Med Safety V3 N1

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							                                                                                                    UNIVERSITYOFWASHINGTON
                                                                                                    MEDICAL CENTER
                                                                                                            UW Medicine



          MED SAFETY NEWSLETTER
   AUGUST 2007                                                                                   VOLUME 3, ISSUE 1


Revised PCA Order Sets
The Patient Controlled Analgesia (PCA) order sets                   sedation scores ≥2. Alterations are NOT permitted
have been revised to incorporate key safety                         on the primary care service PCA orders. ALL
strategies with the use of PCA. A signature line has                current orders for opioids and benzodiazepines are
been added for nursing to document the completion                   to be discontinued when a patient is started on a
of an independent double check upon initiation of a                 primary care service PCA. If APS is managing the
PCA order, a change in medication or a change in                    PCA, all orders for other opioids or
drug concentration. The use of a separate MAR                       benzodiazepines must be approved by APS. During
form has been implemented to insure access to the                   PCA, only the PRN medications listed on the PCA
most current PCA order. The sedation score for                      order sets are to be used to manage side effects.
notification of physicians has been changed to

Patches: What you can’t see can harm patients
Medication errors have been reported involving                      fatal overdoses when temperature elevations have
transdermal patch delivery systems and have been                    increased medication release from the system.
associated with patient harm, including death.                      Exposure of the patch application site to external
Several variables provide opportunities for error.                  heat sources such as heating pads, electric blankets,
Before applying a new transdermal patch, be sure to                 and heat lamps should be avoided. Occluding
remove the existing patch because medication often                  dressings, such as TegadermTM, may also cause a
remains available in the patch even after its                       temperature increase and therefore, should not be
recommended duration of use. Few people are                         used to assist in adhering transdermal patches to the
aware that medication patches should be removed                     application site. Accidental ingestion of trandermal
prior to an MRI.       Some patches contain an                      patches has been reported due to improper disposal.
aluminized backing that can create an electrical                    Patches should be disposed of by folding the
current during an MRI and cause burns resulting in                  adhesive sides together and placing in the sharps
tissue damage. At UWMC patients are screened                        container. (See the Administration of Medications
before undergoing an MRI for the presence of                        policy in the nursing policy and procedures).
medication patches. Patches have been linked with

Anticoagulation Services is on the Web!
Looking for the most recent guidelines for the                      these questions and more can be found on the
prevention or treatment of thromboembolism?                         Anticoagulation       Services    website       at
Wondering when it is safe to anticoagulate your                     http://www.uwmcacc.org. This website is also
patient who has an epidural? Trying to manage a                     conveniently linked through the Medical Staff and
patient    with   suspected    heparin   induced                    Patient Care Services websites. It will soon be
thrombocytopenia? Does your patient need a                          added to the Clinical Toolkit as well.
warfarin teaching booklet in Russian? Answers to

                                     Risk Management/Quality Improvement Work Product
                                                Do Not Place In Medical Record
                                     Confidential Pursuant to Rcw4.24.240-250 & 70.41.200
    Report
                                Smart Pumps Are Not Smart on Their Own
                                Incorrectly programming IV pumps is one                         Infusion. Careful attention should be
   Medication
                                of the most common types of medication                          made to the alerts that arise.    If a soft
   Errors and
                                error. IV infusion devices with smart                           guardrail alert occurs, the pump should be
  Adverse Drug
                                pump technology have dose checking                              checked for a programming error and the
   Reactions!
                                capabilities to warn clinicians about                           clinician should verify that the clinical
                                potentially unsafe drug therapy. UWMC                           condition requires higher or lower than
                                implemented the Alaris Smart Pump®                              usual doses. Hard limit alerts require the
                                Infusion System on May 22, 2007. This                           pump to be reprogrammed as it is NOT
                                technology can only avert potentially                           appropriate to exceed these limits. If you
Patient Safety Net              harmful infusion-related medication errors                      encounter a condition that encourages
                                if used properly. Medications should                            bypassing the dose-checking feature,
 A convenient,                  ALWAYS be infused through the                                   please contact your LPC or Unit Manager.
web-based system                GUARDRAILS rather than as a basic
  for Incident
   Reporting                    Drug Name Confusion
                                Confusion resulting from look-alike and                         the Safe Medication Practices Committee
***************
                                sound-alike drug names and look-alike                           maintains a list of drugs with potential for
 Allergy Hotline
                                product packaging can result in potentially                     name confusion and updates this list
    598-0333
                                harmful medication errors. At UWMC,                             annually (see Table).
***************
                                              UWMC Look-alike / Sound-alike Drug List
                                              Clonidine (Catapres®) – Clonazepam (Klonopin®)
 Upcoming topics
                                              Cisplatin – Carboplatin
 HIT Guidelines                               Celecoxib (Celebrex®) – Citalopram (Celexa®) – Fosphenytoin (Cerebyx®)
 Do NOT Crush!                                Doxorubicin liposomal – Doxorubicin
                                              Daunorubicin liposomal – Daunorubicin
 Opioid Potency
                                              Epinephrine - Ephedrine
                                              Hydroxyzine – Hydralazine
                                              Human insulin (Humulin®) – Insulin lispro (Humalog®)
                                              Insulin lispro (Humalog®) – Insulin aspart (Novolog®)
                                              Metformin – Metronidazole
                                              Morphine oral liquid – Morphine concentrate (Roxanol®)
                                              Morphine – Hydromorphone (Dilaudid®)
                                              Oxycodone controlled-release (OxyContin®) – oxycodone
 Do you have ideas for                        Paclitaxel (Taxol®) – Docetaxel (Taxotere®)
future topics you’d like                      Vinblastine – Vincristine – Vinorelbine
   to see in the Med
 Safety newsletter? If
   so, contact Jackie           What’s new from the Institute of Safe Medication Practices?
   Biery, Medication            HydromorPHONE alert                                        Dangerous Heparin-Insulin Confusion
  Safety Pharmacist at          Four deaths occurred after patients received a bolus       Three states have reported the accidental addition
 jsuper@u.washington.edu        dose of 2-4mg of hydromorPHONE, with repeated              of insulin to infant TPNs instead of heparin. A
                                doses of 1-4mg. Contributing factors to these              verbal order to resume an insulin drip was
    The Medication Safety       incidents include: lack of practitioner awareness of       transcribed as “resume heparin drip”. A patient’s
   Newsletter is published      what constitutes an equianalgesic dose of                  central line was flushed with insulin instead of
     quarterly by the Safe
     Medication Practices       hydromorPHONE, as compared to morphine and                 heparin. The most common factors associated with
  Committee of the University   confusion between the names hydromorPHONE                  these mix-ups are: mental slips since both drugs are
    of Washington Medical
            Center              and morphine. HydromorPHONE is five times                  dosed in units and similar packaging of insulin and
                                MORE POTENT than morphine. The UWMC                        heparin.
  Chair: Kim Donnelly, R.Ph.
  kimdon@u.washington.edu       recommend IV starting dose of hydromorPHONE
                                is 0.5-1mg.

                                                    Risk Management/Quality Improvement Work Product
                                                               Do Not Place In Medical Record
                                                    Confidential Pursuant to Rcw4.24.240-250 & 70.41.200

						
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