CURRICULUM VITAE JAMES J. STARK, M.D., F.A.C.P. BORN October 3, 1945 ADDRESS 116 Settlers Landing Road Suffolk VA 23435-1740 TELEPHONE (757) 484-0098; (757) 676-6354 (cell) E-MAIL jjstark@StarkOncology.com WEBSITE http://www.StarkOncology.com BLOG: http://starkoncologyconsulting.wordpress.com/ EDUCATION AND EXPERIENCE 1967 B.A. Yale University, cum laude 1971 M.D. Harvard Medical School, cum laude 1971-1973 Internship and Residency in Internal Medicine at Barnes Hospital and Washington University, St. Louis, Missouri 1973-1975 Active Duty, United States Public Health Service, National Health Service Corps, Philadelphia, PA 1975-1977 Fellowship in Medical Oncology at Dana-Farber Cancer Institute, Harvard Medical School and Brigham and Women's Hospital 1977-1988 Staff Physician, NDC Medical Center, Norfolk, VA (private practice) 1978-1982 Assistant Professor of Medicine, Eastern Virginia Medical School, Norfolk, VA (community faculty) 1983-1988 Associate Professor of Medicine, Eastern Virginia Medical School, Norfolk, VA (community faculty) 1988-1992 Full-time faculty as Chief, Hematology and Medical Oncology, Eastern Virginia Medical School and Associate Professor of Medicine 1992-1993 Chief of Medical Oncology, Midwestern Regional Medical Center, Cancer Treatment Centers of America, Zion, IL Apr-12 James J. Stark, M.D., F.A.C.P. p.2 1993-2002 Medical Director, Cancer Treatment Centers of America; President, Professional Corporation of Virginia, CTCA 1995-1998 Medical Director, Integrated Oncology Networks, CTCA 1997-2002 Associate Professor of Medicine, Eastern Virginia Medical School 2002-2011 Medical Director, Cancer Program, Maryview Medical Center, Portsmouth, VA 2002-2008 Private solo practice of Hematology and Medical Oncology 2002-present Professor of Clinical Internal Medicine, Eastern Virginia Medical School 2005-present Medical Director of Palliative Care, Maryview Medical Center 2006-2008 Medical Director of Hospice Program, Bon Secours Hampton Roads 2008-2011 Staff Physician, Oncology Division, Riverside Medical Group 2011-present President, StarkOncologyConsulting 2011-present Consultant to leadership group, Bon Secours Hampton Roads Current Licensure: Virginia CERTIFICATIONS 1972 National Board of Medical Examiners 1975 American Board of Internal Medicine 1977 Subspecialty of Medical Oncology MEMBERSHIPS American College of Physicians* (Elected, 1979; Fellow, 1999) American Society of Clinical Oncology* (Elected, 1979) Cancer Biotherapy Research Group (1988-2000) Southwest Oncology Group (1989-1992) National Surgical Adjuvant Breast and Bowel Project (1989-1992) Society for Biological Therapy (1988-2008) American College of Physician Executives (1993-1999) Portsmouth Academy of Medicine* Medical Society of Virginia* James J. Stark, M.D., F.A.C.P. p.3 American Medical Association (1993-1999) * currently held PRIOR HOSPITAL AFFILIATIONS Bon Sccours Maryview Medical Center, Portsmouth Bon Secours DePaul Medical Center, Norfolk, VA Riverside Regional Medical Center, Newport News Sentara Hospitals, Norfolk and Suffolk Chesapeake Regional Medical Center, Chesapeake PROFESSIONAL AND COMMUNITY ACTIVITIES AND AWARDS 1978-1992 Tidewater Cancer Network 1978-1983 Board of Directors, Tidewater Chapter of American Cancer Society 1981-1983 Board of Directors, American Society of Internal Medicine, Virginia Chapter 1981-1983 Physician Advisory Board, Blue Shield of Virginia 1981-1984 Board of Directors, NDC Medical Center 1982-1985 Board of Directors, Virginia Symphony 1984-1988 Director, Cancer Detection Project of NDC Medical Center 1987-1990 Medical Director, Oncology Special Care Unit, Sentara Norfolk General Hospital 1988-1992 Director, Tidewater Cancer Network 1988-1992 Principal Investigator, Norfolk Site, National Biotherapy Study Group 1988-1992 Member, Cancer Executive Committee, Sentara Norfolk General