Opportunities for Research Collaboration Calibration and

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					    Opportunities for Research Collaboration

    Calibration and Standardization Seminar
               December 19, 2008

                  William Brantley (PhD)
Professor, Division of Restorative and Prosthetic Dentistry
 Director, Graduate Program in Dental Materials Science
Graduate Program in Dental Materials Science
Research-oriented with no clinical treatment of patients
MS Program is in Division of Restorative and Prosthetic
  Dentistry with PhD in Oral Biology (Biomaterials
Broad curriculum in modern dental materials science
Program objective is training of future dental materials
   science faculty and people who desire industry R & D
   careers in dental materials and other biomaterials
Four stipended positions have historically been available
  for qualified applicants ― all currently filled
Dentists and non-dentists (engineering and chemistry
  backgrounds) have been accepted into program
         Graduate Program Faculty
             Research Focus Areas

William Brantley (PhD) ― Alloys and general dental
   materials science
Isabelle Denry (DDS, PhD) ― New ceramics and
   characterization of ceramics
William Johnston (PhD) ― Color science and general
   dental materials science
Scott Schricker (PhD) ― Polymeric materials and
  tissue engineering
     Dental Materials Science Program
                MS Degree

Two-year duration if only MS degree desired
Combined with PhD program for PhD candidates
International PhD students first admitted to MS Program
Learn OSU academic style and writing in English
                  Curriculum for MS Program
Four Major Dent 700.08 Core Courses – Sequential in Alternate Years
Impression Materials, Gypsum Products and Investments (Johnston)
Alloys (Brantley)
Prosthetic Polymers and Related Materials (Schricker)
Ceramics (Denry)

Other Major Courses
Dent 800 Statistical Inferences and Applications to Dentistry (Rashid)
Dent 802 Introduction to Dental Research Designs (Johnston)
BME 631 Fundamentals of Biomaterials
Dent 999 Research (MS Thesis Project)

Additional Courses – Depend on advisor and research focus – Areas
recommended are materials science and engineering, chemistry,
BME, statistics, and other Dent 700.08 courses (amalgams, composite
resins, implant science, and mechanical behavior of dental materials)
  Oral Biology PhD Program (Biomaterials Track)

Dent 884 (Current Issues in Oral Biology) – variable topics, with
   different courses usually offered twice each year (Past examples:
   neuroscience, microbiology, immunology, biocompatibility of
   materials, wound healing, apoptosis, bone, and research
BME course areas: cell biology/biochemistry, cell/tissue engineering,
  biological aspects of materials, and nanoscience – selection
  depends on research focus and advisor (not mandatory)
Dent 700.08 courses (see MS Program) and statistics courses
Graduate seminar and ethics course
Laboratory rotations if needed to select advisor and research topic
   (not mandatory)
Some students may take courses in Department of Materials Science
   and Engineering (more quantitative and not mandatory)
Dent 999 – PhD research project (typically two years – overall time for
   degree is 4-5 years and little time lost if enroll first as MS student)
Research Collaboration
       Opportunities for Faculty Research

Several new graduate students have recently been admitted
   into the Dental Materials Science Program
All of these new students are providing their own support
New research projects will be needed for their MS theses
Projects can involve faculty collaboration within Division
   and across Divisions, and thesis committee membership
   or co-directorship if faculty member wants greater level
   of involvement (Need to have graduate faculty status)

Example of experimental collaboration across Divisions:
Brantley and Mendel – Darin Lunt in Orthodontics for impact
   testing of mouthguard materials
   Possible Projects and Division Laboratories
Effects of manipulation differences on properties of materials
    (e.g., working time, setting time, dimensional changes, fracture
    strength, fracture toughness, bond strength, and casting defects)
Laboratory measurements comparing products of same type from
   different manufacturers (e.g., composite resins, impression
   materials, cements, casting alloys, and implants) ― of particular
   clinical importance when new products of unknown performance
   are introduced by manufacturers
Restorative Research Laboratory is well-equipped ― specimen
   preparation areas, mechanical testing machines (Instron and
   MTS), optical microscope, measuring microscope, apparatus for
   contact angle measurement, microhardness tester, furnaces,
   casting area, and wear machine [Seghi] (SEM/EDS, x-ray
   diffraction, and TEM located in MSE – user fees required)
Polymer Research Laboratory (Schricker) has apparatus for FTIR and
   DSC analyses (functional groups and structural transformations)
Colorimeters and other apparatus for color science (Johnston)
Strategies for Developing Collaborative Projects

New graduate students initially observe current investigations
  and visit College dental laboratories

Program faculty meet with new graduate students about their
   research interests and arrange for collaboration meetings
   with interested College faculty [Please communicate your
   interest – clinicians have advantage of seeing needs]

Project development requires review of current published
   literature, planning of initial pilot experiments with power
   analysis, design of project with control and experimental
   groups, and decision about mode of statistical analysis

Substantial extramural funding is not needed since availability
   of laboratory equipment, personnel who do not require
   support, and contribution of materials by manufacturers
                   Key Links
PubMed ― http://www.ncbi.nlm.nih.gov/pubmed/
Search medical/dental/biomedical literature by
   author or by subject (Other search engines for
   engineering journals)

OSU Library ― http://library.osu.edu/
Go to “Quicklinks”: Online Journal List to access
  specific journals (Need to log in with username
  and password)

Recent articles in most journals of dental materials
  interest can be downloaded without going to
  Health Sciences Library

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