Application pack by 0k15667O


									Application pack

Research Associate

Diabetes and Nutritional Sciences Division


Reference Number: R6/MEN/1007/12-JE

 Explanatory notes, including application procedure.
 Further particulars, including:
 • Information about King’s College London, and the post;
 • Job description;
 • Person specification;
 • Summary of the terms and conditions of service.
Explanatory notes
Please read carefully before completing the application form
Thank you for your enquiry regarding a post at King’s College London. Enclosed is a set of further
particulars for this post. These comprise: a job description and person specification; general
information about the College, School and Department; as well as the main terms and conditions of
the post.

Application procedure
Should you wish to apply for this position, please send the following:

 Please complete a Personal details form and Equal opportunities monitoring form (CTRL + click
  the link)

 a copy of a short statement setting out your reasons for applying for the post and highlighting the
  particular skill and experience which you feel you would bring to the role

 a copy of a current curriculum vitae, which should include inter alia:
  • your full name with title
  • details of your present post with date of appointment
  • education
    - degrees (subject, class, institution, date of award)
    - other academic/professional qualifications (subject, level, institution, date of award)
    - distinctions other than degrees
  • membership of professional and learned societies
  • teaching and research experience
  • administrative and management experience
  • grants obtained
  • publications

To email:

Applications should be made electronically in Word or PDF format.

Please ensure you quote reference number R6/MEN/1007/12-JE on all correspondence.

Informal enquiries may be made to Dr. Wolfgang Maret via email at

Closing date: 26 October 2012

Please advise your referees that they may be contacted and asked to provide a reference at short

Page 2
Equal opportunities
King's College London recognises that equality of opportunity and the recognition and promotion of
diversity are integral to its academic and economic strengths.The following principles apply in respect
of the College’s commitment to equality and diversity:
 To provide and promote equality of opportunity in all areas of its work and activity;
 To recognise and develop the diversity of skills and talent within its current and potential
 To ensure that all College members and prospective members are treated solely on the basis of their
  merits, abilities and potential without receiving any unjustified discrimination or unfavourable
  treatment on grounds such as age, disability, marital status, pregnancy or maternity, race, religion
  or belief, sex, sexual orientation, trans status, socio-economic status or any other irrelevant
 To provide and promote a positive working, learning, and social environment which is free from
  prejudice, discrimination and any forms of harassment, bullying or victimisation;
 To promote good relations between individuals from different groups.

Applicants with disabilities
King's College London is keen to increase the number of disabled people it employs. We therefore
encourage applications from individuals with a disability who are able to carry out the duties of the
post. If you have special needs in relation to your application please contact the Human Resources
Advisor responsible for the administration of the post.

Travel expenses
The College normally reimburses reasonable travel costs to and from interview within the United
Kingdom. Regrettably, only limited contribution to travel costs for applicants from outside the UK
may be available. Please contact the Head of Department before making your reservation.

We very much regret that due to limited resources and the large number of applications we currently
receive, we are only able to inform short listed candidates of the outcome of their application.
  If you do not hear from us within four weeks of the closing date, please assume that you have been
unsuccessful on this occasion. We would like to assure you, however, that every application we receive
is considered in detail and a shortlist only drawn up after careful reference to a detailed person
  If therefore, your application is not successful, we hope that you will not be discouraged and will
still apply for other suitable vacancies at King’s College London as and when they are advertised.

Thank you for your interest in King’s College London.

                                                                                                  Page 3
Further particulars
The College
King’s College London is one of the top 30 universities in the world (2011/2012 QS international
world rankings), the Sunday Times 'University of the Year 2010/11' and the fourth oldest in England.
A research-led university based in the heart of London, it has nearly 23,500 students (of whom nearly
9,000 are graduate students) from 150 countries and approximately 6,000 employees.
  King’s has an outstanding reputation for providing world-class teaching and cutting-edge research.
In the 2008 Research Assessment Exercise for British universities, 23 departments were ranked in
the top quartile of British universities; over half of our academic staff work in departments that are in
the top 10 per cent in the UK in their field and can thus be classed as world leading. The College is in
the top seven UK universities for research earnings and has an overall annual income of nearly £525