Hospital 1990-1995 Board of Directors, National Biotherapy Study Group 1990-1996 Study Chairman, Melanoma, Adenocarcinoma, Kaposi's Sarcoma and Bladder Cancer and Chronic Leukemia Protocols, NBSG 1992-1994 Parent fund-raiser, Phillips Academy, Andover, MA James J. Stark, M.D., F.A.C.P. p.4 1993-present Member, Cancer Leadership Council, Maryview Medical Center 1993-present Member, Cancer Committee, Maryview Medical Center 1994-2000 Principal Investigator, Cancer Biotherapy Research Group 1994-present Board of Advisors, Lee’s Friends 1994-2002 Chairman of Research Advisory Committee, CTCA 1995-1996 Parent Advisory Board to President of Purdue University, West Lafayette, IN 1996-2000 President’s Council, Purdue University, Cornerstone Member 1996-1999 Member ex-officio Board of Scientific Counselors, Cancer Treatment Research Foundation 1997-1998 Member, Cancer Committee, Eastern Virginia Medical School 1999-2002 Voting Member, Board of Scientific Counselors, Cancer Treatment Research Foundation 2000-present Medical Advisor, British Broadcasting Corporation (BBC) 2001-2003 Advisory Board to CEO of Maryview Medical Center on physician succession (retirement and replacement) 2002-2004 Physician representative to Committee on Complementary and Alternative Medicine, Maryview Medical Center 2002-2008 Monthly lecture series to the Maryview Nursing Services on oncology topics 2003 Ministering Spirit Award of Bon Secours Health System, presented on December 5. 2005-2009 Board of Directors, Leukemia and Lymphoma Society, Virginia Chapter OTHER PROFESSIONAL ACTIVITIES 1996-present Co-founder, Stark Software 2000-2002 Founder: Cancer Options, Website and Internet Company http://www.cancer-options.net James J. Stark, M.D., F.A.C.P. p.5 2000-2006 Consultant to: IT Medica, a software development company specializing in measuring cancer outcomes 2004-present Editorial Boards, Cancer Investigation; Nutrition and Cancer: An International Journal; Medical Science Monitor; Case Reports and Clinical Practice Review; Ophthalmic Plastic and Reconstructive Surgery; Indian Journal of Ophthalmology 2011-present Consultant to Virginia Board of Medicine COURSES TAUGHT AND SYMPOSIUM PRESENTATIONS (Professional and Community) Participant in tumor boards and cancer conferences, Sentara Norfolk General Hospital, De Paul Hospital and Maryview Medical Center, 1977-present. 1978: Medical Grand Rounds in advances in medical oncology, EVMS. Presented paper on Testicular Cancer at annual meeting of Virginia Chapter of American College of Physicians. 1982: symposium on lung cancer. symposium on advances in hematology and oncology. 1984: symposium on skin cancer jointly sponsored by EVMS and Chesapeake General Hospital. 1988: Biotherapy symposium sponsored by Sentara Norfolk General Hospital. 1988-1990: Board Review Course sponsored by Department of Internal Medicine, EVMS: Review of Medical Oncology 1989: CME course on topics in Internal Medicine (discussed breast cancer). 1990: symposium on immediate breast reconstruction sponsored by EVGSM and Department of Plastic Surgery. CME course on topics in Internal Medicine (discussed cancer detection). Symposium on breast cancer sponsored by Sentara Norfolk General Hospital. Medical Grand Rounds, EVMS on advances in GI malignancy. James J. Stark, M.D., F.A.C.P. p.6 1991: Symposium on breast reconstruction sponsored jointly by EVGSM and University of Florida School of Medicine. Symposium on Topics in Family Medicine sponsored by EVGSM, on cancer detection and treatment. Symposium on breast cancer sponsored by Tidewater Regional Cancer Network. 