ARPATP Report of Awards - 2002

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Advanced Research Program B 2001 Advanced Technology Program B 2001 Report of Awards May 2002 Texas Higher Education Coordinating Board Division of Finance, Campus Planning and Research P.O. Box 12788 Austin, Texas 78711 Texas Higher Education Coordinating Board Pamela P. Willeford (Chairman) Martin Basaldua, M.D. (Vice Chair) Neal Adams Ricardo G. Cigarroa Jr., M.D. Kevin P. Eltife Jerry Farrington Raul B. Fernandez Cathy Obriotti Green Gerry Griffin Carey Hobbs Adair Margo Lorraine Perryman Hector de J. Ruiz Robert W. Shepard Windy Sitton Terderma L. Ussery, II Austin Houston Bedford Corpus Christi Tyler Dallas San Antonio San Antonio Hunt Waco El Paso Odessa Austin Harlingen Lubbock Dallas COORDINATING BOARD MISSION The mission of the Texas Higher Education Coordinating Board is to provide the Legislature advice and comprehensive planning capability for higher education, to coordinate the effective delivery of higher education, to administer programs efficiently and to improve higher education for the people of Texas. COORDINATING BOARD PHILOSOPHY The Texas Higher Education Coordinating Board will promote access to quality higher education across the state with the conviction that access without quality is mediocrity and that quality without access is unacceptable. The Board will be open, ethical, responsive, and committed to public service. The Board will approach its work with a sense of purpose and responsibility to the people of Texas and is committed to the best use of public monies. Created by the Texas Legislature in 1965, the Texas Higher Education Coordinating Board works with institutions of higher education, other state agencies, the Legislature and the Governor to ensure that Texans seeking higher education have access to high quality programs. The Board's overall responsibilities include assessing the state of higher education in Texas, making recommendations to the Governor, Legislature and institutions for its enhancement, and establishing policies for the efficient and effective use of the state's higher education resources. Table of Contents Introduction .................................................................................................................................... 1 Role of the Advisory Committee on Research Programs .............................................................. 2 Solicitation of Research Proposals ................................................................................................ 3 The Peer Review Process ............................................................................................................. 4 Summary of the 2001 Advanced Research and Advanced Technology Program Awards ......... 6 Texas - Mexico Border Region ....................................................................................................... 6 Biennial Evaluations of the Advanced Research and Advanced Technology Programs ............................................................................................................... 7 Acknowledgments .......................................................................................................................... 7 Appendices Appendix A: Appendix B: Appendix C: Appendix D: Appendix E: Appendix F: Affiliations of Review Panelists ...................................................................... Proposals Submitted by Research Area ....................................................... List of Funded Proposals ................................................................................ Funding by Institution ...................................................................................... Comparison of Awards in 1997, 1999 and 2001 ............................................ Pre-Proposal and Proposal Evaluation Forms ............................................... A-1 B-1 C-1 D-1 E-1 F-1 List of Tables Table 1: Advisory Committee on Research Programs, 2001 ................................................. 2 Table 2: Preliminary Allocations .............................................................................................. 3 Table 3: 2001 Review Panel Chairs ........................................................................................ 5 i Advanced Research Program/Advanced Technology Program Report of Awards Introduction In 1987, the 70th Texas Legislature created the Advanced Research Program (ARP) and the Advanced Technology Program (ATP) as complementary, statewide research programs providing peerreviewed, competitive grants to Texas college and university researchers. For the 1987-1988 biennium, $60 million was appropriated. Since then, approximately the same amount has been appropriated for the programs for each of the seven subsequent biennia. The Advanced Research Program is devoted to basic research designed to attract and retain the best students and researchers and help provide the knowledge base needed for innovation. Researchers at all public institutions of higher education are eligible to compete. The Advanced Technology Program is devoted to research with a technological objective and a long-term economic goal, but retains a strong educational component. It is designed to promote the state's economic growth and diversification by increasing the number and quality of scientists and engineers in Texas, enlarging the technology base available to business and industry, creating new products and services, and attracting new industries to Texas. Researchers at all Texas public and independent institutions of higher education are eligible to compete. In 2001, three types of proposals were considered:  Advanced Research Program proposals to support basic research in nine areas specified in statute.  Advanced Technology Program proposals to support applied research in 11 areas specified in statute and one newly created transportation research area.  ATP Technology Development and Transfer proposals to continue the development and transfer to the private sector of technology created under previous Advanced Research Program or Advanced Technology Program grants. A separate competition was held for each type of award. Proposals were invited based on peer review of shorter pre-proposals. The implementation strategy for the ARP/ATP features three key elements:  Policy guidelines and oversight are provided by the distinguished Texas scientists and engineers who are members of the Coordinating Board's Advisory Committee on Research Programs (ACORP);  Proposals are solicited in 21 different research areas from faculty members at institutions of higher education in the state; and  Proposals are peer reviewed by nationally prominent scientific and technological professionals, including industry and government representatives from Texas and throughout the nation and academic scientists from outside Texas. None of the reviewers are associated with or employed 1 by Texas higher education institutions. 2 This report outlines the procedures followed during the 2001 ARP/ATP proposal solicitation and review process and describes the outcomes of the competitions. Role of the Advisory Committee on Research Programs The Coordinating Board's Advisory Committee on Research Programs (ACORP) provides direction and guidance to the programs and ensures their quality. Chaired by Dr. Norman Hackerman, it is composed of 12 eminent Texas scientists and engineers from academe and industry representing a wide range of disciplines (see Table 1). Currently, five members of the National Academy of Science, the National Academy of Engineering, or the Institute of Medicine serve on the Committee. The Committee consistently recommends that the Coordinating Board seek proposals from all possible sources within the Texas higher education system and select the very best of these through a fair and open process. ACORP reviews the program announcement, makes a preliminary allocation of funds among disciplines, and reviews the recommendations of the review panels. Table 1 Advisory Committee on Research Programs, 2001 (Membership list through December 31, 2001) Norman Hackerman (Chair) .................................................................. President Emeritus, Rice University Keith W. Brown ............................................................ Vice President and General Manager, GeneScreen Orchid Biosciences, Inc., Dallas Rinn Cleavelin ....................................................................................... Chief Operating Officer, SEMATECH R. Gary Daniels ....................................... Senior Vice President and General Manager (retired), Motorola Bonnie J. Dunbar ..................................................................... Assistant Director, University Research and Astronaut, NASA Johnson Space Center Frank Gerome ........................................ Partner, STARTech Business Development Center, Richardson James L. Kinsey ........................... D.R. Bullard-Welch Foundation Professor of Science, Rice University Way Kuo ...................................................Wisenbaker Chair in Innovation and Associate Vice Chancellor of Engineering, Texas A&M University John McKetta .................................................... Professor Emeritus and Joe C. Walter, Jr. Chair Emeritus The University of Texas at Austin Bettie Sue Masters ..................................................................... Welch Foundation Professor of Chemistry The University of Texas Health Science Center at San Antonio Billy E. Welch .......................................................... Director (retired), Armstrong Laboratory, San Antonio Jane L. Winer ................................................. Dean, College of Arts and Sciences, Texas Tech University ACORP recommended that reviewers place special emphasis on research projects that address environmental and water resource issues of the Texas-Mexico border region, reflecting similar legislative interest in this area. 3 Solicitation of Research Proposals ACORP recommended the announcement of proposal solicitation and evaluation in March 2001. The committee reviewed the proposal submission process, recruitment of reviewers, and the peer review process. ACORP made preliminary budget allocations for the targeted research areas (see Table 2). Exact allocations were to be based upon the quality of proposals within each area. In February 2001, the Coordinating Board staff conducted a workshop for 35 Sponsored Programs officers to demonstrate a new electronic submission system for pre-proposals and proposals. The Sponsored Programs officers’ response was favorable overall, and their comments and suggestions were invaluable in helping improve development of the electronic system. With this system, investigators would create and track the progress of their submissions through the Coordinating Board’s web site. The Coordinating Board adopted the program announcement proposed by ACORP at its April 2001 meeting. After adoption, the program announcement was available on the Coordinating Board’s web site. Table 2 Preliminary Allocations Advanced Research Program Biological Sciences Chemistry Computer Sciences Earth Sciences Engineering Materials Science Mathematics Physics Social and Behavioral Sciences Advanced Technology Program Aerospace Agriculture/Aquaculture/Agricultural Biotechnology Biomedicine Computer and Information Engineering Energy Environmental Science and Engineering, Recycling, and Water Resources Manufacturing Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation $ 7,000,000 2,200,000 1,800,000 800,000 3,900,000 1,400,000 900,000 1,300,000 600,000 1,600,000 3,800,000 6,900,000 3,500,000 3,100,000 4,200,000 3,400,000 3,800,000 4,000,000 2,500,000 2,400,000 600,000 4 In Spring 2001, Coordinating Board staff conducted a series of briefings at nine campuses throughout the state, as well as televised briefings transmitted to 26 additional campuses. In addition, over 4,000 copies of the program announcement and 57 copies of a videotaped briefing were distributed to Texas institutions of higher education. In 2001, a pre-proposal review procedure was used to improve the quality of review and reduce the number of full proposals evaluated by all review panels in the Advanced Research and Advanced Technology Programs. In 2001, the Advisory Committee on Research Programs recommended an experimental electronic submission system for full proposals submitted to the Aerospace, Computer and Information Engineering, Computer Science, Engineering, Microelectronics, Telecommunications and Transportation research areas. By June 8, the Board received 3,100 pre-proposals that were filed electronically on the www.arpatp.com web site. Each pre-proposal specified a research area, project title, keywords, estimated budget, and