the Hepatitis C function of Human ImmunodeficiencyHuman Immunod
433931   Dr Diah Elhassen                                   Peter
                               Early Career Fellowships (Australia)Doherty (Biomedical) ECF                            Structual analysis of E2 glycoprotein, scavenger Medical class B ty
                                                                                                                                                  Queensland Institute E2 glycoprotein, sca
                                                                                           Structual analysis of interactions between HCVinteractions between HCVof receptor Research
433935   Dr Jacqueline Flynn                                Public                         Stimulation                 Stimulation responses in Macfarlane Burnet Institute for Medical Re
                                                                                                                                                  acute T cell responses in acute HCV infec
                               NHMRC Postgraduate Scholarships Health Postgraduate Scholarship and maintenance of T cell and maintenance of HCV infection
433941                                                      Dora Lush Biomedical Scholarship of the variable regions of Hepatitis C Virus envelope glycoprotein E2 in glycoprotein struc
         Ms Kathleen McCaffrey NHMRC Postgraduate Scholarships                             Role                                                   Macfarlane Burnet Institute for Medical Re
                                                                                                                       Role of the variable regions of Hepatitis C Virus envelope glycoprote
436729   A/Pr Hans Netter      NHMRC Project Grants         Standard Project Grant                                     Design of vaccination tools directedof hepatitis C and pathogens of
                                                                                                                                                  Monash against
                                                                                           Novel generic vaccine approaches applied for the preventionUniversityinfectiousinfluenza virus
448325   Dr Kim Wilson         NHMRC Project Grants          Standard Project Grant                                     Characterisation of Response Response to Hepatitis C Research
                                                                                                                                                    St Vincent's to identify Diagnostic and
                                                                                           Detailed Investigation of the Humoral Immunethe Immuneto HCVInstitute of Medical Virus Pro
453505   A/Pr Allison Jilbert  NHMRC Project Grants          Standard Project Grant                                     Resolution of acute         University infections
                                                                                           Resolution of acute hepatitis B virus infectionshepatitis B virus of Adelaide
453506   A/Pr Allison Jilbert  NHMRC Project Grants          Standard Project Grant                                     Immune therapies for chronicUniversity of B virus infection
                                                                                           Immune therapies for chronic hepatitis B virus infection hepatitis Adelaide
453507   A/Pr Allison Jilbert  NHMRC Project Grants          Standard Project Grant                                     Clonal proliferation of hepatocytes in chronic hepatitis B virus virus
                                                                                                                                                    University of Adelaide
                                                                                           Clonal proliferation of hepatocytes and progression of liver disease in chronic hepatitis Binfecti
454640   A/Pr David Jackson    NHMRC Project Grants          Standard Project Grant                                     A New Method Responses to Design Melbourne
                                                                                                                                                    University
                                                                                           Using the Information inherent in Immune for Vaccine Design ofVaccines
455355   Prof Gregory Dore     Established Career FellowshipsPractitioner Fellowship       Practitioner Fellowship      Practitioner Fellowship University of New South Wales
455985   A/Pr Julie Jonsson    NHMRC Project Grants          Standard Project Grant                                     A new model for fibrosis in and the ductular reaction in hepatic fibro
                                                                                                                                                    University of Queensland
                                                                                           Hepatocyte replicative arrest, hepatic progenitor cells chronic liver disease
457043   Dr Patrick Bertolino  NHMRC Project Grants          Standard Project Grant                                       clearance by the liver: a University of Sydney
                                                                                                                                                    the liver
                                                                                           Understanding rapid T-cellRapid T cell clearance bycritical step towards improved liver transpl
468100   Prof Sharon Lewin     Established Career FellowshipsPractitioner Fellowship       Practitioner Fellowship      Practitioner Fellowship Monash University
491017   Dr Ashley Mansell     NHMRC Project Grants          Standard Project Grant                                     Immunomodulation of Inflammatory Signaling e Antigen
                                                                                                                                                    Monash Hepatitis
                                                                                           Suppression of Immune Toll-like receptor (TLR) signaling by UniversityB Pathways (HBeAg)
496602   Prof Grant Ramm       NHMRC Project Grants          Standard Project Grant                                     in Hepatic Stellate Cell Recruitment and with Liver Disease due to
                                                                                                                                                    Queensland Institute of Medical Research
                                                                                           Role of Chemoattractants Understanding Liver Scarring in ChildrenFibrogenesis in Paediatric
502028   Dr Catherine Croagh                                 Medical                       The role of Hepatitis B E Antigen status in the the Hepatitis B andMelbourne outcomes of chr
                               NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                    University Antigen in determining outcom
                                                                                                                        The significance of natural history Eof therapeutic
508088   A/Pr Michael Beard    NHMRC Project Grants          Standard Project Grant                                     Host genes that control HCV replication and predict treatment respo
                                                                                                                                                     HCV replication and
                                                                                           Identification of interferon stimulated genes that limitUniversity of Adelaidepredict therapeutic o
508950   Prof David Jackson    Established Career FellowshipsNHMRC Research FellowshipUncoupled Research Fellowship                                 University of Melbourne
                                                                                                                        Uncoupled Research Fellowship
510104   Prof Lisa Maher       NHMRC Project Grants          Standard Project Grant                                     Hepatitis B Acceptability University ofIncentive Trial (HAVIT)
                                                                                                                                                    Completion New South Wales
                                                                                           Randomised Controlled Trial of Hepatitis B Vaccineand Vaccine in Injecting Drug Users
510246   Prof Andrew Lloyd     Established Career FellowshipsPractitioner Fellowship       Practitioner Fellowship      Practitioner Fellowship University of New South Wales
510424   Dr Peter Higgs                                      Public                                                      term injecting drug users University of avoidSouth Wales
                                                                                                                                                    avoid users New hepatitis
                               Early Career Fellowships (Australia) Health (Australia) ECF Staying safe: How do longHow do long term injecting drug hepatitis C infection? C infection?
510428   Dr Fabio Luciani                                    Peter
                               Early Career Fellowships (Australia)Doherty (Biomedical) ECF                             Hepatitis the design of vaccines for Hepatitis C and immunological-
                                                                                                                                                    University sequence- virus by
                                                                                           Modelling the evolution of ImprovingC virus by integrating largeof New South Wales predicting
510448   Prof David Cooper     Programs                      Program Grant                                              Vaccines for AIDS and Hepatitis C.
                                                                                           HIV and HCV Vaccines and Immunopathogenesis. University of New South Wales
511201   Prof Elizabeth Powell NHMRC Project Grants          Standard Project Grant                                       treatment response in chronic hepatitis C: mechanisms hepatitis C
                                                                                                                                                    University of Queensland
                                                                                           Role of obesity in impairedRole of obesity in impaired treatment response in chronicand therap
511219   Dr Ingrid Hickman     NHMRC Project Grants          New Investigator Grant                                     Obesity and liver disease:University of Queensland and the role or
                                                                                                                                                     Contributors to liver injury
                                                                                           Obesity-related inflammation and insulin resistance in chronic liver disease: Exercise and diet
511902   Prof Paul Haber       Established Career FellowshipsPractitioner Fellowship       Practitioner Fellowship      Practitioner Fellowship University of Sydney
512031   Dr Venessa Pattullo                                 Medical                       The effect of exercise on insulin resistance and in patients withprofile in hepatitis C. non obe
                               NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                    University chronic obese versus
                                                                                                                        Lifestyle intervention the adipokine of Sydney
512284   Dr David Bowen        NHMRC Project Grants          New Investigator Grant                                     Immune responses to the University of Sydney
                                                                                                                                                     post-liver virus following
                                                                                           Hepatitis C virus-specific cellular immune responseshepatitis Ctransplantation liver transplanta
513896   Prof George Yeoh      NHMRC Project Grants          Standard Project Grant                                     How do liver stem cells grow and develop into functional
                                                                                                                                                    University of Western liver progenitor cells
                                                                                           Mechanisms underlying growth, lineage commitment and differentiation of Australia liver cells?
513961   Dr Aibin Zhang                                       Career - China Exchange Fellowship
                               International (Exchange) EarlyAustraliaFellowships                                       TNF-á and liver progenitor cells
                                                                                                                                                    University of Western Australia
                                                                                           Role of TNF-á in growth, lineage commitment and differentiation of liver progenitor cells
520312                         NHMRC Postgraduate Scholarships Postgraduate Research Scholarship
         Dr Douglas - INACTIVATED Johnson                    Medical                                                    Vaccine responses to self-adjuvanting Melbourne HCV virus viru
                                                                                                                                                     antibody of recombinant
                                                                                           Humoral and neutralising antibody development andUniversity response using Hepatitis Clike p
520671   Dr Scott Patterson                                  Medical                       Clinical studies             New therapies for advanced chronic B.
                                                                                                                                                    University of Melbourne
                               NHMRC Postgraduate Scholarships Postgraduate Research Scholarship of novel antiviral therapies in advanced hepatitishepatitis B virus infection.
521807   Dr Michelle Giles                                   Peter
                               Early Career Fellowships (Australia)Doherty (Biomedical) ECF                             Hepatitis B infection the pregnancy
                                                                                                                                                    Alfred Hospital
                                                                                           Immunological changes during pregnancy and and impact on viral hepatitis infection
543113   A/Pr Heidi Drummer    NHMRC Project Grants          Standard Project Grant                                     How variable regions in HCV E2 modulate glycoprotein function. Re
                                                                                                                                                    Macfarlane Burnet Institute for Medical
                                                                                           Role of the hepatitis C virus glycoprotein E2 variable regions in viral entry and antibody media
543137                         NHMRC Project Grants
         A/Pr Anthony Jaworowski                             Standard Project Grant                                       chronic causes disease Macfarlane Burnet Institute for Medical Re
                                                                                           ITAM signalling proteins inHow HIVviral disease
543143   Prof Eric Gowans      NHMRC Project Grants          Standard Project Grant                                      hepatitis C virus.
                                                                                           Multiple vector vaccine forA novel HCV vaccine           University of Adelaide
543144   Prof Eric Gowans      NHMRC Project Grants          Standard Project Grant                                      treat HCV infection.
                                                                                           A novel immunotherapy toA new HCV cell therapy. University of Adelaide
546249   Dr Jennifer Audsley                                 Australian Clinical Research ECF
                               Early Career Fellowships (Australia)                                                     Long-term implications and B virusUniversity
                                                                                                                                                    Monash (HBV) treatment in HIV-HBV co-
                                                                                           Long-term implications and outcomes of anti hepatitis outcomes of anti hepatitis B virus (HBV)
567057                                                       CJ Martin (Biomedical) ECF A whole genome association studydeterminants of clinical outcome and and treatment respons
         Dr Alexander Thompson Early Career Fellowships (Overseas)                                                                                  of clinical outcome treatment response in
                                                                                                                        Genetic for determinantsUniversity of Melbourne
567174   Miss Sarah Moneer                                   Dora Lush Biomedical Scholarship
                               NHMRC Postgraduate Scholarships                                                          Innate immunity in - a potential role of Melbourne
                                                                                                                                                    University for NK cells and NKR expressio
                                                                                           Immune correlates of protection against HCVHepatitis C virus infection
568859   Dr Mark Danta         NHMRC Project Grants          Standard Project Grant                                     Defining sexual transmisison of for acute among Wales
                                                                                                                                                    University of New South gay men
                                                                                           Defining risk and mechanisms of permucosal transmissionhepatitis CHCV infection within high
568885   Prof John Kaldor                                    Centre of Clinical Research Excellence Clinical Research Excellence in Aboriginal Health: Sexually South Wales
                               Centres for Research Excellence                             Centre for                                               University of New transmitted and Sexua
                                                                                                                        Centre for Clinical Research Excellence in Aboriginal Health:bloodb
 568985   Prof Gregory Dore        NHMRC Partnerships                                           Health                     Assessment and treatment of hepatitis New South Walesusers drug
                                                                                                                                                        University of C injecting drug
                                                                Partnership Projects for BetterEvaluation of a model for assessment and treatment of HCV amongvirus among injectingin op
 594444   Prof Tony Butler         NHMRC Project Grants         Standard Project Grant                                     Hepatitis Opportunities (HePATO) of New South Wales
                                                                                                                                                        University
                                                                                               Hepatitis C, Prisons and Treatment C, Prisons and Treatment Opportunities (HePATO)
 603735   A/Pr Heidi Drummer       NHMRC Project Grants         Standard Project Grant                                     Structure and Function the HCV glycoproteins
                                                                                               Structure and Function of the HCV glycoproteins of Macfarlane Burnet Institute for Medical Re
 603755   Rachel Sacks-Davis                                    Public                         Relationships between phylogeny ofdont lie: predicting sources of HCV Institute for Medical Re
                                   NHMRC Postgraduate Scholarships Health Postgraduate Scholarship                                                      Macfarlane Burnet infections from a coho
                                                                                                                           Genetics hepatitis C viruses and social network structure insocial c
 603756   Ms Rebecca Winter                                     Public                         Examining                   Examining mortality and sevice utilisation among ex-prisoners
                                                                                                                                                        Macfarlane mortality and sevice utilisation
                                   NHMRC Postgraduate Scholarships Health Postgraduate Scholarship drug-related morbidity anddrug-related morbidity andBurnet Institute for Medical Re
 626906   A/Pr Michael Beard                                    NHMRC Research FellowshipUncoupled Research Fellowship
                                   Established Career Fellowships                                                          Uncoupled Research FellowshipUniversity of Adelaide
 628953   Dr Eu Jin Lim                                         Medical                        The Effects of              Viral Proteins Hepatitis CUniversity of Setting of
                                                                                                                                                         and Transplant Medications on The Liver
                                   NHMRC Postgraduate Scholarships Postgraduate Research ScholarshipHepatitis C The Effects of On Liver Fibrosis In The MelbourneImmunosuppressa
 630463   A/Pr David Wilson        NHMRC Project Grants         Standard Project Grant                                     Modelling and cost-effectiveness of hepatitis C biomedical intervent
                                                                                                                                                        University of New South Wales
                                                                                               Modelling and economic evaluation of hepatitis C epidemic mitigation strategies in Australia
 630483   Prof Lisa Maher          NHMRC Project Grants         Standard Project Grant                                     Hepatitis C Vaccine Preparedness Study South Wales
                                                                                                                                                        University of New
                                                                                               Hepatitis C Vaccine Preparedness Study: Investing in Infectious Disease Prevention
 630732   Dr Anna Olsen                                         Australian Training ECF for Aboriginal andA study Strait Islander of hepatitis B knowledge, treatment South Wales
                                   Early Career Fellowships (Australia)                                                    A study Health Research University of New and health care among
                                                                                               Liver spots: Torres of Hepatitis B knowledge, treatment and health care among Indigenous A
 630733   Dr Rowena Bull                                        Peter
                                   Early Career Fellowships (Australia)Doherty (Biomedical) ECF                            Understanding hepatitis CUniversity of
                                                                                                                                                         virus infection
                                                                                               Virus-host interactions contributing to hepatitis C virus chronicity New South Wales
 630754   Bethany White                                         Public                         Hepatitis                   Hepatitis C Vaccine field-based vaccine trials
                                                                                                                                                        University
                                   NHMRC Postgraduate Scholarships Health Postgraduate ScholarshipC vaccine preparedness: feasibility ofpreparedness of New South Wales
 637350   Dr Marc Pellegrini                                    Clinical CDF
                                   Career Development Fellowships                                                          Indentifying new treatments for chronic viral diseases
                                                                                                                                                        pathways to promote Institute
                                                                                               Trageted manipulation of host genes and signalling Walter and Eliza Hall immune clearance o
1001144   Prof Margaret Hellard                                 Centre for Research Excellence in Population Health Research the health, social and economic burden of injecting drug u
                                   Centres for Research Excellence                                                         Reducing                      injecting drug use in Australia
                                                                                               Reducing the health, social and economic burden ofMacfarlane Burnet Institute for Medical Re
1003741   Dr Meredith O'Keeffe                                  RD                                                         The involvement of dendritic cellsmanipulation
                                                                                                                                                        clinical in Burnet Institute for Medical Re
                                   Career Development Fellowships Wright (Biomedical) CDF Dendritic cells in innate immunity and their potential Macfarlanethe first line of defense against
1003767   Prof Jacob George        NHMRC Project Grants         Standard Project Grant                                     Endocannabinoids in chronic hepatitis C
                                                                                               The role of endocannabinoids in chronic hepatitis C University of Sydney
1004242   Prof Elizabeth Powell                                 Practitioner Fellowship
                                   Established Career Fellowships                                                           resistance and fatty liver University of Queensland (steatosis) in hu
                                                                                                                                                        (steatosis) in human liver
                                                                                               The role of obesity, insulinThe role of obesity, insulin resistance and fatty disease and strategie
1004847   A/Pr Allison Jilbert     NHMRC Project Grants         Standard Project Grant                                     Hepatitis Circular DNA University Circular DNA
                                                                                               Hepatitis B Virus Covalently ClosedB Virus Covalently Closed of Adelaide
1006331   Dr Gail Matthews         NHMRC Project Grants         Standard Project Grant                                     Evidence for naturally occurring resistance South Walesin drugs in
                                                                                                                                                         Acting Antiviral Drugs (DAAs)
                                                                                               Evaluation of naturally occurring resistance to DirectUniversity of New to antiviral HCV individua
1006592   Dr Marc Pellegrini       NHMRC Project Grants         New Investigator Grant                                     Understanding the host factors that limit clearance of chronic viruse
                                                                                                                                                         mediated Eliza Hall an analysis and ma
                                                                                               Chronic active viral persistence versus host immuneWalter andpathology: Institute
1006759   A/Pr David Booth         NHMRC Project Grants         Standard Project Grant                                     IL28B hepatitis C virus University of Sydney
                                                                                               The effect of IL28B haplotype onand hepatitis C infection and treatment response
1011024   Prof Stephen Locarnini   NHMRC Project Grants         Standard Project Grant                                     Can Hepatitis B therapy enhance theHealth
                                                                                                                                                        Melbourne progression to Liver Cancer?
                                                                                               ANTIVIRAL DRUG RESISTANT HBV: PATHOGENIC AND ONCOGENIC SIGNIFICANCE OF
1011319   Prof Ian James           NHMRC Project Grants         Standard Project Grant                                     Statistical issues geneticMurdoch University
                                                                                                                                                         associations
                                                                                               Statistical issues in the analysis of host-viralin host-viral association studies
1016351   Prof Andrew Lloyd        NHMRC Partnerships                                           Health                     Prevention and amongst University
                                                                                                                                                        of viral hepatitis amongst prisoners
                                                                Partnership Projects for BetterPrevention and treatment of viral hepatitis treatmentprisoners of New South Wales
1017139   Dr Paul Clark                                         Medical                        Individualising             Individualising care of patients with chronic hepatitis and
                                                                                                                                                        University of New South Wales
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship care for patients with chronic hepatitis C: predicting side effects C treatment r
1017465   Mr Jesse Toe             NHMRC Postgraduate Scholarships                                                           diseases – enhancing host immune effector function
                                                                                               Clearing chronic infectiousClearing chronic infectious diseases – enhancing host immune effec
                                                                Dora Lush Biomedical Scholarship                                                        Walter and Eliza Hall Institute
1017784   Dr Uma Devi                                           Public                         Hepatitis                   HBV drug resistance and University of Melbourne
                                                                                                                                                        vaccine escape
                                   NHMRC Postgraduate Scholarships Health Postgraduate ScholarshipB Virus Drug Resistance: Impact on the Immunisation Program
1018023   Dr Joseph Doyle                                       Medical                        Early Treatment             Early Treatment of Hepatitis C Virus in Australia
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship of Hepatitis C Virus in Australia                  Macfarlane Burnet Institute for Medical Re
1018079   Dr Kate O'Connor                                      Medical                        Functional pharmacogenetics: Analysis offunctional University of IL28B genotype on response
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                                    effect of the the IL28B
                                                                                                                           Analysis of the the functional effect of Sydney genotype on hepa
1020175   A/Pr Heidi Drummer       NHMRC Project Grants         Standard Project Grant                                     Variable regions of HCV glycoprotein E2
                                                                                                                                                        Macfarlane virus Institute for Medical Re
                                                                                               Roles of the hepatitis C virus glycoprotein E2 variable regions inBurnetentry, immunogenicity a
1022144   Dr Michael Gantier       NHMRC Project Grants         New Investigator Grant                                     microRNA regulation of antiviral responses
                                                                                               microRNA regulation of antiviral responses               Monash University
1023437   Prof Carla Treloar       NHMRC Project Grants         Standard Project Grant                                     Hepatitis C transmission and within sexual partnerships
                                                                                                                                                        University of New South Wales
                                                                                               Understanding and preventing hepatitis C transmission intimate injectors
1024406   Prof Sharon Lewin        NHMRC Project Grants         Standard Project Grant                                     HIV-HBV co-infection
                                                                                               Liver disease in HIV-HBV co-infection                    Monash University
1027641   A/Pr Michael Beard       NHMRC Project Grants         Standard Project Grant                                     Imaging the hepatitis C University of Adelaide
                                                                                               Imaging the hepatitis C virus life cycle in real-time virus life cycle in living cells
1028432   Prof Gregory Dore                                     Practitioner Fellowship
                                   Established Career Fellowships                              Practitioner Fellowship     Practitioner Fellowship University of New South Wales
1032096   Dr Amany Zekry           NHMRC Project Grants         New Investigator Grant                                      liver inflammation and chronic hepatitis C South Wales
                                                                                                                                                        University of New
                                                                                               Inflammatory mediators of Liver injury in chronic hepatitis C
1034029   A/Pr Michael Kotiw       NHMRC Project Grants         Standard Project Grant                                     Development of of Hepatitis B virus like particles the dual prevention
                                                                                                                                                        University of Southern expressing
                                                                                               Construction and immunogenic evaluation a novel recombinant vaccine forQueenslandT and B
1035383   Dr Jason Grebely                                      Population Health CDF
                                   Career Development Fellowships                                                          Epidemiology, natural history and treatment of in injecting
                                                                                                                                                        University infection HCV in injecting drug
                                                                                               Epidemiology, natural history and treatment of hepatitis C virusof New South Wales drug users
1038356   Dr Jane Davies                                  Medical                   Hepatitis B in the           of the Northern Territory: Menzies School Hepatitisdisease and hea
                                                                                                                                            epidemiology, burden of Research
                                 NHMRC Postgraduate Scholarships Postgraduate Research Scholarship Top EndThe Epidemiology and Disease Burden of of Health B Infection in th
1039019   Dr Roslyn Vongsuvanh                            Medical                   Studies on the               Studies on the pathogenesis and early diagnosis
                                                                                                                                            hepatocellular carcinoma
                                 NHMRC Postgraduate Scholarships Postgraduate Research Scholarship pathogenesis and early diagnosis of University of Sydney of hepatocellular c
1039055   Dr Kasha Singh                                  Medical                   The role of stellate cells inDissecting mechanisms ofprogression inprogression in B co-infectio
                                 NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                           liver disease HIV-Hepatitis HIV-Hepatitis
                                                                                                                 fibrosis and liver disease Monash University
1039597   Prof Paul Hertzog      NHMRC Development Grants Development Grant                                      Development of new antivirals.
                                                                                    Development of new antivirals.                          Monash University
        App    Start
State                  1994-95   1995-96   1996-97   1997-98   1998-99   1999-00    2000-01    2001-02    2002-03   2003-04   2004-05   2005-06
        Year   Year
VIC     1994    1995   $19,142   $69,308   $95,500 $106,573    $78,380    $17,141    $38,489    $38,489
NSW     1995    1996             $24,786   $44,111 $30,546     $33,038    $49,671    $27,855
WA      1995    1996              $8,432    $9,864   $8,569    $15,954    $13,259     $4,442
NSW   1996   1997   $17,344   $50,761 $71,352      $70,815    $49,967    $17,088
SA    1997   1998             $71,065 $152,441    $152,114    $70,738
QLD   1997   1998             $52,777 $111,715    $108,631    $49,693
VIC   1997   1998             $25,988 $55,607      $55,651    $26,032
NSW   1997   1999                       $7,730     $22,604    $29,770    $14,896
VIC   1997   1999                      $20,047     $35,000    $14,953
VIC   1997   1999                      $27,478     $47,500    $20,022
NSW   1997   1999                       $9,204     $30,000    $20,796
VIC   1997   1999                      $20,505     $30,000     $9,495
QLD   1997   1999                      $13,146     $28,018    $24,354     $9,482
VIC   1997   1999                      $20,667     $49,268    $46,833    $18,232
NSW   1997   1999                      $12,314     $22,500    $10,186
NSW   1997   1999                      $16,091     $49,267    $66,409    $33,234
WA    1997   1999                      $12,883     $21,000     $8,117
VIC   1997   1999                      $15,090     $65,000    $49,910
VIC   1997   2000                                  $18,750    $32,500    $13,750
NSW   1997   1998             $12,252   $49,992    $57,579    $48,999    $29,160
NSW   1998   1999                       $65,639   $122,313   $122,118    $67,084    $1,640
VIC   1998   1999                       $47,782    $89,640    $89,655    $47,797
NSW   1998   1999                       $77,657   $145,173   $143,798    $76,281
QLD   1998   1999                       $35,214    $66,396    $65,155    $35,468    $1,496
WA    1998   1999                       $12,749    $26,193    $27,072    $20,519    $7,207     $316
VIC   1998   1999                       $12,749    $26,193    $27,072    $13,628     $168      $168
VIC   1998   1999                        $8,818    $18,103    $18,707    $12,320    $5,407    $2,508
VIC   1999   2000                                  $28,148    $42,954    $14,806
VIC   1999   2000                                  $19,086    $58,665    $78,741   $70,913   $31,750
NSW   1999   2000                                   $9,286    $18,707    $19,028   $14,481    $4,874   $222   $222
VIC   1999   2000                                  $13,445    $27,072    $27,524   $13,897
SA    1999   2000                                  $13,445    $27,072    $13,628
NSW   1999   2000                                  $13,445    $27,072    $13,628    $7,452    $7,452
VIC   1999   2000                                  $32,709    $66,150    $66,798   $33,357
QLD   1999   2001                                             $99,761   $167,440   $67,679
SA    1999   2000                                  $25,639    $52,933    $27,294
VIC   1999   2000                                  $86,091   $206,894   $185,843   $65,041
VIC   1999   2000                                  $31,250    $64,177    $67,692   $34,765
NSW   1999   2000                                  $24,708    $51,002    $55,123   $28,829
VIC   2000   2001                                             $53,893   $107,953   $54,061
NSW   2000   2001                                             $45,238    $90,755   $91,035   $45,518
NSW   2000   2001   $32,643    $65,453    $65,621    $32,811
NSW   2000   2001   $35,190    $70,604    $70,828    $35,414
NSW   2000   2001   $13,628    $27,524    $28,113    $14,470      $254
VIC   2000   2001   $35,143    $70,453    $70,621    $70,621    $73,621    $38,311
VIC   2000   2001   $33,183    $80,683    $97,125   $107,750   $117,375   $119,500
VIC   2000   2001   $60,238   $120,755   $121,035    $60,518
NSW   2000   2001   $47,643    $98,057    $50,414
SA    2000   2001   $62,690   $125,604   $125,828    $62,914
SA    2000   2001   $37,690    $75,604    $75,828    $37,914
VIC   2000   2001   $60,143   $120,453   $120,621    $60,311
NSW   2000   2001   $13,628    $27,524    $20,946     $7,050
VIC   2001   2002              $75,385   $150,770   $150,770    $75,385
VIC   2001   2002              $65,000   $132,500   $120,938    $53,438
VIC   2001   2002              $32,665    $67,885    $35,220
SA    2001   2002              $62,720   $125,440   $125,440    $62,720
VIC   2001   2002               $9,607    $19,437    $17,855     $8,025
QLD   2001   2002              $41,165    $82,330    $82,330    $41,165
VIC   2001   2002              $67,775   $135,550   $135,550    $67,775
QLD   2001   2002              $12,164    $24,609    $17,750     $5,306
NSW   2001   2003                        $200,000   $400,000   $400,000   $400,000
NSW   2002   2003                         $93,500   $187,000   $187,000   $187,000
NSW   2002   2003                          $4,955    $15,197    $22,713    $19,808
VIC   2002   2003                         $63,000   $125,813   $128,125    $84,063
VIC   2002   2003                          $7,352    $17,594    $20,661    $18,387
VIC   2002   2003                          $9,830    $20,072    $20,661    $10,419
NSW   2002   2003                         $53,875   $107,750    $53,875
WA    2002   2003                         $41,750    $83,500    $83,500    $41,750
NSW   2002   2003                         $38,520    $82,136    $54,329    $48,089
NSW   2002   2003                          $9,830    $20,072    $21,490    $12,334
VIC   2002   2003                         $14,216    $28,961    $29,752    $22,678
VIC   2003   2004                                    $14,745    $29,752    $30,307
ACT   2003   2004                                    $72,263   $130,075    $57,813
VIC   2003   2004                                    $17,438    $69,750    $52,313
NSW   2003   2005                                               $39,875    $39,875
VIC   2003   2004                                    $14,745    $29,752    $30,307
VIC   2003   2004                                    $80,125   $160,250   $160,250
VIC   2003   2004                                    $32,375    $65,375    $66,625
NSW   2003   2004                                    $42,625    $86,250    $88,125
NSW   2003   2004   $10,242    $20,661    $21,034
WA    2004   2005             $107,905   $220,810
VIC   2004   2005              $80,125   $160,250
VIC   2004   2005             $161,688   $341,375
VIC   2004   2005              $13,155    $26,563
VIC   2004   2006                   $1    $15,301
VIC   2004   2005              $27,663    $42,963
WA    2004   2005              $80,125   $160,250
VIC   2004   2005              $15,007    $30,307
SA    2004   2005              $43,625    $88,125
NSW   2004   2005              $33,000    $52,167
QLD   2004   2005              $69,063   $138,125
QLD   2004   2005              $10,419    $21,035
NSW   2004   2005             $473,693   $956,387
NSW   2004   2005              $23,057    $69,827
NSW   2005   2006                          $8,150
VIC   2005   2006                         $77,125
VIC   2005   2006
VIC   2005   2006                         $15,300
WA    2005   2006                        $586,944
SA    2005   2006                         $33,625
NSW   2005   2006                         $82,050
SA    2005   2006                         $74,250
SA    2005   2006                         $74,625
NSW   2005   2006                         $54,188
NSW   2005   2006                         $10,616
QLD   2005   2006                         $28,313
QLD   2005   2006                         $71,750
NSW   2005   2006                        $105,850
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2008
QLD   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
SA    2006   2007
SA    2006   2007
SA    2006   2007
VIC   2006   2007
NSW   2006   2007
QLD   2006   2007
NSW   2006   2007
VIC   2007   2008
VIC   2007   2008
QLD   2007   2008
VIC   2007   2008
SA    2007   2008
VIC   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2008   2009
QLD   2007   2008
QLD   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2007   2008
WA    2007   2008
WA    2007   2008
VIC   2007   2008
VIC   2007   2008
VIC   2008   2009
VIC   2008   2009
VIC   2008   2009
SA    2008   2009
SA    2008   2009
VIC   2008   2009
VIC   2008   2009
VIC   2008   2009
NSW   2008   2009
NSW   2008   2009
NSW   2008   2010
NSW   2009   2010
VIC   2009   2010
VIC   2009   2010
VIC   2009   2010
SA    2009   2010
VIC   2009   2010
NSW   2009   2010
NSW   2009   2010
NSW   2009   2010
NSW   2009   2010
NSW   2009   2010
VIC   2009   2010
VIC   2009   2010
VIC   2010   2011
NSW   2010   2011
QLD   2010   2011
SA    2010   2011
NSW   2010   2011
VIC   2010   2011
NSW   2010   2011
VIC   2010   2011
WA    2010   2011
NSW   2010   2011
NSW   2010   2011
VIC   2010   2011
VIC   2010   2011
VIC   2010   2011
NSW   2010   2011
VIC   2011   2012
VIC   2011   2012
NSW   2011   2012
VIC   2011   2012
SA    2011   2012
NSW   2011   2012
NSW   2011   2012
QLD   2011   2012
NSW   2011   2012
NT    2011   2012
NSW   2011   2012
VIC   2011   2012
VIC   2011   2012

                    Expenditure $2,416,546 $2,632,876 $2,619,757 $2,640,865 $3,297,658 $5,095,481
                    # of grants     52         48         46         44         45         49
2006-07   2007-08   2008-09   2009-10   2010-11   2011-12   2012-13   2013-14   2014-15   2015-16   2016-17   Total

