PETCT and SPECTCT To Plan and Monitor the Treatment

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PET/CT and SPECT/CT To Plan and Monitor the Treatment of Cancer

Description:    The Johns Hopkins University School of Medicine
                Course Directors: Henry N. Wagner, Jr., MD and Richard L. Wahl, MD

                The precise tailoring of treatment for patients with cancer is an unmet challenge. The goal is to only
                administer treatments that have a high probability of being effective. Imaging with PET/CT and
                SPECT/CT provides methods that will help achieve this goal. The program covers the current clinical
                challenges, the new emerging answers from imaging, and how these methods can be applied to
                patient care.

                Short descriptions of the fundamentals of maximizing the performance of these procedures are
                presented and a greater emphasis is put on interpretation of the studies. Johns Hopkins physicians
                and visiting experts describe how to use PET/CT and SPECT/CT to help solve the problems
                encountered when treating patients, and nuclear medicine physicians with extensive experience
                using these techniques give insight into how best to tailor the studies for patients with various
                types of cancer.

                Learning Objectives

                After viewing this program, participants should be able to:

                - Be familiar with the basic techniques used to perform a PET/CT or SPECT/CT study and the steps
                necessary to perform several studies on the same patient and obtain useful quantitative response
                data
                - Gain perspective about which patients benefit the most from these studies to assess response to
                treatment
                - Learn how Johns Hopkins physicians are using PET/CT and SPECT/CT studies to meet the
                challenges faced when treating patients
                - Understand how this field is rapidly developing and gain insight into the exciting areas that lie
                ahead

                Accreditation Statement

                The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for
                Continuing Medical Education to provide continuing medical education for physicians. The Johns
                Hopkins University School of Medicine takes responsibility for the content, quality, and scientific
                integrity of this CME activity.


                Credit Designation

                The Johns Hopkins University School of Medicine designates this educational activity for a
                maximum of 8.5 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit
                commensurate with the extent of their participation in the activity.
                Release date: November 28, 2006
                Credits expire: November 28, 2009

                CME credit is obtained upon successful completion of an activity evaluation. A processing fee must
                accompany the completed evaluation application.


                Faculty Disclosure

                It is the policy of The Johns Hopkins University School of Medicine that the faculty and provider
                disclose real or apparent conflicts of interest relating to the topics of this educational activity, and
                also disclose discussions of unlabeled/unapproved uses of drugs or devices during their
                presentation(s). The Johns Hopkins University School of Medicine OCME has established policies in
            place that will identify and resolve all conflicts of interest prior to this educational activity. Detailed
            disclosure will be made in the course handout materials.

            A note on the available formats:

            DVD: 8 DVDs packaged in a convenient carrying case, comprehensive program syllabus, program
            evaluation



Contents:   Topics & Speakers


            Recent Advances in Molecular Imaging
            Henry N. Wagner Jr., MD
            Overview of Current Approaches to Cure Cancer: Why We Succeed and Why We Fail
            William Matsui, MD

            Imaging Biomarkers in Response to Cancer Treatment
            Daniel C. Sullivan, MD

            STANDARDS OF ASSESSMENT OF TUMOR RESPONSE

            Anatomical Imaging: The WHO and RECIST Response Criteria
            Stephen J. Gwyther, FRCS, FRCR

            PET IMAGING: Emerging Criteria to Determine Response to Treatment
            Wolfgang A. Weber, MD

            TECHNICAL CONSIDERATIONS IN RESPONSE ASSESSMENT ILLUSTRATED WITH PATIENT STUDIES

            Obtaining Reliable Anatomical Data
            Stephen J. Gwyther, FRCS, FRCR

            Obtaining Reliable Quantitative PET/CT Data
            Wolfgang A. Weber, MD

            Obtaining Reliable Quantitative SPECT/CT Data
            Eric Frey, PhD

            Planning Radiation Treatment
            Perry W. Grigsby, MD

            INDIVIDUALIZING PATIENT TREATMENT

            Medical Therapies for Breast Cancer
            Antonio C. Wolff, MD, FACP

            Planning and Monitoring Treatment of Breast Cancer with PET/CT
            Richard L. Wahl, MD

            Clinical Challenges in Patients with Esophageal Cancer
            Michael K. Gibson, MD

            Planning and Monitoring Treatment of Esophageal Cancer with PET/CT
            Wolfgang A. Weber, MD

            Clinical Challenges in Treating Patients with Ovarian Cancer
            Robert E. Bristow, MD

            LYMPHOMA
            How Imaging Helps in the Individualization of Radio-immunotherapy Doses for I-131 and Y-90 Anti-
            CD-20 Therapy
            Richard L. Wahl, MD
PROBLEMS AND SOLUTIONS IN THERAPY ASSESSMENT

A Radiation Oncologist’s Use of PET in Patients with Cervical Cancer
Perry W. Grigsby, MD

Clinical Challenges in Treating Patients With Lung Cancer
Rosalyn Juergens, MD

Measuring Response to Treatment in Patients with Lung Cancer
Hubert J. Vesselle, MD, PhD

ADVANCES ON THE HORIZON

Imaging Tumor Hypoxia
Farrokh Dehdashti, MD

Imaging Tumor Proliferation
Hubert J. Vesselle, MD, PhD

Imaging Hormone Receptors
Farrokh Dehdashti, MD

Course Directors

Henry N. Wagner, Jr., MD
Professor Emeritus of Medicine and Radiology; Professor of Environmental Health Sciences;
Director, Division of Radiation Health Sciences, Johns Hopkins Bloomberg School of Public Health

Richard L. Wahl, MD
Professor of Radiology and Oncology; Henry N. Wagner, Jr., M.D. Professor of Nuclear Medicine;
Director, Division of Nuclear Medicine/PET, The Johns Hopkins School of Medicine

Johns Hopkins Faculty

Robert E. Bristow, MD
Associate Professor and Director, The Kelly Gynecologic Oncology Service Department of
Gynecology and Obstetrics

Eric Frey, PhD
Associate Professor of Radiology and Environmental Health Science, Bloomberg School of Public
Health

Michael K. Gibson, MD
Assistant Professor of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns
Hopkins

Rosalyn Juergens, MD
Thoracic Clinical Oncology Fellow

William Matsui, MD
Assistant Professor of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns
Hopkins

Antonio C. Wolff, MD, FACP
Associate Professor of Oncology, Breast Cancer Program The Sidney Kimmel Comprehensive Cancer
Center at Johns Hopkins

Visiting Faculty

Farrokh Dehdashti, MD
Professor of Radiology, Mallinckrodt Institute of Radiology, St. Louis, Missouri
            Perry W. Grigsby, MD
            Professor of Radiation Oncology/Nuclear Medicine and Gynecologic Oncology, Mallinckrodt Institute
            of Radiology, St. Louis, Missouri

            Stephen J. Gwyther, FRCS, FRCR
            Department of Medical Imaging, East Surrey Hospital, Redhill, Surrey, United Kingdom

            Daniel C. Sullivan, MD
            Associate Director, National Cancer Institute, Cancer Imaging Program, Bethesda, Maryland

            Hubert J. Vesselle, MD, PhD
            Associate Professor of Radiology, University of Washington, Seattle, Washington

            Wolfgang A. Weber, MD
            Associate Professor of Molecular and Medical Pharmacology, University of California Los Angeles,
            Los Angeles, California



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