American Society for Clinical Pathology 2004 Resident In-Service Examination Item Descriptors
Anatomical Pathology Cytopathology 1. Desmoid-type fibromatosis; no metastatic potential 2. Hodgkin's disease; fine-needle aspirate neck 3. Mesothelial cell; staining pattern 4. Papillary carcinoma; aspirate thyroid nodule 5. Chromagranin; fine-needle aspiration liver 6. Mesothelial cells; effusions 7. Fine-needle aspiration biopsy; nodular fasciitis 8. Carcinoma of breast; intracytoplasmic lumens 9. Radiation effect; Pap smear 10. Cervical smears; tissue sections 11. High grade squamous intraepithelial lesion; Pap smear 12. Atypical squamous cells of undetermined significance; reporting definition 13. Carcinoma; fine-needle aspiration of breast mass 14. Subareolar abscess of the breast; ruptured epidermal inclusion cyst 15. Meningioma; fine-needle aspiration of a scalp lesion 16. Adenocarcinoma in situ; Pap smear 17. Colloid carcinoma; fine-needle aspirate breast 18. Bilateral mass; fine-needle aspirate breast 19. Reserve cells; small cell undifferentiated carcinoma 20. Bronchioalveolar carcinoma; fine-needle aspiration lung 21. Follicle center lymphoma; fine-needle aspiration lymph nodes 22. Aspirate of solitary thyroid nodule; lesion excised 23. Busulfan; mimic cancer 24. Course of acyclovir; Pap smear 25. Cryptococcus neoformans; fluid aspirated thigh abscess 26. Warthin's tumor; bilateral parotid tumor 27. Gleason pattern3+4; prostatic adenocarcinoma 28. Contamination; urine cytology specimen 29. Sarcomatoid renal carcinoma; any histologic type 30. Chromophobe renal carcinoma; outcome 31. Renal carcinoma; t(X;1) (p11.2;q21) chromosome translocation 32. Endometrial cells; Bethesda 33. Intractable gastric ulcers duodenal wall mass; peripancreatic lymph node 34. Benign mixed tumor; fine-needle aspiration jaw 35. Warthin tumor; fine-needle aspiration parotid 36. Small cell carcinoma; sputum Forensic Pathology 37. Hypothermia; Anatomic findings 38. Stomach contents; cocaine toxicity 39. Incised wound; laceration 40. Designer drugs; modifying the structure 41. Gunshot wound; exit 42. Postmortem change; lesions 43. Atlantooccipital dislocation; vehicle accident death 44. Vitreous fluid; hyperglycemia 45. Drowning; other causes of death 46. Ateriosclerotic heart disease; sudden and unexpected death 47. Postmortem interval; > 16 hours 48. Temporal and frontal lobe contusions; fall on the back of the head 49. Gunshot wound; high velocity military rifle 50. Injury on the arm; bite mark impression 51. Sudden infant death syndrome; heart 52. Man without a spleen; Gram stain of meninges 53. Manual strangulation; fracture of the hyoid bone 54. Homicide; manner of death 55. Mechanism of death; septicemia
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Surgical Pathology 56. Paget’s disease; regional carcinoma 57. Thyroid cancer; age 58. Breast neoplasms; worst prognosis 59. Intramuscular myxoma; gelatinous tumor of the thigh 60. Gynecomastia; Ultrastructural features 61. Intratubular germ cell neoplasia; placental alkaline phosphatase 62. Anogenital verrucous carcinoma; description 63. Renomedullary interstitial cell tumor 64. Renal artery; Fibromuscular dysplasia 65. Adenocarcinoma of the urinary bladder; enteric carcinomas 66. Erythema nodosum; characterization 67. Contact allergy; Lichenoid interface dermatitis 68. Progressive multifocal leukoencephalopathy; characteristics 69. Fibroadenoma of the breast; greatest incidence 70. Mulitcystic renal dysplasia; renal mass, primitive ducts 71. Dermatofibrosarcoma protuberans; CD34 positive 72. Subacute sclerosing panencephalitis; slowly progressive neurodegenerative disease 73. Osteoblastoma; flat bones 74. Dermatitis herpetiformis; gluten-sensitive enteropathy 75. Colon biopsy; labeling of collagen 76. Pulmonary lesion; lumen of a large airway 77. Seminoma 78. Cervical tunnel clusters; dilated endocervical glands 79. Testicular tumor; 1-year-old 80. Solitary fibrous tumor of pleura; increased recurrence 81. Familial adenomatous polyposis syndrome; genetic abnormality 82. Ground glass hepatocytes; Hepatitis B 83. Malakoplakia; Escherichia coli 84. Primary sclerosing cholangitis; primary biliary cirrhosis 85. Metastatic papillary