                                                                                                              $463,022
                                                                                                              $210,005
                                                                                                               $60,520
$277,327
$446,359
$322,816
$163,278
 $75,000
 $70,000
 $95,000
 $60,000
 $60,000
 $75,000
$135,000
 $45,000
$165,000
 $42,000
$130,000
 $65,000
$197,982
$378,794
$274,875
$442,908
$203,728
 $94,055
 $79,978
 $65,862
 $85,909
$259,155
 $66,819
 $81,937
 $54,144
 $69,048
$199,014
$334,881
$105,866
$543,868
$197,885
$159,663
$215,906
$272,546
                                 $196,528
                                 $212,037
                                   $83,988
                                 $358,770
 $60,250                         $615,866
                                 $362,546
                                 $196,113
                                 $377,037
                                 $227,037
                                 $361,528
                                   $69,147
                                 $452,310
                                 $371,875
                                 $135,770
                                 $376,320
                                   $54,923
                                 $246,990
                                 $406,650
                                   $59,829
$400,000   $200,000             $2,000,000
$193,625   $100,125              $948,250
  $7,473      $135                 $70,281
 $18,750                         $419,750
  $7,969      $289      $289       $72,541
   $313       $313                 $61,607
                                 $215,500
                                 $250,500
 $56,375    $19,000              $298,449
  $1,453      $368                 $65,546
  $7,671                         $103,277
 $23,134     $7,834              $105,771
                                 $260,150
                                 $139,500
                                   $79,750
 $23,177     $7,877              $105,857
 $80,125                         $480,750
 $67,875    $34,250              $266,500
 $89,750    $91,500   $46,250    $444,500
   $16,097     $5,702        $378         $157                                       $74,271
 $198,310     $85,405                                                              $612,430
 $160,250     $80,125                                                              $480,750
 $320,031 $140,344                                                                 $963,438
   $27,190    $13,782                                                                $80,689
   $31,011    $31,713     $24,181       $8,179                                     $110,385
   $23,177     $7,877                                                              $101,680
 $160,250     $80,125                                                              $480,750
   $31,011    $23,732      $8,021                                                  $108,078
   $89,750    $91,500     $93,375      $47,125                                     $453,500
   $53,417    $69,125     $57,531      $48,344     $25,688                         $339,271
 $138,125     $69,063                                                              $414,375
   $16,097     $5,820        $338                                                    $53,708
 $965,387 $995,034      $1,025,081    $512,741                                    $4,928,324
   $69,507    $61,361      $78,000     $39,375                                     $341,127
   $16,027    $23,318      $27,115     $11,675                                       $86,285
 $155,939 $161,913         $83,099                                                 $478,077
   $46,125 $119,646      $121,646      $90,989     $42,864                         $421,270
   $31,011    $23,732       $8,021                                                   $78,064
$1,185,627 $1,197,366   $1,158,989   $1,079,354   $519,047                        $5,727,327
   $67,875    $69,125      $70,500      $35,625                                    $276,750
 $106,881     $24,831                                                              $213,763
 $150,189 $153,510        $77,571                                                  $455,521
 $150,841 $154,009        $77,793                                                  $457,268
 $104,419 $106,799        $56,568                                                  $321,974
   $21,549    $22,062     $11,129                                                    $65,354
   $56,063    $58,313     $61,188      $61,821     $31,196                         $296,892
 $145,028 $148,071        $74,793                                                  $439,643
 $214,130 $199,338        $91,058                                                  $610,376
   $59,500 $120,250      $122,625     $124,926    $127,236   $129,462   $65,277    $749,275
   $70,113 $141,734      $144,743      $73,121                                     $429,710
   $87,100 $176,075      $179,814      $90,839                                     $533,828
   $47,050    $95,046     $97,055      $49,059                                     $288,210
              $45,250     $90,500      $92,375     $96,009    $98,600   $49,715    $472,450
   $34,250    $77,844     $79,219      $71,879     $36,254                         $299,446
   $10,933    $22,062     $22,467      $17,543      $6,204                           $79,209
   $10,933    $22,062     $22,467      $17,543      $6,204                           $79,209
   $64,038 $129,387      $132,127      $66,777                                     $392,328
$63,250   $127,768    $130,483       $65,966                                                         $387,467
$61,163   $120,971    $120,930       $61,121                                                         $364,185
$58,613   $118,421    $120,930       $61,121                                                         $359,085
$68,313   $138,536    $141,967       $71,744                                                         $420,558
$72,338   $166,791    $190,948       $96,495                                                         $526,572
           $81,638    $123,725       $84,974     $86,546      $43,659                                $420,542
$86,125   $174,036    $177,717       $89,806                                                         $527,683
$67,275   $135,916    $138,792       $70,151                                                         $412,134
           $35,313      $71,375      $72,810      $74,156     $75,454      $38,045                   $367,153
           $88,493    $178,967     $182,668       $92,193                                            $542,321
           $96,150    $194,436     $198,438     $100,152                                             $589,175
           $16,002      $32,316      $28,170      $11,856                                              $88,343
           $63,555    $128,467     $131,057       $66,145                                            $389,225
           $75,125    $151,750     $154,706     $157,566     $150,960      $71,475                   $761,582
           $97,430    $189,157     $134,248       $42,521                                            $463,355
           $49,438      $99,925    $101,934     $103,819     $105,635       $53,263                  $514,014
            $8,719      $44,344      $71,879      $73,161      $65,057      $28,150                  $291,310
           $17,438      $53,063      $71,879      $73,161      $55,674      $18,767                  $289,980
                     $1,808,890   $3,652,149   $3,718,439   $3,781,051   $3,811,741   $1,905,871   $18,678,141
           $88,170    $178,248     $181,868       $91,789                                            $540,075
           $57,900    $164,393     $212,355     $105,862                                             $540,510
           $29,438      $59,500      $60,696      $61,818     $62,900      $31,715                   $306,067
           $16,002      $32,316      $34,189      $17,875                                            $100,381
           $90,518    $162,137     $144,599       $72,980                                            $470,233
           $87,400    $176,686     $180,267       $90,981                                            $535,333
           $53,775    $114,295       $60,520                                                         $228,589
           $16,002      $32,316      $34,189     $27,083       $9,208                                $118,796
           $16,002      $32,316      $16,314                                                           $64,631
                        $43,125      $86,879     $88,296      $89,840      $45,299                   $353,439
                        $88,750    $179,186     $182,481      $92,046                                $542,462
                        $74,588    $150,592     $153,362      $77,358                                $455,899
                        $77,138    $165,876     $171,383      $82,645                                $497,041
                        $84,124    $179,499     $199,920     $104,545                                $568,088
                        $26,719      $62,973     $73,161      $74,441      $46,917       $9,383      $293,594
                        $50,343      $97,926     $88,307      $82,140      $41,416                   $360,133
                        $11,339      $23,714     $25,039      $12,664                                  $72,754
                        $68,088    $132,271     $129,504      $65,320                                $395,182
                      $250,000     $500,000     $504,500     $513,327     $517,653     $258,827     $2,544,306
$149,594   $301,785   $306,969   $309,556   $154,778                                 $1,222,683
 $98,556   $125,590    $27,034                                                        $251,179
 $98,078   $197,911   $201,354   $101,521                                             $598,864
 $12,375    $24,930    $25,794    $13,239                                               $76,339
 $12,375    $24,930    $25,794    $13,239                                               $76,339
 $57,064   $115,155   $117,170   $118,157   $118,157    $59,079                       $584,783
 $17,875    $36,018    $37,183    $19,040                                             $110,115
 $76,170   $153,709   $156,397    $78,857                                             $465,133
$137,857   $275,591   $272,527   $134,793                                             $820,767
 $36,254    $73,161    $74,441    $75,068    $37,534                                  $296,457
 $36,254    $73,161    $55,026    $46,270    $65,684    $37,534                       $313,930
  $9,324    $21,879    $19,317     $6,762                                               $57,282
 $48,020    $96,904    $98,600    $99,431    $49,715                                  $392,670
 $59,839   $307,702   $544,851   $549,064   $489,529   $423,307   $185,854           $2,560,145
            $54,071   $109,061   $109,981   $109,981    $54,990                       $438,084
            $92,195   $180,781   $187,525    $98,939                                  $559,440
            $31,185    $62,900    $63,430    $63,430    $63,430    $31,715            $316,090
            $49,632   $100,107   $100,951    $50,475                                  $301,164
            $83,608   $166,889    $83,282                                             $333,779
            $68,581   $138,327   $139,493    $69,746                                  $416,147
            $93,818   $181,467   $167,532    $79,884                                  $522,701
            $83,426   $168,270   $169,689    $84,844                                  $506,230
            $43,131    $84,406    $82,551    $41,276                                  $251,364
           $178,139   $363,033   $369,789   $184,894                                 $1,095,855
            $18,143    $27,788     $9,645                                               $55,576
            $12,555    $25,544    $26,229    $13,239                                    $77,567
            $18,143    $36,933    $37,829    $19,040                                  $111,945
            $18,143    $36,933    $37,829    $19,040                                  $111,945
            $18,143    $37,183    $19,040                                               $74,365
                      $111,817   $223,633   $223,633   $111,817                       $670,900
                       $79,438   $163,961   $166,503    $81,980                       $491,882
                       $65,445   $128,348   $122,946    $60,043                       $376,782
                       $60,712   $169,056   $204,292   $177,909    $81,960            $693,930
                       $78,195   $156,389   $156,389    $78,195                       $469,168
                       $53,263   $106,526   $106,526   $106,526   $106,526 $53,263    $532,628
                       $57,206   $114,413   $114,413    $57,206                       $343,238
                       $81,983   $163,966   $163,966    $81,983                       $491,897
                       $49,716    $99,431    $99,431    $99,431    $49,716            $397,724
                                                            $18,809     $37,618      $37,868      $19,059                         $113,353
                                                                        $18,809      $37,868      $19,059                          $75,735
                                                            $14,107     $32,915      $37,868      $23,761      $4,702             $113,353
                                                           $105,605    $211,209     $105,605                                      $422,418