1992: Chaired session and presented paper on melanoma research at annual scientific meeting of Virginia Chapter of American Cancer Society Director, Biotherapy Symposium, sponsored by National Biotherapy Study Group, Sentara Cancer Institute and Division of Hematology/Oncology, EBMS 1993: Guest speaker (topic: advances in Biotherapy) in Oncology nursing seminar on recent developments in oncology, sponsored by Midwestern Regional Medical Center; held in Gurnee, IL. Speaker at Medical Grand Rounds, Midwestern Regional Medical Center; subject: Cancer Detection -- 1993. Speaker at Medical Grand Rounds, Chicago Medical School, North Chicago, IL; subject: Adjuvant Chemotherapy: 1993 1993-present: Moderator of tumor conferences at Maryview Medical Center, Portsmouth, VA 1994: Guest speaker, Oncology Nursing Society of Southeastern Virginia; subject: nutritional support of the cancer patient. 1996: Speaker on Chemotherapy of Neuroendocrine Tumors at NET symposium sponsored by EVMS Diabetes Institutes, Norfolk, VA (May 7). Speaker on Malignant Melanoma at symposium sponsored by Finch University of the Health Sciences, North Chicago, IL (June 26). 1997: Speaker at Disease Management Congress on Clinical Pathways in Oncology Management, Phoenix, AZ, (March 6). Speaker at Nursing Symposium on Cancer and the Kidney, Maryview Medical Center, Portsmouth, VA (May 15). 1999: Speaker at Symposium entitled HEALING: Prescriptions for Body, Mind and Spirit, sponsored by The Institute of Religion and Health. Talk on: Holistic Healing and Alternative Medicine: Fact vs. Fiction, Charleston, SC (March 6). 2000: EVMS Radio Rounds, Jan 10 and 11; topics: Cancer Detection and Cancer Prevention James J. Stark, M.D., F.A.C.P. p.7 Pros and Cons of Alternative Medicine, Presented at Lee’s Friends Biannual Retreat, Virginia Beach, VA (Feb. 19). Current Research Initiatives at Cancer Treatment Centers of America, presented to full- time faculty of the Department of Internal Medicine, EVMS, March 22. Evidence-based Alternative and Complementary Medicine, presented to Integrative Medicine and Internal Medicine Clubs, EVMS, April 6. Post-transplant Lymphoproliferative Disease, presented to tumor conference at Maryview Medical Center, June 23. Through a Glass Darkly: A Revisionist Look at Endocrine Tumors, Maryview Medical Center, August 18. New Approaches to the Treatment of Acute Myeloblastic Leukemia, Maryview Medical Center, September 29. 2001: Medical Grand Rounds, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA: The Role of Complementary and Alternative Medicine in the Prevention and Treatment of Cancer, January 31. Grand Rounds, Chesapeake General Hospital, Chesapeake, VA: The Role of Comple- mentary and Alternative Medicine in the Prevention and Treatment of Cancer, February 9. Guest speaker at annual meeting of Southeastern Virginia Chapter of Oncology Nursing Society: Complementary Medicine in the Prevention and Treatment of Cancer, February 21. Guest Speaker for continuing education forum given for the public and employees of Chesapeake General Hospital. Topic: Cancer and Nutrition: Holistic Healing for the New Millenium, February 28. Nelson, JK and JJ Stark, The Breasts of Night: Michelangelo as Oncologist? Presented at Italian Renaissance section of annual meeting of College Art Association, Chicago, IL March 2. Hodgkin’s Disease and Sarcoidosis. Presented at Maryview Medical Center, April 20. Chronic Myelogenous Leukemia: The impact of molecular biology on therapeutic options. Presented at Maryview Medical Center, August 3. The role of splenectomy in the management of Chronic Myelogenous Leukemia. Presented at Maryview Medical Center, October 5. James J. Stark, M.D., F.A.C.P. p.8 2002: Small-Cell Lung Cancer: Long-term Survivors? Presented at Maryview Medical Center, February 1. Guest Speaker at “Colon Cancer Survivors Day” sponsored by Maryview Medical Center March 21. Topic: Colon Cancer Prevention The Impact of Molecular Biology on Contemporary Cancer Therapy. Medical Grand Rounds, EVMS, April 17. The Impact of Molecular Biology on Contemporary Cancer Therapy: an Update. Presented at Maryview Medical Center, May 31. Cancer of the Anus. Presented with Paul J. Kovalcik, MD, FACS at Maryview Medical Center, August 9. The Problem of the Unknown Primary Tumor. Presented at Maryview Medical Center, October 18. Neuroendocrine Large Cell Carcinoma of the lung. Presented with Joan Tryzelaar, MD, FACS, at Maryview Medical Center, November 8. 