cancer; good prognosis 86. Hashimoto's thyroiditis; thyromegaly 87. Giant cell (temporal) arthritis; Associated findings 88. Pure hepatic canalicular cholestasis; sepsis 89. Adenomatoid tumor 90. Cerebral hematoma metastatic tumor; beta HCG 91. Kaposi's sarcoma; multiple organs 92. Biopsy from the great toe; polarized light 93. Cervical lymph node biopsy; Epstein Barr-virus testing 94. Enchondroma; low grade central chondrosarcoma 95. Gastrectomy specimen; ascites and bilateral ovarian masses 96. Osteoarthritis; femoral head 97. Yelloe fever; necrosis 98. Small intestinal tumor; interstitial cells of Cajal 99. Low grade sil; eventual regression 100. Gastrointestinal tract dysplasia; unequivocally neoplastic epithelium 101. Gallbladder; stones 102. Adenocarcinoma of the lung; predictor of survival 103. Invasive mammary carcinoma; appearance 104. Liposarcomas; prognostic indicator 105. Thymoma; myasthenia gravis 106. Polymorphous low-grade adenocarcinoma of minor salivary gland; oral cavity 107. Lobular carcinoma of the breast; Classic-type invasive 108. Pseudoangiomatous change; breast 109. Inflammatory breast cancer; dermal lymphatic invasion 110. Osteoid osteoma; osteoblastoma 111. Common primary malignant neoplasm; malignant fibrous histiocytoma 112. Nodular fasciitis; characteristics 113. Epithelioid sarcoma; positive for cytokeratins 114. Esophagitis; mid-esophagus biopsy 115. Crohn's disease; a gastric biopsy 116. Anti-gliadin antibodies; lymphocytic colitis
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117. 118. 119. 120. 121. 122. 123. 124. 125. 126. 127.
Peutz-Jehger's polyposis; small bowel Jejuno-ileal carcinoid tumors; fibroblastic reaction Ulcerative colitis; biopsies Colon biopsies; H&E and trichrome-stained Focal nodular hyperplasia; young women Genetic hemochromatosis; stainable iron Primary sclerosing cholangitis; cholangiocarcinoma Esophageal adenocarcinoma; gastroesophageal reflux Helicobacter pylori gastritis; atrophic gastritis Gastric adenocarcinoma; atrophic gastritis Gastric stromal tumors; c-kit gene
Clinical Pathology Clinical Chemistry 128 Major intracellular cation; K+ 129. Prostate specific antigen; monitoring 130. Serum osmolality; calculation 131. Transthyretin; nutritional status 132. Distal renal tubular acidosis; normal anion gap 133. Loop diuretics; mechanism 134. Methanol ingestion; serum osmole gap 135. LDL cholesterol levels; 160 mg/dL 136. LDL subclasses; Higher risk 137. PKU; screening tests 138. Pituitary gland; prolactin secreting tumor 139. Method comparison; precision 140. Fetal fibronectin; negative 141. Diabetes Mellitus; Fructosamine 142. Acute leukemia; elevated potassium 143. Sensitivity of MCV; screen iron deficiency 144. Distribution of the values: 25th percentile 145. NT-proBNP: description 146. Linearity; regression 147. Cholesterol; maximum bias 148. CML in blast crisis; glucose 149. Fasting hypoglycemia; C-peptide 150. Blunt head trauma; distinguishing fluids 151. Canavan disease; mutation in aspartoacylase 152. Fetal fibronectin; preterm labor 153. Nitric oxide; peroxynitric acid 154. BNP; congestive heart failure 155. Drugs of abuse; metabolite of crack cocaine 156. High-sensitivity C-reactive protein; levels of >15 mg/L indicate active inflammation 157. Circulating alkaline phosphatase; condition
Hematopathology 159. Hodgkin’s disease; lymph node excision 160. Plasma cell leukemia; peripheral blood smear 161. Sickle cell disease; hemoglobin electrophoresis patterns 162. Small megakaryocytes; chronic myelogenous leukemia 163. Abetalipoproteinemia; peripheral blood smear 164. Chronic myelomonocytic leukemia; peripheral blood smear 165. Anemia of chronic disease; lymphadenopathy 166. Plasma cell myeloma; WHO 167. Severe neutropenia in the neonatal age; bacterial sepsis 168. chronic myelogenous leukemia; absolute basophilia 169. Chloroacetate esterase; myeloid sarcoma 170. Beta-thalassemia trait; hemoglobin A2 171. Hyperdiploid karyotype; peripheral blood slide 172. Toxoplasmosis; lymph node
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173. 174. 175. 176. 177. 178. 179. 180. 181. 182. 183. 184. 185. 186. 187. 188. 189. 190. 191. 192. 193. 194. 195. 196. 197. 198. 199. 200. 201. 202. 203.