There are nine Schools of Study:
 Arts & Humanities
 Biomedical Sciences
 Dental Institute
 Institute of Psychiatry
 Law
 Medicine
 Natural &Mathematical Sciences
 FlorenceNightingaleSchool of Nursing & Midwifery
 Social Science & Public Policy

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a
wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences
including international affairs. It has played a major role in many of the advances that have shaped
modern life, such as the discovery of the structure of DNA and research that led to the development of
radio, television, mobile phones and radar. It is the largest centre for the education of healthcare
professionals in Europe; no university has more Medical Research Council Centres.
  King's College London, Guy's and St Thomas' NHS Foundation Trust (GSTT), King's College
Hospital NHS Foundation Trust (KCH) and South London and Maudsley NHS Foundation Trust
(SLaM) are part of the King's Health Partners Academic Health Sciences Centre, a pioneering global
collaboration between one of the world's leading research-led universities and three of London's most
successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental
health services. Accredited by the Department of Health in 2009, King’s Health Partners (KHP) is one
of five academic health science centres in the UK. The four sovereign partner organisations within
KHP are committed to working cooperatively to create an internationally recognised centre of
excellence which draws upon academic expertise in medical science, basic science, social science, law
and humanities and brings together world leading research, education and clinical training and
practice within an integrated environment. KHP hosts two National Institute for Health Research
(NIHR) funded Biomedical Research Centres (BRCs) and a NIHR funded Biomedical Research Unit
in Dementia through local KCL-GSTT and KCL-SLaM partnerships respectively. These NIHR centres
and unit are specifically focused on enhancing the NHS clinical research environment, in order to
accelerate the pace of translation of basic discovery science into experimental medicine and early
phase clinical research and thus speed up the delivery of new treatments and diagnostics for patient
benefit. For more information about King’s Health Partners, visit:

The School
The School of Medicine is one of the largest medical schools in the UK and is committed to pursuing excellence
in research and teaching. The School of Medicine has a population of over 2000 undergraduate and
postgraduate students. The School consists of 9 cross-School research divisions populated by over 600 staff,
with a research income of over £32M.

Page 4
The School is located across four hospital campuses in South London. Each campus has its own distinctive
character and this diversity is an attractive feature of the School for our staff and students, particularly
undergraduates. The School’s two major partner trusts, Guy’s and St Thomas’ NHS Foundation Trust (GST)
and King’s College Hospital NHS Foundation Trust (KCH) have 1,000,000 patient contacts a year combined.
Their specialist services include cancer, cardiothoracic, renal, haematology, children’s services, liver disease
and transplantation, foetal medicine and neuroscience.

Based on UCAS application figures, King’s College London continues to be the most popular choice for
undergraduate medicine in the UK. The School also has a vibrant postgraduate community encompassing
taught and research degrees, with around 400 students.

The School’s research profile has benefited from significant investment since 2001, in staff and infrastructure,
further enhancing King’s international reputation in biomedical research. King’s is ranked fourth nationally in
terms of MRC application success rate by percentage of grants awarded, and in 2006 was one of six
universities selected by the MRC to sign a Strategic Partnership Agreement. King's has also been successful in
joint bids with its partner NHS Trusts for Department of Health Research Centres of Excellence, and the
College joined the global elite in medical research as part of a Global Medical Excellence Cluster.

The investment programme has included the £7M committed to laboratories to support the School’s infection
and immunity programme, and significant investment at St Thomas’ in newly refurbished laboratories for the
integrated, cross-disciplinary Imaging Sciences Division. The £30m James Black Centre opened in 2007 at the
Denmark Hill Campus provides an international centre focussed on cardiovascular research, organ
transplantation and neurodegenerative disease. An Institute of Clinical Neurosciences has also been
established on the campus, to co-exist alongside the Trust neuroscience clinical service.