2003: Good Syndrome: Case report and review of the literature. Presented at Maryview Medical Center, January 31. Ocular lymphoma in a patient with Graves’ Disease: Case report and review of the literature. Presented at Maryview Medical Center on February 21. Frontiers in the Treatment of Colorectal Cancer: Role of New Ideas and New Agents. Presented at Colon Cancer Survivors Night, Maryview Medical Center, March 13. Immunosuppression (non-AIDS) and Cancer. Presented at Maryview Medical Center on June 6. Advances in the treatment of Multiple Myeloma. Presented at Maryview Medical Center on September 12. Sickle-cell Disease in the Fifth Decade. Medical Grand Rounds, EVMS, October 8. Recent Advances in Breast Cancer Treatment. Presented at Breast Cancer Survivors’ Night at Harborview Medical Center, Suffolk, VA on October 23. Rectal lymphoma. Presented with Paul J. Kovalcik, MD, FACS, at Maryview Medical Center on December 12. James J. Stark, M.D., F.A.C.P. p.9 2004: Hodgkin’s Disease: presented to Internal Medicine residents, Sentara Norfolk General Hospital, January 29. Sarcoma and Metabolic Bone Disease: A Failed Safari. Presented with Frank Kohler, D.O. at Maryview Medical Center on February 6. Two Unusual Intestinal Masses Presented with Paul J. Kovalcik, MD, FACS, at Maryview Medical Center on February 27. Recent advances in colon cancer. Presented at Colon Cancer Survivors Night, Harborview Medical Center, March 11. Failure to Screen for Cancer: Medical Malpractice in the New Millenium. Presented with A. William Charters, Esq. at Maryview Medical Center, April 2. Hodgkin’s Disease: Current Status. Presented at Maryview Medical Center, April 23 Phakomatoses and Cancer. Presented at Maryview Medical Center, June 11. The New Malpractice Crisis: Failure to Screen for Cancer. Presented at Medical Grand Rounds, EVMS, August 11. Adjuvant chemotherapy for Stages I and II non-small-cell lung cancer. Presented at Maryview Medical Center, October 22. Evidence-based Cancer Prevention in 2004. Presented at Maryview Medical Center, December 10. 2005: The Variable Natural History of Renal Cell Carcinoma. Presented at Maryview Medical Center, February 25. Breast Cancer Prevention and Diagnosis. Presented at Women’s Health Symposium at Harborview Medical Center, Suffolk, VA, March 15. The New Malpractice Crisis: Failure to Screen for Cancer. Presented at monthly meeting of Oncology Nursing Society, Portsmouth, VA March 16. Sickle Cell Anemia in the Fifth Decade. Presented at Maryview Medical Center, April 22. Cancer of the Renal Collecting System, Presented with Dr. William Julian at Maryview Medical Center on June 3. The Antiphospholipid Syndrome: Thrombophilia. Presented at Maryview Medical Center, July 8. James J. Stark, M.D., F.A.C.P. p.10 Oncologic Emergencies. Presented as part of the core curriculum to PGY-1 trainees of the EVMS Department of Internal Medicine, Norfolk, VA, July 20. Systemic Amyloidosis: New Treatment Strategies, Presented at Maryview Medical Center, August 12. Breast Cancer, 2005 Presented to First Annual Symposium on Breast Cancer Awareness at Maryview Medical Center, October 7 and Cancer Support Group, October 11. Oncologic Emergencies Presented at Maryview Medical Center, October 14 Colon Cancer Presenting with Metastatic Disease: Management Issues, Presented at Maryview Medical Center on November 18. 