Mantle cell lymphoma; CD5-expression CD15 positive neoplastic cells; slide Monoclonal chronic large granular lymphocyte proliferations; neutropenia Acute lymphoytic leukemia; cytochemical reactions Hairy cell leukemia; tartrate-resistant acid phosphatase Thrombotic thrombocytopenic purpura; platelet count Refractory anemia; peripheral blood smear and laboratory studies S-beta thalassemia; hemoglobin electrophoresis Platelet function; inhibition Bernard-Soulier disease; platelet aggregation study Essential thrombocythemia; platelet count B-cell lymphoma; immunoglobulin Post-transfusion purpura; P1A1 antigen B-cells; Hairy cell leukemia Cold agglutinin disease; red cell finding Alder-Reilly anomaly; mucopolysaccharidoses Thrombotic thrombocytopenic purpura; pathogenesis Factor XII deficiency; bleeding risk Liver disease; coagulation results Viral infection; blood smear shown Osteoblasts; bone marrow smear Chediak-Higashi syndrome; peripheral blood smear Thrombotic thrombocytopenic purpura; blood smear Specimen requirement for CBC; Quality Control Spleen; PAS/diastase stains Mean cell volume (MCV); hyperglycemia nemias Hemolytic Megaloblastic anemia; bone marrow aspirate smear Prothrombin G20210A mutation; predispositions Hereditary bleeding disorder; von Willebrand disease Platelet glycoprotein Ib; von Willebrand factor
Microbiology 204. Coxsackieviruses; persistent viral infection 205. Susceptibility testing; disk selection 206. Listeria; gram positive bacillus 207. Staphylococcus aureus; coagulase test 208. Staphylococcus aureus; colony characterizations 209. Prevotella intermedi; pleural fluid 210. Granulomatous dermatitis; microscopic appearance 211. Anaplasma phagocytophilia; human granulocytic ehrilichiosis (HE) 212. Rickettsia rickettssii; camping trip 213. Staphylococcus aureus; mec A gene 214. FTA-ABS test; Treponema pallidum 215. Streptococcus pyogenes; blood culture slide 216. Enterococcus faecalis; blood culture slide 217. Stool assay; post-antibiotic diarrhea 218. Ascaris lumbricoides; cysticercosis 219. Highly pathogenic; non immunocompromised human hosts 220. Bartonella henselae; cat scratch disease 221. Pneumocococus; erythromycin resistance 222. Mycobacterium tuberculosis; nitrate positive 223. Trichophyton species; infections of hair follicles 224. Penicillin resistant S. pneumoniae; oxacillin disk 225. Parvovirus B19; "fifth's" disease 226. Clostridium difficile toxin assays; hospitalized adult patient 227. Neonate sepsis; blood culture 228. Bovine spongioform encephalopathy; Creutzfeldt-Jacob disease 229. Epstein-Barr virus infection; post-transplant lymphoproliferative disorders 230. Malarial infection; red blood cell morphologic alterations 231. Colonic spirochetosis; identified histologically 232. Toxoplasma encephalitis; multifocal necrotizing lesions
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233. 234. 235. 236. 237. 238. 239. 240.