The Division
The Diabetes and Nutritional Sciences Division consists of 35 academic staff and is lead jointly by
Professor Stephanie Amiel (RD Lawrence Professor of Diabetic Medicine) and Professor Tom Sanders
(Professor of Nutrition & Dietetics). The line management of staff and resource allocation is managed
by the Division which is well supported by administrative staff. The Division of Diabetes & Nutritional
Sciences, brings together basic scientists, clinicians and public health practitioners in the two
disciplines to develop evidence based strategies for prevention of diet related and metabolic disease,
and to translate findings from basic science to improve their clinical management. We maintain
strong collaborative links across the King’s College Health Schools and our research is integral to the
aims and objectives of the Diabetes, Endocrinology and Metabolism, Nutrition, Obesity, Vision and
Related Surgeries (DENOVaR) Clinical Academic Group within King's Health Partners. The overall
strategy of the AHSC is to translate new research finding into clinical practice and to improve the
delivery of health care.

The Division was returned under Subjects Allied to Medicine and achieve the highest score in the
Unit of Assessment with 30% 4* and 35% 3* ( the top two categories of excellence). Research in the
Nutrition Section is focused on Biometals, Diet and Gastrointestinal Health and Diet and
Cardiovascular Health. The Nutrition Section currently has 24 principal investigators, 14 research
assistants and fellows and 30 PhD/MD students.

The Nutritional Sciences section has research facilities located in the Franklin-Wilkins Building but
also has access to the Clinical Research Facility at St Thomas’ Hospital. Facilities exists for
conducting human metabolic feeding studies and the laboratories are modern and well equipped and
are managed by a Divisional Resource Manager. Within the Franklin-Wilkins Building there is a Mass
Spectroscopy facility and a Genomic Centre. The College also has access to excellent imaging

                                                                                                            Page 5
The Post
The zinc(II) ion is a cellular signalling substance. Disruption of its cellular regulation is involved in
several high-profile diseases, including diabetes, cancer and Alzheimer’s disease. We have identified
protein tyrosine phosphatases (PTP) as key targets for zinc(II) ion signals. The BBSRC has funded a
project to investigate which PTPs are zinc(II)-regulated, to determine the structure of the regulatory
site, and to address physiological significance in cultured cells. The results are expected to
demonstrate a novel biological control of signalling cascades involving biological phosphorylations. A
post-doctoral research associate will be appointed to carry out this three-year project. The successful
candidate will be placed within the Diabetes & Nutritional Sciences Division at the Franklin-Wilkins
Building, Waterloo campus of King’s College London. For informal enquiries, please contact Dr.
Wolfgang Maret.

Page 6
Job description
Post title                             Research Associate

Department/Division/Directorate Diabetes and Nutritional Sciences Division, School of Medicine

Grade                                  6

Responsible for                        n/a

Responsible to                         Professor Tom Sanders

Role purpose

The post-holder will be responsible for the execution of the BBSRC funded project to characterise the
role of zinc(II) ions in the regulation of cell signalling pathways through inhibition of protein tyrosine

Role outline - main responsibilities

Key objectives
 Perform research into the role of zinc(II) ions in the regulation of cell signalling pathways through inhibition
  of protein tyrosine phosphatases.
 Order reagents required for the research project and participate in general laboratory cleaning and
 Demonstrate and explain techniques to other members of the laboratory.
 Monitor the non-pay expenditure on the grant.
 Present relevant research papers in the field at group meetings.
 Attend seminars in the Nutritional Sciences Division and other relevant seminars and meetings, both
  internal and external to the College.
 Write reports and manuscripts on the research.
 Present results and progress reports at relevant internal and external meetings

Communication & networking
 Communicate effectively with the principal investigator, co-investigator and other scientists involved in the
 Write up results of own research on a day-to-day basis
 Contribute to the production of research reports
 Present information on research progress and outcomes at research meetings
 Liaise with internal and external research colleagues and support staff on routine matters
 Make internal and external contacts to develop knowledge and understanding and form relationships for
  future collaboration

Decision making, planning & problem solving
   Plan own day-to-day research activity within the framework of the agreed programme
   Contribute to the planning of research projects
   Contribute to decisions affecting the work of the team
   Deal with problems which may affect the achievement of research objectives and deadlines
   Make use of standard research techniques and methods
   Co-ordinate own work with that of others to avoid conflict or duplication of effort

                                                                                                             Page 7
Service delivery
Be able to
 Liaise with the principal investigator and co-investigator on all aspects of service provision and development.
 Work autonomously within division operating procedures and protocols.
 Adhere to local laboratory-based and safety policies.