brief discussion of the project’s goals and processes, staff, facilities and resources available, and student education and training opportunities. The pre-proposals were reviewed electronically and 1,409 were selected for full proposals. By the August 14 deadline, investigators at 50 institutions had submitted 1,344 full proposals. Of these, 318 were submitted and reviewed electronically. The electronic submission system for pre-proposals and proposals and the panel review process proved to be capable of operating under adverse conditions that included an internet virus known as the Nimda worm and after effects associated with the September 11 terrorist attacks in New York and Washington, D.C. The electronic system allowed for rapid transfer, handling, and access to electronically submitted pre-proposals, proposals, and reviews. The Peer Review Process To review proposals, 136 experts were organized into 16 panels. The chairs (see Table 3) and panelists were recruited from academe, national laboratories, and U.S. and Texas companies. No panelists were associated with any Texas university. The majority were from outside Texas and had not served previously. A list of reviewer affiliations is provided in Appendix A. The review criteria for the ARP proposals included the merit and soundness of the proposal, capability of the investigator(s) to perform the necessary research, adequacy of institutional commitment and resources, and potential positive effect on the infrastructure of science and engineering. In addition to those criteria, the ATP proposals were also evaluated on their prospects for commercialization, leveraging of grant funds to attract external funds, technology transfer, and meaningful industrial collaboration. Criteria for evaluating ATP Technology Development and Transfer proposals were the technical merit and soundness of the proposal, personnel, and physical resources available to the project, and the technology transfer plan. The proposal evaluation forms in Appendix F outline the evaluation criteria in more detail. 5 The Texas Legislature mandates that no more than 70 percent of the funds may be awarded to institutions in The University of Texas System and the Texas A&M System. Adjustments were made by Coordinating Board staff using priorities established by the panels to ensure that limit. To satisfy the 70 percent mandate, the five next-highest ranked proposals from non-UT/A&M system institutions were added to the 361 proposals initially selected by the review panels. Final allocations for the 366 proposals selected for funding were reviewed by ACORP. Table 3 2001 Review Panel Chairs Lynda Delph ...............................................................Associate Professor of Biology, Indiana University Hugh Ellis ..................Professor and Chair, Department of Geography and Environmental Engineering Johns Hopkins University Charles Emerson .......................... Joseph Leidy Professor and Chair, Cell and Developmental Biology University of Pennsylvania Medical Center M. Charles Gilbert ............................................................ Professor of Petrology, University of Oklahoma Warren Grobman .......................... Director, Interconnect and Lithography Software Systems, Motorola Vasken Hagopian ...................... Distinguished Research Professor of Physics, Florida State University David Hardt .................................................. Professor, Co-Director, Leaders for Manufacturing Program Massachusetts Institute of Technology John Hauser ................................................................ Professor of Electrical and Computer Engineering North Carolina State University Alan Karr .............................................. Professor and Director, National Institute of Statistical Sciences Research Triangle Park Neil Kestner ................................................................ Professor of Chemistry, Louisiana State University Michael McNaughton ........................................ Vice President for Chemistry and Chemical Engineering Southwest Research Institute Martin Massengale................................. Director, Center for Grassland Studies, University of Nebraska Robert Morff ...................................... Director of Medical Technology, Sentron Medical, Inc., Cincinnati Felicia Nowak ........................................................................ Associate Professor of Biomedical Sciences Ohio University Stanley Reynolds ....................... Professor and Head, Department of Economics, University of Arizona Michael Richard .......................................... Staff Research Chemist, Shell Chemical Company, Houston 6 In October 2001, the Advisory Committee on Research Programs recommended, based on the results of the peer review process, specific projects to the Coordinating Board for funding. The Board approved that recommendation and authorized the Commissioner to make additional awards if additional funds become available. The Advisory Committee on Research Programs recommended one additional award In January 2002 and five additional awards in April 2002 from funds returned by institutions. One institution declined to accept one of the original awards because it had accepted external funding from another source for the project. The awards were approved by the Commissioner of Higher Education. Summary of the 2001 Advanced Research and Advanced Technology Program Awards The $58,873,654 appropriated for these research grant programs, plus an additional $3,185,697 carried forward from the previous ARP/ATP awards, was distributed as recommended by the review panel chairs. A total of 371 proposals received funding B 144 Advanced Research Program proposals, 189 Advanced Technology Program proposals, and 38 Advanced Technology Program Development and Transfer proposals. The average award was $152,480. Two or more higher education institutions collaborated on 33 projects, and 14 of the collaborations included a public institution reporting less than $11 million in total research and development expenditures for Fiscal Year 2000. A list of the specific projects, principal investigators, institutions, and amounts awarded appears in Appendix C. Texas-Mexico Border Region The 76th Texas Legislature expressed interest in providing funding for projects that address environmental issues on the Texas-Mexico border. Review panels were directed to place special emphasis on those projects. The Environmental Science and Engineering review panel dedicated more than $760,000, or more than 18 percent of the total environmental sciences funding allocation, to four highly ranked border projects. Border Projects Awarded in 2001 Grant ARP/ATP Competitions: Hydrology and Salinity Monitoring and Modeling Along the Middle Rio Grande $212,500 Texas Agricultural Experiment Station Ranjan Muttiah; Seiiche Miyamoto Removal of Trihalomethanes from Drinking Water by Cometabolism in Nitrifying Biofilters $199,935 The University of Texas at Austin Gerald Speitel Pretreatment for Reverse Osmosis Membranes: Silica Removal to Increase Yield in Border Region $139,650 The University of Texas at Austin Desmond Lawler Extension of HF Radar for Water Currents and Direct Observation of Transport Model Coefficients $123,653 Texas A&M University – Corpus Christ James Bonner $85,000 The University of Texas at El Paso Rosa Fitzgerald Two awards were made in Social and Behavioral Sciences for projects involving topics related to the Texas/Mexico border region: Mujeres Sanas [Healthy Women]: Virtual Bridges for the 21st Century $100,000 University of North Texas Ruthann Masaracchia 7 Colonial and Community History: The Rehabilitation of an Historic Spanish Mission in Socorro, Texas $47,988 The University of Texas at Dallas Howard Campbell Biennial Evaluations of the Advanced Research and Advanced Technology Programs The legislation creating the Advanced Research and Advanced Technology Programs specifies that the Coordinating Board appoint a committee consisting of representatives of higher education and private research organizations to evaluate the programs= effectiveness every two years. The programs were last evaluated in fall 2000 by a committee appointed by Coordinating Board Chair Pamela Willeford. The committee reviewed documentation associated with the programs and met with representatives of the Governor=s Office, the Legislative Budget Board, the Senate Finance Committee, the House Appropriations Committee, project investigators, institutional administrators, reviewers, Industry representatives, and representatives of the Advisory Committee on Research Programs (ACORP). Dr. Edward A. Knapp, chair of the evaluation team and immediate past president and a professor at Santa Fe Institute, reported the evaluation committee=s findings to the Coordinating Board at its January 2001 meeting. The evaluation committee considered ARP and ATP to be outstanding, well-administered programs with an incredibly small staff and extremely low administrative costs. The panel strongly recommended that activities related to generating and developing quantitative measures of success be continued and expanded. The panel made four operational recommendations that included modifying budgetary procedures to be in line with federal programs, investigating the possibility of longer duration grants, encouraging multi-disciplinary programs and mechanisms, and disseminating information on the programs to senior management of private companies. Policy recommendations include restoring the appropriation for the programs to their original purchasing power, investigating the possibility of establishing a smaller program targeting emerging institutions, providing bridge funding to allow for completion of a project or technology transfer, and investigating the possibility of establishing mechanisms to allow discipline allocations to fit the needs of the evolving technical base in Texas. According to the committee, this is a very successful, mature, well-administered program which is bringing excellent return to the State, and inflation should not be allowed to diminish its effectiveness. Acknowledgments The Advisory Committee on Research Programs and its chair, Dr. Norman Hackerman, continue to make important and vital contributions to the success of these efforts. In addition, scientists and engineers at Texas higher education institutions ensure the quality of the program through the submission of more excellent proposals than can be funded. 8 Appendix A Affiliations of Review Panelists Texas Industry AgriPro Seed, Inc. Amarillo Biosciences Avant! Corporation British Petroleum EQE International GeneScreen, Inc. (2) Huntsman Corporation Karta Technologies Lockheed Martin Mediaprise Motorola, Inc. (4) Shell Chemical Company Southwest Research Institute Texas Cattle Feeders Association Texas Instruments (2) WorldCom, Inc. U.S. Industry GlaxoSmithKline Pharmaceuticals (2) IGC-Super Power, LLC IBM T.J. Watson Research Company Microsoft Research National Institute of Statistical Sciences Phillips Medical System, Washington University School of Medicine Sentron Medical, Inc. Sugen Government Affiliation California Coastal Commission Kansas Geological Survey Lawrence Berkeley National Laboratory Lawrence Livermore National Laboratory (3) NASA National Institutes of Environmental Health Sciences Sandia National Labs University of California Energy Institute USDA, ARS, KHD National Aquaculture Research Center USDA-National Resources Conservation Service USDA-Southern Regional Research Center U.S. Department of Energy Institutions Auburn University California State University – Northridge Carnegie Mellon University Case Western Reserve University, School of Medicine Clemson University Colorado State University Cornell University (3) Duke University Duke University Medical Center Emory University Florida State University Gettysburg College Indiana University-Bloomington (2) Iowa State University Johns Hopkins Medical School Johns Hopkins University Kenyon University Louisiana State University (3) Michigan State University Michigan Technological University Minnesota Institute of Technology Mississippi State University North Carolina State University (2) Northeastern University Ohio University Oklahoma State University-Stillwater (2) Oklahoma State University-Tulsa Penn State University Purdue University San Diego State University (2) State University of New York at Buffalo (2) The Salk Institute for Biological Studies Tufts University Sackler School of Biomedicine University of Arizona (2) University of Arkansas University of California – Berkeley University of California at Irvine University of California at San Diego (2) University of Colorado University of Florida University of Illinois University of Iowa University of Louisville (3) University of Massachusetts University