Cryptococcal meningitis; CSF titers of cryptococcal antigen Cytomegalovirus; Latent infection SARS; Coronavirus West Nile Virus; meningoencephalitis Food-borne infections; screening Anaerobe specimens; synovial fluid Enterobius vermicularis; Cellulose tape preparations Actinomyces israelii; oral surgery
Transfusion Medicine 241. Irradiation of Blood; CMV 242. Red blood cell preservative or; approved shelf life 243. Plasmapheresis for TTP; replacement solution 244. Cord red blood cells; Lea 245. Transfusion records; FDA 246. Dosage; Kidd 247. Gamma irradiation; GVHD 248. Cold-reactive agglutinin; anti-I 249. TRALI; pulmonary edema 250. Autologous donor; Requirements 251. Plasmodium vivax; Fy(a-b-) 252. Transfusion reaction; additional transfusions 253. Platelet pheresis donors; Requirement 254. HLA-identical match; siblings 255. Enzyme treatment; S antigen 256. Donor reaction; treatment is 257. Blood preservation; pH 258. Massively transfused patient; bleeding 259. HIV infections; EIA-detectable antibodies 260. Critical titer of anti-D; amniocentesis 261. TRALI; anti-leukocyte antibodies 262. Leukocyte-reduced Red Blood Cells; cytomegalovirus 263. Infectious mononucleosis; anti-I 264. Massive transfusion; platelet transfusion 265. Donor Collection; additional blood 266. Chronic Transfusion; chelators 267. Anti-K and anti-Fya; Enzyme techniques 268. Malaria; Haiti 269. Antithetical platelet antigens; GPIIIa 270. Rh null phenotype; stomatocytes 271. Plasma products; expiration 272. Bleeding complications; central line placement 273. Anti-M; glycophorin A 274. Apheresis catheter placement; patient management 275. Cryoprecipitate; minimum factor 276. Mislabeled Specimen; RBC unit issue 277. Lewis antibody; first pregnancy 278. Granulocyte transfusion; graft versus host disease 279. T cell depletion; engraftment failure 280. Blood component preparation; order of steps Special Topics Immunopathology 281. Paroxysmal nocturnal hemoglobinuria; Ham's test 282. Immunofluorescence Lupus Band Test; skin 283. IgA molecules; placenta 284. IgA deficiency; Caucasians 285. Severe renal pathology; autoantibody 286. Silicone breast implants; autoimmune disease 287. Bence Jones protein; chemical structure 288. Anti-mitochondrial antibody; symptoms 289. Acute-phase reaction; indicator
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290. 291. 292. 293. 294. 295. 296. 297. 298. 299.
C-reactive protein; pneumoccocal C-polysaccharide Acute-phase reaction; electrophoresis Systemic vasculitis; abnormal serologic test CREST variant of scleroderma; anti-centromere antibody HIV disease Monitoring; CD34 enumeration Acute leukemias; immunophenotypic analysis Hemoglobin F; replacement assay Linear deposition of IgG and C3; Bullous pemphigoid Amyotrophic lateral sclerosis; superoxide dismutase-1 (SOD-1) gene Huntington's chorea; trinucleotide repeat disorder
Laboratory Administration 300. Maslow; highest level 301. Motivation technique; empowerment 302. Accrediting organization; JCAHO 303. CLIA waived tests; FDA review 304. Internet connection; T1 305. Archive hypertext documents; CD-RW 306. Retention of laboratory reports; time requirements 307. Current Procedural Terminology; code for a medical procedure or service 308. Flow chart; symbol 309. Medicare Part B reimbursement; pathologist services 310. Specimen referral; illegal 311. Laboratory employees; Hepatitis B vaccine 312. majority of tests; type of laboratory 313. Medicare; billing notification Special Techniques 314. Flow cytometry; lymphocyte scatter 315. HLA type; disease association 316. Angioimmunoblastic lymphadenopathy; gene rearrangements 317. Mantle cell lymphoma; phenotypic marker 318. Acute myelogenous leukemia; retinoic acid therapy 319. Anaplastic large cell lymphoma; CD30 positivity and t(2;5) translocation 320. Synovial sarcoma; t(X;18)(p11;q11) 321. Fragile X syndrome; trinucleotide expansion disease 322. Hairy cell leukemia; CD11c, CD22, CD25, and CD103 323. Myelodysplastic syndromes; chromosome changes 324. Multiple Endocrine Neoplasia type 2; RET gene 325. Inherited thrombophilia; factor V Leiden mutation
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