Analysis & research
 Undertake research in line with the objectives defined in the research proposal
 Conduct literature and database searches and critically evaluate the results
 Continue to update knowledge and develop and acquire new skills

Team work, teaching & learning support
 Actively participate as a member of a research team
 Attend and contribute to relevant meetings, including seminars in the Diabetes & Nutritional Sciences
 Assist in the supervision and assessment of student projects

Sensory/physical demands & work environment
 Carry out tasks that require the learning of certain skills
 Required to assess and to be aware of the risks in the work environment

Specific Aspects - indicate frequency D (daily), W (weekly), M (monthly) where
 Intensive Display Screen Equipment work         W     Direct patient contact involving exposure prone       n/a
 (eg. data entry or digital microscopy):               procedures (EPP):

 Heavy manual handling:                          n/a   Direct patient contact, no EPP                        n/a

 Highly repetitive tasks (eg. pipetting or re-   D     Work with patient specimens (eg. blood or tissue      n/a
 shelving books):                                      samples):

 Shift work, night work or call-out duties:      n/a   Work with GM organisms or biological agents           D
                                                       that may pose a hazard to human health:

 Work involving risk of exposure to              n/a   Hazards which require health surveillance eg.         n/a
 environmental or human pathogens (eg in               respiratory sensitisers (allergens, substances with
 waste streams or soils):                              risk phrase R42, wood dust etc) or loud noise:

 Driving vehicles on College business:           n/a   Food handling or preparation:                         n/a

 Work at height (eg. ladders, scaffolds etc)     n/a   Work in confined spaces (eg. sump rooms, etc)         n/a

Pastoral care
 Show consideration to others

Page 8
Organisational chart

                       Diabetes and Nutritional Sciences Division
                         (Jnt Heads Prof Amiel / Prof Sanders)

           Diabetes Research Group                   Nutrition Research Group
              (Head Prof Amiel)                        (Head Prof Sanders)

                             Diet & Cardiovascular         Diet & Gastrointestinal    Metal Metabolism
                             Health Research Group         Health Research Group       Research Group
                              (Head Prof Sanders)           (Head Prof Sanders)      (Head Prof Sanders)

                                                                                      Current Position

Special requirements
 You may be required to work irregular hours in accordance with the needs of the role.
 Information of a confidential nature must be kept strictly confidential and should never be
  disclosed either inside or outside work. It should be noted that breach of confidentiality is a serious
  offence which may lead to dismissal.
 This appointment is subject to Occupational Health clearance. Should you be offered this post you
  will be sent an Occupational Health Questionnaire along with your contract of employment. When
  the Occupational Health Department have evaluated your questionnaire and declared that you are
  fit for appointment, your appointment will be formally confirmed.

All staff are expected to adhere to King’s policies and procedures.

Date 02 October 2012

Please note
This job description reflects the core activities of the role and as the College and the post-holder
develop there will inevitably be changes in the emphasis of duties. It is expected that the post-holder
recognise this and adopt a flexible approach to work and be willing to participate in training.
  If changes to the job become significant, the job description should be reviewed formally by the
post-holder and line manger. The Human Resources department should then be consulted as to the
implications of the proposed changes.

                                                                                                           Page 9
Person specification
                                                                         E       D
Criteria                                                                 S       E
                                                                                     HOW IDENTIFIED
                                                                                     AND ASSESSED
                                                                         S       S
                                                                         E       I   AP     Application
                                                                         N       R
                                                                         T       A
                                                                                     AS     Assessment
                                                                         I       B   I      Interview
                                                                         A       L   P      Presentation
                                                                         L       E   R      References