of Miami School of Medicine (2) University of Michigan A-1 University of Missouri – Rolla (3) University of Nebraska – Lincoln (3) University of Oklahoma (4) University of Pennsylvania Medical Center University of Pittsburgh School of Medicine University of South Florida University of Utah University of Virginia Health Sciences Center University of Washington University of Wisconsin-Madison University of Wyoming Vanderbilt University (2) Virginia Commonwealth University Virginia Institute of Technology Washington University in St. Louis, School of Medicine A-2 Appendix B Proposals Submitted by Research Area Number Advanced Research Program Biological Sciences - All Other Biological Sciences - Molecular Biology and Genetics Chemistry Computer Science Earth Sciences Engineering - All Other Engineering - Electrical and Electronics Materials Science Mathematics Physics and Astronomy Social and Behavioral Sciences Advanced Technology Program Aerospace Agriculture/Aquaculture/Agricultural Biotechnology Biomedicine Computer and Information Engineering Energy Environmental Science and Engineering Manufacturing Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation ATP Development and Transfer Aerospace Agriculture/Aquaculture/Agricultural Biotechnology Biomedicine Computer and Information Engineering Energy Environmental Science and Engineering Manufacturing Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation Dollars Requested 22,232,885 30,927,456 9,504,195 6,863,241 4,320,357 13,734,964 5,644,485 6,471,089 2,900,748 6,733,311 4,325,839 $113,658,570 4,611,918 10,305,125 21,919,723 8,618,590 10,007,801 10,797,556 6,413,081 11,564,951 12,014,275 4,958,826 4,248,551 1,202,285 $106,662,682 640,000 984,533 3,131,983 917,774 1,247,801 1,706,322 764,133 1,193,594 2,469,530 1,210,225 1,394,461 298,880 $15,959,235 $122,621,917 $236,280,487 Submitted 120 Submitted 162 54 43 34 89 33 38 41 48 44 706 24 57 105 49 56 60 34 56 59 26 24 9 559 3 6 14 6 7 9 5 5 12 5 6 1 79 638 1,344 ATP Totals GRAND TOTALS B-1 Appendix C List of Funded Proposals Advanced Research Program Biological Sciences – All Other ..........................................................................................................C-2 Biological Sciences – Molecular Biology and Genetics .....................................................................C-2 Chemistry ...........................................................................................................................................C-3 Computer Sciences ............................................................................................................................C-4 Earth Sciences ...................................................................................................................................C-4 Engineering – All Other ......................................................................................................................C-5 Engineering – Electrical and Electronics ...........................................................................................C-5 Materials Science ............................................................................................................................... C-6 Mathematics .......................................................................................................................................C-6 Physics and Astronomy......................................................................................................................C-7 Social and Behavioral Sciences ........................................................................................................C-7 Advanced Technology Program Aerospace ..........................................................................................................................................C-8 Agriculture/Aquaculture/Agricultural Biotechnology ..........................................................................C-8 Biomedicine ........................................................................................................................................C-9 Computer and Information Engineering...........................................................................................C-10 Energy ..............................................................................................................................................C-10 Environmental Science and Engineering, Recycling and Water Resources ..................................C-11 Manufacturing Technology ..............................................................................................................C-12 Materials Technology .......................................................................................................................C-12 Medical Biotechnology .....................................................................................................................C-13 Microelectronics ...............................................................................................................................C-13 Telecommunications ........................................................................................................................C-14 Transportation ..................................................................................................................................C-14 Advanced Technology Development and Transfer Aerospace ........................................................................................................................................C-15 Agriculture/Aquaculture/Agricultural Biotechnology ........................................................................C-15 Biomedicine ......................................................................................................................................C-15 Computer and Information Engineering ...........................................................................................C-15 Energy ..............................................................................................................................................C-16 Environmental Science and Engineering, Recycling and Water Resources ..................................C-16 Manufacturing Technology ..............................................................................................................C-16 Materials Technology .......................................................................................................................C-16 Medical Biotechnology .....................................................................................................................C-17 Microelectronics ...............................................................................................................................C-17 Telecommunications ........................................................................................................................C-17 Transportation ..................................................................................................................................C-17 C-1 Advanced Research Program 2001 Funded Projects Biological Sciences - All Other Landscape Epidemiology of a Texas Hantavirus: Habitat Structure and Potential Role of Parasites $249,520 Texas Tech University Marilyn Houck; Nancy McIntyre Genetic Diversity and Disease Transmission $200,000 University of Houston Diane Wiernasz; Blaine Cole Natural Killer Cell uPA and uPAR in Matrix Degradation and Tumor Infiltration $200,000 UNT Health Science Center at Fort Worth Richard Kitson; Ronald Goldfarb Opioids, Nitric Oxide, and Vagal Control of Heart Rhythm $199,600 UNT Health Science Center at Fort Worth James Caffrey Function and Regulation of Polycystin-2 in C. elegans – A Model for Polycystic Kidney Disease $192,000 UNT Health Science Center at Fort Worth Peter Koulen Artificial Stable RNA Sequestration of Heavy Metals $176,076 University of Houston George Fox Cell-Specific Induction of GRK Subtypes Mediates Opioid Receptor Cross Talk Mechanisms $173,260 University of Houston Kelly Standifer Expression and Function of the Steroidogenic Acute Regulatory (StAR) Protein in Mammalian Brain $167,493 TTU Health Sciences Center Peter Syapin; Douglas Stocco Ultraviolet Communication in Swordtails $152,299 The University of Texas at Austin Michael Ryan Microarray-Based Neuropathology Studies $100,355 The University of Texas at Austin John T. McDevitt $51,255 Southwest Texas State University Joseph Koke Calcium Channel Dysfunction in a Transgenic Model of Heart Failure $149,860 UNT Health Science Center at Fort Worth Glenn Dillon; Stephen Grant Mechanisms of Cardiovascular Disease: Ion Channel Modulation by Angiotensin II $146,588 UT Health Science Center at San Antonio Glenn Toney Biochemical and Structural Studies of Human CIF150, a Subunit of TFIID $145,500 UT M.D. Anderson Cancer Center Raymond Jacobson Influence of Adipose Differentiation Related Protein on Intracellular Lipid Trafficking $144,000 Texas Agricultural Experiment Station Barbara Atshaves; Ann Kier Mechanisms of Manganese-Induced Glial Injury in Parkinson's Using a Novel Real-Time Screening Assay $144,000 Texas Agricultural Experiment Station Ron Tjalkens; Roula Mouneimne Adaptation of a Multi-Photon Microscope to Quantify Intracellular Diffusion $141,806 UT Health Science Center at Houston Neal Waxham Systematics and Phylogeography of the Model Cricket, Allonemobius $138,624 The University of Texas at Arlington Jeremy Marshall Rapid Screening Method Using Aptamer-Liposomes for Customized Cancer Treatment $132,828 UT Health Science Center at San Antonio Beth Goins; Mohan Natarajan Water Quality Issues: Real-time Assessment of Nutrients in Aquatic Systems $100,368 The University of Texas at Arlington Thomas Chrzanowski Anti-Edema Mechanisms: Nitric Oxide and Thromboxane in the Regulation of Lymphatic Function $95,674 Texas Agricultural Experiment Station Randolph Stewart; Glen Laine Biological Sciences - Molecular Biology and Genetics Comparative Genomics to Identify Disease Traits in the Horse $173,376 Texas A&M University Bhanu Chowdhary $66,624 Texas Agricultural Experiment Station Loren C. Skow Genetics of Maternal/Fetal Xenobiotic Metabolism and Childhood Cancer Risk $236,553 UT Southwestern Medical Center at Dallas Gail Tomlinson Interaction of the Menin Tumor Suppressor Protein with JunD $200,000 TTU Health Sciences Center Curt Pfarr Microarray Based Global Mapping of DNA-Protein Interactions at Promoters in Human Cells $200,000 The University of Texas at Austin Vishwanath Iyer C-2 Novel Approach for Gene Therapy of Breast Cancer $192,000 The University of Texas at Austin Jaquelin Dudley; Shelley Payne Nuclear Factor-kappaB Inactivation of Progesterone Receptor Function in the Initiation of Labor $192,000 UT Southwestern Medical Center at Dallas Carole Mendelson Free Radical-Promoted NFkB/bcl-2 Interaction Affects Gene Expression in the Aged Brain $190,883 UT Medical Branch at Galveston Giulio Taglialatela; Steven Widen Study the Role of MEKK3 in Cardiovascular Development by Conditional MEKK3-Knockout/Transgenic Mice $186,200 UT M.D. Anderson Cancer Center Bing Su Molecular Basis of Neuroinvasiveness and Mosquito Competence of West Nile Virus $180,000 UT Medical Branch at Galveston Alan Barrett Genetic Microarrays for the Discovery of New Lyme Disease Vaccines $175,104 UT Southwestern Medical Center at Dallas Michael Norgard The Role of Notch, Its Ligands, and Fringe in Cell Adhesion and Epithelia Maintenance $168,471 Texas Agricultural Experiment Station Vladislav Panin Identification of Vertebrate Learning and Memory Genes $153,600 University of Houston Gregory Cahill Function of Ashwin in Early Vertebrate Development $100,000 University of Houston Amy Sater $50,000 University of Houston - Downtown Akif Uzman Proton Pumps at Cell's Surface Are Targets to Halt Angiogenesis and Metastasis in Breast Cancer Cell $150,000 TTU Health Sciences Center Raul Martinez-Zaguilan High-Throughput Structure Determination of Proteins by Combining Bioinformatics and NMR $147,000 Texas Agricultural Experiment Station Andy LiWang; Jerry Tsai Host-Plant Interference in Sinorhizobium meliloti Quorum Sensing $147,000 The University of Texas at Dallas Juan Gonzalez Reconstructing Gene Networks by Mining Expression, Genomic and Literature Data $147,000 The University of Texas at Austin Edward Marcotte; Inderjit Dhillon GTP Signalling in Bacteria $145,500 UT Health Science Center at San Antonio William Haldenwang A New Mouse Model for Human Obesity $144,000 UT Southwestern Medical Center at Dallas Andrew Zinn Ribozyme Biosensors for Influenza Virus $144,000 The University of Texas at Austin Andrew Ellington; Robert Krug Characterization of a Novel Signaling Pathway Inhibiting Btk-Dependent Activation of B Lymphocytes $143,946 UT Southwestern Medical Center at Dallas Anne