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									Material Safety Data Sheet
Section 1. Chemical Product and Company Identification
Common Name Supplier

Bicuculline Methiodide
Pierce Chemical Company P.O. Box 117 Rockford, IL 61105 815.968.0747 Not available. Not available. Not available. Pierce Chemical Company P.O. Box 117 Rockford, IL 61105 815.968.0747

Code MSDS# Validation Date

0020115 1870340 147
8/18/98

Synonym Trade name Material Uses Manufacturer

Print Date

8/19/98

Responsible Name Company
In Case of Emergency

CALL CHEMTREC: 800.424.9300 OUTSIDE US: 202.483.7616

Section 2. Composition and Information on Ingredients
Name CAS # % by Weight Exposure Limits

1) Bicuculline Methiodide

100

Section 3. Hazards Identification
Physical State and Appearance Emergency Overview

Solid. (Powdered solid.)

MAY BE FATAL IF ABSORBED THROUGH SKIN, IF SWALLOWED OR INHALED. MAY CAUSE SEVERE ALLERGIC RESPIRATORY REACTION. MAY BE FATAL IF ABSORBED THROUGH SKIN, IF SWALLOWED OR INHALED. MAY CAUSE SEVERE ALLERGIC RESPIRATORY REACTION. Absorbed through skin. Eye contact. Inhalation. Ingestion.

Routes of Entry Potential Acute Health Effects

Eyes Irritation of the product in case of eye contact: Not available. Skin Irritation of the product in case of skin contact: Not available. Sensitization of the product: Not available. Extremely hazardous in case of skin contact (permeator). Severe over-exposure can result in death. Inhalation Extremely hazardous in case of inhalation, of inhalation (lung sensitizer). May be fatal if inhaled. Ingestion Extremely hazardous in case of ingestion. May be fatal if swallowed.
Potential Chronic Health Effects
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.

Medical Conditions Repeated exposure to an highly toxic material may produce general deterioration of health by an Aggravated by Overexposure accumulation in one or many human organs. Overexposure Not available. /Signs/Symptoms See Toxicological Information (section 11)

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Bicuculline Methiodide Section 4. First Aid Measures
Eye Contact Skin Contact

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NO known EFFECT on eye contact, rinse with water for a few minutes. After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Since the product can readily penetrate the protective epidermal layer and cause rashes or eczema, a good hand cream should be used after washing affected areas. Seek medical attention. Wash contaminated clothing before reusing. Allow the victim to rest in a well ventilated area. Seek immediate medical attention. DO NOT induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Not available.

Inhalation Ingestion

Notes to Physician

Section 5. Fire Fighting Measures
Flammability of the Product Auto-ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Fire Fighting Media and Instructions Protective Clothing (Fire)

May be combustible at high temperature. Not available. Not available. Not available. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). No specific information is available in our database regarding the flammability of this product in presence of various materials. Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. No specific information is available in our database regarding the product's risks of explosion in the presence of various materials. SMALL FIRE: Use DRY chemicals, CO2, water spray or foam. LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. Wear MSHA/NIOSH approved self-contained breathing apparatus or equivalent and full protective gear. No additional remark. No additional remark.

Special Remarks on Fire Hazards Special Remarks on Explosion Hazards

Section 6. Accidental Release Measures
Small Spill and Leak Large Spill and Leak

Use appropriate tools to put the spilled solid in a convenient waste disposal container. Our database contains no additional information in case of a spill and/or a leak of the product. Use a shovel to put the material into a convenient waste disposal container.

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Bicuculline Methiodide Section 7. Handling and Storage
Handling Storage

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Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate locked safety storage cabinet or room.

Section 8. Exposure Controls/Personal Protection
Engineering Controls

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Eyes Safety glasses. Body Lab coat.