$6,650,248 $7,581,089 $9,968,534 $11,294,311 $10,266,097 $10,230,361 $9,615,499   $5,501,574   $1,555,309   $460,473    $53,263 $95,266,182
    59         76         70          72          67          62         54           34           17          6           1
Broad Research Field Of   Research Research Research Research Research Health   Health   Health   Health   Health
                                                                                                                      Status
Area           Research   KW 1     KW 2     KW 3     KW 4     KW 5     KW 1     KW 2     KW 3     KW 4     KW 5
Basic Science      Medical Virology                                                                                 Closed
                   Epidemiology          B             TRACING A
Clinical Medicine and Science HEPATITISVARIANTSCONTACT VIRULENCENALYSTS                                             Closed
Basic Science                  HEPATITISGENOTYPES
                   Medical Virology      C             CELLULARVIRAL
                                                                IMMUNITY
                                               RECOMBINANT PEPTIDES PERSISTENCE                                     Closed
                   Immunology not elsewhere classified
                                              C          INFLAMMATION
Clinical Medicine and Science HEPATITISIMMUNOPATHOGENESIS CLEARANCE   VIRAL       CHEMOKINES                                                               Closed
Basic Science                   HEPADNAVIRUSES HEPATOCYTES
                   Medical Virology         RESOLUTION OF INFECT                  CYTOKINES
                                                                      AGE-RELATED EFFECTS                                                                  Closed
Basic Science                   HEPATITISMOLECULAR EVENTS
                   Medical Virology           C VIRUS REPLICATION     CONTROL MECHANISMS                                                                   Closed
Basic Science                   HEPATITISMINICHROMOSOME NUCLEOSOMES
                   Medical Virology           B VIRUS CHROMATIN                   TRANSCRIPTION                                                            Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Counselling                                                                                                                      Closed
Basic Science      Medical Virology                                                                                                                        Closed
Public Health      Medical Virology                                                                                                                        Closed
Basic Science      Medical Virology                                                                                                                        Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Public Health      Health Promotion                                                                                                                        Closed
Basic Science                   RNA          and biophysics
                   Biomedical engineering VIRUS          RIBOZYMESTRUCTURE        ANTIGEN                                                                  Closed
Public Health      Medical Virology                                                                                                                        Closed
Basic Science                   HEPATITISPOLYMERASE ENVELOPE PROTE
                   Medical Virology           B VIRUS VIRAL                         B VACCINE
                                                                      HEPATITISANTIVIRALS                                                                  Closed
Public Health      Health Information Systems (incl. Surveillance)                                                                                         Closed
Basic Science                   HEPATITISVIRUS INFECTION IMMUNE PERTURBATION
                   Medical Virology           C VIRUS IMMUNOTHERAPY DENDRITIC CELLS                                                                        Closed
                   Medical Virology           C          NATURAL CYTOTOXIX T MICE
Clinical Medicine and Science HAPATITISINTERFERON-ALPHAKILLER CELLSCELL           SCID                                                                     Closed
                   Immunology not elsewhere classified   LATEX ALLERGENS
Clinical Medicine and Science ALLERGY T-CELL EPITOPES B-CELL EPITOPES                                                                                      Closed
                   Medical Virology           E VIRUS,HE
Clinical Medicine and Science HEPATITISPROTEIN PROCESSING             IMMUNE RESPO  IMMUNE RESP
                                                         HUMORALCELLULARDNA IMMUNIZATION                                                                   Closed
Public Health                   H             C
                   Epidemiology EPATITISETHNIC HEALTH                 HEALTH ACCESS TO
                                                         WOMEN'S INJECTING DRUG USE HEALTH CAR                                                             Closed
Public Health                   HEPATITISPREVELANCE
                   Public Health and HealthC             CHRONIC CARRIAGE
                                              Services not elsewhere classified                                                                            Closed
Basic Science                   CHRONIC HEPATITISVIRAL CLEARANCE
                   Medical Virology                       C
                                            IMMUNOPATHOGENESIS                                                                                             Closed
Public Health                   H
                   Epidemiology EPATITISASIAN WOMEN      QUALITY OF LIFE                                                                                   Closed
Basic Science                   HEPADNAVIRIS PERSISTENCE OF INFECTION
                   Medical Virology         VIRAL        OUTCOMEPCR AMPLIFICATION                                                                          Closed
                   Infectious Diseases        C VIRUS CLINICAL
Clinical Medicine and Science HEPATITISPRIMARY INFECTIONVIRAL CLEARANCE                                                                                    Closed
                   Medical Virology         hepatitis C protection vaccine
Clinical Medicine and Science cell-mediated immunityvirus                                     hepatitis C infection virus persistence
                                                                                  virus-like particle     liver disease                                    Closed
Basic Science                   Assembly of flavivirus particles replication usingforof flavivirus of a model C virusvitro replication system for hepatitis C virus
                   Medical Virology                       of membranes induced by Kunjin Australian Creating a Targets for design of antiviral chemotherapy
                                                                                  Roles replicationas hepatitis
                                                                                               virus induced membranes related flavivirus infections Closed
                                            Biogenesis Flavivirus Helper system flavivirus infectionencephalitisin     and
Basic Science                   Encapsidation
                   Medical Virology         Hepadnavirus replicationRNA packaging
                                                         Pre-genomic              Viral recombination Liver disease   Persistent hepatitis B virus infection
                                                                      Reverse Transcription Design of antiviral therapies          Viral recombination Closed
Public Health                   e           m
                   Epidemiology thnography olecular epidemiology analysis
                                                         social network                                    virus      prevention of transmission
                                                                                              Hepatitis C injecting drug use                               Closed
Basic Science                   targets for antiviral therapy of hepatitis B virus topogenesis
                   Medical Virology                      viral fusion
                                            viral envelope protein assembly and                           hepatitis B targets for antiviral therapy of hepatitis B infection
                                                                                              chronic viral infection virus infection                      Closed
Basic Science                   not elsewhere classified
                                            Liver and autoimmunity
                   Immunology CD8 T lymphocytes hepatocytes tolerance transgenic mice         Hepatocarcinomas
                                                                                                          autoimmune and viral Hepatitis
                                                                                                                                   transplantation
                                                                                                                      liver autoimmune diseases            Closed
Public Health                   Access to health care Hepatitis C Men's Health
                                            Health promotion
                   Public Health and Health Services not elsewhere classified     Stigma of HCV
                                                                                              Hepatitis C Injecting Drug Use       S                       Closed
                                                                                                                      Men's healthocial and Behavioural Research
Basic Science                   not elsewhere classified
                                            Liver and suppression
                   Immunology CD8 T lymphocytes hepatocytes tolerance/autoimmunitytransgenic mice
                                                                                              Hepatocarcinomas
                                                                                                          autoimmune and viral Hepatitis
                                                                                                                                   transplantation
                                                                                                                      liver autoimmune diseases            Closed
Basic Science                               Hepatic stellate cells tissuechronic hepatitis, fibrosis, cirrhosis
                                                         Pathogenesis of                      extracellular matrix Hepatitis B Hepatitis C hepatocellular carcinoma
                   Hepatology Cell surface peptidases and gelatinases remodelling andChronic hepatitis    Cirrhosis                                         Closed
                   Hepatology               gene expression profiling
                                                         inflammation
Clinical Medicine and Science Pathogenesis of chronic hepatitis, fibrosis, cirrhosis         autoimmune hepatitis hepatitis C virus infection carcinoma
                                                                                                          chronic hepatitis        hepatocellular cirrhosis
                                                                                                                                                liver       Closed
                   Medical and Health immunology elsewhere classified drug clearance
                                            Exposed Hepatitis C virus  injecting Viral
Clinical Medicine and Science CellularSciences not seronegative Thalassaemia users                                                                          Closed
Basic Science                   Chronic viral infectionepithelia
                   Medical Virology         Polarized Transcytosis    Viral pathogenesis
                                                                                 Virus release
                                                                                             Chronic hepatitis B hepatitis C transmitted Viral infections
                                                                                                          Chronic                               hepatitis Closed
                                                                                                                      Enterically Viral hepatitis
Basic Science      Not AllocatedN/A                                                                                                                         Closed
Basic Science                   Hepatitis C Membrane Viral glycoproteins
                   Medical Virology          virus       fusion                                           Hepatitis C Hepatocelullar carcinoma
                                                                                                                       virus infection
                                                                                             Chronic disease caused by hepatitis C virus infection          Closed
Public Health                   Blood       Illness
                   Health Promotion awareness prevention and research
                                                         Qualitative health education                     HIV         Hepatitis C Injecting drug use
                                                                                             Blood borne communicable diseases                              Closed
Basic Science                   Ability
                   Medical Virology of viral variants tophenotype
                                            Altered viral cause disease
                                                         Cytopathic variants B virus infection
                                                                      Hepatitis              Extrahepatic disease Viral hepatitis
                                                                                                          Liver disease                                     Closed
Basic Science                   Prime-boost protocols DNA vaccination
                   Medical Virology         Antiviral therapy         Hepadnavirus infection
                                                                                 Immune therapy
                                                                                             Antiviral therapy        Hepatitis
                                                                                                          Chronic liver diseaseB virus infection            Closed
Basic Science                    and Cell Biology mice
                   BiochemistryCre/lox transgenicnot type III receptor
                                            TGF beta elsewhere classified
                                                         hepatocarcinogenesis
                                                                      hepatocyte                                      liver fibrosis
                                                                                             hepatitis hepatocarcinogenesis metastasis                      Closed
                   Transplantation Immunologyhepatitis Hepatitis C Immunopathogenesis
Clinical Medicine and Science Cholestatic Gene Expression              Virus     Liver Transplantation                                                      Closed
Basic Science                   antiviral agents
                   Medical Virology         recombinant baculovirus
                                                         virus replication                                                         liver diseaseiral
                                                                                                                                                v
                                                                                             cirrhosis hepatitis C hepatocellular carcinoma hepatitis       Closed
Public Health                   B           Harm reduction
                   Epidemiology lood-borne viruses Hepatitis Illict drugs Social determinants                                                               Closed
                   Infectious Diseases      Hepatitis B Human
                                                         virus
Clinical Medicine and Science Antiviral Resistance Mutations Immunodeficiency Virus AIDS
                                                                      Therapeutics                                    Cirrhosis Hepatocellular carcinoma
                                                                                                          Acute Hepatitis                                   Closed
                                                                                                                                                Liver transplantation
                   Hepatology                             Virus       Oxidative stress
                                                                                 Viral       Disease Hepatitis C related liver disease Therapeutic Intervention, new targets
Clinical Medicine and Science Gene ArrayHepatitis C Hepatocellular Carcinoma Pathogenesis pathogenesis Hepatocellular Carcinoma                             Closed
                                                                                                                                   Therapeutic Intervention, antioxidants
Basic Science                   hepatitis lamivudine replication fitness
                   Medical Virology                                                                                                                         Closed
                   Hepatology
Clinical Medicine and Science angiotensinhepatic fibrosishepatitis C                                      hepatitis C hepatocellular cancer primary biliary cirrhosis
                                                                                             hepatic fibrosis                      liver transplantation Closed
Basic Science      Medical Virology
                                Delivery of a variety of Induction of anti-HCV immune response
                                            Development of chimeric virus-like particles (VLPs)
                                                          foreign epitopes                                HCV: a major human pathogen inducing severevirus-like particles
                                                                                                                      Immunisation procedures based on liver disease
                                                                                             Development of HCV vaccine                                     Closed
Public Health                    Dietetics hepatitis obesity
                   Nutrition anddiet                                  steatosis treatment                                                                   Closed
                   Gastroenterology and Hepatitis
Clinical Medicine and Science Cirrhosis Hepatology Liver Cancer       Nutrition Osteoporosis                                                                Closed
                   Infectious Diseases
Clinical Medicine and Science Hepatitis C Immune responseRisk factors            Viral       Hepatitis
                                                                      Transmission quasispecies C Incarceration       Injecting drug use                    Closed
Public Health                   Attitudes/Behavior Care
                                            Health
                   Social and Community Psychology experiences                                                                                              Closed
Public Health      Public Health and Health Services not care for Health providers settings people with hepatitis C
                                Barriers to primary health elsewhere classifiedfor people Dental careHepatitis C Injecting drug use
                                            Discrimination by health care careHealth careinjecting drugs
                                                         Discrimination in health hepatitis C for
                                                                      people with care                                             Nursing                  Closed
                                                                                                                                                Primary health care
Public Health      Not Allocated            hepatitis C risk practices
                                health outcomes homelessness young people                                                                                   Closed
Basic Science                   Hepatitis B Hepatitis C Modified virus-like particles of foreign epitopes
                   Medical Virology                       virus                  Vaccine
                                            virus envelope protein Platform delivery                                                                        Closed
                   Gastroenterology and Hepatology Liver
                                            Hepatocytes
Clinical Medicine and Science Gastroenterology                                               Chronic      Chronic liver injury
                                                                      Nonalcoholic steatohepatitis liver disease Hepatitis Hepatocellular injury Closed
Basic Science                   hepatocarcinogenesis liver regeneration
                                            inflammatory cytokinesliver stem cells
                   Cell Development (incl. Cell Division and Apoptosis)                      alcohol      cancer                   v
                                                                                                                      liver diseaseiral hepatitis           Closed
Basic Science                               cellular immune response
                   Hepatology acute infection            hepatitis C immunology  liver                                                                      Closed
Public Health                               Hepatitis                 knowledge risk beliefs
                                                                                  and
                   Family Care Antenatal screening B health services utilisation factors                                                                    Closed
Basic Science                   Autoimmunity                          Tolerance Transplantation
                   Cellular Immunology Hepatitis T Lymphocytes Transgenic Mice                                                                              Closed
                   Gastroenterology
Clinical Medicine and Science HCV           HGV          HIV          Infect                                                                                Closed
Public Health                   hepatitis C qualitative not elsewhere classified
                                                         reproduction
                   Public Health and Health Services research service utilisationwomen's health
                                                                                             contraception addiction
                                                                                                          drug        hepatitis C                           Closed
                   Medical Virology                                   Viral immunity
Clinical Medicine and Science HIV/AIDS Hepatitis B Vaccine Development Virus-like particle                                                                  Closed
Basic Science                   Pathogenesishepatic cell function
                   Gastroenterology and Hepatology hepatologypeptidases tissue remodelling andLiver diseases hepatitis C virus infection
                                                                                             Chronic disease caused matrix inflammation fibrosis
                                                                                                           extracellular by
                                                                                                                      cirrhosis                 liver       Closed
Basic Science                   Drug        Hepatitis B Nucleoside Precore mutation
                   Medical Virology resistant mutations                analogues Replication fitness                                                        Closed
Basic Science                   envelope glycoprotein hepatitis C membrane virus entry and replication
                   Medical Virology         flavivirus                           fusion                               virus
                                                                                             flavivirus hepatitis C Virus infection                         Closed
Public Health                   Hepatitis C injecting drug elsewhere classified health
                                                         injection international
                   Public Health and Health Services notuse safety                                                                                          Closed
Public Health                   BBV         Blood-borne virus
                                                         IDU          prevention
                   Public Health and Health Services not elsewhere classified                                                                               Closed
Basic Science                   Hepatitis C dipeptidyl pepidases inmatrixdefinciency remodelling
                   Gastroenterology                                                liver disease
                                                         extracellular vitro and tissue of gene products                                                      Closed
Public Health                   epidemiologyethnography  injecting drug classified
                                                                      public
                   Public Health and Health Services not elsewhere use healthexual health
                                                                                   s                         injecting drug use
                                                                                                                         risk diseasess
                                                                                                blood borne communicablecontextsexual health      young peopleClosed
Basic Science                   antiviral agents
                   Medical Virology         hepacivirushepatitis viroporin virus replication                                          liver disease
                                                                                                cirrhosis hepatitis hepatocellular carcinoma                  Closed
Public Health                   g           hepatitis C immune response
                   Epidemiology enetic testing                                       study
                                                                      longitudinalviral persistence
                                                                                                epidemiology             hepatitis C virus infection persistence
                                                                                                             genetic testing                      viral
                                                                                                                                      immune responses        Closed
Public Health                   Vietnamese Services not elsewhere environment
                                            blood        ethnography
                   Public Health and Health IDU borne disease riskclassified                                                                                  Closed
                   Cellular Immunology
Clinical Medicine and Science Hepatitis B Viral immunity immunopathology                                                                                      Closed
Public Health                   Hepatitis C adherence injecting drug classified
                                                                      medical      patient
                   Public Health and Health Services not elsewhere use treatment recruitment                                                                  Closed
                   Immunogenetics
Clinical Medicine and Science MHC                        lymphocytes
                                            cytotoxic T escape mutantshepatitis C leucocyte membrane molecules disease progression the immuneClosed
                                                                                                HCV related pathogenesis
                                                                                                             HLA typing               evasion of viral persistence
                                                                                                                                                               system
Basic Science                   HAART
                   Medical Virology         HIV          Hepatitis fibrosis                                                                                   Closed
                   Medical Virology
Clinical Medicine and Science Hepatitis C                                                                                                                     Closed
Public Health                   H            virus
                   Epidemiology epatitis C drug treatment             pegylated interferon
                                                         injecting drug use                                                                                   Paying
                   Gastroenterology and hepatic fibrosis
Clinical Medicine and Science apoptosis Hepatology hepatic steatosis  hepatocyte proliferation  NAFLD                                 obesity
                                                                                                             hepatitis C nonalcoholic steatohepatitis         Closed
                   Hepatology
Clinical Medicine and Science apoptosis hepatic fibrosis              hepatitis C hepatocyte proliferation
                                                         hepatic steatosis                                                                                    Closed
                   Hepatology               Hepatitis C Pathogenesis of autoimmune cell biology fatty mechanisms of hepatic fi
                                                          fibrotic injury
                                                                      Pathogenesis of non-alcoholic and liver disorder
Clinical Medicine and Science Hepatic ischaemia reperfusionprogression Stellatehepatitis                                                                      Closed
Basic Science                   Fatty
                   Medical Virology liver Hepacivirus                              Hyperlipidemia
                                                         Hepatitis C Hepatitis viruses                                                                        Closed
                   Endocrinology            Insulin Restistance
Clinical Medicine and Science Chronic Hepatitis C virus  Steatosis body compositionviral genotype                                                             Closed
Basic Science      Medical Virology
                                Evolution of viral sequences
                                            Immune evasion
                                                         Neutralizing antibody responses Ability to clear HCV infectioninfection
                                                                      Viral glycoprotein function            Development of chronic HCV infection
                                                                                                                         HCV                                  Closed
                   Biotechnology not elsewhere trials epititis C virus
                                            Clinical
Clinical Medicine and Science Cellular ImmunityclassifiedH                         Vaccines
                                                                      Preclinical immunogenicity                                                              Paying
Public Health                   B
                   Epidemiology iostatistics             Virus        Seroprevalence
                                            Hepatitis B Mathematical model molecular virology                                                                 Closed
                   Cellular Immunology HIV vaccine development
                                                         Hepatitis C InteractionsPharmacogenetics thedrug hypersensitivity reaction
                                                                       disease       between HIV and of human host immune
Clinical Medicine and Science Complications of antiretroviral drug therapypathogenesis                                                                        Paying
Basic Science                   anti-viral chemokines
                   Medical Virology                                   interferon microarray
                                                         hepatitis C virus                                                                                    Closed
                   Infectious Diseases
Clinical Medicine and Science Epidemiology               Immunisation
                                            Health Policy and Sevices evaluation
                                                                      Population Prevention Hepatitis B Hepatitis B Immune response
                                                                                   health                                carrier mothers
                                                                                                                                      Indigenous health       Closed
                   Gastroenterology and Hepatic Stellate Cells virus replication    oxidative stress
                                                                                                alcoholic liver disease hepatic
                                                                                                             gene                     viral
Clinical Medicine and Science Cyp2e1 Hepatology Hepatitis C alcoholand anti-viral action of interferon expression fibrosis hepatitis replication  viral       Closed
                   Medical Virology          virus
Clinical Medicine and Science Hepatitis C chemokines     gene expression
                                                                      transcriptional regulation
                                                                                   viral hepatitis
                                                                                                Hepatitis C hepatitis inflammation
                                                                                                              virus                   liver                   Closed
                   Infectious Diseases      H             virus
Clinical Medicine and Science Chemokines epatitis C Inflammation      Liver                                  Hepatitis infection
                                                                                                Chronic liver injury C Inflammatory mediators and the liver   Closed
Public Health                   Hepatitis C ethnicity injecting drug classified
                                                                      social
                   Public Health and Health Services not elsewhere useresearch     treatment                                                                  Closed
                   Hepatology
Clinical Medicine and Science Hepatitis C Liver disease               Obesity
                                                         Metabolic syndrome Steatosis                                                                         Paying
Basic Science                   hepatitis
                   Cellular Immunology B immunotherapy                virology
                                                         vaccine development virus-like particleand VLP Vaccinesurface antigen
                                                                                                DNA                                   immunotherapy
                                                                                                             hepatitis B immunity-cellular                    Closed
                                                                                                                                                  vaccine vectors
                   Hepatology               Hepatic fibrosis           disease C Viral hepatitis
Clinical Medicine and Science Chronic liver disease Hepatitis C Heptatis progression Chronic hepatitis C     Cirrhosis Hepatitis                              Closed
                   Biotechnology not elsewhere classified and procedures vaccine technology
                                            Diagnostic tests
                                                         Immunity infection
Clinical Medicine and Science Antiviral, Viral Hepatitis; VirologytoVaccine development, Diagnostic Assay                                                     Paying
Basic Science                   hepatitis C virus
                   Medical Virology                      liver
                                            infectious disease                                               immune priming
                                                                                                cell mediated immunityimmune response                         Closed
Basic Science                   membrane protein structureglycoproteins
                   Medical Virology         fusion       viral        virus entry and replication
                                                                                   virus receptors
                                                                                                Hepatitis C understanding virus-host interactions
                                                                                                                         viral infection                      Closed
Basic Science                   viral       viral fusion
                   Medical Virology entry mechanismsvirology of hepatitis B virus                            hepatitis B virus B virus
                                                                                                                         liver infection
                                                                                                chronic carriers of hepatitis cancer                          Closed
Basic Science                   Cellular receptors
                   Medical Virology                      m
                                            biochemical olecules tiggers                                                                                      Paying
                   Medical      E2 glycoprotein
Health Services Research Virology                                     Viral fusion
                                            Hepatitis C Receptor binding                                                                                      Paying
                   Cellular Immunology Cellular immunology Viral clearance
Clinical Medicine and Science Acute Hepatitis C infectionImmunopathogenesis                                                                                   Paying
Basic Science                   Hepatitus C Virus
                   Medical Virology                      fusion
                                            Membrane Viral glycoproteins                                                                                      Paying
Basic Science                   DNA
                   Medical Virology vaccine Vaccine development, hepatitis of B-cell and CTL epitopes of hepatitis C B control vaccine
                                                         Virus-like particle C influenza Development
                                                                       delivery                                           and and Vaccine
                                                                                                             Hepatitis C Infection influenza strategy         Closed
Basic Science                   Antibodies Diagnostic Test
                   Medical Virology                                     Virus Infection
                                                         Hepatitis C Humoral Immunity                                    Hepatitis                Immune Response
                                                                                                Antibody Diagnostic Assay C Humoral Immunology Closed
Basic Science                   Covalently closed circular DNAeffects
                   Infectious Diseases      Cytokine mediated
                                                         HepatocyteHistologicalInverse nested PCR Liver disease
                                                                        death and proliferation
                                                                                     techniques Hepatocellular carcinoma              of hepatitis chronic infection
                                                                                                                                                               Closed
                                                                                                                         Resolution Therapy forB virus infection
                   Hepatology                            Humoral and cellular immunity
                                                                                    Recombinant
Clinical Medicine and Science Antiviral Duck hepatitis B virus Prime-boost vaccination fowlpoxviruses hepatitis B virus disease Vaccine development
                                                                                                Antiviral therapy
                                                                                                             Chronic                  Immunotherapy
                                                                                                                         Chronic liver infection               Closed
                   Hepatology                proliferation
                                                         In            Inverse
Clinical Medicine and Science HepatocyteHepatocytes situ hybridization nested PCR Chronic hepatitis B virus infection Viral hepatitis
                                                                                    Viral persistence                      the liver
                                                                                                             Cirrhosis ofHepatocellular carcinoma              Closed
                                                                                                                                                  Viral-induced cancer/oncogenesis
                   Infectious Diseases      epitope mapping            vaccine development hepatitis C infectious diseases development
Clinical Medicine and Science dendritic cell targeting synthetic lipopeptides                                            vaccine      viral immunity           Closed
                   Infectious Diseases      chronic hepatitis B;care
                                                         clinical HIV  heapatitis with hepatitis HIV-AIDS; therapy
Clinical Medicine and Science acute hepatitis, chronic hepatitis C of personC; hepatitis B; C                                                                  Paying
                   Hepatology               hepatic
Clinical Medicine and Science ductular reaction fibrosis hepatic progenitor cells                            fatty liver hemochromatosis insulin resistance
                                                                                                chronic liver disease disease         hepatic     hepatitis C Closed
Basic Science                   CD8+ T      Liver                                   mice
                   Cellular Immunology lymphocytes Tolerance Transgenic Transplantation         Hepatocarcinomas
                                                                                                             autoimmune and viral Hepatitis
                                                                                                                                      transplantation
                                                                                                                         liver autoimmune diseases             Closed
                   Infectious Diseases      Anti-viral Chronic         HIV-AIDS, Immunology,
Clinical Medicine and Science Anti-viral immunity therapy hepatitis B Hepatitis B Viral persistence                                                            Paying
Basic Science                   Hepatitis                Innate Immunity
                   Infectious Diseases B Immunosuppression Signaling pathways receptors B Immunomodulation
                                                                                    Toll-like   Hepatitis Virus InfectionInflammation Sepsis                   Paying
                   Hepatology                             Liver Disease
Clinical Medicine and Science Bile acids Cholestatic Hepatic Fibrosis  Hepatic Stellate Cell
                                                                                    PaediatricsBiliary Atresia
                                                                                                             Cholangiopathy Fibrosis Liver Disease Hepatitis
                                                                                                                         Cystic                   Liver Transplantation
                                                                                                                                      Idiopathic Neonatal Paying
                   Gastroenterology and Hepatology liver cancer
                                            hepatitis B
Clinical Medicine and Science hepatic fibrosis                                                                                                                 Paying
                   Medical Virology
Clinical Medicine and Science Antiviral Gene Expression                 Virus                                 Virus      interferon therapy HCV
                                                         Hepatitis C Interferon microarray Hepatitis C Host antiviral responseliver disease                    Paying
                   Immunology not elsewhere classified
                                            caused by hepatitis hepatitis,influenza,reproduction, infectious
                                                         diseases,infection control,chronic disease
Clinical Medicine and Science Vaccine development,antigen presentation,viral                                                                                   Paying
Public Health                   acceptability Services injecting drug classified
                                            h
                   Public Health and Health epatitis B not elsewhere use
                                                                       prevention vaccinationhepatitis B immunisation diseaserevention of infectious disease
                                                                                                                         liver        p           substance usePaying
                   Infectious Diseases      Chronic fatigue syndrome
Clinical Medicine and Science Cellular immunology Genetics Hepatitis C Neuroimaging                                                                            Paying
Public Health                   Public health
                                            Qualitative research Social determinants of health
                                                         Risk behaviour
                   Public Health and Health Services not elsewhere classified                                                                                  Paying
Basic Science                   h           immune response
                   Epidemiology epatitis C virus                       proteasomes  statistics
                                                         population genetics and evolution                                                                     Paying
                   Infectious Diseases
Clinical Medicine and Science HIV-AIDS Hepatitis C immune response     immunity vaccines                                                                       Paying
                   Hepatology               hepatitis c insulin resistance
Clinical Medicine and Science antiviral therapy                        interferon signaling
                                                                                    obesity                              interferon - obesity treatment
                                                                                                hepatitis c insulin resistance        ribavirin                Paying
                   Hepatology                            Lifestyle Liver
Clinical Medicine and Science Cytokine Insulin resistance factors                   Obesity     Hepatic insulin resistance
                                                                                                             Hepatitis C exercise trainingliver disease
                                                                                                                                      fatty                    Paying
                                                                                                                                                  obesity-metabolism
                   Clinical Sciences not elsewhere classified care of persons Alcohol C, Injecting drug use
                                            Alcoholic liver disease
                                                         Clinical                   Hepatitis
Clinical Medicine and Science Alcohol abuse and dependance Drug abuse, with hepatitis C                                                                        Paying
                   Hepatology               hepatitis
Clinical Medicine and Science exercise physiology c insulin resistance obesity      pathogenesis                                                               Paying
                   Gastroenterology and Hepatology Liver transplantation
                                            Hepatitis C
Clinical Medicine and Science Cell mediated immunity                   Viral Immunology                      Cirrhosis Liver diseases transplantation Paying
                                                                                                                                      Liver       Primary
                                                                                                Chronic disease caused by hepatitis C virus infection hepatocellular carcinoma
Basic Science                               inflammatory cytokines
                                                         liver cell lineage commitment
                                                                                    stem cells
                   Hepatology hepatocytes and cholangiocytes liver progenitor cells cell therapychronic liver disease    viral hepatitis, HBV and HCV          Paying
                   Gastroenterology                                    Stem cells
Clinical Medicine and Science Hepatitis B Hepatitis C Liver progenitor cells Tissue regeneration                                                               Closed
Basic Science                   hepatitis                immune response
                   Infectious Diseases C humoral immunology vaccine development     virus like particle                                                        Paying
                   Hepatology
Clinical Medicine and Science antiviral                                prophylaxisviral immunology
                                            hepatitis B liver transplantation                                                                                  Closed
                   Infectious Diseases      Perinatal transmission
                                                         Viral hepatitis
Clinical Medicine and Science Immunological changes in pregnancy                                                                                               Paying
Basic Science                   Antibody Hepatitis C envelope glycoprotein
                   Medical Virology                       Virus        viral fusion             acute hepatitis
                                                                                                             chronic disease caused by hepatitis infectious disease
                                                                                                                                      prevention of C virus infection
                                                                                                                                                  viral hepatitis
                                                                                                                         development of HCV vaccine            Paying
Basic Science                   Fc Receptors
                   Infectious Diseases      HIV-AIDS NK cells macrophages           monocytes HAART-AIDS pathogenesis C Immune Reconstitution Disease
                                                                                                             HIV         Hepatitis                immune dysfunction
                                                                                                                                                               Paying
                   Medical Virology         infectious disease
Clinical Medicine and Science hepatitis C virus          liver                                               immune response.
                                                                                                cell mediated immunityneutralising antibody                    Paying
                   Gastroenterology and Hepatology disease
                                            infectious liver
Clinical Medicine and Science hepatitis C virus                        therapy                               cell therapyimmune response.
                                                                                                cell mediated immunity                             antibody Paying
                                                                                                                                      neutralisingviral clearance
                   Infectious Diseases      drug resistance
Clinical Medicine and Science HIV-HBV co-infection hepatic fibrosis    hepatotoxicity                                                                          Paying
                   Gastroenterology and genetic polymorphisms
Clinical Medicine and Science cirrhosis Hepatology hepatitis C pharmacogenomics                                                                                Paying
Basic Science                   Cellular    Hepatits Innate
                   Cellular Immunology immunity C virus immunity                                                                                               Paying
Public Health                   h                        molecular epidemiology
                                                                       sexual
                   Epidemiology epatitis C men who have sex with men transmission acute hepatitis C          hepatitis C sexually transmitted infections       Paying
                   Clinical Sciences not elsewhere transmitted
                                            Sexually Viral hepatitis
Clinical Medicine and Science Aboriginal health classified infections                                                                                          Paying
                   Health        Addiction Health outcomes             Hepatitis C Opioid dependence
Health Services Research and Community Services Health policy and services evaluation                                                                         Paying
Public Health                    Indigenous hepatitis C mathematical classified
                                               Australians
                   Public Health and Health Services not elsewhere modelling
                                                                       prison population
                                                                                   qualitative research Health hepatitis C delivery health issue
                                                                                                Aboriginal chronic      service infection
                                                                                                                                    social                    Paying
Basic Science                    viral        virus entry and replication
                   Medical Virology glycoproteins          virus receptors                                  Hepatitis C Virus replication
                                                                                                Chronic infection                                             Paying
Public Health                    c
                   Epidemiology ohort studies              molecular epidemiology epidemiology
                                              injecting drug use                   viral
                                                                       social netword hepatitis                                                               Paying
Public Health                    Prison populations
                                              drug use health servcie utilisation hepatitis
                                                                       risk behaviour
                   Public Health and Health Services not elsewhere classified      viral                                                                      Paying
Basic Science                    Chronic hepatitis C virus infection Interferon Virus Replication
                   Medical Virology                        Innate Immunity
                                              Infectious Diseases                                                                                             Paying
Basic Science                    Hepatic Fibrosis
                                              Hepatitis C               Apoptosis Liver Transplantation
                   Gastroenterology and Hepatology HepatocyteImmunosuppression                                                                                Paying
Public Health                    Economic Services
                                              Health outcomes
                   Health and Community evaluation Health policy and services evaluation
                                                                       Hepatitis C Mathematical modelling disease Health services
                                                                                                Chronic liver
                                                                                                            Health outcomes                       virus infection
                                                                                                                                                              health
                                                                                                                                    Hepatitis C Population Paying
Public Health                    cohort studies
                                              hepatitis C injecting drug classifiedcontrolled development of HCV vaccine drug use
                   Public Health and Health Services not elsewhere use randomised  vaccine preparedness hepatitis C injecting liver diseaserevention of infectious disease
                                                                                                 trial       studies                             p            Paying
Public Health                    Aboriginal and Islander viruses Health
                                              Blood borne HealthIslander health
                                                           Health
                   Aboriginal and Torres Strait Torres Straightpromotion services access                                                                      Paying
Basic Science                    Chronic Infection of the immunevirus infection
                   Medical Virology           evasion      hepatitis C system                                                                                 Paying
Public Health                    Epidemiology Infectious not elsewhere classified
                                                           Injecting Population Vaccines
                   Public Health and Health Servicesdiseases drug use              health                                                                     Paying
                   Infectious Diseases        HBV
Clinical Medicine and Science Chronic viral infectionsHCV              Herpes viruses                                                                         Paying
Public Health      Epidemiology               hepatitis substance use
                                 injecting drug use                    prison population health
                                                                                   mental                   infectious diseases use
                                                                                                injecting drug use                               mental
                                                                                                                        substance prison population health    Paying
Basic Science                    vaccine biology
                   Innate Immunity            dendritic cell
                                                           cytokine production hepatitis C infection vaccine technology dendritic cell
                                                                       bone marrow              adjuvant                viral immunity                        Paying
                                                                                                                                                 hepatitis C infection
                   Gastroenterology and Hepatology hepatic steatosis
                                              h
Clinical Medicine and Science liver diseaseepatitis C infection antiviral agents                            h           hepatic steatosis
                                                                                   cannabis liver diseaseepatitis C infection antiviral therapy               Paying
                   Medical and Health         hepatitis elsewhere classified syndrome disease C virus liver disease
                                                           lifestyle
Clinical Medicine and Science liver Sciences notC infectionfactors     metabolic fatty liver hepatitis fatty            fibrosis    lifestyle factors         Paying
                   Medical Virology           duck         hepatocytes
Clinical Medicine and Science hepatitis B virus hepatitis B virus viral replication persistence
                                                                                   viral                    liver disease           paracetamol toxicity Paying
                                                                                                hepatitis B infection antiviral therapy          cell proliferation
                   Infectious Diseases        drug
Clinical Medicine and Science hepatitis C virus resistance sequencing                                       drug therapy
                                                                                                hepatitis C infection resistance                              Paying
Basic Science                    virus        human
                   Medical Virology pathogenesisimmunodeficiency virus (HIV)
                                                           chronic infection
                                                                       T cells                              human       virus pathogenesis B infection C virus
                                                                                                                                    hepatitis hepatitis Paying
                                                                                   cytokines chronic infection immunodeficiency virus (HIV)
                   Gastroenterology and Hepatology liver disease                   drug         liver       h           interferon genetics
Clinical Medicine and Science hepatologyhepatitis C infection interferon (IFN) efficacy diseaseepatitis C infection (IFN)                                     Paying
                   Gastroenterology and Hepatology virus
                                              hepatitis B drug         liver
Clinical Medicine and Science hepatocellular carcinoma resistance disease                                   liver cancerhepatocellular carcinoma
                                                                                                hepatitis B infection                                         Paying
Basic Science                                               studies                drug         human       hepatitis C virus immunodeficiency virus (HIV)
                   Biostatistics biostatisticsassociationgenomics vaccine design resistance leukocyte antigen (HLA)     human                                 Paying
                   Health        hepatitis C infection prison population
                                              hepatitis
Health Services Research and Community Services B infection prevention health services research             hepatitis injecting liver disease
                                                                                                hepatitis C infection B infection drug use                    Paying
                   Gastroenterology and Hepatology proteomics translational research hepatitis C infection pharmacogenomics outcomes Paying
                                              genomics
Clinical Medicine and Science clinical research                                                             prognosis               treatment complications
Basic Science      Medical Virology
                                 human immunodeficiency virus (HIV)
                                              chronic infection
                                                           therapeutic target                               human       immune modulation B infection C virus
                                                                                                                                    hepatitis hepatitis Paying
                                                                                                chronic infection immunodeficiency virus (HIV)
                   Medical Virology           drug resistance
Clinical Medicine and Science hepatitis B infection vaccination failure                                     drug resistance
                                                                                                hepatitis B infection immunisation                            Paying
                   Infectious Diseases        human        blood-borne communicable
                                                                       virology
Clinical Medicine and Science hepatitis C virus immunodeficiency virus (HIV) diseases           hepatitis C virus immunodeficiency virus (HIV) diseases
                                                                                                            human       blood-borne communicable
                                                                                                                                    virology                  Paying
                   Immunogenetics (incl. Geneticnucleotide polymorphism (SNP)
                                              single Immunology)
Clinical Medicine and Science hepatitis C infection interferon (IFN)                                        interferon interferon (IFN)
                                                                                                hepatitis C infection non-responders                          Paying
Basic Science                    hepatitis C virus
                   Medical Virology           glycoproteinsantibody vaccine development chronic infection design
                                                                                   receptor binding         vaccine     structure-function                    Paying
Basic Science                     and Cell Biology not elsewhere classified interferon (IFN)
                                              viral
                   Biochemistryviral immunity clearance    innate immunity
                                                                       microrna                 dengue virus            hepatitis C virus
                                                                                                            influenza virus                                   Paying
Public Health                    qualitative research C virus
                   Health Promotion                                                relationships
                                              hepatitis prevention injecting drug use                                                                         Accepted
                   Medical Virology           human immunodeficiency fibrosis
                                                                       liver
Clinical Medicine and Science hepatitis B infection liver disease virus (HIV)      inflammation immunology                                                    Accepted
                   Medical Virology           antiviral agents pathogenesis
Clinical Medicine and Science hepatitis C virus            virus                   hepatitis C infection
                                                                                                liver
                                                                       host/pathogen interaction disease                                                      Paying
                   Infectious Diseases        clinical research
Clinical Medicine and Science hepatitis C infection hepatitis C virus  epidemiologyhealth services research                                                   Paying
Basic Science                    hepatitis Hepatology
                                              liver
                   Gastroenterology andC virusinjury obesity                       a
                                                                       inflammationdiposity                                                                   Accepted
                   Medical Molecular Engineering of Nucleic Acids and Proteins
                                              otitis                   hepatitis B virus
Clinical Medicine and Science Aboriginal child mediaStreptococcus pneumoniae       vaccine development                                                        Paying
Public Health                    hepatitis C virus
                                              injecting drug elsewhere
                                                           natural     treatment access to health care
                   Public Health and Health Services notuse history classified                  epidemiology                                                  Accepted
Public Health                 h
                   Epidemiology epatitis B virus
                                           hepatitis B infection molecular epidemiology
                                                       epidemiology                          communication skills burden of disease
                                                                                health literacy       health education                               Paying
                   Cancer Diagnosis        hepatocellular
                                                       hepatoma
Clinical Medicine and Science hepatocellular carcinoma cancer liver cancercancer detection screening genetics fibrosis
                                                                                             cancer   cancer      liver                  hepatitis Accepted
                                                                                                                             hepatitis C infection B infection
Basic Science                 hepatitis B infection fibrosis
                   Innate Immunity                                 stellate cells epatitis
                                           human immunodeficiency virus (HIV)   h                                                                    Paying
Basic Science                  not elsewhere classified
                                           hepatitis B infection C infection immune response
                                                       hepatitis innate immunity
                   Immunology interferon-alpha (IFN-alpha)                                                                                           Accepted
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The aim is to evaluate the efficiency of a virus-like particle (VLP) vaccine for hepatitis C virus (HCV). HCV infects about 10,000 people every year in Australia and approximately 8, 000 of thes
                   the
Flaviviruses areENDagents of many mosquito-transmitted infections such as encephalitis and dengue, and hepatitis C virus is a member of the same virus family. During virus multiplication in
                 END
Title: Structure of hepadnaviral pre-genomic RNA. We aim to study the replication strategy of human hepatitis B virus (HBV), a member of the hepadnavirus family. Hepadnaviruses infect hep
                  virus
The hepatitis C END (HCV) continues to spread among injecting drug users (IDUs) in Australia at a very high rate, despite success in preventing the spread of HIV in the same groups; the co
                 END
An estimated 350 million people worldwide, and 250,000 in Australia, are chronically infected with the hepatitis B virus (HBV). Without intervention, one third will die as a direct result of this inf
                  that
It is well known ENDtolerance to liver allografts is more readily achieved than to other organ grafts, even across a major histocompatibility (MHC) barrier. According to some experiments, prefe
                 END
This study will identify the health and social support needs of men who are infected with hepatitis C and will complement a similar study currently being conducted with women. At present, the
                 END
Acceptance of transplanted organs is currently achieved by treating the recipient with immunosuppressive drugs that block T cell responses. However, because these drugs are non-specific,
                  END
Chronic liver diseases, particularly those caused by Hepatitis B virus and Hepatitis C virus infection, are major causes of morbidity and mortality in our community. They are characterised by p
                  END
The incidence of hepatitis C virus (HCV) infection is rapidly increasing in our community. This infection cannot be prevented by vaccination and the current treatments often fail. We believe th
                  END
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                  END
The viruses causing hepatitis in man must cross specialised cell layers in the body to reach the liver, and must again cross these cell layers and liver cells in order to be transmitted to subseq
                  END
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Hepatitis C virus (HCV), the main cause of of post-transfusion and community -acquired non-A, non-B hepatitis, infects approximately 170 million humans world-wide with some 135,000 infec
                  make
This project will END a direct and major contribution to Hepatitis C prevention by addressing the need for blood awareness in prevention education. The need for measures to prevent the spr
                  END
The human hepatitis B virus (HBV) is a member of the hepadnavirus family that includes a number of other very similar host-specific viruses. Acute HBV infection can produce extreme variati
                  END
Hepatitis B virus (HBV) causes acute and persistent (chronic) infection with varying degrees of liver damage and a strong association with the development of liver cancer. Worldwide ~ 250 m
                  END
The transforming growth factor-beta (TGF-beta) family is a group of multifunctional growth factors which regulates a number of important cellular functions, including proliferation, differentiatio
                  END
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                  cause
HCV is a major END of liver disease and around 200 million people are currently infected worldwide, including 200,000 Australians. HCV differs to other flaviviruses. Most notably, around 80
                  END
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                  END
There are a number of patients throughout Victoria that are co-infected with both hepatitis B virus (HBV) and human immunodeficiency virus (HIV). These patients are currently being treated f
                  END
The majority of individuals infected with hepatitis C virus (HCV) show a slow progression of liver disease over a period of 20-30 years. There is increased scaring of the liver which can result i
                  END
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                  is a
Hepatic fibrosisENDcommon response to chronic liver injury, during which the normal liver architecture is distorted by scar tissue. Hepatic fibrosis can lead to cirrhosis and liver transplantation
                  END
Hepatitis C virus (HCV) is a major causative agent of chronic liver disease and occurs in about 1% of the world's population. HCV is a quasispecies characterised by sequence variations and
                  END
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                  provide new information to improve clinical outcomes for people with chronic liver disease. Among people referred by GPs with abnormal liver tests, two thirds have hepatitis C
This Centre will END
                  END
Hepatitis C (HCV) affects approximately 200,000 Australians, of whom a significant minority develop long term complications, including cirrhosis, liver failure and liver cancer. The dominant m
                  END
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                  END
Hepatitis C is now the leading communicable disease in Australia and stigma and discrimination have been identified as major barriers to addressing this epidemic. This study builds on our pr
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                  END
Nonalcoholic steatohepatitis (NASH) is the commonest cause for liver disease in Australia. On liver biopsy it is characterised by changes similar to that induced by alcohol, but occurs in indivi
                  END
Maintaining liver function is essential for health, and compromising this ultimately results in death. The liver is unusual, as it can regenerate to replace lost or damaged tissue. Recently it has b
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                  growing health concern, with 1% of the Australian population now HCV positive, and signs that it is increasing more quickly among women of child-bearing age. This study bui
Hepatitis C is a END
The small envelope protein of hepatitis B virus (HBsAg) can self-assemble into highly organised viruslike particles with about 150 HBsAg-proteins forming a virus-like particle (VLP). VLPs ind
                  END
                  END
Chronic liver diseases, particularly those caused by autoimmune disease, alcohol and Hepatitis B and C virus infection, are major causes of morbidity and mortality in our community. They are
                  END
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                  END
Hepatitis C Virus infects approximately 200 million people world-wide and is the major cause of liver transplantation in the Western world. At present there is no vaccine and interferon alpha is
                  END
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                  END
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National drug surveys and surveillance systems have detected sharp increases in the use of 'psychostimulant' drugs such as the amphetamines, ecstasy and cocaine. The level of harms ass
                 END
Hepatitis C virus is a major medical problem in Australia and many other parts of the world. The viruses causes a persistent infection in most infected individuals that results in serious liver dis
                 virus
The hepatitis C END (HCV) is a major public health problem affecting over 170 million people worldwide. In Australia an estimated 157,000 people have HCV and are at risk of serious diseas
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                 END
Over 200,000 Australians are infected with the Hepatitis C Virus (HCV) and about 11,000 new infections are diagnosed each year. Around 25% of people infected with HCV will clear the virus
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                 Fatty
Lay DescriptionEND liver (steatosis) is important because it increases the vulnerability of the liver to factors that trigger inflammation and fibrosis. Patients with steatosis may develop steatoh
                 END
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                 END
In humans, chronic liver diseases cause cirrhosis of the liver in some but not all individuals. This leads to protracted ill-health, complications (fluid retention in the abdomen, confusion, bloodst
                 END
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                 END
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                 END
Hepatitis C virus is a major human pathogen infecting 200 million people world-wide. Currently, there is no vaccine to prevent infection and treatment regimes are only partially effective. IInitia
                 END
This research will advance the development of a novel vaccine strategy based on duck hepatitis B virus-like particles (VLPs). These VLPs can be engineered to contain parts of other viruses
                 END
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                 END
The Centre for Clinical Immunology and Biomedical Statistics (CCIBS) represents a collaboration between Royal Perth Hospital and Murdoch University that has brought together internationa
                 END
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                 END
Hepatitis B virus (HBV) is transmitted by blood exposure or sexual contact and infection can result in chronic liver disease and liver cancer. Since 2000 Hepatitis B virus immunisation has bee
                 END
Liver disease caused by alcohol consumption and hepatitis C virus (HCV) infection are major national health problems. Liver disease caused by HCV is greatly accelerated by alcohol consum
                 END
The majority of individuals infected with hepatitis C virus (HCV) show a slow progression of liver disease over a period of 10-20 years. This liver disease is primarily a result of the host immun
                 END
The majority of patients who become infected with hepatitis C virus (HCV) are unable to mount an effective immune response and clear the virus and therefore develop lifelong (chronic) infec
                 END
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Many kinds of cancer and infections display unique proteins which the body's immune system can recognise as ' foreign', and mount an immune response which, if correctly harnessed, will ki
                 END
Hepatitis C virus (HCV) infection is a major cause of liver disease and associated deaths in Australia. HCV infection leads to progressive liver failure and may be associated with the developm
                  exploiting basic and applied research on hepatitis viruses to develop biotechnology innovations in diagnostics and vaccines for a broad range of infectious diseases
I am a virologistEND
                 END
Most individuals who are infected with hepatitis C virus (HCV) develop a persistent infection that is lifelong and are at risk of developing serious liver disease, including liver cancer. The evide
                 END
Hepatitis C virus (HCV) infects approximately 3 % of the global human population with 150,000-200,000 HCV-infected individuals currently living in Australia. Chronic HCV infection is associa
                 END
Three hundred and fifty million people worldwide and 250,000 in Australia are chronically infected with hepatitis B virus (HBV). Without intervention, one third will die as a direct result of this in
                 END
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For the induction of good immune responses, antigens should be delivered in several copies on a defined particle. The small envelope protein (HBsAg) encoded by the hepatitis B virus (HBV
The prevalenceEND  of Hepatitis C in Australia has been estimated at 242 000 people with 80% of infections acquired as a result of infection drug use. The currently available assays can be used
                  END
Though vaccination has had a major impact on the number of persons becoming infected, chronic infection with the hepatitis B virus (HBV) still remains a major worldwide problem, with 350 m
                  END
Hepatitis B virus (HBV) causes acute and chronic infection leading to severe liver damage in many patients and increased risk of primary liver cancer. Worldwide ~350 million people have chr
                  END
Infection with the hepatitis B virus (HBV) can lead to either acute resolving, or chronic HBV infection. Chronic HBV infections are often associated with severe liver disease, and increased risk
                  END
The parts of viruses, bacteria and of cancer cells that are recognised by the immune system are called epitopes. Epitopes are generated from these agents by dendritic cells which are found
                  END
I am infectious disease physician undertaking research on natural history and therapeutic strategies in viral hepatitis, including acute hepatitis C, chronic hepatitis C and chronic hepatitis B. Th
                  END
Chronic liver diseases such as hepatitis C and obesity-related fatty liver can be associated with scarring that eventually results in cirrhosis and liver failure. We are unsure why this scarring oc
                  END
The liver has paradoxical properties: it is the site of effective immune responses to pathogens, but under some circumstances, it is known to induce harmless immune responses. Poor respon
                  END
I am an infectious diseases physician and basic scientist interested in the immunopathogenesis of HIV and hepatitis B virus. My work focuses on HIV viral reservoirs and immune reconstitutio
                  END
Hepatitis B virus (HBV) infection is a major world-wide health problem, which the current treatment strategies are not ideal. Therefore understanding how HBV inteacts with the immune system
                  END
This project investigates how decreased bile flow in children's liver diseases such as cystic fibrosis and biliary atresia, leads to the release of molecules from the liver which cause recruitment
                  cause
Hepatitis B can END liver failure and cancer and affects between 90,000 and 160,000 people in Australia. Effective treatments are available but these cannot eradicate the virus. We will stu
                  END
The only treatment for hepatitis C is Interferon-ribavirin combination therapy. Interferon works by stimulating the liver cells to produce antiviral proteins that can control hepatitis C virus replica
                  END
I am an immunologist with a background in virology and peptide chemistry and my work is therefore inter-disciplinary but focused on the design of synthetic, epitope-based vaccines against in
                  END
This randomised trial will examine strategies to increase hepatitis B vaccination in drug users by comparing 1) usual clinical care; 2) enhanced outreach; and 3) financial incentive payments a
                  END
I am a clinician-scientist studying the biological determinants of clinical outcomes in infectious diseases.
                  END
This project seeks to discover how and why some injecting drug users have managed to avoid becoming infected with hepatitis C despite having injected for many years in localities in which m
                  END
Two hundred million people are infected with the Hepatitis C virus. There is no vaccine and the rate at which new strains of the virus arise enable it to evade the human immune system. This
                  END
There is an urgent need to develop therapies for treating and preventing Hepatitis B antiviral resistance, particularly in patients with advanced liver disease. Investigator-initiated clinical studie
                  END
The development of vaccines and better treatments for HIV-AIDS and Hepatitis C are urgent global health priorities. This Program will undertake studies to better understand effective immuni
                  END
The overall objective of this Research Project is to examine the mechanisms by which obesity and fatty liver impair the response to antiviral treatment in patients with chronic hepatitis C and t
                  END
The two most common types of liver disease in Australia are chronic hepatitis C (Hep C) and fatty liver disease and both result in more severe liver injury when the person is overweight. We p
                  END
I am a gastroenterologist investigating novel treatment approaches for substance abuse problems, particularly involving the gastrointestinal system
                  END
Chronic hepatitis C (CHC) infection and obesity are conditions of increasing prevalence. Untreated, CHC has significant long-term consequences including cirrhosis and liver failure, while obe
                  END
Liver diseases associated with Hepatitis C, including liver failure and liver cancer, are now the leading indication for liver transplantation globally. However, the virus re-infects the new liver an
Liver disease isENDa serious health problem. Viral hepatitis, obesity and alcohol can result in end-stage liver disease. Organ transplant is the only treatment available. A widening gap between o
                  END
The infection rate of HBV is 20% in Chinese and 10% in Australian in particularly aboriginal. The end-point of this disease is development liver failure and need functional replacement of the l
                  END
Hepatitis C virus (HCV) infects 3% of the world's population and causes an estimated 476,000 deaths per year as a result of HCV associated end-stage liver disease. HCV is one of the most
Hepatitis B virus (HBV) can cause long term health problems particularly affecting the liver and can be passed from mother to baby. Despite the availability of a HBV vaccine babies can still b
                  END
                  END
The first stage of Hepatitis C Virus replication involves attaching to liver cells. This study is aimed at understanding how the virus attaches to liver cells and how antibodies raised during infect
                  determine how viruses prevent transmission of messages within cells which orchestrate responses of our immune system to infection and whether our current therapies impro
This project will END
                  END
A successful vaccine for RNA viruses like HIV and hepatitis C (HCV) will require cell mediated immunity (CMI) as well as neutralising antibody. The vaccine delivery vehicles which are curren
                  cure
It is possible to END some patients with HCV infection but the current therapy is very costly and produces numerous side effects in treated individuals. We propose to treat patients using a ne
                  END
Chronic hepatitis B (HBV) infection may cause serious liver disease in some people, including liver failure or liver cancer. Being infected with both HBV and HIV increases the chances of thes
Chronic hepatitis C infection (CHC) causes liver failure, liver cancer and death. The treatment response rate is poor. Understanding of the factors that increase an individual’s risk of developin
                  END
                  END
Hepatitis C virus (HCV) poses a major public health problem with ~200 million people infected worldwide and no available vaccine. Injecting drug users (IDUs) are the major risk group, with 7
                  END
Hepatitis C virus (HCV) is usually transmitted by blood-to-blood contact. The risk of transmission by sexual contact has been thought to be low. However, in recent years increasing hepatitis C
                  END
This proposed new CCRE will bring together the leading Australian institution dedicated to clinical research on sexually transmitted and blood borne viral infections, and the peak organisation
                 END
Hepatitis C (HCV) treatment uptake remains extremely low in Australia (2% of 204,000 people with chronic HCV per year). Barriers to HCV treatment are greatest among recovering and curre
                 END
Despite the availability of an effective treatment for hepatitis C and the high prevalence of infection among Australian prisoners treatment uptake is extremely low. Using survey data and quali
                 END
Hepatitis C Virus infects 3% of the world's population causing recurring liver disease, cirrhosis and hepatocellular carcinoma. To infect a liver cell, the viral glycoproteins attach to cell surface
The new influenza A (H1N1) outbreak in Australia occurred at the start of the southern hemisphere flu season. The large numbers of cases in Victoria places us in a unique position to examin
                 END
                  a leading cause of liver transplants, and affects an estimated 180 million people worldwide, representing an increasing burden to the health system. This PhD focuses on how
Hepatitis C is isEND
                 END
I am a molecular virologist researching the host response to hepatitis C virus (HCV) infection with the aim of understanding how the liver clears HCV infection. An understanding of this proces
                 END
Mast cells are important in immunity. Mast cells have been implicated in asthma and more recently they have been shown to participate in immunity against bacteria, viruses and fungi. We ha
                  impact
To evaluate theEND of introducing hepatitis C virus (HCV) prevention and treatment strategies on the burden of hepatitis C in Australia through mathematical transmission models and hea
                 END
Injecting drug users (IDU) are a key target group for new vaccines designed to prevent hepatitis C virus (HCV) infection. This study will establish the feasibility of conducting HCV vaccine trial
Despite Australia’s successful hepatitis B vaccination campaign for infants many Australians are still vulnerable to the virus, including Indigenous communities. This project seeks to discover
                 END
Hepatitis C virus (HCV), a major cause of hepatitis and liver failure is a very significant global problem with approximately 3% of the world’s population infected and the rate of new cases incre
                 END
                 END
GSAO is an Australian anti-cancer drug that is currently being trialed in cancer patients. It is a mitochondrial poison that stops tumours from making blood vessels, which they need to grow an
                   and
HIV, Hepatitis BEND Hepatitis C are major health issues, especially to indigenous people. Finding effective cures is a global priority. Current therapy is expensive and fails to cure these disea
Injecting drug use (IDU) is a disproportionately large source of health and social harm. This CRE unites Australia’s leading scientists in the IDU field – researchers working on blood-borne viru
                 END
                 END
Dendritic cells (DC) are rare cells that are crucial in response to infection and surveillance of damaged tissues. We aim to understand the tools that are expressed by DC that allow them to se
                 END
Hormones related to cannabis help to regulate fat stores in the human body. CB1 antagonists are a new class of drugs that block these hormones and are being tested for the treatment of ob
                 END
The overall objective of my research activity is to examine in human subjects, the mechanisms by which obesity and fatty liver impair the response of the liver to injury and inflammation from m
                 END
Worldwide >360 million people have chronic hepatitis B virus (HBV) infection that imparts a 25% lifetime risk of death due to serious liver disease. Current therapies for chronic HBV reduce le
                 END
Hepatitis C therapy in the future is likely to involve the use of Directly Acting Antivirals, which offer a better chance of treatment success and shorter treatment courses. The downside to these
                 END
Our robust ability to mount an immune response and clear infections is tempered by the possibility of promoting autoimmunity. Several host genes regulate immunity. Viruses like HIV have ex
                 END
About 3% of the world population is currently infected with hepatitis C virus (HCV). Most have chronic infection with a high risk for progressive liver fibrosis and subsequent liver cirrhosis and
                 END
We aim to investigate the consequences of long-term therapy for hepatitis B on liver cancer progression. We propose that antiviral therapy is associated with persistent expression and accum
                 END
Viruses such as HIV or Hepatitis B or C may escape detection, and hence control, by the human host immune system through strategic mutations. This project aims to develop statistical met
                 C infection rates remain very high in some Australian populations, notably prisoners. As this group cycles frequently back to the general community, prevention of transmission
Hepatitis B and END
                 END
Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will inves
                 END
Chronic infections produced by pathogens such as HIV, overwhelm our immune system leading to an exhausted state where cells responsible for the clearance of invading microorganisms ar
“Antiviral drug-associated vaccine escape mutants” have the potential to jeopardize the hepatitis B immunization program. Which particular viral mutations or combination of mutations that ca
                 END
                 END
Hepatitis C affects between 1-3% of Australians. Currently, there is no effective vaccine and only 30% will spontaneously clear infection, while the remained develop a chronic disease with a
An estimated 3% of the world’s population is infected with hepatitis C virus (HCV). With low spontaneous clearance rates and often a poor response to treatment many infected individuals wil
                 END
                 END
Hepatitis C Virus infects 200 million people world-wide with over 200,000 Australians infected with the disease. This project will examine how the surface proteins of HCV change their shape
                 END
microRNAs (miRNAs) constitute a novel mechanism used by cells and viruses to regulate gene expression. Studies carried out in non-human primates demonstrated great potential for miRNA
Transmission ofEND hepatitis C among people who inject drugs occurs primarily as a result of sharing of equipment used to inject drugs, the majority of which occurs between intimate couples. Ho
                 END
Morbidity and mortality secondary to liver disease is greatly increased in people co-infected with HIV and HBV compared to those infected with HBV alone. Mortality remains elevated even aft
                 END
Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host pro
                 my Practitioner Fellowship will continue to facilitate an expanding program of epidemiological and clinical research in viral hepatitis, with a primary focus on hepatitis C. New di
The renewal of END
                 END
Presently, liver disease from chronic hepatitis C and obesity represents a major health problem. Overall, approximately 50% of Australians with chronic hepatitis C are obese and these patien
                 END
Australian Indigenous children suffer abormally high levels of middle ear infections (term otitis media). In many cases the infections become chronic and have a severe dischage. We propose
                  majority of hepatitis C is acquired by injecting drug users (IDUs). Given the asymptomatic nature of infection and difficulties in identifying and following those at risk of acquirin
In Australia, theEND
                END
I am an Infectious Diseases doctor working with Hepatitis B in the Top End of the Northern Territory. I will provide detailed information about the prevelance of Hepatitis B infection, the specifi
                END
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and worldwide is the third and fifth leading cause of cancer death in men and women respectively. Early diagnosis is
                END
Liver related mortality is the commonest cause of non-AIDS death in HIV infected individuals on treatment. With HIV, HBV liver damage is accelerated and liver-related mortality increased. Un
                END
Despite recent advances in therapeutic options, chronic viral infections, including infection with hepatitis C virus and hepatitis B virus, continue to be a significant cause of morbidity and morta
NHMRC FUNDED RESEARCH INTO HEPATITIS B ISSUES 2000-2012
Keywords: Hepatitis (reviewed for viral Hepatitis), HEP, Hepatitis B, HEP B, HBV
Report Run: 3 July 08/19 Mar 09/10 Mar 10/28 Feb 11/7 May 12
Sources: Extracted from NHMRC Databases -RGMS/ RMIS/GMS as at May 12
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with the disease area of Hepatitis B (Hep
B) through search of the Chief Investigator provided keyword and titles contained in the NHMRC research database. Relevance to the research area in question may
be either immediate or be a longer term perceived benefit. This dataset was current as at 7 May 12 but is subject to change over time.
Summary of Expenditure: Hepatitis B
     2000              $523,050 Actual Expenditure            8 grants
     2001              $818,860 Actual Expenditure            11 grants
     2002              $765,251 Actual Expenditure            10 grants
     2003            $1,194,936 Actual Expenditure            12 grants
     2004              $816,003 Actual Expenditure            9 grants
     2005              $803,108 Actual Expenditure            9 grants
     2006              $952,671 Actual Expenditure            9 grants
     2007            $1,296,876 Actual Expenditure            14 grants
     2008            $1,913,199 Actual Expenditure            18 grants
     2009            $2,304,704 Actual Expenditure            18 grants
     2010            $1,769,947 Actual Expenditure            14 grants
     2011            $2,139,017 Actual Expenditure            16 grants
     2012            $2,639,800 Forecast Expenditure          20 grants
    Total          $17,937,422 As at Dec 12
     2013           $2,260,115 Forward commitments            16 grants
     2014             $470,218 Forward commitments            5 grants
     2015             $173,324 Forward commitments            2 grants
     Total         $20,841,079 Out years
2. Forward commitments funding data for out-years (ie beyond 2012) is subject to change when new grants are awarded in subsequent years
 Grant Id       CIA Full Name                  Grant Type                  Grant Subtype              Scientific Title        Simplified Title        Admin Institutution       State
   967008   A/Pr Karen Vickery        CARG                                                       Hepatitis B variation: a model of variation of molecular of variation of molecular epidemiology
                                                                       Australian Clinical Research Fellowship                                      University of Sydney
                                                                                                                           Hepatitis B variation: a model epidemiology          NSW
   980194   A/Pr Allison Jilbert      NHMRC Project Grants                                                                 Resolution of duck hepatitis
                                                                                                                                                    University of Adelaide
                                                                       Standard Project Grant Mechanisms of resolution of hepadnavirus infection B virus infection              SA
   981683   Prof Stephen Locarnini    NHMRC Project Grants                                                                 Examination of the key Melbourne in the
                                                                                                                                                    intermediate
                                                                       Standard Project Grant Characterisation of the hepatitis B virus minichromosome Health hepatitisVIC      B virus life cycle
   990988   Prof Stephen Locarnini    NHMRC Project Grants                                                                 Investigations into the significance of changes in hepatitis B virus treat
                                                                                                                                                     of hepatitis B virus       VIC
                                                                       Standard Project Grant Studies of polymerase/envelope protein variantsMelbourne Health resulting from antiviral selec
  8154   Dr Marc Le Mire                                     Medical                    Persistence of duck       Persistence of duck hepatitis B virusAdelaidetransient
                                                                                                                                            University of DNA in
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship hepatitis B virus DNA in transient & persistent infection SA & persistent infe
104892   A/Pr Allison Jilbert   NHMRC Project Grants                                                              Structure of hepadnaviral pre-genomic RNA.
                                                             Standard Project Grant Structure of hepadnaviral pre-genomic RNA. University of Adelaide                     SA
111710   Dr Elizabeth Grgacic   NHMRC Project Grants                                                               the ins and outs of hepatitis the enveloped hepatitis B virus. Researc
                                                                                                                                            Macfarlane Burnet Institute for Medical
                                                             Standard Project Grant Protein topogenesis and The assembly/disassembly ofB virus                            VIC
115030   Dr Patrick Bertolino   SRDC                                                                              Role of hepatocytes in University
                                                                                                                                             cell activation and tolerance
                                                             New Investigator Grant Role of hepatocytes in inducing primary CD8+ Ttolerance of Sydney                     NSW
142606   Prof Geoffrey McCaughanSRDC                                                                              Fibroblast Activation Protein and Liver
                                                                                                                                            Royal Prince Alfred HospitalNSW
                                                             Standard Project Grant The Role of Fibroblast Activation Protein in Chronic Liver Injury Injury
149501   A/Pr David Anderson    SRDC                                                    Polarized epithelia and How viruses get of hepatitis viruses
                                                                                                                                             out of the liver             VIC
                                                             Standard Project Grant with Research Fellowshipthe natural historyin and Macfarlane Burnet Institute for Medical Researc
149534   A/Pr David Anderson    SRDC                         NHMRC Research Fellowship                            natural history of hepatitis viruses Burnet Institute VIC
                                                                                                                                            Macfarlane                     viruses
                                                                                        Polarized epithelia & the Polarized epithelia & the natural history of hepatitis for Medical Researc
158010   A/Pr Allison Jilbert   SRDC                                                                              Mutant strains infection  University that cause
                                                             Standard Project Grant Virulence determinants in hepadnavirusof hepatitis B virus of Adelaidedisease         SA
158011   A/Pr Allison Jilbert   SRDC                                                                              Treatments for hepatitishepatitis infectioninfection. SA
                                                                                                                                              B virus B virus
                                                             Standard Project Grant Combination antiviral and immune therapies for University of Adelaide
164815   Dr Kaye Stenvers       SRDC                                                                              TGF-beta receptor typeLudwig Institute Modulation VIC growth activity
                                                                                                                                             III liver growth: for Cancer of TGF-beta
                                                             Standard Project Grant TGF-beta receptor type III in normal and malignant in normal and malignantResearch     liver
201700   Dr Joseph Sasadeusz SRDC                                                                                 co-infection.             Melbourne Health
                                                             Standard Project Grant Studies of HIV and HBV Studies of HIV and HBV co-infection.                           VIC
209196   Mr Theo Gouskos        SRDC                                                    Restoration               Restoration of HBV development of compensatory VIC
                                                                                                                                            University Melbourne           mutations in the vir
                                                             Dora Lush Biomedical Scholarship of HBV replication fitness by the replication fitness by the development of compens
219282   Prof Geoffrey Farrell  SRDC                                                    Centre for Clinical Research Excellence to improve outcomes in chronic liveroutcomes in chron
                                                             Centre of Clinical Excellence                                                  University of Sydney
                                                                                                                  Centre for Clinical Research Excellence to improveNSW      disease
237056   Miss Patricia Vietheer SRDC                                                    Development of recombinant hepatitis of virus particleshepatitis B virus particles as a of hepatitis
                                                             Dora Lush Biomedical Scholarship                                               Monash University
                                                                                                                  Development B recombinant as a platform for the VIC      delivery platform fo
253766   Prof Jacob George      SRDC                                                                              NASH pathogenesis in University of Sydney
                                                                                                                                            man                           NSW
                                                             Standard Project Grant Molecular and cellular pathogenesis of nonalcoholic steatohepatitis: Insights from human studie
262068   Dr Hani Tawk                                        Primary                    Hepatitis                  liver disease in familysUniversity of Sydney
                                                                                                                                             from disease in familys from different ethnic c
                                NHMRC Postgraduate Scholarships Health Care Scholarship B:prevention ofHepatitis B:prevention of liverdifferent ethnic communities        NSW
284420   A/Pr Hans Netter       CARG                         Development Grant                                      hepatitis B virus like particles asdelivery of delivery platform
                                                                                                                                            Monash a vaccine              VIC
                                                                                        Development of chimericMulti-component vaccine for theUniversity HIV-1 antigens for multip
295611                                                       Medical                    Studies on the natural history of e antigen negativeVincent'shepatitis B
         Dr Alexander ThompsonNHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                             St chronic Health
                                                                                                                  Studies on the natural history of e antigen negative VIC chronic hepatitis B
334269   Dr Christopher DesmondCARG                                                     Immunopathogenesis of Immunopathogenesis of Hep B virus infection
                                                             Medical Postgraduate Research Scholarship            Hep B virus infection Monash University                 VIC
344806   Dr David Iser                                       Medical                    Pathogensis and ntaural Pathogensis and ntaural history of liver HIV/HBVin the setting of HIV/HB
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                           in Vincent's of disease coinfection
                                                                                                                   history of liver disease St the settingHealth          VIC
382911   Dr Benjamin Cowie                                   Public                     The seroprevalence, molecular characterisation Melbourne Health
                                NHMRC Postgraduate ScholarshipsHealth Postgraduate Scholarship                                               & mathematical modelling mathematical mode
                                                                                                                                                                          VIC
                                                                                                                  The seroprevalence, molecular characterisation & of hepatitis B virus in
396700   Dr Nicholas Wood       NHMRC Project Grants                                                              Hepatitis B immunity in Indigenous and "atreceived NSW
                                                                                                                                             risk" children who risk" children
                                                                                                                                                                           hepatitis
                                                             New Investigator Grant Hepatitis B virus immunity in Indigenous and "at The Children's Hospital at WestmeadB vaccinat
401526   Prof ROBERT TINDLE NHMRC Project Grants                                                                  HBsAg as generic vaccine vector Queensland QLD
                                                                                                                                            University of
                                                             Standard Project Grant Development of Hepatitis B surfaceaantigen as a generic vector for the delivery of foreign CTL e
433900   A/Pr David Anderson                                 NHMRC Research Fellowship
                                Established Career Fellowships                                                    Uncoupled Research Fellowship Burnet Institute for Medical Researc
                                                                                        Uncoupled Research Fellowship                       Macfarlane                    VIC
433914   Dr Elizabeth Grgacic   NHMRC Project Grants                                                              Identification of HBV fusion
                                                                                                                                            Macfarlane Burnet Institute for Medical Researc
                                                             Standard Project Grant A new insight into hepatitis B infection:the HBV fusion peptide                       VIC
453505   A/Pr Allison Jilbert   NHMRC Project Grants                                                              Resolution infections University of infections
                                                             Standard Project Grant Resolution of acute hepatitis B virusof acute hepatitis B virus Adelaide              SA
453506   A/Pr Allison Jilbert   NHMRC Project Grants                                                              Immune therapies for chronic
                                                                                                                                            University of Adelaide
                                                             Standard Project Grant Immune therapies for chronic hepatitis B virus infectionhepatitis B virus infection   SA
453507   A/Pr Allison Jilbert   NHMRC Project Grants                                                              Clonal proliferation of hepatocytes disease in chronic B virus B virus i
                                                                                                                                            University in chronic         SA
                                                             Standard Project Grant Clonal proliferation of hepatocytes and progression of liverof Adelaidehepatitishepatitis infection
455355   Prof Gregory Dore                                   Practitioner Fellowship Practitioner Fellowship Practitioner Fellowship University of New South Wales
                                Established Career Fellowships                                                                                                            NSW
468100   Prof Sharon Lewin                                   Practitioner Fellowship Practitioner Fellowship Practitioner Fellowship Monash University
                                Established Career Fellowships                                                                                                            VIC
491017   Dr Ashley Mansell      NHMRC Project Grants                                                              Immunomodulation of Inflammatory Signaling B e Antigen (HBeAg)
                                                                                                                                             signaling by Hepatitis Pathways
                                                             Standard Project Grant Suppression of Immune Toll-like receptor (TLR) Monash University                      VIC
502028   Dr Catherine Croagh                                 Medical                    The role of Hepatitis      Antigen status in the natural history Melbourne determining outcomes
                                                                                                                                            Hepatitis B E Antigen in      VIC
                                NHMRC Postgraduate Scholarships Postgraduate Research Scholarship B E The significance of the University of and therapeutic outcomes of chron
508950   Prof David Jackson     CARG                         NHMRC Research Fellowship                            Uncoupled Research Fellowship of Melbourne
                                                                                        Uncoupled Research Fellowship                       University                    VIC
510104   Prof Lisa Maher        NHMRC Project Grants                                                              Hepatitis B Acceptability and Vaccine Incentive Wales Users
                                                                                                                                            University of New Injecting Drug
                                                             Standard Project Grant Randomised Controlled Trial of Hepatitis B Vaccine Completion in South Trial (HAVIT)  NSW
513896   Prof George Yeoh       NHMRC Project Grants                                                              How do liver stem cells University develop intoAustralia progenitor cells
                                                                                                                                             grow and of Western of liver WA
                                                             Standard Project Grant Mechanisms underlying growth, lineage commitment and differentiationfunctional liver cells?
513961   Dr Aibin Zhang                                      Australia - China Exchange Fellowship in growth,TNF-á and liver progenitor cells of Western Australia
                                International (Exchange) Early Career Fellowships       Role of TNF-á                                       University                    WA
                                                                                                                   lineage commitment and differentiation of liver progenitor cells
 520671   Dr Scott Patterson                                   Medical                   Clinical studies of novel antiviral therapies in advanced chronicB.
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                        University of Melbourne       VIC
                                                                                                                   New therapies for advanced hepatitis hepatitis B virus infection.
 521807   Dr Michelle Giles                                    Peter Doherty (Biomedical) ECF
                                   Early Career Fellowships (Australia)                                            Hepatitis B infection and impact on
                                                                                                                                            Alfred Hospital
                                                                                         Immunological changes during pregnancy and thepregnancy viral hepatitis infectionVIC
 546249   Dr Jennifer Audsley                                  Australian Clinical Research ECF implications and outcomes of anti hepatitis B virus (HBV) treatment in virus (HBV) tre
                                   Early Career Fellowships (Australia)                  Long-term                                          and outcomes of anti          VIC
                                                                                                                   Long-term implications Monash University hepatitis B HIV-HBV co-in
 568885   Prof John Kaldor                                     Centre of Clinical Research Excellence
                                   Centres for Research Excellence                                                 Centre for Clinical Research Excellence South Wales and bloodbor
                                                                                                                                            University of Sexually transmitted
                                                                                                                                                                          NSW
                                                                                         Centre for Clinical Research Excellence in Aboriginal Health: Newin Aboriginal Health: Sexually
 603756   Ms Rebecca Winter                                    Public                    Examining drug-related morbidity and mortality and sevice and mortality andfor Medical Researc
                                   NHMRC Postgraduate ScholarshipsHealth Postgraduate Scholarship                                            morbidity Burnet Institute sevice utilisation am
                                                                                                                   Examining drug-relatedMacfarlaneutilisation amongVIC    ex-prisoners
 630732   Dr Anna Olsen                                        Australian Training ECF for AboriginalA study of Hepatitis B knowledge, Research and New South Wales care among Au
                                   Early Career Fellowships (Australia)                                            A study of hepatitis B knowledge, treatment and health
                                                                                                                                            University                    NSW
                                                                                         Liver spots: and Torres Strait Islander Health treatment of health care among Indigenous Ind
 637350   Dr Marc Pellegrini                                   Clinical CDF
                                   Career Development Fellowships                                                   host genes and signalling forand Elizapromote immune clearance of
                                                                                                                                            Walter chronic Hall Institute
                                                                                         Trageted manipulation ofIndentifying new treatmentspathways to viral diseases    VIC
1004847   A/Pr Allison Jilbert     NHMRC Project Grants                                                            Hepatitis B Virus Covalently Closed Circular DNA SA
                                                               Standard Project Grant Hepatitis B Virus Covalently Closed Circular DNA      University of Adelaide
1006592   Dr Marc Pellegrini       NHMRC Project Grants                                                            Understanding the immune mediated pathology: an chronic and man
                                                                                                                                             factors that limit clearance VIC
                                                                                                                                                                          of
                                                               New Investigator Grant Chronic active viral persistence versus host hostWalter and Eliza Hall Institute analysis viruses
1011024   Prof Stephen Locarnini   NHMRC Project Grants                                                            Can Hepatitis B therapy enhance the progression SIGNIFICANCE OF T
                                                               Standard Project Grant ANTIVIRAL DRUG RESISTANT HBV: PATHOGENIC AND Health                                 VIC
                                                                                                                                            Melbourne ONCOGENIC to Liver Cancer?
1016351   Prof Andrew Lloyd        NHMRC Partnerships                                    Prevention                Prevention and treatment prisonersNew amongstNSW
                                                                                                                                            University of
                                                               Partnership Projects for Better Healthand treatment of viral hepatitis amongstof viral hepatitisSouth Wales prisoners
1017465   Mr Jesse Toe                                                                   Clearing                  Clearing chronic infectious diseases – effector function
                                                               Dora Lush Biomedical Scholarship chronic infectious diseases – enhancing host immune enhancing host immune effecto
                                   NHMRC Postgraduate Scholarships                                                                                                        VIC
                                                                                                                                            Walter and Eliza Hall Institute
1017784   Dr Uma Devi                                          Public                    Hepatitis B Virus         HBV drug Impact on and vaccine of Melbourne
                                                                                                                                            University escape
                                   NHMRC Postgraduate ScholarshipsHealth Postgraduate Scholarship Drug Resistance: resistance the Immunisation Program VIC
1024406   Prof Sharon Lewin        NHMRC Project Grants                                                            HIV-HBV co-infection Monash University
                                                               Standard Project Grant Liver disease in HIV-HBV co-infection                                               VIC
1034029   A/Pr Michael Kotiw       NHMRC Project Grants                                                            Development of a novel recombinant like particles expressing T and o
                                                                                                                                            University of Southern Queensland
                                                                                                                                                                          QLD
                                                               Standard Project Grant Construction and immunogenic evaluation of Hepatitis B virus vaccine for the dual prevention B
1038356   Dr Jane Davies                                       Medical                   Hepatitis B in the Top The the Northern and Disease Burden of Health of B Infection in the N
                                                                                                                                            Menzies School HepatitisNT
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship End of EpidemiologyTerritory: epidemiology, burden Research and healthdisease
1039019   Dr Roslyn Vongsuvanh                                 Medical                   Studies on the pathogenesis andon thediagnosis of hepatocellular carcinoma
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship                                        University of Sydney
                                                                                                                   Studies early pathogenesis and early diagnosis ofNSW    hepatocellular carc
1039055   Dr Kasha Singh                                       Medical                   The role of stellate      Dissecting mechanisms of progression progression in HIV-Hepatitis B
                                                                                                                                            Monash University             VIC
                                   NHMRC Postgraduate Scholarships Postgraduate Research Scholarship cells in fibrosis and liver disease liver disease in HIV-Hepatitis B co-infection
1039597   Prof Paul Hertzog        NHMRC Development Grants    Development Grant                                   Development of new antivirals. University
                                                                                         Development of new antivirals.                     Monash                        VIC
App    Start
             1996    1997    1998     1999     2000     2001      2002   2003   2004   2005   2006   2007   2008   2009
Year   Year
1995   1996 $49,572 $38,649 $22,443 $43,633 $55,709
1997   1998                $142,130 $162,752 $141,476
1997   1998                 $51,976 $59,237 $52,065
1998   1999                          $95,564 $83,716    $95,594
1999   2000   $26,889    $27,255
1999   2000   $51,278    $54,588
1999   2000   $62,501    $65,854 $69,530
1999   2000   $49,416    $52,588 $57,658
2000   2001              $65,285 $65,621     $65,621
2000   2001              $70,285 $70,621     $70,621 $70,621 $76,621
2000   2001              $66,366 $95,000     $99,250 $116,250 $118,500 $120,500
2000   2001             $125,380 $125,828   $125,828
2000   2001              $75,380 $75,828     $75,828
2000   2001             $120,285 $120,621   $120,621
2001   2002                       $65,330    $70,440
2001   2002                       $19,214    $19,659 $16,050
2001   2003                                 $400,000 $400,000 $400,000 $400,000   $400,000
2002   2003                                  $19,659 $20,484 $20,837                 $627
2002   2003                                 $107,750 $107,750
2002   2003                                  $19,659 $20,484 $22,496     $2,171      $735
2003   2004                                           $34,875 $104,625
2003   2004                                           $29,489 $30,014 $30,600      $15,754
2004   2006                                                         $1 $30,600     $31,422    $32,003    $16,359
2004   2005                                                    $30,014 $30,600     $31,422    $16,042
2005   2006                                                             $30,600    $31,422    $16,042
2005   2006                                                            $164,100    $49,663
2005   2006                                                            $143,500   $146,556   $149,586
2006   2007                                                                       $119,000   $121,500   $123,750
2006   2007                                                                        $94,100    $95,993    $98,117
2006   2007                                                                       $122,325   $119,618   $122,242
2006   2007                                                                       $117,225   $119,618   $122,242
2006   2007                                                                       $136,625   $140,446   $143,487
2006   2007                                                                                  $163,275    $84,175
2007   2008                                                                                   $70,625    $72,125
2007   2008                                                                                  $176,985   $180,950
2007   2008                                                                                   $32,003    $32,628
2007   2008                                                                                  $150,250   $153,250
2007   2008                                                                                  $194,860   $183,453
2007   2008                                                                                  $174,800   $178,571
2007   2008                                                                                  $107,550   $121,039
2007   2008                                                                                              $32,003    $32,628
2008   2009                                                                                                         $86,250
2008   2009                                                                                                         $53,438
2008   2009                                                                                                        $500,000
2009   2010
2009   2010
2009   2010
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2010   2011
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012
2011   2012

