Permanent deafness drugs is found ? Scientists succeeded in developing a cure for permanent deafness problems. The drug is said to stimulate the inner ear. The drug, codenamed LY411575, can trigger the regeneration of sensory hair cells. Restoring sensory hair cells damaged by several factors, such as loud noises, infections, and toxic drugs, is not an easy job. In the present study, the scientists succeeded in developing a cure for the damage caused by loud noise in mice. Although the research is still quite preliminary, they believe that it could lead to effective treatment in humans. Small sensory cochlear hair is very important to hear. Sound vibrations is transferred from the eardrum which then moves the hair cells and causes nerve messages fired to the brain. Without the hair cells, the auditory pathway is blocked and there are no signal received by the auditory brain central. While birds and fish are able to regenerate hair cells in the ear, mammals can not. Therefore, the new approach involves reprogramming cells of the inner ear by blocking a protein called Notch. Laboratory studies have previously shown that Notch signaling helps prevent stem cells in the cochlea transform themselves into sensory hair cells. Well, the drugs LY411575 could suppress Notch. Hearing loss is a problem that affects 250 million worldwide “We found that hair cells can be regenerated from the surrounding cells in the cochlea,” said lead researcher, Dr Albert Edge, from Harvard Medical School in the United States, as reported by the Daily Mail . Hearing loss itself is an issue that has affected 250 million worldwide.
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