Satterthwaite Function of Flotillin 2 in Metastatic Melanoma $96,000 UT M.D. Anderson Cancer Center Madeleine Duvic; Parul Hazarika Function of HECT Ubiquitin Ligases in Saccharomyces Cerevisiae $96,000 The University of Texas at Austin Jon Huibregtse Chemistry Raman Near-Field Scanning Optical Microscopy $192,000 The University of Texas at Austin Alan Campion Nanostructuring of Metal Oxide Surfaces Induced by Radiation Enhanced Diffusion $188,480 University of Houston J. W. Rabalais 19 F Nuclear Magnetic Resonance Probes of RNA Structure and Dynamics $97,825 Texas A&M University Victoria DeRose $52,175 Texas Agricultural Experiment Station David Giedroc New Quantum States with Relative Minimum Uncertainty and Maximum Shape Control $150,000 University of Houston Donald Kouri; Emmanouil Papadakis Probing the Structural Basis for Enzyme Specificity $150,000 The University of Texas at Austin Stephen Martin The Creation of Chiral Phosphorus Synthons $150,000 Texas A&M University Frank Raushel New Adsorbates for Soft Lithographic Patterning $149,928 University of Houston T. Randall Lee Cu(I) Complexes as Low Cost Photoredox Catalysts $149,500 University of Houston Randolph Thummel C-3 Redox Properties of Electroactive Porphyrin-Based Components for 'Molecular Electronics' $147,000 University of Houston Karl Kadish Stereoselective Aldols of Masked 2,2-Dimethyl-1,3-dioxoalkanes: Synthesis of Peloruside A $147,000 The University of Texas at Austin Brian Pagenkopf Identification of Ornithine Decarboxylase Inhibitors for the Treatment of African Sleeping Sickness $144,000 UT Southwestern Medical Center at Dallas Margaret Phillips Synthesis of Peloruside A $131,424 UT Southwestern Medical Center at Dallas Jef De Brabander New Applications of Electrogenerated Chemiluminescence $108,561 The University of Texas at Austin Allen Bard Orthogonal Molecular Recognition Motifs for Use in Nanoscale Assembly: Synthetic DNA Surrogates $100,000 The University of Texas at Austin Michael Krische; Eric Anslyn Computational Chemistry for Biopolymer-Inorganic Materials Recognition $98,000 The University of Texas at Austin Peter Rossky Atmospheric Photochemical Oxidation of Isoprene Relevant to Urban and Regional Air Quality $94,766 Texas A&M University Simon North; Renyi Zhang Computer Science Congestion Controlled Streaming Media for the Internet $200,000 The University of Texas at Austin Simon Lam Flexible Integrated Caching Approach (FICA) for Efficient Content Delivery in Wireless Internet $131,222 The University of Texas at Arlington Sajal Das; Mohan Kumar $66,000 Midwestern State University Nelson Passos Answer Set Programming $195,706 The University of Texas at Austin Vladimir Lifschitz Federated Multicast in IP $111,061 The University of Texas at Austin Mohamed Gouda $84,257 Southwest Texas State University Wuxu Peng Synchronization Protocols for Wireless Multimedia Systems $98,400 University of North Texas Azzedine Boukerche $96,800 The University of Texas at Dallas Imrich Chlamtac Knowledge Mining for Open-Domain Information Extraction $189,030 The University of Texas at Austin Sanda Harabagiu Tree-Based Data Structures to Accelerate Lookup in Biological Sequence Databases $159,768 The University of Texas at Austin Daniel Miranker Scalable Low-Overhead Fault-Tolerance $147,000 The University of Texas at Austin Lorenzo Alvisi; Calvin Lin Coevolution of Neural Networks for Multi-Agent Tasks $146,936 The University of Texas at Austin Risto Miikkulainen Programming Distributed Systems with Randomized Shared Objects $144,000 Texas Engineering Experiment Station Jennifer Welch Algorithms on High-Level Synthesis and Optimization for High-Performance Systems $96,000 The University of Texas at Dallas Hsingmean Sha Earth Sciences Geophysical and Petrological View, Magmatic Contribution to Intracontinental Growth: Rio Grande Rift $112,350 The University of Texas at El Paso Kate C. Miller $37,650 Texas Tech University Calvin Barnes Sub-Salt Imaging with Typical Marine P Data: Application to Offshore Gulf of Mexico E&P $150,000 University of Houston Arthur Weglein 3-D Seismic Investigation of Gas Hydrates, a Potential New Energy Source $146,712 The University of Texas at Dallas George McMechan Geophysical Studies of the Deep Structure of the Continents: International Collaborations $99,790 The University of Texas at El Paso G. Randy Keller Geochemical Fate and Bioavailability of Arsenic in Pesticide-Applied Soils: Phase I: In-vitro Study $98,000 The University of Texas at San Antonio Dibyendu Sarkar Estimating Activities of H2O in the Earth's Mantle: A Comparison of Three Methods $95,050 Texas A&M University Will Lamb; Robert Popp C-4 Characterizing Fault Control of Groundwater Movement Using Geophysical Techniques $79,628 The University of Texas at El Paso Diane Doser Engineering - All Other Dynamic Models for Flapping Wing Micro-Air Vehicles Derived from Hummingbird Flight $241,336 The University of Texas at Austin Robert Dudley; Maruthi Akella Intelligent Vision Sensing for Motion Based Guidance $240,000 Texas Engineering Experiment Station John Valasek; John Junkins Linking Microstructure and Macroscopically Observed Properties of Suspensions and Composites $200,000 Texas Tech University Alan Graham; Lorne Davis High-Resolution Laser-Induced Photoacoustic Tomography of the Breast $192,000 Texas Engineering Experiment Station Lihong Wang; Hsin-i Wu Towards Early Cancer Detection: A Novel Functionally Integrated Cytoskeleton Model $192,000 The University of Texas at Austin Tess Moon Laser-Induced Ultrasound Thermometry for Silicon Wafer Annealing $191,856 Texas Engineering Experiment Station Steve Suh; Ravinder Chona Development of Advanced, Nanostructured Catalysts to Remove Pollutants from Exhaust Gases $185,710 Texas Engineering Experiment Station Jerald Caton Nanofabrication and Performance Evaluation of a New Class of Membrane Filters for Water Purification $175,600 University of Houston Shankar Chellam; Paul Ruchhoeft A New Generation Simulator for Improved Oil Recovery Processes $150,000 The University of Texas at Austin Mojdeh Delshad Physical Simulation of Extreme Winds from Thunderstorms $148,600 Texas Tech University Chris Letchford; Darryl James Establishing Loads for the Safe Design of Wind Turbines Using Simulations and Field Data $146,751 The University of Texas at Austin Lance Manuel Magnetic Shape Memory Alloy Actuators $145,500 Texas Engineering Experiment Station Dimitris Lagoudas; John Slattery New Models of Low-Level Visual Search and Applications to Robotic Vision, Detection, and Data Mining $143,950 The University of Texas at Austin Lawrence Cormack; Alan Bovik Development of Test Methodology for Systemic Exploration of Immature Fiber Content in Texas Cotton $142,496 Texas Tech University James Simonton; Mario Beruvides Mass Transport Studies for Mammalian Cell Cultures in Micro Gravity $94,810 University of Houston Stanley Kleis Engineering - Electrical and Electronics A High-Speed Signal-Processing Algorithm/Electronics for Transducers with Exponential-Decay Response $250,000 UT M.D. Anderson Cancer Center Wai-Hoi Wong; Hongdi Li Development of Nanostructured Photonic Devices with Nonlinear Organic Materials $196,000 The University of Texas at Arlington Theresa Maldonado; Robert Magnusson Self-Aligned Multi-Color Photodetectors Based on III-Nitrides for Advanced Flame/Fire Detection $175,000 University of Houston David Starikov; Maria Mironova Dielectric Resonator Antenna Applications in Wireless Communications $160,000 University of Houston Stuart Long; David Shattuck On-Chip High-K Metal-Insulator-Metal (MIM) Capacitors for GHz Analog and Mixed Signal Applications $150,000 The University of Texas at Austin Dim-Lee Kwong Parallel Interconnect Modeling Engine for Wireless Communication System-on-a-Chip Interconnects $150,000 University of Houston Ji Chen; Donald Wilton Minimization of Integrated Circuit Burn-In Testing via Outlier Identification $115,958 Texas Engineering Experiment Station Duncan Walker Novel Sensing Technique for Location and Inspection of Underground Utility Distribution Systems $96,288 Texas Engineering Experiment Station Cam Nguyen $16,452 Texas Transportation Institute Tom Scullion Materials Science Electronic Nanoparticle-Tissue Composites for Targeted Biomolecule Delivery $244,520 The University of Texas at Austin Christine Schmidt; Brian Korgel C-5 Biologically Engineered Evolution of Physical Properties of Semiconductor Quantum Dots $196,000 The University of Texas at Austin Angela Belcher; Brent Iverson Rare-Earth-Metal Clusters as Single-Molecule Magnets $191,995 Texas A&M University Timothy Hughbanks A Low Temperature Interfacial Force Microscope for Surface Spectroscopy $163,584 Texas A&M University Glenn Agnolet Fundamental Study of Surface Damage Phenomena in Polymers $146,804 Texas Engineering Experiment Station Hung-Jue Sue Guest-Host Interactions in Zeolite Adsorbents $146,572 Texas Engineering Experiment Station Daniel Shantz Direct Writing of Thick Films Magnetostrictive Actuators from Nanoparticles $129,408 The University of Texas at Austin Desiderio Kovar; Michael Becker Effects of Chemical Mechanical Planarization on Electrical Properties of Low-k Materials $118,923 Southwest Texas State University Heather Galloway; Wilhelmus Geerts Development and Characterization of New, High Performance Polymers. $93,474 Texas Engineering Experiment Station Roger Morgan Mathematics Robustness of Mathematical and Statistical Models for the Analysis of Gene Expression Data $167,731 UT M.D. Anderson Cancer Center Kevin Coombes; Keith Baggerly Linking Modern Statistical Analysis to Lipoprotein Fingerprinting $120,960 Texas A&M University Tailen Hsing; Ronald Macfarlane Quantized Banach Spaces and Nonlinear Banach Space Theory $84,480 Texas A&M University William Johnson; Gilles Pisier Symmetry in Coupled Cell Systems and Neuroscience $82,500 University of Houston Martin Golubitsky 3-Dimensional Topology and Geometry $73,410 The University of Texas at Austin Cameron Gordon; Alan Reid Mathematical Analysis of Flutter Control Problem in Aircraft Wings $59,354 Texas Tech University Marianna Shubov Mathematical Modeling of Schistosomiasis $57,120 Texas Tech University Dean Victory; Edward Allen Quasilinear Hyperbolic Equations with Discontinuous Coefficients Arising in Blood Flow Modeling $50,000 University of Houston Suncica Canic Optimally Dense Packings of Spheres and Polyhedra $49,000 The University of Texas at Austin Charles Radin Overcoming Mathematical Difficulties in Two-Phase Flows $48,000 University of Houston Barbara Keyfitz Design and Analysis of Mathematical Models for Deformable Porous Media $47,305 The University of Texas at Austin R. E. Showalter Advanced Methodologies for Longitudinal/Clustered Data with Applications to Nutrition and Cancer $47,000 Texas A&M University Naisyin Wang; Raymond Carroll $0 Texas Agricultural Experiment Station Robert Chapkin Stability and Robustness in Biorhythms $45,000 Texas Tech University Clyde Martin Physics and Astronomy Spin Injection and Charge Pumping in Metallic Single-Wall Carbon Nanotubes $188,160 The University of Texas at Austin Zhen Yao; Qian Niu Dual-Readout Calorimetry for High-Quality Energy Measurements $150,000 Texas Tech University Richard Wigmans Multiple Raman Scattering in Solids for the New Coherent Sources of Ultrashort Pulses $150,000 Texas A&M University Olga Kocharovskaya; Alexei Sokolov Continuum Equations for Granular Media: Validation by Experiment and Molecular Dynamics Simulation $125,760 The University of Texas at Austin Jack Swift; Harry Swinney The Spin Hall Effect - Realizing a Pure Spin Current $125,000 Texas A&M University Winfried Teizer C-6 Determining the Radial Dependence of Particle Intensities from Coronal Mass Ejections $104,000 University of Houston Lawrence Pinsky Solid Xenon Particle Detector $98,000 Texas A&M University James White The Dynamical Structure of Nearby Galaxies: Mining Their Evolutionary History $96,000 The University of Texas at Austin Karl Gebhardt Search for New Physics with a New Proton Detector $95,760 The University of Texas at Arlington Andrew Brandt Dying Stars, Living Planets $90,160 The University of Texas at Austin Don Winget Galaxy Evolution Templates $83,928 University of North Texas Michael Fanelli Black Holes, Quasars, and Galaxies $67,208 The University of Texas at Austin Gregory Shields Three-Dimensional Electric Confinement of a Thermal Ion Plasma $40,000 University of North Texas Carlos Ordonez Social and Behavioral Sciences Mujeres Sanas (Healthy Women): Virtual Bridges for the 21st Century $100,000 University of North Texas Ruthann Masaracchia Sensory Influences in Early Speech Acquisition $96,000 The University of Texas at Austin Barbara Davis Mechanisms of Perceptual Clarity during Object Motion and Eye Movements $85,750 University of Houston Harold Bedell; Haluk Ogmen Visual