              Expenditure $523,050 $818,860 $765,251 $1,194,936 $816,003 $803,108 $952,671 $1,296,876 $1,913,199 $2,304,704
               # of grants   8        11       10        12        9        9        9         14         18         18
                                                     Broad Research         Field Of        Research Research Research Research
2010   2011   2012   2013   2014   2015   Total
                                                            Area           Research           KW 1      KW 2    KW 3     KW 4
                                          $210,005                      Epidemiology
                                                     Clinical Medicine and Science                                     TRACING
                                                                                           HEPATITIS BVARIANTSCONTACT VIRULENCE
                                          $446,359   Basic Science      Medical Virology              RESOLUTION OF INFECT
                                                                                           HEPADNAVIRUSES              AGE-RELATED EFFEC
                                                                                                              HEPATOCYTES
                                          $163,278   Basic Science      Medical Virology               VIRUS  CHROMATIN
                                                                                           HEPATITIS BMINICHROMOSOME NUCLEOSOMES
                                          $274,875   Basic Science      Medical Virology               VIRUS  VIRAL    HEPATITIS B VACCINE
                                                                                           HEPATITIS BPOLYMERASE ENVELOPE PROTE
                                    $54,144   Basic Science      Medical Virology HEPADNAVIRIS                  OUTCOME OF AMPLIFICATION
                                                                                                   VIRAL PERSISTENCEPCRINFECTION
                                  $105,866    Basic Science      Medical Virology Encapsidation                 Pre-genomic Reverse Transcription
                                                                                                   Hepadnavirus replicationRNA packaging
                                  $197,885    Basic Science                                        viral therapy protein
                                                                                                                viral hepatitis B virus
                                                                 Medical Virology targets for antiviralenvelopeof fusionassembly and topogenes
                                  $159,663    Basic Science                       CD8 T lymphocytesLiver and hepatocytes tolerance
                                                                 Immunology not elsewhere classified            autoimmunity
                                  $196,528    Basic Science      Hepatology                        Hepatic stellate cells tissue remodelling and
                                                                                                                Pathogenesis of
                                                                                  Cell surface peptidases and gelatinases chronic hepatitis, fe
                                  $358,770    Basic Science                                        Polarized Transcytosis iral pathogenesis
                                                                 Medical Virology Chronic viral infection epithelia         V
                                  $615,866    Basic Science      Not Allocated    N/A
                                  $377,037    Basic Science                                         variants to Cytopathic Hepatitis
                                                                                                                cause disease
                                                                 Medical Virology Ability of viral Altered viral phenotypevariants B virus infectio
                                  $227,037    Basic Science                                        Antiviral DNA
                                                                 Medical Virology Prime-boost protocols therapy vaccination Hepadnavirus infection
                                  $361,528    Basic Science                        Cell Biology not elsewhere III receptor
                                                                                                   TGF mice hepatocarcinogenesis
                                                                 Biochemistry andCre/lox transgenic beta typeclassified     hepatocyte
                                  $135,770                       Infectious Diseases
                                              Clinical Medicine and Science                        Hepatitis B Human
                                                                                                                virus       Therapeutics
                                                                                  Antiviral Resistance Mutations Immunodeficiency Virus
                                    $54,923   Basic Science      Medical Virology hepatitis        lamivudine replication fitness
                                 $2,000,000                      GastroenterologyCirrhosis
                                              Clinical Medicine and Science        and Hepatology  Hepatitis Liver Cancer   Nutrition
                                    $61,607   Basic Science                                        Hepatitis C Modified Platform delivery
                                                                                                                 virus
                                                                 Medical Virology Hepatitis B virus envelope protein virus-like particles of fore
                                  $215,500                       GastroenterologyGastroenterology
                                              Clinical Medicine and Science        and Hepatology               L
                                                                                                   Hepatocytes iver         Nonalcoholic steatohepa
                                    $65,546   Public Health      Family Care                       Hepatitis                knowledge and
                                                                                  Antenatal screening B health services utilisation beliefs
                                  $139,500                       Medical Virology HIV/AIDS
                                              Clinical Medicine and Science                                                 Viral immunity
                                                                                                   Hepatitis B Vaccine Development
                                  $105,857    Basic Science                                        Hepatitis B               analogues
                                                                 Medical Virology Drug resistant mutations Nucleoside Precore mutation
                                  $110,385                       Cellular Immunology
                                              Clinical Medicine and Science       Hepatitis B Viral immunity    immunopathology
                                  $108,078    Basic Science      Medical Virology HAART            HIV          Hepatitis fibrosis
                                    $78,064   Public Health      Epidemiology                                   Virus       Seroprevalence
                                                                                  Biostatistics Hepatitis B Mathematical model
                                  $213,763                       Infectious Diseases
                                              Clinical Medicine and Science                                     ImmunisationPopulation health
                                                                                  EpidemiologyHealth Policy and Sevices evaluation
                                  $439,643    Basic Science                       hepatitis B immunotherapy
                                                                 Cellular Immunology                                        virology
                                                                                                                vaccine development
$126,101   $128,371   $130,553    $749,275                       Biotechnology not elsewhere classified Virology procedures
                                              Clinical Medicine and Science                         Hepatitis; Immunity infection
                                                                                  Antiviral, ViralDiagnostic tests and toVaccine development, D
                                  $288,210    Basic Science                                        viral fusion
                                                                 Medical Virology viral entry mechanisms virology of hepatitis B virus
                                  $364,185    Basic Science                       Covalently closed circular DNA effects
                                                                 Infectious Diseases                            HepatocyteHistologicalproliferation
                                                                                                   Cytokine mediated         death and techniques
                                  $359,085                       Hepatology
                                              Clinical Medicine and Science       Antiviral                     Humoral and cellular immunity
                                                                                                   Duck hepatitis B virus Prime-boost vaccination
                                  $420,558                       Hepatology
                                              Clinical Medicine and Science                        Hepatocytes              Inverse
                                                                                  Hepatocyte proliferation In situ hybridization nested PCR
 $85,774    $87,318               $420,542                       Infectious Diseases
                                              Clinical Medicine and Science                        chronic hepatitis B; C heapatitis with hepatitis
                                                                                                                clinical HIV
                                                                                  acute hepatitis, chronic hepatitis care of personC; hepatitis B
 $73,495    $74,818    $76,090    $367,153    Clinical Medicine and Science
                                                                 Infectious Diseases
                                                                                  Anti-viral immunity           Chronic     HIV-AIDS,
                                                                                                   Anti-viral therapy hepatitis B Hepatitis B
$184,386                          $542,321    Basic Science                       Hepatitis B Immunosuppression Signaling pathways
                                                                 Infectious Diseases                            Innate Immunity
 $23,712                            $88,343                      Gastroenterologyhepatic fibrosis
                                              Clinical Medicine and Science        and Hepatology  hepatitis B liver cancer
$156,161   $158,972   $142,949    $761,582    Clinical Medicine and Science not elsewhere classified by hepatitis
                                                                 Immunology                        caused       diseases,infection control,chronic d
                                                                                                                            hepatitis,influenza,repro
                                                                                  Vaccine development,antigen presentation,viral
 $85,042                          $463,355    Public Health                        Health Services not elsewhere classified prevention
                                                                 Public Health andacceptability hepatitis B injecting drug use
$181,962                          $535,333    Basic Science      Hepatology                        inflammatory cytokinesliver commitment
                                                                                                                liver cell
                                                                                  hepatocytes and cholangiocytes lineageprogenitor cells
                                  $228,589                       GastroenterologyHepatitis B Hepatitis C Liver progenitor cells
                                              Clinical Medicine and Science                                                 Stem cells
                                                                      $64,631                      Hepatology
                                                                                Clinical Medicine and Science        antiviral                               prophylaxis
                                                                                                                                    hepatitis B liver transplantation
  $87,508    $89,083    $90,598                                     $353,439    Clinical Medicine and Science
                                                                                                   Infectious Diseases              Perinatal transmission
                                                                                                                                                Viral hepatitis
                                                                                                                     Immunological changes in pregnancy
  $72,508    $73,813    $75,068    $18,767                          $293,594    Clinical Medicine and Science
                                                                                                   Infectious Diseases              drug resistance
                                                                                                                     HIV-HBV co-infection                    hepatotoxicity
                                                                                                                                                hepatic fibrosis
 $500,000   $509,000   $517,653   $517,653                         $2,544,306                      Clinical Sciences Aboriginal health
                                                                                Clinical Medicine and Science                       Sexually transmitted infections
                                                                                                                      not elsewhere classified Viral hepatitis
  $24,750    $25,110    $26,479                                       $76,339   Public Health                         Health Services not elsewhere classified
                                                                                                                                    drug                     risk behaviour
                                                                                                   Public Health andPrison populationsuse health servcie utilisation
  $72,508    $73,813    $75,068    $75,068                          $296,457    Public Health                        Aboriginal Islander Health viruses Health services access
                                                                                                                                    Blood borne Health promotion
                                                                                                   Aboriginal and Torres Strait and Torres Straight Islander health
  $96,040    $97,769    $99,431    $99,431                          $392,670    Clinical Medicine and Science
                                                                                                   Infectious Diseases              HBV
                                                                                                                     Chronic viral infections HCV            Herpes viruses
             $99,263   $100,951   $100,951                          $301,164                       Medical Virology hepatitis B virus hepatitis B virus viral replication
                                                                                Clinical Medicine and Science                       duck        hepatocytes
            $137,161   $139,493   $139,493                          $416,147    Basic Science                                       human       chronic infection
                                                                                                                                                             T cells
                                                                                                   Medical Virology virus pathogenesis immunodeficiency virus (HIV)
            $166,852   $169,689   $169,689                          $506,230    Clinical Medicine and Science
                                                                                                   Gastroenterologyhepatocellular carcinomadrug resistance disease
                                                                                                                      and Hepatologyhepatitis B virus        liver
            $356,278   $369,789   $369,789                         $1,095,855                      Health            hepatitis C infection B infection prevention
                                                                                Health Services Researchand Community Services      hepatitis prison population
             $25,110    $25,979    $26,479                            $77,567   Basic Science                                       chronic infection
                                                                                                                                                therapeutic
                                                                                                   Medical Virology human immunodeficiency virus (HIV)target
             $36,286    $37,579    $38,079                          $111,945                       Medical Virology hepatitis B infection
                                                                                Clinical Medicine and Science                                   vaccination failure
                                                                                                                                    drug resistance
                       $121,425   $216,687   $191,898   $163,920    $693,930    Clinical Medicine and Science
                                                                                                   Medical Virology hepatitis B infection immunodeficiency virus (HIV)
                                                                                                                                    human       liver diseaseliver fibrosis
                       $163,966   $163,966   $163,966               $491,897    Clinical Medicine and Science
                                                                                                   Medical Molecular Engineeringotitis mediaStreptococcus pneumoniae
                                                                                                                                     of                      hepatitis
                                                                                                                     Aboriginal child Nucleic Acids and Proteins B virus
                        $37,618    $37,618    $38,118               $113,353    Public Health      Epidemiology                     hepatitis B infection molecular epidemiology
                                                                                                                     hepatitis B virus          epidemiology
                                   $37,618    $38,118                 $75,735                      Cancer Diagnosis
                                                                                Clinical Medicine and Science                       hepatocellular cancer
                                                                                                                     hepatocellular carcinomahepatoma liver cancer
                        $28,213    $37,618    $38,118     $9,404    $113,353    Basic Science                                       human       fibrosis     stellate cells
                                                                                                   Innate Immunity hepatitis B infection immunodeficiency virus (HIV)
                       $211,209   $211,209                          $422,418    Basic Science                        interferon-alpha (IFN-alpha)
                                                                                                                                    hepatitis hepatitis innate immunity
                                                                                                   Immunology not elsewhere classified B infection C infection

$1,769,947 $2,139,017 $2,639,800 $2,260,115 $470,218    $173,324 $21,507,038
    14         16         20         16        5           2
Research Health   Health   Health   Health   Health              Media
                                                      Status
  KW 5     KW 1   KW 2     KW 3     KW 4     KW 5               Summary
ANALYSTS                                              Closed             END
                                                               Media Summary not available
CYTOKINES                                             Closed             END
                                                               Media Summary not available
TRANSCRIPTION                                         Closed             END
                                                               Media Summary not available
ANTIVIRALS                                            Closed             END
                                                               Media Summary not available
R AMPLIFICATION                                                                       Closed                      END
                                                                                                   Media Summary not available
                        Design       Liver disease
                                                 Persistent hepatitis B virus infection
           Viral recombinationof antiviral therapies          Viral recombination Closed                          END
                                                                                                   Title: Structure of hepadnaviral pre-genomic RNA. We aim to study the replication strategy of human hepa
                                     hepatitis B targets for antiviral therapy of hepatitis B infectionestimated END million people worldwide, and 250,000 in Australia, are chronically infected with the hepa
                        chronic viral infection virus infection                       Closed       An             350
                        Hepatocarcinomas
           transgenic mice                       liver autoimmune diseases
                                                              transplantation
                                     autoimmune and viral Hepatitis                   Closed                      END
                                                                                                   It is well known that tolerance to liver allografts is more readily achieved than to other organ grafts, even ac
                         extracellular matrix Hepatitis B Hepatitis C hepatocellular carcinoma
 ue remodelling andChronic hepatitis Cirrhosis                                        Closed                      END
                                                                                                   Chronic liver diseases, particularly those caused by Hepatitis B virus and Hepatitis C virus infection, are m
           Virus release             Chronic     Enterically Viral hepatitis
                                                                           hepatitis Closed
                        Chronic hepatitis B hepatitis C transmitted Viral infections                              END
                                                                                                   The viruses causing hepatitis in man must cross specialised cell layers in the body to reach the liver, and m
                                                                                      Closed                      END
                                                                                                   Media Summary not available
                        Extrahepatic disease Viral hepatitis
patitis B virus infection            Liver disease                                    Closed                      END
                                                                                                   The human hepatitis B virus (HBV) is a member of the hepadnavirus family that includes a number of othe
                        Antiviral therapy
           Immune therapy                        Hepatitis
                                     Chronic liver diseaseB virus infection           Closed                      END
                                                                                                   Hepatitis B virus (HBV) causes acute and persistent (chronic) infection with varying degrees of liver damag
patocyte                                         liver fibrosis
                        hepatitis hepatocarcinogenesis metastasis                     Closed                      END
                                                                                                   The transforming growth factor-beta (TGF-beta) family is a group of multifunctional growth factors which re
erapeutics              AIDS                     Cirrhosis Hepatocellular carcinoma
                                     Acute Hepatitis                                  Closed                      END
                                                                          Liver transplantation There are a number of patients throughout Victoria that are co-infected with both hepatitis B virus (HBV) an
                                                                                      Closed                      END
                                                                                                   Media Summary not available
           Osteoporosis                                                               Closed                      END
                                                                                                   This Centre will provide new information to improve clinical outcomes for people with chronic liver disease.
           Vaccine                                                                    Closed                      END
                                                                                                   Media Summary not available
                        Chronic      Chronic liver injury
nalcoholic steatohepatitis liver disease Hepatitis Hepatocellular injury Closed                                   steatohepatitis (NASH) is the commonest cause for liver disease in Australia. On liver biopsy
                                                                                                   Nonalcoholic END
           risk factors                                                               Closed                      END
                                                                                                   Media Summary not available
           Virus-like particle                                                        Closed       The small envelope protein of hepatitis B virus (HBsAg) can self-assemble into highly organised viruslike p
                                                                                                                  END
           Replication fitness                                                        Closed                      END
                                                                                                   Media Summary not available
                                                                                      Closed                      END
                                                                                                   Media Summary not available
                                                                                      Closed                      END
                                                                                                   Media Summary not available
           molecular virology                                                         Closed                      END
                                                                                                   Media Summary not available
                                                 carrier mothers
           Prevention Hepatitis B Hepatitis B Immune response Indigenous health       Closed                      END
                                                                                                   Hepatitis B virus (HBV) is transmitted by blood exposure or sexual contact and infection can result in chron
                        DNA          hepatitis B immunity-cellular
           virus-like particleand VLP Vaccinesurface antigen              vaccine vectors
                                                              immunotherapy           Closed                      END
                                                                                                   Many kinds of cancer and infections display unique proteins which the body's immune system can recognis
           vaccine technology                                                         Paying                      END
                                                                                                   I am a virologist exploiting basic and applied research on hepatitis viruses to develop biotechnology innova
 atitis B virus                      hepatitis B virus B virus
                                                 liver infection
                        chronic carriers of hepatitis cancer                          Closed                      END
                                                                                                   Three hundred and fifty million people worldwide and 250,000 in Australia are chronically infected with hep
                        Hepatocellular carcinoma
           Inverse nested PCR Liver disease                   Therapy for chronic infection
                                                                                      Closed
                                                 Resolution of hepatitis B virus infection                        END
                                                                                                   Though vaccination has had a major impact on the number of persons becoming infected, chronic infection
                        Antiviral therapy
                                     Chronic     Chronic liver infection
                                                              Immunotherapy           Closed                      END
           Recombinant fowlpoxviruses hepatitis B virus disease Vaccine development Hepatitis B virus (HBV) causes acute and chronic infection leading to severe liver damage in many patients
                        Chronic      Cirrhosis ofHepatocellular carcinoma
                                                  the liver
           Viral persistence hepatitis B virus infection Viral hepatitis              Closed       Infection with the hepatitis B virus (HBV) can lead to either acute resolving, or chronic HBV infection. Chron
                                                                          Viral-induced cancer/oncogenesis END
apatitis C; hepatitis B; HIV-AIDS; therapy                                            Paying                      END
                                                                                                   I am infectious disease physician undertaking research on natural history and therapeutic strategies in vira
           Immunology, Viral persistence                                              Paying                      END
                                                                                                   I am an infectious diseases physician and basic scientist interested in the immunopathogenesis of HIV and
                        Hepatitis Virus Infection
           Toll-like receptors B ImmunomodulationInflammation Sepsis                  Paying                      END
                                                                                                   Hepatitis B virus (HBV) infection is a major world-wide health problem, which the current treatment strategi
                                                                                      Paying                      END
                                                                                                   Hepatitis B can cause liver failure and cancer and affects between 90,000 and 160,000 people in Australia
patitis,influenza,reproduction, infectious                                            Paying                      END
                                                                                                   I am an immunologist with a background in virology and peptide chemistry and my work is therefore inter-d
                                                 liver        p           substance use
                                                                                      Paying                      END
           vaccinationhepatitis B immunisation diseaserevention of infectious disease This randomised trial will examine strategies to increase hepatitis B vaccination in drug users by comparing
                                                 viral hepatitis, HBV and HCV
           stem cells cell therapychronic liver disease                               Paying                      END
                                                                                                   Liver diseases associated with Hepatitis C, including liver failure and liver cancer, are now the leading indic
           Tissue regeneration                                                        Closed                      is a
                                                                                                   Liver diseaseENDserious health problem. Viral hepatitis, obesity and alcohol can result in end-stage liver d
         viral immunology                                                          Closed                    END
                                                                                              Hepatitis C virus (HCV) infects 3% of the world's population and causes an estimated 476,000 deaths per
                                                                                   Paying     Hepatitis B virus (HBV) can cause long term health problems particularly affecting the liver and can be pas
                                                                                                             END
patotoxicity                                                                       Paying                    END
                                                                                              Chronic hepatitis B (HBV) infection may cause serious liver disease in some people, including liver failure
                                                                                   Paying                    END
                                                                                              This proposed new CCRE will bring together the leading Australian institution dedicated to clinical research
         viral hepatitis                                                           Paying                    is a
                                                                                              Hepatitis C isENDleading cause of liver transplants, and affects an estimated 180 million people worldwide
alth services access                                                               Paying     Despite Australia’s successful hepatitis B vaccination campaign for infants many Australians are still vulne
                                                                                                             END
rpes viruses                                                                       Paying                     B and
                                                                                              HIV, HepatitisEND Hepatitis C are major health issues, especially to indigenous people. Finding effective
                      hepatitis B infection antiviral therapy
         viral persistence        liver disease                       cell proliferation
                                                          paracetamol toxicity Paying                        END
                                                                                              Worldwide >360 million people have chronic hepatitis B virus (HBV) infection that imparts a 25% lifetime ri
                                  human       virus pathogenesis (HIV)
                                                          hepatitis hepatitis Paying
         cytokines chronic infection immunodeficiency virus B infection C virus                              END
                                                                                              Our robust ability to mount an immune response and clear infections is tempered by the possibility of prom
 r disease                        liver cancerhepatocellular carcinoma
                      hepatitis B infection                                        Paying                    END
                                                                                              We aim to investigate the consequences of long-term therapy for hepatitis B on liver cancer progression. W
                      hepatitis C infection B infection drug use
         health services research hepatitis injecting liver disease                Paying                    END
                                                                                              Hepatitis B and C infection rates remain very high in some Australian populations, notably prisoners. As th
                                  human       immune modulation (HIV)
                                                          hepatitis hepatitis Paying
                      chronic infection immunodeficiency virus B infection C virus                           END
                                                                                              Chronic infections produced by pathogens such as HIV, overwhelm our immune system leading to an exha
                      hepatitis B infection immunisation
                                  drug resistance                                  Paying     “Antiviral drug-associated vaccine escape mutants” have the potential to jeopardize the hepatitis B immuni
                                                                                                             END
         inflammation immunology                                                   Accepted   Morbidity andENDmortality secondary to liver disease is greatly increased in people co-infected with HIV and H
         vaccine development                                                       Paying                    END
                                                                                              Australian Indigenous children suffer abormally high levels of middle ear infections (term otitis media). In m
                      communication skills burden of disease
         health literacy          health education                                 Paying                    END
                                                                                              I am an Infectious Diseases doctor working with Hepatitis B in the Top End of the Northern Territory. I will p
                      cancer      cancer      liver
         cancer detection screening genetics fibrosis                 hepatitis Accepted
                                                          hepatitis C infection B infection                  END
                                                                                              Hepatocellular carcinoma (HCC) is the most common primary liver cancer and worldwide is the third and fi
         hepatitis                                                                 Paying                    END
                                                                                              Liver related mortality is the commonest cause of non-AIDS death in HIV infected individuals on treatment.
         immune response                                                           Accepted                  END
                                                                                              Despite recent advances in therapeutic options, chronic viral infections, including infection with hepatitis C
NHMRC FUNDED RESEARCH INTO HEPATITIS C ISSUES 2000-2012
Grant Types: All "Hepatitis C",
Keywords: Hepatitis (reviewed for viral Hepatitis), HEP, Hepatitis C, HEP C, HCV
Report Run: 3 July 08/19 Mar 09/10 Mar 10/28 Feb 11/7 May 12
Sources: Extracted from NHMRC Databases -RGMS/ RMIS/GMS as at May 12
Summary Notes
1. This dataset contains the details of all NHMRC funded research grants that have been identified as having a connection with the
disease area of Hepatitis C (Hep C) through search of the Chief Investigator provided keyword and titles contained in the NHMRC
research database. Relevance to the research area in question may be either immediate or be a longer term perceived benefit. This
dataset was current as at 7 May 12 but is subject to change over time.
Summary of Expenditure: Hepatitis C Research
      2000             $1,403,587 Actual Expenditure          26 grants
      2001             $2,009,494 Actual Expenditure          28 grants
      2002             $1,813,596 Actual Expenditure          24 grants
      2003             $1,730,463 Actual Expenditure          24 grants
      2004             $1,848,513 Actual Expenditure          22 grants
      2005             $3,445,377 Actual Expenditure          28 grants
      2006             $5,141,241 Actual Expenditure          32 grants
      2007             $5,926,971 Actual Expenditure          40 grants
      2008             $6,391,409 Actual Expenditure          43 grants
      2009           $10,502,599 Actual Expenditure           43 grants
      2010             $9,603,872 Actual Expenditure          42 grants
      2011             $8,827,015 Actual Expenditure          42 grants
      2012             $8,953,809 Forecast Expenditure        41 grants
     Total           $67,597,946 As at Dec 12
      2013            $7,344,357 Forward commitments          24 grants
      2014            $1,389,192 Forward commitments          12 grants
      2015              $269,387 Forward commitments          3 grants
      2016              $106,526 Forward commitments          1 grant
      Total          $76,707,408 Incl out years
2 . Forward commitments funding data for out-years (ie beyond 2012) is subject to change when new grants are awarded in subsequent years