2006: Futile Care in a Climate of Fear Presented with Madeline Stark, JD, Stephen Heretick, JD and Bonnie Brown, risk manager at Maryview Medical Center, January 27 Cytogenetics for the Rest of Us: A Primer Presented with Diane Maia, MD, at Maryview Cancer Conference, March 3. Update on Colon Cancer Therapy, for Colon Cancer Awareness Month. Presented at Harbour View Medical Center, Suffolk, VA March 15. Complications of Cancer Therapy, Part I. Presented at Maryview Medical Center on June 9. Tyrosine Kinase: From Molecule to Bedside. Presented at Eastern Virginia Medical School Department of Internal Medicine Grand Rounds, August 9. Complications of Cancer Therapy Part II: Metabolic Bone Disease and Its Treatment, Presented at Maryview Medical Center, October 27. 2007: Breast Cancer in Young Women: Sexuality and Survival. Presented with Linda Long, MD, FACOG, at Maryview Medical Center, January 19. Adult Osteogenic Sarcoma. Presented at Maryview Medical Center, March 9. Thyroid Lymphoma: A modern approach to the diagnosis of an uncommon but clinically important lesion. Presented with Stephen I. Fisher, MD at Maryview Medical Center, April 20. Recent Advances in Cancer Diagnosis and Treatment. Presented at North Suffolk Rotary Club, May 18. Complications of Cancer Therapy Presented at Medical Grand Rounds at Eastern Virginia Medical School, May 23. James J. Stark, M.D., F.A.C.P. p.11 Lung Cancer in Women: A Different Disease? Presented at Maryview Medical Center, July 20. The Pre-Operative Evaluation of the Patient with Abnormal Clotting Studies, Presented at Maryview Medical Center, August 24. Invited Speaker at International Endocrine Tumor Symposium, Sponsored by EVMS, September 28, Sheraton Waterside Hotel, Norfolk Breast Cancer: Who Gets It and Who Survives? Presented at Maryview Medical Center on October 12. Stage III Lung Cancer. Presented at Lung Cancer Symposium on November 15 sponsored by the Lung Chest Program at Maryview Medical Center at the Towne Point Club, Norfolk. Bisphosphonates in Health and Disease, Presented at Maryview Medical Center, November 16. 2008: Hepatocellular Carcinoma, Presented at Maryview Medical Center, January 25. Treatment of Locally Advanced Rectal Cancer: Current Concepts, March 27, presented at: “Colon Cancer: Detection, Prevention and Risk Reduction” at Hilton Garden Inn, Suffolk, VA Ductal Carcinoma-in-Situ: New Concepts and Controversies, April 18, presented at Maryview Medical Center. Osteoporosis: An Overview of the Disease and Its Consequences, April 24, presented at Spirit of Women presentation, Harbour View Medical Center. Autoimmune Hemolytic Anemia, July 18, presented at Maryview Medical Center New Trends in Oncology, August 1, presented at Annual Meeting of Bangladeshi Medical Association of North America at Norfolk Convention Center, Norfolk, VA Non-Seminomatous Testicular Cancer: The Poor Risk Patient, September 19, presented at Maryview Medical Center Mantle-Cell Leukemia: Lessons in Life and Death, presented at Maryview Medical Center, November 6. Melanoma Presenting as Unknown Primary with Lymph-Node Metastasis, presented with Dr. Jeff Riblet at Maryview Medical Center, November 21. James J. Stark, M.D., F.A.C.P. p.12 Topics in Thyroid Cancer: Insular Carcinoma and Tyrosine Kinase Inhibitors, presented with Dr. James LaRocque at Maryview Medical Center, December 19. 2009: Renal Cell Carcinoma: The First Sign of Von-Hippel Lindau Disease, presented with Dr. William Julian at Maryview Medical Center, January 9. Myeloproliferative Disorders: Diagnostic Enigmas, Therapeutic Dilemmas, presented at Maryview Medical Center, February 13. Bladder Cancer: Long term survivors with metastatic disease. Presented with Dr. William Julian, February 20. Osteoporosis in Youth, Aging and Illness. Presented at Riverside Regional Medical Center Grand Rounds, April 29. Gastric Lymphoma: Incidental Finding or Life Threatening Illness, presented at Maryview Medical Center on August 21. Unusual Complication of Iron Overload: Hemochromatosis? Presented at Maryview Medical Center on November 20. Palliative Care at Maryview Medical Center, Presented with Jennifer Ward, ANP- BC, ACHPN, AOCNP, December 18 2010 Liver Disease in Sickle Cell Anemia, presented with Dr. Elizabeth Gunderson at Maryview Medical Center, January 15. Update on the Adjuvant Therapy of Malignant Melanoma, presented at Maryview Medical Center, June 25. The Impact of Molecular Diagnostics on Contemporary Cancer Management. Presented at Medical Grand Rounds, Eastern Virginia Medical School, August 11. Ocular Melanoma Revisited Presented at Maryview Medical Center, October 11 2011 Chemotherapy for Bladder Cancer Revisited, presented at Maryview, January 26 Hormone-resistant Prostate Cancer, presented at Maryview Medical Center, March 11. Meetastatic Melanoma from Unknown Primary, presented at Maryview March 25 Unusual Complication of Melanoma therapy, presented at Maryview May 22 2012 Medical Errors: How and Why Good Doctors Make Bad Mistakes. Presented at Medical Grand Rounds, Eastern Virginia Medical School, April 12. James J. Stark, M.D., F.A.C.P. p.13 Internal Medicine Board Review Course given to PG III Internal Medicine Residents to prepare them for the Oncology Section of the Internal Medicine Board Examination, March and April, 2012. FUNDED RESEARCH Foundation Funding: Micronutrient Intervention Trial: A Pilot Study, funded by Cancer Treatment Research Foundation at $155,000 (principal investigator and author of grant proposal) (1999-2001). Pharmaceutical Company Research (selected trials, acting as site principal investigator): Pfizer: A Phase III trial of liposome encapsulated Doxorubicin versus Doxorubicin in the treatment of metastatic breast cancer (1996-1997). Alfacell, Inc.: Onconase® versus Doxorubicin: A Phase III trial in the treatment of mesothelioma (1995-1997). Eli Lilly: LY231514 (MTA): A Phase III trial for the treatment of mesothelioma (2000-2001). Vical, Inc.: VCL-1005-301: A Phase III trial for the treatment of metastatic melanoma (2000- 2002). Ligand Pharmaceuticals: A Phase III trial of best available chemotherapy with or without Targretin® in patients with Stage IIIB and IV lung cancer (2002-2003). Amgen: Quality of Life Study for patients receiving growth-factor support (2003-2004). Amgen: Quality of Life Study in patients receiving Pegylated Filgrastim (2004-ff). Syntapharma: Combination therapy for the treatment of advanced melanoma with Paclitaxel plus or minus STA-4783: a Phase III trial (2004-2006). Numerous funded trials through ACORN (Accelerated Community Oncology Research Network) 2008-2011. PUBLICATIONS -- ORIGINAL CONTRIBUTIONS Stark, JJ, CA Sanders and WJ Powell, Jr. Neurally Mediated and Direct Effects of Acetylstrophanthidin on Canine Skeletal Muscle Vascular Resistance, Circulation Research 30: 274-282, 1972. James J. Stark, M.D., F.A.C.P. p.14 Willerson, JT, WJ Powell, Jr., TE Guiney, JJ Stark, CA Sanders and A Leaf Improvement in Myocardial Function and Coronary Blood Flow in Ischemic Myocardium After Mannitol, Journal of Clinical Investigation 51: 2989-2998, 1972. Stark, JJ and SB Howell Clinical Investigations of the Nephrotoxicity of Cis-platinum (II) Dichlorodiammine, Clinical Pharmacology and Therapeutics 23: 461-466, 1978. Garnick, MB, GP Canellos, JP Richie and JJ Stark Sequential Combination Chemotherapy and Surgery for Disseminated Testicular Cancer, Cancer Treatment Reports 63:1681-1686, 1979. Stark, JJ, JW Lloyd and PF Schellhammer Estrogen Receptor Activity and Hormonal Responsiveness in a Patient with Hodgkin's Disease, Ann Int Med 95: 186-187, 1981. Pesando, JM, SE Come, JJ Stark, LM Parker, CT Griffiths, and GP Canellos Cis Diamminodichloro Platinum (II) Therapy for Advanced Ovarian Cancer. Cancer Treatment Reports 64: 1147-1148, 1981. Oldham, RK, J Stark, NM Barth, B Hoogstraten, CH Brown, T O'Connor, S Dupere and R. Birch Continuous Infusion of Interleukin-2 and Cyclophosphamide as Treatment of Advanced Cancers: A National Biotherapy Study Group Trial, Molecular Biotherapy 3: 74-78, 1991. Stark, JJ Epilogue to Eastern Virginia Cancer Statistics Review: 1985-1989. Edited by AJ Rosenthal. 