Memory for Moving Scenes and Implications for Transportation Safety $79,400 Texas Tech University Patricia DeLucia Species Recognition versus Mate-Quality Recognition $78,895 Southwest Texas State University Caitlin Gabor The Economic Impact of Windstorms and Mitigation on Texas Labor Markets $65,760 Texas Tech University Bradley Ewing; Jamie Kruse Economic Basis for Identifying and Pricing Dynamic Digital Documents $49,000 The University of Texas at Austin Andrew Whinston Measuring the Competitiveness of Deregulated Electricity Markets $48,853 Texas A&M University Steven Puller Colonial and Community History: The Rehabilitation of an Historic Spanish Mission in Socorro, Texas $47,988 The University of Texas at El Paso Howard Campbell C-7 Advanced Technology Program 2001 Funded Projects Aerospace Autonomous Spacecraft Navigation $250,000 Texas Engineering Experiment Station John Junkins; Johnny Hurtado Intelligent Decision Making for Robot Human Cooperation $250,000 The University of Texas at Austin Delbert Tesar; Chetan Kapoor Radiation Tolerant and Ultra Efficient Multijunction Quantum Well Solar Cell for Spacecraft $234,700 University of Houston Alex Freundlich Unified Methods for Turbulence Simulation $200,000 Rice University S. Scott Collis Artificial-Gravity-Generating Tethered Satellite System with Student Participation Program $159,800 The University of Texas at Dallas John Hoffman $40,000 Texas Christian University Andre Mazzoleni Alteration in Bacterial Virulence and Host Responses under Simulated Microgravity $180,000 UT Medical Branch at Galveston Ashok Chopra; Vimlarani Chopra Covariance Control in Space Surveillance $150,000 Texas Engineering Experiment Station Kyle Alfriend Near Zero-g Active Vibration Isolation for Microgravity Experiments $110,920 University of Houston Karolos Grigoriadis $39,080 University of Houston – Downtown Weining Feng Agriculture/Aquaculture/Agricultural Biotechnology Biological Activities of Citrus Flavonoids $49,926 The University of Texas at Austin Jennifer Brodbelt $49,296 TAMU System Health Science Center Edward Miller $49,926 The University of Texas – Pan American Hassan Ahmad $49,926 Texas Agricultural Experiment Station Nancy D. Turner $49,926 Texas A&M University – Kingsville Bhimanagouda Patil Antisense Approach to Reduce Gossypol in Cottonseed $215,284 Texas Agricultural Experiment Station Jean Gould Genetically Engineered Synthesis of Taxol $210,000 Texas Agricultural Experiment Station Alastair I. Scott Development of Novel Therapeutics to Prevent and Control Foot-and-Mouth Disease $200,000 UT Medical Branch at Galveston Stanley Watowich Comparative and Functional Genomics of the Bovine Major Histocompatibility Complex $199,300 Texas Agricultural Experiment Station James Womack; Loren K. Skow Functional Genomics of Fiber Development in Cotton $196,500 Texas Agricultural Experiment Station Z. Jeffrey Chen; David M. Stelly Sustainability of Systems for Manure Export and Water Quality Improvements on Impaired Watersheds $106,231 Texas Agricultural Experiment Station Donald M. Vietor; Clyde Munster $85,170 Tarleton State University Anne McFarland Generating Conditional FMDV Resistance in Cattle by Inducible Ribozyme Degradation of IRES RNA. $188,500 Texas Agricultural Experiment Station Patrick Dunne; Jorge Piedrahita Creating Drought-, Salt-, and Chilling Temperature-Tolerant Cotton for West Texas $185,000 Texas Tech University Hong Zhang; Scott Holaday Development of an Early Warning System for Sorghum Ergot Using Doppler Radar and the NPET Network $175,000 Texas Agricultural Experiment Station Charles M. Rush; Fekeda Workneh Validation of Beef Carcass Decontamination by Organic Acids (declined) $170,650 Texas Agricultural Experiment Station Gary Acuff; Jeff Savell Development and Use of Hypervariable DNA Markers to Enhance Aquaculture of Morone Hybrids $168,973 Texas Agricultural Experiment Station Delbert M. Gatlin; John R. Gold Drought Tolerant Pines for Texas Forests $160,000 Texas Agricultural Experiment Station Carol Loopstra Satellite Virus Vectors as Peptide Delivery Vehicles $150,000 Texas Agricultural Experiment Station Karen-Beth Scholthof Reducing Odors and Flies at Texas Cattle Feedyards $148,369 West Texas A&M University David Parker; Greta Schuster C-8 Identification, Mapping, and Pyramiding of Leaf Rust Resistance Genes in Wheat $147,000 Texas Agricultural Experiment Station Jackie Rudd; John E. Mullet Novel Biomechanical Methods for Characterizing Beef Tenderness $138,416 Texas Agricultural Experiment Station Rhonda Miller; Jimmy T. Keeton Sustainable Cultivated Pasture Systems for Texas Meat Goats $66,617 Texas Agricultural Experiment Station James P. Muir $52,483 Angelo State University Rod Reed Impact of High-Speed Chilling/Freezing Immersion on Microbial and Sensory Quality of TX Cantaloupe $121,800 Texas Tech University Leslie Thompson; Linda Hoover Development of Insect Neuropeptide-Based Insect Control Agents $99,000 Texas Agricultural Experiment Station Howard Williams Irrigation, Remote-Sensing and Tillage Management for Pepper and Cotton $97,760 Texas Agricultural Experiment Station Daniel I. Leskovar; Giovanni Piccinni Biomedicine Development of Activation-State Specific Somatostatin Receptor Antibodies for Tumor Diagnosis $275,000 UT Health Science Center at Houston Agnes Schonbrunn Phylogenetic Approach to the Treatment of Pollen Allergy $270,000 UT Medical Branch at Galveston Randall Goldblum Novel Optoacoustic Imaging System for Early Detection and Image Guided Biopsy of Prostate Cancer $250,000 UT Medical Branch at Galveston Alexander Oraevsky; Massoud Motamedi Development of Novel System for Drug Delivery in Tumors $230,000 UT Medical Branch at Galveston Rinat Esenaliev A Virtual Reality Based Minimally Invasive Surgery Trainer $225,000 The University of Texas at Arlington Venkat Devarajan Combinatorial Syntheses of Peptidomimetics for Affinity Purifications of Antibodies $225,000 Texas A&M University Kevin Burgess Molecular Characterization of Human Cardiac Stem Cells $220,000 UT Southwestern Medical Center at Dallas Daniel Garry Peptide Vaccination for Autoimmune Myasthenia Gravis $220,000 UT Medical Center at Galveston Premkumar Christadoss Reverse Molecular Genetic Analysis of Hepatitis C Virus Replication: Toward Rational Drug Design $220,000 UT Medical Branch at Galveston Stanley Lemon; Minkyung Yi A Novel Gene, Capillary Morphogenesis Gene-2, Regulates Angiogenic Responses in Three Dimensions $200,000 TAMU System Health Science Center George Davis A Test for HERG Blockers Based on Heterologous Expression in “C elegans” $200,000 UT Southwestern Medical Center at Dallas Leon Avery; James Waddle Coactivator Antisense Oligonucleotides as Therapeutic Agents for Breast Cancer $200,000 Baylor College of Medicine Carolyn Smith Development of Pituitary Stem Cells as Therapeutic Agents for Pituitary Deficiencies $200,000 Baylor College of Medicine Kathleen Mahon Dietary Interactions to Inhibit Mammary Cancer $200,000 The University of Texas at Austin Kimberly Kline; Bob Sanders Gene-Directed Enzyme Prodrug Therapy $200,000 UT M.D. Anderson Cancer Center David Farquhar Genetic Targeting of Adenoviral Gene Transfer into Tumors $200,000 UT Southwestern Medical Center at Dallas Robert Gerard Human Heart Failure: Directed by Alternative Spliced Serum Response Factor, SRFdelta5 $200,000 Baylor College of Medicine Robert Schwartz; Lei Wei New Approaches for Cell-Specific Targeting of Lung Cancer $200,000 UT Southwestern Medical Center at Dallas Kathlynn Brown Specific Coagulation of Tumor Vasculature $200,000 UT Southwestern Medical Center at Dallas Philip Thorpe Therapeutic Targets for Treatment of Heart Failure and Cardiac Enlargement $200,000 UT Southwestern Medical Center at Dallas Eric Olson ECE Inhibitors: Ocular Neuroprotective Agents $198,000 UNT Health Science Center at Fort Worth Thomas Yorio Development of Molecular Markers for Atherosclerosis Using High Throughput Proteomics $190,000 Baylor College of Medicine Christie M. Ballantyne C-9 Methods for Generating Kidney Tubules from Stem Cells $180,000 UT Southwestern Medical Center at Dallas Peter Igarashi Development of Peptide Aptamers on Display Phage for the Treatment of CDAD $150,000 TTU Health Sciences Center Joe Fralick MT Contrast Agents: A New Paradigm in Molecular Imaging $150,000 The University of Texas at Dallas Dean Sherry Imaging of Cellular Processes in vivo Using Fullerenes $140,000 Baylor College of Medicine David Baskin Inhibition of Renal Fibrosis by Targeting SMAD Signaling Using Ultrasound Gene Therapy Technique $135,000 Baylor College of Medicine Hui Lan Antibiotics Designed to Defeat Resistant Organisms $100,000 Southern Methodist University John Buynak Clinical Trial of Oral Interferon Alpha in Idiopathic Pulmonary Fibrosis $100,000 TTU Health Sciences Center Lorenz Lutherer; Cynthia Jumper Comprehend Before You Consume: Product Information Labels to Improve Over-the-Counter Drug Selection $90,000 University of Houston Sujit Sansgiry Computer and Information Engineering A Framework for Generating High-Level Programming Systems, Applied to Multimedia Communications $200,000 Rice University Ken Kennedy Resource Management for Safe Deployment of Edge Services $125,000 Rice University Dan Wallach $125,000 The University of Texas at Austin Michael Dahlin Compiler Support for Beowulf Clusters $249,507 Rice University John Mellor-Crummey Geometry, Connectivity, and Simulation of Cortical Networks $240,400 Texas Engineering Experiment Station Nancy Amato; Lawrence Rauchwerger Text Mining for the Telecommunications Industry $228,900 The University of Texas at Dallas Dan Moldovan Pastry: A Generic Substrate for Large-Scale, Decentralized, Distributed Applications $228,162 Rice University Peter Druschel; Alan Cox Strategic Autonomy for Planetary Rovers $199,960 The University of Texas at Austin Benjamin Kuipers Exploring the Brain Forest $199,644 Texas Engineering Experiment Station John Keyser; Bruce McCormick Massively Multi-Person, Dynamic Virtual Environments $197,696 Rice University Joe Warren A Component System for Java Based on Generic Types $197,444 Rice University Robert Cartwright A Browser for Visual Content $153,300 The University of Texas at Dallas Haim Schweitzer Resource Management in Server Clusters $150,000 The University of Texas at Austin Lorenzo Alvisi; Harrick Vin Parallel Algorithms and Software for Delay Estimation in VLSI Circuits $149,993 Texas Engineering Experiment Station Vivek Sarin; Weiping Shi Integrating Design Verification Techniques with Defect-Oriented ATPG for Very Deep Submicron Systems $139,720 Texas Engineering Experiment Station Ray Mercer NetTomo: A Software Tool for Network Tomography $130,540 Rice University Robert Nowak Ensuring and Maximizing Reliability and Safety for Embedded Software Systems $115,540 Southern Methodist University Jeff Tian On the Statistical/Bio-physical Extraction of Textural Features of Imagery Databases $100,000 Texas Engineering Experiment Station Jyh-Charn Liu; Yoonsuck Choe System for Developing Efficient Power-Load Forecasters $96,000 The University of Texas at Arlington Michael T. Manry Energy Improved Oil Recovery Efficiency by Gas Injection $249,808 The University of Texas at Austin Russell Johns; Larry Lake C-10 CO-Free Hydrogen for Fuel Cells via Stepwise Reforming of Hydrocarbons $228,085 Texas A&M University David Goodman Novel High Efficiency Thermophotovoltaic Device for Direct Heat to Electricity Conversion $226,000 University of Houston Charles Horton Photoelectrochromic “Smart” Windows for Energy-Efficient Buildings $197,600 The University of Texas at Arlington K. Rajeshwar Development of a Low Cost Inverter for Fuel Cell Power Systems $194,298 Texas Engineering Experiment Station Prasad Enjeti Chemical Liquefaction of Biomass to Hydrocarbon Fuels: Continuous Electrochemical Reduction $175,000 The University of Texas of the Permian Basin J. Michael Robinson Microtomographic Study for Carbonate Petrophysics $107,100 University of Houston K. K. Mohanty $54,000 University of Houston – Clear Lake Liwen Shih Improved Catalytic Combustion System $150,000 University of Houston James Richardson Nanostructured Hybrid Membranes for High Temperature Fuel Cells $149,995 The University of Texas at Dallas John Ferraris; Kenneth Balkus Engine Friction Reduction $149,892 The University of Texas at Austin Ron Matthews 3-D Seismic Attribute Analysis of the Devonian Thirty-One Chert Depositional System, Tobosa Basin, TX $145,600 University of Houston Kurt Marfurt; Charlotte Sullivan Increased Electricity Supply through Real-Time Power System Monitoring and Control $141,000 Texas Engineering Experiment Station Carl Benner; B. Don Russell Effects of Sea Water and Reservoir Brines on Gas Hydrate Formation $101,500 Texas Engineering Experiment Station Yuri Makogon Biodesulfurization of Recalcitrant Organosulfur