Education/qualification and training
BSc or MSc in Biochemistry or a related area                             x           AP
PhD in Biochemistry or in a closely related                              x           AP
Proficiency in using Microsoft Word, Excel, email, internet, and         x
                                                                                     AP, I, R
other academic research-related software, e.g. SPSS, Endnote
Good understanding of protein chemistry                                  x           AP, I, R
Good understanding of cell signalling                                    x           AP, I, R
Understanding of principles of biometals                                         x   AP, I, R
Supervision and teaching of other researchers                                    x   AP, I, R
Working independently on a research project                              x           AP, I, R
Working as part of a research team                                       x           AP, I, R
Ability to write reports and manuscripts in English                      x           AP, I, R
Ability to present results in seminars and meetings                      x           AP, I, R
Managing an independent research project                             x               AP, I, R
Experience of cell culture and common biomolecular techniques        x               AP, I, R
Management of data and statistical analysis                          x               AP, I, R
Managing an independent research project                                     x       AP, I, R
Personal characteristics/other requirements
Ability to interact well with colleagues and members of the public       x           I, R
Good time management skills                                              x           I, R
Ability to take initiative to solve technical problems                   x           I, R

Page 10
Summary of terms and conditions of service
This appointment is made under the King’s College London Terms and Conditions of Service for Non-
Clinical Research staff, a copy of which is available from the Human Resources department on

Period of Appointment      Fixed-term contract for 36 months

Probation                  6 months

Salary                     £31,020 per annum, plus £2,323 London Allowance per annum

Annual leave               27 working days. Staff receive four additional closure days. Notification as
                           to how these days are taken is circulated at the start of the academic year.

This appointment is superannuable under the USS pension scheme. Staff already superannuated
under the NHS Superannuation Scheme may opt to remain in that scheme provided an application to
do so is received by the NHS scheme trustees within three months of appointment to King’s College
London. Alternatively staff may opt to participate in SERPS or take out a personal pension. Please
note that the College does not provide an employer's contribution towards a private pension plan.
  The College operates PensionsPlus by which individuals increase their take home pay by reducing
their NI contributions. Staff who jointhe USS pension scheme will automatically be entered into
PensionsPlus (provided you would benefit from doing so). As a result your salary will be reduced so
that you receive the PensionsPlus salary and a payment is made into your pension scheme instead.
  NB - NHS Superannuation Scheme: Medical Schools are classed as “Direction Employers” and
some benefits of the NHS Scheme are not available to Direction members.
  For further information please contact Ms Pauline Job, Payroll & Pensions Manager, King’s College
London, James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA.

All appointments to King’s are subject to Occupational Health clearance. Should you be offered this
post you will be sent an Occupational Health Questionnaire along with your contract of employment.
When the Occupational Health Department have evaluated your questionnaire and declared that you
are fit for appointment, your appointment will be formally confirmed.

In the course of your work you may have access to personal or confidential information which must
not be disclosed or made available to any other person unless in the performance of your duties or
with specific permission from your Head of School/Department/Division. (In particular if your work
involves the handling of clinical samples and/or patient data, NHS policies for the maintenance of
security and confidentiality of NHS systems and data must be observed). Breaches in confidentiality
may lead to disciplinary action.

Training and Education
King’s College London recognises the importance of training in achieving its objective of pursuing
excellence in teaching, research and clinical practice through the activities of its staff. We are
committed to providing training for all members of staff so that they can perform their jobs effectively
and offering them opportunities for further development. Most training and development will occur
"on the job" and formal training opportunities are also available within King’s College London
associated hospitals trusts and through other external organisations.
  All members of staff with teaching responsibilities are encouraged to obtain formal recognition of
their professional expertise in teaching. It is the normal expectation that staff new to teaching in
higher education will register for the Post Graduate Certificate in Academic Practice (PGCAP) unless

                                                                                                  Page 11
they already possess a teaching qualification in higher education. The PGCAP is taught and managed
by the King's Learning Institute (KLI); information about the certificate and other programmes run
by KLI can be found in their web site

No Smoking Policy
King’s College London is committed to maintaining a healthy environment for staff, students and
visitors. Therefore, please note that smoking is not permitted in any of the College buildings or in
College vehicles. Smoking is also not permitted immediately outside the entrances to College
buildings or near to windows and air intake units. Staff working at associated NHS trust sites or other
premises should adhere to whatever policy is in place at these locations.

Page 12

To top