 Grant Id       CIA Full Name                  CARG                    Grant Subtype      Scientific Title      Simplified Title      Admin Institutution
 956084   Prof Ian Anderson     CARG                      ANCARD Project Grant                                   Developing a HIV and HepC Risk Reduction Program for IDU in th
                                                                                                                                         Victorian Aboriginal Health Service
                                                                                       Developing a HIV and HepC Risk Reduction Program for IDU in the Melbourne Koori Com
 967448   Mr Ricardo Lareu                                Dora Lush                    Role of                   Role of novel apoptosis-associated Western Australia
                                NHMRC Postgraduate Scholarships Biomedical Scholarship novel apoptosis-associated gene in tumour         University of gene in tumour
 977157   Dr George Marinos                               Australian Clinical Research The immunopathogenesis ofimmunopathogenesis of chronic hepatitis c Walesinfection
                                Early Career ECFs (Australia)                           ECF                                              University of New
                                                                                                                 The chronic hepatitis c virus infection South virus
 981447   Prof Eric Gowans      NHMRC Project Grants      Standard Project Grant                                 Hepatitis C virus replication Children's Hospital, Brisbane
                                                                                       Molecular events of hepatitis C virus replication Royal
983604    Prof Jill COCKBURN SRDC                         Hepatitis C                                            An intervention to improve compliance with in penetration g/lines
                                                                                                                                         University of g/lines skin
                                                                                       An intervention to improve compliance with skin penetrationNewcastleTattooists, Beauty T
983608    Prof John Crofts      SRDC                      Hepatitis C                                            Peer counselling and Macfarlane Burnet needle for syringe exch
                                                                                                                                          testing
                                                                                       A pilot peer-based hepatitis Ctesting for Hepatitis C service at a Instituteand Medical Res
983610    Prof John Crofts      SRDC                      Hepatitis C                                            HCV education and Vietnamese IDUs
                                                                                                                                         Macfarlane ethnicity
                                                                                       Prevention of HCV infection amongst IDUs of Vietnamese Burnet Institute for Medical Res
983615    Dr Alex Wodak         SRDC                      Hepatitis C                                            Encouraging drug injectors who cannot stop drug use to
                                                                                                                                         University of New South Wales
                                                                                       A feasibility study of non-injecting routes of administration (NIROA) among IDUs shift to us
983618    A/Pr Gary Dowsett     SRDC                      Hepatitis C                                            Gay men, men who inject drugs in Melbourne's gay community
                                                                                                                                          and Hepatitis C prevention
                                                                                       Hepatitis C prevention among gay drug culture La Trobe University
983619    A/Pr Michael Dunne SRDC                         Hepatitis C                                            Quality of with chronic Queenslandinfection
                                                                                                                                           Hepatitis C University Hepatitis C_infectio
                                                                                       Quality of life among people living life among people living with chronicof Technology
983627    Prof Sandra Gifford   SRDC                      Hepatitis C                                            The health health needs of women living with Hepatitis C
                                                                                                                                         Deakin University
                                                                                       Identifying the social, personal and and well being of women living with Hepatitis C
983629    Prof Jeanette Ward    SRDC                      Hepatitis C                                              national study of hepatitis C in general practiceHealth of care
                                                                                                                                         Sydney South West Area
                                                                                       National surveys of GPsAand their patients about needs, outcomes and patternsServices -
983633    Prof Susan Kippax     SRDC                      Hepatitis C                                            IDU - Data collection. Transition to injecting
                                                                                                                                         University of New South rural youth
                                                                                       Risks for Hepatitis C: Transition to injecting drug use among urban and Wales
983641    A/Pr Wendy Loxley     SRDC                      Hepatitis C                                            Exploring testing injecting drug users tested for hep C and other
                                                                                                                                         Curtin University hepatitis and
                                                                                       Investigation of the process by which injecting drug users are forof Technology HIV/AIDS b
983654    Dr Greg Rumbold       SRDC                      Hepatitis C                                            A national survey of hepatitis CPointpracticesand An injecting of
                                                                                                                                         Turning risk Alcohol among overview
                                                                                       A national survey of hepatitis C risk practices among injecting drug users:Drug Centre drug
983657    Prof Susan Sawyer     SRDC                      Hepatitis C                                            Reducing transmissionMurdochin a peer education Institute
                                                                                                                                            of HCV Childrens young people
                                                                                       Reducing transmission of HCV in high risk young people -high-riskResearch strategy
990657    Prof Andrew Lloyd     CARG                      ANCARD Project Grant                                   natural history and determinants of viral clearance in primary hepa
                                                                                                                                         University of New South Wales
                                                                                       Modes of transmission, Transmission and clearance of HCV
991357    A/Pr Rohan JayasuriyaCARG                       ANCARD Project Grant                                   Study of Risk Behaviour Users for Wollongong of transmission
                                                                                                                                         University of Drug Users
                                                                                       Cohort Study of Risk Behaviour in Injecting Drugin Injectingtransmission for Hepatitis C o
991502    Prof Eric Gowans      NHMRC Project Grants      Standard Project Grant                                 Hepatitis C and dendritic cells
                                                                                                                                         Royal Children's Hospital, in HCV infection
                                                                                       Immunopathogenesis and immunotherapy associated with dendritic cells Brisbane
997468                                                    Medical                      Mechanisms of             Mechanisms of response and non-response Australia in chronic
                                                                                                                                           interferon-alpha therapy (IFN-a)
          Dr Gerard MacQuillan NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarshipresponse and non-response toUniversity of Western to interferon-alpha the
  459     Prof Sandra Gifford   NHMRC Project Grants      Standard Project Grant                                 A Ethnographic Study theSouth- East social Women Living with h
                                                                                                                                           of Helath and Asian Needs of HCV positiv
                                                                                       Bad Blood, Bad Livers: AnQualatative Study of Deakin University
 7087                                                     Australian Clinical Research INVESTIGATION OF THE NATURAL HISTORY OF COMMUNITY ACQUIHEP C IN A CO
          A/Pr Margaret Hellard Early Career ECFs (Australia)                           ECF                                              Monash University
                                                                                                                 INVESTIGATION OF THE NATURAL HISTORY OF COMMUNITY
 7443     Dr Charles Harvey                               Dora Lush
                                NHMRC Postgraduate Scholarships Biomedical Scholarship                           Correlation outcomes responsesof New South following immunoth
                                                                                                                                           following to outcomes Wales
                                                                                       Correlation of immune responses toof immune Universityimmunotherapy in chronic hepatit
 8130     Dr Anouk Dev                                    Medical                      Factors affecting         Factors affecting the course of hepatitis C in South-East Asian wo
                                                                                                                                         Monash University
                                NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship the course of hepatitis C in South-East Asian women
 8175     Dr Jeffrey Post                                 Medical                      Natural history of        Natural history of infection
                                                                                                                                         University of New South Wales
                                NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship primary hepatitis C virusprimary hepatitis C virus infection
102421    Prof Eric Gowans      NHMRC Project Grants      Standard Project Grant                                 A vaccine for hepatitis Macfarlane Burnet Institute for Medical Res
                                                                                                                                         C
                                                                                       A virus-like particle vaccine for hepatitis C virus. virus.
102481    Dr Jason Mackenzie NHMRC Project Grants         Standard Project Grant                                 Where and how the viruses roles of Australian encephalitis and de
                                                                                                                                         University of induced membranes
                                                                                       Flavivirus replication - biogenesis, ultrastructure andcausingQueensland
111701    Prof John Crofts      CARG                      ANCARD Project Grant                                   How do social networks of injecting drug users affect Medical Res
                                                                                                                                         Macfarlane Burnet of the hepatitis C virus
                                                                                       Injecting drug users: social networks and molecular epidemiology Institute for the spread o
136917    Prof Sandra Gifford   NHMRC Project Grants      Standard Project Grant                                 Investigating the health and well living of men living with
                                                                                                                                         Deakin University
                                                                                       Identifying the social, personal and health needs of men being with hepatitis C. hepatitis
142606                          NHMRC Project Grants
          Prof Geoffrey McCaughan                         Standard Project Grant                                 Fibroblast Activation Protein and Injury
                                                                                                                                         Royal Prince Alfred Hospital
                                                                                       The Role of Fibroblast Activation Protein in Chronic Liver Liver Injury
142607                          NHMRC Project Grants
          Prof Geoffrey McCaughan                         Standard Project Grant                                 Pathogenesis of hepatitis hepatitis C virus Hospital
                                                                                                                                         Royal Prince Alfred
                                                                                       Novel approaches to the pathogenesis of chronic C virus infection associated liver disease
145884                                                    Medical                      Cellular immunity         Cellular immunity in hepatitis C exposed uninfected injecting drug
                                                                                                                                         University of New South and transfused th
          Dr Anthony Freeman NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship in hepatitis C exposed uninfected injecting drug usersWales
149501    A/Pr David Anderson NHMRC Project Grants                                     Polarized Fellowship How viruses get in andMacfarlaneliver
                                                                                                                                           out of the Burnet Institute for Medical Res
                                                          Standard Project Grant with Research epithelia and the natural history of hepatitis viruses
149534                                                    NHMRC Research Fellowship
          A/Pr David Anderson Established Career Fellowships                                                     Polarized epithelia & the natural history of hepatitis viruses
                                                                                                                                         Macfarlane
                                                                                       Polarized epithelia & the natural history of hepatitis virusesBurnet Institute for Medical Res
156714                          NHMRC Project Grants
          Dr Pantelis Poumbourios                         Standard Project Grant                                 How does Hepatitis C Virus infect Institute of Medical Research
                                                                                                                                         St
                                                                                       Molecular Mechanisms of Hepatitis C Virus entry.Vincent'scells?
157128    Prof Susan Kippax     NHMRC Project Grants      Standard Project Grant                                 Blood awareness in Hepatitis C prevention education
                                                                                                                                         University of New prevention education and
                                                                                       An analysis of "blood awareness" for the purposes of Hepatitis C South Wales
165702   Dr Amany Zekry                                    Medical                      Immunopathogenesis and Differential Gene Expression of Hepatitis C Virus Post Liver Tra
                                NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                          University of Sydney
                                                                                                                  Immunopathogenesis and Differential Gene Expression of Hepatit
191805   Prof Eric Gowans       NHMRC Project Grants       Standard Project Grant                                 Hepatitis C culture andMacfarlane Burnet Institute for Medical Res
                                                                                                                                            control
                                                                                        The in vitro culture of hepatitis C virus and approaches to the control of replication
191820   Prof John Crofts                                  NHMRC Research Fellowship
                                Established Career Fellowships                                                    Uncoupled               Macfarlane
                                                                                        Uncoupled Research Fellowship Research Fellowship Burnet Institute for Medical Res
207817   Dr MICHAEL BEARD NHMRC Project Grants             New Investigator Grant                                 Oxidative Stress Hepatitis C Virus and its Role
                                                                                                                                          University of Adelaide
                                                                                        Induction of Reactive Oxygen Species byin HCV Related Liver Disease in Liver Pathogene
210109   A/Pr Julie Jonsson     NHMRC Project Grants       Standard Project Grant                                 of the Renin-Angiotensin the Renin-Angiotensin
                                                                                                                                          University in hepatic fibrosis.
                                                                                        Investigation of the role Investigation of the role ofSystem of Queensland System in liver fi
210232   A/Pr Hans Netter       NHMRC Project Grants       Standard Project Grant                                 Synthesis of virus-like particles carrying a response against quas
                                                                                                                                          Monash an immune
                                                                                        Development of a HBV-specific carrier matrix to induce University variety of foreign epitope
210356   Dr Ingrid Hickman                                 Dora Lush                    The role                  The role of obesity andUniversityin chronic hepatitis
                                                                                                                                            nutrition of Queensland
                                NHMRC Postgraduate Scholarships Biomedical Scholarship of obesity and nutrition in chronic hepatitis C and fatty liver diseaseC and fatty live
222887   Prof Andrew Lloyd      NHMRC Project Grants                                    The HITS study: modes HITS: a prospective cohort study of New South Wales in prisoner
                                                           Large Scale Clinical Trials Project Grant                                      University     determinants of C
                                                                                                                   of transmission, natural history and primary hepatitisoutcome from
222922   Dr Loren Brener                                   Public Health Postgraduate Scholarship workers and hepatitis C workers and hepatitisof New South Wales study of hea
                                NHMRC Postgraduate Scholarships                         Health care                                       University C of health care experiences
                                                                                                                  Health care positive clients: a study positive clients: a
229304   Prof Sandra Gifford    NHMRC Project Grants       Standard Project Grant                                 Discrimination, hepatitis Cto discrimination
                                                                                                                                          La in health care settings.
                                                                                        Discrimination or Discretion? Factors contributing Trobe University of people with hepatitis
234428   Mr Paul Myers                                     Public Health Postgraduate Scholarship
                                NHMRC Postgraduate Scholarships                                                   A cross-national longitudinal study of HCV risk practices homeless
                                                                                                                                           practices of Melbourne
                                                                                        A cross-national longitudinal study of HCV risk University and health outcomes in and healt
237056                                                     Dora Lush
         Miss Patricia Vietheer NHMRC Postgraduate Scholarships Biomedical Scholarship                            Development B virus particles University
                                                                                                                                          Monash as a platform particles as a of he
                                                                                        Development of recombinant hepatitisof recombinant hepatitis B virusfor the delivery platfo
254666   Prof George Yeoh       NHMRC Project Grants       Standard Project Grant                                 Factors family in liver progenitor of development and
                                                                                                                                          University cell proliferation of liver precurso
                                                                                        The role of TNF and its receptorwhich affect the growth and Western Australia differentiatio
262012   Dr David Bowen                                    CJ Martin                                              Hepatitis C virus replication and immunity in the chimpanzee and
                                                                                                                                          Centenary Institute of Cancer Medicine
                                Early Career Fellowships (Overseas) (Biomedical) ECF Hepatitis C virus replication and immunity in the chimpanzee
265603   Dr Mark Berzsenyi                                 Medical                      Associations, outcomesAssociations,of GB virus & genomics of GB virus C, Hepatitis C Vir
                                NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                          Alfred Hospital
                                                                                                                   & genomics outcomes C, Hepatitis C Virus and Human Immuno
268011   Dr Catherine Banwell NHMRC Project Grants         Standard Project Grant                                 Choice or chance: contraceptive National University hepatitis C
                                                                                                                                          Australian by by women with
                                                                                        Choice or chance: the social context of contraceptive useuse women with HCV and their re
293803   A/Pr Mark Gorrell      CARG                       ANCARD Project Grant                                     dipeptidyl peptidase humanPrince human liver
                                                                                                                                          Royal liver
                                                                                        Roles of enzymes of theEnzymes important ingene family in Alfred Hospital
296200   Dr Heidi Drummer       NHMRC Project Grants       Standard Project Grant                                 Structure and function Macfarlane
                                                                                                                                           of HCV glycoproteins
                                                                                        Structure and function of Hepatitis C Virus glycoproteins Burnet Institute for Medical Res
300081   Dr Michelle Kermode Early Career ECFs (Australia) Public Health (Australia) ECF                          Risk of therapeutic injection-realted Melbourne virus transmission
                                                                                                                                          University of blood-borne
                                                                                        Risk of therapeutic injection-realted blood-borne virus transmission amongst IDU and non
300579   Prof Lisa Maher                                   Population Health CDF
                                Career Development Fellowships                                                    Prevention of Blood-borne Virus of New South Wales
                                                                                                                                           among Injecting Drug Users (IDUs)
                                                                                        Prevention of Blood-borne Virus Transmission UniversityTransmission among Injecting Dr
307818   Ms Katerina Ajami                                 Dora Lush
                                NHMRC Postgraduate Scholarships Biomedical Scholarship                            Functions of DipeptidylUniversity of Sydney
                                                                                        Functions of Dipeptidyl Peptidase (DP)9             Peptidase (DP)9
323212   A/Pr David Moore       NHMRC Project Grants       Standard Project Grant                                 Ethno-epidemiology of Curtin University of Technology
                                                                                                                                           psychostimulant-related An integrated ethn
                                                                                        Improving understanding of psychostimulant-related harms in Australia: harms
331309   Prof Peter Gage        NHMRC Project Grants       Standard Project Grant                                 Hepatitis virus
                                                                                        Studies of hepacivirus morphogenesis.assembly.    Macfarlane Burnet Institute for Medical Res
331312   A/Pr Margaret Hellard NHMRC Project Grants        Standard Project Grant                                 and immunological hepatitis C virus infection in injecting drug user
                                                                                                                                          Macfarlane Burnet Institute for Medical Res
                                                                                        Behavioural, virological Factors influencing factors influencing hepatitis C virus infection in
331324   Dr Peter Higgs                                    Public Health Postgraduate Scholarship
                                NHMRC Postgraduate Scholarships                                                   Ethic Vietnamese heroin injectors Burnet Institute for Medical Res
                                                                                                                                          Macfarlane
                                                                                        Ethic Vietnamese heroin injectors and BBV transmission and BBV transmission
334275   Dr Nicholas Walsh                                 Public Health Postgraduate Scholarship of recruitment, engagement and Monash University and management of IDU
                                NHMRC Postgraduate Scholarships                         Determinants                                       management of IDUs
                                                                                                                  Determinants of recruitment, engagement in health care in Aust
334603   Prof Simon Mallal      NHMRC Project Grants       Standard Project Grant                                 Adaptation of HepatitisMurdoch University
                                                                                                                                           C to Host Responses
                                                                                        Adaptation of Hepatitis C to Host HLA-Restricted ImmuneHLA-Type in Australian Popula
349353   Dr MICHAEL BEARD Career Development Fellowships   RD Wright (Biomedical) CDF                              response to HCV infection: its roletoAdelaide
                                                                                                                                          University       modulating liver role in mod
                                                                                        Defining the hepatocyte Defining the hepatocyte responseof inHCV infection: its disease and
351008   A/Pr Carolyn Day                                  Public Health (Australia) ECF
                                Early Career ECFs (Australia)                                                     Impact drug dependence treatmentSydney
                                                                                                                                          University of dependence treatment on He
                                                                                        Impact of injecting patterns andof injecting patterns and drug on Hep C treatment outcome
351579   A/Pr Elizabeth Powell NHMRC Project Grants        Standard Project Grant                                 How fatty cellular injury and fibrogenesis in human liver disease
                                                                                                                                          University of Queensland
                                                                                        The role of steatosis in promoting liver causes fibrosis
351642                                                     Dora Lush
         Miss Meagan Walsh NHMRC Postgraduate Scholarships Biomedical Scholarship                                 Investigation of the mechanisms by Queensland
                                                                                                                                          University of which steatosis contributes
                                                                                        Investigation of the mechanisms by which steatosis contributes to hepatic fibrogenesis to
358398   Prof Geoffrey Farrell Programs                    Program Grant                                          PROCESSES THAT CAUSE LIVERSydney AND CIRRHOSIS O
                                                                                                                                          University of INJURY
                                                                                        MOLECULAR AND CELLULAR PATHOGENESIS OF HUMAN LIVER DISEASE
376043   Dr Kerry-Lee Milner                               Medical                      Physiological basis of insulin resistance in chronic hepatitis C viruschronic ResearchC virus
                                NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                          Garvan Institute in infection
                                                                                                                  Physiological basis of insulin resistanceof Medical hepatitis
381713   Dr Heidi Drummer       NHMRC Project Grants       Standard Project Grant                                 Neutralizing antibody responses inBurnet Institute for Medical
                                                                                                                                          Macfarlane infected individuals.
                                                                                        Characterization of neutralizing antibody responses in HCVHCV infected individuals. Res
381732   A/Pr Rosemary Ffrench                             Industry
                                Career Development Fellowships CDF                                                Development and testing of a novel vaccine strategy
                                                                                        Development and immunogenicity testing of Macfarlane Burnet Institute for Medical Res
384702   Prof Simon Mallal      Programs                   Program Grant                                          Interactions between adaptable pathogens, drugs and the human
                                                                                                                                          Murdoch University
                                                                                        Interactions between adaptable pathogens, drugs and the human host
390708   Dr Karla Helbig                                  Peter Doherty (Biomedical) ECF Factors Modulating the Severity Modulating theVirus Medical and Veterinary Science
                               Early Career ECFs (Australia)                          Host                                                Institute of Infection
                                                                                                                 Host Factors of Hepatitis C Severity of Hepatitis C Virus Infection
399284   Dr MICHAEL BEARD NHMRC Project Grants            Standard Project Grant                                 The role of alcohol, Cyp2e1 of hepatocyte homeostasis cell replic
                                                                                                                                          University of Adelaide
                                                                                      The role of Cyp2e1, alcohol and HCV in modulation and hepatitis C virus in liverHCVbiolog
399285   Dr MICHAEL BEARD NHMRC Project Grants            Standard Project Grant                                 Hepatitis C virus, chemokines and their role in viral hepatitis
                                                                                                                                          University of Adelaide
                                                                                      The role of CXCR3 chemokines in hepatitis C and other forms of viral hepatitis
400920   Prof Andrew Lloyd     NHMRC Project Grants       Standard Project Grant                                 Position and of T cellsUniversity of New South liver liver
                                                                                                                                            T cells in HCV HCV infected
                                                                                      Fine positioning and effector functionfunction ofrecruited to the infected Wales
401146   Ms Heidi Coupland                                Public Health Postgraduate Scholarship and managemnet of hepatitis C infection in Indo-Chinese injecting drug users
                               NHMRC Postgraduate Scholarships                        Prevention                                          University of New C infection in
                                                                                                                 Prevention and managemnet of hepatitis South Wales Indo-Chine
401522                                                    Practitioner Fellowship
         Prof Elizabeth Powell Established Career Fellowships                         Practitioner Fellowship Practitioner FellowshipUniversity of Queensland
402577   Prof Jacob George     NHMRC Project Grants       Standard Project Grant                                 Host factors affecting hepatatis C disease
                                                                                                                                          University
                                                                                      Host determinants of Hepatitis C-associated liver diseaseof Sydney
433900                                                    NHMRC Research Fellowship
         A/Pr David Anderson Established Career Fellowships                                                      Uncoupled                Macfarlane
                                                                                      Uncoupled Research Fellowship Research Fellowship Burnet Institute for Medical Res
433908   Prof Eric Gowans      NHMRC Project Grants       Standard Project Grant                                 Supressor VIRUS-SPECIFIC T virus TOLERANCE Medical Res
                                                                                                                                          Macfarlane Burnet Institute for
                                                                                      UNDERSTANDING HEPATITIS C T cells in hepatitis C CELLinfection
433913   Dr Heidi Drummer      NHMRC Project Grants       Standard Project Grant                                 Structure and C Virus Macfarlane Burnet Institute
                                                                                                                                          of the Hepatitis C Virus glycoproteins E1 an
                                                                                      Structure and function of the Hepatitis function glycoproteins E1 and E2. for Medical Res
433929   A/Pr Heidi Drummer Career Development FellowshipsRD Wright (Biomedical) CDF                             Structure and C Virus Macfarlane Immunodeficiency VirusImmun
                                                                                                                                          of the Hepatitis C Virus and Human glycop
                                                                                      Structure and function of the Hepatitis function and Human Burnet Institute for Medical Res
433935                                                    Public Health Postgraduate Scholarship and maintenance of T cell responses in acute HCV infection in acute HCV inf
         Dr Jacqueline Flynn NHMRC Postgraduate Scholarships                          Stimulation                                         Macfarlane Burnet Institute
                                                                                                                 Stimulation and maintenance of T cell responses for Medical Res
433941                                                    Dora Lush                   Role of                    Role of the variable regions of Hepatitis C Institute in Medical Res
                                                                                                                                          Macfarlane Burnet Virus envelope glycopro
         Ms Kathleen McCaffreyNHMRC Postgraduate Scholarships Biomedical Scholarship the variable regions of Hepatitis C Virus envelope glycoprotein E2 forglycoprotein s
436729   A/Pr Hans Netter      NHMRC Project Grants       Standard Project Grant                                 Design of vaccination the prevention of hepatitis C and influenza o
                                                                                                                                          Monash University
                                                                                      Novel generic vaccine approaches applied for tools directed against infectious pathogens v
448325   Dr Kim Wilson         NHMRC Project Grants       Standard Project Grant                                  the Humoral Immune Response to HCV to of Medical C Virus and
                                                                                                                                           Immune Response identify Diagnostic
                                                                                      Detailed Investigation ofCharacterisation of theSt Vincent's Instituteto Hepatitis Research
454640   A/Pr David Jackson NHMRC Project Grants          Standard Project Grant                                 A New Method for Vaccine Design Melbourne
                                                                                                                                          University of
                                                                                      Using the Information inherent in Immune Responses to Design Vaccines
455355   Prof Gregory Dore                                Practitioner Fellowship
                               Established Career Fellowships                         Practitioner Fellowship Practitioner FellowshipUniversity of New South Wales
455985   A/Pr Julie Jonsson    NHMRC Project Grants       Standard Project Grant                                 A new model progenitor cells and liver disease
                                                                                                                                          University of Queensland
                                                                                      Hepatocyte replicative arrest, hepatic for fibrosis in chronicthe ductular reaction in hepatic
457043   Dr Patrick Bertolino  NHMRC Project Grants       Standard Project Grant                                 Rapid T cell clearance University of Sydney
                                                                                                                                          by the liver
                                                                                      Understanding rapid T-cell clearance by the liver: a critical step towards improved liver tra
508088   A/Pr Michael Beard    NHMRC Project Grants       Standard Project Grant                                 Host genes that control limit replication and and predict therapeu
                                                                                                                                          University of Adelaide
                                                                                      Identification of interferon stimulated genes that HCV HCV replicationpredict treatment resp
508950   Prof David Jackson                               NHMRC Research Fellowship
                               Established Career Fellowships                                                    Uncoupled                University
                                                                                      Uncoupled Research Fellowship Research Fellowship of Melbourne
510246   Prof Andrew Lloyd                                Practitioner Fellowship
                               Established Career Fellowships                         Practitioner Fellowship Practitioner FellowshipUniversity of New South Wales
510424   Dr Peter Higgs                                   Public Health (Australia) ECF
                               Early Career ECFs (Australia)                                                     How do long term injecting drug users avoid hepatitis C
                                                                                                                                          University of New South Wales
                                                                                      Staying safe: How do long term injecting drug users avoid hepatitis C infection? infection?
510428   Dr Fabio Luciani                                 Peter Doherty (Biomedical) ECF
                               Early Career ECFs (Australia)                                                     Improving the design integrating for Hepatitis C virus immunolog
                                                                                                                                          University large sequence- and
                                                                                      Modelling the evolution of Hepatitis C virus byof vaccines of New South Wales by predicting
511201   Prof Elizabeth Powell NHMRC Project Grants       Standard Project Grant                                 Role of obesity in impaired treatment response in
                                                                                                                                           in chronic hepatitis C: mechanisms and the
                                                                                      Role of obesity in impaired treatment responseUniversity of Queensland chronic hepatitis
511219   Dr Ingrid Hickman     NHMRC Project Grants       New Investigator Grant                                 Obesity and liver disease: Contributors to liver injury and the and
                                                                                                                                          University of Queensland
                                                                                      Obesity-related inflammation and insulin resistance in chronic liver disease: Exerciserole o
511902   Prof Paul Haber                                  Practitioner Fellowship
                               Established Career Fellowships                         Practitioner Fellowship Practitioner FellowshipUniversity of Sydney
512031                                                    Medical                     The effect of exercise on insulin resistance and patients withSydney hepatitis C.
         Dr Venessa Pattullo NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                               the adipokine profile
                                                                                                                 Lifestyle intervention inUniversity of chronic in obese versus non
512284   Dr David Bowen        NHMRC Project Grants       New Investigator Grant                                 Immune immune responses post-liver transplantation
                                                                                                                                          University of Sydney
                                                                                      Hepatitis C virus-specific cellularresponses to the hepatitis C virus following liver transplan
513896   Prof George Yeoh      NHMRC Project Grants       Standard Project Grant                                  growth, lineage commitment and develop into functional liver cells
                                                                                                                                            grow       differentiation of liver
                                                                                      Mechanisms underlyingHow do liver stem cellsUniversity of Western Australia progenitor
513961   Dr Aibin Zhang                                   Australia - Fellowships     Role of TNF-á in growth, lineage commitment and differentiation of liver progenitor cells
                               International (Exchange) Early Career China Exchange Fellowship                                            University
                                                                                                                 TNF-á and liver progenitor cells of Western Australia
520312                         NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship
         Dr Douglas - INACTIVATED Johnson                 Medical                                                Vaccine development and antibody Melbourne
                                                                                                                                          University of response using Hepatitis C vir
                                                                                      Humoral and neutralising antibody responses to self-adjuvanting recombinant HCV virus l
510448   Prof David Cooper     Programs                   Program Grant                                          and Immunopathogenesis.   Hepatitis of
                                                                                      HIV and HCV Vaccines Vaccines for AIDS andUniversity C. New South Wales
543113   A/Pr Heidi Drummer NHMRC Project Grants          Standard Project Grant                                 How variable regions in HCV E2 modulateInstitute for antibody me
                                                                                                                                          Macfarlane Burnet glycoprotein function.
                                                                                      Role of the hepatitis C virus glycoprotein E2 variable regions in viral entry andMedical Res
543137                         NHMRC Project Grants
         A/Pr Anthony Jaworowski                          Standard Project Grant                                  in chronic viral disease
                                                                                      ITAM signalling proteinsHow HIV causes disease      Macfarlane Burnet Institute for Medical Res
543143   Prof Eric Gowans      NHMRC Project Grants       Standard Project Grant                                 A hepatitis C virus.
                                                                                      Multiple vector vaccine fornovel HCV vaccine University of Adelaide
543144     Prof Eric Gowans      NHMRC Project Grants      Standard Project Grant                                  to treat HCV infection.University of Adelaide
                                                                                        A novel immunotherapyA new HCV cell therapy.
567057                           E                         CJ Martin                                              Genetic determinants of clinical outcome and treatment response
                                                                                                                                            University of Melbourne
           Dr Alexander Thompsonarly Career Fellowships (Overseas) (Biomedical) ECF A whole genome association study for determinants of clinical outcome and treatment resp
567174     Miss Sarah Moneer                               Dora Lush                    Immune                    Innate immunity HCV -University of infection cells and NKR expre
                                                                                                                                             a potential role for NK
                                 NHMRC Postgraduate Scholarships Biomedical Scholarship correlates of protection against in Hepatitis C virus Melbourne
568859     Dr Mark Danta         NHMRC Project Grants      Standard Project Grant                                 Defining permucosal transmission for acute HCV infection
                                                                                                                                            University of New C among gay
                                                                                        Defining risk and mechanisms ofsexual transmisison of hepatitis South Wales menwithin
568885     Prof John Kaldor                                Centre                       Centre for                Centre for Clinical Aboriginal Health: Sexually transmitted and blo
                                                                                                                                            University of New South Wales
                                 Centres for Research Excellence of Clinical Research Excellence Clinical Research Excellence in Research Excellence in Aboriginal Health: Sexu
568985     Prof Gregory Dore     NHMRC Partnerships                                     Evaluation                Assessment and treatment of hepatitis C Southamong injecting dru
                                                                                                                                            University of New virus Wales
                                                           Partnership Projects for Better Health of a model for assessment and treatment of HCV among injecting drug users in
594444     Prof Tony Butler      NHMRC Project Grants      Standard Project Grant                                   Treatment Prisons and Treatment New South Wales
                                                                                                                                            University of Opportunities (HePATO)
                                                                                        Hepatitis C, Prisons andHepatitis C, Opportunities (HePATO)
603735     A/Pr Heidi Drummer NHMRC Project Grants         Standard Project Grant                                 Structure and FunctionMacfarlane glycoproteins
                                                                                                                                             of
                                                                                        Structure and Function of the HCV glycoproteins the HCVBurnet Institute for Medical Res
 603755                                                    Public Health Postgraduate Scholarship between phylogenydont lie: predicting sourcessocial network structure socia
           Rachel Sacks-Davis NHMRC Postgraduate Scholarships                           Relationships                                       Macfarlane Burnet Institute for Medical Res
                                                                                                                  Genetics of hepatitis C viruses and of HCV infections from in a c
 603756                                                    Public Health Postgraduate Scholarshipdrug-related Examining drug-related and sevice Burnet Institute forex-prisoners
           Ms Rebecca Winter NHMRC Postgraduate Scholarships                            Examining                                             morbidity utilisation among Medical Res
                                                                                                                  morbidity and mortalityMacfarlaneand mortality and sevice utilisati
 626906    A/Pr Michael Beard                              NHMRC Research Fellowship
                                 Established Career Fellowships                                                   Uncoupled                 University
                                                                                        Uncoupled Research Fellowship Research Fellowship of Adelaide
 628953    Dr Eu Jin Lim                                   Medical                      The Effects of Hepatitis The Effects of Hepatitis CFibrosisof Melbourne of Immunosuppre
                                 NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                           University In The Medications on The Live
                                                                                                                  C Viral Proteins On Liver and TransplantSetting
 630463    A/Pr David Wilson     NHMRC Project Grants      Standard Project Grant                                 Modelling and hepatitisUniversity of New South Wales in Austral
                                                                                                                                              C epidemic hepatitis strategies
                                                                                        Modelling and economic evaluation of cost-effectiveness of mitigationC biomedical interven
 630483    Prof Lisa Maher       NHMRC Project Grants      Standard Project Grant                                 Hepatitis C Vaccine Preparedness StudySouth Wales
                                                                                                                                            University of New
                                                                                        Hepatitis C Vaccine Preparedness Study: Investing in Infectious Disease Prevention
 630733    Dr Rowena Bull                                  Peter Doherty (Biomedical) ECF
                                 Early Career ECFs (Australia)                                                    Understanding hepatitis C virus infection
                                                                                                                                             C virus chronicity
                                                                                        Virus-host interactions contributing to hepatitis University of New South Wales
 630754    Bethany White                                   Public Health Postgraduate Scholarship vaccine preparedness: feasibilitypreparedness vaccine trials
                                 NHMRC Postgraduate Scholarships                        Hepatitis C                                           field-based
                                                                                                                  Hepatitis C Vaccine ofUniversity of New South Wales
 637350    Dr Marc Pellegrini                              Clinical
                                 Career Development Fellowships CDF                                               Indentifying new signalling for chronic viral Institute
                                                                                                                                            Walter and Eliza promote immune clearan
                                                                                        Trageted manipulation of host genes andtreatments pathways toHall diseases
1003741                                                    RD Wright (Biomedical) CDF
           Dr Meredith O'Keeffe Career Development Fellowships                                                    immunity and their dendritic cells in the first line defense agains
                                                                                                                                            Macfarlane Burnet Institute
                                                                                        Dendritic cells in innate The involvement ofpotential clinical manipulation offor Medical Res
1003767    Prof Jacob George     NHMRC Project Grants      Standard Project Grant                                 Endocannabinoids in chronic
                                                                                                                                            University of Sydney
                                                                                        The role of endocannabinoids in chronic hepatitis C hepatitis C
1004242                                                    Practitioner Fellowship
           Prof Elizabeth Powell Established Career Fellowships                                                   The role of obesity, insulin resistance andhuman
                                                                                                                                             liver (steatosis) in fatty liver (steatosis) in
                                                                                        The role of obesity, insulin resistance and fattyUniversity of Queensland disease and strah
1006331    Dr Gail Matthews      NHMRC Project Grants      Standard Project Grant                                 Evidence for naturally Direct Acting New South Wales
                                                                                                                                            University of Antiviral Drugs (DAAs) drugs
                                                                                        Evaluation of naturally occurring resistance to occurring resistance to antiviral HCV in indiv
1006592    Dr Marc Pellegrini    NHMRC Project Grants      New Investigator Grant                                 Understanding host immune mediated pathology: an analysis and
                                                                                                                                            Walter and Eliza clearance of
                                                                                        Chronic active viral persistence versus the host factors that limitHall Institute chronic virus
1006759    A/Pr David Booth      NHMRC Project Grants      Standard Project Grant                                 IL28B and hepatitis virus infection Sydney
                                                                                        The effect of IL28B haplotype on hepatitis CC University of and treatment response
1011319    Prof Ian James        NHMRC Project Grants      Standard Project Grant                                 Statistical host-viral genetic association
                                                                                                                                            Murdoch University
                                                                                        Statistical issues in the analysis ofissues in host-viralassociations studies
1016351    Prof Andrew Lloyd     NHMRC Partnerships                                     Prevention                Prevention and treatment of viral of New South Wales
                                                                                                                                            University hepatitis amongst prisoners
                                                           Partnership Projects for Better Health and treatment of viral hepatitis amongst prisoners
1017139    Dr Paul Clark                                   Medical                      Individualising care for patients with chronicof patients with chronicside Wales and treatm
                                 NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                           University of New South effects
                                                                                                                  Individualising care hepatitis C: predicting hepatitis C
1017465    Mr Jesse Toe                                                                 Clearing                                            Walter immune Hall Institute
                                                                                                                  Clearing chronic infectious diseases – enhancing host immune eff
                                 NHMRC Postgraduate Scholarships Biomedical Scholarship chronic infectious diseases – enhancing hostand Eliza effector function
                                                           Dora Lush
1018023    Dr Joseph Doyle                                 Medical                      Early Treatment           Early Treatment of Hepatitis C Virus in Australia for Medical Res
                                 NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship of Hepatitis C Virus in Australia         Macfarlane Burnet Institute
1018079    Dr Kate O'Connor                                Medical                      Functional pharmacogenetics: Analysisfunctional effect ofof Sydney genotype on respons
                                 NHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                                           University the of the
                                                                                                                  Analysis of the of the functional effectIL28B IL28B genotype on h
1020175    A/Pr Heidi Drummer NHMRC Project Grants         Standard Project Grant                                 virus glycoprotein E2 variable regions in Institute for Medical Res
                                                                                                                                            Macfarlane Burnet
                                                                                        Roles of the hepatitis C Variable regions of HCV glycoprotein E2 virus entry, immunogenic
1022144    Dr Michael Gantier    NHMRC Project Grants      New Investigator Grant                                 antiviral responses       Monash University
                                                                                        microRNA regulation of microRNA regulation of antiviral responses
1023437    Prof Carla Treloar    NHMRC Project Grants      Standard Project Grant                                 Hepatitis C transmission and intimate sexual partnerships
                                                                                                                                            University of New South
                                                                                        Understanding and preventing hepatitis C transmission within injectors Wales
1027641    A/Pr Michael Beard    NHMRC Project Grants      Standard Project Grant                                 Imaging cycle in real-time life of Adelaide
                                                                                                                                              virus
                                                                                        Imaging the hepatitis C virus life the hepatitis CUniversitycycle in living cells
 1028432   Prof Gregory Dore                               Practitioner Fellowship
                                 Established Career Fellowships                         Practitioner Fellowship Practitioner FellowshipUniversity of New South Wales
 1032096   Dr Amany Zekry        NHMRC Project Grants      New Investigator Grant                                  of liver injury in chronicchronic hepatitis South Wales
                                                                                                                                               hepatitis of
                                                                                        Inflammatory mediators Liver inflammation andUniversity C New C
 1035383   Dr Jason Grebely                                Population Health CDF
                                 Career Development Fellowships                                                   Epidemiology, natural University treatment of Wales injecting dru
                                                                                                                                            hepatitis C virus infection in in
                                                                                        Epidemiology, natural history and treatment of history andof New SouthHCVinjecting drug u
                                                  Medical                    Studies on the pathogenesis and early pathogenesis and of Sydney
1039019 Dr Roslyn VongsuvanhNHMRC Postgraduate ScholarshipsPostgraduate Research Scholarship                              University early diagnosis of hepatocellular
                                                                                                   Studies on the diagnosis of hepatocellular carcinoma
1039597 Prof Paul Hertzog                         Development Grant
                            NHMRC Development Grants                                               Development of new antivirals. University
                                                                             Development of new antivirals.               Monash
        App    Start
State                  1995   1996   1997   1998   1999   2000   2001   2002   2003   2004   2005   2006
        Year   Year
VIC   1994   1995 $38,283 $100,333 $90,668 $122,478 $34,282                $76,979
WA    1995   1996          $16,864 $2,864 $14,273 $17,635        $8,884
NSW   1996   1997                  $34,689 $66,833 $75,870      $65,759    $34,176
QLD   1997   1998                          $105,555 $117,876    $99,385
NSW   1997   1999                                    $15,461    $29,747    $29,792
VIC   1997   1999                                    $40,094    $29,906
VIC   1997   1999                                    $54,956    $40,044
NSW   1997   1999                                    $18,407    $41,593
VIC   1997   1999                                    $41,010    $18,990
QLD   1997   1999                                    $26,292    $29,744    $18,964
VIC   1997   1999                                    $41,333    $57,203    $36,464
NSW   1997   1999                                    $24,629    $20,371
NSW   1997   1999                                    $32,181    $66,352    $66,467
WA    1997   1999                                    $25,765    $16,235
VIC   1997   1999                                    $30,179    $99,821
VIC   1997   2000                                               $37,500    $27,500
NSW   1998   1999                                   $131,278   $113,348   $130,889     $3,280
NSW   1998   1999                                   $155,313   $135,033   $152,562
QLD   1998   1999                                    $70,428    $62,365    $67,944     $2,991
WA    1998   1999                                    $25,497    $26,889    $27,255    $13,782      $632
VIC   1999   2000                                               $56,296    $29,613
VIC   1999   2000                                               $38,173    $79,157    $78,325    $63,500
NSW   1999   2000                                               $18,571    $18,842    $19,214     $9,749                 $443
VIC   1999   2000                                               $26,889    $27,255    $27,793
NSW   1999   2000                                               $26,889    $27,255               $14,904
VIC   1999   2000                                               $65,418    $66,882    $66,713
QLD   1999   2001                                                         $199,522   $135,359
VIC   1999   2000                                              $172,182   $241,605   $130,081
VIC   2000   2001                                                         $107,785   $108,121
NSW   2000   2001                                                          $65,285    $65,621    $65,621
NSW   2000   2001                                                          $70,380    $70,828    $70,828
NSW   2000   2001                                                          $27,255    $27,793    $28,432      $508
VIC   2000   2001                                                          $70,285    $70,621    $70,621    $70,621    $76,621
VIC   2000   2001                                                          $66,366    $95,000    $99,250   $116,250   $118,500   $120,500
VIC   2000   2001                                                         $120,475   $121,035   $121,035
NSW   2000   2001                                                          $95,285   $100,828
NSW   2000   2001   $27,255    $27,793    $14,099
VIC   2001   2002             $150,770   $150,770   $150,770
VIC   2001   2002             $130,000   $135,000   $106,875
SA    2001   2002             $125,440   $125,440   $125,440
QLD   2001   2002              $82,330    $82,330    $82,330
VIC   2001   2002             $135,550   $135,550   $135,550
QLD   2001   2002              $24,328    $24,889    $10,612
NSW   2002   2003                        $187,000   $187,000   $187,000    $187,000
NSW   2002   2003                          $9,910    $20,484    $24,941     $14,675
VIC   2002   2003                        $126,000   $125,625   $130,625     $37,500
VIC   2002   2003                         $14,704    $20,484    $20,837     $15,938
VIC   2002   2003                         $19,659    $20,484    $20,837
WA    2002   2003                         $83,500    $83,500    $83,500
NSW   2002   2003                         $77,040    $87,232    $21,427     $74,750
VIC   2003   2004                                    $29,489    $30,014     $30,600
ACT   2003   2004                                   $144,525   $115,625
NSW   2003   2005                                               $79,750
VIC   2003   2004                                   $160,250   $160,250    $160,250
VIC   2003   2004                                    $64,750    $66,000     $67,250
NSW   2003   2004                                    $85,250    $87,250     $89,000
NSW   2003   2004                                    $20,484    $20,837     $21,231
WA    2004   2005                                              $215,810    $225,810
VIC   2004   2005                                              $160,250    $160,250
VIC   2004   2005                                              $323,375    $359,375
VIC   2004   2005                                               $26,309     $26,817
VIC   2004   2005                                               $55,326     $30,600
WA    2004   2005                                              $160,250    $160,250
SA    2004   2005                                               $87,250     $89,000
NSW   2004   2005                                               $66,000     $38,333
QLD   2004   2005                                              $138,125    $138,125
QLD   2004   2005                                               $20,838     $21,231
NSW   2004   2005                                              $947,387    $965,387
NSW   2005   2006                                                           $16,300
VIC   2005   2006                                                          $154,250
VIC   2005   2006
WA    2005   2006                                                         $1,173,888
SA    2005   2006    $67,250
SA    2005   2006   $148,500
SA    2005   2006   $149,250
NSW   2005   2006   $108,375
NSW   2005   2006    $21,231
QLD   2005   2006    $56,625
NSW   2005   2006   $211,700
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2008
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
VIC   2006   2007
NSW   2006   2007
QLD   2006   2007
NSW   2006   2007
SA    2007   2008
VIC   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2007   2008
QLD   2007   2008
QLD   2007   2008
NSW   2007   2008
NSW   2007   2008
NSW   2007   2008
WA    2007   2008
WA    2007   2008
VIC   2007   2008
NSW   2008   2009
VIC   2008   2009
VIC   2008   2009
SA    2008   2009
SA    2008   2009
VIC   2008   2009
VIC   2008   2009
NSW   2008   2009
NSW   2008   2009
NSW   2008   2010
NSW   2009   2010
VIC   2009   2010
VIC   2009   2010
VIC   2009   2010
SA    2009   2010
VIC   2009   2010
NSW   2009   2010
NSW   2009   2010
NSW   2009   2010
NSW   2009   2010
VIC   2009   2010
VIC   2010   2011
NSW   2010   2011
QLD   2010   2011
NSW   2010   2011
VIC   2010   2011
NSW   2010   2011
WA    2010   2011
NSW   2010   2011
NSW   2010   2011
VIC   2010   2011
VIC   2010   2011
NSW   2010   2011
VIC   2011   2012
VIC   2011   2012
NSW   2011   2012
SA    2011   2012
NSW   2011   2012
NSW   2011   2012
NSW   2011   2012
NSW   2011   2012
VIC   2011   2012