Compounds $100,000 Southwest Texas State University Linette Watkins; Walter Rudzinski Increased Energy Efficiency of Fluorescent Lamps $98,000 Texas A&M University Robert Kenefick; Eilliam Bassichis Smart, Utility-Connected Inverters for Solar Power Panels $72,300 Texas Tech University Michael Giesselmann Inversion of Gravity Gradient Data, a New Tool in the Exploration and Production of Hydrocarbons $45,150 Rice University Manik Talwani Environmental Science and Engineering, Recycling, and Water Resources Bioengineering a Fungus for Enhanced Degradation of Volatile Organic Contaminants $297,700 The University of Texas at Austin Kerry Kinney; Chris Whitman Fuel Efficient and Low Emissions Fuel Cell Powered Vehicle $288,000 Texas Tech University Timothy Maxwell Improved Aquifer Characterization Using Hydraulic Tomography $275,600 Texas A&M University Brann Johnson; Mark Everett Hydrology and Salinity Monitoring and Modeling Along the Middle Rio Grande $212,500 Texas Agricultural Experiment Station Ranjin Muttiah; Seiiche Miyamoto Phase Transfer Catalytic Process for in situ Remediation of Underground Contaminants $106,250 Southwest Texas State University Larry Britton $106,250 The University of Texas at Austin Gary Pope Development of a Rapid Whole-Cell, Green-Fluorescent, Protein-Based Biosensor for Assessing Lysine $200,000 Texas Agricultural Experiment Station Steven C. Ricke Removal of Trihalomethanes from Drinnking Water by Cometabolism in Nitrifying Biofilters $199,935 The University of Texas at Austin Gerald Speitel Integrated Catalytic Filtration Devices for Diesel Exhaust Abatement of NOx and Particulates $199,300 University of Houston Michael Harold Antibody-Based Assays to Monitor Chemical Exposure $198,416 UT Medical Branch at Galveston M. Firoze Khan; Ghulam Ansari Environmental Viruses $160,000 UT Health Science Center at San Antonio Philip Serwer; Stephen Hardies Development of a High-Performance Airborne Remote-Sensing System for Water Resources Research $159,223 Texas Tech University Stephan Maas; Thayne Montague Detection of Airborne Mycotoxins Produced by Fungi in “Sick” Building $150,000 TTU Health Sciences Center David Straus; James Hutson C-11 Optimizing Emission Reduction Strategies for Refineries and Chemical Manufacturing Facilities $150,000 The University of Texas at Austin David Allen A Real-Time Drought Assessment and Forecasting System for Texas Using GIS and Remote Sensing $149,920 Texas Agricultural Experiment Station Raghavan Srinivasan Enhanced Degradation of Environmental Contaminants Using Pulsed and Heterodyne Sonochemistry $149,501 Texas Tech University Dominick Casadonte Real-Time Distributed Modeling of Flood Events Using NEXRAD Precipitation Data $148,500 Texas Agricultural Experiment Station William Dugas Application of High-Activity Modified Green Rusts for Treatment of Water and Wastewater $146,697 Texas Engineering Experiment Station Bill Batchelor Novel Reactor and Catalyst Designs for Ultra-Low Vehicular Emissions $146,000 University of Houston Vemuri Balakotaiah Development of Diode-Laser-Based Sensors for Nitric Oxide and Nitrogen Dioxide $145,580 Texas Engineering Experiment Station Robert Lucht Pretreatment for Reverse Osmosis Membranes: Silica Removal to Increase Yield in Border Region $139,650 The University of Texas at Austin Desmond Lawler Carbon Dioxide Capture by Absorption with Potassium Carbonate $135,340 The University of Texas at Austin Gary Rochelle Application of Cell Recognition Technology to Environmental Studies of Harmful Algal Blooms $122,000 The University of Texas at Austin Edward Buskey Conservation of Nitrogen and Phosphorus in Open-Lot Cattle Feedyards $71,780 Texas Agricultural Experiment Station Wayne Greene $27,720 West Texas A&M University David Parker Manufacturing Technology Manufacturing of Affordable Single Use Bio-MEMS $391,500 The University of Texas at Arlington Shiv P. Joshi; Panayiotis S. Shiakolas Surface Wave Plasmas for Next-Generation Integrated Circuit Manufacturing $298,800 University of Houston John Wolfe; Michael Gorman Integrated Multidimensional Positioning Technology for Precision Manufacturing Equipment $249,999 Texas Engineering Experiment Station Won-jong Kim; Suhada Jayasuriya Prediction of Flash Points for Flammable Liquid Mixtures $162,000 Texas Engineering Experiment Station James Holste; William Rogers $87,608 Prairie View A&M Universityq Irvin Osborne-Lee Development of Information System for Hybrid Rapid Manufacturing Process $200,000 Southern Methodist University Radovan Kovacevic Design of Assembly Systems and Their Supply Chains to Promote Business Development under the NAFTA $199,992 Texas Engineering Experiment Station Wilbert Wilhelm Fabricating Photonic Nano-Composites $190,900 The University of Texas at Austin Michael Becker; John Keto Tools for the Design and Control of Hollow Fiber Spinning Systems $171,080 The University of Texas at Austin Roger Bonnecaze CyPhy: Direct Instrumentation of Product Prototypes $150,000 The University of Texas at Austin Kristin Wood; Matthew Campbell Nano-Precision Large Displacement Flexure Machines for Vacuum-Based Semiconductor Equipment $150,000 The University of Texas at Austin S. V. Sreenivasan Customized X-Ray Microtomographic Image Analysis for Measurement in Cotton-Based Industries $149,987 Texas Tech University Hamed Sari-Sarraf; Eric Hequet Extracting and Visualizing Manufacturing Variability Information from Coordinate Metrology Data $149,900 Texas Engineering Experiment Station Daniel Apley; Amarnath Banerjee Fault Diagnostics and Prognosis of Industrial Equipment using Information Theory Tools $149,656 The University of Texas at Austin Benito Fernandez; Michael Bryant Novel Fluorescent Diagnostics for Industrial Mixing Processes $135,000 Texas Engineering Experiment Station Lynn Melton Materials Technology Applications of Carbon Nanotubes, Fluoronanotubes and Nanocrystals of Diamond and C3N4 $300,000 Rice University John L. Margrave Development of Wireless Sensors to Monitor Corrosion in Civil Infrastructure Systems $300,000 The University of Texas at Austin Dean Neikirk; Sharon Wood C-12 Materials Development of Polymer Photonic Crystals for Integration with III-V Nanostructure Devices $280,000 The University of Texas at Austin Dennis Deppe; Ray Chen Developing a New Ruthenium-Based Diffusion Barrier for Copper Interconnects $264,890 University of North Texas Oliver Chyan; Michael Richmond Carbon Nanotube Single Crystals for Optoelectronic Devices $250,000 Rice University Junichiro Kono; Richard E. Smalley New Synthetic Methods for Metallic Alloy Nanocrystals for Ultra High Density Magnetic Recording $250,000 The University of Texas at Austin Brian Korgel; Angela Belcher Nonlinear Optical Devices Fabricated by Ionic Self-Assembled Monolayer Techniques $250,000 The University of Texas at Arlington Martin Pomerantz; Theresa Maldonado Nanotube/Polypropylene Nanocomposites for Electromagnetic Interference Shielding Effectiveness $126,805 The University of Texas – Pan American Karen Lozano $84,000 Rice University Enrique Barrera Investigation of the Rhealogical Behavior of Metallocene Polymers $76,000 Texas Engineering Experiment Station K. R. Rajagopal $124,000 Texas Tech University Gregory McKenna Ultrathin HfO2 and ZrO2 Gate Dielectrics for 70 nm Technology Applications $200,000 The University of Texas at Austin Jack Lee Nanoshell Based All-Optical Sensors and Devices $199,996 Rice University Naomi Halas Carbon Nanotube Arrays for Field-Emission Display Applications $192,800 The University of Texas at Austin Chih-Kang Shih; Zhen Yao Novel Ferroelectric and Functional Thin Films for Information Technology $185,000 Rice University Susanne Stemmer Newly Discovered Radiation Detector: Nanometer-Size Liquid Crystal Droplets Dispersed in Polymer $150,000 The University of Texas at Arlington Suresh C. Sharma An Automated System to Prepare and Process Cross-Sectional Specimens from Three-Dimensional Objects $149,658 UT Health Science Center at San Antonio David Carnes Domain Wall Phenomena in Magnetic Thin Film Microstructures $140,000 The University of Texas at Austin James Erskine The Development of Nanostructured Hydrogels for Controlled Delivery of Bioactive Compounds $134,303 University of North Texas Zhibing Hu Development of Design Tools for Nanoengineered Photonic Devices $97,100 Rice University Peter Nordlander Medical Biotechnology Polymeric Carriers for Molecularly Targeted Diagnostic Agents for Near-Infrared Optical Imaging $140,428 UT M.D. Anderson Cancer Center Chun Li $104,018 Texas Engineering Experiment Station Eva Sevick Isolation of a Gene which Marks Tamoxifen Resistance of Breast Tumors $240,000 Baylor College of Medicine Bert O’Malley Transabdominal Magnetic Anchoring System for Trocar-less Laparoscopic Survery $70,875 UT Southwestern Medical Center at Dallas Jeffrey Cadeddu; Robert Eberhart $154,125 The University of Texas at Arlington Raul Fernandez Metabolic Engineering to Produce Terpenes $210,000 Rice University Seiichi Matsuda An “At Risk” Immunoassay for Alzheimer’s Disease Based on Specific Oxidized Plasma Proteins $200,000 UNT Health Science Center at Fort Worth Robert Gracy Bacteriophage Genes as the Basis for New Antibiotics $200,000 Rice University Charles Stewart Cancer Genomic Vaccines $200,000 UT Southwestern Medical Center at Dallas Stephen Johnston Novel Scaffold Design and Evaluation Technique for Engineering Bone Replacement Tissue $187,500 Rice University Michael Liebschner; Antonios Mikos Computational Model of the Control of Gene Expression – A Method for Novel Drug Target Discovery $184,035 The University of Texas at Dallas Mohsin Jafri Genetically Modified Bone Marrow Stromal Cell Transplantation for Aging-Related Neuronal Degeneration $176,792 Baylor College of Medicine Keyi Yang Rapid Detection of Drug Resistant Mycobacterium Tuberculosis Using Two-Dimensional Gene Scanning $176,500 UT Health Science Center at San Antonio Rebecca Cox; Teresa Quitugua C-13 Light-Directed Control of Multicellular Assemblies ex vivo $170,000 UT Southwestern Medical Center at Dallas Kevin Luebke Biomechanics and the Treatment of Cataracts $80,235 Texas Engineering Experiment Station Jay Humphrey $22,400 Texas Agricultural Experiment Station Joan Dziezyc Chemoprevention of Skin Cancers by Novel Derivatives of Tempol in Mice and Cultures $100,000 University of Houston Diana Chow Improvements to the Cofocal Microscope $83,804 UNT Health Science Center at Fort Worth Julian Borejdo Microelectronics Self-Assembled Silicide Nanostructures for Integrated Optoelectronics $239,000 University of North Texas Jose M. Perez; Terry Golding Integrated TE Microcooler and Mid-IR Laser for Chemical Sensing Applications $237,320 University of Houston Shin-Shem Steven Pei Metal Gate Electrodes for High-k Dielectric Stacks $180,392 University of North Texas Robert M. Wallace $49,608 University of Houston Len Trombetta Polymer-Derived Nanowires for Integrated Circuit Strategies $200,000 Southwest Texas State University Heather Galloway; Patrick Cassidy Integration of Molecular Electronics with Scaled Silicon CMOS $199,666 University of North Texas Bruce Gnade Efficient Monolithic WDM Components at 1550 nm $181,618 Southern Methodist University Jerome Butler Mid-Infrared Optoelectronic Devices $169,490 The University of Texas at Austin Ben Streetman; Archie Holmes High-Speed Photodetectors for 40 GB/s Fiber Optic Receivers $150,000 The University of Texas at Austin Joe Campbell Low Power, High-Speed, Dense Flash Memories Using SiGe/C Heterostructures and Quantum Dot Gates $149,950 The University of Texas at Austin Sanjay Banerjee Compact, Scalable Computer Models for Noise in Advanced CMOS and Bipolar Technologies $148,290 Southern Methodist University Zeynap Celik-Butler Telecommunications Phase-Controlled Imaging with Digital Light Processing $250,000 UT Southwestern Medical Center at Dallas Harold Garner Electrooptics Technology for Fiber Optics Networks $200,000 Texas Engineering Experiment Station Henry Taylor; Ohannes Eknoyan Single Event Upset in Integrated Circuits, Studied with a Newly Developed Nanoprobe $200,000 University of North Texas Floyd McDaniel; Jerome Duggan Compact Antenna System for Mobile Satellite Communication $199,467 Southern Methodist University Choon Lee Delivering High Perceptual Quality Real-Time Video over Wireless Networks $194,303 Rice University Richard Baraniuk; Edward Knightly Direct Write of Optical Components $150,000 The University of Texas at Austin Joseph Beaman; Harovel Wheat Scannable Antennas for LMDS Applications $150,000 University of Houston David Jackson QoS (Quality of Service) Supported Communication Schemes in Mobile Wireless Networks $149,900 Texas Engineering Experiment Station Mi Lu Network Architectures Based on Partial State $82,100 Texas Engineering Experiment Station Narasimha Reddy $67,700 Texas A&M University