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EpiZyme, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile

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EpiZyme, Inc. (Epizyme) is a biopharmaceutical company, based in the US. The company discovers and develops novel, molecular targeted drugs for the treatment of oncology and metabolic diseases. Its products include DOT1L and EZH2. EpiZyme’s product, DOT1L is used in the treatment of leukemia and EZH2 is used in the treatment of lymphoma and breast cancer. The company’s biochemical technology platform provides HMT activity assay format with screen multiple representatives of HMT family. These small molecule inhibitors of HMTs are used for the treatment of various metabolic diseases. It partners with Celgene, GlaxoSmithKline, Eisai, The Leukemia & Lymphoma Society and Multiple Myeloma Research Foundation. EpiZyme is headquartered in Cambridge, Massachusetts, the US.

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									          EpiZyme, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile
       Reference Code: GDPH194377D                                                                                                           Publication Date: JAN 2013

      Company Overview                                                                                        Key Facts
      EpiZyme, Inc. (Epizyme) is a biopharmaceutical company, based in the US. The
                                                                                                              EpiZyme, Inc., Pharmaceuticals & Healthcare, Key
      company discovers and develops novel, molecular targeted drugs for the treatment
                                                                                                              Facts
      of oncology and metabolic diseases. Its products include DOT1L and EZH2.
      EpiZyme’s product, DOT1L is used in the treatment of leukemia and EZH2 is used in                        Web Address                      www.epizyme.com
      the treatment of lymphoma and breast cancer. The company’s biochemical
                                                                                                               Revenue (US$ million)                           NA
      technology platform provides HMT activity assay format with screen multiple
      representatives of HMT family. These small molecule inhibitors of HMTs are used                          Number of Employees                             NA
      for the treatment of various metabolic diseases.                                                         GlobalData

      Financial Deals Landscape
        EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals by Type,                       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By
        2007 to YTD 2013                                                                  Year, 2007 to YTD 2013


                                                                                                                                                3
                                                                                                          3




                                                                                           No. of Deals
                                                                                                          2

                                                                                                                          1         1                    1
                                                                                                          1

                                                                                                                 0                       0                         0
                                                                                                          0
                                                                                                               2007      2008   2009    2010   2011     2012   YTD
                                                                                                                                                               2013


                                                                                          Note: Deals include all announced pharmaceuticals & healthcare deals
         Note: Deals include all announced pharmaceuticals & healthcare deals from
                                                                                          from 2006 onwards, GlobalData
         2006 onwards, GlobalData


         EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By                            EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By
         Region, 2007 to YTD 2013                                                         Therapy Area, 2007 to YTD 2013

                         8                                                                                8
                               6
          No. of Deals




                                                                                                                     6
                                                                                           No. of Deals




                         6                                                                                6
                         4              3         3        3         3
                                                                                                          4
                         2                                                                                                      2        2          2          2
                                                                                                          2
                         0
                             North    Asia-     Europe   Middle   South                                   0
                             Americ   Pacific             East     and                                          Oncolo Cardiov Central          Immun Metabol
                               a                          and     Central                                         gy   ascular Nervou            ology    ic
                                                         Africa   Americ                                                         s                     Disorde
                                                                    a                                                          System                     rs



         Note: Deals include all announced pharmaceuticals & healthcare deals             Note: Deals include all announced pharmaceuticals & healthcare deals
         from 2006 onwards, GlobalData                                                    from 2006 onwards, GlobalData




EpiZyme, Inc. - Pharmaceuticals & Healthcare - Deals and                                                                                       Reference Code: GDPH194377D
Alliances Profile
Source : www.globalcompanyintelligence.com                                                                                                                                Page 1
© GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form
       Table of Contents
       Table of Contents ............................................................................................................................................................................... 2
          List of Tables .................................................................................................................................................................................. 3
          List of Figures ................................................................................................................................................................................. 3
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Year, 2007 to YTD 2013............................................................................ 3
       EpiZyme, Inc., Pharmaceuticals & Healthcare Deals By Type, 2007 to YTD 2013 ............................................................................ 5
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Region, 2007 to YTD 2013 ........................................................................ 6
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Therapy Area, 2007 to YTD 2013 ............................................................. 7
       EpiZyme, Inc., Medical Devices Deals, 2007 to YTD 2013 ................................................................................................................ 8
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals Summary, 2007 to YTD 2013 ......................................................................... 9
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deal Details ............................................................................................................ 10
          Venture Financing......................................................................................................................................................................... 10
             Epizyme Secures Additional $8 Million In Series B Financing Round ....................................................................................... 10
             EpiZyme Secures $14 Million In Series A Financing ................................................................................................................. 12
          Partnerships.................................................................................................................................................................................. 13
             Epizyme, Eisai And Roche Enter Into Co-Development Agreement For Companion Diagnostic Test ...................................... 13
             Leukemia & Lymphoma Society Enters Into An Agreement With EpiZyme............................................................................... 15
             EpiZyme Enters Into Co-Development Agreement With Eisai................................................................................................... 17
             Epizyme Enters Into Co-Development Agreement With GlaxoSmithKline ................................................................................ 18
          Licensing Agreements .................................................................................................................................................................. 19
             Epizyme Announces Licensing Agreement With Celgene For HMT Inhibitor Programs ........................................................... 19
       EpiZyme, Inc. - Key Competitors ...................................................................................................................................................... 20
       Key Employees ................................................................................................................................................................................ 21
       Locations And Subsidiaries .............................................................................................................................................................. 22
          Head Office ................................................................................................................................................................................... 22
       Appendix .......................................................................................................................................................................................... 23
          Methodology ................................................................................................................................................................................. 23
          About GlobalData ......................................................................................................................................................................... 23
          Contact Us .................................................................................................................................................................................... 23
          Disclaimer ..................................................................................................................................................................................... 23




EpiZyme, Inc. - Pharmaceuticals & Healthcare - Deals and                                                                                                         Reference Code: GDPH194377D
Alliances Profile
Source : www.globalcompanyintelligence.com                                                                                                                                                                Page 2
© GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form
       List of Tables
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Key Facts.................................................................................................................. 1
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Year, 2007 to YTD 2013............................................................................ 1
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Region, 2007 to YTD 2013 ........................................................................ 1
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Therapy Area, 2007 to YTD 2013 ............................................................. 1
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Year, 2007 to YTD 2013............................................................................ 4
       EpiZyme, Inc., Pharmaceuticals & Healthcare Deals By Type, 2007 to YTD 2013 ............................................................................ 5
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals By Region, 2007 to YTD 2013 ........................................................................ 6
       EpiZyme, Inc., Deals By Therapy Area, 2007 to YTD 2013................................................................................................................ 7
       EpiZyme, Inc., Medical Devices Deals, 2007 to YTD 2013 ................................................................................................................ 8
       EpiZyme, Inc., Pharmaceuticals & Healthcare, Deals Summary, 2007 to YTD 2013 ......................................................................... 9
       Epizyme Secures Additional $8 Million In Series B Financing Round .............................................................................................. 10
       EpiZyme Secure
								
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