                    Expenditure $1,403,587 $2,009,494 $1,813,596 $1,730,463 $1,848,513 $3,445,377 $5,141,241
                     # of grants    26         28         24         24         22         28         32
                                                                              Broad Research
2007   2008   2009   2010   2011   2012   2013   2014   2015   2016   Total
                                                                                   Area
$463,022   Basic Science
 $60,520   Basic Science
$277,327   Clinical Medicine and Science
$322,816   Basic Science
 $75,000   Public Health
 $70,000   Public Health
 $95,000   Basic Science
 $60,000   Public Health
 $60,000   Basic Science
 $75,000   Public Health
$135,000   Public Health
 $45,000   Public Health
$165,000   Public Health
 $42,000   Public Health
$130,000   Public Health
 $65,000   Public Health
$378,794   Public Health
$442,908   Public Health
$203,728   Basic Science
 $94,055   Clinical Medicine and Science
 $85,909   Public Health
$259,155   Public Health
 $66,819   Basic Science
 $81,937   Public Health
 $69,048   Clinical Medicine and Science
$199,014   Clinical Medicine and Science
$334,881   Basic Science
$543,868   Public Health
$215,906   Public Health
$196,528   Basic Science
$212,037   Clinical Medicine and Science
 $83,988   Clinical Medicine and Science
$358,770   Basic Science
$615,866   Basic Science
$362,546   Basic Science
$196,113   Public Health
                                                   $69,147   Clinical Medicine and Science
                                                 $452,310    Basic Science
                                                 $371,875    Public Health
                                                 $376,320    Clinical Medicine and Science
                                                 $246,990    Clinical Medicine and Science
                                                 $406,650    Basic Science
                                                   $59,829   Public Health
 $200,250                                        $948,250    Clinical Medicine and Science
    $270                                           $70,281   Public Health
                                                 $419,750    Public Health
                $579                               $72,541   Public Health
     $627                                          $61,607   Basic Science
                                                 $250,500    Basic Science
  $38,000                                        $298,449    Basic Science
  $15,668                                        $105,771    Clinical Medicine and Science
                                                 $260,150    Public Health
                                                   $79,750   Basic Science
                                                 $480,750    Basic Science
   $68,500                                       $266,500    Public Health
   $90,500    $92,500                            $444,500    Public Health
   $10,963      $442         $314                  $74,271   Basic Science
 $170,810                                        $612,430    Public Health
 $160,250                                        $480,750    Basic Science
 $280,688                                        $963,438    Public Health
   $27,563                                         $80,689   Public Health
   $15,754                                       $101,680    Public Health
 $160,250                                        $480,750    Clinical Medicine and Science
   $90,500    $92,500     $94,250                $453,500    Clinical Medicine and Science
   $68,500    $69,750     $45,313    $51,375     $339,271    Public Health
 $138,125                                        $414,375    Clinical Medicine and Science
   $10,963      $676                               $53,708   Clinical Medicine and Science
 $965,387 $1,024,681    $1,025,481              $4,928,324   Clinical Medicine and Science
   $15,754    $30,881      $23,350                 $86,285   Clinical Medicine and Science
 $157,628 $166,198                               $478,077    Basic Science
   $92,250 $147,042        $96,250    $85,728    $421,270    Clinical Medicine and Science
$1,197,366 $1,197,366   $1,120,613 $1,038,095   $5,727,327   Clinical Medicine and Science
 $68,500    $69,750     $71,250                                                  $276,750    Basic Science
$151,878   $155,142                                                              $455,521    Clinical Medicine and Science
$152,431   $155,586                                                              $457,268    Clinical Medicine and Science
$100,463   $113,136                                                              $321,974    Clinical Medicine and Science
 $21,866    $22,257                                                                $65,354   Public Health
 $55,500    $61,125     $61,250    $62,392                                       $296,892    Clinical Medicine and Science
$216,560   $182,116                                                              $610,376    Clinical Medicine and Science
$119,000   $121,500    $123,750 $126,101 $128,371 $130,553                       $749,275    Clinical Medicine and Science
$140,225   $143,243    $146,242                                                  $429,710    Basic Science
$174,200   $177,950    $181,679                                                  $533,828    Basic Science
            $90,500      $90,500    $94,250    $97,769    $99,431                $472,450    Basic Science
 $21,866    $22,257      $22,677    $12,409                                        $79,209   Clinical Medicine and Science
 $21,866    $22,257      $22,677    $12,409                                        $79,209   Basic Science
$128,075   $130,700    $133,554                                                  $392,328    Basic Science
$126,500   $129,036    $131,931                                                  $387,467    Basic Science
$144,675   $188,907    $192,990                                                  $526,572    Clinical Medicine and Science
           $163,275      $84,175    $85,774    $87,318                           $420,542    Clinical Medicine and Science
$172,250   $175,821    $179,612                                                  $527,683    Clinical Medicine and Science
$134,550   $137,282    $140,302                                                  $412,134    Basic Science
           $127,110    $129,825 $132,290                                         $389,225    Clinical Medicine and Science
           $150,250    $153,250 $156,161 $158,972 $142,949                       $761,582    Clinical Medicine and Science
            $98,875    $100,975 $102,893 $104,745 $106,526                       $514,014    Clinical Medicine and Science
            $17,438      $71,250    $72,508    $73,813    $56,301                $291,310    Public Health
            $34,875      $71,250    $72,508    $73,813    $37,534                $289,980    Basic Science
           $176,340    $180,157 $183,578                                         $540,075    Clinical Medicine and Science
           $115,800    $212,985 $211,724                                         $540,510    Clinical Medicine and Science
            $58,875      $60,125    $61,267    $62,370    $63,430                $306,067    Clinical Medicine and Science
            $32,003      $32,628    $35,750                                      $100,381    Clinical Medicine and Science
           $181,035    $143,239 $145,959                                         $470,233    Clinical Medicine and Science
           $174,800    $178,571 $181,962                                         $535,333    Basic Science
           $107,550    $121,039                                                  $228,589    Clinical Medicine and Science
            $32,003      $32,628    $35,750    $18,415                           $118,796    Basic Science
                      $3,617,780 $3,686,518 $3,750,361 $3,811,741 $3,811,741   $18,678,141   Clinical Medicine and Science
                       $177,500 $180,871 $184,091                                $542,462    Basic Science
                       $149,175 $152,008 $154,716                                $455,899    Basic Science
                       $154,275 $177,477 $165,290                                $497,041    Clinical Medicine and Science
$168,249   $190,749   $209,091                                                       $568,088    Clinical Medicine and Science
$100,686    $95,166    $81,448    $82,833                                            $360,133    Clinical Medicine and Science
 $22,677    $24,750    $25,327                                                         $72,754   Basic Science
$136,175   $128,368   $130,639                                                       $395,182    Public Health
$500,000   $500,000   $509,000   $517,653   $517,653                                $2,544,306   Clinical Medicine and Science
           $299,188   $304,382   $309,556   $309,556                                $1,222,683   Health Services Research
           $197,112    $54,068                                                       $251,179    Public Health
           $196,156   $199,666   $203,041                                            $598,864    Basic Science
            $24,750    $25,110    $26,479                                              $76,339   Public Health
            $24,750    $25,110    $26,479                                              $76,339   Public Health
           $114,128   $116,182   $118,157   $118,157   $118,157                      $584,783    Basic Science
            $35,750    $36,286    $38,079                                            $110,115    Basic Science
           $152,339   $155,079   $157,714                                            $465,133    Public Health
           $275,714   $275,468   $269,586                                            $820,767    Public Health
            $72,508    $73,813    $36,240    $56,301    $75,068                      $313,930    Basic Science
            $18,647    $25,110    $13,525                                              $57,282   Public Health
            $96,040    $97,769    $99,431    $99,431                                 $392,670    Clinical Medicine and Science
                      $108,142   $109,981   $109,981   $109,981                      $438,084    Basic Science
                      $184,390   $177,172   $197,878                                 $559,440    Clinical Medicine and Science
                       $62,370    $63,430    $63,430    $63,430   $63,430            $316,090    Clinical Medicine and Science
                      $167,216   $166,563                                            $333,779    Clinical Medicine and Science
                      $137,161   $139,493   $139,493                                 $416,147    Basic Science
                      $187,637   $175,297   $159,767                                 $522,701    Clinical Medicine and Science
                       $86,261    $82,551    $82,551                                 $251,364    Basic Science
                      $356,278   $369,789   $369,789                                $1,095,855   Health Services Research
                       $36,286    $19,290                                              $55,576   Clinical Medicine and Science
                       $25,110    $25,979    $26,479                                   $77,567   Basic Science
                       $36,286    $37,579    $38,079                                 $111,945    Clinical Medicine and Science
                       $36,286    $38,079                                              $74,365   Clinical Medicine and Science
                                 $223,633   $223,633   $223,633                      $670,900    Basic Science
                                 $158,876   $169,046   $163,961                      $491,882    Basic Science
                                 $130,891   $125,806   $120,085                      $376,782    Public Health
                                 $156,389   $156,389   $156,389                      $469,168    Clinical Medicine and Science
                                 $106,526   $106,526   $106,526 $106,526 $106,526    $532,628    Clinical Medicine and Science
                                 $114,413   $114,413   $114,413                      $343,238    Basic Science
                                  $99,431    $99,431    $99,431 $99,431              $397,724    Public Health
                                                                     $37,618    $38,118                       $75,735 Clinical Medicine and Science
                                                         $211,209   $211,209                                 $422,418 Basic Science