1992, published by Tidewater Regional Cancer Network. Stark JJ Sequencing of Chemotherapy and Radiotherapy in Breast Cancer. Letter to the Editor (ré: Recht A et al N Engl J Med 334:1356-61, 1996). New England Journal of Medicine 335:1240, 1996. Stark JJ, R Dillman, R Schulof, M Wiemann, N Barth, P Honeycutt and G Soori Interferon- and Chemohormonal Therapy for Patients with Advanced Melanoma: Final Results of a Phase I-II Study of the Cancer Biotherapy Research Group and the Mid-Atlantic Oncology Program CANCER 82 (9): 1677-81, 1998. Miller, DR, GT Anderson, JJ Stark, JL Granick and D Richardson Phase I/II Trial of the Safety and Efficacy of Shark Cartilage in the Treatment of Advanced Cancer. Journal of Clinical Oncology 16 (11): 3649-55, 1998. Soori, GS, RS Schulof, JJ Stark, MC Wiemann, PJ Honeycutt, CK Church and CB DePriest Continuous Infusion Floxuridine and Alpha Interferon in Metastatic Renal Cancer: A National Biotherapy Study Group Phase II Study. Cancer Investigation, 17 (6): 379-384, 1999. Stark, JJ and JK Nelson The Breasts of “Night”: Michelangelo as Oncologist. New England Journal of Medicine, 343 (21): 1577-8, 2000. Soori G, RO Dillman, MC Wiemann, JJ Stark, DF Tai, CB DePriest, CK Church and R Schulof Phase II Trial of Subcutanious Interleukin-2, Subcutaneous Interferon-, 5-Fluourouracil and James J. Stark, M.D., F.A.C.P. p.15 Cis-retinoic Acid in the Treatment of Metastatic Renal Cell Carcinoma: Final Results of Cancer Biotherapy Research Group 94-10. Cancer Biotherapy and Radiopharmaceuticals 17 (2):165- 173, 2002. Stark JJ. Prevention of Hepatocellular Carcinoma. Annals of Internal Medicine 141 (1): 77, 2004. Stark, JJ, J Roman, RM Newsom, D Richardson and JC LaRocque Orbital MALT Lymphoma in a Patient with Graves’ Ophthalmopathy: a Unique Observation, Cancer Investigation 23:593-5, 2005. Dillman RO, MC Wiemann, F Tai, CB DePriest, G Soori, JJ Stark, K Mahdavi, C Church Phase II Trial of Subcutaneous Interferon Followed by Intravenous Hybrid Bolus/Continuous Infusion Interleukin-2 in the Treatment of Renal Cell Carcinoma: Final Results of Cancer Biotherapy Research Group 95-09. Cancer Biotherapy & Radiopharmaceuticals. 21(2):130-7, 2006. Stark, JJ Electronic Health Records: Who Pays? Annals of Internal Medicine 145 (11):864, 2006. Watring, NJ, Wagner TW and Stark JJ Spontaneous splenic rupture secondary to pegfilgrastim to prevent neutropenia in a patient with non-small-cell lung carcinoma. Am J Emerg Med 25 (2):247-8, 2007 Stark, JJ Alcaligenes xylosoxidans osteomyelitis without trauma in a patient with Good syndrome, European Journal of Internal Medicine, 18 (5):447, 2007. Stark, JJ Frontispiece text for Bland and Copeland, eds. The Breast: Comprehensive Management of Benign and Malignant Disorders 4th edition Elsevier Publishers, Philadelphia, PA, 2009, p. ii. PUBLICATIONS – REVIEWS Stark, JJ An Approach to the Patient with Testicular Cancer, in The Cure of Cancer, a syllabus prepared for a course sponsored by Harvard Medical School, 1977. Canellos, GP and JJ Stark Medical Emergencies in Oncology, in Cancer: A Manual for Practitioners Massachusetts Division of American Cancer Society, 300-306, 1979. Stark, JJ Cancer of the Pancreas -- Diagnosis and Treatment, Virginia Medical Monthly 108: 541-543, 1981. PUBLICATIONS – INVITED EDITORIALS James J. Stark, M.D., F.A.C.P. p.16 Stark, JJ, T Birdsall, G Anderson, D Nixon E Zang and G Haase Micronutrient Supplementation for Patients with Metastatic Cancer. Nutrition and Cancer 38 (2): 296-298, 2000. ABSTRACTS Stark, JJ SB Howell and J Carmody Prevention of Cis-platinum