Marina Vannucci ASIC Design and Implementation of Advanced Coding Techniques for Next Generation Wireless Networks $142,252 Texas Engineering Experiment Station Gwan Choi; Krishna Narayanan DSL to 802.11 Bridge: Enabling High-Speed Wireless Internet Access at Home and Small Offices $127,500 The University of Texas at Austin Brian Evans; Robert Heath Maximizing Profitability of QoS-Based Packet-Switched Telecommunications Networks $102,884 Southern Methodist University Richard Helgason Analytic and Simulation Tools for Wireless Data Networks $78,200 Texas Engineering Experiment Station Scott Miller C-14 Transportation The Design of a New Generation of Traffic Noise Barriers – Continuing Investigation $198,800 The University of Texas at Austin David Blackstock Forecasting Highway Bridge Deterioration under NAFTA Truck Traffic $135,000 Texas Transportation Institute Laurence Rilett; Gary Fry Development of a Non-Contact Sensor for Measurement of Highway Pavement Skid Number $99,733 University of Houston Richard Liu C-15 Advanced Technology Development and Transfer 2001 Funded Projects Aerospace Hall Thruster Satellite Communication Impact Analysis $190,000 The University of Texas at Austin Match: $250,000 Lockheed Martin Corp.; Sunnyvale, CA Gary Hallock; James Wiley Agriculture/Aquaculture/Agricultural Biotechnology Development of High-Yielding Drought-Tolerant Cotton $185,000 Texas Tech University Randy Allen; David Tissue Match: $300,000 Syngenta; Basel, Switzerland Exploiting Transgenic Cotton with Improved Yield and Fiber Quality $175,533 Texas Tech University Candace Haigler; Scott Holaday Match: $720,000 Aventis CropScience GmbH; Frankfurt, Germany Testing Novel Inhibitors that Enhance the Biocidal Action of Herbicides $150,000 The University of Texas at Austin Stanley Roux; Alan Lloyd Match: $75,000 Biagro Western Sales, Inc.; Visalia, CA $75,000 Intracrop-Brian Lewis Agriculture Ltd.; North Yorkshire, England Fetal Wastage Tritrichomonas Foetus Diagnosis Development $100,000 UT Health Science Center at San Antonio John Alderete March: $100,000 Xenotope Diagnostics, Inc.; San Francisco, CA Biomedicine Chemical Vaccination Against HIV $300,000 UT Health Science Center at Houston Sudhir Paul Match: $2,100,000 Hesed Biomed; Omaha, NB Polyethyeneimine-Gene Therapy Given by Aerosol: An Effective Treatment for Pulmonary Metastases $118,973 Baylor College of Medicine Charles Densmore $126,027 UT M.D. Anderson Cancer Center Eugene Kleinerman Match: $249,992 JAGO Research AG (Subsidiary of SkyePharma AG); Muttenz, Switzerland Identification of Telomerase Regulatory Genes as Potential Anticancer Targets $119,256 Texas A&M University Thomas McKnight $100,744 Texas Agricultural Experiment Station Dorothy Shippen Match: $226,000 Geron Corporation; Menlo Park, CA Treatment Planning Software for Electron Conformal Therapy Using Bolus $220,000 UT M.D. Anderson Cancer Center Kenneth Hogstrom; John Antolak Match: $250,000 Computerized Medical Systems, Inc.; St. Louis, MO Transplantation of Bone Marrow Mesencymal Stem Cells in Dog Hearts with Myocardial Infarction $200,000 UT Health Science Center at Houston Yong-Jian Geng Match: $250,000 Osiris Therapeutics, Inc.; Baltimore, MD In vivo Confocal Microscopy for Pre-Cancer Detection $138,000 The University of Texas at Austin Rebecca Richards-Kortum $60,000 UT M.D. Anderson Cancer Center Michele Follen Match: $200,000 Lucid, Inc.; Rochester, NY Evaluation of Antitumor and Antiangiogenic Properties of a Novel Gene, MDA-7 $100,000 UT M.D. Anderson Cancer Center Rajagopal Ramesh Match: $100,000 Introgen Therapeutics, Inc.; Houston, TX Computer and Information Engineering SmartWeb: A Next-Generation Web Infrastructure $190,000 Rice University Match: $90,000 IBM Austin Research Lab; Austin, TX $100,000 Compaq Computer; Palo Alto, CA Peter Druschel; Willy Zwaenepoel D-1 A Digital Multispectral Stereo Image Analyzer for Prevention of Early Blindness from Retinopathy $150,000 Texas Tech University Sunanda Mitra Match: $160,000 Kestrel Corporation; Albuquerque, NM Energy Core Proton Exchange Membrane Fuel Cell Technology Transfer $200,000 Texas Engineering Experiment Station John Appleby Match: $295,000 Reliant Energy Power Systems, Inc.; Houston, TX Sensorless Switched Reluctance Motors for Efficient Pumps and Compressors $200,000 Texas Engineering Experiment Station Mehrdad Ehsani Match: $300,000 Anacon Systems, Inc.; Austin, TX Ultra-High Concentration HF Treatments for Stimulating Oil and Gas Recovery $198,900 The University of Texas at Austin Ding Zhu; A. D. Hill Match: $200,000 BJ Services Company; Tomball, TX Low Cost, High-Accuracy, Slotted-Orifice, Multi-Phase Flowmeter $99,900 Texas Engineering Experiment Station Gerald Morrison Match: $100,000 Flowline Meters, Inc.; Mont Belview, TX Environmental Science and Engineering, Recycling, and Water Resources Extension of HF Radar for Water Currents and Direct Observation of Transport Model Coefficients $123,653 Texas A&M University – Corpus Christi James Bonner $85,000 The University of Texas at El Paso Rosa Fitzgerald Match: $45,000 Exxon Mobile Research and Engineering; Fairfax, VA $205,000 CODAR Ocean Sensors, Ltd.; Los Altos, CA Quantum Cascade Laser-Based Gas Sensors for Chemical and Environmental Analysis $115,000 Rice University Frank Tittel; Robert Curl Match: $115,000 Analytical Specialties, Inc.; Houston, TX Manufacturing Technology Selective Laser Sintered and Silicon-Infiltrated Silicon Carbide Boats $200,000 The University of Texas at Austin David Bourell; Kristin Wood Match: $245,000 Si.C. Innovation; Elgin, TX Containerless Processing of Nanotube Reinforced Metal Matrix Nanocomposites $150,000 Rice University Enrique Barrera; Yildiz Bayazitoglu Match: $110,000 NanoTechnologies of Texas, Inc.; Houston, TX $90,000 Stewart Automotive Research, LLC; Houston, TX Manufacture of Improved Thermoelectric Materials $148,833 Texas Engineering Experiment Station K. T. Hartwig Match: $148,833 Marlow Industries, Inc.; Dallas, TX A Low-Cost Parallel Tester for Increasing Mixed Signal Semiconductor Test Time Efficiency $142,800 Texas Engineering Experiment Station Rainer Fink; Jay Porter Match: $136,400 National Instruments; Austin, TX $135,000 Texas Instruments; Dallas, TX Materials Technology Environmentally Friendly High Performance Lubricants and Anti-Icing Aircraft Coatings $235,000 The University of Texas at Arlington Ronald Elsenbaumer; Pranesh Aswath Match: $250,000 Platinum Research Organization, LLC; Dallas, TX Medical Biotechnology Thin Film Optical Detectors (TOD) for Retinal Implantation – A “Bionic” Eye $398,000 University of Houston Alex Ignatiev Match: $500,000 CIBCO Technologies, LLC.; Houston, TX $160,000 St. Joseph Hospital; Houston, TX Development of Advanced Time-of-Flight (TOF) Mass Spectrometry $300,000 Texas A&M University David Russell Match: $463,600 Ionwerks; Houston, TX D-1 Blood Test to Detect Cancer $295,348 UT Southwestern Medical Center at Dallas Jonathan Uhr Match: $460,000 Immunicon Corporation; Huntingdon Valley, PA Commercialization of a Novel Family of Nitrogen-Free Reagents for Biomedical Analysis $199,200 Texas A&M University Gyula Vigh Match: $477,009 ANTEK Instrument, LP; Houston, TX Dermatological Laser Therapy: Advancing the Technology to Treat Patients of All Skin Types $60,000 Rice University Bahman Anvari $60,000 UT M.D. Anderson Cancer Center David Chang Match: $120,000 Candela Corporation; Wayland, MA The Optical Stretcher – A Novel Cytological Device for Early Cancer Diagnosis $100,000 The University of Texas at Austin Josef Kas Match: $275,000 Evacyte Corporation; Austin, TX Advanced Neuroprosthetic Multiple Electrode Arrays Using MEMS Technology $54,900 The University of Texas at Dallas Lawrence Cauller Match: $6,900 Plexon, Inc.; Dallas, TX $48,000 Zyvex Corporation; Richardson, TX Microelectronics Bandwidth Enhanced Fully Embedded Optoelectronically Interconnected Processor-to-Memory Links $298,000 The University of Texas at Austin Ray Chen; Gerald Lipovski Match: $200,000 Pacific Wave Communications; Los Angeles, CA $85,000 ITRI; San Jose, CA $150,000 Intel Corp; Hillsboro, OR $200,000 Applied Materials; Austin, TX $200,000 Texas Instruments, Inc.; Dallas, TX Commercialization of Low-Cost, Surface-Emitting Semiconductor Lasers at 1310 and 1550 nm $242,225 Southern Methodist University Gary Evans Match: $25,000 MicroFab Technologies, Inc.; Plano, TX $1,510,720 Photodigm, Inc.; Dallas, TX Development of Next Generation VLSI Technology for Very High Speed Analog Chip Design $200,000 The University of Texas at Arlington Ronald Carter; W. Alan Davis Match: $200,000 National Semiconductor Corporation; Santa Clara, CA Telecommunications Development of an IEEE 802.11 Platform to Support Delay-Sensitive Applications in Wireless LANs $223,000 Rice University Behnaam Aazhang; Edward Knightly Match: $280,000 Nokia; Irving, TX $150,000 Texas Instruments Inc.; Dallas, TX Photonic Switching with Digital Micromirror Arrays $150,000 Texas Tech University Henry K. Temkin; Jordan Berg Match: $150,000 Texas Instruments, Inc.; Plano, TX Transportation Active Suspension for Improved SUV Safety $257,280 The University of Texas at Austin $41,600 The University of Texas – Pan American Match: $250,000 Stewart and Stevenson; Sealy, TX $300,000 Litton; Toronto, Ontario $4,000 Ford Center for Excellence; Austin, TX Steven Nichols Robert Freeman D-1 Appendix D Funding by Institution Number of Projects* Institution Angelo State University Baylor College of Medicine Midwestern State University Prairie View A&M University Rice University Southern Methodist University Southwest Texas State University TAMU System Health Science Center Tarleton State University Texas A&M University Texas A&M University-Corpus Christi Texas A&M University-Kingsville Texas Agricultural Experiment Station Texas Christian University Texas Engineering Experiment Station Texas Tech University TTU Health Sciences Center Texas Transportation Institute University of Houston University of Houston-Clear Lake University of Houston-Downtown University of North Texas UNT Health Science Center at Fort Worth The University of Texas at Arlington The University of Texas at Austin The University of Texas at Dallas The University of Texas at El Paso The University of Texas-Pan American The University of Texas of the Permian Basin The University of Texas at San Antonio UT Health Science Center at Houston UT Health Science Center at San Antonio UT M. D. Anderson Cancer Center UT Medical Branch at Galveston UT Southwestern Medical Center at Dallas West Texas A&M University TOTALS 1 9 1 1 24 8 8 2 1 23 1 1 30 1 40 23 6 2 37 1 2 10 7 14 79 12 5 3 1 1 4 7 12 10 19 2 407 Dollars 52,483 1,600,765 66,000 87,608 4,219,368 1,290,024 510,389 249,296 85,170 3,176,130 123,653 49,926 4,069,895 40,000 6,105,203 3,145,244 917,493 151,452 5,606,585 54,000 89,080 1,540,579 1,223,264 2,561,199 12,630,501 1,702,442 424,756 218,331 175,000 98,000 916,806 1,011,074 1,751,886 2,139,299 3,553,250 176,089 $62,059,351 *Joint proposals are counted multiple times -- once for each institution participating in the proposed project. The number of funded projects is 371. D-1 Appendix E Comparison of Awards in 1997, 1999, and 2001 Number of Proposals Funded by Area Advanced Research Program Astronomy Atmospheric Sciences Biological Sciences Chemistry Computer/Information Sciences Earth Sciences Engineering Marine Sciences Materials Science Mathematics Physics Social/Behavioral Sciences Advanced Technology Program Aerospace Agriculture and Aquaculture Biomedicine Biotechnology Computer/Information Engineering Energy Environmental Sciences/Engineering Manufacturing Technology Marine Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation ATP Development and Transfer Aerospace Agriculture and Aquaculture Biomedicine Biotechnology Computer/Information Engineering Energy Environmental Sciences/Engineering Manufacturing Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation TOTALS 1997 4 4 37 18 13 8 26 7 10 15 14 12 168 8 24 29 29 15 24 13 16 3 20 12 7 200 5 4 3 4 1 4 3 3 2 1 30 398 1999 49 18 13 9 32 11 15 16 13 176 8 28 33 20 15 23 24 -3 16 23 9 9 8 216 1 1 2 1 3 2 3 2 1 4 3 23 415 2001 43 16 11 7 23 9 13 12 10 144 8 20 30 18 17 23 14 18 15 10 13 3 189 1 4 7 2 4 2 4 1 7 3 2 1 38 371 E-1 Comparison of Awards in 1997, 1999, and 2001 Funding Allocations by Research Area Advanced Research Program Astronomy Atmospheric Sciences Biological Sciences Chemistry Computer/Information Sciences Earth Sciences Engineering Marine Sciences Materials Science Mathematics Physics Social/Behavioral Sciences Advanced Technology Program Aerospace Agriculture and Aquaculture Biomedicine Biotechnology Computer/Information Engineering Energy Environmental Sciences/Engineering Manufacturing Technology Marine Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation ATP Development and Transfer Aerospace Agriculture and Aquaculture Biomedicine Biotechnology Computer/Information Engineering Energy Environmental Sciences/Engineering Manufacturing Technology Materials Technology Medical Biotechnology Microelectronics Telecommunications Transportation 1997 273,357 329,652 5,744,110 2,221,727 1,714,714 916,642 3,572,523 702,577 1,528,757 747,549 1,418,142 995,410 20,065,160 1,565,183 3,941,835 5,194,244 4,635,717 2,183,157 3,359,187 3,031,427 2,722,802 565,248 3,495,187 1,872,488 1,292,633 33,859,108 568,727 731,227 313,737 981,625 156,216 821,522 845,447 462,940 443,396 201,336 5,526,173 $60,528,824 1999 * ** 6,865,320 2,202,707 1,715,153 922,398 3,903,961 1,602,389 711,161 1,568,438 1,046,924 20,538,451 1,372,924 4,348,669 6,295,990 3,138,021 2,390,776 4,172,586 3,098,443 2,995,566 4,005,585 1,636,236 1,360,505 983,591 35,798,892 175,000 194,000 365,000 83,000 750,800 447,600 345,200 783,000 285,500 746,500 551,148 4,726,748 $61,064,091 2001 * ** 7,026,363 2,250,659 1,866,180 819,180 3,900,307 1,431,280 931,860 1,373,976 691,646 20,291,451 1,614,500 3,360,403 5,768,000 3,226,806 2,585,328 4,085,862 2,836,422 3,754,522 2,700,712 1,905,334 2,094,306 433,533 34,365,728 190,000 610,533 1,483,000 340,000 698,800 323,653 641,633 235,000 1,467,448 740,225 373,000 290,880 7,402,172 $62,059,351 TOTALS * Included in Physics after 1997. ** Included in Earth Sciences after 1997. E-2 Appendix F Pre-Proposal Evaluation Forms Advanced Research Program and Advanced Technology Program Pre-proposals Each criterion is rated “poor,” “fair,” “good,” or “excellent.” 