$5,926,971 $6,391,409 $10,502,599 $9,603,872 $8,827,015 $8,953,809 $7,344,357 $1,389,192 $269,387 $106,526 $78,278,735
    40         43         43          42         42         41         24         12        3        1
 Field Of   Research Research Research Research Research   Health   Health   Health   Health   Health KW           Media
                                                                                                         Status
Research      KW 1     KW 2     KW 3     KW 4     KW 5     KW 1     KW 2     KW 3     KW 4         5              Summary
Medical Virology                                                                                                                              Closed Media Summary not available
                               C
Medical Virology HEPATITISGENOTYPES                  CELLULARVIRAL IMMUNITY
                                         RECOMBINANT PEPTIDES PERSISTENCE                                                                     Closed Media Summary not available
                  HEPATITISIMMUNOPATHOGENESIS CLEARANCE
                               C
Immunology not elsewhere classified      INFLAMMATIONVIRAL        CHEMOKINES                                                                  Closed Media Summary not available
                               C VIRUS REPLICATION
Medical Virology HEPATITISMOLECULAR EVENTS           CONTROL MECHANISMS                                                                       Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Counselling                                                                                                                            Closed Media Summary not available
Medical Virology                                                                                                                              Closed Media Summary not available
Medical Virology                                                                                                                              Closed Media Summary not available
Medical Virology                                                                                                                              Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
Health Promotion                                                                                                                              Closed Media Summary not available
Medical Virology                                                                                                                              Closed Media Summary not available
Health Information Systems (incl. Surveillance)                                                                                               Closed Media Summary not available
                               C VIRUS IMMUNOTHERAPY DENDRITIC CELLS
Medical Virology HEPATITISVIRUS INFECTION IMMUNE PERTURBATION                                                                                 Closed Media Summary not available
                               C         NATURAL CYTOTOXIX T MICE
Medical Virology HAPATITISINTERFERON-ALPHAKILLER CELLS CELL       SCID                                                                        Closed Media Summary not available
Epidemiology                   C
                  HEPATITISETHNIC HEALTH             HEALTH ACCESS TO
                                         WOMEN'S INJECTING DRUG USE HEALTH CAR                                                                Closed Media Summary not available
                  Health Services not elsewhere classified
                               C
Public Health and HEPATITISPREVELANCE    CHRONIC CARRIAGE                                                                                     Closed Media Summary not available
                             IMMUNOPATHOGENESIS
                                          C
Medical Virology CHRONIC HEPATITISVIRAL CLEARANCE                                                                                             Closed Media Summary not available
Epidemiology      HEPATITISASIAN WOMEN   QUALITY OF LIFE                                                                                      Closed Media Summary not available
                  HEPATITISPRIMARY INFECTIONVIRAL CLEARANCE
Infectious Diseases            C VIRUS CLINICAL                                                                                               Closed Media Summary not available
                             hepatitis C virus
Medical Virology cell-mediated immunity  protection vaccine                   hepatitis C infection virus persistence
                                                                  virus-like particle      liver disease                                      Closed The aim is to evaluate the efficiency
                             Biogenesis Flavivirus Helper system flavivirus infectionencephalitisin
                                          of membranes induced by Kunjin virus as hepatitis a Targets for design of antiviral chemotherapy
                                                                  Roles replication induced membranesrelated flavivirus infections
                                                                              Australian Creating and                                         Closed
Medical Virology Assembly of flavivirus particles replication usingforof flavivirus ofa model C virusvitro replication system for hepatitis C virus Flaviviruses are the agents of many m
Epidemiology                 m           social network
                  ethnography olecular epidemiology analysis                                virus      prevention of transmission
                                                                              Hepatitis C injecting drug use                                  Closed The hepatitis C virus (HCV) continue
                  Health to health care Hepatitis C Men's
                             Health promotion
Public Health and Access Services not elsewhere classifiedHealth              Hepatitis C Injecting Drug Use
                                                                  Stigma of HCV                                    S                          Closed
                                                                                                       Men's health ocial and Behavioural Research This study will identify the health and
Hepatology                   Hepatic stellate cells tissuechronic hepatitis, fibrosis, cirrhosis
                                         Pathogenesis of                       extracellular matrix Hepatitis B Hepatitis C hepatocellular carcinoma
                  Cell surface peptidases and gelatinases remodelling andChronic hepatitis Cirrhosis                                          Closed Chronic liver diseases, particularly th
Hepatology                   gene expression profiling
                                         inflammation
                  Pathogenesis of chronic hepatitis, fibrosis, cirrhosis      autoimmune hepatitis hepatitis C virus infection carcinoma
                                                                                           chronic hepatitis       hepatocellular cirrhosis
                                                                                                                                liver         Closed The incidence of hepatitis C virus (HC
                  Cellular immunology Hepatitis C injecting drug clearance
                              not elsewhere classified
                                                     virus        Viral
Medical and Health Sciences Exposed seronegative Thalassaemia users                                                                           Closed Media Summary not available
                             Polarized Transcytosis iral pathogenesis
Medical Virology Chronic viral infectionepithelia    V            Virus release
                                                                              Chronic hepatitis B hepatitis C transmitted hepatitis
                                                                                           Chronic     Enterically Viral hepatitis
                                                                                                                                Viral infections
                                                                                                                                              Closed The viruses causing hepatitis in man
Not Allocated     N/A                                                                                                                         Closed Media Summary not available
                              virus      fusion
Medical Virology Hepatitis C Membrane Viral glycoproteins                                  Hepatitis C Hepatocelullar carcinoma
                                                                                                       virus infection
                                                                              Chronic disease caused by hepatitis C virus infection           Closed Hepatitis C virus (HCV), the main cau
                             Illness     Qualitative research
Health Promotion Blood awareness prevention and health education                           HIV         Hepatitis C Injecting drug use
                                                                              Blood borne communicable diseases                               Closed This project will make a direct and m
                   Cholestatic hepatitis Hepatitis C Immunopathogenesis
Transplantation Immunology Gene Expression                 Virus       Liver Transplantation                                                         Closed Media Summary not available
                                recombinant baculovirus
Medical Virology antiviral agents           virus replication                                                           liver disease viral
                                                                                   cirrhosis hepatitis C hepatocellular carcinoma hepatitis          Closed HCV is a major cause of liver disease
Epidemiology                    Harm reduction
                   Blood-borne viruses Hepatitis Illict drugs Social determinants                                                                    Closed Media Summary not available
Hepatology                                   Virus        Oxidative stress
                                                                       Viral       Disease Hepatitis C related liver disease Therapeutic Closed The majority of individuals infected w
                   Gene ArrayHepatitis C Hepatocellular Carcinoma Pathogenesis pathogenesis Hepatocellular Carcinoma                                 Intervention,
                                                                                                                        Therapeutic Intervention, antioxidantsnew targets
Hepatology                                  hepatitis C
                   angiotensinhepatic fibrosis                                                 hepatitis C hepatocellular cancer primary biliary cirrhosis
                                                                                   hepatic fibrosis                     liver transplantation        Closed Hepatic fibrosis is a common respon
                                Development of chimeric virus-like particles (VLPs)
                                             foreign epitopes
Medical Virology Delivery of a variety of Induction of anti-HCV immune response                HCV: a major human pathogen inducing severevirus-like particles C virus (HCV) is a major ca
                                                                                                            Immunisation procedures based on Closed Hepatitis
                                                                                   Development of HCV vaccine                                         liver disease
                   diet
Nutrition and Dietetics         hepatitis obesity         steatosis treatment                                                                        Closed Media Summary not available
Infectious Diseases                         Risk factors
                   Hepatitis C Immune response                         Viral       Hepatitis
                                                          Transmission quasispecies C Incarceration         Injecting drug use                       Closed Hepatitis C (HCV) affects approximat
                   Attitudes/Behavior
                                Health
Social and Community Psychology Care experiences                                                                                                     Closed Media Summary not available
Public Health and Barriers to primary health care for Health providers settings people with hepatitis C
                   Health Services not elsewhere classified careHealth careDental careHepatitis C Injecting drug use
                                Discrimination by health carehealth for people injecting drugs
                                            Discrimination in with hepatitis C for
                                                          people         care                                           Nursing                      Closed
                                                                                                                                      Primary health care Hepatitis C is now the leading comm
Not Allocated                   hepatitis C risk practices
                   health outcomes homelessness young people                                                                                         Closed Media Summary not available
                                virus envelope protein Platform delivery
                                             virus                     Vaccine
Medical Virology Hepatitis B Hepatitis C Modified virus-like particles of foreign epitopes                                                           Closed Media Summary not available
                   (incl. Cell Division and Apoptosis) liver stem cells
                                inflammatory cytokines
Cell Development hepatocarcinogenesis liver regeneration                           alcohol     cancer                   v
                                                                                                            liver diseaseiral hepatitis              Closed Maintaining liver function is essential
Hepatology                      cellular immune response
                   acute infection          hepatitis C immunology     liver                                                                         Closed Media Summary not available
Gastroenterology HCV            HGV         HIV           Infect                                                                                     Closed Media Summary not available
                   Health Services not elsewhere service
                                            reproduction               women's health
Public Health and hepatitis C qualitative research classified utilisation                      drug
                                                                                   contraception addiction  hepatitis C                              Closed Hepatitis C is a growing health conce
                   Pathogenesis
Gastroenterology and Hepatology               function                             Chronic disease diseases hepatitis C virus infection
                                                                                                extracellular by
                                                                                                            cirrhosis
                                hepatic cellhepatology peptidases tissue remodelling andLiver caused matrix inflammation              liver fibrosis Closed Chronic liver diseases, particularly th
                                flavivirus                             fusion      flavivirus hepatitis C Virus infection
Medical Virology envelope glycoprotein hepatitis C membrane virus entry and replication                     virus                                    Closed Hepatitis C Virus infects approximate
                   Health Services not elsewhere safety
                                            injection international health
Public Health and Hepatitis C injecting drug use classified                                                                                          Closed Media Summary not available
                   Health       Blood-borne virus
                                            IDU
Public Health and BBV Services not elsewhere classified   prevention                                                                                 Closed Media Summary not available
                                            extracellular vitro and tissue of gene products
                                                                       liver disease
Gastroenterology Hepatitis C dipeptidyl pepidases inmatrixdefinciency remodelling                                                                    Closed Media Summary not available
                   Health Services
                                ethnography injecting drug use
                                                          public       s
Public Health and epidemiology not elsewhere classifiedhealthexual health          blood borne communicablecontextsexual healthoung people losed National drug surveys and surveillanc
                                                                                               injecting drug use
                                                                                                            risk diseases
                                                                                                                        s             y              C
                                hepacivirushepatitis viroporin virus replication
Medical Virology antiviral agents                                                                                       liver disease
                                                                                   cirrhosis hepatitis hepatocellular carcinoma                      Closed Hepatitis C virus is a major medical p
Epidemiology                    hepatitis C immune response
                   genetic testing                                      study
                                                          longitudinalviral persistence
                                                                                   epidemiology             hepatitis C virus infection persistence
                                                                                               genetic testing                        viral
                                                                                                                        immune responses             Closed The hepatitis C virus (HCV) is a majo
                   Health Services borne disease risk environment
                                blood       ethnography
Public Health and Vietnamese IDU not elsewhere classified                                                                                            Closed Media Summary not available
                   Health Services not elsewhere drug use medical      patient
Public Health and Hepatitis C adherence injecting classified treatment recruitment                                                                   Closed Media Summary not available
Immunogenetics MHC                          escape mutants
                                cytotoxic T lymphocytes                            HCV related pathogenesis
                                                                                               HLA typing               evasion of viral persistence
                                                          hepatitis C leucocyte membrane molecules disease progression the immune system             Closed Over 200,000 Australians are infecte
Medical Virology Hepatitis C                                                                                                                         Closed Media Summary not available
Epidemiology                     virus      injecting drug use
                   Hepatitis C drug treatment             pegylated interferon                                                                       Paying Media Summary not available
                   apoptosis hepatic fibrosis
Gastroenterology and Hepatology                           hepatocyte proliferation
                                            hepatic steatosis                      NAFLD                                obesity
                                                                                               hepatitis C nonalcoholic steatohepatitis              Closed Lay Description Fatty liver (steatosis)
Hepatology                                  hepatic steatosis
                   apoptosis hepatic fibrosis             hepatitis C hepatocyte proliferation                                                       Closed Media Summary not available
Hepatology                      Hepatitis C Pathogenesis of autoimmune cell biology fatty mechanisms of hepatic fi
                                             fibrotic injury
                                                          Pathogenesis of non-alcoholic and liver disorder
                   Hepatic ischaemia reperfusionprogression Stellatehepatitis                                                                        Closed In humans, chronic liver diseases cau
Endocrinology                   Insulin Restistance
                   Chronic Hepatitis C virusSteatosis body composition viral genotype                                                                Closed Media Summary not available
                                  viral sequences
Medical Virology Evolution ofImmune evasion               Viral glycoprotein function          Development of chronic HCV infection
                                                                                                            HCV
                                            Neutralizing antibody responses Ability to clear HCV infectioninfection                                  Closed Hepatitis C virus is a major human pa
                   elsewhere Clinical
                                classified H              Preclinical immunogenicity
Biotechnology not Cellular Immunity trials epititis C virus            Vaccines                                                                      Paying This research will advance the develo
Cellular Immunology             HIV vaccine development
                                            Hepatitis C InteractionsPharmacogenetics thedrug hypersensitivity reaction
                                                           disease       between HIV and of human host immune
                   Complications of antiretroviral drug therapypathogenesis                                                                          Paying The Centre for Clinical Immunology a
Medical Virology anti-viral chemokines                    interferon microarray
                                            hepatitis C virus                                                                                        Closed Media Summary not available
                  Cyp2e1
Gastroenterology and Hepatology             Hepatitis C virus replication
                               Hepatic Stellate Cells alcoholand anti-viral action of interferon expression fibrosis hepatitisiral replication
                                                                       oxidative stress
                                                                                    alcoholic liver disease hepatic
                                                                                                 gene                      viral       v             Closed Liver disease caused by alcohol cons
                                virus
Medical Virology Hepatitis C chemokines     gene expression
                                                          transcriptional regulation
                                                                       viral hepatitis
                                                                                    Hepatitis C hepatitis inflammation
                                                                                                  virus                    liver                     Closed The majority of individuals infected w
                  Chemokines epatitis C Inflammation
Infectious Diseases            H             virus        Liver                                  Hepatitis infection                                 C
                                                                                    Chronic liver injury C Inflammatory mediators and the liver losed The majority of patients who become
                  Health Services not injecting drug use  social
Public Health and Hepatitis C ethnicity elsewhere classifiedresearch   treatment                                                                     Closed Media Summary not available
Hepatology        Hepatitis C Liver disease               Obesity
                                            Metabolic syndrome Steatosis                                                                             Paying Media Summary not available
Hepatology                     Hepatic fibrosis            disease C Viral hepatitis
                  Chronic liver disease Hepatitis C Heptatis progression Chronic hepatitis C     Cirrhosis Hepatitis                                 Closed Hepatitis C virus (HCV) infection is a
                   elsewhere Diagnostic tests and toVaccine development, Diagnostic Assay
                               classified Immunity infection
Biotechnology not Antiviral, Viral Hepatitis; Virologyprocedures vaccine technology                                                                  Paying I am a virologist exploiting basic and
                               infectious disease
Medical Virology hepatitis C virus          liver                                                immune priming
                                                                                    cell mediated immunityimmune response                            Closed Most individuals who are infected wit
                               fusion       viral
Medical Virology membrane protein structureglycoproteins               virus receptors
                                                                                    Hepatitis C understanding virus-host interactions
                                                          virus entry and replication                        viral infection                         Closed Hepatitis C virus (HCV) infects appro
                               biochemical olecules tiggers
Medical Virology Cellular receptors         m                                                                                                        Paying Media Summary not available
                  Acute Hepatitis C infection
Cellular Immunology                         Immunopathogenesis
                               Cellular immunology Viral clearance                                                                                   Paying Media Summary not available
                               Membrane Viral glycoproteins
Medical Virology Hepatitus C Virus          fusion                                                                                                   Paying Media Summary not available
Medical Virology DNA vaccine                Virus-like particle C influenza Development
                                                          delivery                               Hepatitis C Infection influenza strategy
                                                                                                              and and Vaccine
                               Vaccine development, hepatitis of B-cell and CTL epitopes of hepatitis C B control vaccine                            Closed For the induction of good immune res
Medical Virology Antibodies Diagnostic Test                Virus Infection
                                            Hepatitis C Humoral Immunity            Antibody Diagnostic Assay                          Immune Response
                                                                                                             Hepatitis C Humoral Immunology Closed The prevalence of Hepatitis C in Aus
                  dendritic cell targeting synthetic lipopeptides
Infectious Diseases            epitope mapping                                                               vaccine
                                                          vaccine development hepatitis C infectious diseases development  viral immunity            Closed The parts of viruses, bacteria and of
                  acute hepatitis, chronicclinical care of personC; hepatitis B; C
Infectious Diseases                           hepatitis Cheapatitis with hepatitis HIV-AIDS; therapy
                               chronic hepatitis B; HIV                                                                                              Paying I am infectious disease physician und
Hepatology                     hepatic
                  ductular reaction fibrosishepatic progenitor cells                             fatty liver hemochromatosis insulin resistance
                                                                                    chronic liver disease disease          hepatic     hepatitis C Closed Chronic liver diseases such as hepat
                  CD8+ T lymphocytes Tolerance Transgenic Transplantation
Cellular Immunology            Liver                                    mice        Hepatocarcinomas
                                                                                                 autoimmune and viral Hepatitis
                                                                                                                           transplantation
                                                                                                             liver autoimmune diseases               Closed The liver has paradoxical properties:
Medical Virology Antiviral Gene Expression                 Virus                                  Virus      interferon therapy HCV
                                            Hepatitis C Interferon microarray Hepatitis C Host antiviral responseliver disease                       Paying The only treatment for hepatitis C is I
                  Vaccine classified by hepatitis
                               caused       diseases,infection control,chronic disease infectious
                                                          hepatitis,influenza,reproduction,
Immunology not elsewheredevelopment,antigen presentation,viral                                                                                       Paying I am an immunologist with a backgro
                  Cellular immunology Genetics Hepatitis C Neuroimaging
Infectious Diseases            Chronic fatigue syndrome                                                                                              Paying I am a clinician-scientist studying the
                  Health Services not elsewhere classified determinants of health
Public Health and Public health             Risk behaviour
                               Qualitative research Social                                                                                           Paying This project seeks to discover how an
Epidemiology                   immune response
                  hepatitis C virus                       proteasomes  statistics
                                            population genetics and evolution                                                                        Paying Two hundred million people are infec
Hepatology                     hepatitis c insulin resistance
                  antiviral therapy                       interferon signaling
                                                                       obesity                               interferon - obesity treatment
                                                                                    hepatitis c insulin resistance         ribavirin                 Paying The development of vaccines and be
Hepatology                                  Lifestyle Liver
                  Cytokine Insulin resistance factors                  Obesity      Hepatic insulin resistance
                                                                                                 Hepatitis C exercise trainingliver disease
                                                                                                                           fatty                     Paying
                                                                                                                                       obesity-metabolism The overall objective of this Research
                  Alcohol abuse and dependance
                               Alcoholic liver
                                            Clinical care of persons Alcohol C, Injecting drug use
                                                                       Hepatitis
Clinical Sciences not elsewhere classified disease Drug abuse, with hepatitis C                                                                      Paying The two most common types of liver
Hepatology                     hepatitis
                  exercise physiology c insulin resistanceobesity      pathogenesis                                                                  Paying I am a gastroenterologist investigatin
                  Cell mediated immunity
Gastroenterology and Hepatology                           Viral Immunology
                               Hepatitis C Liver transplantation                    Chronic disease caused by hepatitis C virus infection hepatocellularChronic hepatitis C (CHC) infection a
                                                                                                 Cirrhosis Liver diseases transplantation
                                                                                                                           Liver       Primary       Paying  carcinoma
Hepatology                     inflammatory cytokines
                                            liver cell lineage commitment
                                                                       stem cells
                  hepatocytes and cholangiocytes liver progenitor cells cell therapychronic liver disease    viral hepatitis, HBV and HCV            Paying Liver diseases associated with Hepa
                                                          Stem cells
Gastroenterology Hepatitis B Hepatitis C Liver progenitor cells Tissue regeneration                                                                  Closed Liver disease is a serious health prob
                  hepatitis C humoral immunology vaccine development
Infectious Diseases                         immune response            virus like particle                                                           Paying The infection rate of HBV is 20% in C
                  HIV-AIDS Hepatitis C immune response
Infectious Diseases                                       immunity vaccines                                                                          Paying There is an urgent need to develop th
                                             Virus        viral fusion
Medical Virology Antibody Hepatitis C envelope glycoprotein                         acute hepatitis
                                                                                                 chronic disease caused by hepatitis C virus infection
                                                                                                             development of HCV vaccine
                                                                                                                           prevention of infectious disease The first stage of Hepatitis C Virus re
                                                                                                                                       viral hepatitis
                                                                                                                                                     Paying
                  Fc
Infectious Diseases Receptors  HIV-AIDS NK cells macrophages                                     HIV         Hepatitis                 immune dysfunction
                                                                                                                                                     Paying
                                                                       monocytes HAART-AIDS pathogenesis C Immune Reconstitution Disease This project will determine how viruse
                               infectious disease
Medical Virology hepatitis C virus          liver                                                immune response.
                                                                                    cell mediated immunityneutralising antibody                      Paying A successful vaccine for RNA viruses
                  hepatitis C virus
Gastroenterology and Hepatology             liver
                               infectious disease       therapy                  cell mediated immunity
                                                                                             cell therapyimmune response.          antibody     Paying It is possible to cure some patients w
                                                                                                                     neutralising viral clearance
Gastroenterology and Hepatology
                  cirrhosis genetic polymorphismspharmacogenomics
                                            hepatitis C                                                                                         Paying Chronic hepatitis C infection (CHC) c
                  Cellular immunity C virus immunity
Cellular Immunology            Hepatits Innate                                                                                                  Paying Hepatitis C virus (HCV) poses a majo
Epidemiology                                molecular epidemiology
                                                        sexual
                  hepatitis C men who have sex with men transmission acute hepatitis C       hepatitis C sexually transmitted infections        Paying Hepatitis C virus (HCV) is usually tran
                  Aboriginal health
                               Sexually transmitted infections
Clinical Sciences not elsewhere classified  Viral hepatitis                                                                                     Paying This proposed new CCRE will bring t
                  Addiction Health outcomes policy and services evaluation
Health and Community Services               Health      Hepatitis C Opioid dependence                                                           Paying Hepatitis C (HCV) treatment uptake r
                  Health Services not elsewhere classified population
                                Australians             prison
Public Health and Indigenous hepatitis C mathematical modelling     qualitative research Health hepatitis C delivery health issue
                                                                                 Aboriginal chronic      service infection
                                                                                                                     social                     Paying Despite the availability of an effective
                               virus entry and replication
Medical Virology viral glycoproteins        virus receptors                                  Hepatitis C Virus replication
                                                                                 Chronic infection                                              Paying Hepatitis C Virus infects 3% of the wo
Epidemiology      cohort studies
                               injecting drug use
                                            molecular epidemiology epidemiology
                                                        social netword hepatitis
                                                                    viral                                                                       Paying The new influenza A (H1N1) outbrea
                  Health Services use health servcie utilisation
                               drug not                 risk behaviour hepatitis
Public Health and Prison populations elsewhere classified           viral                                                                       Paying Hepatitis C is is a leading cause of liv
                               Infectious Diseases
                                            Innate Immunity
Medical Virology Chronic hepatitis C virus infection Interferon Virus Replication                                                               Paying I am a molecular virologist researchin
                  Hepatic Fibrosis
Gastroenterology and Hepatology                          Apoptosis Liver Transplantation
                               Hepatitis C HepatocyteImmunosuppression                                                                          Paying Mast cells are important in immunity.
                  Economic evaluation Health policy and services evaluationmodelling disease Health services
Health and Community Services  Health outcomes          Hepatitis C Mathematical Chronic liver
                                                                                             Health outcomes                       Population health
                                                                                                                     Hepatitis C virus infectionPaying To evaluate the impact of introducing
                  Health Services
                               hepatitis elsewhere drug use
Public Health and cohort studies not C injecting classified
                                                        randomised controlled development of HCV vaccine drug use
                                                                    vaccine preparedness hepatitis C injecting liver disease
                                                                                 trial       studies                                            Paying Injecting
                                                                                                                                   prevention of infectious diseasedrug users (IDU) are a key t
Medical Virology Chronic Infection of the immunevirus infection
                               evasion      hepatitis C system                                                                                  Paying Hepatitis C virus (HCV), a major caus
                  Health Services
                               Infectious diseases drug use
                                            Injecting Population health
Public Health and Epidemiology not elsewhere classified             Vaccines                                                                    Paying GSAO is an Australian anti-cancer dr
                  Chronic viral infectionsHCV
Infectious Diseases            HBV                      Herpes viruses                                                                          Paying HIV, Hepatitis B and Hepatitis C are m
Innate Immunity vaccine biology             cytokine production hepatitis C infection vaccine technology
                               dendritic cell           bone marrow              adjuvant                            dendritic cell epatitis C infection Dendritic cells (DC) are rare cells tha
                                                                                                         viral immunity            h            Paying
                  liver diseaseepatitis C infection antiviral agents
Gastroenterology and Hepatologyh            hepatic steatosis       cannabis liver diseaseepatitis C infectionsteatosis therapy
                                                                                             h           hepatic     antiviral                  Paying Hormones related to cannabis help to
                  liver         not elsewhere classified
                                            lifestyle
Medical and Health Sciences hepatitis C infectionfactorsmetabolic syndrome disease C virus liver disease
                                                                    fatty liver hepatitis fatty          fibrosis    lifestyle factors          Paying The overall objective of my research
                  hepatitis C virus resistance
Infectious Diseases            drug         sequencing                                       drug therapy
                                                                                 hepatitis C infection resistance                               Paying Hepatitis C therapy in the future is lik
                               human        chronic infection
                                                        T cells
Medical Virology virus pathogenesisimmunodeficiency virus (HIV)     cytokines chronic infection immunodeficiency virus (HIV)
                                                                                             human                   hepatitis     hepatitis
                                                                                                         virus pathogenesis B infection C virus Paying Our robust ability to mount an immun
                  hepatology hepatitis C infection interferon (IFN) efficacy diseaseepatitis C infection (IFN)
Gastroenterology and Hepatology             liver disease           drug         liver       h           interferon genetics                    Paying About 3% of the world population is c
Biostatistics                                studies                drug
                  biostatisticsassociationgenomics vaccine design resistance                 hepatitis C virus immunodeficiency virus (HIV)
                                                                                                         human
                                                                                 human leukocyte antigen (HLA)                                  Paying Viruses such as HIV or Hepatitis B or
                  hepatitis C infection B infection prevention health services research
Health and Community Services  hepatitis prison population                                   hepatitis injecting liver disease
                                                                                 hepatitis C infection B infection drug use                     Paying Hepatitis B and C infection rates rem
                  clinical research
Gastroenterology and Hepatology                                                              prognosis               treatment complications aying Patients undergoing treatment for he
                               genomics proteomics translational research hepatitis C infection pharmacogenomics outcomes                       P
                               chronic infection
                                            therapeutic target
Medical Virology human immunodeficiency virus (HIV)                              chronic infection immunodeficiency virus (HIV)
                                                                                             human                   hepatitis     hepatitis
                                                                                                         immune modulation B infection C virus  Paying Chronic infections produced by patho
                  hepatitis C virus immunodeficiency virus (HIV) diseases
Infectious Diseases            human                    virology
                                            blood-borne communicable             hepatitis C virus immunodeficiency virus (HIV) diseases
                                                                                             human       blood-borne communicable
                                                                                                                     virology                   Paying Hepatitis C affects between 1-3% of
Immunogenetics (incl. Genetic Immunology) polymorphism (SNP)
                  hepatitis C infection interferon (IFN)
                               single nucleotide                                 hepatitis C infection non-responders
                                                                                             interferon interferon (IFN)                        Paying An estimated 3% of the world’s popu
                               glycoproteins
Medical Virology hepatitis C virus                                  receptor binding         vaccine
                                            antibody vaccine development chronic infection design        structure-function                     Paying Hepatitis C Virus infects 200 million p
                  viral immunity clearance
                                 not
Biochemistry and Cell Biologyviral elsewhere classified
                                            innate immunity
                                                        microrna interferon (IFN)dengue virus            hepatitis C virus
                                                                                             influenza virus                                    Paying microRNAs (miRNAs) constitute a no
                               hepatitis prevention injecting drug use
Health Promotion qualitative research C virus                       relationships                                                               Accepted Transmission of hepatitis C among p
                               antiviral agents pathogenesis
Medical Virology hepatitis C virus          virus                   hepatitis C infection
                                                                                 liver
                                                        host/pathogen interaction disease                                                       Paying Hepatitis C virus (HCV) is a serious v
                  hepatitis C infection hepatitis C virus
Infectious Diseases            clinical research        epidemiologyhealth services research                                                    Paying The renewal of my Practitioner Fellow
                  hepatitis C virus
                               liver
Gastroenterology and Hepatology injury obesity          inflammationadiposity                                                                   Accepted Presently, liver disease from chronic
                  Health Services
                               injecting elsewhere classified
                                            natural
Public Health and hepatitis C virus not drug use history                         epidemiology
                                                        treatment access to health care                                                         Accepted In Australia, the majority of hepatitis C
                            hepatocellular
                                       hepatoma                        cancer
Cancer Diagnosishepatocellular carcinoma cancer liver cancercancer detection screening genetics fibrosis
                                                                                 cancer   liver                     hepatitis    Accepted
                                                                                                       hepatitis C infection B infection Hepatocellular carcinoma (HCC) is th
                interferon-alpha (IFN-alpha)
                            hepatitis hepatitis innate immunity
Immunology not elsewhere classified B infection C infection immune response                                                      Accepted Despite recent advances in therapeu
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  to evaluate the efficiency of a virus-like particle (VLP) vaccine for hepatitis C virus (HCV). HCV infects about 10,000 people every year in Australia and approximately 8, 000 of these will develop p
es are the agents of many mosquito-transmitted infections such as encephalitis and dengue, and hepatitis C virus is a member of the same virus family. During virus multiplication in cells, new mem
 tis C virus (HCV) continues to spread among injecting drug users (IDUs) in Australia at a very high rate, despite success in preventing the spread of HIV in the same groups; the complete reasons
 will identify the health and social support needs of men who are infected with hepatitis C and will complement a similar study currently being conducted with women. At present, there is little inform
 er diseases, particularly those caused by Hepatitis B virus and Hepatitis C virus infection, are major causes of morbidity and mortality in our community. They are characterised by progressive sca
 nce of hepatitis C virus (HCV) infection is rapidly increasing in our community. This infection cannot be prevented by vaccination and the current treatments often fail. We believe that the novel ap
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 s causing hepatitis in man must cross specialised cell layers in the body to reach the liver, and must again cross these cell layers and liver cells in order to be transmitted to subsequent hosts. Thi
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C virus (HCV), the main cause of of post-transfusion and community -acquired non-A, non-B hepatitis, infects approximately 170 million humans world-wide with some 135,000 infections in Austral
ct will make a direct and major contribution to Hepatitis C prevention by addressing the need for blood awareness in prevention education. The need for measures to prevent the spread of HCV is
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major cause of liver disease and around 200 million people are currently infected worldwide, including 200,000 Australians. HCV differs to other flaviviruses. Most notably, around 80% of individual
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 ty of individuals infected with hepatitis C virus (HCV) show a slow progression of liver disease over a period of 20-30 years. There is increased scaring of the liver which can result in liver failure a
 rosis is a common response to chronic liver injury, during which the normal liver architecture is distorted by scar tissue. Hepatic fibrosis can lead to cirrhosis and liver transplantation may be requi
C virus (HCV) is a major causative agent of chronic liver disease and occurs in about 1% of the world's population. HCV is a quasispecies characterised by sequence variations and the rise of imm
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C (HCV) affects approximately 200,000 Australians, of whom a significant minority develop long term complications, including cirrhosis, liver failure and liver cancer. The dominant mode of transmi
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C is now the leading communicable disease in Australia and stigma and discrimination have been identified as major barriers to addressing this epidemic. This study builds on our previous work in
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 g liver function is essential for health, and compromising this ultimately results in death. The liver is unusual, as it can regenerate to replace lost or damaged tissue. Recently it has been establishe
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C is a growing health concern, with 1% of the Australian population now HCV positive, and signs that it is increasing more quickly among women of child-bearing age. This study builds upon recent
 er diseases, particularly those caused by autoimmune disease, alcohol and Hepatitis B and C virus infection, are major causes of morbidity and mortality in our community. They are characterised
C Virus infects approximately 200 million people world-wide and is the major cause of liver transplantation in the Western world. At present there is no vaccine and interferon alpha is the only thera
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rug surveys and surveillance systems have detected sharp increases in the use of 'psychostimulant' drugs such as the amphetamines, ecstasy and cocaine. The level of harms associated with ex
C virus is a major medical problem in Australia and many other parts of the world. The viruses causes a persistent infection in most infected individuals that results in serious liver disease and liver
 tis C virus (HCV) is a major public health problem affecting over 170 million people worldwide. In Australia an estimated 157,000 people have HCV and are at risk of serious disease, and 16,000 n
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000 Australians are infected with the Hepatitis C Virus (HCV) and about 11,000 new infections are diagnosed each year. Around 25% of people infected with HCV will clear the virus while for indivi
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 ption Fatty liver (steatosis) is important because it increases the vulnerability of the liver to factors that trigger inflammation and fibrosis. Patients with steatosis may develop steatohepatitis sponta
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 , chronic liver diseases cause cirrhosis of the liver in some but not all individuals. This leads to protracted ill-health, complications (fluid retention in the abdomen, confusion, bloodstream infections
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C virus is a major human pathogen infecting 200 million people world-wide. Currently, there is no vaccine to prevent infection and treatment regimes are only partially effective. IInitial HCV infection
 rch will advance the development of a novel vaccine strategy based on duck hepatitis B virus-like particles (VLPs). These VLPs can be engineered to contain parts of other viruses such as Hepati
e for Clinical Immunology and Biomedical Statistics (CCIBS) represents a collaboration between Royal Perth Hospital and Murdoch University that has brought together internationally recognised e
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ase caused by alcohol consumption and hepatitis C virus (HCV) infection are major national health problems. Liver disease caused by HCV is greatly accelerated by alcohol consumption, however
  ty of individuals infected with hepatitis C virus (HCV) show a slow progression of liver disease over a period of 10-20 years. This liver disease is primarily a result of the host immune response to l
  ty of patients who become infected with hepatitis C virus (HCV) are unable to mount an effective immune response and clear the virus and therefore develop lifelong (chronic) infection. The persis
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C virus (HCV) infection is a major cause of liver disease and associated deaths in Australia. HCV infection leads to progressive liver failure and may be associated with the development of liver can
  logist exploiting basic and applied research on hepatitis viruses to develop biotechnology innovations in diagnostics and vaccines for a broad range of infectious diseases
  duals who are infected with hepatitis C virus (HCV) develop a persistent infection that is lifelong and are at risk of developing serious liver disease, including liver cancer. The evidence suggests th
C virus (HCV) infects approximately 3 % of the global human population with 150,000-200,000 HCV-infected individuals currently living in Australia. Chronic HCV infection is associated with recurre
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duction of good immune responses, antigens should be delivered in several copies on a defined particle. The small envelope protein (HBsAg) encoded by the hepatitis B virus (HBV) has the capac
  ence of Hepatitis C in Australia has been estimated at 242 000 people with 80% of infections acquired as a result of infection drug use. The currently available assays can be used to reliably dete
 of viruses, bacteria and of cancer cells that are recognised by the immune system are called epitopes. Epitopes are generated from these agents by dendritic cells which are found in many parts o
 ious disease physician undertaking research on natural history and therapeutic strategies in viral hepatitis, including acute hepatitis C, chronic hepatitis C and chronic hepatitis B. The hepatitis C t
  er diseases such as hepatitis C and obesity-related fatty liver can be associated with scarring that eventually results in cirrhosis and liver failure. We are unsure why this scarring occurs, but as he
  as paradoxical properties: it is the site of effective immune responses to pathogens, but under some circumstances, it is known to induce harmless immune responses. Poor responses can be be
  eatment for hepatitis C is Interferon-ribavirin combination therapy. Interferon works by stimulating the liver cells to produce antiviral proteins that can control hepatitis C virus replication, however w
  munologist with a background in virology and peptide chemistry and my work is therefore inter-disciplinary but focused on the design of synthetic, epitope-based vaccines against infectious agents
 ician-scientist studying the biological determinants of clinical outcomes in infectious diseases.
ct seeks to discover how and why some injecting drug users have managed to avoid becoming infected with hepatitis C despite having injected for many years in localities in which most other injec
  ed million people are infected with the Hepatitis C virus. There is no vaccine and the rate at which new strains of the virus arise enable it to evade the human immune system. This study aims to d
opment of vaccines and better treatments for HIV-AIDS and Hepatitis C are urgent global health priorities. This Program will undertake studies to better understand effective immunity against HIV
  l objective of this Research Project is to examine the mechanisms by which obesity and fatty liver impair the response to antiviral treatment in patients with chronic hepatitis C and to develop spec
 ost common types of liver disease in Australia are chronic hepatitis C (Hep C) and fatty liver disease and both result in more severe liver injury when the person is overweight. We propose to test
  troenterologist investigating novel treatment approaches for substance abuse problems, particularly involving the gastrointestinal system
epatitis C (CHC) infection and obesity are conditions of increasing prevalence. Untreated, CHC has significant long-term consequences including cirrhosis and liver failure, while obesity reduces th
ases associated with Hepatitis C, including liver failure and liver cancer, are now the leading indication for liver transplantation globally. However, the virus re-infects the new liver and eventually re
ase is a serious health problem. Viral hepatitis, obesity and alcohol can result in end-stage liver disease. Organ transplant is the only treatment available. A widening gap between organ donations
 on rate of HBV is 20% in Chinese and 10% in Australian in particularly aboriginal. The end-point of this disease is development liver failure and need functional replacement of the liver. Cell therap
n urgent need to develop therapies for treating and preventing Hepatitis B antiviral resistance, particularly in patients with advanced liver disease. Investigator-initiated clinical studies will be perfor
  age of Hepatitis C Virus replication involves attaching to liver cells. This study is aimed at understanding how the virus attaches to liver cells and how antibodies raised during infection, block this i
ct will determine how viruses prevent transmission of messages within cells which orchestrate responses of our immune system to infection and whether our current therapies improve this defect.
 ful vaccine for RNA viruses like HIV and hepatitis C (HCV) will require cell mediated immunity (CMI) as well as neutralising antibody. The vaccine delivery vehicles which are currently in use to gen
  le to cure some patients with HCV infection but the current therapy is very costly and produces numerous side effects in treated individuals. We propose to treat patients using a new therapy in wh
epatitis C infection (CHC) causes liver failure, liver cancer and death. The treatment response rate is poor. Understanding of the factors that increase an individual’s risk of developing serious liver
C virus (HCV) poses a major public health problem with ~200 million people infected worldwide and no available vaccine. Injecting drug users (IDUs) are the major risk group, with 75% of infected
C virus (HCV) is usually transmitted by blood-to-blood contact. The risk of transmission by sexual contact has been thought to be low. However, in recent years increasing hepatitis C infection has
  sed new CCRE will bring together the leading Australian institution dedicated to clinical research on sexually transmitted and blood borne viral infections, and the peak organisation for Aboriginal C
C (HCV) treatment uptake remains extremely low in Australia (2% of 204,000 people with chronic HCV per year). Barriers to HCV treatment are greatest among recovering and current injecting dru
 e availability of an effective treatment for hepatitis C and the high prevalence of infection among Australian prisoners treatment uptake is extremely low. Using survey data and qualitative interview
C Virus infects 3% of the world's population causing recurring liver disease, cirrhosis and hepatocellular carcinoma. To infect a liver cell, the viral glycoproteins attach to cell surface molecules whe
nfluenza A (H1N1) outbreak in Australia occurred at the start of the southern hemisphere flu season. The large numbers of cases in Victoria places us in a unique position to examine the epidemio
C is is a leading cause of liver transplants, and affects an estimated 180 million people worldwide, representing an increasing burden to the health system. This PhD focuses on how hepatitis C is t
  ecular virologist researching the host response to hepatitis C virus (HCV) infection with the aim of understanding how the liver clears HCV infection. An understanding of this process will hopefully
  are important in immunity. Mast cells have been implicated in asthma and more recently they have been shown to participate in immunity against bacteria, viruses and fungi. We have identified a
  e the impact of introducing hepatitis C virus (HCV) prevention and treatment strategies on the burden of hepatitis C in Australia through mathematical transmission models and health economics a
 rug users (IDU) are a key target group for new vaccines designed to prevent hepatitis C virus (HCV) infection. This study will establish the feasibility of conducting HCV vaccine trials in IDUs by an
C virus (HCV), a major cause of hepatitis and liver failure is a very significant global problem with approximately 3% of the world’s population infected and the rate of new cases increasing rapidly. T
  n Australian anti-cancer drug that is currently being trialed in cancer patients. It is a mitochondrial poison that stops tumours from making blood vessels, which they need to grow and spread. GSA
 titis B and Hepatitis C are major health issues, especially to indigenous people. Finding effective cures is a global priority. Current therapy is expensive and fails to cure these diseases. Our resear
  ells (DC) are rare cells that are crucial in response to infection and surveillance of damaged tissues. We aim to understand the tools that are expressed by DC that allow them to sense pathogens
   related to cannabis help to regulate fat stores in the human body. CB1 antagonists are a new class of drugs that block these hormones and are being tested for the treatment of obesity and fatty l
  l objective of my research activity is to examine in human subjects, the mechanisms by which obesity and fatty liver impair the response of the liver to injury and inflammation from multiple causes
C therapy in the future is likely to involve the use of Directly Acting Antivirals, which offer a better chance of treatment success and shorter treatment courses. The downside to these new agents is
t ability to mount an immune response and clear infections is tempered by the possibility of promoting autoimmunity. Several host genes regulate immunity. Viruses like HIV have exploited these to
 of the world population is currently infected with hepatitis C virus (HCV). Most have chronic infection with a high risk for progressive liver fibrosis and subsequent liver cirrhosis and hepatocellular
  ch as HIV or Hepatitis B or C may escape detection, and hence control, by the human host immune system through strategic mutations. This project aims to develop statistical methodologies whi
B and C infection rates remain very high in some Australian populations, notably prisoners. As this group cycles frequently back to the general community, prevention of transmission is critical. An
ndergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic p
 fections produced by pathogens such as HIV, overwhelm our immune system leading to an exhausted state where cells responsible for the clearance of invading microorganisms are unable to res
C affects between 1-3% of Australians. Currently, there is no effective vaccine and only 30% will spontaneously clear infection, while the remained develop a chronic disease with a small risk of pro
  ed 3% of the world’s population is infected with hepatitis C virus (HCV). With low spontaneous clearance rates and often a poor response to treatment many infected individuals will develop long t
C Virus infects 200 million people world-wide with over 200,000 Australians infected with the disease. This project will examine how the surface proteins of HCV change their shape to evade antibo
 s (miRNAs) constitute a novel mechanism used by cells and viruses to regulate gene expression. Studies carried out in non-human primates demonstrated great potential for miRNA-inhibiting dru
 ion of hepatitis C among people who inject drugs occurs primarily as a result of sharing of equipment used to inject drugs, the majority of which occurs between intimate couples. However, there is
C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathw
  al of my Practitioner Fellowship will continue to facilitate an expanding program of epidemiological and clinical research in viral hepatitis, with a primary focus on hepatitis C. New directions will inc
  liver disease from chronic hepatitis C and obesity represents a major health problem. Overall, approximately 50% of Australians with chronic hepatitis C are obese and these patients are at signifi
a, the majority of hepatitis C is acquired by injecting drug users (IDUs). Given the asymptomatic nature of infection and difficulties in identifying and following those at risk of acquiring infection, our
ular carcinoma (HCC) is the most common primary liver cancer and worldwide is the third and fifth leading cause of cancer death in men and women respectively. Early diagnosis is vital to patien
cent advances in therapeutic options, chronic viral infections, including infection with hepatitis C virus and hepatitis B virus, continue to be a significant cause of morbidity and mortality in Australia
00 of these will develop persistent infection. As a result, there are currently 150,000-200,000 HCV carriers in Australia and 500 million worldwide. These individuals represent a source of infection.
  ication in cells, new membrane structures are induced and these represent regions where the replication events occur. Using Kunjin virus, an agent of Australian encephalitis, as a model, and adv
ps; the complete reasons for this remain unclear. There is an urgent need for the HCV epidemic among IDUs to be contained. To do so, we must better understand the ways in which it is spreading
esent, there is little information about the ways that hepatitis C impacts on the lives of men and research on the impact of related diseases (HIV-AIDS) strongly suggests that hepatitis C is likely to a
 rised by progressive scarring of the liver which finally leads to liver failure and the need in many cases for organ transplantation. We have identified a key molecule Fibroblast Activation Protein (FA
believe that the novel approaches we are taking towards gaining an improved understanding of this disease process have the potential to lead to better therapies. We propose to examine disease

o subsequent hosts. This research will examine how each of the hepatitis viruses (HAV to HEV) are able to enter and exit the body, and the role that these mechanisms may play in the developme