Nephrotoxicity. Clinical Research.25: 412A, 1977. Stark JJ, MB Garnick and GP Canellos The Value of Surgical Restaging in Advanced Testicular Cancer, Virginia Medical Monthly January, 1978, p. 61. Oldham, RK, J Stark, N Barth, B Hoogstraten, CH Brown, S Dupere, R. Birch Treatment of advanced cancers with cytoxan (CTX) and interleukin-2 (rIL-2): a phase II study. Proc Am Assoc Cancer Research 31:268, 1990. Stark, JJ RS Schulof and M Wiemann Alpha Interferon and Chemo-Hormonal Therapy in Advanced Melanoma: A Phase I-II National Biotherapy Study Group/Mid-Atlantic Oncology Program Study. Presented at sixth annual meeting of Society for Biological Therapy, November 16-19, 1991, p. 20 of abstract booklet. Stark, JJ, R Schulof, M Wiemann, N Barth and P Honeycutt Alpha Interferon and Chemo- Hormonal Therapy in Advanced Melanoma: Update of A Phase I-II NBSG/MAOP Study Journal of Immunotherapy 13 (1): 72-73, 1993. Stark JJ, R Schulof, M Wiemann, N Barth, P Honeycutt and G Soori Alpha Interferon and Chemo-Hormonal Therapy in Advanced Melanoma: A Phase I-II NBSG/MAOP Study Proc Am Soc Clin Onc 12 (3):392, 1993. Soori G, R Schulof, J. Stark, M. Wiemann, P. Honeycutt, J. Arnold and C. Church Phase II Trial of Continuous Infusion (CI) Floxuridine (FUDR) and interferon-Alpha-2b (a-IFN-2b) in Advanced Renal Cancer -- An NBSG Study Proc Am Soc Clin Onc 12 (3):236, 1993. Hankenson R, H Nevinny, A Hankenson, F Brunk, J Stark, D Miller, and RM Williams Malignant Epidural Spinal Cord Compression in Breast Cancer Proc Am Soc Clin Onc 12 (3):86, 1993. Soori G, R Schulof, J Stark, M Wiemann, R Langdon and M Block Continuous Infusion Floxuridine and Interferon-Alpha 2b in Advanced Renal Cancer -- An NBSG Phase II Study. Presented at eighth annual meeting of the Society for Biological Therapy, November 10-14, 1993 in Nashville, TN p. 56 abstract book. Stark J, J Frank, J Granick, D Miller, R Levin, P Sirijintakarn, D Wong, R Sanchez, A Mellijor and RM Williams Combined Intra-arterial and Intravenous Chemotherapy for Locally Advanced Carcinoma of the Pancreas. Proc Am Soc Clin Onc 13 (3):226, 1994. James J. Stark, M.D., F.A.C.P. p.17 Stark JJ, R Schulof, M Wiemann, N Barth, P Honeycutt and G Soori Alpha Interferon and Chemo-Hormonal Therapy in Advanced Melanoma: Final Results of a Phase I-II Study. Presented at the Sixteenth Annual Seminar of Cancer Researchers in Virginia, March 30, 1996, in Norfolk, VA Abstract #50 in program book. Miller DR, JL Granick, JJ Stark, GT Anderson Phase I/II Trial of the Safety and Efficacy of Shark Cartilage (Cartilade) in the Treatment of Advanced Cancers. Proc Am Soc Clin Onc 16:49a, 1997. Soori G, JJ Stark, MC Wiemann, PJ Honeycutt, BE Cogburn, DF Tai, C DePriest, LA Potts, C Church, R Schulof, and RO Dillman Outpatient Phase II Trial of Alpha Interferon, Subcutaneous Interleukin-2, 5-Fluorouracil, and Cis-Retinoic Acid in Patients with Metastatic Renal Cell Cancer. Proc Am Soc Clin Onc 16:344a, 1997. Soori G, JJ Stark, M Wiemann, P Honeycutt, D Tai, T Dobbs, R. Langdon, B Cogburn, M Block, P Townley, R Dillman, C Church, and C DePriest Outpatient Phase II Trial of Alpha Interferon, Subcutaneous Interleukin-2, 5-Fluorouracil and Cis-Retinoic Acid in Patients with Metastatic Renal Cell Cancer. Proc Am Soc Clin Onc 18: 352a, 1999. Dillman RO, MC Wiemann, F Tai, CB DePriest, G Soori, JJ Stark, K Mahdavi, and CK Church Phase II trial of subcutaneous interferon followed by hybrid bolus/continuous infusion Interleukin-2 in the treatment of renal cell carcinoma: final results of Cancer Biotherapy Research Group (CBRG) 95-09. Submitted to the 2005 meeting of the Society for Biological Therapy. Watring, NJ, JJ Stark, and TW Wagner Spontaneous splenic rupture after pegfilgrastim administration. Presented at Eastern Virginia Medical School 18th Annual Research Day.
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