1. Technical merit and soundness of the proposal 2. Capability of personnel available to the project 3. Adequacy of physical resources available to the project 4. Student involvement and student research training opportunities Reviewer Comments Continue with Full Proposal Do Not Continue Technology Development and Transfer Pre-proposals Each criterion is rated “poor,” “fair,” “good,” or “excellent.” 1. Technical merit and soundness of the proposal 2. Capability of personnel available to the project 3. Adequacy of physical resources available to the project 4. Strength of industrial collaboration and feasibility of technology transfer plan Reviewer Comments Continue with Full Proposal Do Not Continue F-1 Fund – Priority 1 Fund – Priority 2 Do Not Fund Revise Budget Advanced Research Program ― 2001 Proposal Evaluation Form Merit and soundness of the proposal (50%) Rank (Fund – Priority 1 Proposals only) A. Scientific Base/Importance Possible Reviewer Comments: Research of far-reaching significance and based on quality, adequately referenced, scientific work Research important to development of discipline and based on quality, adequately referenced work Research important to development of discipline but based on more speculative research Research is significant in only a narrow area Research not significant within the boundaries of this competition B. Originality Possible Reviewer Comments: Original idea that looks feasible Established technique applied to new area Idea previously investigated C. Research Plan and Budget Possible Reviewer Comments: Well-documented research plan with appropriate budget and time schedule Feasible plan but proposed budget or schedule is 25% over or under what is needed to do the job Feasible plan but proposed budget or schedule is 50% over or under what is needed to do the job Poorly thought out research plan Capability of the investigator(s) (25%) D. Staff Possible Reviewer Comments: Principal investigator(s) capable of conducting outstanding research in the proposed area and qualified support personnel listed Principal investigator(s) with some experience in this area and qualified support personnel listed Principal investigator(s) with qualified support staff needed but not included Principal investigator(s) with thus far little demonstrated potential for research in this area Student involvement and research training opportunities (15%) E. Education/Training Possible Reviewer Comments: Research designed to attract, retain, and enhance the qualifications of the best students and researchers Research involves few students and provides modest training for research or innovation No student involvement in proposed research Adequacy of institutional commitment and resources (10%) F. Institutional Priority and Available Laboratory Equipment Possible Reviewer Comments: Clear institutional priority with significant institutional support and needed equipment in place Clear institutional priority with significant institutional support and equipment can reasonably be expected to be in place when needed A departmental priority with modest support and equipment can reasonably be expected to be in place when needed A topic of interest primarily to the investigator(s) and/or proposed facilities inadequate to do the job F-2 Fund – Priority 1 Fund – Priority 2 Do Not Fund Revise Budget Proposal Evaluation Form Merit and soundness of the proposal (50%) Advanced Technology Program ― 2001 Rank (Fund – Priority 1 Proposals only) A. Scientific Base/Importance Possible Reviewer Comments: Research of far-reaching significance, important to Texas, based on quality, adequately referenced, work Research important and based on quality, adequately referenced work Research important but based on more speculative technology Research is significant in only a narrow area Research not significant within the boundaries of this competition B. Originality Possible Reviewer Comments: Original idea that looks feasible Established technique applied to new area Idea previously investigated C. Research Plan and Budget Possible Reviewer Comments: Well-documented research plan with appropriate budget and time schedule Feasible plan but proposed budget or schedule is 25% over or under what is needed to do the job Feasible plan but proposed budget or schedule is 50% over or under what is needed to do the job Poorly thought out research plan D. Leveraged Funds and Technology Transfer Possible Reviewer Comments: An idea with a 70% chance of creating a major marketable product in five years and project funds are substantially leveraged from other sources An idea with a 50% chance of producing a marketable product in ten years and project funds are leveraged Prospects for leveraging of funds and/or meaningful industrial collaboration exists Project includes a meaningful collaboration An idea that is unlikely to yield a commercial product; there is no leveraging of funds and no meaningful collaboration exists E. Staff Possible Reviewer Comments: Principal investigator(s) capable of conducting outstanding research in the proposed area and qualified support personnel listed Principal investigator(s) with some experience in this area and qualified support personnel listed Principal investigator(s) with qualified support staff needed but not included Principal investigator(s) with thus far little demonstrated potential for research in this area F. Education/Training Possible Reviewer Comments: Proposed research designed to increase number and quality of future scientists and engineers in Texas Proposed research involves few students and provides modest training for research or innovation No student involvement in proposed research Capability of the investigator(s) (25%) Student involvement and research training opportunities (15%) Adequacy of institutional commitment and resources (10%) G. Institutional Priority and Available Laboratory Equipment Possible Reviewer Comments: Clear institutional priority with significant institutional support and needed equipment in place A departmental priority with modest support and equipment can reasonably be expected to be in place when needed A topic of interest primarily to the investigator(s) and/or proposed facilities inadequate to do the job F-3 Technology Development and Transfer Program – 2001 Matching Contribution Evaluation Form 1. Is there a letter included from each industrial collaborator indicating that they have read the proposal and are making a financial commitment to the project? Note discrepancies. _______________________________________________________ ________________________________________________________________________ ________________________________________________________________________ Comments: Yes No 2. What support is the industrial collaborator bringing to the project? Cash contributions $__________________________________________________________________________________ In-kind contributions $__________________________________________________________________________________ Following are some examples of in-kind support listed in previous TDT grants. This list is not all-inclusive: Access to/use of equipment, facilities, staff Evaluation and testing, fabrication, installation, processing, manufacturing Consulting, engineering support, assessment of safety or effectiveness Patent application and processing, marketing materials, travel Equipment or materials donation Comments: 3. Is the value of the matching support from the industrial collaborator(s) equal to or greater than the state funds requested? Comments: Yes No 4. The investigator is required to disclose any relationship that might be viewed as a conflict of interest between the university research team and the industrial collaborator on the form Proposal – 5. Do you believe a conflict of interest exists that would compromise the execution of the project or the institution’s interests? Comments: Yes No 5. Is the industrial partner capable of commercializing the technology? Comments: Yes No F-4 Fund – Priority 1 Fund – Priority 2 Do Not Fund Revise Budget Proposal Evaluation Form Merit and soundness of the proposal (45%) Technology Development and Transfer Program ― 2001 Rank (Fund – Priority 1 Proposals only) A. Potential Impact Possible Reviewer Comments: A new technology with wide application that will create new markets A technology that will be important in a narrow range of applications A technology that is interesting but which will have a relatively narrow range of applications Little or no potential impact B. Technological Importance Possible Reviewer Comments: A sophisticated breakthrough technology Interesting but technologically unsophisticated Minimal technological importance C. Plan, Budget and Schedule Possible Reviewer Comments: Well-documented research plan with appropriate budget and time schedule Feasible plan but proposed budget or schedule is 25% over or under what is needed to do the job Feasible plan but proposed budget or schedule is 50% over or under what is needed to do the job Poorly thought out research plan Personnel and Physical Resources Available to the Project (20%) D. Staff Possible Reviewer Comments: Principal investigator has proven record in developing and transferring technology Staff has good records as scientists but little experience in technology transfer Staff inadequately prepared to undertake project E. Facilities Possible Reviewer Comments: Excellent facilities to undertake project Appropriate facilities to undertake project Inadequate facilities to undertake project Technology Transfer Plan (35%) F. Intellectual Property Possible Reviewer Comments: Ownership of intellectual property well defined and protected Legal protection of intellectual property initiated Inadequate protection for intellectual property to allow commercialization G. Industrial Collaborator Possible Reviewer Comments: Strong industrial collaborator willing to commercialize in Texas Industrial collaborator only marginally interested in commercializing in Texas No significant industrial collaboration H. Collaboration Plan Possible Reviewer Comments: Collaborator intimately involved in project with both personnel and financial support Collaborator moderately involved in project with both personnel and financial support Unrealistic collaboration plan F-5 Related reports available: Research Assessment Program, Final Report; July 2000 Advanced Research Program/Advanced Technology Program, Progress Report; August 2000 Evaluation of the Advanced Research and Advanced Technology Programs; January 2001 Advanced Research Program/Advanced Technology Program 2001 Program Announcements, April 2001 Research Expenditures September 1, 2000 - August 31, 2001; April 2002 Related information is also available on the web site of the Texas Higher Education Coordinating Board at: http://www.thecb.state.tx.us http://www.arpatp.com For information about this program contact: Dr. Linda Domelsmith Texas Higher Education Coordinating Board Division of Finance, Campus Planning and Research P.O. Box 12788 Austin, Texas 78711 (512) 427-6150 Internet: Linda.Domelsmith@thecb.state.tx.us The Texas Higher Education Coordinating Board does not discriminate on the basis of race, color, national origin, gender, religion, age or disability in employment or the provision of services. v Printed on Recycled Paper