Personal Protection

Respiratory Vapor and dust respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Hands Gloves. Feet Not applicable.
Protective Clothing (Pictograms)

Personal Protection in Case of Splash goggles. Full suit. Vapor and dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not a Large Spill be sufficient; consult a specialist BEFORE handling this product. Product Name
1) Bicuculline Methiodide

Exposure Limits

Consult local authorities for acceptable exposure limits.

Section 9. Physical and Chemical Properties
Physical State and Appearance Molecular Weight Molecular Formula pH (1% Soln/Water) Boiling/Condensation Point Melting/Freezing Point Critical Temperature Specific Gravity Vapor Pressure Vapor Density Volatility Odor Threshold Evaporation Rate

Solid. (Powdered solid.) 509.29 g/mole C21 H20 N O6 I Not available. Not available. 202°C (395.6°F) Not available. Not available. Not available. Not available. Not available. Not available. Not available.

Odor Taste Color

Not available. Not available. White.

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Bicuculline Methiodide
VOC Viscosity LogKow Ionicity (in Water) Dispersion Properties Solubility

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Not available. Not available. Not available. Not available. Not available. Not available.

Physical Chemical Comments No additional remark.

Section 10. Stability and Reactivity
Stability and Reactivity Conditions of Instability

The product is stable. No additional remark.

Incompatibility with Various Reactive with moisture. Substances Hazardous Decomposition Products Hazardous Polymerization

Not available. No.

Section 11. Toxicological Information
Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans

LD50: Not available. LC50: Not available. Not available. Extremely hazardous in case of skin contact (permeator), of ingestion, of inhalation.

Special Remarks on Toxicity No additional remark. to Animals Special Remarks on Chronic Effects on Humans Special Remarks on Other Toxic Effects on Humans

No additional remark. To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated.

Section 12. Ecological Information
Ecotoxicity BOD5 and COD Biodegradable/OECD Mobility

Not available. Not available. Not available. Not available. Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation Special Remarks on the Products of Biodegradation

The products of degradation are less toxic than the product itself. No additional remark.

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Bicuculline Methiodide Section 13. Disposal Considerations
Waste Information Waste Stream

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Not available. Not available.

Consult your local or regional authorities.

Section 14. Transport Information
DOT Classification

Not a DOT controlled material (United States).

Not applicable.

Not available.
Marine Pollutant

Not available.

Hazardous Substances Reportable Quantity Special Provisions for Transport TDG Classification ADR/RID Classification IMO/IMDG Classification ICAO/IATA Classification

Not available. No additional remark. Not a TDG controlled material. Not controlled under ADR of the EEC. Not controlled under IMDG. Not controlled under IATA.

Section 15. Regulatory Information
HCS Classification U.S. Federal Regulations

HCS CLASS: Highly toxic. TSCA inventory: No products were found.

Clean water act (CWA) 307: No products were found. Clean water act (CWA) 311: No products were found. Clean air act (CAA) 112 accidental release prevention: No products were found. Clean air act (CAA) 112 regulated flammable substances: No products were found. Clean air act (CAA) 112 regulated toxic substances: No products were found.
International Regulations WHMIS (Canada)

WHMIS CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). No products were found.

EINECS DSCL (EEC) International Lists State Regulations

Not available. Not controlled under DSCL (Europe). No products were found. No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: No products were found.

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Bicuculline Methiodide Section 16. Other Information
Label requirements

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MAY BE FATAL IF ABSORBED THROUGH SKIN, IF SWALLOWED OR INHALED. MAY CAUSE SEVERE ALLERGIC RESPIRATORY REACTION.
Health Fire Hazard Reactivity Personal Protection

Hazardous Material Information System (U.S.A.)

3 National Fire 0 Protection 0 Association (U.S.A.) a

0
Health

Fire Hazard

3

0

Reactivity Specific Hazard

References Other Special Considerations

Not available. No additional remark.
Verified by Company. Printed 8/19/98.

Validated by Company on 8/18/98. CALL CHEMTREC: 800.424.9300 OUTSIDE US: 202.483.7616 Notice to Reader

To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.


								
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