000 infections in Australia alone. HCV is hyper-endemic in intravenous blood users with typical prevalence rates of 60-70%. About 75-80% of infected individuals develop a chronic infection, usua
nt the spread of HCV is based on the clinical implications of infection combined with its current prevalence and predicted spread within Australia. More than 200,000 Australians are estimated to b
around 80% of individuals develop a persistent infection, accounting for the large number of carriers. This infection is probably life-long and 40-50% of carriers will develop serious liver disease, inc

an result in liver failure and in some individuals liver cancer. Due to the lack of suitable model systems to study HCV infection and disease progression there is no currently available vaccine and tr
 plantation may be required for patients with liver failure and hepatocellular carcinoma. The chronic liver injury may result from a number of causes including alcohol, persistent viral infections and
 ions and the rise of immune escape mutants. No vaccine is available, hence there is an urgent need for prevention of infection and for effective treatment. No animal model exists with the exceptio

minant mode of transmission of this virus is via blood-to-blood contact, particularly via injecting drug use. Prisons appear to be a key focus of transmission of hepatitis C in the community as the m

 on our previous work in which we have found evidence of discrimination against people with hepatitis C in health care settings. Discrimination, inappropriate and unfair treatment against people w


tly it has been established that there are two pathways to liver regeneration. One involves hepatocytes, and this is normally associated with acute liver damage. The other, involves liver progenitor


study builds upon recent research that shows that Australia women with Hepatitis C have low levels of contraception even though they have specific contraceptive needs relating to concerns abou
. They are characterised by progressive scarring of the liver which finally leads to liver failure and the need in many cases for organ transplantation. Each year 15,000 Australians become infected
n alpha is the only therapy available and has only limited success in clearing viral infection. HCV is distantly related to flaviviruses eg tick-borne encephaltitis virus and yellow fever virus. All viruse



arms associated with excessive use of these drugs, such as mental health problems and drug dependence, has also increased, as has the use of these drugs via injection. These increases in the
 s liver disease and liver cancer in a proportion of patients. Treatment is only possible for a small percentage of patients and many patients are infected with viruses which are resistant to the best
us disease, and 16,000 new infections occur each year. Treating HCV-related disease is expensive, and this healthcare burden is projected to grow significantly in coming years. Almost all new HC


 the virus while for individuals with chronic infection 10 to 20% will develop cirrhosis of the liver within the next 20-40 years. Differences in host genetic factors and viral variants will, in large part, e


p steatohepatitis spontaneously and this increases the risk and rate of progression to cirrhosis, with consequent liver-related morbidity and mortality. In addition, steatosis significantly potentiates t

n, bloodstream infections, kidney failure, liver cancer) resulting in hospitalisation, liver transplantation and premature death. In Australia, cirrhosis is an important cause of death and of years of pot

 ve. IInitial HCV infection is frequently asymptomatic and 30% of people spontaneously clear the virus. The remaining 70% of people develop a life-long chronic infection that causes progressive liv
r viruses such as Hepatitis C, HIV or Measles, and have been shown to produce strong antibody responses in mice. Detailed information on the cellular and antibody responses to these VLP vacc
ernationally recognised expertise in clinical immunology, experimental biology and innovation in biostatistics and computing. These resources have been applied to a broad range of research issue
ol consumption, however, the connection between the biochemical events initiated by alcohol, HCV and inflammatory pathways resulting in liver disease are not well understood. Preliminary studie
st immune response to liver cells (hepatocytes) infected with HCV. As part of this immune response there in an increase in the number of immune cells that infiltrate the liver. To date we do not ful
 nic) infection. The persistence of virus in the liver of patients with chronic infection results in the recruitment of significant numbers of immune cells, notably T cells, from the bloodstream into the li


 development of liver cancer. Currently there are an estimated 220,000 people in Australia living with HCV infection, and by 2020 it is estimated that this number will treble. There is now considerab

The evidence suggests that an inadequate immune response is responsible for the inability of the patient to resolve the infection, but it is not clear which stage of the immunological cascade might
s associated with recurrent, progressively worsening liver disease, liver cirrhosis and hepatocellular carcinoma. The current therapy (interferon-ribavirin) is effective in only 40 % of patients and is o



rus (HBV) has the capacity to self-assemble with host derived lipids into VLPs. HBsAg VLPs are the sole component of one of the most successful vaccines, and clinical trials have shown that they
  be used to reliably determine the prevalence of Hepatitis C infection but provide no information regarding the incidence of infection. By thoroughly investigating the immune response generated by
 re found in many parts of the body where they act as sentinels on the look out for dangerous organisms. Epitopes are very small pieces of the proteins against which immune responses are moun
atitis B. The hepatitis C therapeutic research has a particular focus
carring occurs, but as hepatitis and fatty liver are becoming more common it is necessary to understand this process so that effective therapies can be developed. This study looks at one possible
 or responses can be beneficial in a transplantation setting because, in the absence of immunosuppressive drugs, liver transplants are more readily accepted than other organ allografts. Not only a
us replication, however we do not know which proteins are responsible. The aim of this proposal is to identify those proteins that can limit HCV replication using both a laboratory based and clinical
against infectious agents particularly influenza and hepatitis C viruses an

in which most other injectors have acquired the virus. The primary interest is on the strategies used by current long term (8 years or more) injectors to avoid HCV infection. Research will also be d
em. This study aims to decipher how new viral strains are generated and transmitted, thereby enabling the development of new vaccines.
e immunity against HIV and hepatitis C, allowing the rational design and testing of novel vaccines and treatments. The Program brings together a team of researchers with skills in basic virology a
s C and to develop specific strategies to monitor and improve the outcome of treatment. In addition, the development of non-invasive strategies and surrogate cell culture systems for the assessm
ght. We propose to test if weight loss through lifestyle changes such as improving diet or increasing exercise are suitable treatment alternatives for people living with liver disease. This will help do

 while obesity reduces the success of antiviral treatment. A tendency to develop diabetes in patients with CHC and obesity also leads to further medical complications. We aim to examine the effec
w liver and eventually results in scarring and liver failure. This work aims to understand the role of the immune response to the virus in this liver damage, thus allowing modification of existing treat
etween organ donations and recipients mandates alternative treatments are developed. Cell transplantation and artificial liver devices are alternatives which can use liver progenitor cells. We will i
nt of the liver. Cell therapy represents an alternative of liver transplantation owing to shortage of organ. The information derived from this study is essential for developing strategies to promote gro
cal studies will be performed to examine a) the most effective therapy for preventing antiviral resistance and Hepatitis B recurrence following liver transplantation and b) the effect of a novel Hepati
ing infection, block this interaction. In addition, this study aims to examine how the virus modulates its structure to evade the immne system, allowing the virus to establish chronic infections. The r
 ies improve this defect. This knowledge will help us to better understand why our immune system is not able to control chronic virus infection and improve therapies for these diseases.
re currently in use to generate CMI are not effective because individuals have pre-existing immunity to the delivery vehicle or generate immunity to the vehicle in a multiple dose regimen. This proj
 sing a new therapy in which HCV proteins are first expressed in blood cells ex vivo and the cells then manipulated to generate dying cells. These will be injected into the same patient from which th
 developing serious liver disease, or that lead to treatment failure, is limited. This project, the first of its kind, will involve screening 1600 CHC patients for genes that are associated with disease ou
up, with 75% of infected individuals progress to chronic infection, which can then lead to liver cirrhosis and hepatocellular carcinoma. However, about 20% of a given cohort of IDUs remains uninfe
  epatitis C infection has been documented among HIV-positive gay men, with sexual contact the most most likely means of infection in the majority of cases. This grant will use established cohorts
 anisation for Aboriginal Community Controlled Health Services. Working with nominated Aboriginal community controlled health services, the Centre will conduct innovative research that will ident
 and current injecting drug users. A large proportion of this population is receiving opiate pharmacotherapy, but few HCV treatment services have been developed in this context. The goal of this pr
 and qualitative interviews with prisoners and prison health staff this project will investigate the structural and cultural barriers which limit access to treatment and care. The project will also estimate
  surface molecules wher they are activated to mediate merger of the viral and cellular membranes. This project grant will explore how the viral glycopropteins become activated and obtain essenti
 o examine the epidemiology and transmission of the new influenza A (H1N1) and its impact on the community, as well asses the effectiveness of the control measure implemented by the Victorian
 s on how hepatitis C is transmitted amongst injecting drug users. The project will investigate whether particular types of social relationships between injecting drug users increase the chances of h
his process will hopefully lead to novel antiviral strategies to combat not only HCV but a broad range of other viral infections.
gi. We have identified a specific protein, RasGRP4, which is restricted to mast cells and plays an important role in their development and function. Understanding this molecule more extensively w
  and health economics approaches. We will compare the impact of a peer-education intervention, preventive HCV candidate vaccines and enhanced HCV treatment initiatives in various risk group
ccine trials in IDUs by answering key scientific questions, generating data to inform trial design and evaluation, establishing a partnership between leading international researchers and the peak A
ases increasing rapidly. This study will investigate the viral dynamics during primary HCV infection and its contribution to chronic infection. This will better inform clinicians on the need to provide an
o grow and spread. GSAO first needs to be processed by a tumour cell enzyme before it reacts with its mitochondrial target, so it should be more effective against tumours that make this enzyme.
  se diseases. Our research focuses on finding effective cures by identifying and targeting common host factors that are exploited by these viruses in establishing disease. We will use mouse and h
hem to sense pathogens and the functions of different DC types once a pathogen has been detected. The ultimate aim is to be able to understand and harness the functions of different DC so that
  ent of obesity and fatty liver. We discovered that Hepatitis C makes the liver more sensitive to these hormones, helping the hepatitis C virus to replicate. This project will determine the mechanism
 on from multiple causes and to develop specific strategies to monitor and improve the outcome of treatment in overweight patients with liver disease.
e to these new agents is the possible development of drug resistance. Studies suggest that drug resistant strains may already exist in some individuals prior to treatment. This study plans to use se
V have exploited these to abrogate antiviral immunity. This project attempts to define host factors that promote chronic infection. This will be extremely valuable in understanding the vulnerabilities
  osis and hepatocellular carcinoma. We have recently demonstrated genetic variants of the IL28B gene predict viral clearance with and without treatment after HCV infection. Determining why w
stical methodologies which will facilitate determination of the locations of these strategic mutations and assess the relative impact of different human-host genetic characteristics. Application of the
nsmission is critical. Antiviral treatment uptake remains very low in Australia, yet the prison environment offers a unique opportunity to address this. This project aims to assess effectiveness of e
  will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients
anisms are unable to respond effectively. We have recently identified a highly promising therapeutic target that enhances immune effector function. We seek to understand the underlying mechan
 e with a small risk of progression to liver cirrhosis and liver cancer over time. This study aims to evaluate the safety and efficacy of a two different treatment regimens among individuals with rece
 duals will develop long term complications from HCV. Recent studies have identified a genetic variant that is significantly associated with spontaneous viral clearance of HCV and response to trea
 ir shape to evade antibody responses and how this effects the outcome of infection. We will further characterize a vaccine that elicits protective immunity to HCV to identify the optimal formulation
 for miRNA-inhibiting drugs as novel antiviral agents against hepatitis C virus infection. By characterising how miRNAs control the antiviral state, we will gain new insights into how miRNA-modulati
ouples. However, there is little research in this area. This study will produce sophisticated and nuanced data able to capture the complexities of equipment sharing in couples and use these insight
h host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life
C. New directions will include development of international clinical cohort and trials networks, particularly to characterise the natural history of early hepatitis C infection and evaluate hepatitis C the
 se patients are at significantly increased risk of rapidly progressing to liver failure. It is now recognized that fat derived factors play an important role in regulating inflammatory responses. This gra
 f acquiring infection, our knowledge of hepatitis C has been hampered. The overall goal of this proposed research is to assess markers to better diagnose and predict clearance of hepatitis C, ass
agnosis is vital to patient survival. Our research investigates new methods in the early diagnosis of HCC, including new protein markers of the cancer and non-invasive measurements of liver scar
nd mortality in Australia and affecting hundreds of millions of people worldwide. This R&D program aims to develop a cheaper drug formulation that is easier to deliver and more stable for transpo
 nt a source of infection. Although the major route for transmission is blood and blood products, the advent of HCV screening in the blood banks has reduced the risk of infection from this source. H
 itis, as a model, and advanced techniques in biochemistry and electron microscopy, we have previously identified these membranes as the site of synthesis of the viral RNA or genetic material, an
ys in which it is spreading among IDUs. Much is known about risk behaviours of individual IDUs and how they contribute to HCV transmission; much less is known about how these behaviours are
at hepatitis C is likely to affect men in different ways to women, both economically, personally and physically. This is further complicated by the fact that the majority of infected men have a history o
ast Activation Protein (FAP) that may play a key role and the process of liver fibrosis (scarring). The aims of the project are four fold: (1) To characterise where and on what cells FAP is produced i
ose to examine disease progression using the new technology of gene array which scans thousands of genes simultaneously to find those most activated. Our preliminary experiments indicated th

ay play in the development of acute disease and of chronic infections with hepatitis B and C viruses. The findings will contribute to development of improved methods for the prevention and control

a chronic infection, usually resulting in recurrent, progressively worsening liver damage. Cirrhosis develops in 10-20% of chronic cases while 1-5% of chronic carriers develop liver cancer. Develop
alians are estimated to be living with hepatitis C infection. Around 11,000 new HCV infections per year are estimated to occur across the Australia. HCV is spread through blood to blood exposure.
serious liver disease, including liver cancer. HCV is currently the leading single indicator for liver transplantation in the western world. These carriers can also transmit the virus to uninfected individ

 available vaccine and treatment options are limited. While the host defense mechanisms to HCV are relatively well studied the role that viral proteins and viral replication play in the development o
 tent viral infections and metabolic disorders. The mechanisms causing fibrosis in liver are similar to those causing fibrosis in other organs such as kidney and heart. In those organs, the renin-ang
el exists with the exception of non-human primates. An authentic cell culture system is not available. The understanding of the immune response against this virus is important for the development

 the community as the majority of inmates are incarcerated for drug-related crimes, and injecting drug use remains prevalent whilst in prison. In addition, as almost one in two inmates are already i

atment against people with hepatitis C, in health care settings is a major barrier to care, treatment and support. A key strategy for developing effective strategies to reduce both perceived and real


involves liver progenitor cells; and this is usually observed when there is chronic and severe liver damage, particularly when the proliferation of hepatocytes is impaired. This study seeks to unders


elating to concerns about the risks of vertical transmission, the effects of the diease on their children and the use of Ribavirin, a teratogen, in HCV treatment. This study aims to elucidate the reaso
 ralians become infected, probably for life, with hepatitis C virus. Unless more effective treatments are developed approximately 20% of these infections will progress to liver failure or liver cancer w
ow fever virus. All viruses attach to target cells using receptors to initiate the infection process. In the case of HCV, the envelope glycoproteins interact with as yet unknown receptors on the target



. These increases in the prevalence of use and related harms have also been detected internationally. Previous research on psychostimulant drugs, in Australia and overseas, has suggested that
are resistant to the best contemporary treatment regimens. The aim of this project is to develop systems which will result in the assembly of virus particles which can be used to examine the efficac
years. Almost all new HCV infections in Australia occur among injecting drug users (IDUs), and despite our world-leading prevention programs, the virus is spreading. Consensus is emerging that


 ants will, in large part, explain the observed heterogeneity in the clinical outcome and course of HCV infection. The basic theory underpinning this research is that the evolution of viruses such as


significantly potentiates the severity of liver damage that is caused by other agents such as drugs or infections. To improve the prognosis of patients with fatty livers, it is important to understand wh

eath and of years of potential life lost, while liver cancer has recently doubled and is predicted to treble by 2020. The common causes are hepatitis C, fatty liver disorders, alcohol and hepatitis B; w

 at causes progressive liver disease, cirrhosis and in some cases liver cancer. The reason why some people are able to clear virus has been attributed to the development of a strong cellular immu
onses to these VLP vaccines will be aligned with GLP processes to support future clinical trials in man, providing support for the development of urgently needed vaccines against a range of infecti
d range of research issues within the broad framework of HIV and hepatitis C disease and treatment. CCIBS has become a leading centre of research excellence internationally, establishing a repu
stood. Preliminary studies have identified a link between an important alcohol-metabolising enzyme, Cyp2e1, HCV replication, oxidative stress and a powerful mediator of liver injury called tumour
er. To date we do not fully understand the mechanims that attract these cells to the liver but a class of molecules called chemokines is the most likely candidate. Thus a greater understanding of th
e bloodstream into the liver where they are involved in both viral control (but not viral clearance) and liver injury. The level of tissue injury observed and the speed of disease progression may be lin


There is now considerable evidence to indicate that the effect of HCV on the liver is due to ongoing immune activity and the build up of fat (steatosis) in the liver. This results in the production of bi

nological cascade might be targeted. In this project, we will test the hypothesis that HCV antigen induce supressor T cells This will have the effect of inhibiting the immune response and result in th
 40 % of patients and is often associated with severe side-effects. The mechanisms that HCV uses to replicate in liver cells is poorly understood. In this project we aim to better understand how the



als have shown that they are a successful delivery system for foreign epitopes or protein domains. Hepatitis C virus (HCV) and Influenza viruses are major human pathogens. HCV has infected 20
e response generated by individuals infected with Hepatitis C we intend to identify interactions which can be used to differientiate between the different stages of infection. The expected outcomes
ne responses are mounted and can be readily synthesised in the laboratory. If we were to design vaccines that are made of epitopes such that the immune response is focussed to those exact re

dy looks at one possible mechanism to explain the development of liver scarring. We believe that the normal repair mechanisms of the liver lead to the production of liver cells to replace those that
gan allografts. Not only are liver transplants well accepted, they can induce secondary acceptance of kidney or heart grafts from the same donor that would otherwise be rejected. However, this ab
ratory based and clinical approach and to identify markers that will predict treatment outcome.


 Research will also be done to understand the strategies and prevention tactics used by people with HCV to avoid passing it on to others.

 skills in basic virology and immunology with those providing expertise in translating findings in the laboratory into human clinical trials.
 ystems for the assessment and serial monitoring of the antiviral response will be of substantial benefit.
 isease. This will help doctors better advise patients as to what they can do themselves to improve the health of their liver.

aim to examine the effects of exercise on obesity and diabetes tendency in patients with CHC.
 ification of existing treatments and development of new therapies that will lead to improved outcomes for these individuals.
rogenitor cells. We will investigate how factors grow and convert them into liver cells for treating liver disease patients.
trategies to promote growth and differentiation of liver progenitor cell both in vivo and in vitro for therapies to treat liver diseases.
  effect of a novel Hepatitis B antiviral, tenofovir, on multi-resistant chronic Hepetatis B infection.
chronic infections. The results of this study will guide future vaccine design for HCV.

 dose regimen. This project is designed to overcome this limitation by using multiple vaccine delivery vehicles which encode common HCV proteins.
 me patient from which they were collected initially and are expected to elicit high levels of HCV immunity with the potential for cure.
sociated with disease outcome and treatment response, to identify novel targets for drug and vaccine development
t of IDUs remains uninfected. This project is therefore focused on understanding the innate immune mechanisms behind this protection.
 use established cohorts to define levels of hepatitis C risk through sexual contact among homosexual men to inform public health strategies.
e research that will identify new approaches to diagnosing and managing these infections while at the same time developing improved clinical guidelines and research capacity within the sector.
 ntext. The goal of this project is to evaluate an innovative model for the provision of assessment and treatment of HCV in opiate pharmacotherapy clinics
 project will also estimate the public health benefits which would result if the uptake of treatment was to reach its full potential.
vated and obtain essential structural information on the viral glycoproteins. These studies will help us to design antiviral agents.
emented by the Victorian government. Our work will provide important insight to inform both Australia’s ongoing response to new influenza A (H1N1), as well as the response elsewhere in the wor
 crease the chances of hepatitis C transmission and results will be used to inform future hepatitis C strategies.

cule more extensively will give us a much better understanding of diseases that the mast cell is involved in such as asthma and other disorders.
 ves in various risk groups on the number of HCV cases, HCV-related liver failure, liver cancer and transplants prevented, and associated cost savings.
earchers and the peak Australian body for people who inject drugs, and providing the foundation for a global HCV prevention trial network.
 n the need to provide antiviral therapy.
 that make this enzyme. My research will enable us to select cancer patients that are more likely to benefit from GSAO treatment.
We will use mouse and human models to identify and manipulate these factors and make them impervious to viral resistance mechanisms.
 s of different DC so that we may directly target them upon demand to aid in the course of infection or potentially as tumour therapy.
etermine the mechanisms by which CB1 antagonists prevent hepatitis C virus replication and their potential as a novel therapy for this disease.

 his study plans to use sensitive methods to examine how common drug resistant strains are in untreated individuals with acute hepatitis C.
nding the vulnerabilities of our immune system and provide an insight into how we can treat chronic infections.
 tion. Determining why will impact on the development of new therapies, optimise use of current therapies, and identify patients who may respond to alternative therapies.
  istics. Application of the results should benefit the design of tailored vaccines and studies of drug resistance.
assess effectiveness of existing prevention strategies, guide new control measures, and to evaluate a novel nurse-led model for treatment.
y, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially improving the safety and efficacy of therapy.
d the underlying mechanism, and to explore the therapeutic potential of this approach for the treatment of a broad range of pathogens, including those responsible for chronic disease.
ong individuals with recent Hepatitis C infection; and define the risk factors and natural history of Hepatitis C superinfection during treatment.
 CV and response to treatment for HCV. We propose to further investigate the functional basis for the effect of this human genotype on drug response.
   the optimal formulation for clinical trials.
  to how miRNA-modulating drugs could present novel strategies to treat viral infections.
es and use these insights to suggest recommendations for hepatitis C prevention strategies.
  nvestigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may uncover novel therapeutic strategies to combat HCV.
  evaluate hepatitis C therapuetic strategies for injecting drug users.
 ory responses. This grant proposal aims to gain insight into how liver and fat derived inflammatory factors interact to promote increased liver damage in chronic hepatitis C and obesity.
 rance of hepatitis C, assess hepatitis C transmission and assess health services to enhance HCV assessment and treatment among IDUs.
asurements of liver scarring. We also study the genetics of HCC and investigate new genes that could be targets for future therapies.
d more stable for transport to remote areas.
ection from this source. However, many intravenous drug users (IVD) share needles and although it is not common, transmission to spouses of carriers is well recognised. In addition, approximate
 A or genetic material, and the viral proteins involved. These comprise the viral replication complex. The research will define the origin of these membranes, and how the components of the associ
 w these behaviours are modified by the influence of the IDUs peer group, especially their immediate and intimate social networks. Despite its importance in influencing attitudes and behaviours, a
ted men have a history of injecting drug use, which coupled with the stigma often attached to chronic diseases such as hepatitis C, negatively impacts on men's lives. Of specific concerns are issu
t cells FAP is produced in the liver and whether FAP levels correlate with the development of fibrosis in human chronic liver diseases caused by either Hepatitis B or Hepatitis C virus infections. (2
 experiments indicated that one particular set of genes related to cell death is upregulated in HCV cirrhosis more than in other kinds of cirrhosis. We propose to pursue the diagnostic-prognostic po

e prevention and control of viral hepatitis.

op liver cancer. Development of an effective vaccine is complicated due to the highly variable nature of the virus. Approved therapies include alpha-interferon and alpha interferon-ribavirin combin
lood to blood exposure. In the absence of effective medical treatment for Hepatitis C virus (HCV) education about modes of transmission presents as the most viable means of containing the spre
virus to uninfected individuals. Screening in the blood banks has reduced transmission after blood transfusion to virtually zero. However, although individuals who share contaminated needles repr

 lay in the development of liver disease are not well characterized. Previous experiments in the laboratory have shown that one of the hepatitis C virus proteins results in the formation of toxic oxyg
se organs, the renin-angiotensin system has been shown to contribute to the progression of fibrosis. This system has not been investigated in hepatic fibrosis. We have recently shown in patients
ant for the development of potential vaccines. A potential vaccine must be able to induce a broad immune response to overcome the HCV quasispecies. Because of the relevant health issues, we

 wo inmates are already infected at the time of incarceration, those who are uninfected appear to be at significant risk of becoming infected through other (non-injecting) routes such as tattooing, fig

 both perceived and real discrimination of people with hepatitis C in health care settings is to gain a better understanding of the range of issues experienced by the health care providers themselves


 is study seeks to understand the underlying mechanisms which recruit liver progenitor cells for regeneration. This knowledge can lead to strategies to augment the oval cell contribution to liver reg


ms to elucidate the reasons for this low level of contraception among women with Hepatitis C through interviews with them (and in some cases their partners) about the complex array of practices a
 r failure or liver cancer within 30 years. Diabetes afflicts 150 million people, and 90% have Type 2 diabetes. We request funding of our research on a family of enzymes highly prospective as targe
  receptors on the target cell surface resulting in the virus being internalized into endosomes. It is believed that the low pH environment of these endosomes triggers fusion of the viral and cellular m



eas, has suggested that using these drugs in particular ways might be associated with a greater chance of contracting HIV and other blood-borne viruses such as hepatitis C (eg through sharing n
ed to examine the efficacy of potential antiviral agents, either in the test tube or by infecting an animal model. In particular, we will examine the contribution of a small viral protein, p7, on virus asse
sensus is emerging that the best hope for control of HCV and related disease lies in a vaccine; our research will lay much of the groundwork for its development. The applicants' research to date s


 ution of viruses such as HCV and HIV are influenced by the HLA type of the individual (hots), in combination with the ability of the virus to mutate (rid itself of deleterious mutations) to avoid the hos


 portant to understand why hepatic steatosis increases the risk for more serious liver disease. To date, much of our understanding of mechanisms of liver injury in fatty liver disease comes from an

alcohol and hepatitis B; when 2 of these are present together, there is a higher risk of cirrhosis. This program aims to unravel thepathological processes which cause cirrhosis at the molecular and

of a strong cellular immune response and antibody is belived to play a monir role in achieving viral clearance. However, measurememnt of antibody responses in HCV infected pateints is routinely
against a range of infectious diseases.
nally, establishing a reputation for innovative approaches to host-viral interactions that are built on a long tradition of research into the population genetics of both human and viral genomes, comb
ver injury called tumour necrosis factor alpha. Furthermore we have shown that alcohol metabolism by Cyp2e1 results in an increase in HCV replication and negatively impacts on the anti-viral act
eater understanding of the chemokines expressed in the liver, their modulation and role in attracting immune cells to the liver in HCV-related liver disease will help us understand the basic mechan
 e progression may be linked to the type of T cells recruited, their function, and their position in the liver. The aims of this project are to determine the factors involved in the fine positioning of T cell


ts in the production of biochemical products that lead to tissue damage and to eventual destruction of the liver. Further evidence has recently emerged to suggest that the susceptibility to, and out

esponse and result in the outcome that we currently recognise as persistent HCV infection.
etter understand how the viral glycoproteins, E1 and E2, function in the initiation of infection. In particular, we will examine how these glycoproteins bind to liver cell receptors and then mediate viru



ns. HCV has infected 200 million people worldwide, and there is no effective vaccine available. Influenza continues to affect thousands of people each year causing epidemics with severe morbidi
The expected outcomes of this study include the identification of a marker of recent Hepatitis C infection. This will permit accurate epidemiological monitoring of Hepatitis C, better design of progra
ussed to those exact regions of infectious agents it could lead to an immune response that eliminates the agent. The problem is, however, that we usually do not know which part of the virus, bact

ells to replace those that have died, but in some circumstances also produce small bile ducts that drain bile from the hepatocytes. These small bile ducts may have a previously unsuspected role in
jected. However, this ability of the liver to induce unresponsiveness may allow some viruses to persist, particularly , Hepatitis B and C. Four in every five patients infected with hepatitis C develop a
acity within the sector.



se elsewhere in the world. Our work will also inform Australia’s response to other new strains of influenza viruses that are likely to occur in the future. The project aims to understand the epidemiol




 to combat HCV.
 In addition, approximately 20% of HCV carriers have no recognised risk factor and it is unclear how these individuals became infected. Transmission of the virus to hospital inpatients and outpatie
omponents of the associated replication complex are assembled. Assembly of the virus particles in cells is also being analysed using similar technology. Hepatitis C virus cannot be reliably grown a
 tudes and behaviours, and therefore HCV transmission, this has never been studied in Australia, nor, in relation to HCV, in the world. We hope that by studying social and risk networks of IDUs we
pecific concerns are issues around employment, access to appropriate health care and social support. Six hundred men from Melbourne and regional Victoria will be surveyed. We will ask them qu
 itis C virus infections. (2) To examine a mouse strain in which the FAP molecule is knocked out ie absent. This will tell us whether FAP itself is essential for the development of fibrosis. (3) To isola
 diagnostic-prognostic potential of one of these molecules. Primarily this project will ask what kinds of genes are activated by HCV infection and at various stages of disease progression through to



erferon-ribavirin combinations but these treatments induce efficacious responses in only 20-30% of patients and often have severe side-effects. It is assumed that after attachment of HCV to the c
ns of containing the spread of the virus. The promotion of blood awareness has been identified as a key strategy for such education as it may ensure greater care on the part of the general commu
ntaminated needles represent a major high risk population, around 30% of carriers have no acknowledged transmission risk factors, and transmission to patients in hospitals has been recognised.

e formation of toxic oxygen molecules known as a reactive oxygen species. This toxic oxygen molecules can have an effect on liver cells that may enhance the progression of the liver disease proc
 ently shown in patients with chronic hepatitis C (HCV), that those patients who are genetically pre-disposed to produce higher levels of angiotensin have more liver fibrosis. This application will inv
levant health issues, we will generate virus-like particles (VLPs) derived from an envelope protein of hepatitis B virus (HBsAg-S) in which a variety of HCV-specific protein sequences are inserted.

 tes such as tattooing, fights and other coincidental blood exposures. This application seeks support for the HITS study (Hepatitis C Incidence and Transmission in Prisons study) - a prospective co

are providers themselves and factors in the broader health service context that impact on optimal care. The aim of this study is to identify these factors and the findings will influence policy and pra


 l contribution to liver regeneration in cases of chronic liver damage, to enhance survival of the patient. It can be applied to strategies to grow and maintain liver stem cells in culture for the purpose


 plex array of practices and understandings, within the contexts of their lives, that influence their contraceptive and reproductive behaviours. The public health outcomes of this research include the
ghly prospective as targets for novel therapies for these diseases. We are internationally recognised experts on this enzyme family and on liver disease. The prototype member of this enzyme fami
of the viral and cellular membranes. After fusion the genome of the virus is released into target cells and begins the replication process. The actual events intitiating these processes are not under



C (eg through sharing needles and syringes or other equipment associated with injecting drugs); sexually transmitted infections and other sexual health problems (eg through engaging in unsafe s
 rotein, p7, on virus assembly and secretion from the infected cell. Recent data suggests that p7 can function to help release virus from the infected cell and a number of inhibitors of p7 function ha
cants' research to date shows that IDUs are being infected with HCV more frequently than previously assumed, that many carry multiple strains, and that dominant strains vary rapidly in individuals


utations) to avoid the host's immune challenge (analogous to drug resistance) even at the lesser cost of impairing viral fitness or replication. We have shown that this is dependent on the immune


 disease comes from animal models, and these findings have not been systematically evaluated in the human disease. Apart from optimizing body weight, there is no established treatment of fatty

sis at the molecular and cellular levels, in order to understand why some people are at higher risk. These processes could result from genetic predisposition, other constitutional factors (age, gend

cted pateints is routinely performed using conventional diagnostic tests that do not measure antibody that can help neutralize and clear virus. We have developed an assay that accurately measur

nd viral genomes, combined with a willingness to negotiate complex computation and statistical challenges in order to faithfully reflect dynamic biological processes at a population level. An early r
 acts on the anti-viral action of interferon. The studies contained within this proposal aim to build on these exciting new insights by attempting to identify new mediators and mechanisms of liver dis
 stand the basic mechanisms of liver disease with the possibility of development of novel therapeutic strategies. In pilot studies we have shown that the chemokine interferon-inducible T cell alpha
 fine positioning of T cells in the liver and establish a relationship between T cell recruitment, function, and progression of HCV disease in the liver.


susceptibility to, and outcome of HCV infection may be influenced by genetic variation in the infected population. The chief investigators on this project have established the best characterised clin


 s and then mediate virus-cell membrane fusion. These processes lead to the penetration of the HCV genetic material into the cell where it is replicated. These studies are essential for the discove



mics with severe morbidity and considerable mortality. Current influenza vaccines are mostly inactivated formulations and they exhibit poor immunogenicity in immunological naive persons such as
 , better design of programs to control the spread, trace outbreaks and manage treatment programs. The identification of a marker capable of predicting the clinical outcome of infection would be in
ch part of the virus, bacterium or cancer cell is recognised as an epitope. So the identification of epitopes is a limitation to the design of epitope-based vaccines. Anyone who has encountered a vi

ously unsuspected role in stimulating the scar formation. The study will see if the small bile ducts are produced in a range of liver diseases in humans, and will use rodent models to find the factors
with hepatitis C develop a chronic disease due to the inability of the immune system to clear the virus. Although it is known that white blood cells enter the liver and become unresponsive, little is kn
nderstand the epidemiology, transmission and impact of new influenza A (H1N1) on the Victorian community. It will also assess the effectiveness of the control measures implemented by the Victo
 l inpatients and outpatients is also well recognised and as a result, it is clear that a vaccine is urgently required. However, as HCV cannot be cultured i
annot be reliably grown at present for research purposes in cultured cells, and we will attempt to develop a helper system to overcome the problem. An understandi
risk networks of IDUs we shall discover new ways in which control of the HCV epidemic can be achieved in Australia. We intend to do this among two groups of young IDUs,
yed. We will ask them questions about the social and personal impact of HCV on relationships with partners, the availability and accessibillity of approp
nt of fibrosis. (3) To isolate the cells within the liver that make FAP and to examine how particular functions of these cells are modified by FA
e progression through to fibrosis and cirrhosis and following liver transplantation to better understand these processes. We believe that this research is likel



achment of HCV to the cell surface, the virus is internalised by the cell and undergoes fusion with a cellular compartment referred to as an endosome. The low p
art of the general community in the prevention of blood exposures. However, the development of a heightened awareness of blood as a source of infection is fraught wi
 ls has been recognised. As a result, it is clear that members of the general population may still become infected. It has been estimated that there

 of the liver disease process in hepatitis C virus infected individuals. The role that these molecules play in liver cells is unknown but experiment
. This application will investigate the role of the renin-angiotensin system in hepatic fibrosis and whether using currently available drugs to
sequences are inserted. HBsAg-S wildtype particles can induce a strong immune response and are currently used as a vaccine against hepatitis B virus. These VLPs wil

 study) - a prospective cohort study of inmates of NSW prisons. Following a successful pilot in which the substantial bureaucratic and logistical

 influence policy and practice with the ultimate goal of removing barriers to equitable and appropriate health care for people with hepatitis C.


n culture for the purpose of cell and gene therapy to correct liver dysfunction. It is also necessary to identify factors which affect oval c


 this research include the development of contraceptive information that is relevant to the specific needs of women with Hepatitis C and the identification o
mber of this enzyme family, dipeptidyl peptidase (DP) IV, is being targeted by novel drugs that are in phase III clinical trials for Type 2 diabetes. Famil
processes are not understood for HCV but are believed to be mediated using two envelope glycoproteins. In this project we seek to gain



 gh engaging in unsafe sex); and of being involved in violent incidents. Despite this previous research, however, little is known about the specific social and cultural contex
hibitors of p7 function have been described. We will then use the systems which we develop to determine if these inhibitors can inhibit v
vary rapidly in individuals over time. These results reinforce the view that our prevention methods will not reduce infection rates and that current anti-viral treat


pendent on the immune environment that the virus encounters in relation to which HLA alleles are present in the host, therefore the escape is


blished treatment of fatty liver disease. Delineation of the mechanisms involved in liver injury will allow the development of specific pro

 tional factors (age, gender) or from lifestyle factors (overnutrition, inactivity, alcohol). The 3 chief investigators from Westmeads

y that accurately measures the level of NAb in patient sera. We have found that chronically infected patients have broadly reactive neutralizing antibodies but tha

 pulation level. An early recognition that large and integrated repositories of genetic and clinical data are fundamental to the research success in the genomic e
 mechanisms of liver disease as a consequence of Cyp2e1 expression, alcohol and HCV replication. We will also examine the molecular mechanisms by which alcohol poten
on-inducible T cell alpha chemoattractant (I-TAC) is significantly increased in the liver of persons infected with HCV. I-TAC is a member of the



e best characterised clinical cohort of HCV infected persons worldwide. Further, they have developed considerable expertise in the field of ge


 essential for the discovery of new targets for antiviral agents and vaccines.



al naive persons such as children and in the elderly. The influenza vaccines are not optimal for stimulation of cell-mediated immunity. We propose to use particulate anti
e of infection would be invaluable to clinicians, because following acute infection with Hepatitis C, 20 to 30% of individuals will resolve their inf
ho has encountered a virus, bacterium or tumour cell and who has raised an immune response will have developed antibodies and immune cells able to recognise the rig

models to find the factors responsible for stimulating the scarring. When the process is understood more clearly, it could lead to the development of
 unresponsive, little is known about the mechanisms that prevent an effective response. The CIA s work has been at the forefront of liver immunology and tr
mplemented by the Victorian government.

								
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